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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Hyperphagia
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Accession:DOID:9002916 term browser browse the term
Definition:Ingestion of a greater than optimal quantity of food.
Synonyms:exact_synonym: Overeating;   Polyphagia;   Polyphagias
 primary_id: MESH:D006963


show annotations for term's descendants           Sort by:
Hyperphagia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrp agouti related neuropeptide ISO associated with Diabetes Mellitus, Experimental;mRNA:increased expression:hypothalamus RGD PMID:11179781 RGD:2314004 NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025 		JBrowse link
G Brs3 bombesin-like receptor 3 IMP RGD PMID:9367152 RGD:734661 NCBI chr  X:56,088,434...56,094,118
Ensembl chr  X:56,088,434...56,094,118 		JBrowse link
G Hcrt hypocretin ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27071101 PMID:12535169 RGD:1358429 NCBI chr11:100,652,519...100,653,757
Ensembl chr11:100,651,895...100,653,757 		JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A ISO RGD PMID:12392096 RGD:1624374 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:17567960 RGD:10046043 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO RGD PMID:17567960 RGD:10046043 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Il18 interleukin 18 IMP RGD PMID:16732281 RGD:14695532 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12177191 PMID:25086370 PMID:26186301 PMID:27071101 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lepr leptin receptor ISO CTD Direct Evidence: marker/mechanism
compared to age-matched lean +/fa rats		 CTD
RGD		 PMID:3519326 PMID:15093691 PMID:17229951 PMID:9843879 PMID:26537785 RGD:628910, RGD:12911216 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Mc4r melanocortin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23251400 NCBI chr18:66,990,776...66,993,558
Ensembl chr18:66,990,775...66,993,577 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15494731 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
G Oprd1 opioid receptor, delta 1 ISO RGD PMID:9808678 RGD:9831410 NCBI chr 4:131,834,980...131,872,042
Ensembl chr 4:131,838,037...131,871,797 		JBrowse link
G Oprk1 opioid receptor, kappa 1 ISO RGD PMID:9808678 RGD:9831410 NCBI chr 1:5,658,673...5,676,357
Ensembl chr 1:5,658,689...5,676,354 		JBrowse link
G Oprl1 opioid receptor-like 1 ISO RGD PMID:9808678 PMID:9669488 RGD:9831410, RGD:9835033 NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO RGD PMID:9808678 PMID:21368037 RGD:9831410, RGD:401901088 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198 		JBrowse link
G Penk preproenkephalin ISO RGD PMID:20603139 RGD:10003144 NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819 		JBrowse link
G Pomc pro-opiomelanocortin-alpha ISO DNA:mutations:multiple (human) RGD PMID:15189116 RGD:1357925 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) ISO RGD PMID:10935638 RGD:737762 NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639 		JBrowse link
G Vgf VGF nerve growth factor inducible ISO CTD Direct Evidence: therapeutic CTD PMID:12177191 NCBI chr 5:137,054,156...137,062,205
Ensembl chr 5:137,055,246...137,062,205 		JBrowse link
Bulimia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cck cholecystokinin ISO RGD PMID:8988922 RGD:1625799 NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760 		JBrowse link
G Ghrl ghrelin ISO RGD PMID:15788704 RGD:1642818 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
bulimia nervosa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase susceptibility ISO DNA:SNPs,haplotype: RGD PMID:21300128 RGD:13451125 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602 		JBrowse link
Obesity, Hyperphagia, and Developmental Delay term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: NTRK2-related condition | ClinVar Annotator: match by term: Obesity, hyperphagia, and developmental delay		 OMIM
CTD
ClinVar		 PMID:9536098 PMID:15494731 PMID:17576681 PMID:25741868 PMID:27884935 More... NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16268
    Pathological Conditions, Signs and Symptoms 12656
      Signs and Symptoms 10549
        Digestive Signs and Symptoms 201
          Hyperphagia 22
            Bulimia + 3
            Obesity, Hyperphagia, and Developmental Delay 1
paths to the root