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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Immediate Hypersensitivity
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Accession:DOID:9002850 term browser browse the term
Definition:Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
Synonyms:exact_synonym: Atopic Hypersensitivities;   Atopic Hypersensitivity;   IgE Mediated Hypersensitivity;   IgE-Mediated Hypersensitivities;   Immediate Hypersensitivities;   Type I Hypersensitivities;   Type I Hypersensitivity
 primary_id: MESH:D006969
 alt_id: RDO:0001896
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
Immediate Hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase, liver ISO DNA:SNPs: :multiple (human) RGD PMID:16387594 RGD:5129207 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Arg2 arginase type II ISO DNA:SNP (human) RGD PMID:16387594 RGD:5129207 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 ISO mRNA:increased expression:nasal cavity epithelium RGD PMID:15823807 RGD:2307177 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 ISO mRNA:increased expression:nasal cavity epithelium RGD PMID:15823807 RGD:2307177 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Dhodh dihydroorotate dehydrogenase ISO RGD PMID:9918599 RGD:2316235 NCBI chr 8:110,319,876...110,335,330
Ensembl chr 8:110,317,975...110,335,305
JBrowse link
G Egfr epidermal growth factor receptor ISO DNA:snps:multiple (human) RGD PMID:20357714 RGD:5131868 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 IMP RGD PMID:19188657 RGD:5131872 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr 8:3,730,280...3,744,174
Ensembl chr 8:3,731,737...3,744,175
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 PMID:22967010 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12755381 PMID:20485159 PMID:22967010 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il4ra interleukin 4 receptor, alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 susceptibility ISO Atopy and bronchial hyperresponsiveness, OMIM:147050
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8817330 PMID:20485159 PMID:8817330 RGD:1599903, RGD:1599903 NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) ISO CTD Direct Evidence: marker/mechanism CTD PMID:10733466 NCBI chr17:43,878,885...43,923,093
Ensembl chr17:43,878,989...43,923,092
JBrowse link
G Selp selectin, platelet ISO atopy and bronchial hyperresponsiveness, OMIM:147050 RGD PMID:12929084 RGD:1599904 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 chemokine (C-X-C motif) ligand 15 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl26 chemokine (C-C motif) ligand 26 treatment IDA RGD PMID:25530546 RGD:11081163 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment IMP RGD PMID:23933317 RGD:40903070 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Epx eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO
ISS
MouseDO
RGD
PMID:22397267 RGD:13506905 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 susceptibility ISO
ISS
DNA:polymorphism: MouseDO
RGD
PMID:28380482 RGD:13506910 NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443
JBrowse link
G H2-Pa histocompatibility 2, P region alpha locus susceptibility ISO
ISS
DNA:polymorphism: MouseDO
RGD
PMID:28380482 RGD:13506910 NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797
JBrowse link
G Il25 interleukin 25 treatment IMP RGD PMID:17889290 RGD:40902975 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 exacerbates IEP
IDA
RGD PMID:21592044 PMID:21592044 RGD:126928124, RGD:126928124 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952
JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl17 chemokine (C-C motif) ligand 17 ISO associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 IMP RGD PMID:15951834 RGD:5688155 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 IMP RGD PMID:10946288 RGD:8661731 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator ISO
ISS
DNA:mutations: :
OMIM:103920
MouseDO
RGD
PMID:11243954 RGD:4140482 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO
ISS
associated with cystic fibrosis; DNA:polymorphisms: :DQB1*06:02, DQB1*02:01(human)
OMIM:103920
MouseDO
RGD
PMID:23278646 RGD:36049760 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO
ISS
associated with cystic fibrosis; DNA:polymorphisms: :
OMIM:103920
MouseDO
RGD
PMID:23278646 RGD:36049760 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:7743671 RGD:8547590 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il1a interleukin 1 alpha IEP RGD PMID:8699818 RGD:7794730 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO
ISS
Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
OMIM:103920
DNA:SNP:intron:1011G>A(human)
MouseDO
RGD
PMID:11474427 PMID:16487239 RGD:4889577, RGD:8693711 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G Tlr9 toll-like receptor 9 susceptibility ISO
ISS
IMP
DNA:SNP:promoter:g.-1237T>C rs5743836 (human)
OMIM:103920
MouseDO
RGD
PMID:18275280 PMID:18936185 RGD:5130863, RGD:5130858 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Tnf tumor necrosis factor IEP RGD PMID:8699818 RGD:7794730 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a susceptibility ISO
ISS
DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human)
OMIM:103920
MouseDO
RGD
PMID:20646338 RGD:5131174 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
allergic conjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl11 chemokine (C-C motif) ligand 11 ISO mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 IMP RGD PMID:19553621 RGD:8548840 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 ISO mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 ISO protein:increased expression:conjunctiva RGD PMID:11090473 RGD:6483824 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 IMP RGD PMID:18658092 RGD:6893389 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:8766745 RGD:8547686 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ifng interferon gamma ISO
IMP
RGD PMID:12234900 PMID:16123425 RGD:8142386, RGD:8142391 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il10 interleukin 10 treatment ISO
IMP
protein:increased expression:tear RGD PMID:22092652 PMID:16914468 PMID:15144463 PMID:19060266 RGD:7364837, RGD:11041889, RGD:7365076, RGD:7365027 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 ISO
ISS
associated with Allergic Rhinitis;DNA:SNPs, haplotype:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human) MouseDO
RGD
PMID:9191598 PMID:22023794 RGD:8549533, RGD:8549595 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il1b interleukin 1 beta treatment IEP RGD PMID:9326725 RGD:7401198 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO
ISS
human protein in a mouse model MouseDO
RGD
PMID:10549671 RGD:8549802 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il4ra interleukin 4 receptor, alpha susceptibility ISO
ISS
associated with rhinitis; DNA:SNP: : rs2107356 (human) MouseDO
RGD
PMID:20002627 RGD:4890389 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Irf1 interferon regulatory factor 1 ISO RGD PMID:14605445 RGD:5128787 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Lck lymphocyte protein tyrosine kinase ISO protein:increased phosphorylation:T cell RGD PMID:14507881 RGD:1600225 NCBI chr 4:129,442,137...129,467,434
Ensembl chr 4:129,442,137...129,467,434
JBrowse link
G Muc1 mucin 1, transmembrane severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc2 mucin 2 severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430
JBrowse link
G Muc4 mucin 4 severity ISO
IEP
RGD PMID:17177679 PMID:11581187 RGD:7349351, RGD:7349400 NCBI chr16:32,555,089...32,602,761
Ensembl chr16:32,555,015...32,602,754
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) ISO protein:increased expression:body fluid or substance RGD PMID:21042565 RGD:6482725 NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IMP RGD PMID:16914468 RGD:11041889 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tlr2 toll-like receptor 2 IMP associated with Staphylococcal Infections; RGD PMID:19358332 RGD:8552826 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 IMP
ISO
mRNA,protein:increased expression:conjunctiva: RGD PMID:21820713 PMID:16023216 PMID:21391988 RGD:7777131, RGD:7794849, RGD:7794770 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tlr9 toll-like receptor 9 ISO mRNA,protein:decreased expression:conjunctiva: RGD PMID:16023216 RGD:7794849 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Tnc tenascin C ISO
ISS
DNA:SNPs: :multiple (human) MouseDO
RGD
PMID:18305139 RGD:4889589 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252
JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A severity ISO
ISS
DNA:snp:exon:c.1236C>T (human)
OMIM:607154
MouseDO
RGD
PMID:24040855 RGD:8657076 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 no_association ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 treatment ISO RGD PMID:23089405 RGD:7248414 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl26 chemokine (C-C motif) ligand 26 ISO protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423
JBrowse link
G Cd40 CD40 antigen ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 treatment IDA RGD PMID:10436391 RGD:11344920 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV susceptibility ISO
ISS
DNA:polymorphism:exon:p.F158V(rs396991)(human)
OMIM:607154
MouseDO
RGD
PMID:18199088 RGD:5508449 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070
JBrowse link
G Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 3:80,588,757...80,711,534
Ensembl chr 3:80,588,757...80,710,142
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 ISO RGD PMID:20487636 RGD:5144132 NCBI chr17:37,581,094...37,585,376
Ensembl chr17:37,581,111...37,585,375
JBrowse link
G Hrh1 histamine receptor H1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr 6:114,374,897...114,460,259
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Ifng interferon gamma treatment ISO associated with Asthma RGD PMID:12787306 PMID:18510219 RGD:7829803, RGD:10755770 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il10 interleukin 10 treatment ISO
IDA
RGD PMID:23883806 PMID:23253209 RGD:7364793, RGD:7364818 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 susceptibility
no_association
ISO DNA:polymorphism:exon:c. 2044G>A (human)
ClinVar Annotator: match by term: Allergic rhinitis
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.R130Q (rs20541) (human)
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)
DNA:SNP:promoter:-1512A>C (rs1881457) (human)
ClinVar
CTD
OMIM
RGD
PMID:10699178 PMID:12928861 PMID:15356556 PMID:15483090 PMID:15711639 More... RGD:4152796, RGD:8549518, RGD:8549516, RGD:8549501 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:146,166,474...146,214,982
Ensembl chr  X:146,166,472...146,212,188
JBrowse link
G Il17a interleukin 17A susceptibility ISO
ISS
DNA:snp:promoter:c.-444A>G (human)
OMIM:607154
mRNA:increased expression:peripheral blood mononuclear cell (human)
MouseDO
RGD
PMID:22507625 PMID:21535180 RGD:9068429, RGD:5147409 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il18 interleukin 18 severity
no_association
ISO
ISS
DNA:SNP:promoter:-137G>C (rs187238) (human)
OMIM:607154
DNA:SNP:promoter:-140C>G (rs360721) (human)
MouseDO
RGD
PMID:22840759 PMID:22840759 RGD:8655914, RGD:8655914 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:12592663 RGD:8662963 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il4 interleukin 4 treatment ISO RGD PMID:9893928 PMID:24620662 PMID:8908280 PMID:14653048 RGD:7829796, RGD:11522769, RGD:7829827, RGD:7829802 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 treatment ISO RGD PMID:23934070 PMID:24620662 RGD:11354976, RGD:11522769 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Itgb2 integrin beta 2 treatment ISO RGD PMID:12046991 RGD:9698435 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Muc1 mucin 1, transmembrane severity ISO mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 PMID:31425778 PMID:31425778 RGD:127345100, RGD:127345100, RGD:127345100 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric ISO mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Pon1 paraoxonase 1 severity ISO protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I ISO protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr19:30,541,887...31,742,667
Ensembl chr19:30,541,889...31,742,433
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 IEP mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322
JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility ISO
ISS
DNA:SNP: :rs7726552 (human)
OMIM:607154
MouseDO
RGD
PMID:21410962 RGD:5144225 NCBI chr18:43,897,346...43,900,464
Ensembl chr18:43,897,354...43,900,464
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 IEP mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Tacr1 tachykinin receptor 1 ISO mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO RGD PMID:31368266 RGD:14995445 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tlr2 toll-like receptor 2 severity ISO
ISS
IDA
DNA:polymorphism:cds:p.R753Q(human)
OMIM:607154
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:
MouseDO
RGD
PMID:22402138 PMID:22555057 PMID:18381801 PMID:18219831 RGD:7800732, RGD:8552993, RGD:8552972, RGD:7800742 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 severity
treatment
susceptibility
no_association
ISO
ISS
DNA:polymorphism:cds:p.D299G(human)
OMIM:607154
protein:increased expression:nasal lavage,leukocyte, bone marrow:
protein:decreased expression:nasal mucosa:
DNA:SNP: :rs1927911(human)
DNA:polymorphism: :4216G>C(human)
MouseDO
RGD
PMID:22402138 PMID:22555057 PMID:22577387 PMID:17069098 PMID:23639307 More... RGD:7800732, RGD:8552993, RGD:7800740, RGD:7800738, RGD:7800736, RGD:4145354 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tlr9 toll-like receptor 9 ISO protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr19:39,378,000...39,451,547
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 treatment ISO associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr19:39,102,342...39,175,200
Ensembl chr19:39,102,342...39,175,516
JBrowse link
G Il3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
JBrowse link
Anaphylaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenergic receptor, beta 1 disease_progression ISO RGD PMID:20959119 RGD:6893644 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO RGD PMID:1422942 RGD:8548893 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Aspg asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:65671 NCBI chr12:112,073,117...112,094,007
Ensembl chr12:112,073,113...112,093,993
JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319
JBrowse link
G Cabs1 calcium binding protein, spermatid specific 1 treatment ISO RGD PMID:25632019 RGD:14400306 NCBI chr 5:88,127,310...88,129,400
Ensembl chr 5:88,127,298...88,129,403
JBrowse link
G Cma1 chymase 1, mast cell ISO protein:increased expression:lung, mast cell (human) RGD PMID:17081716 RGD:5128820 NCBI chr14:56,178,908...56,182,132
Ensembl chr14:56,178,908...56,182,132
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III susceptibility ISO associated with Agammaglobulinemia;DNA:mutation:splice junction: RGD PMID:23545275 PMID:26396093 RGD:11040993, RGD:11040995 NCBI chr 1:170,878,738...170,893,476
Ensembl chr 1:170,878,743...170,892,504
JBrowse link
G Grap2 GRB2-related adaptor protein 2 ameliorates IMP RGD PMID:18664516 RGD:126790488 NCBI chr15:80,456,798...80,537,055
Ensembl chr15:80,456,795...80,537,055
JBrowse link
G Hdac3 histone deacetylase 3 IMP RGD PMID:24619412 RGD:9590165 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hp haptoglobin ISO RGD PMID:12147031 RGD:11041789 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Il4 interleukin 4 IEP
ISO
mRNA:increased expression:lung, intestine, spleen
associated with cystic echinococcosis; protein:increased expression:blood
RGD PMID:24468678 PMID:28095662 RGD:10402796, RGD:14696684 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7623993 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10934231 NCBI chr14:56,003,419...56,005,949
Ensembl chr14:56,003,419...56,005,951
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19767079 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO
IMP
RGD PMID:18480553 PMID:17822719 RGD:2300247, RGD:1642600 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO RGD PMID:21604443 RGD:7207802 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Wfdc6a WAP four-disulfide core domain 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20693069 NCBI chr 2:164,421,439...164,427,704
Ensembl chr 2:164,421,439...164,427,367
JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacng6 calcium channel, voltage-dependent, gamma subunit 6 susceptibility ISO
ISS
DNA:SNP,haplotype:rs192808(human) MouseDO
RGD
PMID:20860846 RGD:13524562 NCBI chr 7:3,472,017...3,484,183
Ensembl chr 7:3,472,711...3,484,183
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20485159 PMID:20022477 RGD:4145619 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15970796 RGD:5144000 NCBI chr14:73,263,515...73,286,554
Ensembl chr14:73,263,043...73,286,554
JBrowse link
G Fancc Fanconi anemia, complementation group C ISO
ISS
DNA:haplotype::rs4647416(human) MouseDO
RGD
PMID:21670957 RGD:11045795 NCBI chr13:63,452,519...63,645,126
Ensembl chr13:63,432,857...63,645,092
JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha susceptibility ISO
ISS
MouseDO
RGD
PMID:25975240 RGD:11074090 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO
ISS
MouseDO
RGD
PMID:25975240 RGD:11074090 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO
ISS
MouseDO
RGD
PMID:25975240 RGD:11074090 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G Il4 interleukin 4 susceptibility ISO
ISS
DNA:SNPs:promoter,5'UTR,intron:multiple MouseDO
RGD
PMID:20921925 RGD:11528633 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Ltc4s leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083
JBrowse link
G Postn periostin, osteoblast specific factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr19:10,901,883...10,919,875
Ensembl chr19:10,914,524...10,919,875
JBrowse link
G Ptger2 prostaglandin E receptor 2 (subtype EP2) ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15496426 PMID:16502481 NCBI chr14:45,225,568...45,241,277
Ensembl chr14:45,225,652...45,241,277
JBrowse link
G Ptgir prostaglandin I receptor (IP) ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 7:16,640,415...16,644,830
Ensembl chr 7:16,640,415...16,644,830
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:9487340 RGD:5143936 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) ISO
ISS
MouseDO
RGD
PMID:21796142 RGD:5147839 NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295
JBrowse link
G Tbx21 T-box 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15806396 PMID:16502481 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15898979 RGD:11059537 NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006
JBrowse link
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 IMP RGD PMID:18931056 RGD:5128825 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) no_association ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:16008680 PMID:19771478 RGD:5128831, RGD:5128835 NCBI chr 2:26,732,508...26,755,007
Ensembl chr 2:26,732,515...26,754,991
JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 susceptibility ISO
ISS
DNA:polymorphism (human)
OMIM:600807
MouseDO
RGD
PMID:19383228 PMID:19484664 RGD:4140919, RGD:4140913 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO
ISS
DNA:hypermethylation:promoter
OMIM:600807
MouseDO
RGD
PMID:19221603 RGD:13831295 NCBI chr 1:78,635,542...78,685,460
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Ada adenosine deaminase susceptibility ISO
ISS
DNA:polymorphisms (human)
OMIM:600807
MouseDO
RGD
PMID:16754522 RGD:5128848 NCBI chr 2:163,568,491...163,592,161
Ensembl chr 2:163,568,504...163,592,159
JBrowse link
G Adam33 a disintegrin and metallopeptidase domain 33 susceptibility
no_association
disease_progression
ISO
ISS
IEP
DNA:SNPs: :multiple (human)
OMIM:600807
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :p.M764T (human)
mRNA:increased expression:lung
DNA:SNPs (human)
MouseDO
RGD
PMID:18778489 PMID:15118671 PMID:16893396 PMID:17339047 PMID:17961406 More... RGD:4145378, RGD:1331525, RGD:4145382, RGD:4145380, RGD:4145379, RGD:4145360, RGD:4145359 NCBI chr 2:130,892,739...130,905,734
Ensembl chr 2:130,892,511...130,905,734
JBrowse link
G Adam8 a disintegrin and metallopeptidase domain 8 severity ISO
IEP
IMP
mRNA:increased expression:bronchus
mRNA:increased expression:respiratory tract
RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380, RGD:5128878, RGD:5128872 NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475
JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr13:68,768,162...69,147,719
Ensembl chr13:68,768,162...69,147,660
JBrowse link
G Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr 6:55,428,486...55,478,440
Ensembl chr 6:55,428,963...55,478,436
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO
ISS
IMP
OMIM:600807
protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :rs1154404, rs28730619 (human)
MouseDO
RGD
PMID:19514054 PMID:19395503 PMID:17543375 PMID:15919956 RGD:5128890, RGD:5128891, RGD:5128882, RGD:5128892 NCBI chr 3:138,142,961...138,161,260
Ensembl chr 3:138,148,854...138,161,260
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IMP RGD PMID:19168697 RGD:5686821 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adora1 adenosine A1 receptor ISO
ISS
IMP
DNA:SNPs: :1405C>T (human)
OMIM:600807
protein:increased expression:bronchus
MouseDO
RGD
PMID:19019667 PMID:20400685 PMID:17959644 RGD:4890386, RGD:4145444, RGD:5129097 NCBI chr 1:134,126,953...134,163,195
Ensembl chr 1:134,126,961...134,163,169
JBrowse link
G Adora2a adenosine A2a receptor ISO
ISS
IMP
IDA
IEP
DNA:SNP (human)
OMIM:600807
mRNA:decreased expression:aorta
MouseDO
RGD
PMID:19019667 PMID:17293374 PMID:16339780 PMID:18310516 RGD:4890386, RGD:4890380, RGD:4890385, RGD:4890366 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Adrb2 adrenergic receptor, beta 2 susceptibility ISO
IMP
ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
CTD Direct Evidence: marker/mechanism
DNA:SNP: :-1023A>G (human)
DNA:SNPs: :p.R16G, p.Q27E (human)
DNA:polymorphism: :p.R16G (human)
DNA:SNPs:promoter:multiple (human)
DNA:SNP: :p.Q27E (human)
ClinVar
CTD
OMIM
RGD
PMID:8383511 PMID:15284533 PMID:16596417 PMID:1655856 PMID:15118671 More... RGD:5129113, RGD:1331525, RGD:4145081, RGD:4145094, RGD:4145092, RGD:4145108, RGD:4145105, RGD:4145061, RGD:4145096, RGD:4145107 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment
onset
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)
CTD
RGD
PMID:23304218 PMID:33075463 PMID:21920897 PMID:23304218 RGD:7244279, RGD:6767554, RGD:7244279 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP
ISO
RGD PMID:17877756 PMID:19080339 RGD:5147452, RGD:5147457 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 PMID:15118671 RGD:1331525 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Alox15 arachidonate 15-lipoxygenase IEP
IMP
protein:increased expression:lung RGD PMID:19628725 PMID:18692885 RGD:5509605, RGD:5509784 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Alox5 arachidonate 5-lipoxygenase no_association
susceptibility
treatment
severity
ISO
IMP
IEP
IDA
DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood, leukocyte
protein:increased expression:lung
DNA:repeat:promoter (human)
DNA:polymorphism:cds:p.E254K (human)
CTD
OMIM
RGD
PMID:20128419 PMID:10369259 PMID:9642160 PMID:12911785 PMID:8879219 More... RGD:4890407, RGD:734557, RGD:5147467, RGD:5147465, RGD:5147462, RGD:4890422, RGD:4890408, RGD:4890415, RGD:4890410, RGD:4890413 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein susceptibility
no_association
ISO
ISS
IMP
IEP
DNA:SNP: :rs10507391 (human)
OMIM:600807
mRNA:increased expression:blood, leukocyte
DNA:repeat:promoter:-169(A)21 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
protein:increased expression:lung
DNA:polymorphism:promoter (human)
DNA:SNPs (human)
MouseDO
RGD
PMID:20067482 PMID:9642160 PMID:10527888 PMID:12911785 PMID:15784112 More... RGD:4890405, RGD:5147467, RGD:5147466, RGD:5147465, RGD:5147464, RGD:5147462, RGD:4890422, RGD:4890407, RGD:4890409 NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
JBrowse link
G Ambp alpha 1 microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036
JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 severity ISO protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr14:51,328,534...51,339,466
Ensembl chr14:51,328,607...51,339,466
JBrowse link
G Anxa1 annexin A1 IMP RGD PMID:22092555 RGD:7421657 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Arg1 arginase, liver ISO
IEP
DNA:SNP: :rs2781667 (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:lung, mononuclear cell (human)
mRNA:increased expression:lung (mouse)
CTD
RGD
PMID:19281908 PMID:19800904 PMID:20124949 PMID:12813022 PMID:12813022 RGD:5129205, RGD:4143187, RGD:4143187 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Arg2 arginase type II severity
susceptibility
ISO
IEP
DNA:SNP: :rs3742879, rs17249437 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:SNPs (human)
CTD
RGD
PMID:19281908 PMID:20124949 PMID:12813022 PMID:16387594 RGD:5129205, RGD:4143187, RGD:5129207 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 onset ISO
ISS
DNA:polymorphism:exon (human)
OMIM:600807
protein:increased expression:blood, eosinophil
MouseDO
RGD
PMID:11517947 PMID:8856156 PMID:14727005 PMID:19038786 RGD:4890456, RGD:4891042, RGD:4890454, RGD:4891028 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G Bdnf brain derived neurotrophic factor susceptibility
severity
ISO
ISS
protein:decreased expression:blood, eosinophil
OMIM:600807
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
protein:increased expression:plasma
DNA:polymorphisms: :p.V66M (rs6265) (human)
MouseDO
RGD
PMID:12752594 PMID:21723144 PMID:17584309 PMID:20874832 PMID:19895626 More... RGD:4891122, RGD:8655967, RGD:4891067, RGD:4891063, RGD:4891117, RGD:4891123 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bglap bone gamma carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bmpr1b bone morphogenetic protein receptor, type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 3:141,540,230...141,875,335
Ensembl chr 3:141,542,897...141,875,186
JBrowse link
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173
JBrowse link
G C3 complement component 3 severity IMP
ISS
ISO
IEP
OMIM:600807
protein:increased expression:serum
DNA:SNP:intron:rs11569562 (human)
DNA:SNP: :4896C>T (human)
protein:increased expression:respiratory system fluid/secretion
Interaction with IL4RA
DNA:SNPs: :multiple (human)
MouseDO
RGD
PMID:11591733 PMID:20589464 PMID:18566738 PMID:15278436 PMID:20802484 More... RGD:5129517, RGD:5129519, RGD:5129501, RGD:5129512, RGD:5129681, RGD:5129537, RGD:5129538, RGD:5129505 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G C3ar1 complement component 3a receptor 1 severity ISO
ISS
IMP
IEP
OMIM:600807
mRNA:increased expression:lung
protein:increased expression:lung, leukocyte
MouseDO
RGD
PMID:15278436 PMID:20802484 PMID:20045013 PMID:17544263 PMID:15940127 More... RGD:5129512, RGD:5129681, RGD:5129686, RGD:5129560, RGD:5129561, RGD:5129560 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120
JBrowse link
G C5ar1 complement component 5a receptor 1 severity IMP
IEP
ISO
protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract
RGD PMID:16511606 PMID:20802484 PMID:17544263 PMID:15940127 RGD:5130166, RGD:5129681, RGD:5129560, RGD:5129561 NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465
JBrowse link
G Card11 caspase recruitment domain family, member 11 susceptibility IMP
ISO
ClinVar Annotator: match by term: Asthma ClinVar
RGD
PMID:18323416 PMID:23129749 PMID:25741868 PMID:28492532 PMID:16751370 RGD:11100037 NCBI chr 5:140,858,754...140,986,351
Ensembl chr 5:140,858,745...140,986,337
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 9:21,458,168...21,500,763
Ensembl chr 9:21,458,190...21,503,919
JBrowse link
G Casp1 caspase 1 ISO protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Cat catalase severity ISO
IDA
DNA:polymorphism:promoter:-21A>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased activity
DNA:polymorphism:promoter:-262C>T (human)
protein:increased expression:erythrocyte
CTD
RGD
PMID:18048809 PMID:19373626 PMID:16622028 PMID:18048809 PMID:19475625 RGD:5130753, RGD:5130867, RGD:5130856, RGD:5130751 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl1 chemokine (C-C motif) ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 susceptibility
treatment
severity
ISO
IEP
IMP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.A23T (human)
mRNA:increased expression:lung
CTD
OMIM
RGD
PMID:16304252 PMID:22932891 PMID:17074272 PMID:17845580 PMID:20704746 More... RGD:5130930, RGD:7248416, RGD:4145461, RGD:4145457, RGD:4145387, RGD:4145392, RGD:4145451, RGD:4891485 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl17 chemokine (C-C motif) ligand 17 ISO
IMP
IEP
IDA
mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:15993846 PMID:11160256 PMID:20074456 PMID:15947487 PMID:20237293 RGD:2306304, RGD:4145603, RGD:4145487, RGD:4145513, RGD:4145486 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccl19 chemokine (C-C motif) ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr 4:42,754,525...42,756,365
Ensembl chr 4:42,754,525...42,756,577
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 severity
treatment
ISO
IEP
IDA
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:haplotype::-2518A>G (human)
protein:increased expression:lung
CTD
RGD
PMID:19373627 PMID:19373627 PMID:12055264 PMID:25441643 PMID:23454776 More... RGD:4891466, RGD:11528570, RGD:11528569, RGD:8551842, RGD:2307055, RGD:4145509 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum
RGD PMID:18422729 PMID:22469443 RGD:7483597, RGD:7483618 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
JBrowse link
G Ccl22 chemokine (C-C motif) ligand 22 IMP
ISO
IEP
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:10384142 PMID:18684970 PMID:15993846 PMID:18316417 RGD:4891475, RGD:4145489, RGD:2306304, RGD:4891474 NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327
JBrowse link
G Ccl24 chemokine (C-C motif) ligand 24 susceptibility ISO
ISS
IMP
DNA:SNPs: :179T>C, 275C>T (human)
OMIM:600807
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :1265A>G (human)
protein:increased expression:plasma
MouseDO
RGD
PMID:15207712 PMID:17548626 PMID:18712274 PMID:12952266 PMID:12761043 More... RGD:4891495, RGD:4891484, RGD:4891483, RGD:4891496, RGD:5130932, RGD:4891485, RGD:5130930 NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
JBrowse link
G Ccl26 chemokine (C-C motif) ligand 26 treatment ISO
ISS
IDA
protein:increased expression:plasma
OMIM:600807
DNA:SNPs: :77C>T, 2497T>G (human)
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
MouseDO
RGD
PMID:16304252 PMID:25399816 PMID:25530546 PMID:15207712 PMID:18712274 RGD:5130930, RGD:11087575, RGD:11081163, RGD:4891495, RGD:4891483 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423
JBrowse link
G Ccl27a chemokine (C-C motif) ligand 27A ISO RGD PMID:19541356 RGD:5130899 NCBI chr 4:41,769,467...41,774,251
Ensembl chr 4:41,769,467...41,774,247
JBrowse link
G Ccl28 chemokine (C-C motif) ligand 28 IEP mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr13:120,085,355...120,115,895
Ensembl chr13:120,085,355...120,115,895
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 ISO RGD PMID:18774390 RGD:5130915 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 susceptibility IEP
ISO
protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:smooth muscle cell
DNA:transition:5' utr:-403G>A (human)
CTD
RGD
PMID:8534483 PMID:20092989 PMID:18208670 PMID:20430255 RGD:4891430, RGD:2307112, RGD:4891381 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 ISO
IEP
RGD PMID:21388664 PMID:19965981 RGD:5130983, RGD:5130979 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 severity IEP
IMP
mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections
RGD PMID:15654816 PMID:15593301 RGD:5688158, RGD:5688159 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 susceptibility ISO
ISS
IEP
DNA:SNP:cds:p.V64I (human)
OMIM:600807
DNA:haplotype:cds:p.V64I(human)
protein:increased expression:lung, dendritic cell (mouse)
MouseDO
RGD
PMID:17298432 PMID:23454776 PMID:19917684 RGD:4145110, RGD:8551842, RGD:8549811 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 IMP
ISS
ISO
IDA
OMIM:600807
protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)
MouseDO
RGD
PMID:18699933 PMID:19017998 PMID:17145927 PMID:16978084 PMID:20220260 More... RGD:4145633, RGD:4145632, RGD:1601020, RGD:4145646, RGD:4145638, RGD:4145623, RGD:4145618 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Ccr4 chemokine (C-C motif) receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 no_association IMP
ISS
ISO
IEP
OMIM:600807
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
mRNA:increased expression:lung (mouse)
protein:decreased expression:blood, lymphocyte (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
MouseDO
RGD
PMID:16474097 PMID:23454776 PMID:18094012 PMID:15256090 PMID:20220260 RGD:4892093, RGD:8551842, RGD:4892088, RGD:4892108, RGD:4145638 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Ccr6 chemokine (C-C motif) receptor 6 IEP protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
JBrowse link
G Ccr7 chemokine (C-C motif) receptor 7 IEP protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903
JBrowse link
G Ccr8 chemokine (C-C motif) receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 9:119,921,199...119,923,972
Ensembl chr 9:119,921,180...119,923,972
JBrowse link
G Ccr9 chemokine (C-C motif) receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr 9:123,596,276...123,612,522
Ensembl chr 9:123,507,504...123,613,395
JBrowse link
G Cd14 CD14 antigen severity
no_association
susceptibility
ISO DNA:polymorphism:promoter:c. -260C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:c. -159C>T (human)
DNA:SNPs: :
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
CTD
RGD
PMID:17607003 PMID:15940135 PMID:15741437 PMID:19096003 PMID:18312481 More... RGD:4144814, RGD:4144815, RGD:4144228, RGD:4144208, RGD:4144813 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
JBrowse link
G Cd1d1 CD1d1 antigen susceptibility IMP associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748
JBrowse link
G Cd209a CD209a antigen ISO RGD PMID:21471959 RGD:5131188 NCBI chr 8:3,793,395...3,798,984
Ensembl chr 8:3,793,397...3,798,984
JBrowse link
G Cd274 CD274 antigen treatment IMP associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd28 CD28 antigen ISO RGD PMID:21356099 RGD:5131612 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd40 CD40 antigen treatment ISO
ISS
IEP
OMIM:600807 MouseDO
RGD
PMID:19220210 PMID:20205594 PMID:19159017 PMID:20941750 RGD:5132272, RGD:8547792, RGD:4144188, RGD:4892277 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd40lg CD40 ligand severity IMP RGD PMID:9502776 RGD:11352238 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd80 CD80 antigen IEP RGD PMID:21051864 PMID:21440530 PMID:21352203 RGD:5132621, RGD:5132619, RGD:5132620 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
JBrowse link
G Cd86 CD86 antigen treatment IEP
ISS
IMP
ISO
protein:increased expression:lung, alveolar macrophage (mouse)
OMIM:600807
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)
MouseDO
RGD
PMID:20941750 PMID:25344652 PMID:9449507 PMID:20668438 PMID:9551945 More... RGD:4892277, RGD:11354965, RGD:4892555, RGD:4892199, RGD:4892202, RGD:4892280 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cdh1 cadherin 1 ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:21540309 RGD:5132878 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdhr3 cadherin-related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr12:33,083,781...33,142,900
Ensembl chr12:33,083,795...33,142,874
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator susceptibility ISO
ISS
DNA:deletion: :p.F508del(human)
OMIM:600807
MouseDO
RGD
PMID:20298391 RGD:4140387 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Chat choline acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946
JBrowse link
G Chia1 chitinase, acidic 1 no_association ISO
ISS
IMP
IEP
DNA:snps:5' utr, cds:multiple (human)
OMIM:600807
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
mRNA:increased expression:lung (mouse)
MouseDO
RGD
PMID:16179638 PMID:20226308 PMID:19548841 PMID:15192232 PMID:14734765 RGD:4996473, RGD:5024922, RGD:5024921, RGD:4985150, RGD:4990463 NCBI chr 3:106,020,698...106,039,434
Ensembl chr 3:106,020,545...106,039,436
JBrowse link
G Chil1 chitinase-like 1 susceptibility ISO human gene in mouse model
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7
DNA:snp:5' utr:g.-131C>G rs4950928 (human)
protein:increased secretion:serum (human)
CTD
OMIM
ClinVar
RGD
PMID:18403759 PMID:19414556 PMID:19568425 PMID:18003958 RGD:4892663, RGD:4892630, RGD:4892632 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919
JBrowse link
G Chml choroideremia-like ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:18343558 RGD:5133238 NCBI chr 1:175,509,803...175,515,919
Ensembl chr 1:175,509,803...175,520,467
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:16931638 RGD:5133416 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac ISO
ISS
DNA:SNP: :rs6962027 (human)
OMIM:600807
MouseDO
RGD
PMID:19308904 RGD:5509586 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac severity ISO
IMP
RGD PMID:20394512 PMID:18348887 RGD:5133437, RGD:5133438 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IMP RGD PMID:21496385 RGD:5133703 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Clca1 chloride channel accessory 1 susceptibility IMP
ISS
ISO
OMIM:600807
DNA:SNPs (human)
MouseDO
RGD
PMID:11296262 PMID:17898169 PMID:15318163 RGD:4145661, RGD:4145653, RGD:4145656 NCBI chr 3:144,710,298...144,738,537
Ensembl chr 3:144,709,578...144,738,537
JBrowse link
G Cldn18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr 9:99,572,849...99,599,320
Ensembl chr 9:99,571,514...99,599,320
JBrowse link
G Cma1 chymase 1, mast cell severity
susceptibility
no_association
ISO
ISS
protein:increased expression:lung epithelium, mast cell (human)
OMIM:600807
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
MouseDO
RGD
PMID:20813890 PMID:15924217 PMID:15248847 RGD:5128804, RGD:1625396, RGD:1625397 NCBI chr14:56,178,908...56,182,132
Ensembl chr14:56,178,908...56,182,132
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO
ISS
DNA:SNP: :RS242941 (human)
OMIM:600807
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
MouseDO
RGD
PMID:19663668 PMID:16113459 RGD:5147485, RGD:5147488 NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO
ISS
DNA:SNPs: :multiple (human)
OMIM:600807
MouseDO
RGD
PMID:18408560 RGD:5130938 NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001
JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) severity IEP
IMP
ISO
protein:increased expression:lung
protein:increased expression:sputum
RGD PMID:20405019 PMID:9717963 PMID:19213775 RGD:5131473, RGD:10449521, RGD:5131476 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) ISO RGD PMID:17145927 RGD:1601020 NCBI chr15:78,210,000...78,235,201
Ensembl chr15:78,209,952...78,238,047
JBrowse link
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) ISO RGD PMID:17145927 RGD:1601020 NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) IEP
ISS
ISO
protein:increased expression:lung
OMIM:600807
MouseDO
RGD
PMID:20405019 PMID:21396376 RGD:5131473, RGD:5133731 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 severity
treatment
no_association
ISO
IDA
IMP
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNP: :rs3087243 (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
CTD
RGD
PMID:28807506 PMID:15871446 PMID:11726402 PMID:15316504 PMID:19895365 More... RGD:4891529, RGD:11344922, RGD:4891519, RGD:4891526, RGD:4891510, RGD:4891521, RGD:4891522, RGD:4891514, RGD:4891528, RGD:4891517, RGD:4891516, RGD:4891527 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Ctnna3 catenin (cadherin associated protein), alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr10:63,265,877...64,841,174
Ensembl chr10:63,265,877...64,839,446
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 no_association IMP
ISS
ISO
OMIM:600807
DNA:SNPs: :p.V249I, rs2669849 (human)
DNA:polymorphisms: :p.V249I, p.T280M (human)
MouseDO
RGD
PMID:21037587 PMID:17082760 PMID:17505143 RGD:4891882, RGD:4891895, RGD:4891904 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 ISO
IMP
protein:decreased expression:plasma RGD PMID:17302903 PMID:16602032 PMID:11994485 RGD:5135439, RGD:5135457, RGD:5135452 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl14 chemokine (C-X-C motif) ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 IEP mRNA:increased expression:lung RGD PMID:20045013 RGD:5129686 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 severity ISO RGD PMID:20371397 RGD:5134983 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Cxcl5 chemokine (C-X-C motif) ligand 5 ISO
IEP
mRNA:increased expression:bronchus epithelium RGD PMID:17234659 PMID:9620668 RGD:5135243, RGD:5135265 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 IMP RGD PMID:15210824 RGD:5135447 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 susceptibility
severity
IEP
ISS
ISO
OMIM:600807
DNA:SNP:intron:IVS1+234G>A (human)
protein:decreased expression:respiratory system fluid/secretion, T cell
MouseDO
RGD
PMID:18094012 PMID:16043121 PMID:16548899 PMID:17641057 RGD:4892088, RGD:5143934, RGD:5143932, RGD:5135484 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide susceptibility ISO
ISS
DNA:polymorphism: :-930A>G (human)
OMIM:600807
DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
MouseDO
RGD
PMID:19459419 PMID:18716406 RGD:4311041, RGD:4772770 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 ISS OMIM:600807 MouseDO NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP
mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:28807506 PMID:20514434 PMID:17081494 RGD:4892076, RGD:4892220 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 no_association
severity
ISO
ISS
IMP
DNA:SNPs:promoter, exon:multiple (human)
OMIM:600807
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNP: :927T>C (human)
mRNA, protein:increased expression:respiratory system mucosa
MouseDO
RGD
PMID:16771777 PMID:16630147 PMID:16776674 PMID:8087328 PMID:11591188 More... RGD:4889116, RGD:4784257, RGD:4782072, RGD:4888514, RGD:4848936, RGD:4781742, RGD:4781449, RGD:4843543, RGD:4847129 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO
ISS
DNA:polymorphism: :601A>G (human)
OMIM:600807
DNA:polymorphism: :-1220A>C (human)
MouseDO
RGD
PMID:15475736 PMID:15454733 RGD:5144002, RGD:5144003 NCBI chr14:73,263,515...73,286,554
Ensembl chr14:73,263,043...73,286,554
JBrowse link
G Dcn decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
JBrowse link
G Defb1 defensin beta 1 susceptibility ISO
ISS
DNA:SNP: :-1816 T>C (human)
OMIM:600807
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
MouseDO
RGD
PMID:15696078 PMID:16435024 RGD:4892263, RGD:4892254 NCBI chr 8:22,266,571...22,285,201
Ensembl chr 8:22,266,615...22,285,201
JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr15:28,155,000...28,472,191
Ensembl chr15:28,203,898...28,472,198
JBrowse link
G Dnmt1 DNA methyltransferase (cytosine-5) 1 IEP
ISO
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:23423710 PMID:23196709 RGD:9588646 NCBI chr 9:20,818,501...20,871,184
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dpp10 dipeptidylpeptidase 10 ISO
ISS
DNA:SNPs (human)
OMIM:600807
DNA:SNP:exon (human)
protein:increased expression:bronchus
DNA:SNP: :rs10208402 (human)
MouseDO
RGD
PMID:21103062 PMID:15118671 PMID:14566338 PMID:17967935 PMID:19672052 RGD:4889866, RGD:1331525, RGD:4892276, RGD:4892278, RGD:4892275 NCBI chr 1:123,259,867...124,773,809
Ensembl chr 1:123,249,200...124,773,776
JBrowse link
G Ear1 eosinophil-associated, ribonuclease A family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8874658 PMID:12153692 PMID:12587966 NCBI chr14:44,056,222...44,057,096
Ensembl chr14:44,056,222...44,112,974
JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 IMP RGD PMID:21255010 RGD:5128488 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022
JBrowse link
G Edn1 endothelin 1 ISO DNA:transition:intron:g.4124T>C (human)
CTD Direct Evidence: marker/mechanism
Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD
RGD
PMID:16981460 PMID:11668616 PMID:20588001 RGD:4144869, RGD:4144895 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:18632188 PMID:17448648 RGD:4892288, RGD:4892322 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
JBrowse link
G Ednrb endothelin receptor type B IMP
ISS
ISO
OMIM:600807
DNA:polymorphism (human)
mRNA:increased expression:bronchus, smooth muscle cell
MouseDO
RGD
PMID:18632188 PMID:17470272 PMID:15245576 RGD:4892288, RGD:4892321, RGD:4892324 NCBI chr14:104,052,051...104,083,248
Ensembl chr14:104,052,061...104,081,838
JBrowse link
G Egfr epidermal growth factor receptor severity IMP
ISO
IEP
protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (mouse)
protein:increased expression:lung epithelium (rat)
RGD PMID:21224214 PMID:12580917 PMID:21072743 PMID:19954006 RGD:5131633, RGD:5131468, RGD:5131642, RGD:5131870 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 IMP
ISS
ISO
OMIM:600807
mRNA:increased expression:bronchoalveolar lavage cell (human)
DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
MouseDO
RGD
PMID:11254538 PMID:18774390 PMID:18507785 RGD:5131985, RGD:5130915, RGD:5131993 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Elp1 elongator complex protein 1 no_association ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:11281413 PMID:12774215 RGD:5129157, RGD:5129158 NCBI chr 4:56,746,547...56,802,565
Ensembl chr 4:56,749,680...56,802,331
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal susceptibility ISO
ISS
DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human)
OMIM:600807
MouseDO
RGD
PMID:17711870 RGD:4889407 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Epx eosinophil peroxidase severity
disease_progression
ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:26645423 PMID:12199967 PMID:20813885 RGD:11574908, RGD:13506892, RGD:13506891 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362
JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus
RGD PMID:21658190 PMID:21711961 RGD:5147753, RGD:5147783 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2rl1 coagulation factor II (thrombin) receptor-like 1 ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:19864598 RGD:4892589 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735
JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide severity ISO Asthma symptoms persistent despite steroids in humans
Fatal asthma subjects
RGD PMID:20937062 PMID:21388666 RGD:5128717, RGD:5128711 NCBI chr 1:173,048,836...173,054,799
Ensembl chr 1:173,048,851...173,054,781
JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb IMP RGD PMID:20179765 RGD:11344929 NCBI chr 1:170,788,127...170,803,691
Ensembl chr 1:170,786,186...170,804,116
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV susceptibility ISO
ISS
DNA:polymorphism:exon:p.F158V(rs396991)(human)
OMIM:600807
MouseDO
RGD
PMID:18199088 RGD:5508449 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Fga fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fkbp5 FK506 binding protein 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G Foxp3 forkhead box P3 treatment ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27965764 PMID:29317916 PMID:28944907 PMID:27633092 RGD:38549365, RGD:38548920 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Gata3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802, RGD:5128803 NCBI chr 2:9,861,889...9,892,762
Ensembl chr 2:9,861,889...9,894,845
JBrowse link
G Gc vitamin D binding protein IMP
ISO
protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 PMID:21169467 RGD:5509920, RGD:5509920 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757
JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) susceptibility ISO DNA:polymorphism:promoter: -69C>T (human) RGD PMID:20374258 RGD:5490988 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 resistance
susceptibility
ISO DNA:deletion: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16870661 PMID:18988661 PMID:17651144 PMID:21051083 PMID:11075422 RGD:4142509, RGD:5490962, RGD:4140921 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm3 glutathione S-transferase, mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135039, RGD:5135038 NCBI chr 3:107,871,012...107,876,490
Ensembl chr 3:107,871,012...107,876,599
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 ISS OMIM:600807 MouseDO NCBI chr 3:107,803,170...107,806,001
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Gsto2 glutathione S-transferase omega 2 susceptibility ISO
ISS
DNA:polymorphism:exon:p. N142D (human)
OMIM:600807
MouseDO
RGD
PMID:20374258 RGD:5490988 NCBI chr19:47,853,879...47,874,747
Ensembl chr19:47,853,973...47,874,763
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 severity
susceptibility
disease_progression
no_association
ISO
IAGP
DNA:polymorphism:exon:p.I105V (rs1695) (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:SNPs: :p.I105V, p.A114V (human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNP: :p.A114V (human)
CTD
RGD
PMID:11994713 PMID:16870661 PMID:18988661 PMID:24117884 PMID:29411558 More... RGD:4142526, RGD:5490999, RGD:5490991, RGD:5490985, RGD:4140951, RGD:4142519, RGD:4140947, RGD:4140946 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 susceptibility ISO
ISS
OMIM:600807
DNA:deletion: :
MouseDO
RGD
PMID:15300848 PMID:21051083 PMID:11075422 RGD:4142539, RGD:5490962, RGD:4140921 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha ISO DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:10792356 PMID:12890388 PMID:10051703 PMID:11802952 PMID:19052351 RGD:5147799, RGD:1331670, RGD:5147831, RGD:5147617 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility
disease_progression
no_association
ISO Alternaria sensitive asthma
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
CTD
RGD
PMID:10792356 PMID:20298583 PMID:20159242 PMID:20214848 PMID:23331206 More... RGD:4144113, RGD:13506913, RGD:4144181, RGD:13506906, RGD:5147831, RGD:5147799, RGD:5147617 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha susceptibility ISO
ISS
DNA:polymorphisms: :
OMIM:600807
MouseDO
RGD
PMID:20159242 RGD:13506913 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,561,907...34,563,618
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility
no_association
severity
ISO DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:16792590 PMID:19528258 PMID:20159242 PMID:23331206 PMID:10051703 More... RGD:4144196, RGD:13506913, RGD:13506906, RGD:1331670, RGD:5147663, RGD:5147607, RGD:4144181 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 susceptibility ISO
ISS
DNA:polymorphism:
OMIM:600807
MouseDO
RGD
PMID:28380482 RGD:13506910 NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD
PMID:15611928 RGD:5144118 NCBI chr17:37,581,094...37,585,376
Ensembl chr17:37,581,111...37,585,375
JBrowse link
G H2-Pa histocompatibility 2, P region alpha locus susceptibility ISO
ISS
DNA:polymorphism: :
OMIM:600807
MouseDO
RGD
PMID:21814517 RGD:13506911 NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 IMP RGD PMID:17517968 RGD:5135525 NCBI chr11:46,345,758...46,372,082
Ensembl chr11:46,345,762...46,372,082
JBrowse link
G Hc hemolytic complement severity IEP
ISS
ISO
IAGP
mRNA:decreased expression:lung
OMIM:600807
MouseDO
RGD
PMID:10973279 PMID:15278436 PMID:20143644 PMID:11591795 PMID:20802484 RGD:5130158, RGD:5129512, RGD:5129706, RGD:1600651, RGD:5129681 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
JBrowse link
G Hdc histidine decarboxylase ISO
ISS
associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human)
OMIM:600807
MouseDO
RGD
PMID:20608921 RGD:5128884 NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit treatment IEP RGD PMID:18160846 RGD:10402541 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:20084838 RGD:5508450 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 severity IDA
ISO
CTD Direct Evidence: marker/mechanism
mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD
RGD
PMID:18048809 PMID:20596599 PMID:16196283 RGD:4145403, RGD:4145408 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnmt histamine N-methyltransferase no_association
susceptibility
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
RGD
PMID:10752634 PMID:10803682 PMID:16205835 PMID:17651147 PMID:15693910 More... RGD:5128888, RGD:5128883, RGD:5128885, RGD:5128881, RGD:5128887 NCBI chr 2:23,892,923...23,939,756
Ensembl chr 2:23,892,922...23,939,406
JBrowse link
G Hp haptoglobin ISO RGD PMID:21471098 PMID:21169467 RGD:5144151, RGD:5509920 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO
IEP
protein:increased expression:lung, serum (rat)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:aorta (mouse)
protein:increased secretion:lung (human)
CTD
RGD
PMID:17014439 PMID:25003170 PMID:20953388 PMID:20400685 PMID:20205697 RGD:4145331, RGD:4145444, RGD:4145509 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ifng interferon gamma treatment
resistance
IDA
IMP
ISO
protein:increased expression:sputum RGD
GAD
PMID:19542437 PMID:12396623 PMID:15118671 PMID:20953328 PMID:20817868 RGD:5128479, RGD:10755706, RGD:1331525, RGD:4145525, RGD:4145651 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP
ISS
ISO
OMIM:600807
DNA: SNP: Leu467Pro
MouseDO
RGD
PMID:21737883 PMID:12851715 RGD:6480255, RGD:6480431 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Ifnl2 interferon lambda 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr 7:28,208,209...28,209,957
Ensembl chr 7:28,208,261...28,209,880
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857
JBrowse link
G Il10 interleukin 10 treatment
susceptibility
ISO
IMP
IEP
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :-627C>A (human)
protein:decreased expression:plasma
CTD
RGD
PMID:29317916 PMID:20560982 PMID:21998459 PMID:20237464 PMID:20644177 More... RGD:5131623, RGD:11046261, RGD:4140471, RGD:4140459, RGD:4143221, RGD:4140451, RGD:4140421 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12a interleukin 12a IMP RGD PMID:17056578 PMID:17548618 RGD:4438438, RGD:4373570 NCBI chr 3:68,597,977...68,605,883
Ensembl chr 3:68,597,977...68,605,880
JBrowse link
G Il12b interleukin 12b severity
susceptibility
ISO
ISS
DNA:polymorphisms:introns:
OMIM:600807
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphisms:promoter, 3'utr:
DNA:polymorphism:promoter
MouseDO
ClinVar
RGD
PMID:15322986 PMID:15322986 PMID:16210052 PMID:12241719 RGD:1600043, RGD:4145438, RGD:4145428 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il13 interleukin 13 susceptibility
severity
no_association
IMP
ISO
IDA
IEP
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Dermatitis, Atopic;DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
DNA:polymorphism: :-1512A>C, -1112C>T, 2044G>A (human)
mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid
protein:increased expression:serum
DNA:polymorphism:cds:p.R130Q (human)
DNA:polymorphisms:promoters,exon4: rs1881457, rs1800925, rs20541 (human)
DNA:polymorphism: :p. R110Q (human)
DNA:SNP: :c. -646A>G (human)
protein:increased expression:sputum
DNA:polymorphism: :c. 1923C>T (human)
DNA:polymorphism:promoter:c. -1055C>T (human)
DNA:polymorphisms: :rs20541, rs1295685(human)
DNA:polymorphism:3'utr:c.4738G>A (human)
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism: :c. 2044G>A (human)
ClinVar
OMIM
CTD
RGD
PMID:10699178 PMID:11588017 PMID:11709756 PMID:12847555 PMID:12928861 More... RGD:4206706, RGD:8549509, RGD:4892639, RGD:2301686, RGD:4145664, RGD:4145453, RGD:4145508, RGD:2307110, RGD:4763153, RGD:4763761, RGD:4145601, RGD:4145639, RGD:4321828, RGD:4146241, RGD:4145777, RGD:4145775, RGD:4220633, RGD:4145534, RGD:4765128, RGD:4145593, RGD:4145776 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 no_association IDA
ISS
ISO
IMP
IEP
OMIM:600807
DNA:polymorphism: :1398A>G (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
DNA:polymorphism: :1050C>T (human)
mRNA:increased expression:bronchus
MouseDO
RGD
PMID:11714828 PMID:17006604 PMID:17392323 PMID:10686479 PMID:18480254 More... RGD:4892654, RGD:4892639, RGD:4892650, RGD:4892655, RGD:4892647, RGD:4892646 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912
JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 IMP
ISO
IEP
protein:increased expression:serum
mRNA:increased expression:bronchus
RGD PMID:17885690 PMID:21462799 PMID:20383033 RGD:4892649, RGD:8549521, RGD:4892646 NCBI chr  X:146,166,474...146,214,982
Ensembl chr  X:146,166,472...146,212,188
JBrowse link
G Il15 interleukin 15 no_association IMP
ISS
ISO
OMIM:600807
DNA:SNPs: :multiple (human)
MouseDO
RGD
PMID:15843549 PMID:16629787 PMID:11160248 PMID:15131572 PMID:19133918 RGD:5000757, RGD:4984421, RGD:4990462, RGD:5000758, RGD:5000760 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
JBrowse link
G Il16 interleukin 16 no_association
severity
IMP
ISS
ISO
OMIM:600807
DNA:SNP:promoter:-295T>C (human)
protein:increased expression:serum
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
MouseDO
RGD
PMID:10585533 PMID:15784111 PMID:16387589 PMID:12872394 PMID:16734115 RGD:5024937, RGD:5024935, RGD:5024934, RGD:5024930, RGD:5024928 NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934
JBrowse link
G Il17a interleukin 17A susceptibility ISO
ISS
IMP
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
OMIM:600807
protein:increased expression:sputum
protein:increased expression:alveolar macrophage
DNA:SNP:promoter:rs2275913 (human)
MouseDO
RGD
PMID:18060619 PMID:20351038 PMID:15730730 PMID:18941201 PMID:20437253 RGD:4839043, RGD:4888527, RGD:4889114, RGD:4889152, RGD:4889139 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il17rb interleukin 17 receptor B IMP associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr14:29,718,125...29,730,853
Ensembl chr14:29,718,092...29,730,853
JBrowse link
G Il18 interleukin 18 severity
susceptibility
disease_progression
ISO
ISS
IMP
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
OMIM:600807
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
protein:increased expression:serum
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:polymorphism: :c. -105A>C (human)
MouseDO
RGD
PMID:17767553 PMID:20497957 PMID:16433859 PMID:18826499 PMID:11174201 More... RGD:4889585, RGD:4889898, RGD:4889923, RGD:4889908, RGD:4889863, RGD:4889898, RGD:4889900, RGD:4889910 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il18r1 interleukin 18 receptor 1 ISO
ISS
IEP
OMIM:600807
DNA:SNP: :rs3771166 (human)
DNA:SNPs: :multiple (human)
MouseDO
RGD
PMID:19910030 PMID:20860503 PMID:18382474 PMID:11972614 PMID:18774397 RGD:5024945, RGD:5024942, RGD:5024947, RGD:5024948, RGD:5024946 NCBI chr 1:40,504,712...40,540,014
Ensembl chr 1:40,504,712...40,540,014
JBrowse link
G Il19 interleukin 19 IEP mRNA, protein:increased expression:lung, serum RGD PMID:15557163 RGD:5037236 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852
JBrowse link
G Il1a interleukin 1 alpha ISO
ISS
DNA:polymorphisms: :
OMIM:600807
MouseDO
RGD
PMID:18763028 RGD:4142802 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta susceptibility IDA
ISO
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil
DNA:polymorphism: :-511C>T (human)
CTD
RGD
PMID:9176529 PMID:19684087 PMID:19842845 PMID:18926055 RGD:4142836, RGD:4142830, RGD:4142864 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 susceptibility
severity
IEP
ISO
IMP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1420101 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1041973 (human)
CTD
RGD
PMID:19198610 PMID:21150878 PMID:21804549 PMID:24241537 PMID:27472835 More... RGD:5144235, RGD:5144245, RGD:5144244, RGD:5144243, RGD:5144242, RGD:5144240, RGD:5144239, RGD:5144237 NCBI chr 1:40,444,025...40,504,578
Ensembl chr 1:40,468,730...40,504,575
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
severity
ISO DNA:SNP: :rs2234678 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNPs: :rs447713, rs3087271 (human)
protein:increased expression:plasma
DNA, protein:repeat, decreased expression (human)
DNA:polymorphism:intron (human)
CTD
RGD
PMID:9176529 PMID:17107994 PMID:15020290 PMID:16409203 PMID:16724092 More... RGD:4143208, RGD:4143216, RGD:4143163, RGD:4143209, RGD:4143225, RGD:4143224, RGD:4142864, RGD:4142802 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il2 interleukin 2 susceptibility ISO
ISS
OMIM:600807
DNA:SNP:promoter:rs2069762(human)
MouseDO
RGD
PMID:20926789 PMID:16333313 RGD:4889118, RGD:8663473 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il21 interleukin 21 ISO
ISS
DNA:SNP:exon:5250C>T (human)
OMIM:600807
MouseDO
RGD
PMID:18802358 RGD:5147396 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785
JBrowse link
G Il22 interleukin 22 treatment
severity
IMP
ISO
mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum
RGD PMID:21789181 PMID:21998459 PMID:21535180 PMID:21297073 RGD:5147401, RGD:11046261, RGD:5147409, RGD:5147403 NCBI chr10:118,040,456...118,045,952
Ensembl chr10:118,040,847...118,045,952
JBrowse link
G Il22b interleukin 22B severity ISO protein:increased expression:serum
mRNA:increased expression:blood, mononuclear cell
RGD PMID:21297073 PMID:21535180 RGD:5147403 RGD:5147409 NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943
JBrowse link
G Il23r interleukin 23 receptor IMP RGD PMID:19935773 RGD:5037240 NCBI chr 6:67,399,916...67,468,839
Ensembl chr 6:67,399,916...67,468,839
JBrowse link
G Il25 interleukin 25 IEP mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294
JBrowse link
G Il27 interleukin 27 treatment
susceptibility
IDA
ISS
IMP
ISO
OMIM:600807
protein:increased expression:sputum
DNA:SNP: :g.-964A>G (human)
MouseDO
RGD
PMID:17878337 PMID:26595888 PMID:20817868 PMID:17318299 PMID:19542437 RGD:5128491, RGD:11076728, RGD:4145651, RGD:5128485, RGD:5128479 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113
JBrowse link
G Il27ra interleukin 27 receptor, alpha IMP RGD PMID:16081811 RGD:5128496 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IMP RGD PMID:21377197 PMID:20525707 RGD:5147437, RGD:5147445 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004
JBrowse link
G Il2rb interleukin 2 receptor, beta chain ISO
ISS
IMP
DNA:SNP: :rs2284033 (human)
OMIM:600807
MouseDO
RGD
PMID:20860503 PMID:18641329 RGD:5024942, RGD:5147447 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471
JBrowse link
G Il3 interleukin 3 susceptibility ISO
ISS
DNA:SNP: :rs40401(human)
OMIM:600807
DNA:polymorphism:cds:+79T>C(S27P)(human)
MouseDO
RGD
PMID:24684517 PMID:15372320 RGD:13506914, RGD:13506916 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
JBrowse link
G Il33 interleukin 33 treatment
severity
ISO
IMP
CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease
CTD
RGD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:27472835 PMID:29067999 More... RGD:39939002, RGD:39938968 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Il4 interleukin 4 treatment
no_association
IMP
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:lung
DNA:SNP: :589C>T (human)
DNA:polymorphism (human)
mRNA:increased expression:lung, spleen
protein:increased expression:respiratory system fluid/secretion
CTD
RGD
PMID:18357729 PMID:21375458 PMID:24946644 PMID:24450480 PMID:18211752 More... RGD:5128557, RGD:10402799, RGD:10402791, RGD:2317290, RGD:5128560, RGD:4889866, RGD:5128500, RGD:5128502 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il4ra interleukin 4 receptor, alpha susceptibility
severity
disease_progression
ISO
ISS
IEA
IMP
DNA:polymorphism:cds:p.Q551R (human)
OMIM:600807
DNA:polymorphism:cds:p.I50V (human)
DNA:polymorphism::-1902G/A (human)
DNA:SNPs: :multiple
DNA:SNPs:cds:p. I75V, Q576R (human)
protein:increased secretion:plasma|DNA:polymorphism:promoter:c.-3223C>T (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism:cds:p.Q576R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:mutation:cds:p.Q576R (mouse)
MouseDO
RGD
PMID:17586032 PMID:18425216 PMID:20868478 PMID:17823973 PMID:11398072 More... RGD:4890348, RGD:4890346, RGD:4890387, RGD:4890347, RGD:4890406, RGD:4890404, RGD:4890351, RGD:4890349, RGD:4890402, RGD:4890024, RGD:5128514, RGD:5128553, RGD:4890003, RGD:4890352 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Il5 interleukin 5 treatment
disease_progression
IEP
ISO
IMP
protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
protein:increased expression:lungs, respiratory system fluid/secretion
protein: increased levels: sputum
DNA:polymorphism:promoter:-703C>T (human)
CTD
RGD
PMID:7540862 PMID:23266719 PMID:15626484 PMID:25008888 PMID:11159041 More... RGD:4890947, RGD:11354973, RGD:5687189, RGD:5687144, RGD:5687140, RGD:4890948, RGD:4890963, RGD:4145461, RGD:4890962, RGD:4890940, RGD:4890938 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il5ra interleukin 5 receptor, alpha IMP
ISS
ISO
OMIM:600807
DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)
MouseDO
RGD
PMID:10848907 PMID:20592918 PMID:17276963 PMID:10224351 PMID:16217591 More... RGD:5128627, RGD:5128614, RGD:5128617, RGD:5128623, RGD:5128626, RGD:5128625 NCBI chr 6:106,687,336...106,725,998
Ensembl chr 6:106,687,318...106,725,998
JBrowse link
G Il6 interleukin 6 IDA
ISO
CTD Direct Evidence: marker/mechanism
associated with Hypersensitivity;protein:increased expression:sputum
protein:increased expression:lung
CTD
RGD
PMID:29902480 PMID:21115736 PMID:20840469 PMID:20816188 PMID:20658762 RGD:5128630, RGD:4143265, RGD:4143266, RGD:4143271 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6ra interleukin 6 receptor, alpha IMP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29902480 PMID:17496315 PMID:21115736 RGD:5128662, RGD:5128630 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
JBrowse link
G Il9 interleukin 9 ISO
ISS
IMP
IEP
OMIM:600807
protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm
MouseDO
RGD
PMID:21356110 PMID:17446528 PMID:15531759 PMID:15303135 PMID:12153980 RGD:5128707, RGD:5128686, RGD:5128690, RGD:5128691, RGD:5128700 NCBI chr13:56,627,090...56,630,070
Ensembl chr13:56,627,090...56,630,059
JBrowse link
G Il9r interleukin 9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chr11:32,137,544...32,155,283
Ensembl chr11:32,137,541...32,150,279
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:17503328 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035
JBrowse link
G Irf1 interferon regulatory factor 1 no_association
susceptibility
ISO
ISS
DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
OMIM:600807
DNA:repeat:intron (human)
protein:increased expression:respiratory tract epithelium
MouseDO
RGD
PMID:11069564 PMID:16961714 PMID:10225979 RGD:5128726, RGD:5128724, RGD:5128723 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Irf3 interferon regulatory factor 3 IMP RGD PMID:20673978 RGD:5128793 NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272
JBrowse link
G Itgb3 integrin beta 3 ISO
ISS
DNA:SNPs: :
OMIM:600807
MouseDO
RGD
PMID:17556058 RGD:5037230 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Itgb6 integrin beta 6 IEA OMIM:600807 MouseDO NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070
JBrowse link
G Kdr kinase insert domain protein receptor IMP
ISO
associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:20921519 PMID:17651148 RGD:5684385, RGD:8551771 NCBI chr 5:76,093,487...76,139,885
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kif3a kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr11:53,456,531...53,495,075
Ensembl chr11:53,458,206...53,492,794
JBrowse link
G Krt19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
JBrowse link
G Lep leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 treatment ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:16424226 RGD:9685213 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lta lymphotoxin A susceptibility
no_association
ISO
ISS
DNA:polymorphisms:promoter
OMIM:600807
DNA:polymorphism:intron
MouseDO
RGD
PMID:15969671 PMID:18947013 PMID:17536219 PMID:12530118 RGD:4143373, RGD:4143370, RGD:4143371, RGD:4143254 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327
JBrowse link
G Lta4h leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr10:93,289,258...93,320,758
Ensembl chr10:93,289,273...93,320,737
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO
ISS
associated with Bronchiolitis;DNA:polymorphism:exon:
OMIM:600807
DNA:SNP:cds:p.G54D(human)
MouseDO
RGD
PMID:22512728 PMID:22674410 RGD:8693709, RGD:12910828 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G Mefv Mediterranean fever susceptibility ISO
ISS
DNA:mutations:exons
OMIM:600807
MouseDO
RGD
PMID:18219832 RGD:5129186 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) severity ISO
ISS
IMP
protein:increased expression:bronchoalveolar lavage fluid
OMIM:600807
DNA:SNP:promoter:rs755622(human)
DNA:repeats:promoter
MouseDO
RGD
PMID:9637721 PMID:19317738 PMID:17373669 PMID:16186482 PMID:16455830 RGD:4891043, RGD:4891059, RGD:4891035, RGD:4891052, RGD:1641985 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
DNA:SNP: : rs2664538(human)
mRNA, protein:increased expression:lung
CTD
RGD
PMID:11742282 PMID:15131573 PMID:21439806 PMID:19361849 PMID:20181264 More... RGD:5129204, RGD:5129687, RGD:5130859, RGD:2325953, RGD:5129522 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase susceptibility ISO
ISS
DNA:polymorphism: :−463G > A (human)
OMIM:600807
protein:increased expression:serum
MouseDO
RGD
PMID:19544176 PMID:10731862 RGD:5130989, RGD:5130994 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 susceptibility ISO
ISS
DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
OMIM:600807
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
DNA:SNP: : -109C>T (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050
MouseDO
RGD
PMID:19218813 PMID:21320344 PMID:19862939 PMID:8817330 RGD:5131151, RGD:5131149, RGD:5131092, RGD:1599903 NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO
ISS
DNA:transition:cds:g.677C>T (human)
OMIM:600807
MouseDO
RGD
PMID:20456312 RGD:4891145 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Muc1 mucin 1, transmembrane ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc2 mucin 2 ISO
ISS
IEP
associated with hypersensitivity
OMIM:600807
MouseDO
RGD
PMID:11062147 PMID:14594655 RGD:5131178, RGD:7349354 NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric treatment ISO
IDA
IEP
protein:increased expression:lung
mRNA, protein:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:17698377 PMID:21549818 PMID:21780541 PMID:14594655 PMID:17590487 RGD:5131204, RGD:7364729, RGD:7349407, RGD:7349354, RGD:2324962 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Muc5b mucin 5, subtype B, tracheobronchial ISO
IEP
protein:altered expression:sputum RGD PMID:11802783 PMID:11587997 RGD:5131252, RGD:7364763 NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821
JBrowse link
G Myb myeloblastosis oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 ameliorates IMP RGD PMID:26882889 RGD:11531666 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Mylk myosin, light polypeptide kinase ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:17472811 RGD:4891492 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) susceptibility ISO
ISS
DNA:polymorphisms: :
OMIM:600807
Asthma, Aspirin-Induced; DNA:polymorphism: :
MouseDO
RGD
PMID:16924569 PMID:20602614 RGD:5131606, RGD:5131600 NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr 2:75,505,857...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Ngf nerve growth factor severity ISO
ISS
IEP
protein:increased expression:blood, eosinophil
OMIM:600807
protein:increased expression:lung, serum
MouseDO
RGD
PMID:12752594 PMID:17164945 PMID:11737043 PMID:17497413 RGD:4891122, RGD:4891108, RGD:4891123, RGD:4891068 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) IMP RGD PMID:16603479 PMID:12540484 RGD:5144070, RGD:5144072 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 susceptibility ISO
ISS
DNA:SNP: :rs2075817 (human)
OMIM:600807
DNA:insertion:cds:
MouseDO
RGD
PMID:16918516 PMID:15718249 RGD:5131519, RGD:5131518 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO
ISS
IDA
DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human)
OMIM:600807
MouseDO
RGD
PMID:16008671 PMID:21051079 RGD:5131477, RGD:5508757 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal susceptibility ISO
ISS
DNA:repeats:exon
OMIM:600807
DNA:repeats:intron
DNA:repeats: :
MouseDO
RGD
PMID:10833424 PMID:14767694 PMID:10673365 PMID:20609134 RGD:5132860, RGD:5132615, RGD:5132869, RGD:5132863 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Nos2 nitric oxide synthase 2, inducible severity
disease_progression
no_association
IMP
ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:lung (rat)
DNA:repeats:promoter
protein:increased expression:lung, bronchoalveolar lavage fluid
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:repeats:promoter, introns (human)
DNA:SNP:exon:p.S608L (human)
mRNA:increased expression:monocyte
DNA:repeat:promoter
CTD
RGD
PMID:19800904 PMID:20841959 PMID:21847581 PMID:18714530 PMID:17161822 More... RGD:4891480, RGD:5509073, RGD:4891508, RGD:4891927, RGD:4891910, RGD:4891924, RGD:4891925, RGD:4891419, RGD:4891957, RGD:4891953 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell susceptibility ISO
ISS
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
OMIM:600807
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:repeats:intron
MouseDO
RGD
PMID:18486767 PMID:16837812 PMID:16081038 RGD:4892053, RGD:4892058, RGD:4892062 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Npsr1 neuropeptide S receptor 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2
CTD
OMIM
ClinVar
RGD
PMID:15073379 PMID:15710598 PMID:15764725 PMID:16926187 PMID:15073379 More... RGD:4891921, RGD:4891922, RGD:4891923 NCBI chr 9:24,009,212...24,229,151
Ensembl chr 9:24,009,292...24,227,694
JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 susceptibility ISO DNA:SNP:exon:c. 609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c.609C>T (human)
CTD
RGD
PMID:20049212 PMID:19027876 PMID:19591959 RGD:5135006, RGD:5135005 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment
susceptibility
severity
ISO
ISS
OMIM:600807
DNA:polymorphism:intron
protein:increased expression, decreased activity:leukocyte, mononuclear
MouseDO
RGD
PMID:18396779 PMID:20727335 PMID:21113676 PMID:18799869 PMID:15295049 RGD:4892328, RGD:7174728, RGD:4892568, RGD:4892594, RGD:4892609 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Ntf3 neurotrophin 3 IEP
ISS
ISO
protein:increased expression:lung, serum
OMIM:600807
MouseDO
RGD
PMID:17497413 PMID:11737043 RGD:4891068, RGD:4891123 NCBI chr 6:126,078,375...126,143,734
Ensembl chr 6:126,078,375...126,143,873
JBrowse link
G Ntf5 neurotrophin 5 IEP protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr 7:45,063,119...45,066,603
Ensembl chr 7:45,063,119...45,066,603
JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 IMP
ISO
mRNA:increased expression:lung: RGD PMID:20934630 PMID:16708804 RGD:5684766, RGD:5684772 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
JBrowse link
G Ormdl3 ORM1-like 3 (S. cerevisiae) ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr11:98,472,120...98,478,071
Ensembl chr11:98,472,082...98,478,194
JBrowse link
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 ISO
ISS
IMP
OMIM:600807 MouseDO
RGD
PMID:22010907 PMID:19822647 RGD:6480532, RGD:6480533 NCBI chr 3:59,123,692...59,170,408
Ensembl chr 3:59,123,693...59,170,292
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 treatment IMP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell
CTD
RGD
PMID:18261157 PMID:12594058 PMID:26205779 PMID:26205779 RGD:5683910, RGD:11073727, RGD:11073727 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pdcd1 programmed cell death 1 treatment IMP associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278
JBrowse link
G Pde4b phosphodiesterase 4B, cAMP specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 4:101,944,529...102,464,472
Ensembl chr 4:101,944,740...102,464,456
JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide IEP
ISO
protein: increased expression RGD PMID:21216974 PMID:21216974 RGD:6483071, RGD:6483071 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pgf placental growth factor IMP
ISS
OMIM:600807 MouseDO
RGD
PMID:22268141 RGD:6483605 NCBI chr12:85,213,411...85,224,559
Ensembl chr12:85,213,409...85,224,564
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IMP RGD PMID:18754810 RGD:6482695 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Pin1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:18188456 RGD:8693422 NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) ISO RGD PMID:15557087 RGD:1642462 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma and atopy, susceptibility to
OMIM
CTD
ClinVar
RGD
PMID:10733466 PMID:15115767 PMID:10733466 RGD:1581025 NCBI chr17:43,878,885...43,923,093
Ensembl chr17:43,878,989...43,923,092
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21912604 PMID:18519237 RGD:4892037 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
JBrowse link
G Prf1 perforin 1 (pore forming protein) IMP
ISO
RGD PMID:22250087 PMID:21426642 RGD:6482815, RGD:6482818 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Prg2 proteoglycan 2, bone marrow severity
disease_progression
no_association
ISO
IMP
mRNA:increased expression:eosinophil:
associated with cough;protein:increased expression:sputum:
associated with viral infection;mRNA:increased expression:sputum:
RGD PMID:16982448 PMID:22022864 PMID:24450586 PMID:11067904 RGD:13506941, RGD:13506944, RGD:13506943, RGD:13506942 NCBI chr 2:84,810,805...84,813,977
Ensembl chr 2:84,810,805...84,813,976
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link
G Prmt2 protein arginine N-methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr10:76,043,060...76,073,699
Ensembl chr10:76,043,056...76,073,699
JBrowse link
G Prmt3 protein arginine N-methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 7:49,428,067...49,508,016
Ensembl chr 7:49,428,094...49,508,013
JBrowse link
G Prmt5 protein arginine N-methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr14:54,744,639...54,754,927
Ensembl chr14:54,744,644...54,754,982
JBrowse link
G Proc protein C treatment ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:26381519 RGD:11099992 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623
JBrowse link
G Prol1 proline rich, lacrimal 1 susceptibility ISO ClinVar Annotator: match by term: Asthma, protection against
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:11378823 PMID:16759176 NCBI chr 5:88,465,171...88,476,676
Ensembl chr 5:88,465,171...88,476,673
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgdr prostaglandin D receptor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr14:45,088,692...45,096,832
Ensembl chr14:45,088,692...45,096,832
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 ISO
IMP
Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:27103662 PMID:19796209 PMID:19392992 PMID:18757520 RGD:5135020, RGD:5135019, RGD:5135018 NCBI chr19:10,901,883...10,919,875
Ensembl chr19:10,914,524...10,919,875
JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO
ISS
IEP
IMP
OMIM:600807
mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)
mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)
MouseDO
RGD
PMID:19862936 PMID:19878559 PMID:15316498 PMID:17573729 PMID:18097056 More... RGD:5135515, RGD:5135514, RGD:5143931, RGD:5143923, RGD:5135534, RGD:5135526, RGD:5135522 NCBI chr 1:149,975,782...149,983,985
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rad50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
JBrowse link
G Rhoa ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Runx1 runt related transcription factor 1 ISO DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Runx3 runt related transcription factor 3 IEA OMIM:600807 MouseDO NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 susceptibility ISO
ISS
mRNA,protein:decreased expression:bronchial alveolar lavage fluid, lung:
OMIM:600807
ClinVar Annotator: match by term: Asthma, susceptibility to
associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
protein:decreased expression:serum
MouseDO
ClinVar
RGD
PMID:9550363 PMID:9643286 PMID:12100044 PMID:12921604 PMID:21255142 More... RGD:5144052, RGD:5144226, RGD:5144148 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322
JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 susceptibility
severity
no_association
ISO
IEP
IDA
DNA:SNP:promoter:-112G>A (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma, susceptibility to
mRNA,protein:decreased expression:;lung
protein:increased expression:sputum
CTD
OMIM
ClinVar
RGD
PMID:11813133 PMID:11813133 PMID:15531759 PMID:16456148 PMID:17218572 More... RGD:5144229, RGD:5128690, RGD:5144233, RGD:5144232, RGD:5144231, RGD:5144230 NCBI chr18:43,897,346...43,900,464
Ensembl chr18:43,897,354...43,900,464
JBrowse link
G Sell selectin, lymphocyte IMP RGD PMID:21437035 PMID:21515793 RGD:5685685, RGD:5685696 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 severity
susceptibility
no_association
ISO
ISS
protein:increased expression:plasma
OMIM:600807
DNA:polymorphism:promoter:rs1799768 (human)
protein:increased activity, increased expression:plasma, lung
MouseDO
RGD
PMID:19703828 PMID:19063817 PMID:19604112 PMID:18594148 RGD:4144831, RGD:4144832, RGD:4144833, RGD:4144836 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Sftpa1 surfactant associated protein A1 ISO
IEP
protein:decreased expression:lung, Clara cell, pneumocyte
mRNA, protein:increased expression:lung
RGD PMID:15816355 PMID:16629790 PMID:18926058 PMID:18802356 RGD:4143398, RGD:4143462, RGD:4143289, RGD:4143516 NCBI chr14:40,853,745...40,858,330
Ensembl chr14:40,853,739...40,858,409
JBrowse link
G Sftpb surfactant associated protein B ISO
IEP
protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell
RGD PMID:16629790 PMID:11472974 PMID:15816355 PMID:18926058 RGD:4143462, RGD:4143465, RGD:4143398, RGD:4143289 NCBI chr 6:72,281,594...72,291,356
Ensembl chr 6:72,281,594...72,291,354
JBrowse link
G Sftpc surfactant associated protein C susceptibility ISO
ISS
IEP
DNA:polymorphism: :p.A53T (human)
OMIM:600807
protein:increased expression:lung
mRNA, protein:decreased expression:lung
MouseDO
RGD
PMID:19910179 PMID:16629790 PMID:11472974 RGD:4144063, RGD:4143462, RGD:4143465 NCBI chr14:70,758,381...70,761,521
Ensembl chr14:70,758,389...70,761,521
JBrowse link
G Sftpd surfactant associated protein D ISO
ISS
IEP
mRNA, protein:increased expression:lung
OMIM:600807
associated with Bronchitis;protein:increased expression:lung
MouseDO
RGD
PMID:18802356 PMID:11472974 PMID:18266831 PMID:16839409 PMID:16629790 RGD:4143516, RGD:4143465, RGD:4143517, RGD:4143508, RGD:4143462 NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 IAGP RGD PMID:12847242 RGD:5684966 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221
JBrowse link
G Slc18a3 solute carrier family 18 (vesicular monoamine), member 3 ISO RGD PMID:17328924 RGD:5686690 NCBI chr14:32,184,394...32,186,807
Ensembl chr14:32,184,395...32,186,807
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 ISO RGD PMID:17328924 RGD:5686690 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc5a7 solute carrier family 5 (choline transporter), member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr17:54,580,618...54,606,071
Ensembl chr17:54,580,618...54,606,062
JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 susceptibility ISO
ISS
DNA:repeat:intron (human)
OMIM:600807
MouseDO
RGD
PMID:19806585 RGD:4889460 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
JBrowse link
G Sod1 superoxide dismutase 1, soluble ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:15743779 RGD:1581231 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sprr2b small proline-rich protein 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 3:92,224,012...92,225,392
Ensembl chr 3:92,223,927...92,225,392
JBrowse link
G Stat4 signal transducer and activator of transcription 4 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28807506 PMID:18211752 RGD:2317290 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348
JBrowse link
G Stat6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:19087723 PMID:16083555 RGD:7244151, RGD:7244153 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Tac1 tachykinin 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tacr1 tachykinin receptor 1 ISO protein:increased expression:lung
mRNA:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:17392578 PMID:8240667 PMID:16409782 RGD:2304339, RGD:5147645, RGD:5147475 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085
JBrowse link
G Tacr2 tachykinin receptor 2 ISO
ISS
DNA:SNP:cds:p.G231E (human)
OMIM:600807
MouseDO
RGD
PMID:20175803 PMID:19880429 RGD:5147640, RGD:5147641 NCBI chr10:62,088,217...62,101,769
Ensembl chr10:62,088,217...62,101,769
JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) susceptibility ISO
ISS
DNA:polymorphism: :
OMIM:600807
MouseDO
RGD
PMID:12640628 RGD:5147845 NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199
JBrowse link
G Tbx21 T-box 21 ISO
IEA
CTD Direct Evidence: marker/mechanism
OMIM:600807
CTD
MouseDO
PMID:15806396 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
G Tbxa2r thromboxane A2 receptor susceptibility
severity
ISO
ISS
OMIM:600807
DNA:polymorphism:cds:924T>C(human)
MouseDO
RGD
PMID:15118671 PMID:12000493 PMID:15805995 RGD:1331525, RGD:11059535, RGD:11059534 NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006
JBrowse link
G Tgfb1 transforming growth factor, beta 1 no_association
onset
ISO
IMP
IEP
DNA:polymorphism: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:promoter, exon:multiple (human)
mRNA:increased expression:lung
protein:increased expression:serum
DNA:SNP:cds:915G>C (human)
DNA:polymorphisms: :multiple (human)
DNA:SNP: :-509C>T (human)
CTD
RGD
PMID:16365456 PMID:19138248 PMID:19222424 PMID:19620629 PMID:19096005 More... RGD:4145299, RGD:4145132, RGD:4145143, RGD:4145113, RGD:4145139, RGD:4145142, RGD:4145144, RGD:4145280, RGD:4145295, RGD:4143443, RGD:4145297 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Thbd thrombomodulin ISO
ISS
OMIM:600807 MouseDO
RGD
PMID:20709825 RGD:5684984 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370
JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO
ISS
DNA:SNP (human)
OMIM:600807
MouseDO
RGD
PMID:18547625 RGD:4889528 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906
JBrowse link
G Tlr2 toll-like receptor 2 susceptibility
severity
ISO
ISS
IEP
IMP
DNA:SNP: :596T>C (human)
OMIM:600807
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs3804100 (human)
DNA:SNP: :rs4696480 (human)
DNA:SNP: :rs7656411 (human)
MouseDO
RGD
PMID:19096003 PMID:22402138 PMID:19148143 PMID:20685742 PMID:20815312 More... RGD:4144228, RGD:7800732, RGD:2312679, RGD:4144171, RGD:4145352, RGD:4145343, RGD:4145334 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr3 toll-like receptor 3 no_association ISO
ISS
IMP
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
OMIM:600807
DNA:snp:cds:p.L412F (human)
MouseDO
RGD
PMID:21129050 PMID:14987294 PMID:21364926 PMID:17434873 PMID:17610940 RGD:5129226, RGD:5129493, RGD:5128500, RGD:5129478, RGD:5129475 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
JBrowse link
G Tlr4 toll-like receptor 4 susceptibility
no_association
severity
ISO
ISS
IDA
IMP
DNA:Polymorphism:cds:p.D299G (human)
OMIM:600807
DNA:SNPs: :rs10983755, rs1927914 (human)
DNA:SNPs::
protein:decreased expression:leukocytes, mononuclear
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
MouseDO
RGD
PMID:15356557 PMID:19159017 PMID:20628601 PMID:19330007 PMID:20685742 More... RGD:4144817, RGD:4144188, RGD:4144176, RGD:4144141, RGD:4144171, RGD:4144190, RGD:4144198 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tlr6 toll-like receptor 6 susceptibility ISO
ISS
DNA:SNP (human)
OMIM:600807
DNA:SNP: :p.S249P (human)
MouseDO
RGD
PMID:18547625 PMID:15266299 RGD:4889528, RGD:4889538 NCBI chr 5:65,109,379...65,128,387
Ensembl chr 5:65,109,374...65,117,440
JBrowse link
G Tlr9 toll-like receptor 9 no_association
susceptibility
severity
ISO
ISS
IMP
DNA:snp:promoter:g.-1237T>C rs5743836 (human)
OMIM:600807
protein:increased expression:peripheral blood mononuclear cell (human)
MouseDO
RGD
PMID:21324137 PMID:18312481 PMID:20016192 PMID:20072849 RGD:5130712, RGD:4144208, RGD:5129104, RGD:4889523 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Tnc tenascin C ISO
IMP
DNA:SNP:exon:p.L1677I (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
protein:increased expression:bronchus basement membrane
CTD
RGD
PMID:16115819 PMID:16115819 PMID:18305139 PMID:17125141 PMID:9310019 RGD:4889569, RGD:4889589, RGD:4889565, RGD:4889572 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252
JBrowse link
G Tnf tumor necrosis factor susceptibility
no_association
ISO
IMP
DNA:polymorphism:promoter: c. -308A>G (human)
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with obesity; DNA:polymorphism:promoter
DNA:polymorphisms:: rs1799964, rs1799724 (human)
DNA:polymorphisms: :
associated with nasal polys; protein:increased expression:nose
DNA:polymorphism:promoter:c.-863C > A (human)
ClinVar
OMIM
CTD
RGD
PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143443, RGD:4143238, RGD:4145508, RGD:4143240, RGD:4143254, RGD:4142802, RGD:4143369, RGD:4143372 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEP protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 severity ISO CTD Direct Evidence: marker/mechanism
ovalbumin sensitization
CTD
RGD
PMID:19458046 PMID:31969645 RGD:127285811 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086
JBrowse link
G Tslp thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850
JBrowse link
G Ucn urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chr 5:31,295,333...31,296,239
Ensembl chr 5:31,295,407...31,296,173
JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:17045018 RGD:2306832 NCBI chr 4:151,081,554...151,086,267
Ensembl chr 4:151,081,554...151,086,267
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor no_association ISO
ISS
DNA:SNP: :rs7975232 (human)
OMIM:600807
DNA:SNPs: :multiple (human)
DNA:SNP (human)
DNA:SNPs (human)
MouseDO
RGD
PMID:19622139 PMID:15282200 PMID:21103062 PMID:20124605 RGD:4889868, RGD:4889854, RGD:4889866, RGD:4889867 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11907124 PMID:15201500 PMID:19263519 PMID:19178538 RGD:6892723 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vip vasoactive intestinal polypeptide ISO
IDA
RGD PMID:21419198 PMID:16782752 RGD:5685381, RGD:5685620 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617
JBrowse link
G Wdr36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr18:32,970,241...33,000,008
Ensembl chr18:32,970,278...33,000,647
JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2-Ea histocompatibility 2, class II antigen E alpha susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,561,907...34,563,618
JBrowse link
G Tbx21 T-box 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:30643255 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Ptger2 prostaglandin E receptor 2 (subtype EP2) ISO OMIM NCBI chr14:45,225,568...45,241,277
Ensembl chr14:45,225,652...45,241,277
JBrowse link
G Tbx21 T-box 21 ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance OMIM
ClinVar
PMID:25741868 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
atopic dermatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actl9 actin-like 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr17:33,651,873...33,653,242
Ensembl chr17:33,651,870...33,653,242
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 IEA OMIM:603165 MouseDO NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
JBrowse link
G Ahr aryl-hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Apoe apolipoprotein E ISO
ISS
protein:decreased expression:plasma
OMIM:603165
MouseDO
RGD
PMID:19116453 RGD:11040546 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Artn artemin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr 4:117,783,105...117,787,993
Ensembl chr 4:117,783,359...117,786,960
JBrowse link
G Bdnf brain derived neurotrophic factor susceptibility
no_association
ISO
ISS
DNA:polymorphism::C270T(human)
OMIM:603165
protein:increased expression:serum:
DNA:polymorphism:cds:p.V66M(human)
mRNA:decreased expression:mast cell
MouseDO
RGD
PMID:19522715 PMID:17073871 PMID:19038326 PMID:17845420 RGD:8657028, RGD:8657069, RGD:8657067, RGD:8657065 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G C3 complement component 3 ISO protein:increased expression:plasma RGD PMID:3923750 RGD:7401273 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G Card11 caspase recruitment domain family, member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 PMID:28628108 NCBI chr 5:140,858,754...140,986,351
Ensembl chr 5:140,858,745...140,986,337
JBrowse link
G Casp8 caspase 8 IEA OMIM:603165 MouseDO NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Ccdc80 coiled-coil domain containing 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr16:44,913,770...44,948,287
Ensembl chr16:44,913,765...44,948,440
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
JBrowse link
G Ccl17 chemokine (C-C motif) ligand 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 severity
treatment
ISO
IEP
protein:increased expression:plasma RGD PMID:11133838 PMID:19162238 RGD:7483580, RGD:7483583 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
JBrowse link
G Ccl22 chemokine (C-C motif) ligand 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 PMID:22125604 NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327
JBrowse link
G Ccl24 chemokine (C-C motif) ligand 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
JBrowse link
G Ccl26 chemokine (C-C motif) ligand 26 ISO protein:increased expression:serum (human) RGD PMID:14616792 RGD:11087554 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423
JBrowse link
G Ccl27a chemokine (C-C motif) ligand 27A ISO RGD PMID:12642842 RGD:1626250 NCBI chr 4:41,769,467...41,774,251
Ensembl chr 4:41,769,467...41,774,247
JBrowse link
G Ccl28 chemokine (C-C motif) ligand 28 severity ISO associated with Asthma; protein: increased secretion:serum (human) RGD PMID:20161852 RGD:4892193 NCBI chr13:120,085,355...120,115,895
Ensembl chr13:120,085,355...120,115,895
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 ISO protein:increased expression:skin,monocyte: RGD PMID:15370700 RGD:8661734 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 ISO protein:increased expression:skin
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18249437 PMID:16449815 RGD:6893391 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:16449815 RGD:6893391 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cd40 CD40 antigen ISO RGD PMID:18693155 RGD:5132274 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cdsn corneodesmosin ISO protein:decreased expression:skin of body (human) RGD PMID:21211653 RGD:42721970 NCBI chr17:35,853,994...35,868,077
Ensembl chr17:35,863,025...35,868,077
JBrowse link
G Cldn1 claudin 1 ISO
ISS
mRNA,protein:decreased expression:epidermis; DNA:SNPs:intron,promoter :rs17501010,rs9290927,rs893051,rs9290929,rs16865373(human)
OMIM:603165
MouseDO
RGD
PMID:21163515 RGD:11344875 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
JBrowse link
G Cldn23 claudin 23 ISO mRNA:decreased expression:epidermis: RGD PMID:21163515 RGD:11344875 NCBI chr 8:36,291,863...36,293,713
Ensembl chr 8:36,291,866...36,293,713
JBrowse link
G Cma1 chymase 1, mast cell ISO
ISS
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
OMIM:603165
MouseDO
RGD
PMID:16134991 RGD:1625394 NCBI chr14:56,178,908...56,182,132
Ensembl chr14:56,178,908...56,182,132
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO
ISS
DNA:SNP,haplotype:exon,3'UTR:rs3087243,rs231775 (human)
OMIM:603165
mRNA:increased expression:blood:
MouseDO
RGD
PMID:16445777 PMID:22357516 RGD:7411698, RGD:7411700 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Ctse cathepsin E IEA OMIM:603165 MouseDO NCBI chr 1:131,566,052...131,603,245
Ensembl chr 1:131,566,044...131,603,243
JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 ISO protein:increased expression:serum RGD PMID:15131578 RGD:9491761 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 IMP
ISO
protein:decreased expression:blood, leukocyte RGD PMID:24821910 PMID:15131578 RGD:9491393, RGD:9491761 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 ISO ClinVar Annotator: match by term: Atopic eczema ClinVar PMID:25741868 NCBI chr17:32,671,670...32,712,294
Ensembl chr17:32,671,697...32,712,294
JBrowse link
G Dock8 dedicator of cytokinesis 8 ISO
ISS
DNA:mutations:cds:
OMIM:603165
MouseDO
RGD
PMID:22476911 RGD:40903056 NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796
JBrowse link
G Emsy EMSY, BRCA2-interacting transcriptional repressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 7:98,236,344...98,308,779
Ensembl chr 7:98,236,344...98,305,990
JBrowse link
G F2 coagulation factor II ISO protein:increased expression:plasma RGD PMID:21488867 RGD:5147756 NCBI chr 2:91,442,742...91,466,802
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III IMP RGD PMID:19414806 RGD:5508430 NCBI chr 1:170,878,738...170,893,476
Ensembl chr 1:170,878,743...170,892,504
JBrowse link
G Flg filaggrin ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Atopic eczema
CTD
ClinVar
PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17417636 More... NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993
JBrowse link
G Glb1 galactosidase, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 9:114,230,146...114,303,447
Ensembl chr 9:114,230,144...114,303,966
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 susceptibility ISO
ISS
DNA:deletion: :
OMIM:603165
MouseDO
RGD
PMID:21176116 PMID:20674822 RGD:5490539, RGD:5490981 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 susceptibility ISO
ISS
DNA:polymorphism:exon:p.I105V (rs1695) (human)
OMIM:603165
MouseDO
RGD
PMID:19842992 PMID:20674822 RGD:5490540, RGD:5490981 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 ISO
ISS
DNA:deletion, haplotype: :
OMIM:603165
MouseDO
RGD
PMID:19842992 RGD:5490540 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO
ISS
OMIM:603165 MouseDO
RGD
PMID:16159638 RGD:5128852 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Hnmt histamine N-methyltransferase ISO
ISS
OMIM:603165 MouseDO
RGD
PMID:19025430 RGD:5128889 NCBI chr 2:23,892,923...23,939,756
Ensembl chr 2:23,892,922...23,939,406
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:22101570 RGD:8157618 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifnl2 interferon lambda 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr 7:28,208,209...28,209,957
Ensembl chr 7:28,208,261...28,209,880
JBrowse link
G Il10 interleukin 10 treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:23843958 RGD:7364805 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 severity
treatment
ISO
IEA
IEP
IMP
DNA:SNPs: :rs3091307, rs20541 (human)
OMIM:603165
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:4257G>A (human)
DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
MouseDO
CTD
RGD
PMID:18249437 PMID:22355542 PMID:21913997 PMID:16672002 PMID:17313488 More... RGD:5684364, RGD:8549583, RGD:8549539, RGD:8549531, RGD:8549529, RGD:8549509 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 ISO mRNA:increased expression:skin RGD PMID:14527737 RGD:8549525 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912
JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 ISO
IMP
protein:increased expression:serum RGD PMID:21462799 PMID:20971924 RGD:8549521, RGD:8549556 NCBI chr  X:146,166,474...146,214,982
Ensembl chr  X:146,166,472...146,212,188
JBrowse link
G Il17a interleukin 17A treatment
severity
IDA
ISO
IEP
protein:increased expression:dermis, lymphocyte (human)
protein:increased expression:epidermis (mouse)
RGD PMID:24337738 PMID:18432274 PMID:22848348 RGD:8698670, RGD:9068436, RGD:9068417 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il18 interleukin 18 severity
no_association
ISO
ISS
IEA
IEP
protein:increased expression:serum
OMIM:603165
DNA:SNP:promoter:-140C>G (rs360721) (human)
DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNPs, haplotype: :rs795467, rs4937113, rs5744247 (human)
MouseDO
RGD
PMID:15317323 PMID:22840759 PMID:22840759 PMID:11490156 PMID:17517100 RGD:8655872, RGD:8655914, RGD:8655914, RGD:8655908, RGD:8655876 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 susceptibility ISO
ISS
IMP
associated with food hypersensitivity;
OMIM:603165
protein:increased expression:CD8+ T cell:
DNA:SNP:promoter:rs2069762(human)
MouseDO
RGD
PMID:7547077 PMID:1673687 PMID:16672002 PMID:16333313 PMID:21982597 RGD:8662961, RGD:8693325, RGD:8549583, RGD:8663473, RGD:8663444 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il21r interleukin 21 receptor IMP
ISO
protein:increased expression:skin RGD PMID:19075398 PMID:19075398 RGD:6892938, RGD:6892938 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742
JBrowse link
G Il25 interleukin 25 ISO protein:increased expression:arm skin RGD PMID:23657503 RGD:39128244 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294
JBrowse link
G Il31 interleukin 31 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 5:123,618,215...123,620,686
Ensembl chr 5:123,618,220...123,627,552
JBrowse link
G Il33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Il4 interleukin 4 ISO
IEA
DNA:SNP:promoter:-590C>T (human)
OMIM:603165
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
MouseDO
CTD
RGD
PMID:11886533 PMID:12230500 PMID:18249437 PMID:9643293 PMID:8363440 RGD:7829786, RGD:7829795 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il4ra interleukin 4 receptor, alpha susceptibility ISO
ISS
DNA:mutation:cds:p.Q576R(human)
OMIM:603165
MouseDO
RGD
PMID:9392697 RGD:11530001 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Il5 interleukin 5 ISO mRNA: increased expression: skin
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11886533 PMID:18249437 PMID:22299064 RGD:5687175 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 ISO ClinVar Annotator: match by term: Atopic eczema ClinVar NCBI chr 7:45,746,547...45,750,376
Ensembl chr 7:45,743,377...45,750,188
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24046278 NCBI chr14:33,099,855...33,169,215
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO
ISS
DNA:polymorphisms:promoter, exon:
OMIM:603165
MouseDO
RGD
PMID:20642202 RGD:8693720 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
JBrowse link
G Mc1r melanocortin 1 receptor IEP protein: increased expression: skin RGD PMID:19889022 RGD:5687321 NCBI chr 8:124,133,821...124,137,483
Ensembl chr 8:124,133,846...124,137,483
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP RGD PMID:27776525 RGD:13204759 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 susceptibility ISO
ISS
Atopy and bronchial hyperresponsiveness, OMIM:147050
OMIM:603165
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
MouseDO
RGD
PMID:8817330 PMID:8817330 RGD:1599903, RGD:1599903 NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083
JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) susceptibility
no_association
ISO
ISS
DNA:polymorphisms: :481C>T, 590G>A(human)
OMIM:603165
DNA:polymorphisms: :481C>T,590G>A,857G>A(human)
MouseDO
RGD
PMID:16224574 PMID:14528063 RGD:8552664, RGD:8552668 NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IEA OMIM:603165 MouseDO NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta IEA OMIM:603165 MouseDO NCBI chr16:55,631,740...55,659,004
Ensembl chr16:55,631,738...55,659,262
JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:serum: RGD PMID:17073871 RGD:8657069 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) ISO protein:increased expression:nerve fibers of the papillary dermis (human) RGD PMID:16586073 RGD:5508452 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 ISO
IMP
protein:increased expression:eosinophil RGD PMID:18647313 PMID:17223862 RGD:5144116, RGD:5684771 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
JBrowse link
G Ovol1 ovo like zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr19:5,599,165...5,610,603
Ensembl chr19:5,599,164...5,610,674
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IDA
ISO
potential therapeutic target with or without glucocorticoid therapy
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18249437 PMID:21633371 RGD:5509940 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppia peptidylprolyl isomerase A ISO mRNA:increased expression:zone of skin (human) RGD PMID:32496587 RGD:150383342 NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B IMP
IEA
OMIM:603165 MouseDO
RGD
PMID:10940923 RGD:7777149 NCBI chr 7:19,340,142...19,363,363
Ensembl chr 7:19,340,142...19,363,363
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18336422 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
JBrowse link
G Sele selectin, endothelial cell ISO CTD Direct Evidence: marker/mechanism CTD PMID:12410700 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,803...163,885,246
JBrowse link
G Selp selectin, platelet ISO
ISS
atopy and bronchial hyperresponsiveness, OMIM:147050
OMIM:603165
MouseDO
RGD
PMID:12929084 RGD:1599904 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Sharpin SHANK-associated RH domain interacting protein IEA OMIM:603165 MouseDO NCBI chr15:76,231,240...76,235,310
Ensembl chr15:76,231,240...76,235,311
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO CTD Direct Evidence: therapeutic CTD PMID:15306842 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO
ISS
OMIM:603165 MouseDO
RGD
PMID:11496247 PMID:15118671 RGD:7394812, RGD:1331525 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tlr2 toll-like receptor 2 severity ISO
ISS
DNA:polymorphism: :-16934A>T(human)
OMIM:603165
DNA:polymorphism:cds:p.R753Q(human)
MouseDO
RGD
PMID:19627277 PMID:22032785 PMID:17531301 RGD:8552997, RGD:8553048, RGD:8552999 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr4 toll-like receptor 4 ISO
ISS
DNA:polymorphism: :896G>A(human)
OMIM:603165
mRNA:increased expression:blood cell:
MouseDO
RGD
PMID:23821954 PMID:19764566 RGD:7794689, RGD:7794745 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tmem79 transmembrane protein 79 IEA OMIM:603165 MouseDO NCBI chr 3:88,235,960...88,241,740
Ensembl chr 3:88,235,962...88,243,455
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO
ISS
DNA:haplotype:promoter:−308G>A,-238G>A(human)
OMIM:603165
MouseDO
RGD
PMID:22533231 RGD:7401246 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 ISO mRNA:altered expression:fibroblast RGD PMID:16650051 RGD:7777183 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IEA OMIM:603165 MouseDO NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 IEA OMIM:603165 MouseDO NCBI chr11:73,158,315...73,191,194
Ensembl chr11:73,158,214...73,191,189
JBrowse link
G Tslp thymic stromal lymphopoietin treatment IEA
IEP
ISO
OMIM:603165
CTD Direct Evidence: marker/mechanism
MouseDO
CTD
RGD
PMID:16880407 PMID:22355542 PMID:23688403 PMID:27869817 PMID:29310423 RGD:38549374 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor severity
no_association
ISO
ISS
DNA:SNPs, haplotype: :rs731236, rs1544410, rs7975232 (human)
OMIM:603165
DNA:SNP: :rs2228570 (human)
MouseDO
RGD
PMID:23034014 PMID:23034014 RGD:8157625, RGD:8157625 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
G Vnn1 vanin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19322213 NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
JBrowse link
G Wasl WASP like actin nucleation promoting factor IEA OMIM:603165 MouseDO NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008
JBrowse link
atopic dermatitis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flg filaggrin susceptibility IEA
ISO
OMIM:605803
ClinVar Annotator: match by term: Atopic dermatitis 2 | ClinVar Annotator: match by term: Dermatitis, atopic, 2, susceptibility to
CTD Direct Evidence: marker/mechanism
MouseDO
ClinVar
CTD
OMIM
PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17291859 More... NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993
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atopic dermatitis 4 term browser