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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Chemotherapy-Induced Febrile Neutropenia
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Accession:DOID:9003020 term browser browse the term
Definition:FEVER accompanied by a significant reduction in NEUTROPHIL count associated with CHEMOTHERAPY.
Synonyms:exact_synonym: Chemotherapy-Induced Febrile Neutropenias;   Drug Induced Febrile Neutropenia;   Drug-Induced Febrile Neutropenias
 primary_id: MESH:D064146

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Chemotherapy-Induced Febrile Neutropenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism: : rs1695(human) RGD PMID:25008867 RGD:10755412 NCBI chrNW_004955422:17,914,228...17,916,918
Ensembl chrNW_004955422:17,914,305...17,917,428 		JBrowse link
G Itpa inosine triphosphatase ISO associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:SNP: :rs41320251 (human) RGD PMID:18685564 RGD:10766478 NCBI chrNW_004955415:14,106,786...14,121,975
Ensembl chrNW_004955415:14,107,380...14,121,619 		JBrowse link
G Mbl2 mannose binding lectin 2 disease progression
susceptibility		 ISO associated with Precursor B-Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphisms:exon:
associated with Neoplasms;DNA:SNP,haplotyep:promoter:
associated with leukemia;		 RGD PMID:20930093 PMID:24453114 PMID:24819208 RGD:11530041 RGD:11530043 RGD:11530056 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006 		JBrowse link
G Mdm2 MDM2 proto-oncogene susceptibility ISO associated with Breast Neoplasms;DNA:SNP:cds:309T>G(rs2279744)(human) RGD PMID:21706156 RGD:11073725 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808 		JBrowse link
G Tp53 tumor protein p53 susceptibility ISO associated with Breast Neoplasms;DNA:SNP:cds: p.R72P(rs1042522)(human) RGD PMID:21706156 RGD:11073725 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14316
    disease of anatomical entity 14023
      hematopoietic system disease 3371
        leukocyte disease 1176
          leukopenia 474
            agranulocytosis 439
              neutropenia 436
                Febrile Neutropenia 5
                  Chemotherapy-Induced Febrile Neutropenia 5
Path 2
Term Annotations click to browse term
  disease 14316
    disease of anatomical entity 14023
      Hemic and Lymphatic Diseases 3820
        hematopoietic system disease 3371
          leukocyte disease 1176
            leukopenia 474
              agranulocytosis 439
                Acquired Agranulocytosis 17
                  Drug-Induced Agranulocytosis 17
                    Drug-induced Neutropenia 15
                      Chemotherapy-Induced Febrile Neutropenia 5
paths to the root