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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Immediate Hypersensitivity
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Accession:DOID:9002850 term browser browse the term
Definition:Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
Synonyms:exact_synonym: Atopic Hypersensitivities;   Atopic Hypersensitivity;   IgE Mediated Hypersensitivity;   IgE-Mediated Hypersensitivities;   Immediate Hypersensitivities;   Type I Hypersensitivities;   Type I Hypersensitivity
 primary_id: MESH:D006969
 alt_id: RDO:0001896
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
Immediate Hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 IAGP DNA:SNPs: :multiple (human) RGD PMID:16387594 RGD:5129207 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ARG2 arginase 2 IAGP DNA:SNP (human) RGD PMID:16387594 RGD:5129207 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G CCL11 C-C motif chemokine ligand 11 ISO mRNA:increased expression:nasal cavity epithelium RGD PMID:15823807 RGD:2307177 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:nasal cavity epithelium RGD PMID:15823807 RGD:2307177 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) ISO RGD PMID:9918599 RGD:2316235 NCBI chr16:72,008,744...72,027,659
Ensembl chr16:72,008,588...72,027,664
JBrowse link
G EGFR epidermal growth factor receptor IAGP DNA:snps:multiple (human) RGD PMID:20357714 RGD:5131868 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:19188657 RGD:5131872 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G FCER2 Fc epsilon receptor II EXP CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr19:7,688,776...7,702,131
Ensembl chr19:7,688,758...7,702,146
JBrowse link
G IL10 interleukin 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20485159 PMID:22967010 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL18 interleukin 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL33 interleukin 33 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983
JBrowse link
G IL4 interleukin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12755381 PMID:20485159 PMID:22967010 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility IAGP
EXP
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20485159 PMID:8817330 RGD:1599903 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467
JBrowse link
G PLA2G7 phospholipase A2 group VII EXP CTD Direct Evidence: marker/mechanism CTD PMID:10733466 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
JBrowse link
G SELP selectin P IAGP atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:point_mutation:CDS:amino acid Val640Leu RGD PMID:12929084 RGD:1599904 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193
JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 treatment IEP RGD PMID:30059697 RGD:39939057 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691
JBrowse link
G EPX eosinophil peroxidase IEP protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174
JBrowse link
G HLA-B major histocompatibility complex, class I, B susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
JBrowse link
G HLA-C major histocompatibility complex, class I, C susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130
JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP RGD PMID:22397267 RGD:13506905 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G IL25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr14:23,372,809...23,376,403
Ensembl chr14:23,372,809...23,376,403
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 PMID:21592044 RGD:126928124, RGD:126928124 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682
JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL17 C-C motif chemokine ligand 17 IEP associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:15951834 RGD:5688155 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:10946288 RGD:8661731 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CFTR CF transmembrane conductance regulator IAGP DNA:mutations: : RGD PMID:11243954 RGD:4140482 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP associated with cystic fibrosis; DNA:polymorphisms: :DQB1*06:02, DQB1*02:01(human) RGD PMID:23278646 RGD:36049760 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP associated with cystic fibrosis; DNA:polymorphisms: : RGD PMID:23278646 RGD:36049760 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:7743671 RGD:8547590 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:8699818 RGD:7794730 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
DNA:SNP:intron:1011G>A(human)
RGD PMID:11474427 PMID:16487239 RGD:4889577, RGD:8693711 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G TLR9 toll like receptor 9 susceptibility ISO
IAGP
DNA:SNP:promoter:g.-1237T>C (rs5743836) (human) RGD PMID:18936185 PMID:18275280 RGD:5130858, RGD:5130863 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:8699818 RGD:7794730 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A susceptibility IAGP DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human) RGD PMID:20646338 RGD:5131174 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
allergic conjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL11 C-C motif chemokine ligand 11 ISO mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:19553621 RGD:8548840 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCL7 C-C motif chemokine ligand 7 IEP protein:increased expression:conjunctiva RGD PMID:11090473 RGD:6483824 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:18658092 RGD:6893389 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706
JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP RGD PMID:8766745 RGD:8547686 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma ISO RGD PMID:12234900 PMID:16123425 RGD:8142386, RGD:8142391 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 treatment IEP
ISO
protein:increased expression:tear RGD PMID:22092652 PMID:16914468 PMID:15144463 PMID:19060266 RGD:7364837, RGD:11041889, RGD:7365076, RGD:7365027 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 IEP
IAGP
associated with Allergic Rhinitis;DNA:SNPs, haplotype:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human) RGD PMID:9191598 PMID:22023794 RGD:8549533, RGD:8549595 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL1B interleukin 1 beta treatment ISO RGD PMID:9326725 RGD:7401198 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment IDA human protein in a mouse model RGD PMID:10549671 RGD:8549802 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL4R interleukin 4 receptor susceptibility IAGP associated with rhinitis; DNA:SNP: : rs2107356 (human) RGD PMID:20002627 RGD:4890389 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IRF1 interferon regulatory factor 1 ISO RGD PMID:14605445 RGD:5128787 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase ISO protein:increased phosphorylation:T cell RGD PMID:14507881 RGD:1600225 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,244...32,286,165
JBrowse link
G MUC1 mucin 1, cell surface associated severity IEP RGD PMID:17177679 RGD:7349351 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming severity IEP RGD PMID:17177679 RGD:7349351 NCBI chr11:1,074,875...1,110,508
Ensembl chr11:1,074,875...1,110,511
JBrowse link
G MUC4 mucin 4, cell surface associated severity IEP
ISO
RGD PMID:17177679 PMID:11581187 RGD:7349351, RGD:7349400 NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973
JBrowse link
G PLA2G2A phospholipase A2 group IIA IEP protein:increased expression:body fluid or substance RGD PMID:21042565 RGD:6482725 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:16914468 RGD:11041889 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TLR2 toll like receptor 2 ISO associated with Staphylococcal Infections; RGD PMID:19358332 RGD:8552826 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR4 toll like receptor 4 ISO
IEP
mRNA,protein:increased expression:conjunctiva: RGD PMID:21820713 PMID:16023216 PMID:21391988 RGD:7777131, RGD:7794849, RGD:7794770 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR9 toll like receptor 9 IEP mRNA,protein:decreased expression:conjunctiva: RGD PMID:16023216 RGD:7794849 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
JBrowse link
G TNC tenascin C IAGP DNA:SNPs: :multiple (human) RGD PMID:18305139 RGD:4889589 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,257
JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 severity IAGP DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ACE angiotensin I converting enzyme no_association IAGP DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL11 C-C motif chemokine ligand 11 treatment ISO RGD PMID:23089405 RGD:7248414 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL26 C-C motif chemokine ligand 26 IEP protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896
JBrowse link
G CD40 CD40 molecule IEP protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 treatment ISO RGD PMID:10436391 RGD:11344920 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FCGR3A Fc gamma receptor IIIa susceptibility IAGP DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,366,075
JBrowse link
G HLA-G major histocompatibility complex, class I, G IEP RGD PMID:20487636 RGD:5144132 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125
JBrowse link
G HRH1 histamine receptor H1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr 3:11,137,238...11,263,557
Ensembl chr 3:11,137,093...11,263,557
JBrowse link
G IFNG interferon gamma treatment IEP
ISO
associated with Asthma RGD PMID:12787306 PMID:18510219 RGD:7829803, RGD:10755770 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 treatment IEP
ISO
RGD PMID:23883806 PMID:23253209 RGD:7364793, RGD:7364818 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 susceptibility
no_association
IAGP
EXP
DNA:SNP:promoter:-1512A>C (rs1881457) (human)
ClinVar Annotator: match by term: Allergic rhinitis
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:exon:c. 2044G>A (human)
DNA:missense mutation:cds:p.R130Q (rs20541) (human)
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)
ClinVar
CTD
OMIM
RGD
PMID:10699178 PMID:12928861 PMID:15356556 PMID:15483090 PMID:15711639 More... RGD:8549501, RGD:4152796, RGD:8549518, RGD:8549516 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 IEP protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977
JBrowse link
G IL17A interleukin 17A susceptibility IAGP
IEP
DNA:snp:promoter:c.-444A>G (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)
RGD PMID:22507625 PMID:21535180 RGD:9068429, RGD:5147409 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 severity
no_association
IAGP DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNP:promoter:-140C>G (rs360721) (human)
RGD PMID:22840759 PMID:22840759 RGD:8655914, RGD:8655914 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1B interleukin 1 beta IEP protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 ISO RGD PMID:12592663 RGD:8662963 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4 interleukin 4 treatment IEP
ISO
RGD PMID:9893928 PMID:24620662 PMID:8908280 PMID:14653048 RGD:7829796, RGD:11522769, RGD:7829827, RGD:7829802 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:23934070 PMID:24620662 RGD:11354976, RGD:11522769 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G ITGB2 integrin subunit beta 2 treatment ISO RGD PMID:12046991 RGD:9698435 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989
JBrowse link
G MUC1 mucin 1, cell surface associated severity IEP
ISO
mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 PMID:31425778 PMID:31425778 RGD:127345100, RGD:127345100, RGD:127345100 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 IEP mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077
JBrowse link
G PON1 paraoxonase 1 severity IEP protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility IAGP DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191
JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:31368266 RGD:14995445 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TLR2 toll like receptor 2 severity IAGP
IEP
ISO
DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
mRNA:decreased expression:nasal mucosa:
RGD PMID:22402138 PMID:22555057 PMID:18381801 PMID:18219831 RGD:7800732, RGD:8552993, RGD:8552972, RGD:7800742 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR4 toll like receptor 4 severity
treatment
susceptibility
no_association
IAGP
IEP
IDA
DNA:polymorphism:cds:p.D299G(human)
protein:increased expression:nasal lavage,leukocyte, bone marrow:
protein:decreased expression:nasal mucosa:
DNA:SNP: :rs1927911(human)
DNA:polymorphism: :4216G>C(human)
RGD PMID:22402138 PMID:22555057 PMID:22577387 PMID:17069098 PMID:23639307 More... RGD:7800732, RGD:8552993, RGD:7800740, RGD:7800738, RGD:7800736, RGD:4145354 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR9 toll like receptor 9 IEP protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment IAGP associated with Eosinophilic Esophagitis; DNA:polymorphisms:: RGD PMID:26416193 RGD:11352743 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G IL3 interleukin 3 susceptibility IAGP DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
JBrowse link
Anaphylaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 disease_progression ISO RGD PMID:20959119 RGD:6893644 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G AGT angiotensinogen IEP RGD PMID:1422942 RGD:8548893 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G ASPG asparaginase EXP CTD Direct Evidence: marker/mechanism CTD PMID:65671 NCBI chr14:104,085,700...104,115,582
Ensembl chr14:104,085,686...104,115,582
JBrowse link
G BTK Bruton tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796
JBrowse link
G CABS1 calcium binding protein, spermatid associated 1 treatment IDA RGD PMID:25632019 RGD:14400306 NCBI chr 4:70,334,981...70,337,116
Ensembl chr 4:70,334,981...70,337,116
JBrowse link
G CMA1 chymase 1 IEP protein:increased expression:lung, mast cell (human) RGD PMID:17081716 RGD:5128820 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265
JBrowse link
G FCGR2A Fc gamma receptor IIa susceptibility IAGP
IMP
associated with Agammaglobulinemia;DNA:mutation:splice junction: RGD PMID:23545275 PMID:26396093 RGD:11040993, RGD:11040995 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G GRAP2 GRB2 related adaptor protein 2 ameliorates ISO RGD PMID:18664516 RGD:126790488 NCBI chr22:39,893,820...39,973,721
Ensembl chr22:39,901,084...39,973,721
JBrowse link
G HDAC3 histone deacetylase 3 ISO RGD PMID:24619412 RGD:9590165 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849
JBrowse link
G HP haptoglobin IDA RGD PMID:12147031 RGD:11041789 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G IL4 interleukin 4 ISO
IEP
mRNA:increased expression:lung, intestine, spleen
associated with cystic echinococcosis; protein:increased expression:blood
RGD PMID:24468678 PMID:28095662 RGD:10402796, RGD:14696684 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G KNG1 kininogen 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:7623993 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
JBrowse link
G LTB4R leukotriene B4 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:10934231 NCBI chr14:24,311,502...24,318,036
Ensembl chr14:24,311,450...24,318,036
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19767079 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18480553 PMID:17822719 RGD:2300247, RGD:1642600 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO RGD PMID:21604443 RGD:7207802 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G WFDC6 WAP four-disulfide core domain 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20693069 NCBI chr20:45,534,196...45,539,482
Ensembl chr20:45,534,196...45,539,482
JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNG6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility IAGP DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr19:53,991,149...54,012,666
Ensembl chr19:53,991,637...54,012,666
JBrowse link
G CCR3 C-C motif chemokine receptor 3 IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20485159 PMID:20022477 RGD:4145619 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 IAGP
EXP
DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15970796 RGD:5144000 NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226
JBrowse link
G FANCC FA complementation group C IAGP DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP RGD PMID:25975240 RGD:11074090 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP RGD PMID:25975240 RGD:11074090 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP RGD PMID:25975240 RGD:11074090 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 susceptibility IAGP RGD PMID:25975240 RGD:11074090
G HLA-DRB4 major histocompatibility complex, class II, DR beta 4 susceptibility IAGP RGD PMID:25975240 RGD:11074090
G IL4 interleukin 4 susceptibility IAGP DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G LOC109286563 TBX21 promoter region IAGP ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chr17:47,731,244...47,733,243 JBrowse link
G LTC4S leukotriene C4 synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
JBrowse link
G MS4A2 membrane spanning 4-domains A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467
JBrowse link
G POSTN periostin EXP CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950
JBrowse link
G PTGER2 prostaglandin E receptor 2 IAGP
EXP
ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15496426 PMID:16502481 NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,328,598
JBrowse link
G PTGIR prostaglandin I2 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr19:46,610,687...46,625,089
Ensembl chr19:46,620,468...46,625,089
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IEP
EXP
protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:9487340 RGD:5143936 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member IAGP RGD PMID:21796142 RGD:5147839 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
JBrowse link
G TBX21 T-box transcription factor 21 IAGP
EXP
ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:15806396 PMID:16502481 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
G TBXA2R thromboxane A2 receptor susceptibility IAGP
EXP
DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16502481 PMID:20485159 PMID:15898979 RGD:11059537 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
JBrowse link
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 IEP protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 ISO RGD PMID:18931056 RGD:5128825 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association IAGP RGD PMID:19771478 PMID:16008680 RGD:5128835, RGD:5128831 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024
JBrowse link
G ACE angiotensin I converting enzyme susceptibility IAGP DNA:polymorphism (human) RGD PMID:19484664 PMID:19383228 RGD:4140913, RGD:4140919 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 IDA DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
JBrowse link
G ADA adenosine deaminase susceptibility IAGP DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252
JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 no_association
disease_progression
susceptibility
ISO
IAGP
IEA
IEP
mRNA:increased expression:lung
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :p.M764T (human)
DNA:SNPs: :multiple (human)
DNA:SNPs (human)
RGD
GAD
PMID:19635592 PMID:16893396 PMID:15118671 PMID:17339047 PMID:17961406 More... RGD:4145360, RGD:4145382, RGD:1331525, RGD:4145380, RGD:4145379, RGD:4145378, RGD:4145359 NCBI chr20:3,667,975...3,682,010
Ensembl chr20:3,667,965...3,682,246
JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 severity ISO
IEP
mRNA:increased expression:respiratory tract
mRNA:increased expression:bronchus
RGD PMID:19373511 PMID:17339047 PMID:20194813 RGD:5128878, RGD:4145380, RGD:5128872 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868
JBrowse link
G ADCY2 adenylate cyclase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081
JBrowse link
G ADCYAP1R1 ADCYAP receptor type I EXP CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr 7:31,052,308...31,111,474
Ensembl chr 7:31,052,308...31,111,479
JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO
IAGP
IEP
DNA:SNPs: :rs1154404, rs28730619 (human)
protein:increased expression:respiratory system fluid/secretion
RGD PMID:15919956 PMID:17543375 PMID:19395503 PMID:19514054 RGD:5128892, RGD:5128882, RGD:5128891, RGD:5128890 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADORA1 adenosine A1 receptor IAGP
ISO
IEP
DNA:SNPs: :1405C>T (human)
protein:increased expression:bronchus
RGD PMID:19019667 PMID:20400685 PMID:17959644 RGD:4890386, RGD:4145444, RGD:5129097 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADORA2A adenosine A2a receptor ISO
IAGP
mRNA:decreased expression:aorta
DNA:SNP (human)
RGD PMID:17293374 PMID:18310516 PMID:19019667 PMID:16339780 RGD:4890380, RGD:4890366, RGD:4890386, RGD:4890385 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility IAGP
EXP
IEA
ISO
IDA
DNA:polymorphism: :p.R16G (human)
ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to
CTD Direct Evidence: marker/mechanism
DNA:SNP: :-1023A>G (human)
DNA:SNPs: :p.R16G, p.Q27E (human)
DNA:SNPs:promoter:multiple (human)
DNA:SNP: :p.Q27E (human)
ClinVar
CTD
OMIM
RGD
PMID:8383511 PMID:15284533 PMID:16596417 PMID:19800676 PMID:19029431 More... RGD:4145061, RGD:4145092, RGD:1331525, RGD:4145081, RGD:4145094, RGD:4145107, RGD:4145108, RGD:4145105, RGD:4145096, RGD:5129113 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment
onset
IEP
EXP
ISO
CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)
CTD
RGD
PMID:23304218 PMID:33075463 PMID:21920897 PMID:23304218 RGD:7244279, RGD:6767554, RGD:7244279 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:17877756 PMID:19080339 RGD:5147452, RGD:5147457 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member IEA
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 PMID:15118671 RGD:1331525 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:19628725 PMID:18692885 RGD:5509605, RGD:5509784 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase no_association
susceptibility
treatment
severity
IAGP
EXP
IEP
ISO
IMP
DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:blood, leukocyte
protein:increased expression:lung
DNA:repeat:promoter (human)
DNA:polymorphism:cds:p.E254K (human)
CTD
OMIM
RGD
PMID:20128419 PMID:9642160 PMID:12911785 PMID:8879219 PMID:19033731 More... RGD:4890407, RGD:5147467, RGD:5147465, RGD:5147462, RGD:4890408, RGD:4890422, RGD:734557, RGD:4890413, RGD:4890415, RGD:4890410 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein no_association
susceptibility
IAGP
IEP
ISO
DNA:polymorphism:promoter (human)
mRNA:increased expression:blood, leukocyte
DNA:repeat:promoter:-169(A)21 (human)
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
protein:increased expression:lung
DNA:SNPs (human)
DNA:SNP: :rs10507391 (human)
RGD PMID:20128419 PMID:9642160 PMID:10527888 PMID:12911785 PMID:15784112 More... RGD:4890407, RGD:5147467, RGD:5147466, RGD:5147465, RGD:5147464, RGD:5147462, RGD:4890422, RGD:4890409, RGD:4890405 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor IEP protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
JBrowse link
G ANG angiogenin severity IEP protein:increased expression:sputum RGD PMID:16478840 RGD:6892719 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G AREG amphiregulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G ARG1 arginase 1 IAGP
EXP
ISO
IEP
DNA:SNP: :rs2781667 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
mRNA, protein:increased expression:lung, mononuclear cell (human)
CTD
RGD
PMID:19281908 PMID:19800904 PMID:20124949 PMID:12813022 PMID:12813022 RGD:5129205, RGD:4143187, RGD:4143187 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ARG2 arginase 2 severity
susceptibility
IAGP
EXP
ISO
DNA:SNP: :rs3742879, rs17249437 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:SNPs (human)
CTD
RGD
PMID:19281908 PMID:20124949 PMID:12813022 PMID:16387594 RGD:5129205, RGD:4143187, RGD:5129207 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G BCL2 BCL2 apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BDKRB2 bradykinin receptor B2 onset IAGP
IEP
IMP
ISO
DNA:polymorphism:exon (human)
protein:increased expression:blood, eosinophil
RGD PMID:11517947 PMID:19038786 PMID:8856156 PMID:14727005 RGD:4890456, RGD:4891028, RGD:4891042, RGD:4890454 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BDNF brain derived neurotrophic factor susceptibility
severity
IDA
IAGP
IEP
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
DNA:polymorphisms: :p.V66M (rs6265) (human)
protein:increased expression:plasma
protein:decreased expression:blood, eosinophil
RGD PMID:11737043 PMID:21723144 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891123, RGD:8655967, RGD:4891067, RGD:4891117, RGD:4891063, RGD:4891122 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B IEP protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 IEP protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G C3 complement C3 severity ISO
IEP
IAGP
protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum
Interaction with IL4RA
DNA:SNP:intron:rs11569562 (human)
DNA:SNPs: :multiple (human)
DNA:SNP: :4896C>T (human)
RGD PMID:20802484 PMID:20589464 PMID:20402389 PMID:20395963 PMID:18566738 More... RGD:5129681, RGD:5129519, RGD:5129537, RGD:5129538, RGD:5129501, RGD:5129505, RGD:5129512, RGD:5129517 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C3AR1 complement C3a receptor 1 severity ISO
IAGP
IEP
mRNA:increased expression:lung
protein:increased expression:lung, leukocyte
RGD PMID:20045013 PMID:15278436 PMID:20802484 PMID:17544263 PMID:17544263 More... RGD:5129686, RGD:5129512, RGD:5129681, RGD:5129560, RGD:5129560, RGD:5129561 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359
JBrowse link
G C5 complement C5 severity IAGP
ISO
IEP
mRNA:decreased expression:lung RGD PMID:15278436 PMID:20802484 PMID:20143644 PMID:11591795 PMID:10973279 RGD:5129512, RGD:5129681, RGD:5129706, RGD:1600651, RGD:5130158 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195
JBrowse link
G C5AR1 complement C5a receptor 1 severity ISO
IEP
protein:increased expression:respiratory tract
protein:increased expression:lung, leukocyte
RGD PMID:20802484 PMID:15940127 PMID:16511606 PMID:17544263 RGD:5129681, RGD:5129561, RGD:5130166, RGD:5129560 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066
JBrowse link
G CARD11 caspase recruitment domain family member 11 susceptibility ISO
IAGP
ClinVar Annotator: match by term: Asthma ClinVar
RGD
PMID:18323416 PMID:23129749 PMID:25741868 PMID:28492532 PMID:16751370 RGD:11100037 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228
JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr19:10,871,553...10,923,075
Ensembl chr19:10,871,553...10,923,075
JBrowse link
G CASP1 caspase 1 IEP protein:increased expression:serum RGD PMID:12396474 RGD:5130192 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CAT catalase severity IEP
EXP
IDA
IAGP
protein:increased expression:erythrocyte
CTD Direct Evidence: marker/mechanism
protein:decreased activity:respiratory system fluid/secretion
DNA:polymorphism:promoter:-262C>T (human)
DNA:polymorphism:promoter:-21A>T (human)
CTD
RGD
PMID:18048809 PMID:19475625 PMID:16622028 PMID:18048809 PMID:19373626 RGD:5130751, RGD:5130867, RGD:5130856, RGD:5130753 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL1 C-C motif chemokine ligand 1 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233
JBrowse link
G CCL11 C-C motif chemokine ligand 11 susceptibility
treatment
severity
ISO
EXP
IAGP
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
DNA:polymorphism: :p.A23T (human)
mRNA:increased expression:lung
CTD
OMIM
RGD
PMID:17060636 PMID:22932891 PMID:16304252 PMID:17074272 PMID:9034156 More... RGD:4891485, RGD:7248416, RGD:5130930, RGD:4145461, RGD:4145451, RGD:4145457, RGD:4145392, RGD:4145387 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO
IEP
mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:15993846 PMID:20074456 PMID:15947487 PMID:20237293 PMID:11160256 RGD:2306304, RGD:4145487, RGD:4145513, RGD:4145486, RGD:4145603 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063
JBrowse link
G CCL19 C-C motif chemokine ligand 19 IEP protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment
severity
IEP
EXP
ISO
IAGP
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (mouse)
DNA:haplotype::-2518A>G (human)
protein:increased expression:lung
protein:increased expression:serum
CTD
RGD
PMID:19373627 PMID:20205697 PMID:12055264 PMID:25441643 PMID:23454776 More... RGD:4145509, RGD:11528570, RGD:11528569, RGD:8551842, RGD:2307055, RGD:4891466 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL20 C-C motif chemokine ligand 20 IEP protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum
RGD PMID:18422729 PMID:22469443 RGD:7483597, RGD:7483618 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO
IEP
protein:increased expression:respiratory system fluid/secretion
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
mRNA:increased expression:lung
RGD PMID:18316417 PMID:10384142 PMID:18684970 PMID:15993846 RGD:4891474, RGD:4891475, RGD:4145489, RGD:2306304 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189
JBrowse link
G CCL24 C-C motif chemokine ligand 24 susceptibility IAGP
IEP
ISO
IMP
DNA:SNP: :1265A>G (human)
protein:increased expression:plasma
DNA:SNPs: :179T>C, 275C>T (human)
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:respiratory system fluid/secretion
RGD PMID:12761043 PMID:16304252 PMID:15207712 PMID:18712274 PMID:17060636 More... RGD:5130932, RGD:5130930, RGD:4891495, RGD:4891483, RGD:4891485, RGD:4891484, RGD:4891496 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356
JBrowse link
G CCL26 C-C motif chemokine ligand 26 treatment IAGP
ISO
IEP
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
protein:increased expression:plasma
DNA:SNPs: :77C>T, 2497T>G (human)
RGD PMID:18712274 PMID:25399816 PMID:25530546 PMID:16304252 PMID:15207712 RGD:4891483, RGD:11087575, RGD:11081163, RGD:5130930, RGD:4891495 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896
JBrowse link
G CCL27 C-C motif chemokine ligand 27 IEP RGD PMID:19541356 RGD:5130899 NCBI chr 9:34,661,890...34,662,657
Ensembl chr 9:34,661,880...34,664,048
JBrowse link
G CCL28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr 5:43,356,975...43,412,391
Ensembl chr 5:43,376,645...43,412,391
JBrowse link
G CCL4 C-C motif chemokine ligand 4 IEP RGD PMID:18774390 RGD:5130915 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO
EXP
IAGP
protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased expression:smooth muscle cell
DNA:transition:5' utr:-403G>A (human)
CTD
RGD
PMID:8534483 PMID:20092989 PMID:18208670 PMID:20430255 RGD:4891430, RGD:2307112, RGD:4891381 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO
IEP
Promoter polymorphism RGD PMID:19965981 PMID:21388664 RGD:5130979, RGD:5130983 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CCR1 C-C motif chemokine receptor 1 severity ISO mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections
RGD PMID:15654816 PMID:15593301 RGD:5688158, RGD:5688159 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
JBrowse link
G CCR2 C-C motif chemokine receptor 2 susceptibility IAGP
ISO
DNA:SNP:cds:p.V64I (human)
DNA:haplotype:cds:p.V64I(human)
protein:increased expression:lung, dendritic cell (mouse)
RGD PMID:17298432 PMID:23454776 PMID:19917684 RGD:4145110, RGD:8551842, RGD:8549811 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO
IEP
IAGP
protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)
RGD PMID:16978084 PMID:19017998 PMID:20220260 PMID:19657453 PMID:20134116 More... RGD:4145646, RGD:4145632, RGD:4145638, RGD:4145623, RGD:4145618, RGD:4145633, RGD:1601020 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706
JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,956,349
JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association IEP
IAGP
ISO
protein:decreased expression:blood, lymphocyte (human)
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
mRNA:increased expression:lung (mouse)
RGD PMID:15256090 PMID:23454776 PMID:16474097 PMID:20220260 PMID:18094012 RGD:4892108, RGD:8551842, RGD:4892093, RGD:4145638, RGD:4892088 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141
JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472
JBrowse link
G CCR8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680
JBrowse link
G CCR9 C-C motif chemokine receptor 9 IEP mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,886,509...45,903,174
JBrowse link
G CD14 CD14 molecule no_association
severity
susceptibility
IAGP
EXP
IEP
DNA:polymorphism:promoter:c. -159C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :
protein:increased expression:serum
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
DNA:polymorphism:promoter:c. -260C>T (human)
CTD
RGD
PMID:17607003 PMID:15741437 PMID:19096003 PMID:16387800 PMID:16387800 More... RGD:4144815, RGD:4144228, RGD:4144813, RGD:4144813, RGD:4144208, RGD:4144814 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CD1D CD1d molecule susceptibility ISO associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427
JBrowse link
G CD209 CD209 molecule IEP RGD PMID:21471959 RGD:5131188 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564
JBrowse link
G CD274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
JBrowse link
G CD28 CD28 molecule IEP RGD PMID:21356099 RGD:5131612 NCBI chr 2:203,706,465...203,738,912
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD40 CD40 molecule treatment IEP
ISO
IAGP
RGD PMID:19220210 PMID:20205594 PMID:20941750 PMID:19159017 RGD:5132272, RGD:8547792, RGD:4892277, RGD:4144188 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD40LG CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:21352203 PMID:21051864 PMID:21440530 RGD:5132620, RGD:5132621, RGD:5132619 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G CD86 CD86 molecule treatment ISO
IEP
IAGP
protein:increased expression:lung, alveolar macrophage (mouse)
protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)
RGD PMID:20941750 PMID:25344652 PMID:9449507 PMID:20668438 PMID:9551945 More... RGD:4892277, RGD:11354965, RGD:4892555, RGD:4892199, RGD:4892202, RGD:4892280 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDH1 cadherin 1 IAGP RGD PMID:21540309 RGD:5132878 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDHR3 cadherin related family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 7:105,963,264...106,036,432
Ensembl chr 7:105,876,796...106,036,432
JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility IAGP DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CHAT choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
JBrowse link
G CHI3L1 chitinase 3 like 1 susceptibility IMP
EXP
IAGP
IEP
human gene in mouse model
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7
DNA:snp:5' utr:g.-131C>G rs4950928 (human)
protein:increased secretion:serum (human)
CTD
OMIM
ClinVar
RGD
PMID:18403759 PMID:19414556 PMID:19568425 PMID:18003958 RGD:4892663, RGD:4892630, RGD:4892632 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G CHIA chitinase acidic no_association IAGP
ISO
IEP
DNA:snps:5' utr, cds:multiple (human)
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
mRNA:increased expression:lung (mouse)
RGD PMID:16179638 PMID:20226308 PMID:19548841 PMID:15192232 PMID:14734765 RGD:4996473, RGD:5024922, RGD:5024921, RGD:4985150, RGD:4990463 NCBI chr 1:111,290,851...111,320,563
Ensembl chr 1:111,290,851...111,320,566
JBrowse link
G CHML CHM like Rab escort protein IAGP RGD PMID:18343558 RGD:5133238 NCBI chr 1:241,628,851...241,640,369
Ensembl chr 1:241,628,851...241,640,369
JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 IAGP RGD PMID:16931638 RGD:5133416 NCBI chr11:62,908,679...62,921,878
Ensembl chr11:62,908,679...62,921,807
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 IAGP DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 severity IEP
ISO
RGD PMID:20394512 PMID:18348887 RGD:5133437, RGD:5133438 NCBI chr 1:239,386,568...239,915,450
Ensembl chr 1:239,386,565...239,915,452
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596
JBrowse link
G CLCA1 chloride channel accessory 1 susceptibility IDA
ISO
IAGP
DNA:SNPs (human) RGD PMID:17898169 PMID:11296262 PMID:15318163 RGD:4145653, RGD:4145661, RGD:4145656 NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259
JBrowse link
G CLDN18 claudin 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr 3:137,998,816...138,033,649
Ensembl chr 3:137,998,735...138,033,655
JBrowse link
G CMA1 chymase 1 severity
no_association
susceptibility
IEP
IAGP
protein:increased expression:lung epithelium, mast cell (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
RGD PMID:20813890 PMID:15248847 PMID:15924217 RGD:5128804, RGD:1625397, RGD:1625396 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 IAGP DNA:SNP: :RS242941 (human)
DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
RGD PMID:19663668 PMID:16113459 RGD:5147485, RGD:5147488 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 IAGP DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129
JBrowse link
G CRP C-reactive protein IEP protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF2 colony stimulating factor 2 severity ISO
IEP
protein:increased expression:lung
protein:increased expression:sputum
RGD PMID:20405019 PMID:9717963 PMID:19213775 RGD:5131473, RGD:10449521, RGD:5131476 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta ISO RGD PMID:17145927 RGD:1601020 NCBI chr22:36,913,628...36,940,439
Ensembl chr22:36,913,628...36,940,439
JBrowse link
G CSF3 colony stimulating factor 3 IDA
ISO
protein:increased expression:lung RGD PMID:21396376 PMID:20405019 RGD:5133731, RGD:5131473 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 severity
treatment
no_association
IEP
EXP
ISO
IDA
IAGP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3087243 (human)
DNA:polymorphism:promoter:-318C>T (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
DNA:SNPs: :multiple (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
CTD
RGD
PMID:28807506 PMID:15871446 PMID:11726402 PMID:17237396 PMID:16677453 More... RGD:4891529, RGD:11344922, RGD:4891514, RGD:4891517, RGD:4891510, RGD:4891526, RGD:4891522, RGD:4891521, RGD:4891528, RGD:4891516, RGD:4891519, RGD:4891527 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G CTNNA3 catenin alpha 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr10:65,912,523...67,763,594
Ensembl chr10:65,912,457...67,763,637
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 IEP protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 no_association ISO
IAGP
DNA:polymorphisms: :p.V249I, p.T280M (human)
DNA:SNPs: :p.V249I, rs2669849 (human)
RGD PMID:21037587 PMID:17505143 PMID:17082760 RGD:4891882, RGD:4891904, RGD:4891895 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 severity IEP RGD PMID:20371397 RGD:5134983 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 IEP
ISO
protein:decreased expression:plasma RGD PMID:17302903 PMID:16602032 PMID:11994485 RGD:5135439, RGD:5135457, RGD:5135452 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO mRNA:increased expression:lung RGD PMID:20045013 RGD:5129686 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 IEP
ISO
mRNA:increased expression:bronchus epithelium RGD PMID:17234659 PMID:9620668 RGD:5135243, RGD:5135265 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO RGD PMID:9620668 RGD:5135265 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15210824 RGD:5135447 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 susceptibility
severity
ISO
IAGP
IEP
DNA:SNP:intron:IVS1+234G>A (human)
protein:decreased expression:respiratory system fluid/secretion, T cell
RGD PMID:18094012 PMID:16043121 PMID:16548899 PMID:17641057 RGD:4892088, RGD:5143934, RGD:5143932, RGD:5135484 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511
JBrowse link
G CYBA cytochrome b-245 alpha chain susceptibility IAGP DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
DNA:polymorphism: :-930A>G (human)
RGD PMID:18716406 PMID:19459419 RGD:4772770, RGD:4311041 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 IAGP DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 IEP
EXP
ISO
mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:28807506 PMID:20514434 PMID:17081494 RGD:4892076, RGD:4892220 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 no_association
severity
IAGP
IMP
ISO
IEP
DNA:SNPs:promoter, exon:multiple (human)
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
DNA:SNP: :927T>C (human)
mRNA, protein:increased expression:respiratory system mucosa
RGD PMID:16771777 PMID:16630147 PMID:17153879 PMID:16776674 PMID:11591188 More... RGD:4889116, RGD:4784257, RGD:4781742, RGD:4782072, RGD:4848936, RGD:4888514, RGD:4843543, RGD:4781449, RGD:4847129 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 IAGP DNA:polymorphism: :601A>G (human)
DNA:polymorphism: :-1220A>C (human)
RGD PMID:15475736 PMID:15454733 RGD:5144002, RGD:5144003 NCBI chr13:48,653,929...48,711,226
Ensembl chr13:48,653,711...48,711,226
JBrowse link
G DCN decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
JBrowse link
G DEFB1 defensin beta 1 susceptibility IAGP DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
RGD PMID:15696078 PMID:16435024 RGD:4892263, RGD:4892254 NCBI chr 8:6,870,592...6,877,936
Ensembl chr 8:6,870,592...6,877,936
JBrowse link
G DNAH5 dynein axonemal heavy chain 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:13,690,328...14,011,818
Ensembl chr 5:13,690,328...14,011,818
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO
EXP
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:23423710 PMID:23196709 RGD:9588646 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DPP10 dipeptidyl peptidase like 10 IAGP
IEA
ISO
DNA:SNPs (human)
DNA:SNP: :rs10208402 (human)
protein:increased expression:bronchus
DNA:SNP:exon (human)
RGD
GAD
PMID:21103062 PMID:19672052 PMID:15118671 PMID:17967935 PMID:14566338 RGD:4889866, RGD:4892275, RGD:1331525, RGD:4892278, RGD:4892276 NCBI chr 2:114,442,641...115,845,780
Ensembl chr 2:114,442,299...115,845,780
JBrowse link
G EBI3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chr19:4,229,523...4,237,528
Ensembl chr19:4,229,523...4,237,528
JBrowse link
G EDN1 endothelin 1 IEP
EXP
IAGP
Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
CTD Direct Evidence: marker/mechanism
DNA:transition:intron:g.4124T>C (human)
CTD
RGD
PMID:16981460 PMID:20588001 PMID:11668616 RGD:4144895, RGD:4144869 NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892322, RGD:4892288 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G EDNRB endothelin receptor type B IAGP
ISO
DNA:polymorphism (human)
mRNA:increased expression:bronchus, smooth muscle cell
RGD PMID:17470272 PMID:15245576 PMID:18632188 RGD:4892321, RGD:4892324, RGD:4892288 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529
JBrowse link
G EGFR epidermal growth factor receptor severity IEP
ISO
protein:increased expression:bronchial epithelium (human)
protein:increased expression:lung epithelium (rat)
protein:increased expression:lung epithelium (mouse)
RGD PMID:12580917 PMID:21224214 PMID:19954006 PMID:21072743 RGD:5131468, RGD:5131633, RGD:5131870, RGD:5131642 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 IEP
IAGP
ISO
mRNA:increased expression:bronchoalveolar lavage cell (human)
DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
RGD PMID:18774390 PMID:18507785 PMID:11254538 RGD:5130915, RGD:5131993, RGD:5131985 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 no_association IAGP RGD PMID:12774215 PMID:11281413 RGD:5129158, RGD:5129157 NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility IAGP DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G EPX eosinophil peroxidase severity
disease_progression
IEP protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:26645423 PMID:12199967 PMID:20813885 RGD:11574908, RGD:13506892, RGD:13506891 NCBI chr17:58,192,726...58,205,174
Ensembl chr17:58,192,726...58,205,174
JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:plasma
associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus
RGD PMID:21658190 PMID:21711961 RGD:5147753, RGD:5147783 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F2RL1 F2R like trypsin receptor 1 IDA RGD PMID:19864598 RGD:4892589 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FCER1A Fc epsilon receptor Ia severity IEP Fatal asthma subjects
Asthma symptoms persistent despite steroids
RGD PMID:20937062 PMID:21388666 RGD:5128717, RGD:5128711 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224
JBrowse link
G FCGR2A Fc gamma receptor IIa IEP protein:increased expression:alveolar macrophage RGD PMID:9117017 RGD:5147982 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G FCGR2B Fc gamma receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654
JBrowse link
G FCGR3A Fc gamma receptor IIIa susceptibility IAGP DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968
JBrowse link
G FGA fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FKBP5 FKBP prolyl isomerase 5 IAGP ClinVar Annotator: match by term: Asthma ClinVar NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583
JBrowse link
G FOXP3 forkhead box P3 treatment EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27965764 PMID:29317916 PMID:28944907 PMID:27633092 RGD:38549365, RGD:38548920 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G GATA3 GATA binding protein 3 ISO
IEP
RGD PMID:18186587 PMID:9949310 RGD:5128803, RGD:5128802 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GC GC vitamin D binding protein ISO
IEP
protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 PMID:21169467 RGD:5509920, RGD:5509920 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G GSDMB gasdermin B EXP CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr17:39,904,595...39,918,635
Ensembl chr17:39,904,595...39,919,854
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 susceptibility IAGP DNA:polymorphism:promoter: -69C>T (human) RGD PMID:20374258 RGD:5490988 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860
JBrowse link
G GSTM1 glutathione S-transferase mu 1 resistance
susceptibility
IAGP
EXP
DNA:deletion: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16870661 PMID:18988661 PMID:17651144 PMID:21051083 PMID:11075422 RGD:4142509, RGD:5490962, RGD:4140921 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTM3 glutathione S-transferase mu 3 IAGP
IEP
DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135039, RGD:5135038 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
JBrowse link
G GSTO2 glutathione S-transferase omega 2 susceptibility IAGP DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr10:104,269,184...104,304,950
Ensembl chr10:104,268,873...104,304,950
JBrowse link
G GSTP1 glutathione S-transferase pi 1 no_association
susceptibility
disease_progression
severity
IAGP
EXP
ISO
DNA:SNPs: :p.I105V, p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:polymorphism:exon:p.I105V (human)
DNA:SNP: :p.A114V (human)
DNA:polymorphism:exon:p.I105V (rs1695) (human)
CTD
RGD
PMID:11994713 PMID:16870661 PMID:18988661 PMID:24117884 PMID:29411558 More... RGD:4142519, RGD:5490999, RGD:5490991, RGD:5490985, RGD:4140951, RGD:4140947, RGD:4140946, RGD:4142526 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:15300848 PMID:21051083 PMID:11075422 RGD:4142539, RGD:5490962, RGD:4140921
G HAVCR1 hepatitis A virus cellular receptor 1 IEP RGD PMID:20628202 RGD:5128851 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869
JBrowse link
G HDAC2 histone deacetylase 2 IEP mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HDC histidine decarboxylase IAGP associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HLA-B major histocompatibility complex, class I, B susceptibility IAGP DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 susceptibility IAGP DNA:polymorphism: : RGD PMID:21814517 RGD:13506911 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility IAGP
EXP
DNA:haplotype
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16792590 PMID:17956852 PMID:21217921 PMID:21814517 RGD:5143938, RGD:13506911 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP
EXP
DNA:polymorphisms (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:10792356 PMID:12890388 PMID:10051703 PMID:11802952 PMID:19052351 RGD:5147799, RGD:1331670, RGD:5147831, RGD:5147617 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 susceptibility IAGP DNA:polymorphism: :rs3916765(human) RGD PMID:20159242 RGD:13506913 NCBI chr 6:32,741,391...32,747,198
Ensembl chr 6:32,741,391...32,747,198
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility
disease_progression
no_association
IAGP
EXP
Alternaria sensitive asthma
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms (human)
CTD
RGD
PMID:10792356 PMID:20298583 PMID:20159242 PMID:20214848 PMID:23331206 More... RGD:4144113, RGD:13506913, RGD:4144181, RGD:13506906, RGD:5147831, RGD:5147799, RGD:5147617 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha susceptibility IAGP DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility
no_association
severity
IAGP
EXP
DNA:polymorphisms: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
CTD
RGD
PMID:16792590 PMID:20214848 PMID:20159242 PMID:23331206 PMID:10051703 More... RGD:4144181, RGD:13506913, RGD:13506906, RGD:1331670, RGD:5147663, RGD:5147607, RGD:4144196 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 susceptibility IAGP RGD PMID:22397267 RGD:13506905
G HLA-G major histocompatibility complex, class I, G susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD
PMID:15611928 RGD:5144118 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:20084838 RGD:5508450 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 severity IEP
EXP
ISO
mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18048809 PMID:16196283 PMID:20596599 RGD:4145408, RGD:4145403 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNMT histamine N-methyltransferase no_association
susceptibility
IAGP
EXP
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
RGD
PMID:10752634 PMID:10803682 PMID:16205835 PMID:17651147 PMID:17651147 More... RGD:5128885, RGD:5128881, RGD:5128883, RGD:5128888, RGD:5128887 NCBI chr 2:137,964,473...138,016,364
Ensembl chr 2:137,964,020...138,016,364
JBrowse link
G HP haptoglobin IEP RGD PMID:21471098 PMID:21169467 RGD:5144151, RGD:5509920 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO
EXP
IEP
mRNA:increased expression:aorta (mouse)
CTD Direct Evidence: marker/mechanism
protein:increased secretion:lung (human)
protein:increased expression:lung, serum (rat)
CTD
RGD
PMID:17014439 PMID:25003170 PMID:20400685 PMID:20205697 PMID:20953388 RGD:4145444, RGD:4145509, RGD:4145331 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma treatment
resistance
IEP
ISO
IEA
protein:increased expression:sputum RGD
GAD
PMID:20817868 PMID:12396623 PMID:15118671 PMID:20953328 PMID:19542437 RGD:4145651, RGD:10755706, RGD:1331525, RGD:4145525, RGD:5128479 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO
IAGP
DNA: SNP: Leu467Pro RGD PMID:21737883 PMID:12851715 RGD:6480255, RGD:6480431 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449
JBrowse link
G IFNL1 interferon lambda 1 exacerbates IEP associated with common cold;mRNA:decreased expression:sputum (human)
associated with common cold;protein:increased expression: nasal cavity (human)
RGD PMID:25784275 PMID:22135341 RGD:126848770, RGD:126848775 NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673
JBrowse link
G IFNL3 interferon lambda 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr19:39,243,455...39,245,250
Ensembl chr19:39,243,455...39,245,250
JBrowse link
G IKZF3 IKAROS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,718...39,864,312
JBrowse link
G IL10 interleukin 10 treatment
susceptibility
ISO
EXP
IAGP
IEP
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :-627C>A (human)
protein:decreased expression:plasma
CTD
RGD
PMID:29317916 PMID:20560982 PMID:21998459 PMID:12938145 PMID:20237464 More... RGD:5131623, RGD:11046261, RGD:4143221, RGD:4140471, RGD:4140421, RGD:4140459, RGD:4140451 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL12A interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4438438, RGD:4373570 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
JBrowse link
G IL12B interleukin 12B severity
susceptibility
IAGP DNA:polymorphisms:introns:
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:promoter
DNA:polymorphisms:promoter, 3'utr:
ClinVar
RGD
PMID:15322986 PMID:15322986 PMID:12241719 PMID:16210052 RGD:1600043, RGD:4145428, RGD:4145438 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL13 interleukin 13 susceptibility
severity
no_association
IAGP
EXP
IEP
ISO
DNA:polymorphism:promoter:c. -1055C>T (human)
ClinVar Annotator: match by term: Asthma, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Dermatitis, Atopic;DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
DNA:polymorphism: :-1512A>C, -1112C>T, 2044G>A (human)
protein:increased expression:serum
DNA:polymorphism:3'utr:c.4738G>A (human)
DNA:polymorphism: :c. 2044G>A (human)
mRNA, protein:increased expression:esophagus, Bronchoalveolar Lavage Fluid
DNA:polymorphisms:promoters,exon4: rs1881457, rs1800925, rs20541 (human)
DNA:polymorphism: :p. R110Q (human)
DNA:polymorphism: :c. 1923C>T (human)
DNA:SNP: :c. -646A>G (human)
DNA:polymorphisms: :rs20541, rs1295685(human)
DNA:polymorphism: :c.-1055C>T (human)
DNA:polymorphism:cds:p.R130Q (human)
protein:increased expression:sputum
ClinVar
OMIM
CTD
RGD
PMID:10699178 PMID:11588017 PMID:11709756 PMID:12847555 PMID:12928861 More... RGD:4220633, RGD:8549509, RGD:4892639, RGD:4763153, RGD:2301686, RGD:4765128, RGD:4145776, RGD:4145453, RGD:4145508, RGD:2307110, RGD:4145639, RGD:4145601, RGD:4145664, RGD:4321828, RGD:4145775, RGD:4146241, RGD:4145534, RGD:4145593, RGD:4763761, RGD:4145777, RGD:4206706 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 no_association ISO
IAGP
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :1398A>G (human)
DNA:polymorphism: :1050C>T (human)
RGD PMID:11714828 PMID:18480254 PMID:17392323 PMID:20383033 PMID:17006604 More... RGD:4892654, RGD:4892647, RGD:4892650, RGD:4892646, RGD:4892639, RGD:4892655 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO
IEP
mRNA:increased expression:bronchus
protein:increased expression:serum
RGD PMID:20383033 PMID:21462799 PMID:17885690 RGD:4892646, RGD:8549521, RGD:4892649 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977
JBrowse link
G IL15 interleukin 15 no_association IAGP
ISO
DNA:SNPs: :multiple (human) RGD PMID:19133918 PMID:16629787 PMID:11160248 PMID:15843549 PMID:15131572 RGD:5000760, RGD:4984421, RGD:4990462, RGD:5000757, RGD:5000758 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
JBrowse link
G IL16 interleukin 16 no_association
severity
IAGP
IEP
ISO
DNA:SNP:promoter:-295T>C (human)
associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
protein:increased expression:serum
RGD PMID:15784111 PMID:16734115 PMID:12872394 PMID:10585533 PMID:16387589 RGD:5024935, RGD:5024928, RGD:5024930, RGD:5024937, RGD:5024934 NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058
JBrowse link
G IL17A interleukin 17A susceptibility IEP
ISO
IAGP
protein:increased expression:sputum
DNA:SNP:promoter:rs2275913 (human)
protein:increased expression:alveolar macrophage
mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
RGD PMID:15730730 PMID:20351038 PMID:20437253 PMID:18941201 PMID:18060619 RGD:4889114, RGD:4888527, RGD:4889139, RGD:4889152, RGD:4839043 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL17RB interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr 3:53,846,568...53,865,794
Ensembl chr 3:53,846,568...53,865,794
JBrowse link
G IL18 interleukin 18 severity
susceptibility
disease_progression
IAGP
ISO
IMP
IEP
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
DNA:polymorphism: :c. -105A>C (human)
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
protein:increased expression:serum
RGD PMID:17767553 PMID:18826499 PMID:20497957 PMID:20497957 PMID:16433859 More... RGD:4889585, RGD:4889908, RGD:4889898, RGD:4889898, RGD:4889923, RGD:4889910, RGD:4889900, RGD:4889863 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL18R1 interleukin 18 receptor 1 IAGP
ISO
DNA:SNPs: :multiple (human)
DNA:SNP: :rs3771166 (human)
RGD PMID:18774397 PMID:19910030 PMID:20860503 PMID:11972614 PMID:18382474 RGD:5024946, RGD:5024945, RGD:5024942, RGD:5024948, RGD:5024947 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777
JBrowse link
G IL19 interleukin 19 IEP protein:increased expression:serum RGD PMID:15557163 RGD:5037236 NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981
JBrowse link
G IL1A interleukin 1 alpha IAGP DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta susceptibility IAGP
EXP
ISO
IEP
DNA:polymorphism: :-511C>T (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil
CTD
RGD
PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142864, RGD:4142836, RGD:4142830 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 susceptibility
severity
ISO
EXP
IAGP
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1420101 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNP: :rs1041973 (human)
CTD
RGD
PMID:19198610 PMID:21150878 PMID:21804549 PMID:24241537 PMID:27472835 More... RGD:5144235, RGD:5144245, RGD:5144244, RGD:5144243, RGD:5144242, RGD:5144240, RGD:5144239, RGD:5144237 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
JBrowse link
G IL1RN interleukin 1 receptor antagonist severity
susceptibility
IEP
EXP
IAGP
IMP
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:intron (human)
DNA:SNP: :rs2234678 (human)
DNA:SNPs: :rs447713, rs3087271 (human)
DNA:SNPs: :multiple (human)
DNA, protein:repeat, decreased expression (human)
CTD
RGD
PMID:9176529 PMID:10843772 PMID:18926055 PMID:17107994 PMID:16409203 More... RGD:4143225, RGD:4142864, RGD:4143208, RGD:4143163, RGD:4143209, RGD:4143216, RGD:4142802, RGD:4143224 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL2 interleukin 2 susceptibility IEP
IAGP
DNA:SNP:promoter:rs2069762(human) RGD PMID:20926789 PMID:16333313 RGD:4889118, RGD:8663473 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL21 interleukin 21 IAGP DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066
JBrowse link
G IL22 interleukin 22 treatment
severity
ISO
IEP
mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum
RGD PMID:21789181 PMID:21998459 PMID:21535180 PMID:21297073 RGD:5147401, RGD:11046261, RGD:5147409, RGD:5147403 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604
JBrowse link
G IL23R interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979
JBrowse link
G IL25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr14:23,372,809...23,376,403
Ensembl chr14:23,372,809...23,376,403
JBrowse link
G IL27 interleukin 27 susceptibility
treatment
IAGP
ISO
IEP
DNA:SNP: :g.-964A>G (human)
protein:increased expression:sputum
RGD PMID:17318299 PMID:26595888 PMID:17878337 PMID:20817868 PMID:19542437 RGD:5128485, RGD:11076728, RGD:5128491, RGD:4145651, RGD:5128479 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051
JBrowse link
G IL27RA interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chr19:14,031,762...14,053,218
Ensembl chr19:14,031,762...14,053,218
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:21377197 PMID:20525707 RGD:5147437, RGD:5147445 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
JBrowse link
G IL2RB interleukin 2 receptor subunit beta IAGP
ISO
DNA:SNP: :rs2284033 (human) RGD PMID:20860503 PMID:18641329 RGD:5024942, RGD:5147447 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118
JBrowse link
G IL3 interleukin 3 susceptibility IAGP DNA:SNP: :rs40401(human)
DNA:polymorphism:cds:+79T>C(S27P)(human)
RGD PMID:24684517 PMID:15372320 RGD:13506914, RGD:13506916 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
JBrowse link
G IL32 interleukin 32 IEP protein:increased expression:blood serum (human) RGD PMID:22336080 RGD:150340749 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192
JBrowse link
G IL33 interleukin 33 treatment
severity
EXP
ISO
IEP
CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease
CTD
RGD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:27472835 PMID:29067999 More... RGD:39939002, RGD:39938968 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983
JBrowse link
G IL4 interleukin 4 treatment
no_association
IAGP
EXP
ISO
IEP
DNA:polymorphism (human)
CTD Direct Evidence: marker/mechanism
mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:lung
DNA:SNP: :589C>T (human)
mRNA:increased expression:lung, spleen
protein:increased expression:respiratory system fluid/secretion
CTD
RGD
PMID:18357729 PMID:21103062 PMID:24946644 PMID:24450480 PMID:18211752 More... RGD:4889866, RGD:10402799, RGD:10402791, RGD:2317290, RGD:5128560, RGD:5128500, RGD:5128502, RGD:5128557 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor susceptibility
severity
disease_progression
ISO
ISS
IAGP
IDA
IEP
DNA:mutation:cds:p.Q576R (mouse)
OMIM:600807
DNA:polymorphism:promoter:c.-3223C>T (human)
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:polymorphism:cds:p.I50V (human)
DNA:polymorphism:cds:p.Q551R (human)
DNA:polymorphism::-1902G/A (human)
DNA:SNPs: :multiple
protein:increased secretion:plasma
DNA:polymorphism:cds:p.Q576R (human)
DNA:polymorphism:cds:p. S478P (human)
DNA:SNPs:cds:p.E375A, Q551R (human)
MouseDO
RGD
PMID:19770271 PMID:15479272 PMID:12133990 PMID:18425216 PMID:17586032 More... RGD:4890003, RGD:4890351, RGD:4890404, RGD:4890346, RGD:4890348, RGD:4890406, RGD:4890387, RGD:4890347, RGD:4890351, RGD:4890402, RGD:5128514, RGD:4890024, RGD:5128553, RGD:4890352, RGD:4890349 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL5 interleukin 5 treatment
disease_progression
ISO
EXP
IEP
IAGP
IDA
CTD Direct Evidence: marker/mechanism
protein:increased expression:lungs, respiratory system fluid/secretion
protein: increased levels: sputum
protein:increased expression:respiratory system fluid/secretion
DNA:polymorphism:promoter:-703C>T (human)
CTD
RGD
PMID:7540862 PMID:23266719 PMID:19947994 PMID:25008888 PMID:11159041 More... RGD:4890938, RGD:11354973, RGD:5687189, RGD:5687144, RGD:5687140, RGD:4890962, RGD:4890947, RGD:4890963, RGD:4145461, RGD:4890940, RGD:4890948 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL5RA interleukin 5 receptor subunit alpha IAGP
ISO
IEP
IMP
DNA:SNPs (human)
DNA:SNP: :c.25091G>A (human)
RGD PMID:16217591 PMID:17276963 PMID:20592918 PMID:10224351 PMID:20513521 More... RGD:5128626, RGD:5128617, RGD:5128614, RGD:5128623, RGD:5128625, RGD:5128627 NCBI chr 3:3,066,324...3,110,374
Ensembl chr 3:3,066,324...3,126,613
JBrowse link
G IL6 interleukin 6 IEP
EXP
ISO
associated with Hypersensitivity;protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD
RGD
PMID:29902480 PMID:20816188 PMID:20840469 PMID:20658762 PMID:21115736 RGD:4143266, RGD:4143265, RGD:4143271, RGD:5128630 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6R interleukin 6 receptor ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29902480 PMID:17496315 PMID:21115736 RGD:5128662, RGD:5128630 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G IL9 interleukin 9 ISO
IMP
IEP
protein:increased expression:respiratory system fluid/secretion
protein:increased expression:sputum, macrophage, cytoplasm
RGD PMID:12153980 PMID:21356110 PMID:15531759 PMID:17446528 PMID:15303135 RGD:5128700, RGD:5128707, RGD:5128690, RGD:5128686, RGD:5128691 NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841
JBrowse link
G IL9R interleukin 9 receptor IEP RGD PMID:10629460 RGD:5128704 NCBI chr  X:155,997,696...156,013,020
NCBI chr  Y:57,184,072...57,197,869
Ensembl chr  X:155,997,696...156,010,817
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 susceptibility IAGP
EXP
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:17503328 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622
JBrowse link
G IRF1 interferon regulatory factor 1 no_association
susceptibility
IAGP
IEP
DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
protein:increased expression:respiratory tract epithelium
DNA:repeat:intron (human)
RGD PMID:11069564 PMID:10225979 PMID:16961714 RGD:5128726, RGD:5128723, RGD:5128724 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G IRF3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G ITGB3 integrin subunit beta 3 IAGP DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G ITGB6 integrin subunit beta 6 ISS OMIM:600807 MouseDO NCBI chr 2:160,099,671...160,200,272
Ensembl chr 2:160,099,667...160,200,313
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
JBrowse link
G KDR kinase insert domain receptor ISO
IEP
associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:20921519 PMID:17651148 RGD:5684385, RGD:8551771 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KIF3A kinesin family member 3A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:132,688,812...132,737,546
Ensembl chr 5:132,692,628...132,737,638
JBrowse link
G KRT19 keratin 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308
JBrowse link
G LEP leptin IEP protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LGALS3 galectin 3 treatment IMP RGD PMID:16424226 RGD:9685213 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
JBrowse link
G LTA lymphotoxin alpha susceptibility
no_association
IAGP DNA:polymorphisms:promoter
DNA:polymorphism:intron
RGD PMID:15969671 PMID:18947013 PMID:12530118 PMID:17536219 RGD:4143373, RGD:4143370, RGD:4143254, RGD:4143371 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G LTA4H leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP associated with Bronchiolitis;DNA:polymorphism:exon:
DNA:SNP:cds:p.G54D(human)
RGD PMID:22512728 PMID:22674410 RGD:8693709, RGD:12910828 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility IAGP DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633
JBrowse link
G MIF macrophage migration inhibitory factor severity IAGP
ISO
IEP
DNA:SNP:promoter:rs755622(human)
protein:increased expression:bronchoalveolar lavage fluid
DNA:repeats:promoter
RGD PMID:19317738 PMID:17373669 PMID:9637721 PMID:16455830 PMID:16186482 RGD:4891059, RGD:4891035, RGD:4891043, RGD:1641985, RGD:4891052 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MMP1 matrix metallopeptidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP10 matrix metallopeptidase 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628
JBrowse link
G MMP9 matrix metallopeptidase 9 IEP
EXP
IMP
IAGP
ISO
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP: : rs2664538(human)
mRNA, protein:increased expression:lung
CTD
RGD
PMID:11742282 PMID:15131573 PMID:21439806 PMID:19940022 PMID:20181264 More... RGD:5129204, RGD:5129522, RGD:5130859, RGD:2325953, RGD:5129687 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase susceptibility IEP
IAGP
protein:increased expression:serum
DNA:polymorphism: :−463G > A (human)
RGD PMID:10731862 PMID:19544176 RGD:5130994, RGD:5130989 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility IAGP DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNP: : -109C>T (human)
RGD PMID:19218813 PMID:21320344 PMID:8817330 PMID:19862939 RGD:5131151, RGD:5131149, RGD:1599903, RGD:5131092 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467
JBrowse link
G MTHFR methylenetetrahydrofolate reductase IAGP DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MUC1 mucin 1, cell surface associated IEP protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming IAGP
ISO
associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178, RGD:7349354 NCBI chr11:1,074,875...1,110,508
Ensembl chr11:1,074,875...1,110,511
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming treatment IEP
ISO
protein:increased expression:lung
mRNA, protein:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:17698377 PMID:21549818 PMID:21780541 PMID:14594655 PMID:17590487 RGD:5131204, RGD:7364729, RGD:7349407, RGD:7349354, RGD:2324962 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming IEP
ISO
protein:altered expression:sputum RGD PMID:11802783 PMID:11587997 RGD:5131252, RGD:7364763 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172
JBrowse link
G MUC7 mucin 7, secreted susceptibility IAGP
EXP
ClinVar Annotator: match by term: Asthma, protection against
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:11378823 PMID:16759176 NCBI chr 4:70,430,492...70,482,997
Ensembl chr 4:70,430,492...70,482,997
JBrowse link
G MYB MYB proto-oncogene, transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,478...38,143,024
JBrowse link
G MYLK myosin light chain kinase IAGP RGD PMID:17472811 RGD:4891492 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP Asthma, Aspirin-Induced; DNA:polymorphism: :
DNA:polymorphisms: :
RGD PMID:20602614 PMID:16924569 RGD:5131600, RGD:5131606 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 severity IEP mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NGF nerve growth factor severity IDA
IEP
ISO
protein:increased expression:lung, serum
protein:increased expression:blood, eosinophil
RGD PMID:11737043 PMID:17164945 PMID:17497413 PMID:12752594 RGD:4891123, RGD:4891108, RGD:4891068, RGD:4891122 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:16603479 PMID:12540484 RGD:5144070, RGD:5144072 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility IAGP DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:
RGD PMID:16918516 PMID:15718249 RGD:5131519, RGD:5131518 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility IAGP
ISO
DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477, RGD:5508757 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077
JBrowse link
G NOS1 nitric oxide synthase 1 susceptibility IAGP DNA:repeats: :
DNA:repeats:intron
DNA:repeats:exon
RGD PMID:10673365 PMID:20609134 PMID:14767694 PMID:10833424 RGD:5132869, RGD:5132863, RGD:5132615, RGD:5132860 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 disease_progression
no_association
severity
ISO
EXP
IEP
IAGP
protein:increased expression:lung, bronchoalveolar lavage fluid
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:lung (rat)
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:repeat:promoter
DNA:repeats:promoter
mRNA:increased expression:monocyte
DNA:repeats:promoter, introns (human)
DNA:SNP:exon:p.S608L (human)
CTD
RGD
PMID:19800904 PMID:17161822 PMID:21847581 PMID:18254476 PMID:16703578 More... RGD:4891927, RGD:5509073, RGD:4891910, RGD:4891953, RGD:4891508, RGD:4891419, RGD:4891957, RGD:4891924, RGD:4891925, RGD:4891480 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility IAGP DNA:repeats:intron
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892062, RGD:4892058, RGD:4892053 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NPSR1 neuropeptide S receptor 1 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2
CTD
OMIM
ClinVar
RGD
PMID:15073379 PMID:15710598 PMID:15764725 PMID:16926187 PMID:17702965 More... RGD:4891923, RGD:4891921, RGD:4891922 NCBI chr 7:34,658,218...34,878,332
Ensembl chr 7:34,658,218...34,878,332
JBrowse link
G NPSR1-AS1 NPSR1 antisense RNA 1 IAGP ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2 ClinVar PMID:15073379 NCBI chr 7:34,346,512...34,834,331
Ensembl chr 7:34,346,512...34,871,582
JBrowse link
G NPY neuropeptide Y EXP CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 susceptibility IDA
EXP
IAGP
DNA:SNP:exon:c. 609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c.609C>T (human)
CTD
RGD
PMID:20049212 PMID:19027876 PMID:19591959 RGD:5135006, RGD:5135005 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment
severity
susceptibility
IEP
ISO
IDA
IAGP
protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron
RGD PMID:18396779 PMID:20727335 PMID:18799869 PMID:15295049 PMID:21113676 RGD:4892328, RGD:7174728, RGD:4892594, RGD:4892609, RGD:4892568 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G NTF3 neurotrophin 3 IDA
ISO
protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891123, RGD:4891068 NCBI chr12:5,430,332...5,495,299
Ensembl chr12:5,432,108...5,521,536
JBrowse link
G NTF4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr19:49,058,284...49,065,035
Ensembl chr19:49,061,066...49,065,076
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:lung: RGD PMID:20934630 PMID:16708804 RGD:5684766, RGD:5684772 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,640...156,881,850
JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr17:39,921,041...39,927,601
Ensembl chr17:39,921,041...39,927,601
JBrowse link
G P2RY12 purinergic receptor P2Y12 IAGP
ISO
RGD PMID:22010907 PMID:19822647 RGD:6480532, RGD:6480533 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 treatment ISO
EXP
IDA
CTD Direct Evidence: marker/mechanism
protein:increased activation:lung, blood, mononuclear cell
CTD
RGD
PMID:18261157 PMID:12594058 PMID:26205779 PMID:26205779 RGD:5683910, RGD:11073727, RGD:11073727 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PDCD1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894
JBrowse link
G PDE4B phosphodiesterase 4B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579
JBrowse link
G PDE4D phosphodiesterase 4D EXP CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 PMID:21216974 RGD:6483071, RGD:6483071 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PGF placental growth factor IDA RGD PMID:22268141 RGD:6483605 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,689
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
JBrowse link
G PLA2G7 phospholipase A2 group VII susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma and atopy, susceptibility to
OMIM
CTD
ClinVar
RGD
PMID:10733466 PMID:15115767 PMID:10733466 RGD:1581025 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
JBrowse link
G PLAU plasminogen activator, urokinase IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21912604 PMID:18519237 RGD:4892037 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073
JBrowse link
G PRF1 perforin 1 ISO RGD PMID:22250087 PMID:21426642 RGD:6482815, RGD:6482818 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759
JBrowse link
G PRG2 proteoglycan 2, pro eosinophil major basic protein severity
disease_progression
no_association
IEP
ISO
mRNA:increased expression:eosinophil:
associated with cough;protein:increased expression:sputum:
associated with viral infection;mRNA:increased expression:sputum:
RGD PMID:16982448 PMID:22022864 PMID:24450586 PMID:11067904 RGD:13506941, RGD:13506944, RGD:13506943, RGD:13506942 NCBI chr11:57,386,780...57,390,650
Ensembl chr11:57,386,780...57,390,650
JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029
JBrowse link
G PRMT2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr21:46,635,674...46,665,124
Ensembl chr21:46,635,595...46,665,124
JBrowse link
G PRMT3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr11:20,387,716...20,509,338
Ensembl chr11:20,387,558...20,509,338
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr14:22,920,529...22,929,376
Ensembl chr14:22,920,525...22,929,408
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment IDA RGD PMID:26381519 RGD:11099992 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242
JBrowse link
G PTEN phosphatase and tensin homolog EXP CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGDR prostaglandin D2 receptor susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr14:52,267,698...52,280,914
Ensembl chr14:52,267,698...52,276,724
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 IAGP
EXP
ISO
CTD Direct Evidence: therapeutic
Aspirin exacerbated asthma
CTD
RGD
PMID:27103662 PMID:19392992 PMID:19796209 PMID:18757520 RGD:5135019, RGD:5135020, RGD:5135018 NCBI chr11:60,850,933...60,855,950
Ensembl chr11:60,850,933...60,855,950
JBrowse link
G PTGER3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,816
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO
IAGP
IMP
mRNA:increased expression:lung
DNA:SNP: :8473T>C (human)
mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)
RGD PMID:19878559 PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 More... RGD:5135514, RGD:5143931, RGD:5143923, RGD:5135534, RGD:5135526, RGD:5135522, RGD:5135515 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr 1:158,931,552...158,990,870
Ensembl chr 1:158,930,796...158,977,059
JBrowse link
G RAD50 RAD50 double strand break repair protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G RNASE3 ribonuclease A family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8874658 PMID:12153692 PMID:12587966 NCBI chr14:20,891,385...20,892,348
Ensembl chr14:20,891,385...20,892,348
JBrowse link
G RUNX1 RUNX family transcription factor 1 IAGP DNA:SNPs: :multiple RGD PMID:21803869 RGD:6482835 NCBI chr21:35,372,507...35,580,764
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX3 RUNX family transcription factor 3 ISS OMIM:600807 MouseDO NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 susceptibility ISO
IAGP
IEP
mRNA,protein:decreased expression:bronchial alveolar lavage fluid, lung:
ClinVar Annotator: match by term: Asthma, susceptibility to
associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
protein:decreased expression:serum
ClinVar
RGD
PMID:9550363 PMID:12921604 PMID:21255142 PMID:15467329 RGD:5144052, RGD:5144226, RGD:5144148 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility
severity
no_association
IAGP
EXP
ISO
IEP
DNA:SNP:promoter:-112G>A (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Asthma, susceptibility to
mRNA,protein:decreased expression:;lung
protein:increased expression:sputum
CTD
OMIM
ClinVar
RGD
PMID:11813133 PMID:11813133 PMID:15531759 PMID:16456148 PMID:17218572 More... RGD:5144229, RGD:5128690, RGD:5144233, RGD:5144232, RGD:5144231, RGD:5144230 NCBI chr 5:147,878,711...147,882,191
Ensembl chr 5:147,870,682...147,882,191
JBrowse link
G SELL selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685, RGD:5685696 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702
JBrowse link
G SERPINA1 serpin family A member 1 ISO Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693
JBrowse link
G SERPINE1 serpin family E member 1 severity
no_association
susceptibility
IEP
ISO
IAGP
protein:increased expression:plasma
protein:increased activity, increased expression:plasma, lung
DNA:polymorphism:promoter:rs1799768 (human)
RGD PMID:19703828 PMID:18594148 PMID:19604112 PMID:19063817 RGD:4144831, RGD:4144836, RGD:4144833, RGD:4144832 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SFTPA1 surfactant protein A1 ISO
IEP
protein:decreased expression:lung, Clara cell, pneumocyte
mRNA, protein:increased expression:lung
RGD PMID:15816355 PMID:16629790 PMID:18926058 PMID:18802356 RGD:4143398, RGD:4143462, RGD:4143289, RGD:4143516 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455
JBrowse link
G SFTPB surfactant protein B IEP
ISO
protein:increased expression:lung
mRNA, protein:decreased expression:lung
protein:decreased expression:lung, Clara cell
RGD PMID:16629790 PMID:11472974 PMID:15816355 PMID:18926058 RGD:4143462, RGD:4143465, RGD:4143398, RGD:4143289 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741
JBrowse link
G SFTPC surfactant protein C susceptibility IAGP
IEP
ISO
DNA:polymorphism: :p.A53T (human)
protein:increased expression:lung
mRNA, protein:decreased expression:lung
RGD PMID:19910179 PMID:16629790 PMID:11472974 RGD:4144063, RGD:4143462, RGD:4143465 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479
JBrowse link
G SFTPD surfactant protein D IEP
ISO
IDA
associated with Bronchitis;protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:18266831 PMID:11472974 PMID:16839409 PMID:16629790 PMID:18802356 RGD:4143517, RGD:4143465, RGD:4143508, RGD:4143462, RGD:4143516 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720
JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:17328924 RGD:5686690 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718
JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr 2:107,986,524...108,013,994
Ensembl chr 2:107,986,523...108,013,994
JBrowse link
G SLC6A4 solute carrier family 6 member 4 susceptibility IAGP DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
JBrowse link
G SOD1 superoxide dismutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 IDA RGD PMID:15743779 RGD:1581231 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPRR2B small proline rich protein 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 1:153,070,226...153,087,799
Ensembl chr 1:153,070,226...153,071,611
JBrowse link
G STAT4 signal transducer and activator of transcription 4 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28807506 PMID:18211752 RGD:2317290 NCBI chr 2:191,029,576...191,246,175
Ensembl chr 2:191,029,576...191,151,596
JBrowse link
G STAT6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:19087723 PMID:16083555 RGD:7244151, RGD:7244153 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
JBrowse link
G TAC1 tachykinin precursor 1 IEP protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TACR1 tachykinin receptor 1 ISO
IEP
protein:increased expression:lung
mRNA:increased expression:lung
mRNA,protein:increased expression:lung
RGD PMID:17392578 PMID:8240667 PMID:16409782 RGD:2304339, RGD:5147645, RGD:5147475 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
JBrowse link
G TACR2 tachykinin receptor 2 IAGP
IMP
DNA:SNP:cds:p.G231E (human) RGD PMID:20175803 PMID:19880429 RGD:5147640, RGD:5147641 NCBI chr10:69,403,903...69,416,918
Ensembl chr10:69,403,903...69,416,918
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility IAGP DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
JBrowse link
G TBX21 T-box transcription factor 21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15806396 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
G TBXA2R thromboxane A2 receptor susceptibility
severity
IEA
IAGP
DNA:polymorphism:cds:924T>C(human) GAD
RGD
PMID:15118671 PMID:12000493 PMID:15805995 RGD:1331525, RGD:11059535, RGD:11059534 NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
JBrowse link
G TGFB1 transforming growth factor beta 1 onset
no_association
IAGP
EXP
ISO
IEP
DNA:SNP: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:915G>C (human)
protein:increased expression:serum
mRNA:increased expression:lung
DNA:SNPs:promoter, exon:multiple (human)
DNA:polymorphism: :-509C>T (human)
DNA:polymorphisms: :multiple (human)
CTD
RGD
PMID:16365456 PMID:19138248 PMID:17673695 PMID:18366906 PMID:19620629 More... RGD:4145295, RGD:4145280, RGD:4145132, RGD:4145142, RGD:4145139, RGD:4145113, RGD:4145143, RGD:4143443, RGD:4145144, RGD:4145299, RGD:4145297 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G THBD thrombomodulin IDA RGD PMID:20709825 RGD:5684984 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041
JBrowse link
G TLR1 toll like receptor 1 susceptibility IAGP DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817
JBrowse link
G TLR10 toll like receptor 10 susceptibility IAGP DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 4:38,772,238...38,782,990
Ensembl chr 4:38,772,238...38,782,990
JBrowse link
G TLR2 toll like receptor 2 severity
susceptibility
IAGP
ISO
DNA:SNP: :rs3804100 (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :rs4696480 (human)
DNA:SNP: :rs7656411 (human)
DNA:SNP: :596T>C (human)
RGD PMID:19148143 PMID:22402138 PMID:18202345 PMID:20685742 PMID:20815312 More... RGD:2312679, RGD:7800732, RGD:4145343, RGD:4144171, RGD:4145352, RGD:4145334, RGD:4144228 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR3 toll like receptor 3 no_association IEP
IAGP
ISO
Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
DNA:snp:cds:p.L412F (human)
RGD PMID:21129050 PMID:14987294 PMID:17610940 PMID:21364926 PMID:17434873 RGD:5129226, RGD:5129493, RGD:5129475, RGD:5128500, RGD:5129478 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073
JBrowse link
G TLR4 toll like receptor 4 susceptibility
no_association
severity
IAGP
ISO
IEP
DNA:Polymorphism:cds:p.D299G (human)
protein:decreased expression:leukocytes, mononuclear
DNA:SNPs: :rs10983755, rs1927914 (human)
DNA:SNPs::
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
RGD PMID:15356557 PMID:20628601 PMID:19067129 PMID:19330007 PMID:19159017 More... RGD:4144817, RGD:4144176, RGD:4144190, RGD:4144141, RGD:4144188, RGD:4144171, RGD:4144198 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR6 toll like receptor 6 susceptibility IAGP DNA:SNP: :p.S249P (human)
DNA:SNP (human)
RGD PMID:15266299 PMID:18547625 RGD:4889538, RGD:4889528 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817
JBrowse link
G TLR9 toll like receptor 9 susceptibility
severity
no_association
IAGP
ISO
IEP
DNA:SNP:promoter:g.-1237T>C (rs5743836) (human)
protein:increased expression:peripheral blood mononuclear cell (human)
DNA:SNP:promoter:g.-1237T>C rs5743836 (human)
RGD PMID:18312481 PMID:20016192 PMID:20072849 PMID:21324137 RGD:4144208, RGD:5129104, RGD:4889523, RGD:5130712 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
JBrowse link
G TNC tenascin C ISO
EXP
IAGP
IEP
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple (human)
DNA:SNP:exon:p.L1677I (human)
protein:increased expression:bronchus basement membrane
CTD
RGD
PMID:16115819 PMID:17125141 PMID:18305139 PMID:16115819 PMID:9310019 RGD:4889565, RGD:4889589, RGD:4889569, RGD:4889572 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,257
JBrowse link
G TNF tumor necrosis factor susceptibility
no_association
IAGP
EXP
ISO
IEP
associated with obesity; DNA:polymorphism:promoter
ClinVar Annotator: match by term: ASTHMA, BRONCHIAL
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter: c. -308A>G (human)
DNA:polymorphisms:: rs1799964, rs1799724 (human)
DNA:polymorphisms: :
associated with nasal polys; protein:increased expression:nose
DNA:polymorphism:promoter:c.-863C > A (human)
ClinVar
OMIM
CTD
RGD
PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143238, RGD:4143443, RGD:4143254, RGD:4143240, RGD:4145508, RGD:4142802, RGD:4143369, RGD:4143372 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 severity EXP
ISO
CTD Direct Evidence: marker/mechanism
ovalbumin sensitization
CTD
RGD
PMID:19458046 PMID:31969645 RGD:127285811 NCBI chr 8:72,021,250...72,090,010
Ensembl chr 8:72,019,917...72,075,584
JBrowse link
G TSLP thymic stromal lymphopoietin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026
JBrowse link
G UCN urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445
JBrowse link
G UTS2 urotensin 2 IEP RGD PMID:17045018 RGD:2306832 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512
JBrowse link
G VDR vitamin D receptor no_association IAGP DNA:SNPs (human)
DNA:SNP (human)
DNA:SNPs: :multiple (human)
DNA:SNP: :rs7975232 (human)
RGD PMID:20124605 PMID:21103062 PMID:15282200 PMID:19622139 RGD:4889867, RGD:4889866, RGD:4889854, RGD:4889868 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
JBrowse link
G VEGFA vascular endothelial growth factor A IEP
EXP
protein:increased expression:sputum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11907124 PMID:15201500 PMID:19263519 PMID:19178538 RGD:6892723 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:21419198 PMID:16782752 RGD:5685381, RGD:5685620 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765
JBrowse link
G WDR36 WD repeat domain 36 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 5:111,092,348...111,130,502
Ensembl chr 5:111,092,321...111,130,502
JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DRA major histocompatibility complex, class II, DR alpha susceptibility IAGP DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
JBrowse link
G LOC109286563 TBX21 promoter region IAGP ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr17:47,731,244...47,733,243 JBrowse link
G TBX21 T-box transcription factor 21 IAGP ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase IAGP ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:30643255 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G PTGER2 prostaglandin E receptor 2 IAGP OMIM NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,328,598
JBrowse link
G TBX21 T-box transcription factor 21 IAGP ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance OMIM
ClinVar
PMID:25741868 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
atopic dermatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTL9 actin like 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr19:8,697,400...8,698,795
Ensembl chr19:8,697,400...8,698,795
JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 ISS OMIM:603165 MouseDO NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
JBrowse link
G AHR aryl hydrocarbon receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G APOE apolipoprotein E IDA protein:decreased expression:plasma RGD PMID:19116453 RGD:11040546 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ARTN artemin EXP CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr 1:43,933,801...43,937,240
Ensembl chr 1:43,933,320...43,937,240
JBrowse link
G BDNF brain derived neurotrophic factor susceptibility
no_association
IAGP
IEP
DNA:polymorphism::C270T(human)
protein:increased expression:serum:
DNA:polymorphism:cds:p.V66M(human)
mRNA:decreased expression:mast cell
RGD PMID:19522715 PMID:17073871 PMID:19038326 PMID:17845420 RGD:8657028, RGD:8657069, RGD:8657067, RGD:8657065 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G C3 complement C3 IEP protein:increased expression:plasma RGD PMID:3923750 RGD:7401273 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CARD11 caspase recruitment domain family member 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042114 PMID:28628108 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228
JBrowse link
G CASP8 caspase 8 ISS OMIM:603165 MouseDO NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CCDC80 coiled-coil domain containing 80 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 3:112,596,797...112,641,143
Ensembl chr 3:112,596,797...112,649,530
JBrowse link
G CCL11 C-C motif chemokine ligand 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL17 C-C motif chemokine ligand 17 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063
JBrowse link
G CCL20 C-C motif chemokine ligand 20 severity
treatment
IEP
ISO
protein:increased expression:plasma RGD PMID:11133838 PMID:19162238 RGD:7483580, RGD:7483583 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCL22 C-C motif chemokine ligand 22 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 PMID:22125604 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189
JBrowse link
G CCL24 C-C motif chemokine ligand 24 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356
JBrowse link
G CCL26 C-C motif chemokine ligand 26 IEP protein:increased expression:serum (human) RGD PMID:14616792 RGD:11087554 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896
JBrowse link
G CCL27 C-C motif chemokine ligand 27 IEP RGD PMID:12642842 RGD:1626250 NCBI chr 9:34,661,890...34,662,657
Ensembl chr 9:34,661,880...34,664,048
JBrowse link
G CCL28 C-C motif chemokine ligand 28 severity IEP associated with Asthma; protein: increased secretion:serum (human) RGD PMID:20161852 RGD:4892193 NCBI chr 5:43,356,975...43,412,391
Ensembl chr 5:43,376,645...43,412,391
JBrowse link
G CCL5 C-C motif chemokine ligand 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCR2 C-C motif chemokine receptor 2 IEP protein:increased expression:skin,monocyte: RGD PMID:15370700 RGD:8661734 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CCR3 C-C motif chemokine receptor 3 IEP
EXP
protein:increased expression:skin
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18249437 PMID:16449815 RGD:6893391 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706
JBrowse link
G CCR5 C-C motif chemokine receptor 5 IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:16449815 RGD:6893391 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
JBrowse link
G CD40 CD40 molecule IEP RGD PMID:18693155 RGD:5132274 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CDSN corneodesmosin IEP protein:decreased expression:skin of body (human) RGD PMID:21211653 RGD:42721970 NCBI chr 6:31,115,087...31,120,446
Ensembl chr 6:31,115,087...31,120,446
JBrowse link
G CLDN1 claudin 1 IEP
IAGP
mRNA,protein:decreased expression:epidermis:
DNA:SNPs:intron,promoter :rs17501010,rs9290927,rs893051,rs9290929,rs16865373(human)
RGD PMID:21163515 PMID:21163515 RGD:11344875, RGD:11344875 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
JBrowse link
G CLDN23 claudin 23 IEP mRNA:decreased expression:epidermis: RGD PMID:21163515 RGD:11344875 NCBI chr 8:8,701,937...8,704,096
Ensembl chr 8:8,701,937...8,704,096
JBrowse link
G CMA1 chymase 1 IAGP DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human) RGD PMID:16134991 RGD:1625394 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility IAGP
IEP
DNA:SNP,haplotype:exon,3'UTR:rs3087243,rs231775 (human)
mRNA:increased expression:blood:
RGD PMID:16445777 PMID:22357516 RGD:7411698, RGD:7411700 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G CTSE cathepsin E ISS OMIM:603165 MouseDO NCBI chr 1:206,009,264...206,023,895
Ensembl chr 1:206,008,535...206,023,909
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 IEP protein:increased expression:serum RGD PMID:15131578 RGD:9491761 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO
IEP
protein:decreased expression:blood, leukocyte RGD PMID:24821910 PMID:15131578 RGD:9491393, RGD:9491761 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 IAGP ClinVar Annotator: match by term: Dermatitis, atopic ClinVar PMID:25741868 NCBI chr19:15,508,525...15,552,317
Ensembl chr19:15,508,525...15,552,317
JBrowse link
G DOCK8 dedicator of cytokinesis 8 IAGP DNA:mutations:cds: RGD PMID:22476911 RGD:40903056 NCBI chr 9:211,257...465,255
Ensembl chr 9:214,854...465,259
JBrowse link
G EMSY EMSY transcriptional repressor, BRCA2 interacting EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr11:76,445,018...76,553,031
Ensembl chr11:76,444,923...76,553,031
JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:plasma RGD PMID:21488867 RGD:5147756 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FCGR2A Fc gamma receptor IIa severity IEP
ISO
protein:increased expression:eosinophil RGD PMID:7564170 PMID:19414806 RGD:5147985, RGD:5508430 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G FLG filaggrin EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Dermatitis, atopic
CTD
ClinVar
PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17417636 More... NCBI chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239
JBrowse link
G GLB1 galactosidase beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr 3:32,961,108...33,097,146
Ensembl chr 3:32,996,609...33,097,202
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion: : RGD PMID:21176116 PMID:20674822 RGD:5490539, RGD:5490981 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:19842992 PMID:20674822 RGD:5490540, RGD:5490981 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP DNA:deletion, haplotype: : RGD PMID:19842992 RGD:5490540
G HAVCR1 hepatitis A virus cellular receptor 1 IAGP RGD PMID:16159638 RGD:5128852 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
JBrowse link
G HNMT histamine N-methyltransferase IAGP RGD PMID:19025430 RGD:5128889 NCBI chr 2:137,964,473...138,016,364
Ensembl chr 2:137,964,020...138,016,364
JBrowse link
G IFNG interferon gamma IEP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:22101570 RGD:8157618 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFNL3 interferon lambda 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22295096 NCBI chr19:39,243,455...39,245,250
Ensembl chr19:39,243,455...39,245,250
JBrowse link
G IL10 interleukin 10 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:23843958 RGD:7364805 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 severity
treatment
IAGP
EXP
IEP
ISO
DNA:SNPs: :rs3091307, rs20541 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:4257G>A (human)
DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
CTD
RGD
PMID:18249437 PMID:22355542 PMID:21913997 PMID:16672002 PMID:17313488 More... RGD:5684364, RGD:8549583, RGD:8549539, RGD:8549531, RGD:8549529, RGD:8549509 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 IEP mRNA:increased expression:skin RGD PMID:14527737 RGD:8549525 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 IEP
ISO
protein:increased expression:serum RGD PMID:21462799 PMID:20971924 RGD:8549521, RGD:8549556 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977
JBrowse link
G IL17A interleukin 17A treatment
severity
ISO
IEP
protein:increased expression:dermis, lymphocyte (human)
protein:increased expression:epidermis (mouse)
RGD PMID:24337738 PMID:18432274 PMID:22848348 RGD:8698670, RGD:9068436, RGD:9068417 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 severity
no_association
IEP
ISS
IAGP
ISO
protein:increased expression:serum
OMIM:603165
DNA:SNP:promoter:-140C>G (rs360721) (human)
DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNPs, haplotype: :rs795467, rs4937113, rs5744247 (human)
MouseDO
RGD
PMID:15317323 PMID:22840759 PMID:22840759 PMID:11490156 PMID:17517100 RGD:8655872, RGD:8655914, RGD:8655914, RGD:8655908, RGD:8655876 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 susceptibility IDA
IEP
IAGP
ISO
associated with food hypersensitivity;
protein:increased expression:CD8+ T cell:
DNA:SNP:promoter:rs2069762(human)
RGD PMID:7547077 PMID:1673687 PMID:16672002 PMID:16333313 PMID:21982597 RGD:8662961, RGD:8693325, RGD:8549583, RGD:8663473, RGD:8663444 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL21R interleukin 21 receptor ISO
IEP
protein:increased expression:skin RGD PMID:19075398 PMID:19075398 RGD:6892938, RGD:6892938 NCBI chr16:27,402,174...27,452,042
Ensembl chr16:27,402,174...27,452,042
JBrowse link
G IL25 interleukin 25 IEP protein:increased expression:arm skin RGD PMID:23657503 RGD:39128244 NCBI chr14:23,372,809...23,376,403
Ensembl chr14:23,372,809...23,376,403
JBrowse link
G IL31 interleukin 31 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr12:122,172,029...122,174,221
Ensembl chr12:122,172,029...122,174,221
JBrowse link
G IL32 interleukin 32 IEP mRNA:splice variant:zone of skin (human) RGD PMID:28301691 RGD:150340720 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192
JBrowse link
G IL33 interleukin 33 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983
JBrowse link
G IL4 interleukin 4 IAGP
EXP
IEP
DNA:SNP:promoter:-590C>T (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD
RGD
PMID:11886533 PMID:12230500 PMID:18249437 PMID:9643293 PMID:8363440 RGD:7829786, RGD:7829795 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor susceptibility IAGP DNA:mutation:cds:p.Q576R(human) RGD PMID:9392697 RGD:11530001 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL5 interleukin 5 IEP
EXP
mRNA: increased expression: skin
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11886533 PMID:18249437 PMID:22299064 RGD:5687175 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 IAGP ClinVar Annotator: match by term: Dermatitis, atopic ClinVar NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24046278 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:polymorphisms:promoter, exon: RGD PMID:20642202 RGD:8693720 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MC1R melanocortin 1 receptor ISO protein: increased expression: skin RGD PMID:19889022 RGD:5687321 NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO RGD PMID:27776525 RGD:13204759 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility IAGP Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G RGD PMID:8817330 RGD:1599903 NCBI chr11:60,088,259...60,098,467
Ensembl chr11:60,088,261...60,098,467
JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility
no_association
IAGP DNA:polymorphisms: :481C>T, 590G>A(human)
DNA:polymorphisms: :481C>T,590G>A,857G>A(human)
RGD PMID:16224574 PMID:14528063 RGD:8552664, RGD:8552668 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G NFKBIA NFKB inhibitor alpha ISS OMIM:603165 MouseDO NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NFKBIZ NFKB inhibitor zeta ISS OMIM:603165 MouseDO NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022
JBrowse link
G NGF nerve growth factor IEP protein:increased expression:serum: RGD PMID:17073871 RGD:8657069 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NGFR nerve growth factor receptor IEP protein:increased expression:nerve fibers of the papillary dermis RGD PMID:16586073 RGD:5508452 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IEP
ISO
protein:increased expression:eosinophil RGD PMID:18647313 PMID:17223862 RGD:5144116, RGD:5684771 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,640...156,881,850
JBrowse link
G OVOL1 ovo like transcriptional repressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr11:65,787,063...65,797,214
Ensembl chr11:65,787,063...65,797,214
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO
EXP
potential therapeutic target with or without glucocorticoid therapy (mouse)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18249437 PMID:21633371 RGD:5509940 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPIA peptidylprolyl isomerase A HEP mRNA:increased expression:zone of skin (human) RGD PMID:32496587 RGD:150383342 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit ISO
ISS
OMIM:603165 MouseDO
RGD
PMID:10940923 RGD:7777149 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192
JBrowse link
G S100A8 S100 calcium binding protein A8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18336422 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
JBrowse link
G SELE selectin E EXP CTD Direct Evidence: marker/mechanism CTD PMID:12410700 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
JBrowse link
G SELP selectin P IAGP atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:point_mutation:CDS:amino acid Val640Leu RGD PMID:12929084 RGD:1599904 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193
JBrowse link
G SHARPIN SHANK associated RH domain interactor ISS OMIM:603165 MouseDO NCBI chr 8:144,098,637...144,103,773
Ensembl chr 8:144,098,633...144,108,124
JBrowse link
G SLC11A1 solute carrier family 11 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894
JBrowse link
G STAT6 signal transducer and activator of transcription 6 EXP CTD Direct Evidence: therapeutic CTD PMID:15306842 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
JBrowse link
G TGFB1 transforming growth factor beta 1 IEA
IAGP
GAD
RGD
PMID:15118671 PMID:11496247 RGD:1331525, RGD:7394812 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TLR2 toll like receptor 2 severity IAGP
IDA
DNA:polymorphism: :-16934A>T(human)
DNA:polymorphism:cds:p.R753Q(human)
RGD PMID:19627277 PMID:22032785 PMID:17531301 RGD:8552997, RGD:8553048, RGD:8552999 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR4 toll like receptor 4 IAGP
IEP
DNA:polymorphism: :896G>A(human)
mRNA:increased expression:blood cell:
RGD PMID:23821954 PMID:19764566 RGD:7794689, RGD:7794745 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TMEM79 transmembrane protein 79 ISS OMIM:603165 MouseDO NCBI chr 1:156,282,932...156,292,443
Ensembl chr 1:156,282,935...156,293,185
JBrowse link
G TNF tumor necrosis factor susceptibility IAGP DNA:haplotype:promoter:−308G>A,-238G>A(human) RGD PMID:22533231 RGD:7401246 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 IEP mRNA:altered expression:fibroblast RGD PMID:16650051 RGD:7777183 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 ISS OMIM:603165 MouseDO NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906
JBrowse link
G TRPV3 transient receptor potential cation channel subfamily V member 3 ISS OMIM:603165 MouseDO NCBI chr17:3,510,502...3,557,812
Ensembl chr17:3,510,502...3,557,812
JBrowse link
G TSLP thymic stromal lymphopoietin treatment EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16880407 PMID:22355542 PMID:23688403 PMID:27869817 PMID:29310423 RGD:38549374 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026
JBrowse link
G VDR vitamin D receptor severity
no_association
IAGP DNA:SNPs, haplotype: :rs731236, rs1544410, rs7975232 (human)
DNA:SNP: :rs2228570 (human)
RGD PMID:23034014 PMID:23034014 RGD:8157625, RGD:8157625 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
JBrowse link
G VNN1 vanin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19322213 NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055
JBrowse link
G VNN2 vanin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19322213 NCBI chr 6:132,743,870...132,763,455
Ensembl chr 6:132,743,870...132,763,459
JBrowse link
G WASL WASP like actin nucleation promoting factor ISS OMIM:603165 MouseDO NCBI chr 7:123,681,943...123,749,003
Ensembl chr 7:123,681,943...123,749,003
JBrowse link
G ZNF365 zinc finger protein 365 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr10:62,374,369...62,480,285
Ensembl chr10:62,374,192...62,480,288
JBrowse link
atopic dermatitis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLG filaggrin susceptibility IAGP
EXP
ClinVar Annotator: match by term: Dermatitis, atopic, 2
ClinVar Annotator: match by term: Dermatitis, atopic, 2, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17291859