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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Mesothelial Neoplasms
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Accession:DOID:9002899 term browser browse the term
Definition:Neoplasms composed of tissue of the mesothelium, the layer of flat cells, derived from the mesoderm, which lines the body cavity of the embryo. In the adult it forms the simple squamous epithelium which covers all true serous membranes (peritoneum, pericardium, pleura). The concept does not refer to neoplasms located in these organs. (From Dorland, 27th ed)
Synonyms:exact_synonym: Mesothelial Neoplasm
 primary_id: MESH:D018301
 alt_id: RDO:0006122
For additional species annotation, visit the Alliance of Genome Resources.

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Mesothelial Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20371980 PMID:21984916 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408 		JBrowse link
malignant mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26139392 NCBI chr10:36,098,051...36,304,416
Ensembl chr10:36,098,051...36,304,409 		JBrowse link
G Ago1 argonaute RISC component 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:144,444,390...144,479,430
Ensembl chr 5:144,448,792...144,479,306 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613 		JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20682992 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24928783 PMID:25231345 PMID:26463840 PMID:26928227 PMID:29112861, PMID:24928783 RGD:9586039 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor ISO ClinVar Annotator: match by term: Mesothelioma, somatic OMIM
ClinVar		 PMID:9989495 PMID:10380920 PMID:10408400 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16850164 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G C9 complement C9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826 		JBrowse link
G Calb2 calbindin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658 		JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 5:58,159,066...58,166,182
Ensembl chr 5:58,159,066...58,163,584 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Ccne2 cyclin E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:22002241 RGD:11522742 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cdh5 cadherin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:11453316 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19223589 PMID:21526190 PMID:29112861 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cfap45 cilia and flagella associated protein 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr13:90,909,551...90,932,958
Ensembl chr13:90,909,486...90,932,961 		JBrowse link
G Cldn10 claudin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr15:104,026,590...104,115,748
Ensembl chr15:104,026,601...104,115,748 		JBrowse link
G Cldn15 claudin 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr12:22,738,198...22,750,392
Ensembl chr12:22,738,195...22,748,860 		JBrowse link
G Cldn4 claudin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005 		JBrowse link
G Cldn5 claudin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718 		JBrowse link
G Cldn8 claudin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890 		JBrowse link
G Clec11a C-type lectin domain containing 11A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 1:100,290,374...100,293,515
Ensembl chr 1:100,289,295...100,293,558 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368 		JBrowse link
G Copg1 COPI coat complex subunit gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26463840 NCBI chr 4:119,815,041...119,840,997
Ensembl chr 4:119,815,139...119,864,114 		JBrowse link
G Csf1 colony stimulating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560 		JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995 		JBrowse link
G Ddx51 DEAD-box helicase 51 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr12:52,067,183...52,072,249
Ensembl chr12:52,067,183...52,072,108 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Enox2 ecto-NOX disulfide-thiol exchanger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26807072 NCBI chr  X:135,918,938...136,303,267
Ensembl chr  X:135,918,929...136,303,249 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16697254 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G F9 coagulation factor IX ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr  X:143,097,507...143,141,791
Ensembl chr  X:143,097,525...143,141,794 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929 		JBrowse link
G Fgf18 fibroblast growth factor 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391 		JBrowse link
G Fgf9 fibroblast growth factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316 		JBrowse link
G Fn1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fth1 ferritin heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228 		JBrowse link
G Gpr27 G protein-coupled receptor 27 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:132,137,793...132,138,926
Ensembl chr 4:132,137,793...132,138,926 		JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO DNA:deletion:cds (human)
CTD Direct Evidence: marker/mechanism		 CTD PMID:16697254, PMID:7606714 RGD:7495814 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715 		JBrowse link
G Heph hephaestin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516 		JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Icam2 intercellular adhesion molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr10:94,569,889...94,581,218
Ensembl chr10:94,569,890...94,576,512 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23621518 NCBI chr 4:78,744,683...78,879,457
Ensembl chr 4:78,746,547...78,879,294 		JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071 		JBrowse link
G Il3 interleukin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Ilk integrin-linked kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23045294 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610 		JBrowse link
G Limch1 LIM and calponin homology domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843 		JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677 		JBrowse link
G Mcam melanoma cell adhesion molecule disease_progression IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:22784439 PMID:23621518, PMID:23621518 RGD:7364782 NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001 		JBrowse link
G Mdk midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859 		JBrowse link
G Mir125a microRNA 125a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911 		JBrowse link
G Mir126b microRNA 126b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21483773 NCBI chr 3:4,042,488...4,042,560 JBrowse link
G Mir32 microRNA 32 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27716620 NCBI chr 5:73,934,255...73,934,324
Ensembl chr 5:73,934,255...73,934,324 		JBrowse link
G Mir484 microRNA 484 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:27,845...27,921
Ensembl chr10:27,845...27,921 		JBrowse link
G Mlana melan-A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 1:247,869,756...247,883,558
Ensembl chr 1:247,869,756...247,884,442 		JBrowse link
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19190155 PMID:27032653 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408 		JBrowse link
G Mtmr4 myotubularin related protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:74,886,600...74,909,532
Ensembl chr10:74,886,985...74,909,533 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:282,134,676...282,140,370
Ensembl chr 1:282,134,981...282,135,772 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD PMID:16697254, PMID:15993904 RGD:5131858 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570 		JBrowse link
G Nf2 neurofibromin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23435014 PMID:26463840 PMID:26678224 PMID:26928227 PMID:29112861 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523 		JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
G Osmr oncostatin M receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21543585 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Pdpn podoplanin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441 		JBrowse link
G Pllp plasmolipin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr19:10,731,855...10,752,641
Ensembl chr19:10,731,855...10,752,641 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:137,036,936...137,112,930
Ensembl chr 5:137,036,935...137,112,927 		JBrowse link
G Pycard PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:26935421 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699 		JBrowse link
G Rxra retinoid X receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908 		JBrowse link
G Ryr2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606 		JBrowse link
G S100b S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856 		JBrowse link
G Sdc1 syndecan 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016 		JBrowse link
G Sema4f ssemaphorin 4F ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:113,738,225...113,764,532
Ensembl chr 4:113,738,226...113,764,532 		JBrowse link
G Serpina4 serpin family A member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 6:127,743,883...127,753,047
Ensembl chr 6:127,743,971...127,753,046 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224 		JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 2:196,495,867...196,527,412
Ensembl chr 2:196,495,867...196,527,127 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 9:61,594,620...61,634,510
Ensembl chr 9:61,594,620...61,634,510 		JBrowse link
G Shbg sex hormone binding globulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897 		JBrowse link
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:244,615,811...244,783,736
Ensembl chr 1:244,615,821...244,782,706 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20617513 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Tbl1xr1 TBL1X receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 2:107,221,913...107,359,229
Ensembl chr 2:107,233,054...107,359,229 		JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333 		JBrowse link
G Tfdp2 transcription factor Dp-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 8:104,040,795...104,181,228
Ensembl chr 8:104,040,934...104,176,446 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 5:163,186,349...163,231,578
Ensembl chr 5:163,186,349...163,231,578 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Traf7 TNF receptor associated factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr10:13,874,444...13,893,090
Ensembl chr10:13,874,456...13,892,997 		JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752 		JBrowse link
G Ulk2 unc-51 like autophagy activating kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr10:48,050,079...48,129,377
Ensembl chr10:48,050,803...48,129,377 		JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212 		JBrowse link
G Wnt3 Wnt family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793 		JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 PMID:22784439 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564 		JBrowse link
G Wwc1 WW and C2 domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:20,662,996...20,818,500
Ensembl chr10:20,663,541...20,818,128 		JBrowse link
Mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:17659810 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531 		JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21642991 PMID:21874000 PMID:26119930 PMID:26719535 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor ISO ClinVar Annotator: match by null ClinVar PMID:9989495 PMID:10380920 PMID:10408400 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11283936 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15639718 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18301454 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:deletion		 CTD PMID:18379362, PMID:20065947 RGD:7248760 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B IAGP DNA:deletion RGD PMID:20065947 RGD:7248760 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Dio2 iodothyronine deiodinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11425850 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21787763 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Egr1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15878867 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15920167 NCBI chr 3:117,938,500...117,940,219
Ensembl chr 3:117,938,500...117,940,219 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO RGD PMID:16697254 RGD:4889125 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15639718 PMID:17659810, PMID:17659810 RGD:4892302 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Fgf1 fibroblast growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15878867 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15878867 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:14569398 PMID:18038314 NCBI chr15:15,697,292...16,862,873 JBrowse link
G Gdf10 growth differentiation factor 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18949431 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150 		JBrowse link
G Gpc3 glypican 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10656689 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883 		JBrowse link
G Gsn gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15920167 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17290392 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: therapeutic CTD PMID:12768194 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Itln1 intelectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15777968 NCBI chr13:89,919,570...89,929,774
Ensembl chr13:89,919,667...89,929,770 		JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30619488 NCBI chr10:105,781,752...105,787,803
Ensembl chr10:105,781,753...105,787,803 		JBrowse link
G Msln mesothelin ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased secretion:body fluid		 CTD PMID:11751476 PMID:18394747 PMID:20933535, PMID:17785569, PMID:18505465 RGD:2326062, RGD:2326046 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21358348 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:18454162 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
G Myo18b myosin XVIIIb ISO CTD Direct Evidence: therapeutic CTD PMID:17294804 NCBI chr12:49,761,100...49,979,745
Ensembl chr12:49,761,120...49,979,758 		JBrowse link
G Nf2 neurofibromin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12136076 PMID:12168054 PMID:12802287 PMID:16166281 PMID:16319530 PMID:18835652 NCBI chr14:84,996,905...85,088,547
Ensembl chr14:84,996,905...85,088,523 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15920167 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717 		JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:11415934 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285 		JBrowse link
G Pdgfc platelet derived growth factor C ISO CTD Direct Evidence: marker/mechanism CTD PMID:15920167 NCBI chr 2:179,952,227...180,126,897
Ensembl chr 2:179,952,227...180,128,283 		JBrowse link
G Pgr progesterone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15639718 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796 		JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A ISO CTD Direct Evidence: marker/mechanism CTD PMID:18835652 NCBI chr 1:87,224,683...87,232,842
Ensembl chr 1:87,224,677...87,232,848 		JBrowse link
G Puf60 poly-U binding splicing factor 60 ISO CTD Direct Evidence: therapeutic CTD PMID:21435101 NCBI chr 7:117,129,237...117,140,234
Ensembl chr 7:117,129,237...117,140,214 		JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12082623 PMID:15639718 NCBI chr 8:116,307,149...116,318,289
Ensembl chr 8:116,307,141...116,318,289 		JBrowse link
G Slc6a20 solute carrier family 6 member 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17659810 NCBI chr 8:132,713,013...132,753,145
Ensembl chr 8:132,665,927...132,753,292 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9533946 PMID:11283936 PMID:15039138 PMID:17290392 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16221779 PMID:18550471 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901 		JBrowse link
G Syk spleen associated tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17659810 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573 		JBrowse link
G Tnc tenascin C disease_progression ISO RGD PMID:12605648, PMID:16928692 RGD:4889571, RGD:4889612 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12151629 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17316382 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400 		JBrowse link
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by null ClinVar PMID:4332312 PMID:8298644 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16564556 PMID:20705543 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16564556 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348 		JBrowse link
peritoneal mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lats1 large tumor suppressor kinase 1 ISO ClinVar Annotator: match by term: Peritoneal mesothelioma ClinVar NCBI chr 1:1,784,078...1,817,310
Ensembl chr 1:1,784,078...1,817,310 		JBrowse link
G Lats2 large tumor suppressor kinase 2 ISO ClinVar Annotator: match by term: Peritoneal mesothelioma ClinVar NCBI chr15:37,943,609...37,995,175
Ensembl chr15:37,943,609...37,983,882 		JBrowse link
G Mecom MDS1 and EVI1 complex locus ISO ClinVar Annotator: match by term: Peritoneal mesothelioma ClinVar NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769 		JBrowse link
sarcomatoid mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A IAGP DNA:deletion RGD PMID:20065947 RGD:7248760 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16909
    disease of cellular proliferation 6551
      Neoplasms by Histologic Type 4432
        Glandular and Epithelial Neoplasms 3087
          Mesothelial Neoplasms 152
            Mesothelioma + 152
paths to the root