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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Chemotherapy-Induced Febrile Neutropenia
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Accession:DOID:9003020 term browser browse the term
Definition:FEVER accompanied by a significant reduction in NEUTROPHIL count associated with CHEMOTHERAPY.
Synonyms:exact_synonym: Chemotherapy-Induced Febrile Neutropenias;   Drug Induced Febrile Neutropenia;   Drug-Induced Febrile Neutropenias
 primary_id: MESH:D064146


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Chemotherapy-Induced Febrile Neutropenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme severity ISO DNA:deletion:intron:IVS16+1464-1751del (human)
associated with acute leukemia;DNA:insertion/deletion:intron 16:		 RGD PMID:15806540 PMID:24819208 RGD:11038917 RGD:11530041 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 susceptibility ISO associated with breast neoplasm;DNA:polymorphism:splice junction:6986A>G (human) RGD PMID:19332043 RGD:11353804 NCBI chr 7:91,621,561...91,654,164
Ensembl chr 7:105,123,437...105,155,322 		JBrowse link
G FCGR3A Fc gamma receptor IIIa treatment ISO associated with Lymphoma, Large B-Cell, Diffuse;DNA:SNP: :rs396991 (human) RGD PMID:27282998 RGD:11344967 NCBI chr 1:137,027,943...137,036,738 JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism: : rs1695(human) RGD PMID:25008867 RGD:10755412 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G ITPA inosine triphosphatase ISO associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:SNP: :rs41320251 (human) RGD PMID:18685564 RGD:10766478 NCBI chr20:3,295,075...3,309,546
Ensembl chr20:3,056,395...3,070,924 		JBrowse link
G MBL2 mannose binding lectin 2 disease progression
susceptibility		 ISO associated with Precursor B-Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphisms:exon:
associated with leukemia;
associated with Neoplasms;DNA:SNP,haplotyep:promoter:		 RGD PMID:20930093 PMID:24453114 PMID:24819208 RGD:11530041 RGD:11530043 RGD:11530056 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432 		JBrowse link
G MDM2 MDM2 proto-oncogene susceptibility ISO associated with Breast Neoplasms;DNA:SNP:cds:309T>G(rs2279744)(human) RGD PMID:21706156 RGD:11073725 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G TP53 tumor protein p53 susceptibility ISO associated with Breast Neoplasms;DNA:SNP:cds: p.R72P(rs1042522)(human) RGD PMID:21706156 RGD:11073725 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15805
    disease of anatomical entity 15483
      hematopoietic system disease 3731
        leukocyte disease 1301
          leukopenia 542
            agranulocytosis 501
              neutropenia 497
                Febrile Neutropenia 9
                  Chemotherapy-Induced Febrile Neutropenia 8
Path 2
Term Annotations click to browse term
  disease 15805
    disease of anatomical entity 15483
      Hemic and Lymphatic Diseases 4218
        hematopoietic system disease 3731
          leukocyte disease 1301
            leukopenia 542
              agranulocytosis 501
                Acquired Agranulocytosis 24
                  Drug-Induced Agranulocytosis 24
                    Drug-induced Neutropenia 21
                      Chemotherapy-Induced Febrile Neutropenia 8
paths to the root