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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Iridocorneal Endothelial Syndrome
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Accession:DOID:9003072 term browser browse the term
Definition:A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.
Synonyms:exact_synonym: Dystrophy Endothelial Cornea;   Dystrophy Endothelial Corneas;   Iridocorneal Endothelial Syndromes;   Iris Atrophy with Corneal Edema and Glaucoma
 primary_id: MESH:D057129
 alt_id: RDO:0007783


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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    syndrome 10833
      Iridocorneal Endothelial Syndrome 0
        Chandler syndrome 0
        Cogan-Reese syndrome 0
Path 2
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18211
      nervous system disease 14059
        Neurologic Manifestations 10039
          sensory system disease 6940
            eye disease 3477
              Hereditary Eye Diseases 1097
                corneal dystrophy 52
                  corneal endothelial dystrophy 10
                    Iridocorneal Endothelial Syndrome 0
                      Chandler syndrome 0
                      Cogan-Reese syndrome 0
paths to the root