RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Escherichia Coli Infections
Accession: DOID:9002953
browse the term
Definition: Infections with bacteria of the species ESCHERICHIA COLI.
Synonyms: exact_synonym: E coli Infection; E coli Infections; Escherichia coli Infection
primary_id: MESH:D004927 ; RDO:0005534
xref: EFO:1001318
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Abcb1a
ATP binding cassette subfamily B member 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24498193
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
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Ccl4
C-C motif chemokine ligand 4
IEP
mRNA:increased expression:brain
RGD
PMID:16238536
RGD:5683919
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,452,052...68,468,231
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Hba-a1
hemoglobin alpha, adult chain 1
treatment
ISO
RGD
PMID:18786935
RGD:10449443
NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,307,815...15,338,392
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Hba-a2
hemoglobin alpha, adult chain 2
treatment
ISO
RGD
PMID:18786935
RGD:10449443
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,307,815...15,338,392 Ensembl chr10:15,307,815...15,338,392
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Hba-a3
hemoglobin alpha, adult chain 3
treatment
ISO
RGD
PMID:18786935
RGD:10449443
NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481
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Irak3
interleukin-1 receptor-associated kinase 3
treatment
ISO
RGD
PMID:27832756
RGD:34888235
NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121
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Lcn2
lipocalin 2
exacerbates
ISO
protein:increased expression:serum
RGD
PMID:25234944 PMID:25234944 PMID:16446425
RGD:126725084 , RGD:126725084 , RGD:126779557
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095
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Muc2
mucin 2, oligomeric mucus/gel-forming
IEP
RGD
PMID:23798529
RGD:7349358
NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:196,799,517...196,831,756
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Ntrk2
neurotrophic receptor tyrosine kinase 2
onset
IEP
protein:decreased expression:hippocampus
RGD
PMID:21411668
RGD:5684914
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136
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Plac8
placenta associated 8
severity
ISO
RGD
PMID:17404296
RGD:40924563
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
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Rnasel
ribonuclease L
severity
ISO
RGD
PMID:19075243
RGD:40902812
NCBI chr13:68,446,641...68,460,804
Ensembl chr13:65,901,459...65,908,704
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Slc6a4
solute carrier family 6 member 4
ISO
RGD
PMID:19747920
RGD:36947380
NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384
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Tnf
tumor necrosis factor
IEP
protein:increased expression:serum (rat)
RGD
PMID:9466473
RGD:38508904
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
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Tlr2
toll-like receptor 2
ISO
mRNA:increased expression: :
RGD
PMID:12781911
RGD:7794740
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
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Tlr4
toll-like receptor 4
ISO
mRNA:increased expression: :
RGD
PMID:12781911
RGD:7794740
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
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Tlr7
toll-like receptor 7
ISO
mRNA:increased expression: :
RGD
PMID:12781911
RGD:7794740
NCBI chr X:30,644,324...30,670,796
Ensembl chr X:27,027,425...27,054,754
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