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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Pancreatic Neoplasms
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Accession:DOID:9003100 term browser browse the term
Synonyms:exact_synonym: Pancreas Neoplasms;   pancreas neoplasm;   pancreatic neoplasm
 xref: NCI:C34035
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Pancreatic Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nek8 NIMA-related kinase 8 ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:20581473 NCBI chr10:63,060,868...63,073,546
Ensembl chr10:63,061,253...63,072,416
JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:21189378 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Stk33 serine/threonine kinase 33 ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:20581473 NCBI chr 1:163,276,176...163,458,580
Ensembl chr 1:163,276,340...163,458,627
JBrowse link
G Ttk Ttk protein kinase ISO ClinVar Annotator: match by term: Pancreatic Neoplasms ClinVar PMID:20581473 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
Adult Pancreatic Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203118 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
duodenal gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Men1 menin 1 ISO associated with Neuroendocrine Tumors; DNA:loss of heterozygosity: : RGD PMID:17135306 RGD:2317341 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
Familial Pancreatic Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 ISO mRNA:increased expression:pancreas, carcinoma (human) RGD PMID:16815451 RGD:5685662 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:8755918 PMID:9443866 PMID:9463314 PMID:9887333 PMID:10330348 More... NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bard1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:25741868 PMID:26315354 PMID:26467025 PMID:26787654 PMID:28135145 More... NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G RGD1311251 similar to RIKEN cDNA 4930550C14 ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:28492532 NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748
JBrowse link
gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1r insulin-like growth factor 1 receptor ISO mRNA and protein: increased expression::poor prognosis for high expression RGD PMID:15867218 RGD:7242847 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Men1 menin 1 ISO DNA:mutations: :
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653 PMID:15944766 RGD:2317354 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity ISO associated with Zollinger-Ellison Syndrome; mRNA:increased expression:tumor (human) RGD PMID:12114431 RGD:2317605 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypomethylation:promoter (human) RGD PMID:17278096 RGD:2317340 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:12114701 PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
Gastro-Enteropancreatic Neuroendocrine Tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase disease_progression ISO associated with Neoplasm Metastasis;mRNA, protein: decreased expression:gastrointestinal system, multiple (human) RGD PMID:22485171 RGD:150340716 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atrx ATRX, chromatin remodeler severity ISO RGD PMID:26026117 RGD:127285385 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Cd53 Cd53 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657
JBrowse link
G Cd86 CD86 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Daxx death-domain associated protein severity ISO RGD PMID:26026117 RGD:127285385 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Eomes eomesodermin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il2rb interleukin 2 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Notch2 notch receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Pou2f2 POU class 2 homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
Glucagonoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btc betacellulin ISO protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G Men1 menin 1 ISO DNA:deletion:exon
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653 PMID:20138042 RGD:2317288 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:12114701 PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Sstr4 somatostatin receptor 4 ISO RGD PMID:8132773 RGD:2324994 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689
JBrowse link
insulinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO protein:increased expression:pancreas, plasma RGD PMID:11331218 RGD:2325319 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Btc betacellulin ISO protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:17982058 RGD:5491180 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO protein:increased expression:pancreas RGD PMID:19013212 RGD:2317608 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Ins2 insulin 2 ISO protein:altered expression:blood
protein:altered localization:pancreas
RGD PMID:8175958 PMID:2565624 RGD:2317266, RGD:2317268 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Men1 menin 1 disease_progression ISO DNA:deletion:exon
CTD Direct Evidence: marker/mechanism
DNA:deletions:exons
CTD PMID:17961653 PMID:12941803 PMID:20138042 PMID:19208834 RGD:2317292, RGD:2317288, RGD:2317310 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO protein:increased expression:pancreas RGD PMID:8972754 RGD:2326080 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Rps15 ribosomal protein S15 IEP RGD PMID:3019805 RGD:61740 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO protein:increased expression:pancreatic B cell
mRNA:decreased expression:pancreatic islet
RGD PMID:12114701 PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Tgfa transforming growth factor alpha ISO protein:increased expression:pancreas RGD PMID:8712689 RGD:2317472 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO mRNA, protein:decreased expression:pancreatic islet RGD PMID:18058603 RGD:2325017 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
Islet Cell Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mafa MAF bZIP transcription factor A ISO ClinVar Annotator: match by term: Islet cell adenomatosis ClinVar
OMIM
PMID:25741868 PMID:29339498 NCBI chr 7:107,432,292...107,435,061
Ensembl chr 7:107,433,605...107,434,690
JBrowse link
islet cell tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler disease_progression ISO protein:decreased expression:pancreas: RGD PMID:24148618 RGD:9586032 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:22761470 RGD:13452384 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Daxx death-domain associated protein disease_progression ISO RGD PMID:21252315 RGD:9587819 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP protein:increased expression:insulinoma (rat) RGD PMID:7925129 RGD:2308920 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
JBrowse link
Islet Cell Tumor Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1b kinesin family member 1B ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:18334619 PMID:18726616 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Mpz myelin protein zero ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:23342407 PMID:24033266 More... NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
JBrowse link
G Ret ret proto-oncogene ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:2660074 PMID:3078962 PMID:7536460 PMID:7824936 PMID:7845675 More... NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12364472 PMID:12618761 PMID:14500403 PMID:15328326 PMID:16199547 More... NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:23342407 PMID:24033266 More... NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:10657297 PMID:11156372 PMID:11526495 PMID:12007193 PMID:12111639 More... NCBI chr 8:50,944,717...50,954,298
Ensembl chr 8:50,944,704...50,954,238
JBrowse link
Melanoma-Pancreatic Cancer Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Melanoma-pancreatic cancer syndrome
ClinVar Annotator: match by term: FAMILIAL ATYPICAL MULTIPLE MOLE MELANOMA-PANCREATIC CARCINOMA SYNDROME
OMIM
ClinVar
PMID:7566978 PMID:7632931 PMID:7647780 PMID:7666917 PMID:7670475 More... NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
non-functioning pancreatic endocrine tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid1a AT-rich interaction domain 1A exacerbates ISO protein:decreased expression:endocrine pancreas (human) RGD PMID:32282764 RGD:126790640 NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
pancreatic acinar cell adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO DNA:missense mutation, gene fusions:multiple (human) RGD PMID:25266736 RGD:13462041 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
pancreatic adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 ISO mRNA:decreased expression:pancreas RGD PMID:11875720 RGD:13831350 NCBI chr 7:106,404,844...106,476,902
Ensembl chr 7:106,404,958...106,476,902
JBrowse link
G Akt3 AKT serine/threonine kinase 3 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:25741868 PMID:28166811 PMID:28492532 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712
JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:25053516 RGD:13462053 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdk4 cyclin-dependent kinase 4 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:25050737 RGD:13782144 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:missense mutations:cds:p.V126D, p.A148T (human)
ClinVar Annotator: match by term: Pancreatic adenocarcinoma
ClinVar PMID:7780957 PMID:8521414 PMID:8595405 PMID:8723678 PMID:9324288 More... RGD:8552283 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:9065402 PMID:9294210 PMID:9500465 PMID:9927029 PMID:10192393 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO RGD PMID:21448932 RGD:11352272 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G E2f1 E2F transcription factor 1 treatment ISO Human cells in a mouse model RGD PMID:28797284 RGD:13838736 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:16397024 PMID:23220880 PMID:26619011 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Gnas GNAS complex locus ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 PMID:7739708 More... NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO RGD PMID:11854392 RGD:14700985 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hrg histidine-rich glycoprotein disease_progression ISO RGD PMID:21713765 RGD:11041886 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Jak1 Janus kinase 1 treatment ISO human cell line in a mouse model RGD PMID:29328487 RGD:13838743 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More... NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:11150980 PMID:12835555 PMID:16155195 PMID:16170316 PMID:16329078 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 treatment
severity
ISO human tissue in a mouse model
protein:increased expression:pancreas (human)
RGD PMID:28849200 PMID:19513748 RGD:13838804, RGD:13838840 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:18042262 PMID:26619011 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk10 mitogen activated protein kinase 10 severity ISO DNA:SNP:intron: (rs2589506) (human) RGD PMID: RGD:13838853 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 exacerbates ISO protein:increased phosphorylation:pancreas (human) RGD PMID:24395444 RGD:150340683 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO RGD PMID:22517435 RGD:14348976 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Med12 mediator complex subunit 12 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr  X:66,404,622...66,427,772
Ensembl chr  X:66,404,760...66,428,387
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 PMID:19336541 More... NCBI chr16:28,228,006...28,621,349 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Plat plasminogen activator, tissue type ISO mRNA:increased expression:pancreas (human) RGD PMID:16733850 RGD:11541045 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 PMID:28492532 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
JBrowse link
G Rac1 Rac family small GTPase 1 treatment ISO human cells in a mouse model RGD PMID:21037555 RGD:14392805 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase treatment ISO human cells in a mouse model RGD PMID:15014358 RGD:14392893 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Ralb RAS like proto-oncogene B treatment ISO human cells in a mouse model RGD PMID:17174914 RGD:14394417 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
JBrowse link
G Ralbp1 ralA binding protein 1 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr 9:105,456,425...105,492,711
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
G Rxra retinoid X receptor alpha ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Sf3b2 splicing factor 3b, subunit 2 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:26619011 NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smad7 SMAD family member 7 severity ISO human cell and construct in a mouse model RGD PMID:10498890 RGD:14394510 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr20:9,742,904...9,753,840
Ensembl chr20:9,742,905...9,753,832
JBrowse link
pancreatic cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4gnt alpha-1,4-N-acetylglucosaminyltransferase ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:16441422 RGD:2325199 NCBI chr 8:100,172,038...100,179,218
Ensembl chr 8:100,172,104...100,178,569
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO mRNA, protein:increased expression:pancreas RGD PMID:19020751 RGD:2317509 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 severity ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648918 PMID:26098869 PMID:20103627 RGD:2317511 NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423
JBrowse link
G Ace angiotensin I converting enzyme ISO RGD PMID:19880966 RGD:2325208 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acvr1 activin A receptor type 1 ISO RGD PMID:9714055 RGD:2317217 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Acvr1b activin A receptor type 1B ISO mRNA:increased expression:pancreas RGD PMID:9714055 PMID:11248065 RGD:2317217, RGD:1598735 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Acvr2a activin A receptor type 2A ISO RGD PMID:9714055 RGD:2317217 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr 2:174,754,631...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 ISO protein:increased expression:pancreas RGD PMID:12428789 RGD:2317573 NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) ISO DNA:polymorphism: :p.R272Q (human) RGD PMID:19068087 RGD:2325313 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adm adrenomedullin disease_progression ISO RGD PMID:17363587 PMID:16841081 RGD:2325317, RGD:2325318 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:serum RGD PMID:20398646 RGD:2325643 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA:increased expression:pancreas RGD PMID:11916627 RGD:2325641 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Ahr aryl hydrocarbon receptor ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:12203118 PMID:25826687 PMID:12203118 RGD:2325664 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 severity
treatment
ISO protein:increased phosphorylation:pancreas (human)
human cells in a mouse model
RGD PMID:20697673 PMID:11595724 RGD:13450953, RGD:13452388 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:16847462 PMID:19506583 RGD:2290476, RGD:5490965 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:18154768 PMID:20508721 RGD:2325678, RGD:2325675 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 ISO protein:decreased expression:pancreas RGD PMID:19216797 RGD:2325688 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO DNA:polymorphism: :p.E504K (human)
DNA:polymorphism (human)
RGD PMID:19068087 PMID:15714130 RGD:2325313, RGD:2325694 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO protein:increased expression:pancreas RGD PMID:12163367 PMID:12481414 RGD:2317524, RGD:2317523 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Ang angiogenin disease_progression ISO mRNA, protein:increased expression:pancreas, serum RGD PMID:8665497 RGD:2325716 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Anxa1 annexin A1 ISO protein:increased expression:pancreas RGD PMID:19173988 PMID:17974280 RGD:2325722, RGD:2325723 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa10 annexin A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO mRNA:increased expression:pancreas RGD PMID:17224646 RGD:2325739 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO DNA:deletions (human)
DNA:mutation, loss of heterozygosity
RGD PMID:1423316 PMID:7478622 RGD:2317208, RGD:2317207 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apoa1 apolipoprotein A1 ISO protein:decreased expression:serum
protein:increased expression:pancreas
RGD PMID:17312459 PMID:17332923 RGD:2325758, RGD:2325757 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoe apolipoprotein E IEP protein:increased expression:pancreas RGD PMID:16215274 RGD:2317552 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Arid1a AT-rich interaction domain 1A ISO RGD PMID:23355908 RGD:8694154 NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arid1b AT-rich interaction domain 1B ISO RGD PMID:23355908 RGD:8694154 NCBI chr 1:45,567,991...45,923,644
Ensembl chr 1:45,563,623...45,923,493
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A ISO DNA:amplification (human) RGD PMID:19145645 RGD:2317557 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330
JBrowse link
G Artn artemin disease_progression ISO mRNA:increased expression:pancreas RGD PMID:20395845 PMID:19304517 RGD:2325815, RGD:2325817 NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025
JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO DNA:SNP:intron:rs664677 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:rs1801516(human)
DNA:SNP: :60G>A(human)
CTD PMID:26098866 PMID:26098869 PMID:16520463 PMID:19147782 PMID:18381943 RGD:2317367, RGD:2317363, RGD:2317234 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atr ATR serine/threonine kinase ISO DNA:SNP: :340C>T (human) RGD PMID:18381943 RGD:2317234 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atrx ATRX, chromatin remodeler ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Axl Axl receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206560 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 ISO mRNA:increased expression:pancreas RGD PMID:14555842 RGD:2317558 NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917
JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO human cells in a mouse model RGD PMID:23523869 RGD:13451129 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag3 BAG cochaperone 3 ISO mRNA:increased expression:pancreas RGD PMID:11513873 RGD:2325843 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bag4 BAG cochaperone 4 ISO mRNA:increased expression:pancreas RGD PMID:10799310 RGD:2325852 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bcl2l1 Bcl2-like 1 severity ISO human gene in a mouse model
CTD Direct Evidence: marker/mechanism
CTD PMID:16904634 PMID:17941720 RGD:11353794 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist ISO RGD PMID:15943879 RGD:2317560 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:18772397 RGD:5490966 NCBI chr11:56,122,697...56,198,060
Ensembl chr11:56,122,750...56,198,059
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase disease_progression ISO human gene in a mouse model RGD PMID:18490924 PMID:22628411 PMID:22871572 RGD:13451537, RGD:13462040, RGD:13461863 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Brca1 BRCA1, DNA repair associated susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Cancer of the pancreas
CTD
ClinVar
OMIM
PMID:7795652 PMID:7837387 PMID:7894493 PMID:8644702 PMID:8723683 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated susceptibility ISO ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2
ClinVar Annotator: match by term: Cancer of the pancreas
CTD Direct Evidence: marker/mechanism
DNA:mutations: :
OMIM
ClinVar
CTD
PMID:8075631 PMID:8524414 PMID:8673090 PMID:8673091 PMID:8673092 More... RGD:9068467 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brip1 BRCA1 interacting helicase 1 ISO ClinVar Annotator: match by term: Pancreatic cancer ClinVar PMID:16116423 PMID:17033622 PMID:21964575 PMID:25330149 PMID:25741868 More... NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B ISO protein:altered localization:pancreas RGD PMID:17242465 RGD:2326105 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Cab39 calcium binding protein 39 disease_progression ISO RGD PMID:28197410 RGD:14398834 NCBI chr 9:86,463,008...86,524,545
Ensembl chr 9:86,463,095...86,524,544
JBrowse link
G Cacybp calcyclin binding protein disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:18765951 RGD:2326146 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:19188911 RGD:2326238 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
JBrowse link
G Capn10 calpain 10 susceptibility ISO DNA:SNP:intron:rs3792267 (human) RGD PMID:20178008 RGD:4107073 NCBI chr 9:93,498,132...93,510,494
Ensembl chr 9:93,498,478...93,510,494
JBrowse link
G Casp8 caspase 8 susceptibility ISO DNA:SNP: :rs1045485 (human)
DNA:deletion, insertion:promoter (human)
RGD PMID:19843670 PMID:18483392 RGD:2317230, RGD:2315744 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 susceptibility
treatment
ISO DNA:snp:promoter:g.-1263A>G (human) RGD PMID:20357690 PMID:19209030 RGD:13451540, RGD:13462046 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase disease_progression ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1 ClinVar PMID:25741868 PMID:28492532 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712
JBrowse link
G Cckar cholecystokinin A receptor IEP
ISO
mRNA:increased expression:pancreas RGD PMID:8222074 PMID:10457335 RGD:4110822, RGD:4110817 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Cckbr cholecystokinin B receptor disease_progression
susceptibility
IEP
IDA
ISO
mRNA:increased expression:pancreas RGD PMID:8302799 PMID:8222074 PMID:1458479 PMID:15688412 RGD:4110823, RGD:4110822, RGD:4110821, RGD:4110829 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057 PMID:10225458 RGD:7483623 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment
ISO human cells in a mouse model
mRNA, protein:increased expression:pancreas (mouse)
RGD PMID:22722256 PMID:11159909 PMID:17541034 RGD:13451541, RGD:13452385, RGD:13462059 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO protein:increased expression:pancreas RGD PMID:12761880 RGD:2317610 NCBI chr 8:114,176,256...114,182,155
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd24 CD24 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd44 CD44 molecule (Indian blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc42 cell division cycle 42 severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:28181096 RGD:13452244 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk4 cyclin-dependent kinase 4 susceptibility
disease_progression
ISO
IEP
protein:increased expression:islet of Langerhans (human)
protein:increased expression:islet of Langerhans, nucleus (rat)
protein:increased expression:pancreas (mouse)
RGD PMID:22761470 PMID:24531709 PMID:22477723 PMID:11159909 RGD:13452384, RGD:13452387, RGD:13452386, RGD:13452385 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:mutations:exon
CTD Direct Evidence: marker/mechanism
CTD PMID:10627132 PMID:26098869 PMID:18772397 RGD:5490966 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20876774 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cftr CF transmembrane conductance regulator no_association
onset
ISO RGD PMID:17072959 PMID:16227367 RGD:2317157, RGD:2317156 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chek1 checkpoint kinase 1 disease_progression ISO DNA:SNP: :35G>A (human) RGD PMID:18381943 RGD:2317234 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Pancreatic cancer ClinVar PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 PMID:11967536 More... NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:19555390 PMID:19793693 RGD:2317583, RGD:2317580 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cycs cytochrome c, somatic ISO RGD PMID:11920648 RGD:2317614 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 susceptibility ISO DNA:transition:5' utr:-34T>C rs743572 (human) RGD PMID:19642097 RGD:2317618 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 EXP CTD Direct Evidence: therapeutic CTD PMID:10026857 PMID:10326030 PMID:10415878 PMID:11332152 PMID:11377651 More... NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Daxx death-domain associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreas
CTD PMID:17443278 PMID:19020767 PMID:18309485 PMID:20072795 RGD:2317630, RGD:2317629 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31838052 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G E2f1 E2F transcription factor 1 treatment IEP RGD PMID:28344092 RGD:13838737 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208748 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression:pancreas RGD PMID:1347773 PMID:19506583 RGD:2317650, RGD:5490965 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27720938 PMID:17452677 PMID:19506583 RGD:5131631, RGD:5490965 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 ISO protein:increased expression:serum (human) RGD PMID:15796914 RGD:10045549 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
G Epcam epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Epha3 Eph receptor A3 ISO RGD PMID:14670182 RGD:2317720 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snp:3' utr:c.*197G>T (rs3212986) (human) RGD PMID:27050953 RGD:13207426 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit treatment ISO pancreatic adenocarcinoma;DNA:SNPs: :rs1799793,rs1052555(human)
DNA,protein:SNPs:exons:rs1799793,rs1052559(human)
RGD PMID:18544627 PMID:21404106 PMID:16458430 RGD:2317223, RGD:11252206, RGD:2317228 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO pancreatic adenocarcinoma;DNA:SNP: :rs1800067(human) RGD PMID:18544627 RGD:2317223 NCBI chr10:2,416,259...2,448,364 JBrowse link
G Etaa1 ETAA1 activator of ATR kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 Ensembl chr14:92,299,553...92,314,104 JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEP protein:increased expression:pancreas RGD PMID:22222375 RGD:9588324 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fanca FA complementation group A ISO DNA,Protein:polymorphisms:exons:c.377C>G, c.661A>G (human) RGD PMID:15591268 RGD:2317735 NCBI chr19:51,304,021...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Fancc FA complementation group C ISO DNA:nonsense mutation (human) RGD PMID:16243825 PMID:15695377 RGD:2317238, RGD:2317239 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376
JBrowse link
G Fancg FA complementation group G ISO RGD PMID:16243825 RGD:2317238 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
JBrowse link
G Faslg Fas ligand severity
resistance
ISO DNA:polymorphism:promoter:-844>>T (human) RGD PMID:11115536 PMID:12370548 PMID:18483392 RGD:2317745, RGD:2317744, RGD:2315744 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf13 fibroblast growth factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Fgf2 fibroblast growth factor 2 severity ISO mRNA:increased expression:pancreas
protein:increased expression:bile
RGD PMID:9293890 PMID:11562741 PMID:11478488 PMID:12670449 RGD:2317762, RGD:2317760, RGD:2317765, RGD:2317759 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand IMP RGD PMID:16528542 RGD:11049499 NCBI chr 1:95,615,056...95,620,463 JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25485836 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Fscn1 fascin actin-bundling protein 1 severity ISO protein:increased expression:pancreas RGD PMID:17696949 RGD:2317785 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16003754 NCBI chr 1:86,305,531...86,312,455 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO CTD Direct Evidence: therapeutic CTD PMID:19003803 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gdnf glial cell derived neurotrophic factor severity ISO RGD PMID:18652760 RGD:2324925 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gli1 GLI family zinc finger 1 ISO RGD PMID:21186299 PMID:18772397 RGD:5491005, RGD:5490966 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gli3 GLI family zinc finger 3 ISO RGD PMID:18772397 RGD:5490966 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:12771991 RGD:2317256 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:SNP:cds:p.I105V (rs1695) (human) RGD PMID:19536452 PMID:19786118 RGD:2317805, RGD:2317804 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hgf hepatocyte growth factor ISO protein:increased expression:serum RGD PMID:20017454 RGD:2317895 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16628086 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 disease_progression ISO RGD PMID:21833720 RGD:10402768 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA, protein:increased expression:pancreas RGD PMID:11815996 RGD:2325165 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:19152246 RGD:2317258 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 susceptibility ISO DNA:polymorphism (human) RGD PMID:19064563 RGD:2306689 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO RGD PMID:14559833 PMID:19732452 PMID:19885860 RGD:2317651, RGD:2317642, RGD:2317640 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Il10 interleukin 10 disease_progression
susceptibility
ISO protein:increased expression:serum
DNA:polymorphism: :-1082G>A (human)
RGD PMID:17235586 PMID:30304975 PMID:30610790 PMID:19250218 RGD:2317655, RGD:14975257, RGD:14975253, RGD:2317653 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 disease_progression ISO protein:increased expression:pancreas RGD PMID:18758789 PMID:12808442 RGD:2317669, RGD:2317670 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 treatment ISO RGD PMID:11748276 RGD:8549514 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:7787209 RGD:2311069 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphisms:promoter:-511C>T, -31T>C (human)
protein:increased expression:serum (human)
RGD PMID:19251436 PMID:7787209 RGD:2317215, RGD:2311069 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:9080118 RGD:8663440 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il24 interleukin 24 ISO CTD Direct Evidence: therapeutic CTD PMID:15580305 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il3 interleukin 3 ISO protein:increased expression:serum RGD PMID:15843207 RGD:2317663 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il4 interleukin 4 disease_progression ISO protein:increased expression:blood RGD PMID:19957810 PMID:12097255 PMID:10404069 RGD:2317261, RGD:2317265, RGD:2317267 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor disease_progression ISO protein:increased expression:pancreas RGD PMID:18758789 RGD:2317669 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 disease_progression ISO RGD PMID:30610790 PMID:30304975 RGD:14975253, RGD:14975257 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilk integrin-linked kinase ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Ins2 insulin 2 susceptibility
disease_progression
ISO associated with Diabetes Mellitus
DNA:Polymorphism:promoter:-23 HphI (human)
associated with Diabetes Mellitus, Non-Insulin-Depend
RGD PMID:19375425 PMID:19152242 PMID:19628082 PMID:19572116 RGD:2317250, RGD:2317253, RGD:2317245, RGD:2317247 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Itga11 integrin subunit alpha 11 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:63,145,950...63,254,717
Ensembl chr 8:63,146,001...63,254,407
JBrowse link
G Itga4 integrin subunit alpha 4 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
JBrowse link
G Itga9 integrin subunit alpha 9 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:118,307,424...118,615,527
Ensembl chr 8:118,307,381...118,613,754
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12385004 PMID:19930156 RGD:5684397 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Klf5 Kruppel-like factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Kras KRAS proto-oncogene, GTPase disease_progression ISO ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12460918 More... RGD:1581761, RGD:5490966, RGD:5490965 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G L1cam L1 cell adhesion molecule treatment ISO RGD PMID:22095073 RGD:11570404 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29384525 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lig3 DNA ligase 3 resistance ISO DNA:SNP:intron:rs 2074522 (human) RGD PMID:19147782 RGD:2317363 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Lig4 DNA ligase 4 susceptibility ISO associated with Diabetes Mellitus;DNA:polymorphism: :54C>T (human) RGD PMID:19147782 RGD:2317363 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Lum lumican disease_progression ISO DNA:SNP: :rs2268578 (human) RGD PMID:19843670 PMID:17671699 RGD:2317230, RGD:2317682 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor no_association ISO DNA:point mutations, deletions:cds:multiple (human)
DNA:polymorphisms: :multiple (human)
RGD PMID:9174057 PMID:17072959 RGD:2325804, RGD:2317157 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO RGD PMID:18772397 RGD:5490966 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Men1 menin 1 ISO associated with Neuroendocrine Tumors; protein:increased expression:multiple organs
CTD Direct Evidence: marker/mechanism
CTD PMID:17961653 PMID:21252315 PMID:17278096 RGD:2317340 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase severity IEP
ISO
protein:increased expression:pancreas (rat)
mRNA:increased expression:pancreas (human)
RGD PMID:9211490 PMID:19506583 PMID:15448002 RGD:2317613, RGD:5490965, RGD:2317235 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A ISO RGD PMID:16434023 RGD:2317701 NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO protein:decreased expression:neuroendocrine tumor (human) RGD PMID:19118063 RGD:2317628 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mir107 microRNA 107 severity ISO RGD PMID:28720759 RGD:14975279 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO protein:increased expression:pancreas RGD PMID:20137856 PMID:20350215 RGD:2317704, RGD:2317703 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
protein:increased activity:pancreatic juice
CTD PMID:30603057 PMID:7635566 PMID:11961486 RGD:2325766, RGD:2325752 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas
protein:increased expression:serum
CTD PMID:22952646 PMID:18445772 PMID:7635566 PMID:19629003 PMID:18030366 RGD:2325849, RGD:2325766, RGD:2325831, RGD:2325854 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase resistance ISO DNA:polymorphism:promoter:-463G>A (human) RGD PMID:18205184 RGD:2317406 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism
associated with Pancreatic Disease; protein:increased expression:pancreas
CTD PMID:11751476 PMID:19843662 PMID:18281514 PMID:17785569 PMID:17019794 RGD:2326052, RGD:2326056, RGD:2326062, RGD:2326060 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
JBrowse link
G Mtap methylthioadenosine phosphorylase ISO DNA, protein:deletion, decreased activity:pancreas: RGD PMID:15534104 RGD:2317952 NCBI chr 5:103,873,020...103,939,406
Ensembl chr 5:103,873,020...103,939,406
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:polymorphism: :677C>T (human) RGD PMID:16737574 RGD:2317120 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23149918 RGD:10040959 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility
no_association
ISO DNA:Polymorphism: :rs1805087 (human) RGD PMID:18843018 PMID:16737574 RGD:2317118, RGD:2317120 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human)
DNA:SNPs:intron, exon:rs162049, p.H595Y (rs10380) (human)
RGD PMID:18843018 PMID:18515090 RGD:2317118, RGD:2325772 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO protein:increased expression:pancreas
protein:increased secretion:bile
RGD PMID:14654947 PMID:18039393 PMID:18383873 PMID:19129927 PMID:19055478 More... RGD:2317984, RGD:2324639, RGD:2324637, RGD:2317987, RGD:2324622, RGD:2324635 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc16 mucin 16, cell surface associated ISO protein:increased expression:serum RGD PMID:19377061 RGD:2325129 NCBI chr 8:16,164,531...16,323,126 JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO mRNA:increased expression:peripheral blood mononuclear cell
protein:increased expression:pancreas
mRNA:increased expression:pancreas
RGD PMID:16274046 PMID:17595659 PMID:20303649 PMID:11751498 PMID:17406026 RGD:2324931, RGD:2324922, RGD:2324914, RGD:2324891, RGD:2324923 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO protein:increased glycosylation:serum
protein:increased expression:pancreas
RGD PMID:19377061 PMID:14654947 RGD:2325129, RGD:2317984 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming ISO protein:increased expression: : RGD PMID:10209489 RGD:2325167 NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25961927 PMID:22024988 RGD:7240699 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 ISO human gene in a mouse model RGD PMID:25071868 RGD:9590074 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism (human)
DNA:polymorphisms,haplotype: :
RGD PMID:18006927 PMID:18006927 PMID:18499698 RGD:2317170, RGD:2317170, RGD:2317168 NCBI chr16:22,218,217...22,238,516 JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphism (human) RGD PMID:18027363 RGD:2317169 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Ncam1 neural cell adhesion molecule 1 severity
disease_progression
ISO RGD PMID:10374842 PMID:11249065 RGD:2326075, RGD:2326074 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:15861417 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngfr nerve growth factor receptor severity ISO mRNA:increased expression:tumor:associated with longer overall survival (human) RGD PMID:16704535 RGD:5508229 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nos2 nitric oxide synthase 2 disease_progression ISO protein:increased expression:pancreas RGD PMID:11196200 PMID:11687972 PMID:15165031 RGD:2325262, RGD:2325257, RGD:2325248 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:17297654 RGD:2325328 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20660371 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20101243 PMID:26098869 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
JBrowse link
G Nrp1 neuropilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15956974 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 severity ISO mRNA:increased expression:tumor:associated with increased tumor aggressiveness (human) RGD PMID:16704535 RGD:5508229 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ISO DNA:mutation:pancreas RGD PMID:16941478 RGD:2325656 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex treatment ISO mRNA:increased expression:pancreas RGD PMID:26045769 PMID:25370920 RGD:11058437, RGD:28867232 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase disease_progression ISO DNA:polymorphism: :2657G>A (human)
DNA:polymorphism: :rs1052133 (human)
RGD PMID:17230526 PMID:18559563 RGD:2317132, RGD:2317130 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Palb2 partner and localizer of BRCA2 susceptibility ISO DNA:nonsense mutations:exon:172_175del, 3116del, 3256C>T (human)
ClinVar Annotator: match by term: Pancreatic cancer 3
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3
ClinVar Annotator: match by term: Cancer of the pancreas
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:16199547 PMID:17200668 PMID:17200671 PMID:17200672 PMID:18302019 More... RGD:2325776 NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990
JBrowse link
G Palld palladin, cytoskeletal associated protein susceptibility ISO DNA, mRNA:missense mutation, increased expression:pancreas:p.P239S (human)
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
protein:increased expression, alternative form:pancreas, fibroblast
ClinVar
CTD
OMIM
PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 PMID:20436683 More... RGD:2325782, RGD:2325779 NCBI chr16:28,228,006...28,621,349 JBrowse link
G Pbrm1 polybromo 1 ISO RGD PMID:23355908 RGD:8694154 NCBI chr16:6,213,507...6,312,895
Ensembl chr16:6,213,300...6,311,780
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO mRNA:increased expression:pancreas RGD PMID:7665222 PMID:14695158 RGD:2324851, RGD:2324850 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19077462 PMID:25086665 PMID:26098869 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pfn1 profilin 1 ISO RGD PMID:16215274 RGD:2317552 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10467400 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Polb DNA polymerase beta disease_progression ISO DNA:polymorphisms: :165A>G, 2133T>C (human) RGD PMID:17230526 RGD:2317132 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta disease_progression ISO RGD PMID:17652168 PMID:17652168 RGD:2324872, RGD:2324872 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma susceptibility ISO DNA:polymorphism: :p.P12A (human)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:11034103 PMID:11741176 PMID:19436234 PMID:19152448 RGD:2317460, RGD:2317462 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptch1 patched 1 ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
CTD PMID:19077462 PMID:19396459 RGD:2324910 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 PMID:19506583 RGD:5490965 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility ISO mRNA, protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-1195A > G, -765G > C (human)
DNA:polymorphisms: :-1195A>A ,-765G>C (human)
CTD PMID:10485483 PMID:10657949 PMID:15705899 PMID:16820089 PMID:19820419 More... RGD:2317179, RGD:5135527, RGD:2317175, RGD:2317184 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Rabl3 RAB, member of RAS oncogene family-like 3 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 5
CTD
OMIM
ClinVar
PMID:31406347 NCBI chr11:63,153,281...63,182,240
Ensembl chr11:63,152,792...63,182,671
JBrowse link
G Rad51 RAD51 recombinase IEP protein:increased expression:pancreas (rat) RGD PMID:20197614 RGD:9831172 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad54l RAD54 like ISO DNA:SNP:exon:rs1048771 (human) RGD PMID:16540687 RGD:2317365 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Rap1gap Rap1 GTPase-activating protein ISO mRNA:decreased expression:pancreas (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:22614916 PMID:16424023 RGD:9835037 NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21699781 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Recql RecQ like helicase ISO DNA:SNPs:introns
DNA:SNP:3'utr:rs13035 (human)
RGD PMID:18422747 PMID:19768149 PMID:16540687 RGD:2317370, RGD:2317369, RGD:2317365 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO RGD PMID:9918209 RGD:2298892 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ret ret proto-oncogene disease_progression ISO protein:increased expression:pancreas RGD PMID:16269310 RGD:2324926 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO RGD PMID:19568409 RGD:2324950 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Runx3 RUNX family transcription factor 3 disease_progression ISO DNA:hypermethylation, loss of heterozygosity (human) RGD PMID:18475302 RGD:2324956 NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G Rxra retinoid X receptor alpha ISO RGD PMID:19152448 RGD:2317462 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase ISO RGD PMID:14508516 RGD:2317190 NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648
JBrowse link
G Serpina1 serpin family A member 1 disease_progression ISO RGD PMID:2323846 RGD:2324960 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Shh sonic hedgehog signaling molecule ISO RGD PMID:19506583 RGD:5490965 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18728667 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Smad2 SMAD family member 2 ISO mRNA:increased expression:pancreas (human) RGD PMID:10505717 RGD:14394490 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Pancreatic cancer
DNA:mutations:exon
OMIM
ClinVar
PMID:8653691 PMID:8898652 PMID:9582123 PMID:9679244 PMID:9811934 More... RGD:5490966 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smad7 SMAD family member 7 ISO mRNA:increased expression:pancreas (human) RGD PMID:10498890 RGD:14394510 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO RGD PMID:23355908 RGD:8694154 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
G Smo smoothened, frizzled class receptor treatment ISO protein:increased expression:pancreas RGD PMID:19460966 PMID:22859707 PMID:19396459 RGD:2324978, RGD:150340554, RGD:2324910 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO RGD PMID:17726579 RGD:2302550 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:15221989 RGD:6478801 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Snw1 SNW domain containing 1 susceptibility ISO DNA:snp:intron: T>A (human) (rs1477261) RGD PMID:20056645 RGD:11035249 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
G Sod1 superoxide dismutase 1 ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 disease_progression
susceptibility
ISO protein:decreased expression:pancreas
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.A16V (human)
CTD PMID:17895890 PMID:12499913 PMID:12700280 PMID:18205184 RGD:2317410, RGD:1581235, RGD:2317406 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19896093 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15970685 RGD:1581363 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
JBrowse link
G Sstr1 somatostatin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
JBrowse link
G Sstr2 somatostatin receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15259086 PMID:17625444 PMID:19917848 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
JBrowse link
G Sstr3 somatostatin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22348037 PMID:23845849 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:25741868 PMID:26098869 PMID:26467025 PMID:28135145 PMID:28492532 More... NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
JBrowse link
G Sycp1 synaptonemal complex protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14991579 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16965396 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
JBrowse link
G Tgfa transforming growth factor alpha ISO
IMP
mRNA, protein:increased expression:pancreas RGD PMID:1401070 PMID:19506583 PMID:17785207 RGD:2317473, RGD:5490965, RGD:2317468 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD PMID:23992306 PMID:18787407 PMID:16933058 RGD:2325015, RGD:2325018 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 disease_progression ISO DNA:deletion, frameshift mutations (human)
DNA:mutations:exon
protein:increased expresssion:pancreas
mRNA:increased expresssion:pancreas
RGD PMID:9850059 PMID:18772397 PMID:11866987 PMID:9365135 RGD:2317501, RGD:5490966, RGD:2317499, RGD:2317502 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30108682 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation (human) RGD PMID:10766168 PMID:20203415 PMID:16757110 RGD:2325028, RGD:2325021, RGD:2325023 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: therapeutic CTD PMID:16211219 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11234897 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 ISO DNA:mutations:exon
ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:1565143 PMID:1565144 PMID:1683921 PMID:7732013 PMID:7887414 More... RGD:5490966 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO RGD PMID:11585747 RGD:2325154 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tsc2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Tymp thymidine phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17443278 PMID:19671868 RGD:2325156 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO protein:increased expression:pancreatic neoplasm (human) RGD PMID:12149149 RGD:5133269 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C no_association ISO DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human)
DNA:polymorphisms: :multiple (human)
RGD PMID:12806614 PMID:17072959 RGD:2317503, RGD:2317157 NCBI chr 9:88,739,577...88,808,465 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO RGD PMID:17652277 RGD:2325162 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfb vascular endothelial growth factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24604347 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation, deletion:promoter (human)
associated with Hippel-Lindau Disease;DNA:missense mutation:exon:p.R238Q (human)
RGD PMID:19690016 PMID:9488521 RGD:2325169, RGD:2325176 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
G Wnt9a Wnt family member 9A ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133
JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19196508 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO DNA:polymorphism:intron:AF076952 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
G Xpo5 exportin 5 ISO mRNA:decreased expression:pancreas (mouse) RGD PMID:26516699 RGD:11041739 NCBI chr 9:14,740,182...14,778,171
Ensembl chr 9:14,740,182...14,778,171
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO DNA:SNP:exon:rs1799782 (human) RGD PMID:16520463 RGD:2317367 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 ISO DNA:polymorphism: :p.R188H (human)
DNA:SNP:exon:rs3218536 (human)
RGD PMID:17986315 PMID:16540687 RGD:2317507, RGD:2317365 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO DNA:SNP:cd:rs861539 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
G Znrf3 zinc and ring finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr14:80,157,854...80,313,456 JBrowse link
pancreatic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11248065 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:3338800 PMID:8808599 PMID:9443866 PMID:9536098 PMID:9887333 More... NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Carcinoma of head of pancreas
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar PMID:9150174 PMID:10667592 PMID:10667595 PMID:12566964 PMID:15024741 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:8665505 PMID:9150150 PMID:9361038 PMID:9536098 PMID:9585613 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brip1 BRCA1 interacting helicase 1 ISO ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
ClinVar PMID:16116423 PMID:17033622 PMID:21964575 PMID:25330149 PMID:25741868 More... NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:28492532 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO RGD PMID:9252195 RGD:8662427 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A susceptibility ISO DNA:insertion:cds:p.R112_L113insR (human) RGD PMID:10922411 RGD:8552383 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Chd3 chromodomain helicase DNA binding protein 3 disease_progression IEP protein:increased expression:pancreas RGD PMID:21472101 RGD:9587766 NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9536098 PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 More... NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:8797827 PMID:9579555 PMID:20221251 PMID:21228398 PMID:21612988 More... NCBI chr10:2,416,259...2,448,364 JBrowse link
G Fance FA complementation group E ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11001585 PMID:17924555 PMID:21279724 PMID:25741868 PMID:26822949 More... NCBI chr20:6,369,416...6,386,631
Ensembl chr20:6,375,573...6,386,631
JBrowse link
G Fancg FA complementation group G ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 severity IEP protein:increased expression:pancreas (rat) RGD PMID:21472101 RGD:9587766 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hoxb13 homeo box B13 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More... NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Kdr kinase insert domain receptor treatment ISO RGD PMID:17414626 RGD:126848809 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISS
ISO
OMIM:260350
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
MouseDO
ClinVar
PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12460918 More... NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:serum RGD PMID:28660759 RGD:24922217 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:25425965 RGD:11570510 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISS OMIM:260350 MouseDO NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nbn nibrin ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9590180 PMID:9620777 PMID:10398434 PMID:10852373 PMID:11093281 More... NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:17200668 PMID:20122277 PMID:20412113 PMID:20582465 PMID:20589654 More... NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:28492532 NCBI chr16:28,228,006...28,621,349 JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEP mRNA:increased expression:pancreas (rat) RGD PMID:2278633 RGD:14392892 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9811458 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G RGD1311251 similar to RIKEN cDNA 4930550C14 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:3338800 PMID:8808599 PMID:9443866 PMID:9536098 PMID:9887333 More... NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748
JBrowse link
G Smad4 SMAD family member 4 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
OMIM:260350
ClinVar
MouseDO
PMID:8653691 PMID:8898652 PMID:9582123 PMID:9679244 PMID:9811934 More... NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11328670 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stk11 serine/threonine kinase 11 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
OMIM:260350
ClinVar
MouseDO
PMID:9536098 PMID:10362809 PMID:11430832 PMID:15188174 PMID:16287113 More... NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Tp53 tumor protein p53 ISO
ISS
ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
OMIM:260350
ClinVar
MouseDO
PMID:1565143 PMID:1565144 PMID:1581912 PMID:1591732 PMID:1631137 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsc1 TSC complex subunit 1 ISO RGD PMID:25425965 RGD:11570510 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
pancreatic ductal adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 ISO protein:increased expression:pancreas RGD PMID:19077459 RGD:2325696 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Ccnd1 cyclin D1 severity ISO DNA:snp:exon:c.870G>A (human)
protein:increased expression:pancreas (human)
RGD PMID:25470788 PMID:22939953 RGD:13462050, RGD:13462062 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdk4 cyclin-dependent kinase 4 severity ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:29735403 RGD:13781899 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G E2f1 E2F transcription factor 1 severity ISO protein:increased expression:pancreatic ductal cell, nucleus (human)
DNA:amplification: : (human)
RGD PMID:12650514 PMID:17233815 PMID:27573434 RGD:13838735, RGD:13838739, RGD:13838738 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 treatment ISO human cells in a mouse model RGD PMID:23535601 RGD:13504844 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta susceptibility ISO RGD PMID:22264792 RGD:13838741 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Jak1 Janus kinase 1 ISO mRNA:decreased expression:pancreatic ductal cell (human) RGD PMID:28677798 RGD:13838745 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 severity
disease_progression
ISO protein:increased phosphorylation:pancreas (mouse) RGD PMID:28837246 PMID:23237571 RGD:14348974, RGD:14348975 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mir155 microRNA 155 disease_progression ISO RGD PMID:28198398 RGD:25314300 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Pgf placental growth factor severity ISO associated with obesity RGD PMID:26861455 RGD:14349030 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:20876794 RGD:14390130 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 severity ISO human cells in a mouse model RGD PMID:15591514 RGD:14390084 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pld1 phospholipase D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:27713167 RGD:14392801 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Rac1 Rac family small GTPase 1 ISO mRNA:increased expression:pancreas (human)
mRNA, protein:increased expression:pancreas (mouse)
RGD PMID:23334332 PMID:21684285 RGD:14392806, RGD:14392816 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rala RAS like proto-oncogene A ISO mRNA:increased expression:pancreas (human) RGD PMID:29113235 RGD:14394418 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Smad2 SMAD family member 2 severity ISO RGD PMID:26908446 RGD:14394493 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
pancreatic ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA, protein:increased expression:pancreas RGD PMID:17481528 RGD:2325211 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin I converting enzyme 2 ISO protein:decreased expression:pancreas RGD PMID:19212105 RGD:2325210 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 disease_progression ISO mRNA:increased expression:pancreas RGD PMID:17979891 RGD:2325243 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 disease_progression ISO protein:altered localization:cytoplasm RGD PMID:14997207 RGD:2325249 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO mRNA:increased expression:pancreas RGD PMID:19609859 RGD:2325659 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:19011933 RGD:2325677 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Anxa2 annexin A2 disease_progression ISO mRNA, protein:increased expression, altered localization:pancreas, plasma membrane RGD PMID:19260470 PMID:16450333 RGD:2317307, RGD:2325731 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa5 annexin A5 ISO protein:increased expression:pancreas RGD PMID:19488907 RGD:2317538 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Anxa8 annexin A8 ISO mRNA:increased expression:pancreas RGD PMID:18223320 RGD:2325735 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043
JBrowse link
G Apoc1 apolipoprotein C1 ISO RGD PMID:15876873 RGD:2325793 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Arg2 arginase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23424623 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreas
protein:increased expression:exocrine pancreas:
RGD PMID:19585519 PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Calr calreticulin ISO protein:increased expression:pancreatic duct RGD PMID:15289361 RGD:2326165 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Cckar cholecystokinin A receptor ISO mRNA:increased expression:pancreatic duct
protein:decreased expression:pancreas
RGD PMID:9239407 PMID:12851875 RGD:4110818, RGD:4110816 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Cckbr cholecystokinin B receptor ISO protein:decreased expression:pancreas RGD PMID:12851875 RGD:4110816 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:17420962 RGD:13462063 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd40 CD40 molecule treatment ISO protein:increased expression:dendritic cell RGD PMID:21436454 PMID:23983255 PMID:20976171 RGD:5490301, RGD:11522743, RGD:5490524 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:24389175 RGD:13782187 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A disease_progression ISO RGD PMID:17671118 RGD:8662851 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24986516 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:15693851 RGD:2317592 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
CTD PMID:29844410 PMID:19424621 RGD:9588974 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO RGD PMID:22919364 RGD:9589121 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr12:35,849,647...35,880,835
Ensembl chr12:35,849,617...35,880,838
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression: : RGD PMID:18505086 RGD:2317644 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Faslg Fas ligand ISO protein:increased expression:pancreas, liver RGD PMID:10547193 PMID:15375495 RGD:2317747, RGD:2317741 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression ISO RGD PMID:12717266 PMID:18704599 RGD:2317758, RGD:2317756 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fscn1 fascin actin-bundling protein 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:12109856 RGD:2317790 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Gpnmb glycoprotein nmb ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gstp1 glutathione S-transferase pi 1 resistance ISO DNA:methylation: :
mRNA, protein:increased expression:pancreas
RGD PMID:16537562 PMID:17265526 PMID:12488200 RGD:2317809, RGD:2317806, RGD:2317811 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdac1 histone deacetylase 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Heatr1 HEAT repeat containing 1 treatment ISO RGD PMID:26676747 RGD:10761108 NCBI chr17:58,051,700...58,093,895
Ensembl chr17:58,051,700...58,093,948
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:20098680 RGD:2317639 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO protein:increased expression:pancreas RGD PMID:14627343 PMID:14506643 RGD:2317649, RGD:2317652 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Il4 interleukin 4 ISO RGD PMID:17942922 RGD:2317264 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor ISO protein:increased expression:pancreas RGD PMID:17942922 RGD:2317264 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Ins2 insulin 2 ISO Glucagon/insulin RGD PMID:19571666 RGD:2317248 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 3:124,406,794...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Jag2 jagged canonical Notch ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 6:131,983,056...132,005,359
Ensembl chr 6:131,983,056...132,005,818
JBrowse link
G Kdm2b lysine demethylase 2B severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:23321669 RGD:9588253 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355
JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25347530 PMID:30654191 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt7 keratin 7 disease_progression ISO RGD PMID:19260470 RGD:2317307 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G L1cam L1 cell adhesion molecule severity ISO protein:increased expression:pancreas (human) RGD PMID:20162456 RGD:6483447 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment ISO human cells in mouse model RGD PMID:20179210 RGD:14348973 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 ISO mRNA, protein:increased expression:pancreatic duct RGD PMID:15548371 RGD:2317697 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Mdm2 MDM2 proto-oncogene onset
severity
ISO DNA:snp:promoter, intron:IVS1+309T>G (human)
protein:increased expression:pancreas (human)
RGD PMID:19752772 PMID:15810085 RGD:2317414, RGD:2317416 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Men1 menin 1 ISO protein:decreased expression:pancreas RGD PMID:19170121 RGD:2317294 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO protein:increased expression:pancreatic duct (human) RGD PMID:7866999 RGD:2317530 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase susceptibility ISO DNA:missense mutation:cds:p.L84F rs12917 (human)
protein:increased activity, increased expression:ductal adenocarcinoma (human)
RGD PMID:16844323 PMID:9393761 RGD:2317648, RGD:2317664 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
JBrowse link
G Mir873 microRNA 873 ISO CTD Direct Evidence: therapeutic CTD PMID:30654191 NCBI chr 5:51,356,919...51,356,995
Ensembl chr 5:51,356,919...51,356,995
JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO protein:increased expression:pancreas RGD PMID:17377415 RGD:2325746 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:pancreas, serum
protein:increased expression:blood
RGD PMID:18706098 PMID:20332475 RGD:2325844, RGD:2325830 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Msln mesothelin disease_progression ISO protein:increased secretion:serum
CTD Direct Evidence: marker/mechanism
DNA:hypomethylation:5'UTR
CTD PMID:14576474 PMID:21775916 PMID:25347530 PMID:19818733 PMID:12874021 RGD:2326055, RGD:2326065 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO protein:increased expression, altered localization:pancreas RGD PMID:14681945 PMID:19109152 PMID:18713982 RGD:2317983, RGD:2324616, RGD:2324633 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc3 mucin 3, intestinal disease_progression ISO mRNA:increased expression:pancreas RGD PMID:12657964 RGD:2324946 NCBI chr12:19,527,251...19,536,924 JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO mRNA:increased expression:pancreas
protein:increased expression:pancreas
RGD PMID:12657964 PMID:16049287 RGD:2324946, RGD:2324942 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming disease_progression ISO mRNA:increased expression:pancreas RGD PMID:7657125 PMID:10227724 RGD:2324986, RGD:2324907 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO mRNA:increased expression:pancreas RGD PMID:7657125 RGD:2324986 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778198 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489257 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO protein:increased expression:pancreas (human) RGD PMID:17492507 RGD:5132867 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nos2 nitric oxide synthase 2 ISO RGD PMID:12660813 RGD:2325254 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 PMID:20484026 PMID:19028876 RGD:2325323, RGD:2325324 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Notch4 notch receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 disease_progression ISO protein:increased expression:pancreas RGD PMID:11295066 PMID:10209957 RGD:2325660, RGD:2325663 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Palld palladin, cytoskeletal associated protein ISO protein:increased expression, alternative form:pancreas, fibroblast RGD PMID:17404500 RGD:2325781 NCBI chr16:28,228,006...28,621,349 JBrowse link
G Pax6 paired box 6 ISO protein:increased expression:pancreatic duct (human) RGD PMID:17849422 RGD:8552381 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component ISO protein:increased expression:pancreatic duct RGD PMID:15856462 RGD:2324870 NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma disease_progression ISO RGD PMID:19396032 RGD:2317461 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18670639 RGD:2317185 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rnf2 ring finger protein 2 ISO protein:increased expression:pancreas RGD PMID:19585519 RGD:9491843 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
JBrowse link
G Rxra retinoid X receptor alpha severity ISO RGD PMID:19396032 RGD:2317461 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Serpina1 serpin family A member 1 ISO mRNA, protein:increased expression:pancreas RGD PMID:12488200 RGD:2317811 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO protein:increased expression:pancreatic duct RGD PMID:19252908 RGD:2324975 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
JBrowse link
G Smad4 SMAD family member 4 disease_progression ISO RGD PMID:15173084 RGD:21066334 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smo smoothened, frizzled class receptor ISO RGD PMID:16826192 RGD:2324981 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26887594 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO RGD PMID:16101174 RGD:2325019 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 disease_progression ISO mRNA:increased expresssion:pancreas RGD PMID:17114585 PMID:10547197 RGD:2317498, RGD:2317500 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation:promoter (human) RGD PMID:12429967 PMID:19065635 RGD:2325025, RGD:2325022 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tmprss3 transmembrane serine protease 3 ISO RGD PMID:14695172 RGD:2325152 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsc2 TSC complex subunit 2 severity ISO RGD PMID:16213898 RGD:11568674 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Tymp thymidine phosphorylase disease_progression ISO RGD PMID:19760965 RGD:2325155 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation:promoter (human) RGD PMID:19065635 RGD:2325022 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
pancreatic endocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:15145354 PMID:25741868 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypermethylation:promoter (human) RGD PMID:14501508 RGD:2317661 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:25741868 NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990
JBrowse link
G Pgf placental growth factor disease_progression
treatment
ISO protein:increased expression:serum (human)
human cells in a mouse model
RGD PMID:23463017 PMID:26861455 RGD:14349029, RGD:14349030 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
pancreatic intraductal papillary-mucinous neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO DNA:missense mutation:cds:p.E17K (human) RGD PMID:24132918 RGD:13462042 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Tp53 tumor protein p53 ISO DNA:missense mutations: :multiple RGD PMID:28930868 RGD:14995501 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
Pancreatic Intraepithelial Neoplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2, protein disulphide isomerase family member ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreatic acinar cell:
protein:increased expression:exocrine pancreas:
RGD PMID:19585519 PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO protein:increased expression:pancreas (human) RGD PMID:12882690 PMID:11751405 RGD:13462061, RGD:13464129 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659