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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Immediate Hypersensitivity
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Accession:DOID:9002850 term browser browse the term
Definition:Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
Synonyms:exact_synonym: Atopic Hypersensitivities;   Atopic Hypersensitivity;   IgE Mediated Hypersensitivity;   IgE-Mediated Hypersensitivities;   Immediate Hypersensitivities;   Type I Hypersensitivities;   Type I Hypersensitivity
 primary_id: MESH:D006969
 alt_id: RDO:0001896
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
Immediate Hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 ISO DNA:SNPs: :multiple (human) RGD PMID:16387594 RGD:5129207 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305
JBrowse link
G ARG2 arginase 2 ISO DNA:SNP (human) RGD PMID:16387594 RGD:5129207 NCBI chr 8:41,588,051...41,619,406
Ensembl chr 8:41,588,150...41,619,402
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:nasal cavity epithelium RGD PMID:15823807 RGD:2307177 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) ISO RGD PMID:9918599 RGD:2316235 NCBI chr 5:77,756,411...77,766,207
Ensembl chr 5:77,756,407...77,774,090
JBrowse link
G EGFR epidermal growth factor receptor ISO DNA:snps:multiple (human) RGD PMID:20357714 RGD:5131868 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:19188657 RGD:5131872 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575
JBrowse link
G FCER2 Fc epsilon receptor II ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr20:52,451,637...52,460,045
Ensembl chr20:52,449,922...52,457,805
JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL13 interleukin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 PMID:22967010 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22967010 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721
JBrowse link
G IL4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12755381 PMID:20485159 PMID:22967010 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL4R interleukin 4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility ISO Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8817330 PMID:20485159 RGD:1599903 NCBI chr21:50,439,133...50,456,785
Ensembl chr21:50,450,024...50,456,785
JBrowse link
G PLA2G7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism CTD PMID:10733466 NCBI chr12:14,866,229...14,908,230
Ensembl chr12:14,866,229...14,908,114
JBrowse link
G SELP selectin P ISO atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:point_mutation:CDS:amino acid Val640Leu RGD PMID:12929084 RGD:1599904 NCBI chr 7:28,956,428...28,997,266
Ensembl chr 7:28,958,486...28,996,313
JBrowse link
acute asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:30059697 RGD:39939057 NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354
JBrowse link
allergic asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 treatment ISO RGD PMID:25530546 RGD:11081163 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 treatment ISO RGD PMID:23933317 RGD:40903070 NCBI chr  X:60,462,290...60,513,155
Ensembl chr  X:60,463,526...60,464,548
JBrowse link
G DLA88 MHC class I DLA-88 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr12:892,442...895,691
Ensembl chr12:892,388...1,021,690
JBrowse link
G EPX eosinophil peroxidase ISO protein:increased expression:urine: RGD PMID:11846868 RGD:13506893 NCBI chr 9:32,855,568...32,865,445
Ensembl chr 9:32,855,507...32,865,022
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain susceptibility ISO RGD PMID:22397267 RGD:13506905 NCBI chr12:2,151,409...2,164,564 JBrowse link
G IL25 interleukin 25 treatment ISO RGD PMID:17889290 RGD:40902975 NCBI chr 8:3,621,268...3,624,689
Ensembl chr 8:3,618,161...3,624,043
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates ISO RGD PMID:21592044 RGD:126928124 NCBI chr12:9,990,678...10,000,195
Ensembl chr12:9,990,679...10,000,236
JBrowse link
allergic bronchopulmonary aspergillosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL17 C-C motif chemokine ligand 17 ISO associated with Cystic Fibrosis RGD PMID:17898016 RGD:4145612 NCBI chr 2:59,001,463...59,014,347
Ensembl chr 2:59,001,464...59,005,230
JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 ISO RGD PMID:15951834 RGD:5688155 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:10946288 RGD:8661731 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
G CFTR CF transmembrane conductance regulator ISO DNA:mutations: : RGD PMID:11243954 RGD:4140482 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain susceptibility ISO associated with cystic fibrosis; DNA:polymorphisms: : RGD PMID:23278646 RGD:36049760 NCBI chr12:2,151,409...2,164,564 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:7743671 RGD:8547590 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:8699818 RGD:7794730 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G MBL1 mannose binding lectin 1 susceptibility ISO Chronic Necrotizing Pulmonary Aspergillosis; DNA:missense mutation:exon:p.R52C (human)
DNA:SNP:intron:1011G>A(human)
RGD PMID:11474427 PMID:16487239 RGD:4889577 RGD:8693711 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G TLR9 toll like receptor 9 susceptibility ISO DNA:SNP:promoter:g.-1237T>C (rs5743836) (human) RGD PMID:18275280 PMID:18936185 RGD:5130858 RGD:5130863 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:8699818 RGD:7794730 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A susceptibility ISO DNA:snps:5' utr, exon:g.-609G>T rs4149570, g.36A>G rs767455 (human) RGD PMID:20646338 RGD:5131174 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282
JBrowse link
allergic conjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 treatment ISO RGD PMID:16914468 RGD:11041889 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:19553621 RGD:8548840 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:conjunctiva RGD PMID:12682842 RGD:2307196 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO protein:increased expression:conjunctiva RGD PMID:11090473 RGD:6483824 NCBI chr 9:38,994,638...38,996,103
Ensembl chr 9:38,993,911...39,010,483
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:18658092 RGD:6893389 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:8766745 RGD:8547686 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G IFNG interferon gamma ISO RGD PMID:12234900 PMID:16123425 RGD:8142386 RGD:8142391 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL10 interleukin 10 treatment ISO protein:increased expression:tear RGD PMID:15144463 PMID:16914468 PMID:19060266 PMID:22092652 RGD:11041889 RGD:7364837 RGD:7365027 RGD:7365076 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL13 interleukin 13 ISO associated with Allergic Rhinitis;DNA:SNPs, haplotype:promoter, exon:-1112C>T (rs1800925), p.R130Q (rs20541) (human) RGD PMID:9191598 PMID:22023794 RGD:8549533 RGD:8549595 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL1B interleukin 1 beta treatment ISO RGD PMID:9326725 RGD:7401198 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO human protein in a mouse model RGD PMID:10549671 RGD:8549802 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329
JBrowse link
G IL4R interleukin 4 receptor susceptibility ISO associated with rhinitis; DNA:SNP: : rs2107356 (human) RGD PMID:20002627 RGD:4890389 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G IRF1 interferon regulatory factor 1 ISO RGD PMID:14605445 RGD:5128787 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase ISO protein:increased phosphorylation:T cell RGD PMID:14507881 RGD:1600225 NCBI chr 2:68,940,816...68,964,585
Ensembl chr 2:68,941,249...68,964,567
JBrowse link
G MUC1 mucin 1, cell surface associated severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming severity ISO RGD PMID:17177679 RGD:7349351 NCBI chr18:45,416,347...45,438,226 JBrowse link
G MUC4 mucin 4, cell surface associated severity ISO RGD PMID:11581187 PMID:17177679 RGD:7349351 RGD:7349400 NCBI chr33:29,061,372...29,084,938
Ensembl chr33:29,063,096...29,111,802
JBrowse link
G TLR2 toll like receptor 2 ISO associated with Staphylococcal Infections; RGD PMID:19358332 RGD:8552826 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR4 toll like receptor 4 ISO mRNA,protein:increased expression:conjunctiva: RGD PMID:16023216 PMID:21391988 PMID:21820713 RGD:7777131 RGD:7794770 RGD:7794849 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TLR9 toll like receptor 9 ISO mRNA,protein:decreased expression:conjunctiva: RGD PMID:16023216 RGD:7794849 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114
JBrowse link
G TNC tenascin C ISO DNA:SNPs: :multiple (human) RGD PMID:18305139 RGD:4889589 NCBI chr11:69,077,532...69,169,673
Ensembl chr11:69,077,535...69,170,281
JBrowse link
allergic rhinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 severity ISO DNA:snp:exon:c.1236C>T (human) RGD PMID:24040855 RGD:8657076 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ACE angiotensin I converting enzyme no_association ISO DNA:deletion:intron:IVS16+1464-1751del (human) RGD PMID:15112973 RGD:8142345 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G B9D2 B9 domain containing 2 treatment ISO RGD PMID:31368266 RGD:14995445 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA, protein:increased expression:nasal mucosa (rat) RGD PMID:15362690 RGD:11522724 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29028686 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
JBrowse link
G CCL26 C-C motif chemokine ligand 26 ISO protein:increased expression:oronasal secretion (human) RGD PMID:23883806 RGD:7364793 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726
JBrowse link
G CD40 CD40 molecule ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CD40LG CD40 ligand ISO protein:increased expression:lymphocyte RGD PMID:19086656 RGD:8547782 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 treatment ISO RGD PMID:10436391 RGD:11344920 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G F2 coagulation factor II, thrombin ISO protein:increased expression:nasal mucus RGD PMID:21711961 RGD:5147783 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr 4:55,801,269...56,103,383
Ensembl chr 4:55,803,296...56,103,669
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34624383 NCBI chr15:54,634,332...54,710,711
Ensembl chr15:54,634,335...54,708,184
JBrowse link
G HRH1 histamine receptor H1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23333628 NCBI chr20:7,160,903...7,236,147
Ensembl chr20:7,162,393...7,235,869
JBrowse link
G IFNG interferon gamma treatment ISO associated with Asthma RGD PMID:12787306 PMID:18510219 RGD:10755770 RGD:7829803 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:23253209 PMID:23883806 RGD:7364793 RGD:7364818 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL13 interleukin 13 susceptibility
no_association
ISO ClinVar Annotator: match by term: Allergic rhinitis
DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (rs1800925, rs20541) (human)
OMIM
ClinVar
RGD
PMID:10699178 PMID:12928861 PMID:15356556 PMID:15483090 PMID:15711639 RGD:8549516 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum RGD PMID:21462799 RGD:8549521 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798
JBrowse link
G IL17A interleukin 17A susceptibility ISO DNA:snp:promoter:c.-444A>G (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)
RGD PMID:21535180 PMID:22507625 RGD:5147409 RGD:9068429 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL18 interleukin 18 no_association
severity
ISO DNA:SNP:promoter:-140C>G (rs360721) (human)
DNA:SNP:promoter:-137G>C (rs187238) (human)
RGD PMID:22840759 RGD:8655914 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7750009 RGD:7401199 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL2 interleukin 2 ISO RGD PMID:12592663 RGD:8662963 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G IL4 interleukin 4 treatment ISO RGD PMID:8908280 PMID:9893928 PMID:14653048 PMID:24620662 RGD:11522769 RGD:7829796 RGD:7829802 RGD:7829827 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:23934070 PMID:24620662 RGD:11354976 RGD:11522769 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G ITGB2 integrin subunit beta 2 treatment ISO RGD PMID:12046991 RGD:9698435 NCBI chr31:38,520,733...38,547,003
Ensembl chr31:38,521,103...38,547,018
JBrowse link
G LOC478984 low affinity immunoglobulin gamma Fc region receptor III susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr38:21,054,870...21,060,948 JBrowse link
G MUC1 mucin 1, cell surface associated severity ISO mRNA,protein:decreased expression:nasal mucosa RGD PMID:31425778 RGD:127345100 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO mRNA, protein:increased expression:nasal cavity epithelium RGD PMID:22972875 RGD:7364746 NCBI chr18:45,471,232...45,498,961 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO mRNA:increased expression:nasal mucosa (human) RGD PMID:23858718 RGD:8547523 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232
JBrowse link
G PON1 paraoxonase 1 severity ISO protein:decreased activity:plasma (human) RGD PMID:23406590 RGD:8547583 NCBI chr14:20,565,620...20,600,774
Ensembl chr14:20,565,641...20,642,985
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO protein:increased expression:nasal cavity epithelium RGD PMID:24012634 RGD:7775060 NCBI chr26:35,732,974...36,932,744
Ensembl chr26:35,737,242...36,932,729
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16979129 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO mRNA:decreased expression:nasal mucosa, lung RGD PMID:17882576 RGD:5144135 NCBI chr18:54,187,487...54,191,493
Ensembl chr18:54,187,487...54,191,482
JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility ISO DNA:SNP: :rs7726552 (human) RGD PMID:21410962 RGD:5144225 NCBI chr 2:42,147,596...42,151,224
Ensembl chr 2:42,147,596...42,151,191
JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA:increased expression:nasal mucosa (mouse) RGD PMID:21339035 RGD:8547809 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:nasal mucosa RGD PMID:12768696 RGD:5147835 NCBI chr17:48,038,010...48,178,971
Ensembl chr17:48,038,010...48,178,971
JBrowse link
G TLR2 toll like receptor 2 severity ISO mRNA:decreased expression:nasal mucosa:
DNA:polymorphism:cds:p.R753Q(human)
protein:increased expression:neutrophil:
RGD PMID:18219831 PMID:18381801 PMID:22402138 PMID:22555057 RGD:7800732 RGD:7800742 RGD:8552972 RGD:8552993 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR4 toll like receptor 4 treatment
severity
no_association
susceptibility
ISO protein:decreased expression:nasal mucosa:
DNA:polymorphism:cds:p.D299G(human)
DNA:polymorphism: :4216G>C(human)
protein:increased expression:nasal lavage,leukocyte, bone marrow:
DNA:SNP: :rs1927911(human)
RGD PMID:17069098 PMID:19763595 PMID:22402138 PMID:22555057 PMID:22577387 More... RGD:4145354 RGD:7800732 RGD:7800736 RGD:7800738 RGD:7800740 RGD:8552993 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TLR9 toll like receptor 9 ISO protein:decreased expression:nasal mucosa: RGD PMID:22577387 RGD:7800740 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114
JBrowse link
Allergic Rhinoconjunctivitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL3 interleukin 3 susceptibility ISO DNA:SNP: :rs40401(human) RGD PMID:23953855 RGD:13506915 NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668
JBrowse link
Anaphylaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 disease_progression ISO RGD PMID:20959119 RGD:6893644 NCBI chr28:24,908,224...24,909,684
Ensembl chr28:24,908,224...24,909,684
JBrowse link
G AGT angiotensinogen ISO RGD PMID:1422942 RGD:8548893 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G ASPG asparaginase ISO CTD Direct Evidence: marker/mechanism CTD PMID:65671 NCBI chr 8:71,747,319...71,764,570
Ensembl chr 8:71,753,164...71,765,349
JBrowse link
G BTK Bruton tyrosine kinase treatment ISO RGD PMID:22228807 RGD:11040701 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G CABS1 calcium binding protein, spermatid associated 1 treatment ISO RGD PMID:25632019 RGD:14400306 NCBI chr13:59,691,575...59,712,204 JBrowse link
G CMA1 chymase 1 ISO protein:increased expression:lung, mast cell (human) RGD PMID:17081716 RGD:5128820 NCBI chr 8:4,438,244...4,441,189
Ensembl chr 8:4,438,244...4,441,189
JBrowse link
G GRAP2 GRB2 related adaptor protein 2 ameliorates ISO RGD PMID:18664516 RGD:126790488 NCBI chr10:25,156,233...25,220,106
Ensembl chr10:25,157,841...25,220,222
JBrowse link
G HDAC3 histone deacetylase 3 ISO RGD PMID:24619412 RGD:9590165 NCBI chr 2:36,583,283...36,598,121
Ensembl chr 2:36,583,283...36,597,682
JBrowse link
G IL4 interleukin 4 ISO mRNA:increased expression:lung, intestine, spleen
associated with cystic echinococcosis; protein:increased expression:blood
RGD PMID:24468678 PMID:28095662 RGD:10402796 RGD:14696684 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G KNG1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7623993 NCBI chr34:19,288,629...19,318,096
Ensembl chr34:19,287,109...19,318,081
JBrowse link
G LTB4R leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10934231 NCBI chr 8:4,282,924...4,286,869
Ensembl chr 8:4,285,323...4,286,534
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19767079 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:18480553 RGD:2300247 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:17822719 PMID:18480553 RGD:1642600 RGD:2300247 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO RGD PMID:21604443 RGD:7207802 NCBI chr 6:49,341,669...49,359,841
Ensembl chr 6:49,342,151...49,359,933
JBrowse link
aspirin-induced respiratory disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNG6 calcium voltage-gated channel auxiliary subunit gamma 6 susceptibility ISO DNA:SNP,haplotype:rs192808(human) RGD PMID:20860846 RGD:13524562 NCBI chr 1:103,227,936...103,244,263
Ensembl chr 1:103,226,597...103,244,441
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:20022477 PMID:20485159 RGD:4145619 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 PMID:17641958 PMID:20485159 NCBI chr  X:60,462,290...60,513,155
Ensembl chr  X:60,463,526...60,464,548
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO DNA:SNPs: :-819T>G, 2078C>T, 2534A>G (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15970796 PMID:16502481 PMID:20485159 RGD:5144000 NCBI chr22:2,914,960...2,962,517
Ensembl chr22:2,917,514...2,918,551
JBrowse link
G FANCC FA complementation group C ISO DNA:haplotype::rs4647416(human) RGD PMID:21670957 RGD:11045795 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain susceptibility ISO RGD PMID:25975240 RGD:11074090 NCBI chr12:2,151,409...2,164,564 JBrowse link
G IL4 interleukin 4 susceptibility ISO DNA:SNPs:promoter,5'UTR,intron:multiple RGD PMID:20921925 RGD:11528633 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G LTC4S leukotriene C4 synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:9393345 PMID:9466979 PMID:10970818 PMID:20485159 NCBI chr11:1,893,927...1,897,028
Ensembl chr11:1,894,380...1,897,752
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16502481 NCBI chr21:50,439,133...50,456,785
Ensembl chr21:50,450,024...50,456,785
JBrowse link
G POSTN periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18391768 NCBI chr25:3,167,319...3,208,970
Ensembl chr25:3,167,359...3,208,411
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr18:55,426,632...55,431,916
Ensembl chr18:55,429,308...55,430,510
JBrowse link
G PTGER2 prostaglandin E receptor 2 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15496426 NCBI chr 8:28,523,318...28,536,936
Ensembl chr 8:28,522,681...28,536,922
JBrowse link
G PTGIR prostaglandin I2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20485159 NCBI chr 1:109,275,198...109,279,463
Ensembl chr 1:109,274,988...109,277,584
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:mast cell
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9487340 PMID:16502481 PMID:20485159 RGD:5143936 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO RGD PMID:21796142 RGD:5147839 NCBI chr12:2,407,512...2,417,469
Ensembl chr12:2,378,126...2,432,303
JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, aspirin-induced, susceptibility to ClinVar PMID:15806396 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261
JBrowse link
G TBXA2R thromboxane A2 receptor susceptibility ISO DNA:polymorphism: :795T>C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15898979 PMID:16502481 PMID:20485159 RGD:11059537 NCBI chr20:55,819,866...55,829,395
Ensembl chr20:55,824,410...55,828,980
JBrowse link
asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO protein:increased expression:blood, lymphocyte RGD PMID:19484671 RGD:4890020 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 ISO RGD PMID:18931056 RGD:5128825 NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase no_association ISO RGD PMID:16008680 PMID:19771478 RGD:5128831 RGD:5128835 NCBI chr 9:49,746,749...49,758,317
Ensembl chr 9:49,748,693...49,758,479
JBrowse link
G ACE angiotensin I converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:19383228 PMID:19484664 RGD:4140913 RGD:4140919 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO DNA:hypermethylation:promoter RGD PMID:19221603 RGD:13831295 NCBI chr37:28,882,264...28,929,451
Ensembl chr37:28,864,147...28,938,866
JBrowse link
G ADA adenosine deaminase susceptibility ISO DNA:polymorphisms (human) RGD PMID:16754522 RGD:5128848 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 disease_progression
susceptibility
no_association
ISO mRNA:increased expression:bronchus
mRNA:increased expression:lung
DNA:SNPs (human)
DNA:polymorphism: :p.M764T (human)
DNA:SNPs:introns,exon:7575G>A, 11188A>T, 12433T>C (human)
DNA:SNPs: :multiple (human)
RGD PMID:16893396 PMID:17339047 PMID:17961406 PMID:18778489 PMID:19635592 More... RGD:4145359 RGD:4145360 RGD:4145378 RGD:4145379 RGD:4145380 RGD:4145382 NCBI chr24:17,668,377...17,682,217
Ensembl chr24:17,668,500...17,681,209
JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 severity ISO mRNA:increased expression:respiratory tract
mRNA:increased expression:bronchus
RGD PMID:17339047 PMID:19373511 PMID:20194813 RGD:4145380 RGD:5128872 RGD:5128878 NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747
JBrowse link
G ADCY2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr34:6,139,931...6,527,677
Ensembl chr34:6,140,276...6,527,677
JBrowse link
G ADCYAP1R1 ADCYAP receptor type I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21059121 NCBI chr14:43,707,683...43,761,166
Ensembl chr14:43,701,745...43,756,571
JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide susceptibility ISO protein:increased expression:respiratory system fluid/secretion
DNA:SNPs: :rs1154404, rs28730619 (human)
RGD PMID:15919956 PMID:17543375 PMID:19395503 PMID:19514054 RGD:5128882 RGD:5128890 RGD:5128891 RGD:5128892 NCBI chr32:21,249,459...21,261,130
Ensembl chr32:21,249,739...21,265,048
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844
JBrowse link
G ADORA1 adenosine A1 receptor ISO protein:increased expression:bronchus
DNA:SNPs: :1405C>T (human)
RGD PMID:17959644 PMID:19019667 PMID:20400685 RGD:4145444 RGD:4890386 RGD:5129097 NCBI chr 7:44,819...74,217
Ensembl chr 7:44,820...73,051
JBrowse link
G ADORA2A adenosine A2a receptor ISO DNA:SNP (human)
mRNA:decreased expression:aorta
RGD PMID:16339780 PMID:17293374 PMID:18310516 PMID:19019667 RGD:4890366 RGD:4890380 RGD:4890385 RGD:4890386 NCBI chr26:28,141,076...28,150,600
Ensembl chr26:28,141,076...28,150,598
JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility ISO ClinVar Annotator: match by term: Beta-2-adrenoreceptor agonist, reduced response to OMIM
ClinVar
PMID:8383511 PMID:15284533 PMID:16596417 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment
onset
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:lung (rat)
RGD
CTD
PMID:21920897 PMID:23304218 PMID:33075463 RGD:6767554 RGD:7244279 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129
JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:19080339 RGD:5147457 NCBI chr23:43,569,658...43,617,113
Ensembl chr23:43,614,035...43,616,238
JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO mRNA, protein:increased expression:lung RGD PMID:19080339 RGD:5147457 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:9600491 PMID:11506308 NCBI chr26:9,319,109...9,361,021 JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO protein:increased expression:lung RGD PMID:18692885 PMID:19628725 RGD:5509605 RGD:5509784 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase susceptibility
treatment
no_association
severity
ISO mRNA:increased expression:blood, leukocyte
DNA:polymorphism:cds:p.E254K (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)
protein:increased expression:lung
DNA:repeat:promoter (human)
OMIM
RGD
CTD
PMID:8879219 PMID:9642160 PMID:10369259 PMID:11035107 PMID:12911785 More... RGD:4890407 RGD:4890408 RGD:4890410 RGD:4890413 RGD:4890415 RGD:4890422 RGD:5147462 RGD:5147465 RGD:5147467 RGD:734557 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein no_association
susceptibility
ISO DNA:repeat:promoter:-169(A)21 (human)
mRNA:increased expression:blood, leukocyte
DNA:substitution, repeat:promoter:-336G>A, -169(A)19-23 (human)
DNA:polymorphism:promoter (human)
protein:increased expression:lung
DNA:SNP: :rs10507391 (human)
DNA:SNPs (human)
DNA:polymorphisms:intron:IVS2+12C>A, IVS2+105T>C (human)
RGD PMID:8879219 PMID:9642160 PMID:10527888 PMID:11035107 PMID:12911785 More... RGD:4890405 RGD:4890407 RGD:4890409 RGD:4890422 RGD:5147462 RGD:5147464 RGD:5147465 RGD:5147466 RGD:5147467 NCBI chr25:9,320,868...9,351,056
Ensembl chr25:9,320,864...9,351,836
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:serum RGD PMID:14621078 RGD:6904149 NCBI chr11:68,338,644...68,353,366
Ensembl chr11:68,338,389...68,351,994
JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:22092555 RGD:7421657 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15696081 NCBI chr13:62,925,761...62,936,753
Ensembl chr13:62,926,301...62,936,738
JBrowse link
G ARG1 arginase 1 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:lung, mononuclear cell (human)
DNA:SNP: :rs2781667 (human)
mRNA:increased expression:lung (mouse)
CTD
RGD
PMID:12813022 PMID:19281908 PMID:19800904 PMID:20124949 RGD:4143187 RGD:5129205 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305
JBrowse link
G ARG2 arginase 2 severity
susceptibility
ISO DNA:SNP: :rs3742879, rs17249437 (human)
DNA:SNPs (human)
mRNA:increased expression:lung (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12813022 PMID:16387594 PMID:19281908 PMID:20124949 RGD:4143187 RGD:5129205 RGD:5129207 NCBI chr 8:41,588,051...41,619,406
Ensembl chr 8:41,588,150...41,619,402
JBrowse link
G B9D2 B9 domain containing 2 onset
no_association
ISO DNA:SNP: :-509C>T (human)
mRNA:increased expression:lung
DNA:SNP:cds:915G>C (human)
DNA:polymorphism: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
DNA:polymorphisms: :multiple (human)
DNA:SNPs:promoter, exon:multiple (human)
RGD
CTD
PMID:16365456 PMID:17673695 PMID:18366906 PMID:18711258 PMID:19046298 More... RGD:4143443 RGD:4145113 RGD:4145132 RGD:4145139 RGD:4145142 RGD:4145143 RGD:4145144 RGD:4145280 RGD:4145295 RGD:4145297 RGD:4145299 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18357729 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BDKRB2 bradykinin receptor B2 onset ISO protein:increased expression:blood, eosinophil
DNA:polymorphism:exon (human)
RGD PMID:8856156 PMID:11517947 PMID:14727005 PMID:19038786 RGD:4890454 RGD:4890456 RGD:4891028 RGD:4891042 NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407
JBrowse link
G BDNF brain derived neurotrophic factor severity
susceptibility
ISO protein:decreased expression:blood, eosinophil
protein:increased expression:plasma
DNA:SNP,haplotypes: :rs10767664,rs12273539,rs962369(human)
DNA:polymorphisms: :p.V66M (rs6265) (human)
DNA:polymorphisms: :p.V66M, -270C>T (human)
RGD PMID:11737043 PMID:12752594 PMID:17584309 PMID:19895626 PMID:20874832 More... RGD:4891063 RGD:4891067 RGD:4891117 RGD:4891122 RGD:4891123 RGD:8655967 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:8429434 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO protein:decreased expression:bronchus RGD PMID:18292470 RGD:5129470 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G C3 complement C3 severity ISO Interaction with IL4RA
DNA:SNPs: :multiple (human)
DNA:SNP:intron:rs11569562 (human)
protein:increased expression:serum
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :4896C>T (human)
RGD PMID:11591733 PMID:15278436 PMID:16355111 PMID:18566738 PMID:20395963 More... RGD:5129501 RGD:5129505 RGD:5129512 RGD:5129517 RGD:5129519 RGD:5129537 RGD:5129538 RGD:5129681 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G C3AR1 complement C3a receptor 1 severity ISO mRNA:increased expression:lung
protein:increased expression:lung, leukocyte
RGD PMID:15278436 PMID:15940127 PMID:17544263 PMID:20045013 PMID:20802484 RGD:5129512 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5129686 NCBI chr27:37,431,745...37,439,858
Ensembl chr27:37,433,792...37,435,246
JBrowse link
G C5 complement C5 severity ISO mRNA:decreased expression:lung RGD PMID:10973279 PMID:11591795 PMID:15278436 PMID:20143644 PMID:20802484 RGD:1600651 RGD:5129512 RGD:5129681 RGD:5129706 RGD:5130158 NCBI chr11:73,953,727...74,029,919
Ensembl chr11:73,953,727...74,029,851
JBrowse link
G C5AR1 complement C5a receptor 1 severity ISO protein:increased expression:lung, leukocyte
protein:increased expression:respiratory tract
RGD PMID:15940127 PMID:16511606 PMID:17544263 PMID:20802484 RGD:5129560 RGD:5129561 RGD:5129681 RGD:5130166 NCBI chr 1:108,659,637...108,704,217
Ensembl chr 1:108,659,637...108,675,401
JBrowse link
G CARD11 caspase recruitment domain family member 11 susceptibility ISO ClinVar Annotator: match by term: Asthma RGD
ClinVar
PMID:16751370 PMID:18323416 PMID:23129749 PMID:25741868 PMID:28492532 RGD:11100037 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094
JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA:decreased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr20:50,328,466...50,371,845
Ensembl chr20:50,331,030...50,348,195
JBrowse link
G CAT catalase severity ISO protein:decreased activity
DNA:polymorphism:promoter:-21A>T (human)
protein:decreased activity:respiratory system fluid/secretion
protein:increased expression:erythrocyte
DNA:polymorphism:promoter:-262C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16622028 PMID:18048809 PMID:19373626 PMID:19475625 RGD:5130751 RGD:5130753 RGD:5130856 RGD:5130867 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
JBrowse link
G CCL1 C-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20455898 RGD:4891420 NCBI chr 9:38,931,895...38,936,969
Ensembl chr 9:38,933,514...38,961,187
JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO mRNA:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:11160256 PMID:15947487 PMID:15993846 PMID:20074456 PMID:20237293 RGD:2306304 RGD:4145486 RGD:4145487 RGD:4145513 RGD:4145603 NCBI chr 2:59,001,463...59,014,347
Ensembl chr 2:59,001,464...59,005,230
JBrowse link
G CCL19 C-C motif chemokine ligand 19 ISO protein:increased expression:bronchus submucosa, mast cell RGD PMID:16959919 RGD:5130911 NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment
severity
ISO CTD Direct Evidence: marker/mechanism
DNA:haplotype::-2518A>G (human)
mRNA:increased expression:lung (mouse)
protein:increased expression:lung
protein:increased expression:serum
CTD
RGD
PMID:12055264 PMID:17964702 PMID:19373627 PMID:20205697 PMID:23454776 More... RGD:11528569 RGD:11528570 RGD:2307055 RGD:4145509 RGD:4891466 RGD:8551842 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO protein:increased expression:respiratory system fluid/secretion
associated with Allergic Rhinitis;protein:increased expression:serum
RGD PMID:18422729 PMID:22469443 RGD:7483597 RGD:7483618 NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO mRNA:increased expression:lung
mRNA, protein:increased expression:respiratory system mucosa, respiratory system fluid/secretion
protein:increased expression:respiratory system fluid/secretion
RGD PMID:10384142 PMID:15993846 PMID:18316417 PMID:18684970 RGD:2306304 RGD:4145489 RGD:4891474 RGD:4891475 NCBI chr 2:59,039,650...59,045,519
Ensembl chr 2:59,040,539...59,045,625
JBrowse link
G CCL24 C-C motif chemokine ligand 24 susceptibility ISO protein:increased expression:plasma
DNA:SNPs: :304C>A, 1272A>G (human)
protein:increased expression:respiratory system fluid/secretion
DNA:SNP: :1265A>G (human)
DNA:SNPs: :179T>C, 275C>T (human)
RGD PMID:12761043 PMID:12952266 PMID:15207712 PMID:16304252 PMID:17060636 More... RGD:4891483 RGD:4891484 RGD:4891485 RGD:4891495 RGD:4891496 RGD:5130930 RGD:5130932 NCBI chr 6:7,166,165...7,179,606
Ensembl chr 6:7,166,479...7,180,051
JBrowse link
G CCL26 C-C motif chemokine ligand 26 treatment ISO protein:increased expression:plasma
DNA:SNPs: :77C>T, 716A>G, 1579G>A (human)
DNA:SNPs: :77C>T, 2497T>G (human)
RGD PMID:15207712 PMID:16304252 PMID:18712274 PMID:25399816 PMID:25530546 RGD:11081163 RGD:11087575 RGD:4891483 RGD:4891495 RGD:5130930 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726
JBrowse link
G CCL27 C-C motif chemokine ligand 27 ISO RGD PMID:19541356 RGD:5130899 NCBI chr11:51,334,870...51,338,752
Ensembl chr11:51,334,778...51,335,591
JBrowse link
G CCL28 C-C motif chemokine ligand 28 ISO mRNA:increased expression:lung (mouse) RGD PMID:16290206 RGD:4892195 NCBI chr 4:66,567,139...66,597,310
Ensembl chr 4:66,566,989...66,597,459
JBrowse link
G CCL4 chemokine (C-C motif) ligand 4 ISO RGD PMID:18774390 RGD:5130915 NCBI chr 9:37,681,342...37,682,691
Ensembl chr 9:37,676,966...37,710,209
JBrowse link
G CCL5 C-C motif chemokine ligand 5 susceptibility ISO DNA:transition:5' utr:-403G>A (human)
protein:increased expression:smooth muscle cell
protein:increased expression:lung, secretion (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8534483 PMID:18208670 PMID:20092989 PMID:20430255 RGD:2307112 RGD:4891381 RGD:4891430 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO Promoter polymorphism RGD PMID:19965981 PMID:21388664 RGD:5130979 RGD:5130983 NCBI chr 9:38,994,638...38,996,103
Ensembl chr 9:38,993,911...39,010,483
JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 severity ISO mRNA:increased expression:lung
associated with Respiratory Syncytial Virus Infections
RGD PMID:15593301 PMID:15654816 RGD:5688158 RGD:5688159 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958
JBrowse link
G CCR2 C-C motif chemokine receptor 2 susceptibility ISO DNA:SNP:cds:p.V64I (human)
protein:increased expression:lung, dendritic cell (mouse)
DNA:haplotype:cds:p.V64I(human)
RGD PMID:17298432 PMID:19917684 PMID:23454776 RGD:4145110 RGD:8549811 RGD:8551842 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO protein:increased expression:respiratory system fluid/secretion, neutrophil
DNA:SNP:exon:51T>C (human)
RGD PMID:16978084 PMID:17145927 PMID:18699933 PMID:19017998 PMID:19657453 More... RGD:1601020 RGD:4145618 RGD:4145623 RGD:4145632 RGD:4145633 RGD:4145638 RGD:4145646 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217
JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr23:3,844,072...3,847,770
Ensembl chr23:3,844,173...3,845,255
JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association ISO mRNA:increased expression:lung (mouse)
DNA:polymorphism, frameshift mutation: :-59029G>A, p.S185_T195del (rs333) (human)
protein:decreased expression:blood, lymphocyte (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
RGD PMID:15256090 PMID:16474097 PMID:18094012 PMID:20220260 PMID:23454776 RGD:4145638 RGD:4892088 RGD:4892093 RGD:4892108 RGD:8551842 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952
JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr 1:54,932,798...54,960,646
Ensembl chr 1:54,932,690...54,959,740
JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISO protein:increased expression:lung, dendritic cell (mouse) RGD PMID:19917684 RGD:8549811 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656
JBrowse link
G CCR8 C-C motif chemokine receptor 8 ISO mRNA:increased expression:lung RGD PMID:15993846 RGD:2306304 NCBI chr23:9,013,242...9,019,513
Ensembl chr23:9,018,060...9,018,589
JBrowse link
G CCR9 C-C motif chemokine receptor 9 ISO mRNA, protein:increased expression:blood, mature NK T cell RGD PMID:16210593 RGD:5130925 NCBI chr20:42,607,024...42,616,823
Ensembl chr20:42,607,024...42,616,823
JBrowse link
G CD14 CD14 molecule severity
no_association
susceptibility
ISO protein:increased expression:serum
protein:increased expression:serum|DNA:polymorphism:promoter:c. -159C>T (human)
DNA:polymorphism:promoter:c. -260C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :
RGD
CTD
PMID:15741437 PMID:15940135 PMID:16387800 PMID:17607003 PMID:18312481 More... RGD:4144208 RGD:4144228 RGD:4144813 RGD:4144814 RGD:4144815 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G CD1D CD1d molecule susceptibility ISO associated with fasciolopsiasis RGD PMID:20304473 RGD:4140417 NCBI chr38:23,489,169...23,491,712 JBrowse link
G CD209 CD209 molecule ISO RGD PMID:21471959 RGD:5131188 NCBI chr20:52,517,759...52,542,085
Ensembl chr20:52,518,036...52,520,942
JBrowse link
G CD274 CD274 molecule treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522
JBrowse link
G CD28 CD28 molecule ISO RGD PMID:21356099 RGD:5131612 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:19159017 PMID:19220210 PMID:20205594 PMID:20941750 RGD:4144188 RGD:4892277 RGD:5132272 RGD:8547792 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CD40LG CD40 ligand severity ISO RGD PMID:9502776 RGD:11352238 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:21051864 PMID:21352203 PMID:21440530 RGD:5132619 RGD:5132620 RGD:5132621 NCBI chr33:23,177,136...23,208,421
Ensembl chr33:23,177,138...23,201,380
JBrowse link
G CD86 CD86 molecule treatment ISO protein:increased expression:blood, B cell (human)
protein:increased expression:lung, dendritic cell (rat)
DNA:snp:exon:p.I179V rs2681417 (human)
protein:increased expression:lung, alveolar macrophage (mouse)
RGD PMID:9449507 PMID:9551945 PMID:17513529 PMID:20668438 PMID:20941750 More... RGD:11354965 RGD:4892199 RGD:4892202 RGD:4892277 RGD:4892280 RGD:4892555 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G CDH1 cadherin 1 ISO RGD PMID:21540309 RGD:5132878 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G CDHR3 cadherin related family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr18:14,437,083...14,497,711
Ensembl chr18:14,437,751...14,497,646
JBrowse link
G CFTR CF transmembrane conductance regulator susceptibility ISO DNA:deletion: :p.F508del(human) RGD PMID:20298391 RGD:4140387 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977
JBrowse link
G CHAT choline O-acetyltransferase ISO Protein:decreased expression:lung epithelium RGD PMID:17328924 RGD:5686690 NCBI chr28:1,480,364...1,528,858
Ensembl chr28:1,482,202...1,528,776
JBrowse link
G CHI3L1 chitinase 3 like 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 7 OMIM
ClinVar
PMID:18403759 NCBI chr 7:25,620...32,954
Ensembl chr 7:26,316...33,427
JBrowse link
G CHIA chitinase acidic no_association ISO DNA:snps:5' utr, cds:multiple (human)
DNA:snps:multiple (human)
mRNA:increased expression:lung, epithelial cell (human)
mRNA:increased expression:lung (mouse)
RGD PMID:14734765 PMID:15192232 PMID:16179638 PMID:19548841 PMID:20226308 RGD:4985150 RGD:4990463 RGD:4996473 RGD:5024921 RGD:5024922 NCBI chr 6:40,754,906...40,766,779
Ensembl chr 6:40,754,993...40,766,891
JBrowse link
G CHML CHM like Rab escort protein ISO RGD PMID:18343558 RGD:5133238 NCBI chr 7:33,027,051...33,040,711 JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 ISO RGD PMID:16931638 RGD:5133416 NCBI chr18:53,783,938...53,797,750
Ensembl chr18:53,795,326...53,796,708
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO DNA:SNP: :rs6962027 (human) RGD PMID:19308904 RGD:5509586 NCBI chr16:11,515,727...11,665,651
Ensembl chr16:11,515,426...11,664,977
JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 severity ISO RGD PMID:18348887 PMID:20394512 RGD:5133437 RGD:5133438 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:21496385 RGD:5133703 NCBI chr28:12,964,670...13,001,557
Ensembl chr28:12,965,479...13,001,512
JBrowse link
G CLCA1 chloride channel accessory 1 susceptibility ISO DNA:SNPs (human) RGD PMID:11296262 PMID:15318163 PMID:17898169 RGD:4145653 RGD:4145656 RGD:4145661 NCBI chr 6:61,620,755...61,650,111
Ensembl chr 6:61,620,995...61,650,083
JBrowse link
G CLDN18 claudin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27215490 NCBI chr23:34,229,115...34,257,431
Ensembl chr23:34,228,992...34,255,650
JBrowse link
G CMA1 chymase 1 severity
no_association
susceptibility
ISO protein:increased expression:lung epithelium, mast cell (human)
DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human)
DNA:duplications:3' utr:g.*254-?dupTG, dupGA (human)
RGD PMID:15248847 PMID:15924217 PMID:20813890 RGD:1625396 RGD:1625397 RGD:5128804 NCBI chr 8:4,438,244...4,441,189
Ensembl chr 8:4,438,244...4,441,189
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO DNA:SNPs: :rs1876828, rs242939, rs242941 (human)
DNA:SNP: :RS242941 (human)
RGD PMID:16113459 PMID:19663668 RGD:5147485 RGD:5147488 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO DNA:SNPs: :multiple (human) RGD PMID:18408560 RGD:5130938 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142
JBrowse link
G CRP C-reactive protein ISO protein:increased expression:serum RGD PMID:21140796 RGD:5131288 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166
JBrowse link
G CSF2 colony stimulating factor 2 severity ISO protein:increased expression:lung
protein:increased expression:sputum
RGD PMID:9717963 PMID:19213775 PMID:20405019 RGD:10449521 RGD:5131473 RGD:5131476 NCBI chr11:20,342,880...20,346,959
Ensembl chr11:20,344,648...20,346,959
JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta ISO RGD PMID:17145927 RGD:1601020 NCBI chr10:27,541,645...27,566,907
Ensembl chr10:27,541,647...27,567,278
JBrowse link
G CSF3 colony stimulating factor 3 ISO protein:increased expression:lung RGD PMID:20405019 PMID:21396376 RGD:5131473 RGD:5133731 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 severity
treatment
no_association
ISO DNA:SNPs: :multiple (human)
DNA:polymorphisms:promoter, exon:-318C>T 49A>G (human)
DNA:polymorphism:promoter:-318C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3087243 (human)
DNA:SNPs:promoter, exon:-1147C>T, -318C>T, 49A>G (human)
protein:increased expression:serum
RGD
CTD
PMID:11726402 PMID:12114354 PMID:12956753 PMID:15316504 PMID:15871446 More... RGD:11344922 RGD:4891510 RGD:4891514 RGD:4891516 RGD:4891517 RGD:4891519 RGD:4891521 RGD:4891522 RGD:4891526 RGD:4891527 RGD:4891528 RGD:4891529 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G CTNNA3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19187332 NCBI chr 4:17,364,121...19,035,836
Ensembl chr 4:17,372,245...19,017,093
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:plasma RGD PMID:14657873 RGD:4891906 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 no_association ISO DNA:SNPs: :p.V249I, rs2669849 (human)
DNA:polymorphisms: :p.V249I, p.T280M (human)
RGD PMID:17082760 PMID:17505143 PMID:21037587 RGD:4891882 RGD:4891895 RGD:4891904 NCBI chr23:8,937,069...8,954,738
Ensembl chr23:8,938,906...8,952,808
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO protein:decreased expression:plasma RGD PMID:11994485 PMID:16602032 PMID:17302903 RGD:5135439 RGD:5135452 RGD:5135457 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 NCBI chr11:23,598,640...23,606,850
Ensembl chr11:23,599,645...23,606,823
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 susceptibility
severity
ISO protein:decreased expression:respiratory system fluid/secretion, T cell
DNA:SNP:intron:IVS1+234G>A (human)
RGD PMID:16043121 PMID:16548899 PMID:17641057 PMID:18094012 RGD:4892088 RGD:5135484 RGD:5143932 RGD:5143934 NCBI chr  X:55,882,433...55,884,582
Ensembl chr  X:55,882,433...55,884,582
JBrowse link
G CYBA cytochrome b-245 alpha chain susceptibility ISO DNA:SNPs: :-930A>G, 242C>T, 640A>G (human)
DNA:polymorphism: :-930A>G (human)
RGD PMID:18716406 PMID:19459419 RGD:4311041 RGD:4772770 NCBI chr 5:64,692,865...64,701,056
Ensembl chr 5:64,692,123...64,704,893
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA, protein:increased expression, decreased activity:lung RGD PMID:12415424 RGD:4892074 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
JBrowse link
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 ISO DNA:polymorphism: :1934G>A (human) RGD PMID:19575027 RGD:5143944 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO mRNA:decreased expression:leukocyte
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17081494 PMID:20514434 PMID:28807506 RGD:4892076 RGD:4892220 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 no_association
severity
ISO DNA:SNP: :927T>C (human)
DNA:SNPs:promoter, exon:multiple (human)
DNA:SNPs:promoter:-634C>T, -475A>C, -336A>G (human)
mRNA, protein:increased expression:respiratory system mucosa
RGD PMID:8087328 PMID:11591188 PMID:16123393 PMID:16387808 PMID:16630147 More... RGD:4781449 RGD:4781742 RGD:4782072 RGD:4784257 RGD:4843543 RGD:4847129 RGD:4848936 RGD:4888514 RGD:4889116 NCBI chr  X:60,462,290...60,513,155
Ensembl chr  X:60,463,526...60,464,548
JBrowse link
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO DNA:polymorphism: :-1220A>C (human)
DNA:polymorphism: :601A>G (human)
RGD PMID:15454733 PMID:15475736 RGD:5144002 RGD:5144003 NCBI chr22:2,914,960...2,962,517
Ensembl chr22:2,917,514...2,918,551
JBrowse link
G DCN decorin ISO RGD PMID:16387756 RGD:2311423 NCBI chr15:31,833,492...31,887,699
Ensembl chr15:31,833,746...31,877,417
JBrowse link
G DEFB1 defensin beta 1 susceptibility ISO DNA:SNP: :-1816 T>C (human)
DNA:SNPs:5' utr:g.-52G>A, g.-44C>G, g.-20G>A (human)
RGD PMID:15696078 PMID:16435024 RGD:4892254 RGD:4892263 NCBI chr16:58,871,018...58,881,592
Ensembl chr16:58,871,018...58,881,592
JBrowse link
G DLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility ISO DNA:polymorphism: :rs3916765(human) RGD PMID:20159242 RGD:13506913 NCBI chr12:2,221,181...2,227,600
Ensembl chr12:2,221,137...2,227,600
JBrowse link
G DLA-DRA MHC class II DR alpha chain susceptibility ISO DNA:polymorphisms: : RGD PMID:20159242 RGD:13506913 NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975
JBrowse link
G DLA88 MHC class I DLA-88 susceptibility ISO DNA:polymorphism: RGD PMID:28380482 RGD:13506910 NCBI chr12:892,442...895,691
Ensembl chr12:892,388...1,021,690
JBrowse link
G DNAH5 dynein axonemal heavy chain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr34:816,088...1,040,052
Ensembl chr34:805,455...1,038,273
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism
DNA,mRNA:hypermethylation,decreased expression:promoter,respiratory tract:
CTD
RGD
PMID:23196709 PMID:23423710 RGD:9588646 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DPP10 dipeptidyl peptidase like 10 ISO DNA:SNP:exon (human)
protein:increased expression:bronchus
DNA:SNP: :rs10208402 (human)
DNA:SNPs (human)
RGD PMID:14566338 PMID:17967935 PMID:19672052 PMID:21103062 RGD:4889866 RGD:4892275 RGD:4892276 RGD:4892278 NCBI chr19:33,432,091...34,707,133
Ensembl chr19:33,434,154...34,706,758
JBrowse link
G EBI3 Epstein-Barr virus induced 3 ISO RGD PMID:21255010 RGD:5128488 NCBI chr20:55,382,975...55,391,252
Ensembl chr20:55,383,247...55,390,336
JBrowse link
G EDN1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism
Severe Persistent Allergic Asthma; protein:increased secretion:lung (human)
DNA:transition:intron:g.4124T>C (human)
CTD
RGD
PMID:11668616 PMID:16981460 PMID:20588001 RGD:4144869 RGD:4144895 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383
JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:17448648 PMID:18632188 RGD:4892288 RGD:4892322 NCBI chr15:45,823,472...45,878,527
Ensembl chr15:45,823,560...45,876,463
JBrowse link
G EDNRB endothelin receptor type B ISO mRNA:increased expression:bronchus, smooth muscle cell
DNA:polymorphism (human)
RGD PMID:15245576 PMID:17470272 PMID:18632188 RGD:4892288 RGD:4892321 RGD:4892324 NCBI chr22:31,415,324...31,438,772
Ensembl chr22:31,417,308...31,437,587
JBrowse link
G EGFR epidermal growth factor receptor severity ISO protein:increased expression:lung epithelium (rat)
protein:increased expression:lung epithelium (mouse)
protein:increased expression:bronchial epithelium (human)
RGD PMID:12580917 PMID:19954006 PMID:21072743 PMID:21224214 RGD:5131468 RGD:5131633 RGD:5131642 RGD:5131870 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G EGR1 early growth response 1 ISO DNA:snp:5' utr:g.-4071A>G rs7729723 (human)
mRNA:increased expression:bronchoalveolar lavage cell (human)
RGD PMID:11254538 PMID:18507785 PMID:18774390 RGD:5130915 RGD:5131985 RGD:5131993 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575
JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 no_association ISO RGD PMID:11281413 PMID:12774215 RGD:5129157 RGD:5129158 NCBI chr11:64,035,667...64,094,402
Ensembl chr11:64,037,506...64,093,819
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility ISO DNA:SNPs:exons:p.Y113H (rs1051740), p.H139R (rs2234922) (human) RGD PMID:17711870 RGD:4889407 NCBI chr 7:38,964,319...39,004,902
Ensembl chr 7:38,964,338...38,999,238
JBrowse link
G EPX eosinophil peroxidase severity
disease_progression
ISO protein:increased activity:sputum,nasal,pharyngeal mucosa RGD PMID:12199967 PMID:20813885 PMID:26645423 RGD:11574908 RGD:13506891 RGD:13506892 NCBI chr 9:32,855,568...32,865,445
Ensembl chr 9:32,855,507...32,865,022
JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:18375789 RGD:8694127 NCBI chr 8:38,645,917...38,715,347
Ensembl chr 8:38,645,430...38,702,691
JBrowse link
G F2 coagulation factor II, thrombin ISO associated with Rhinosinusitis, associated with Nasal Polyps;protein:increased expression:nasal mucus
protein:increased expression:plasma
RGD PMID:21658190 PMID:21711961 RGD:5147753 RGD:5147783 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G F2RL1 F2R like trypsin receptor 1 ISO RGD PMID:19864598 RGD:4892589 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180
JBrowse link
G F7 coagulation factor VII treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024
JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:eosinophil RGD PMID:16337971 RGD:1600350 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FCER1A Fc epsilon receptor Ia severity ISO Asthma symptoms persistent despite steroids
Fatal asthma subjects
RGD PMID:20937062 PMID:21388666 RGD:5128711 RGD:5128717 NCBI chr38:22,683,478...22,688,842
Ensembl chr38:22,683,477...22,690,763
JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb ISO RGD PMID:20179765 RGD:11344929 NCBI chr38:20,980,777...20,994,403 JBrowse link
G FGA fibrinogen alpha chain treatment ISO RGD PMID:24523826 RGD:11040539 NCBI chr15:52,238,305...52,247,017
Ensembl chr15:52,236,198...52,246,975
JBrowse link
G FKBP5 FKBP prolyl isomerase 5 ISO ClinVar Annotator: match by term: Asthma ClinVar NCBI chr12:4,724,668...4,833,691
Ensembl chr12:4,727,497...4,833,323
JBrowse link
G FOXP3 forkhead box P3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27633092 PMID:27965764 PMID:28944907 PMID:29317916 RGD:38548920 RGD:38549365 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G GATA3 GATA binding protein 3 ISO RGD PMID:9949310 PMID:18186587 RGD:5128802 RGD:5128803 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G GC GC vitamin D binding protein ISO protein, mRNA:increased expression:bronchoalveolar lavage fluid: RGD PMID:21169467 RGD:5509920 NCBI chr13:60,795,305...60,828,038
Ensembl chr13:60,795,305...60,827,929
JBrowse link
G GSDMB gasdermin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr 9:22,604,358...22,616,540 JBrowse link
G GSTO2 glutathione S-transferase omega 2 susceptibility ISO DNA:polymorphism:exon:p. N142D (human) RGD PMID:20374258 RGD:5490988 NCBI chr28:16,580,250...16,604,977
Ensembl chr28:16,586,777...16,604,976
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility
severity
no_association
disease_progression
ISO DNA:SNP: :p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs:intron,exon:(rs749174), (rs1138272)(human)
DNA:polymorphism:exon:p.I105V (rs1695) (human)
DNA:SNPs:exons:p.I105V (rs1695), A114V (rs1138272) (human)
DNA:SNPs: :p.I105V, p.A114V (human)
DNA:polymorphism:exon:p.I105V (human)
RGD
CTD
PMID:10806136 PMID:11994713 PMID:15693909 PMID:16176403 PMID:16870661 More... RGD:4140946 RGD:4140947 RGD:4140951 RGD:4142519 RGD:4142526 RGD:5490985 RGD:5490991 RGD:5490999 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO RGD PMID:20628202 RGD:5128851 NCBI chr 4:53,012,223...53,066,611
Ensembl chr 4:53,046,970...53,128,952
Ensembl chr 4:53,046,970...53,128,952
JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 ISO RGD PMID:17517968 RGD:5135525 NCBI chr 4:53,018,990...53,032,035
Ensembl chr 4:53,012,234...53,033,393
JBrowse link
G HDAC2 histone deacetylase 2 ISO mRNA:decreased expression:macrophage: RGD PMID:20538962 RGD:9590321 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578
JBrowse link
G HDC histidine decarboxylase ISO associated with Rhinitis;DNA:SNP: :p.E644D (rs2073440) (human) RGD PMID:20608921 RGD:5128884 NCBI chr30:16,201,222...16,223,452
Ensembl chr30:16,201,589...16,223,662
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:18160846 RGD:10402541 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain no_association
susceptibility
severity
ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
DNA:polymorphisms: :
CTD
RGD
PMID:10051703 PMID:16792590 PMID:19439981 PMID:19528258 PMID:20159242 More... RGD:1331670 RGD:13506906 RGD:13506913 RGD:4144181 RGD:4144196 RGD:5147607 RGD:5147663 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20084838 RGD:5508450 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294
JBrowse link
G HMOX1 heme oxygenase 1 severity ISO mRNA;protein:increased expression:Leukocytes, Mononuclear
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16196283 PMID:18048809 PMID:20596599 RGD:4145403 RGD:4145408 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G HNMT histamine N-methyltransferase susceptibility
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to OMIM
ClinVar
RGD
PMID:10752634 PMID:10803682 PMID:15693910 PMID:16205835 PMID:17651147 RGD:5128885 RGD:5128887 RGD:5128888 NCBI chr19:40,656,266...40,702,498
Ensembl chr19:40,655,161...40,702,218
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932298 NCBI chr 5:81,966,397...81,970,301
Ensembl chr 5:81,966,937...81,968,991
JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25322896 NCBI chr22:4,453,715...4,510,934
Ensembl chr22:4,453,715...4,511,037
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO mRNA:increased expression:aorta (mouse)
protein:increased expression:lung, serum (rat)
CTD Direct Evidence: marker/mechanism
protein:increased secretion:lung (human)
RGD
CTD
PMID:17014439 PMID:20205697 PMID:20400685 PMID:20953388 PMID:25003170 RGD:4145331 RGD:4145444 RGD:4145509 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G IFNG interferon gamma resistance
treatment
ISO protein:increased expression:sputum RGD PMID:12396623 PMID:19542437 PMID:20817868 PMID:20953328 RGD:10755706 RGD:4145525 RGD:4145651 RGD:5128479 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IFNGR1 interferon gamma receptor 1 ISO DNA: SNP: Leu467Pro RGD PMID:12851715 PMID:21737883 RGD:6480255 RGD:6480431 NCBI chr 1:29,646,776...29,669,669
Ensembl chr 1:29,647,552...29,669,578
JBrowse link
G IFNL3 interferon lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096
G IKZF3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25256354 NCBI chr 9:22,643,482...22,733,988
Ensembl chr 9:22,643,640...22,728,385
JBrowse link
G IL10 interleukin 10 treatment
susceptibility
ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma
DNA:polymorphism: :-627C>A (human)
RGD
CTD
PMID:12938145 PMID:20121766 PMID:20230687 PMID:20237464 PMID:20560982 More... RGD:11046261 RGD:4140421 RGD:4140451 RGD:4140459 RGD:4140471 RGD:4143221 RGD:5131623 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL12A interleukin 12A ISO RGD PMID:17056578 PMID:17548618 RGD:4373570 RGD:4438438 NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550
JBrowse link
G IL12B interleukin 12B susceptibility
severity
ISO DNA:polymorphisms:promoter, 3'utr:
ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphisms:introns:
DNA:polymorphism:promoter
RGD
ClinVar
PMID:12241719 PMID:15322986 PMID:16210052 RGD:1600043 RGD:4145428 RGD:4145438 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228
JBrowse link
G IL13 interleukin 13 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:cds:p.R130Q (human)
protein:increased expression:sputum
protein:increased expression:serum
DNA:polymorphism: :c.-1055C>T (human)
OMIM
ClinVar
RGD
PMID:10699178 PMID:11588017 PMID:11678850 PMID:11709756 PMID:11758895 More... RGD:4145593 RGD:4145639 RGD:4145777 RGD:4763153 RGD:4763761 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 no_association ISO DNA:polymorphism: :1050C>T (human)
mRNA:increased expression:bronchus
DNA:polymorphism: :1398A>G (human)
DNA:polymorphisms:promoter, 3' utr:-281T>G, 1365A>G (human)
RGD PMID:10686479 PMID:11714828 PMID:17006604 PMID:17392323 PMID:18480254 More... RGD:4892639 RGD:4892646 RGD:4892647 RGD:4892650 RGD:4892654 RGD:4892655 NCBI chr  X:90,925,497...90,981,855
Ensembl chr  X:90,924,801...90,979,963
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO mRNA:increased expression:bronchus
protein:increased expression:serum
RGD PMID:17885690 PMID:20383033 PMID:21462799 RGD:4892646 RGD:4892649 RGD:8549521 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798
JBrowse link
G IL15 interleukin 15 no_association ISO DNA:SNPs: :multiple (human) RGD PMID:11160248 PMID:15131572 PMID:15843549 PMID:16629787 PMID:19133918 RGD:4984421 RGD:4990462 RGD:5000757 RGD:5000758 RGD:5000760 NCBI chr19:1,339,607...1,364,762
Ensembl chr19:1,339,967...1,364,762
JBrowse link
G IL16 interleukin 16 no_association
severity
ISO associated with Rhinitis;protein:increased expression:respiratory system fluid/secretion
DNA:SNP:promoter:-295T>C (human)
protein:increased expression:serum
RGD PMID:10585533 PMID:12872394 PMID:15784111 PMID:16387589 PMID:16734115 RGD:5024928 RGD:5024930 RGD:5024934 RGD:5024935 RGD:5024937 NCBI chr 3:56,473,485...56,575,504
Ensembl chr 3:56,473,486...56,575,104
JBrowse link
G IL17A interleukin 17A susceptibility ISO mRNA,protein:increased expression:Leukocytes, Mononuclear, lung, serum
DNA:SNP:promoter:rs2275913 (human)
protein:increased expression:alveolar macrophage
protein:increased expression:sputum
RGD PMID:15730730 PMID:18060619 PMID:18941201 PMID:20351038 PMID:20437253 RGD:4839043 RGD:4888527 RGD:4889114 RGD:4889139 RGD:4889152 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL17RB interleukin 17 receptor B ISO associated with Picornaviridae Infections RGD PMID:25273095 RGD:39128256 NCBI chr20:36,135,620...36,148,923
Ensembl chr20:36,135,619...36,148,490
JBrowse link
G IL18 interleukin 18 susceptibility
severity
disease_progression
ISO DNA:SNP:promoter:c.and -137G>C (rs187238)(human)
DNA:SNP:promoter: c.-380C>G (rs5744247)(human)
DNA:SNPs:Promoter:c. -607C>A (rs1946518), -137G/C (rs187238) (human)
DNA:polymorphism: :c. -105A>C (human)
protein:increased expression:serum
RGD PMID:11174201 PMID:16433859 PMID:17767553 PMID:18200581 PMID:18826499 More... RGD:4889585 RGD:4889863 RGD:4889898 RGD:4889900 RGD:4889908 RGD:4889910 RGD:4889923 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO DNA:SNPs: :multiple (human)
DNA:SNP: :rs3771166 (human)
RGD PMID:11972614 PMID:18382474 PMID:18774397 PMID:19910030 PMID:20860503 RGD:5024942 RGD:5024945 RGD:5024946 RGD:5024947 RGD:5024948 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454
JBrowse link
G IL19 interleukin 19 ISO mRNA, protein:increased expression:lung, serum
protein:increased expression:serum
RGD PMID:15557163 RGD:5037236 NCBI chr 7:6,000,994...6,006,959
Ensembl chr 7:6,000,907...6,006,870
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:polymorphisms: : RGD PMID:18763028 RGD:4142802 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G IL1B interleukin 1 beta susceptibility ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:neutrophil
DNA:polymorphism: :-511C>T (human)
CTD
RGD
PMID:9176529 PMID:18926055 PMID:19684087 PMID:19842845 RGD:4142830 RGD:4142836 RGD:4142864 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 susceptibility
severity
ISO protein:increased expression:serum
DNA:SNP: :rs1420101 (human)
DNA:SNP: :rs10197862 (human)
DNA:SNPs:intron:rs1420089, rs1861245,rs1946131 (human)
DNA:SNP: :rs1041973 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11463601 PMID:17407196 PMID:17623648 PMID:19179489 PMID:19198610 More... RGD:5144235 RGD:5144237 RGD:5144239 RGD:5144240 RGD:5144242 RGD:5144243 RGD:5144244 RGD:5144245 NCBI chr10:40,658,191...40,732,097
Ensembl chr10:40,659,041...40,677,357
JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility
severity
ISO DNA:SNPs: :rs447713, rs3087271 (human)
DNA, protein:repeat, decreased expression (human)
protein:increased expression:plasma
DNA:SNPs: :multiple (human)
DNA:SNP: :rs2234678 (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:intron (human)
RGD
CTD
PMID:9176529 PMID:10843772 PMID:11027520 PMID:15020290 PMID:16409203 More... RGD:4142802 RGD:4142864 RGD:4143163 RGD:4143208 RGD:4143209 RGD:4143216 RGD:4143224 RGD:4143225 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329
JBrowse link
G IL2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human) RGD PMID:16333313 PMID:20926789 RGD:4889118 RGD:8663473 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G IL21 interleukin 21 ISO DNA:SNP:exon:5250C>T (human) RGD PMID:18802358 RGD:5147396 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
JBrowse link
G IL22 interleukin 22 severity
treatment
ISO mRNA:increased expression:blood, mononuclear cell
protein:increased expression:serum
RGD PMID:21297073 PMID:21535180 PMID:21998459 RGD:11046261 RGD:5147403 RGD:5147409 NCBI chr10:10,487,367...10,492,238
Ensembl chr10:10,487,262...10,492,371
JBrowse link
G IL23R interleukin 23 receptor ISO RGD PMID:19935773 RGD:5037240 NCBI chr 5:43,307,422...43,369,806
Ensembl chr 5:43,308,982...43,368,474
JBrowse link
G IL25 interleukin 25 ISO mRNA, protein:increased expression:lung RGD PMID:25273095 RGD:39128256 NCBI chr 8:3,621,268...3,624,689
Ensembl chr 8:3,618,161...3,624,043
JBrowse link
G IL27 interleukin 27 treatment
susceptibility
ISO protein:increased expression:sputum
DNA:SNP: :g.-964A>G (human)
RGD PMID:17318299 PMID:17878337 PMID:19542437 PMID:20817868 PMID:26595888 RGD:11076728 RGD:4145651 RGD:5128479 RGD:5128485 RGD:5128491 NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635
JBrowse link
G IL27RA interleukin 27 receptor subunit alpha ISO RGD PMID:16081811 RGD:5128496 NCBI chr20:48,456,766...48,475,414
Ensembl chr20:48,457,134...48,472,450
JBrowse link
G IL29L interleukin 29-like exacerbates ISO associated with common cold;protein:increased expression: nasal cavity (human)
associated with common cold;mRNA:decreased expression:sputum (human)
RGD PMID:22135341 PMID:25784275 RGD:126848770 RGD:126848775 NCBI chr24:36,440,445...36,441,017
Ensembl chr24:36,440,445...36,441,017
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:17351063 PMID:20525707 PMID:21377197 RGD:2325990 RGD:5147437 RGD:5147445 NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643
JBrowse link
G IL2RB interleukin 2 receptor subunit beta ISO DNA:SNP: :rs2284033 (human) RGD PMID:18641329 PMID:20860503 RGD:5024942 RGD:5147447 NCBI chr10:27,370,797...27,388,775
Ensembl chr10:27,370,797...27,388,775
JBrowse link
G IL3 interleukin 3 susceptibility ISO DNA:polymorphism:cds:+79T>C(S27P)(human)
DNA:SNP: :rs40401(human)
RGD PMID:15372320 PMID:24684517 RGD:13506914 RGD:13506916 NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668
JBrowse link
G IL32 interleukin 32 ISO protein:increased expression:blood serum (human) RGD PMID:22336080 RGD:150340749 NCBI chr 6:38,119,287...38,122,979 JBrowse link
G IL33 interleukin 33 treatment
severity
ISO CTD Direct Evidence: marker/mechanism
associated with viral pneumonia;
associated with fungal infectious disease
CTD
RGD
PMID:19198610 PMID:21804549 PMID:24241537 PMID:25746970 PMID:27472835 More... RGD:39938968 RGD:39939002 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721
JBrowse link
G IL4 interleukin 4 treatment
no_association
ISO mRNA, protein:increase expression:leukocyte, serum
protein:increased expression:respiratory system fluid/secretion
DNA:polymorphism (human)
DNA:SNP: :589C>T (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
mRNA:increased expression:lung, spleen
RGD
CTD
PMID:18211752 PMID:18357729 PMID:20524005 PMID:21103062 PMID:21354484 More... RGD:10402791 RGD:10402799 RGD:2317290 RGD:4889866 RGD:5128500 RGD:5128502 RGD:5128557 RGD:5128560 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL4R interleukin 4 receptor disease_progression
susceptibility
severity
ISO DNA:SNPs:cds:p.E375A, Q551R (human)
DNA:polymorphism::-1902G/A (human)
DNA:SNPs: :multiple
DNA:mutation:cds:p.Q576R (mouse)
DNA:polymorphism:cds:p.Q551R (human)
protein:increased secretion:plasma
DNA:SNPs:cds:p. I75V, Q576R (human)
DNA:polymorphism:cds:p.I50V (human)
DNA:polymorphism:cds:p.Q576R (human)
DNA:polymorphism:cds:p. S478P (human)
RGD PMID:11398072 PMID:11709756 PMID:12133990 PMID:12940513 PMID:15479272 More... RGD:4890003 RGD:4890024 RGD:4890346 RGD:4890347 RGD:4890348 RGD:4890349 RGD:4890351 RGD:4890352 RGD:4890387 RGD:4890402 RGD:4890404 RGD:4890406 RGD:5128514 RGD:5128553 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G IL5 interleukin 5 treatment
disease_progression
ISO DNA:polymorphism:promoter:-703C>T (human)
protein: increased levels: sputum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lungs, respiratory system fluid/secretion
protein:increased expression:respiratory system fluid/secretion
RGD
CTD
PMID:7540862 PMID:9182686 PMID:9493449 PMID:11159041 PMID:15502111 More... RGD:11354973 RGD:4145461 RGD:4890938 RGD:4890940 RGD:4890947 RGD:4890948 RGD:4890962 RGD:4890963 RGD:5687140 RGD:5687144 RGD:5687189 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G IL5RA interleukin 5 receptor subunit alpha ISO DNA:SNP: :c.25091G>A (human)
DNA:SNPs (human)
RGD PMID:10224351 PMID:10848907 PMID:16217591 PMID:17276963 PMID:20513521 More... RGD:5128614 RGD:5128617 RGD:5128623 RGD:5128625 RGD:5128626 RGD:5128627 NCBI chr20:14,309,805...14,349,433
Ensembl chr20:14,314,227...14,343,793
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
associated with Hypersensitivity;protein:increased expression:sputum
CTD
RGD
PMID:20658762 PMID:20816188 PMID:20840469 PMID:21115736 PMID:29902480 RGD:4143265 RGD:4143266 RGD:4143271 RGD:5128630 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G IL6R interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17496315 PMID:21115736 PMID:29902480 RGD:5128630 RGD:5128662 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090
JBrowse link
G IL9 interleukin 9 ISO protein:increased expression:sputum, macrophage, cytoplasm
protein:increased expression:respiratory system fluid/secretion
RGD PMID:12153980 PMID:15303135 PMID:15531759 PMID:17446528 PMID:21356110 RGD:5128686 RGD:5128690 RGD:5128691 RGD:5128700 RGD:5128707 NCBI chr11:23,808,919...23,814,085
Ensembl chr11:23,811,117...23,814,079
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 5 OMIM
ClinVar
PMID:17503328 NCBI chr10:8,683,541...8,730,757
Ensembl chr10:8,684,242...8,729,268
JBrowse link
G IRF1 interferon regulatory factor 1 susceptibility
no_association
ISO protein:increased expression:respiratory tract epithelium
DNA:repeat:intron (human)
DNA:polymorphisms:promoter, cds:-300G>T, 4396A>G, 6355G>A (human)
RGD PMID:10225979 PMID:11069564 PMID:16961714 RGD:5128723 RGD:5128724 RGD:5128726 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608
JBrowse link
G IRF3 interferon regulatory factor 3 ISO RGD PMID:20673978 RGD:5128793 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065
JBrowse link
G ITGB3 integrin subunit beta 3 ISO DNA:SNPs: : RGD PMID:17556058 RGD:5037230 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 ISO RGD PMID:21777465 RGD:5147661 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198
JBrowse link
G KDR kinase insert domain receptor ISO associated with Rhinitis,Allergic,Seasonal;protein:increased expression:nasal cavity of mucosa: RGD PMID:17651148 PMID:20921519 RGD:5684385 RGD:8551771 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042
JBrowse link
G KIF3A kinesin family member 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr11:20,988,516...21,044,151
Ensembl chr11:20,928,655...21,044,090
JBrowse link
G KRT19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15478392 NCBI chr 9:21,240,778...21,245,039 JBrowse link
G LEP leptin ISO protein:increased expression:plasma RGD PMID:19705789 RGD:5128781 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395
JBrowse link
G LGALS3 galectin 3 treatment ISO RGD PMID:16424226 RGD:9685213 NCBI chr 8:30,977,438...30,994,711
Ensembl chr 8:30,983,633...30,994,705
JBrowse link
G LOC102156778 bone marrow proteoglycan-like severity
disease_progression
no_association
ISO mRNA:increased expression:eosinophil:
associated with viral infection;mRNA:increased expression:sputum:
associated with cough;protein:increased expression:sputum:
RGD PMID:11067904 PMID:16982448 PMID:22022864 PMID:24450586 RGD:13506941 RGD:13506942 RGD:13506943 RGD:13506944 NCBI chr18:38,753,269...38,760,730 JBrowse link
G LOC106557449 alveolar macrophage chemotactic factor-like ISO mRNA:increased expression:bronchus epithelium RGD PMID:17234659 RGD:5135243 NCBI chr13:62,514,244...62,516,439
Ensembl chr13:62,513,898...62,515,218
JBrowse link
G LOC478984 low affinity immunoglobulin gamma Fc region receptor III susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human) RGD PMID:18199088 RGD:5508449 NCBI chr38:21,054,870...21,060,948 JBrowse link
G LOC479911 glutathione S-transferase Mu 3 ISO DNA:polymorphism RGD PMID:11470996 PMID:17550934 RGD:5135038 RGD:5135039 NCBI chr 6:42,187,869...42,191,274
Ensembl chr 6:42,187,967...42,191,273
JBrowse link
G LOC610540 pulmonary surfactant-associated protein A-like ISO protein:decreased expression:lung
mRNA, protein:increased expression:lung
protein:decreased expression:lung, Clara cell, pneumocyte
RGD PMID:15816355 PMID:16629790 PMID:18802356 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143516 NCBI chr 4:29,430,139...29,434,640 JBrowse link
G LOC611642 interleukin-9 receptor ISO RGD PMID:10629460 RGD:5128704 NCBI chr 6:40,425,072...40,437,917 JBrowse link
G LTA lymphotoxin alpha susceptibility
no_association
ISO DNA:polymorphism:intron
DNA:polymorphisms:promoter
RGD PMID:12530118 PMID:15969671 PMID:17536219 PMID:18947013 RGD:4143254 RGD:4143370 RGD:4143371 RGD:4143373 NCBI chr12:1,070,608...1,073,053
Ensembl chr12:1,071,192...1,073,067
JBrowse link
G LTA4H leukotriene A4 hydrolase ISO mRNA:increased expression:lung, cerebral cortex (rat) RGD PMID:15715933 RGD:2316607 NCBI chr15:35,795,934...35,830,681
Ensembl chr15:35,795,979...35,830,844
JBrowse link
G MBL1 mannose binding lectin 1 susceptibility ISO DNA:SNP:cds:p.G54D(human)
associated with Bronchiolitis;DNA:polymorphism:exon:
RGD PMID:22512728 PMID:22674410 RGD:12910828 RGD:8693709 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G MEFV MEFV innate immuity regulator, pyrin susceptibility ISO DNA:mutations:exons RGD PMID:18219832 RGD:5129186 NCBI chr 6:37,964,776...37,984,830
Ensembl chr 6:37,970,608...37,983,737
JBrowse link
G MIF macrophage migration inhibitory factor severity ISO protein:increased expression:bronchoalveolar lavage fluid
DNA:repeats:promoter
DNA:SNP:promoter:rs755622(human)
RGD PMID:9637721 PMID:16186482 PMID:16455830 PMID:17373669 PMID:19317738 RGD:1641985 RGD:4891035 RGD:4891043 RGD:4891052 RGD:4891059
G MMP1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24469321 NCBI chr 5:28,978,385...28,986,644
Ensembl chr 5:28,978,473...28,986,648
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO DNA:SNP: : rs2664538(human)
protein:increased expression:lung
protein:increased expression:serum
mRNA, protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11742282 PMID:15131573 PMID:16191269 PMID:19361849 PMID:19940022 More... RGD:2325953 RGD:5129204 RGD:5129522 RGD:5129687 RGD:5130859 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293
JBrowse link
G MPO myeloperoxidase susceptibility ISO protein:increased expression:serum
DNA:polymorphism: :−463G > A (human)
RGD PMID:10731862 PMID:19544176 RGD:5130989 RGD:5130994 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility ISO DNA:SNP: : -109C>T (human)
Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G
DNA:SNPs:multiple:, rs573790, rs2583476, rs569108
DNA:SNPs: : rs556917, rs502581, rs502419 (human)
RGD PMID:8817330 PMID:19218813 PMID:19862939 PMID:21320344 RGD:1599903 RGD:5131092 RGD:5131149 RGD:5131151 NCBI chr21:50,439,133...50,456,785
Ensembl chr21:50,450,024...50,456,785
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:20456312 RGD:4891145 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818
JBrowse link
G MUC1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:11802251 RGD:5131281 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO associated with hypersensitivity RGD PMID:11062147 PMID:14594655 RGD:5131178 RGD:7349354 NCBI chr18:45,416,347...45,438,226 JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming treatment ISO mRNA,protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD PMID:14594655 PMID:17590487 PMID:17698377 PMID:21549818 PMID:21780541 RGD:2324962 RGD:5131204 RGD:7349354 RGD:7349407 RGD:7364729 NCBI chr18:45,471,232...45,498,961 JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming ISO protein:altered expression:sputum RGD PMID:11587997 PMID:11802783 RGD:5131252 RGD:7364763 NCBI chr18:45,517,479...45,545,765
Ensembl chr18:45,517,474...45,545,184
JBrowse link
G MUC7 mucin 7, secreted susceptibility ISO ClinVar Annotator: match by term: Asthma, protection against OMIM
ClinVar
PMID:11378823 PMID:16759176 NCBI chr13:59,805,768...59,813,415 JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 1:27,908,309...27,991,984
Ensembl chr 1:27,908,364...27,991,969
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ameliorates ISO RGD PMID:26882889 RGD:11531666 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534
JBrowse link
G MYLK myosin light chain kinase ISO RGD PMID:17472811 RGD:4891492 NCBI chr33:26,663,991...26,867,370
Ensembl chr33:26,664,800...26,843,181
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 severity ISO mRNA:increased expression:bronchoalveolar lavage cell, peripheral blood mononuclear cell (human) RGD PMID:21514635 RGD:6893376 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
G NGF nerve growth factor severity ISO protein:increased expression:lung, serum
protein:increased expression:blood, eosinophil
RGD PMID:11737043 PMID:12752594 PMID:17164945 PMID:17497413 RGD:4891068 RGD:4891108 RGD:4891122 RGD:4891123 NCBI chr17:52,900,647...52,901,607
Ensembl chr17:52,900,647...52,901,607
JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:12540484 PMID:16603479 RGD:5144070 RGD:5144072 NCBI chr 9:25,598,468...25,621,021
Ensembl chr 9:25,601,074...25,623,274
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 susceptibility ISO DNA:SNP: :rs2075817 (human)
DNA:insertion:cds:
RGD PMID:15718249 PMID:16918516 RGD:5131518 RGD:5131519 NCBI chr14:43,162,671...43,226,948
Ensembl chr14:43,163,571...43,227,103
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility ISO DNA:polymorphisms:intron, exon/3'UTR (rs1077861, rs3135500) (human) RGD PMID:16008671 PMID:21051079 RGD:5131477 RGD:5508757 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232
JBrowse link
G NOS1 nitric oxide synthase 1 susceptibility ISO DNA:repeats:intron
DNA:repeats:exon
DNA:repeats: :
RGD PMID:10673365 PMID:10833424 PMID:14767694 PMID:20609134 RGD:5132615 RGD:5132860 RGD:5132863 RGD:5132869 NCBI chr26:13,787,341...13,895,176
Ensembl chr26:13,786,309...13,962,332
JBrowse link
G NOS2 nitric oxide synthase 2 severity
no_association
disease_progression
ISO mRNA:increased expression:monocyte
CTD Direct Evidence: marker/mechanism
DNA:repeats:promoter, introns (human)
protein:increased expression, increased activity:lung (rat)
associated with Rhinitis, Allergic, Seasonal; protein:increased expression:nasal mucosa
DNA:repeat:promoter
DNA:SNP:exon:p.S608L (human)
protein:increased expression:lung, bronchoalveolar lavage fluid
RGD
CTD
PMID:16540403 PMID:16703578 PMID:17161822 PMID:17177683 PMID:17189532 More... RGD:4891419 RGD:4891480 RGD:4891508 RGD:4891910 RGD:4891924 RGD:4891925 RGD:4891927 RGD:4891953 RGD:4891957 RGD:5509073 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility ISO DNA:snps, repeat, haplotype:promoter, introns, exons:multiple (human)
DNA:repeats:intron
DNA:polymorphisms:promoter:c. -786C>T, -691C>T (human)
RGD PMID:16081038 PMID:16837812 PMID:18486767 RGD:4892053 RGD:4892058 RGD:4892062 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G NPSR1 neuropeptide S receptor 1 susceptibility ISO ClinVar Annotator: match by term: Asthma-related traits, susceptibility to, 2 OMIM
ClinVar
PMID:15073379 NCBI chr14:46,465,169...46,610,256
Ensembl chr14:46,466,544...46,609,477
JBrowse link
G NPY neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:9731035 NCBI chr14:37,824,579...37,831,289
Ensembl chr14:37,823,861...37,831,443
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:c.609C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:c. 609C>T (human)
RGD
CTD
PMID:19027876 PMID:19591959 PMID:20049212 RGD:5135005 RGD:5135006 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment
severity
susceptibility
ISO protein:increased expression, decreased activity:leukocyte, mononuclear
DNA:polymorphism:intron
RGD PMID:15295049 PMID:18396779 PMID:18799869 PMID:20727335 PMID:21113676 RGD:4892328 RGD:4892568 RGD:4892594 RGD:4892609 RGD:7174728 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755
JBrowse link
G NTF3 neurotrophin 3 ISO protein:increased expression:lung, serum RGD PMID:11737043 PMID:17497413 RGD:4891068 RGD:4891123 NCBI chr27:39,383,017...39,454,613
Ensembl chr27:39,383,152...39,454,601
JBrowse link
G NTF4 neurotrophin 4 ISO protein:increased expression:lung, serum RGD PMID:17497413 RGD:4891068 NCBI chr 1:107,371,335...107,377,238
Ensembl chr 1:107,371,335...107,376,987
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA:increased expression:lung: RGD PMID:16708804 PMID:20934630 RGD:5684766 RGD:5684772 NCBI chr 7:41,140,931...41,159,326
Ensembl chr 7:41,140,879...41,159,288
JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21150878 PMID:25256354 NCBI chr 9:22,594,425...22,601,108
Ensembl chr 9:22,594,480...22,599,999
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO RGD PMID:19822647 PMID:22010907 RGD:6480532 RGD:6480533 NCBI chr23:45,908,574...45,954,675
Ensembl chr23:45,909,485...45,910,526
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 treatment ISO protein:increased activation:lung, blood, mononuclear cell
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12594058 PMID:18261157 PMID:26205779 RGD:11073727 RGD:5683910 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127
JBrowse link
G PDCD1 programmed cell death 1 treatment ISO associated with Chlamydia pneumonia RGD PMID:26378990 RGD:41412180 NCBI chr25:51,606,559...51,618,903
Ensembl chr25:51,608,173...51,618,723
JBrowse link
G PDE4B phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21912604 NCBI chr 5:44,063,145...44,606,070
Ensembl chr 5:44,065,106...44,500,999
JBrowse link
G PDE4D phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:19426955 PMID:21611147 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein: increased expression RGD PMID:21216974 RGD:6483071 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746
JBrowse link
G PGF placental growth factor ISO RGD PMID:22268141 RGD:6483605 NCBI chr 8:48,059,554...48,110,534
Ensembl chr 8:48,059,552...48,075,170
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:18754810 RGD:6482695 NCBI chr18:13,576,966...13,611,748
Ensembl chr18:13,570,999...13,611,141
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:18188456 RGD:8693422 NCBI chr20:51,156,887...51,168,131
Ensembl chr20:51,157,121...51,168,136
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:15557087 RGD:1642462 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936
JBrowse link
G PLA2G7 phospholipase A2 group VII susceptibility ISO ClinVar Annotator: match by term: Asthma and atopy, susceptibility to OMIM
ClinVar
PMID:10733466 PMID:15115767 NCBI chr12:14,866,229...14,908,230
Ensembl chr12:14,866,229...14,908,114
JBrowse link
G PLAU plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18519237 PMID:21912604 RGD:4892037 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22205926 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052
JBrowse link
G PRF1 perforin 1 ISO RGD PMID:21426642 PMID:22250087 RGD:6482815 RGD:6482818 NCBI chr 4:21,497,865...21,502,429
Ensembl chr 4:21,498,249...21,500,864
JBrowse link
G PRMT1 protein arginine methyltransferase 1 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075
JBrowse link
G PRMT2 protein arginine methyltransferase 2 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr31:39,806,086...39,838,959
Ensembl chr31:39,807,593...39,838,972
JBrowse link
G PRMT3 protein arginine methyltransferase 3 ISO mRNA:increased expression:lung RGD PMID:20423833 RGD:9491823 NCBI chr21:42,406,327...42,530,157
Ensembl chr21:42,406,314...42,528,116
JBrowse link
G PRMT5 protein arginine methyltransferase 5 ISO mRNA:increased expression:lung, spleen RGD PMID:20423833 RGD:9491823 NCBI chr 8:3,248,349...3,257,567
Ensembl chr 8:3,248,404...3,257,456
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:26381519 RGD:11099992 NCBI chr19:23,173,626...23,183,634
Ensembl chr19:23,173,635...23,183,563
JBrowse link
G PTEN phosphatase and tensin homolog ISO CTD Direct Evidence: therapeutic CTD PMID:17982072 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176
JBrowse link
G PTGDR prostaglandin D2 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 8:28,480,446...28,491,331
Ensembl chr 8:28,480,478...28,488,855
JBrowse link
G PTGDR2 prostaglandin D2 receptor 2 ISO Aspirin exacerbated asthma
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:18757520 PMID:19392992 PMID:19796209 PMID:27103662 RGD:5135018 RGD:5135019 RGD:5135020 NCBI chr18:55,426,632...55,431,916
Ensembl chr18:55,429,308...55,430,510
JBrowse link
G PTGER3 prostaglandin E receptor 3 treatment ISO RGD PMID:23221044 RGD:10043366 NCBI chr 6:74,932,789...74,986,573 JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility
severity
ISO DNA:SNP: :8473T>C (human)
mRNA:increased expression:lung
mRNA, protein:increased expression:lung:
DNA:SNP: :rs689465 (human)
RGD PMID:15316498 PMID:17573729 PMID:18097056 PMID:18489027 PMID:19342146 More... RGD:5135514 RGD:5135515 RGD:5135522 RGD:5135526 RGD:5135534 RGD:5143923 RGD:5143931 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G RAD50 RAD50 double strand break repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24241537 NCBI chr11:20,836,863...20,928,930
Ensembl chr11:20,836,879...20,928,819
JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:18391481 RGD:2298885 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 susceptibility ISO associated with allergic rhinitis; DNA:SNP:exon:38G>A (human)
ClinVar Annotator: match by term: Asthma, susceptibility to
RGD
ClinVar
PMID:9550363 PMID:9643286 PMID:12100044 PMID:21255142 RGD:5144226 NCBI chr18:54,187,487...54,191,493
Ensembl chr18:54,187,487...54,191,482
JBrowse link
G SCGB3A2 secretoglobin family 3A member 2 susceptibility
severity
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:SNP:promoter:-112G>A (human)
OMIM
ClinVar
RGD
PMID:11813133 PMID:18089940 PMID:18201431 RGD:5144230 RGD:5144231 NCBI chr 2:42,147,596...42,151,224
Ensembl chr 2:42,147,596...42,151,191
JBrowse link
G SELL selectin L ISO RGD PMID:21437035 PMID:21515793 RGD:5685685 RGD:5685696 NCBI chr 7:28,906,752...28,927,959
Ensembl chr 7:28,906,809...29,094,008
JBrowse link
G SERPINA1 serpin family A member 1 ISO Fisher rats, shown to exhibit hyperactive airway responses at 14 days of age, had higher transcript and protein levels of Serpina1 than same age Brown Norway rats. RGD PMID:20118217 RGD:5131869 NCBI chr 8:63,388,498...63,400,377
Ensembl chr 8:63,376,945...63,398,435
JBrowse link
G SERPINE1 serpin family E member 1 severity
no_association
susceptibility
ISO protein:increased activity, increased expression:plasma, lung
protein:increased expression:plasma
DNA:polymorphism:promoter:rs1799768 (human)
RGD PMID:18594148 PMID:19063817 PMID:19604112 PMID:19703828 RGD:4144831 RGD:4144832 RGD:4144833 RGD:4144836 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301
JBrowse link
G SFTPB surfactant protein B ISO protein:increased expression:lung
protein:decreased expression:lung, Clara cell
mRNA, protein:decreased expression:lung
RGD PMID:11472974 PMID:15816355 PMID:16629790 PMID:18926058 RGD:4143289 RGD:4143398 RGD:4143462 RGD:4143465 NCBI chr17:39,419,305...39,428,513
Ensembl chr17:39,386,584...39,426,229
JBrowse link
G SFTPC surfactant protein C susceptibility ISO mRNA, protein:decreased expression:lung
protein:increased expression:lung
DNA:polymorphism: :p.A53T (human)
RGD PMID:11472974 PMID:16629790 PMID:19910179 RGD:4143462 RGD:4143465 RGD:4144063 NCBI chr25:35,088,295...35,090,995
Ensembl chr25:35,088,279...35,091,457
JBrowse link
G SFTPD surfactant protein D ISO mRNA, protein:increased expression:lung
associated with Bronchitis;protein:increased expression:lung
RGD PMID:11472974 PMID:16629790 PMID:16839409 PMID:18266831 PMID:18802356 RGD:4143462 RGD:4143465 RGD:4143508 RGD:4143516 RGD:4143517 NCBI chr 4:29,394,755...29,407,499
Ensembl chr 4:29,394,678...29,407,293
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:12847242 RGD:5684966 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO RGD PMID:17328924 RGD:5686690 NCBI chr28:1,476,873...1,478,538
Ensembl chr28:1,476,774...1,478,505
JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO RGD PMID:17328924 RGD:5686690 NCBI chr 1:49,268,978...49,296,522 JBrowse link
G SLC5A7 solute carrier family 5 member 7 ISO mRNA:decreased expression:lung RGD PMID:17328924 RGD:5686690 NCBI chr10:35,879,880...35,908,203
Ensembl chr10:35,883,245...35,908,569
JBrowse link
G SLC6A4 solute carrier family 6 member 4 susceptibility ISO DNA:repeat:intron (human) RGD PMID:19806585 RGD:4889460 NCBI chr 9:44,224,026...44,259,655
Ensembl chr 9:44,224,229...44,259,736
JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22867017 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:15743779 RGD:1581231 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G STAT4 signal transducer and activator of transcription 4 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18211752 PMID:28807506 RGD:2317290 NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894
JBrowse link
G STAT6 signal transducer and activator of transcription 6 treatment ISO RGD PMID:16083555 PMID:19087723 RGD:7244151 RGD:7244153 NCBI chr10:1,232,515...1,247,011
Ensembl chr10:1,233,691...1,247,075
JBrowse link
G TAC1 tachykinin precursor 1 ISO protein:increased expression:lung RGD PMID:11031342 RGD:5147836 NCBI chr14:22,631,106...22,640,283
Ensembl chr14:22,632,642...22,640,258
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA,protein:increased expression:lung
mRNA:increased expression:lung
RGD PMID:8240667 PMID:16409782 PMID:17392578 RGD:2304339 RGD:5147475 RGD:5147645 NCBI chr17:48,038,010...48,178,971
Ensembl chr17:48,038,010...48,178,971
JBrowse link
G TACR2 tachykinin receptor 2 ISO DNA:SNP:cds:p.G231E (human) RGD PMID:19880429 PMID:20175803 RGD:5147640 RGD:5147641 NCBI chr 4:20,518,797...20,531,118
Ensembl chr 4:20,517,563...20,531,867
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphism: : RGD PMID:12640628 RGD:5147845 NCBI chr12:2,424,049...2,432,165
Ensembl chr12:2,378,126...2,432,303
JBrowse link
G TBX21 T-box transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15806396 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261
JBrowse link
G TBXA2R thromboxane A2 receptor severity
susceptibility
ISO DNA:polymorphism:cds:924T>C(human) RGD PMID:12000493 PMID:15805995 RGD:11059534 RGD:11059535 NCBI chr20:55,819,866...55,829,395
Ensembl chr20:55,824,410...55,828,980
JBrowse link
G THBD thrombomodulin ISO RGD PMID:20709825 RGD:5684984 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16926187 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288
JBrowse link
G TLR1 toll like receptor 1 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 3:73,504,359...73,544,822
Ensembl chr 3:73,539,715...73,544,624
JBrowse link
G TLR10 toll like receptor 10 susceptibility ISO DNA:SNP (human) RGD PMID:18547625 RGD:4889528 NCBI chr 3:73,561,596...73,589,286
Ensembl chr 3:73,568,321...73,570,744
JBrowse link
G TLR2 toll like receptor 2 susceptibility
severity
ISO DNA:SNP: :rs4696480 (human)
DNA:SNP: :rs7656411 (human)
DNA:SNP: :rs3804100 (human)
DNA:polymorphism:cds:p.R753Q(human)
DNA:SNP: :596T>C (human)
RGD PMID:18202345 PMID:18787777 PMID:19096003 PMID:19148143 PMID:20685742 More... RGD:2312679 RGD:4144171 RGD:4144228 RGD:4145334 RGD:4145343 RGD:4145352 RGD:7800732 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR3 toll like receptor 3 no_association ISO Asthma, Virus-Induced; mRNA:increased expression:sputum (human)
DNA:snp:cds:p.L412F (human)
RGD PMID:14987294 PMID:17434873 PMID:17610940 PMID:21129050 PMID:21364926 RGD:5128500 RGD:5129226 RGD:5129475 RGD:5129478 RGD:5129493 NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247
JBrowse link
G TLR4 toll like receptor 4 susceptibility
severity
no_association
ISO DNA:Polymorphism:cds:p.D299G (human)
DNA:polymorphisms:cds:c.896A>G, 1196C>T (human)
DNA:SNPs: :rs10983755, rs1927914 (human)
protein:decreased expression:leukocytes, mononuclear
DNA:SNPs::
RGD PMID:15356557 PMID:16266379 PMID:19067129 PMID:19159017 PMID:19330007 More... RGD:4144141 RGD:4144171 RGD:4144176 RGD:4144188 RGD:4144190 RGD:4144198 RGD:4144817 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TLR6 toll like receptor 6 susceptibility ISO DNA:SNP (human)
DNA:SNP: :p.S249P (human)
RGD PMID:15266299 PMID:18547625 RGD:4889528 RGD:4889538 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099
JBrowse link
G TLR9 toll like receptor 9 susceptibility
severity
no_association
ISO DNA:SNP:promoter:g.-1237T>C (rs5743836) (human)
protein:increased expression:peripheral blood mononuclear cell (human)
DNA:SNP:promoter:g.-1237T>C rs5743836 (human)
RGD PMID:18312481 PMID:20016192 PMID:20072849 PMID:21324137 RGD:4144208 RGD:4889523 RGD:5129104 RGD:5130712 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114
JBrowse link
G TNC tenascin C ISO protein:increased expression:bronchus basement membrane
DNA:SNP:exon:p.L1677I (human)
DNA:SNPs: :multiple (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9310019 PMID:16115819 PMID:17125141 PMID:18305139 RGD:4889565 RGD:4889569 RGD:4889572 RGD:4889589 NCBI chr11:69,077,532...69,169,673
Ensembl chr11:69,077,535...69,170,281
JBrowse link
G TNF tumor necrosis factor susceptibility
no_association
ISO ClinVar Annotator: match by term: Asthma, susceptibility to
DNA:polymorphism:promoter:
OMIM
ClinVar
RGD
PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:4143254 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:lung (mouse) RGD PMID:20484920 RGD:5131201 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282
JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24453940 NCBI chr 4:58,150,734...58,200,158
Ensembl chr 4:58,149,882...58,199,644
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 severity ISO CTD Direct Evidence: marker/mechanism
ovalbumin sensitization
CTD
RGD
PMID:19458046 PMID:31969645 RGD:127285811 NCBI chr29:20,951,736...21,000,956
Ensembl chr29:20,951,716...21,001,208
JBrowse link
G TSLP thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21804549 NCBI chr 3:1,502,469...1,507,696
Ensembl chr 3:1,503,188...1,507,696
JBrowse link
G UCN urocortin ISO associated with Hypersensitivity;mRNA, protein:increased expression:lung RGD PMID:16427607 RGD:1642781 NCBI chr17:21,278,512...21,280,404
Ensembl chr17:21,278,932...21,279,312
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:17045018 RGD:2306832 NCBI chr 5:61,503,268...61,508,146 JBrowse link
G VDR vitamin D receptor no_association ISO DNA:SNP (human)
DNA:SNPs (human)
DNA:SNP: :rs7975232 (human)
DNA:SNPs: :multiple (human)
RGD PMID:15282200 PMID:19622139 PMID:20124605 PMID:21103062 RGD:4889854 RGD:4889866 RGD:4889867 RGD:4889868 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:sputum
CTD
RGD
PMID:11907124 PMID:15201500 PMID:19178538 PMID:19263519 RGD:6892723 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:16782752 PMID:21419198 RGD:5685381 RGD:5685620 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700
JBrowse link
G WDR36 WD repeat domain 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr 3:1,451,543...1,494,474
Ensembl chr 3:1,451,555...1,494,438
JBrowse link
Asthma and Nasal Polyps term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLA-DRA MHC class II DR alpha chain susceptibility ISO DNA:SNPs,haplotype:introns: RGD PMID:22391069 RGD:13506908 NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975
JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma and nasal polyps ClinVar PMID:15806396 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261
JBrowse link
asthma, nasal polyps, and aspirin intolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance ClinVar PMID:17959182 PMID:21558275 PMID:30643255 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119
JBrowse link
G PTGER2 prostaglandin E receptor 2 ISO OMIM NCBI chr 8:28,523,318...28,536,936
Ensembl chr 8:28,522,681...28,536,922
JBrowse link
G TBX21 T-box transcription factor 21 ISO ClinVar Annotator: match by term: Asthma, nasal polyps, and aspirin intolerance OMIM
ClinVar
PMID:25741868 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261
JBrowse link
atopic dermatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTL9 actin like 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr20:53,176,345...53,179,880
Ensembl chr20:53,178,504...53,179,754
JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444
JBrowse link
G APOE apolipoprotein E ISO protein:decreased expression:plasma RGD PMID:19116453 RGD:11040546 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G ARTN artemin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817
G B9D2 B9 domain containing 2 ISO RGD PMID:11496247 RGD:7394812 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BDNF brain derived neurotrophic factor no_association
susceptibility
ISO protein:increased expression:serum:
DNA:polymorphism:cds:p.V66M(human)
mRNA:decreased expression:mast cell
DNA:polymorphism::C270T(human)
RGD PMID:17073871 PMID:17845420 PMID:19038326 PMID:19522715 RGD:8657028 RGD:8657065 RGD:8657067 RGD:8657069 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480
JBrowse link
G C3 complement C3 ISO protein:increased expression:plasma RGD PMID:3923750 RGD:7401273 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761
JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 PMID:28628108 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094
JBrowse link
G CCDC80 coiled-coil domain containing 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr33:17,105,086...17,141,380
Ensembl chr33:17,105,086...17,139,896
JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 2:59,001,463...59,014,347
Ensembl chr 2:59,001,464...59,005,230
JBrowse link
G CCL20 C-C motif chemokine ligand 20 severity
treatment
ISO protein:increased expression:plasma RGD PMID:11133838 PMID:19162238 RGD:7483580 RGD:7483583 NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 PMID:22125604 NCBI chr 2:59,039,650...59,045,519
Ensembl chr 2:59,040,539...59,045,625
JBrowse link
G CCL24 C-C motif chemokine ligand 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 6:7,166,165...7,179,606
Ensembl chr 6:7,166,479...7,180,051
JBrowse link
G CCL26 C-C motif chemokine ligand 26 ISO protein:increased expression:serum (human) RGD PMID:14616792 RGD:11087554 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726
JBrowse link
G CCL27 C-C motif chemokine ligand 27 ISO RGD PMID:12642842 RGD:1626250 NCBI chr11:51,334,870...51,338,752
Ensembl chr11:51,334,778...51,335,591
JBrowse link
G CCL28 C-C motif chemokine ligand 28 severity ISO associated with Asthma; protein: increased secretion:serum (human) RGD PMID:20161852 RGD:4892193 NCBI chr 4:66,567,139...66,597,310
Ensembl chr 4:66,566,989...66,597,459
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO protein:increased expression:skin,monocyte: RGD PMID:15370700 RGD:8661734 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO protein:increased expression:skin
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16449815 PMID:18249437 RGD:6893391 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:16449815 PMID:18249437 RGD:6893391 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952
JBrowse link
G CD40 CD40 molecule ISO RGD PMID:18693155 RGD:5132274 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301
JBrowse link
G CDSN corneodesmosin ISO protein:decreased expression:skin of body (human) RGD PMID:21211653 RGD:42721970 NCBI chr12:819,488...824,015
Ensembl chr12:820,467...823,986
JBrowse link
G CLDN1 claudin 1 ISO DNA:SNPs:intron,promoter :rs17501010,rs9290927,rs893051,rs9290929,rs16865373(human) RGD PMID:21163515 RGD:11344875 NCBI chr34:22,303,058...22,319,101
Ensembl chr34:22,303,850...22,319,033
JBrowse link
G CLDN23 claudin 23 ISO mRNA:decreased expression:epidermis: RGD PMID:21163515 RGD:11344875 NCBI chr16:35,786,709...35,788,430 JBrowse link
G CMA1 chymase 1 ISO DNA:polymorphism:5' utr:g.-1903G>A rs1800875 (human) RGD PMID:16134991 RGD:1625394 NCBI chr 8:4,438,244...4,441,189
Ensembl chr 8:4,438,244...4,441,189
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility ISO mRNA:increased expression:blood:
DNA:SNP,haplotype:exon,3'UTR:rs3087243,rs231775 (human)
RGD PMID:16445777 PMID:22357516 RGD:7411698 RGD:7411700 NCBI chr37:12,647,712...12,653,874
Ensembl chr37:12,634,563...12,653,874
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO protein:increased expression:serum RGD PMID:15131578 RGD:9491761 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO protein:decreased expression:blood, leukocyte RGD PMID:15131578 PMID:24821910 RGD:9491393 RGD:9491761 NCBI chr23:8,937,069...8,954,738
Ensembl chr23:8,938,906...8,952,808
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr  X:55,882,433...55,884,582
Ensembl chr  X:55,882,433...55,884,582
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869817 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866
JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 ISO ClinVar Annotator: match by term: Atopic eczema ClinVar PMID:25741868 NCBI chr20:46,674,580...46,743,183
Ensembl chr20:46,458,620...46,705,789
JBrowse link
G DOCK8 dedicator of cytokinesis 8 ISO DNA:mutations:cds: RGD PMID:22476911 RGD:40903056 NCBI chr 1:89,152,456...89,379,203
Ensembl chr 1:89,150,856...89,378,013
JBrowse link
G EMSY EMSY transcriptional repressor, BRCA2 interacting ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr21:22,149,131...22,289,857
Ensembl chr21:22,149,127...22,289,875
JBrowse link
G F2 coagulation factor II, thrombin ISO protein:increased expression:plasma RGD PMID:21488867 RGD:5147756 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G FLG filaggrin ISO ClinVar Annotator: match by term: Atopic eczema ClinVar PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17417636 More... NCBI chr17:61,217,915...61,233,068 JBrowse link
G GLB1 galactosidase beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr23:3,721,768...3,814,209
Ensembl chr23:3,732,040...3,814,191
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (rs1695) (human) RGD PMID:19842992 PMID:20674822 RGD:5490540 RGD:5490981 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO RGD PMID:16159638 RGD:5128852 NCBI chr 4:53,012,223...53,066,611
Ensembl chr 4:53,046,970...53,128,952
Ensembl chr 4:53,046,970...53,128,952
JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:19025430 RGD:5128889 NCBI chr19:40,656,266...40,702,498
Ensembl chr19:40,655,161...40,702,218
JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:22101570 RGD:8157618 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IFNL3 interferon lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295096
G IL10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18249437 PMID:23843958 RGD:7364805 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL13 interleukin 13 severity
treatment
ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:4257G>A (human)
DNA:SNPs: :rs3091307, rs20541 (human)
DNA, protein:SNP, increased expression:promoter, serum:-1112C>T (human)
RGD
CTD
PMID:10887320 PMID:16672002 PMID:17313488 PMID:18249437 PMID:19006098 More... RGD:5684364 RGD:8549509 RGD:8549529 RGD:8549531 RGD:8549539 RGD:8549583 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 ISO mRNA:increased expression:skin RGD PMID:14527737 RGD:8549525 NCBI chr  X:90,925,497...90,981,855
Ensembl chr  X:90,924,801...90,979,963
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO protein:increased expression:serum RGD PMID:20971924 PMID:21462799 RGD:8549521 RGD:8549556 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798
JBrowse link
G IL17A interleukin 17A treatment
severity
ISO protein:increased expression:epidermis (mouse)
protein:increased expression:dermis, lymphocyte (human)
RGD PMID:18432274 PMID:22848348 PMID:24337738 RGD:8698670 RGD:9068417 RGD:9068436 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL18 interleukin 18 no_association
severity
ISO protein:increased expression:serum
DNA:SNP:promoter:-137G>C (rs187238) (human)
DNA:SNP:promoter:-140C>G (rs360721) (human)
DNA:SNPs, haplotype: :rs795467, rs4937113, rs5744247 (human)
RGD PMID:11490156 PMID:15317323 PMID:17517100 PMID:22840759 RGD:8655872 RGD:8655876 RGD:8655908 RGD:8655914 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL2 interleukin 2 susceptibility ISO DNA:SNP:promoter:rs2069762(human)
associated with food hypersensitivity;
protein:increased expression:CD8+ T cell:
RGD PMID:1673687 PMID:7547077 PMID:16333313 PMID:16672002 PMID:21982597 RGD:8549583 RGD:8662961 RGD:8663444 RGD:8663473 RGD:8693325 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G IL21R interleukin 21 receptor ISO protein:increased expression:skin RGD PMID:19075398 RGD:6892938 NCBI chr 6:19,181,846...19,217,915
Ensembl chr 6:19,182,071...19,217,931
JBrowse link
G IL25 interleukin 25 ISO protein:increased expression:arm skin RGD PMID:23657503 RGD:39128244 NCBI chr 8:3,621,268...3,624,689
Ensembl chr 8:3,618,161...3,624,043
JBrowse link
G IL31 interleukin 31 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr26:7,173,151...7,175,195
Ensembl chr26:7,172,451...7,175,195
JBrowse link
G IL32 interleukin 32 ISO mRNA:splice variant:zone of skin (human) RGD PMID:28301691 RGD:150340720 NCBI chr 6:38,119,287...38,122,979 JBrowse link
G IL33 interleukin 33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721
JBrowse link
G IL4 interleukin 4 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter:-590C>T (human)
RGD
CTD
PMID:8363440 PMID:9643293 PMID:11886533 PMID:12230500 PMID:18249437 RGD:7829786 RGD:7829795 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL4R interleukin 4 receptor susceptibility ISO DNA:mutation:cds:p.Q576R(human) RGD PMID:9392697 RGD:11530001 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G IL5 interleukin 5 ISO CTD Direct Evidence: marker/mechanism
mRNA: increased expression: skin
CTD
RGD
PMID:11886533 PMID:18249437 PMID:22299064 RGD:5687175 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18249437 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO ClinVar Annotator: match by term: Atopic eczema ClinVar NCBI chr21:39,953,461...39,957,615
Ensembl chr21:39,955,551...39,956,723
JBrowse link
G LOC403581 peptidylprolyl isomerase A (cyclophilin A) pseudogene ISO mRNA:increased expression:zone of skin (human) RGD PMID:32496587 RGD:150383342 NCBI chr 7:80,937,433...80,938,175 JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24046278 NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401
JBrowse link
G MBL1 mannose binding lectin 1 susceptibility ISO DNA:polymorphisms:promoter, exon: RGD PMID:20642202 RGD:8693720 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G MC1R melanocortin 1 receptor ISO protein: increased expression: skin RGD PMID:19889022 RGD:5687321 NCBI chr 5:63,694,296...63,695,249 JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO RGD PMID:27776525 RGD:13204759 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293
JBrowse link
G MS4A2 membrane spanning 4-domains A2 susceptibility ISO Atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:polymorphism:CDS:amino acid E237G RGD PMID:8817330 RGD:1599903 NCBI chr21:50,439,133...50,456,785
Ensembl chr21:50,450,024...50,456,785
JBrowse link
G NGF nerve growth factor ISO protein:increased expression:serum: RGD PMID:17073871 RGD:8657069 NCBI chr17:52,900,647...52,901,607
Ensembl chr17:52,900,647...52,901,607
JBrowse link
G NGFR nerve growth factor receptor ISO protein:increased expression:nerve fibers of the papillary dermis RGD PMID:16586073 RGD:5508452 NCBI chr 9:25,598,468...25,621,021
Ensembl chr 9:25,601,074...25,623,274
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO protein:increased expression:eosinophil RGD PMID:17223862 PMID:18647313 RGD:5144116 RGD:5684771 NCBI chr 7:41,140,931...41,159,326
Ensembl chr 7:41,140,879...41,159,288
JBrowse link
G OVOL1 ovo like transcriptional repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23042114 NCBI chr18:51,454,170...51,465,189
Ensembl chr18:51,455,107...51,464,847
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism
potential therapeutic target with or without glucocorticoid therapy
CTD
RGD
PMID:18249437 PMID:21633371 RGD:5509940 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit ISO RGD PMID:10940923 RGD:7777149 NCBI chr 1:110,436,677...110,466,709
Ensembl chr 1:110,436,662...110,466,809
JBrowse link
G S100A8 S100 calcium binding protein A8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18336422 NCBI chr 7:43,540,667...43,541,604
Ensembl chr 7:43,501,989...43,541,604
JBrowse link
G SELE selectin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:12410700 NCBI chr 7:28,888,503...28,898,787
Ensembl chr 7:28,888,197...28,898,786
JBrowse link
G SELP selectin P ISO atopy and bronchial hyperresponsiveness, OMIM:147050 DNA:point_mutation:CDS:amino acid Val640Leu RGD PMID:12929084 RGD:1599904 NCBI chr 7:28,956,428...28,997,266
Ensembl chr 7:28,958,486...28,996,313
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282
JBrowse link
G STAT6 signal transducer and activator of transcription 6 ISO CTD Direct Evidence: therapeutic CTD PMID:15306842 NCBI chr10:1,232,515...1,247,011
Ensembl chr10:1,233,691...1,247,075
JBrowse link
G TLR2 toll like receptor 2 severity ISO DNA:polymorphism:cds:p.R753Q(human)
DNA:polymorphism: :-16934A>T(human)
RGD PMID:17531301 PMID:19627277 PMID:22032785 RGD:8552997 RGD:8552999 RGD:8553048 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241
JBrowse link
G TLR4 toll like receptor 4 ISO mRNA:increased expression:blood cell:
DNA:polymorphism: :896G>A(human)
RGD PMID:19764566 PMID:23821954 RGD:7794689 RGD:7794745 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TNF tumor necrosis factor susceptibility ISO DNA:haplotype:promoter:−308G>A,-238G>A(human) RGD PMID:22533231 RGD:7401246 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 ISO mRNA:altered expression:fibroblast RGD PMID:16650051 RGD:7777183 NCBI chr19:52,607,598...52,623,799
Ensembl chr19:52,607,713...52,623,811
JBrowse link
G TSLP thymic stromal lymphopoietin treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16880407 PMID:22355542 PMID:23688403 PMID:27869817 PMID:29310423 RGD:38549374 NCBI chr 3:1,502,469...1,507,696
Ensembl chr 3:1,503,188...1,507,696
JBrowse link
G VDR vitamin D receptor severity
no_association
ISO DNA:SNPs, haplotype: :rs731236, rs1544410, rs7975232 (human)
DNA:SNP: :rs2228570 (human)
RGD PMID:23034014 RGD:8157625 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470
JBrowse link
G VNN1 vanin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19322213 NCBI chr 1:25,678,039...25,704,579
Ensembl chr 1:25,678,042...25,696,807
JBrowse link
atopic dermatitis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLG filaggrin susceptibility ISO ClinVar Annotator: match by term: Atopic dermatitis 2 | ClinVar Annotator: match by term: Dermatitis, atopic, 2, susceptibility to OMIM
ClinVar
PMID:16444271 PMID:16550169 PMID:16815158 PMID:17030239 PMID:17291859 More... NCBI chr17:61,217,915...61,233,068 JBrowse link
atopic dermatitis 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOCS3 suppressor of cytokine signaling 3 susceptibility ISO OMIM NCBI chr 9:2,859,267...2,859,944 JBrowse link
berylliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:10194187 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G B9D2 B9 domain containing 2 severity ISO DNA:polymorphisms: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15750822 PMID:17785866 RGD:4145294 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BTNL2 butyrophilin like 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs3117099(human)
CTD
RGD
PMID:17927685 RGD:9685029 NCBI chr12:2,085,589...2,106,787
Ensembl chr12:2,086,324...2,107,124
JBrowse link
G CCR5 C-C motif chemokine receptor 5 disease_progression ISO DNA:polymorphisms:5' utr:multiple (human) RGD PMID:20075058 RGD:4892065 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952
JBrowse link
G CD28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12952926 NCBI chr37:12,503,849...12,536,362
Ensembl chr37:12,503,811...12,532,854
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766924 NCBI chr 6:55,204,602...55,244,217 JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16272364 PMID:17927685 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HMOX1 heme oxygenase 1 ISO protein:increased activity:sputum RGD PMID:19453654 RGD:4145349 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8977230 NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 PMID:12449171 PMID:15127972 PMID:16980557 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
bird fancier's lung term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MUC1 mucin 1, cell surface associated ISO protein:increased expression:serum RGD PMID:15881280 RGD:5131172 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690
JBrowse link
childhood-onset asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha exacerbates ISO associated with respiratory syncytial virus infectious disease;DNA:SNPs:protomer: (rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433
JBrowse link
dermatographia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRE2 adhesion G protein-coupled receptor E2 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr20:47,929,357...47,968,525
Ensembl chr20:47,873,897...47,968,525
JBrowse link
egg allergy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO protein:increased expression:brain, cingulate cortex (rat) RGD PMID:19208366 RGD:2326032 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680
JBrowse link
G IL13 interleukin 13 ISO associated with Dermatitis, Atopic; DNA:SNPs:promoter, cds:-1112C>T, p.R130Q (c.389G>A) (rs1800925, rs20541) (human) RGD PMID:19220774 RGD:8549541 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
Eosinophilic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL26 C-C motif chemokine ligand 26 severity ISO protein:increased expression:sputum (human) RGD PMID:25936567 RGD:11531115 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726
JBrowse link
G EPX eosinophil peroxidase treatment ISO RGD PMID:28751233 RGD:13506890 NCBI chr 9:32,855,568...32,865,445
Ensembl chr 9:32,855,507...32,865,022
JBrowse link
eosinophilic esophagitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD27 ankyrin repeat domain 27 ISO DNA:SNPs:intron: (rs3815700, rs10410895) (human) RGD PMID:25407941 RGD:11100048 NCBI chr 1:119,325,132...119,377,266
Ensembl chr 1:119,325,873...119,376,948
JBrowse link
G B9D2 B9 domain containing 2 ISO RGD PMID:24486052 RGD:11073602 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G CAPN14 calpain 14 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:esophagus
DNA:snps:multiple (human)
CTD
RGD
PMID:25017104 PMID:25407941 RGD:11100048 RGD:11100049 NCBI chr17:24,774,603...24,812,719
Ensembl chr17:24,775,059...24,811,742
JBrowse link
G CCL26 C-C motif chemokine ligand 26 treatment ISO protein:increased expression:esophagus (human) RGD PMID:18844613 PMID:24704289 RGD:11081156 RGD:11081157 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:1316818 RGD:6893390 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217
JBrowse link
G CD40LG CD40 ligand ISO protein:decreased expression:plasma RGD PMID:21211656 RGD:5490306 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G IL5 interleukin 5 ISO RGD PMID:23161496 RGD:11354947 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:esophagus (human) RGD PMID:22331014 RGD:6771318 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778
JBrowse link
G TSLP thymic stromal lymphopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208534 NCBI chr 3:1,502,469...1,507,696
Ensembl chr 3:1,503,188...1,507,696
JBrowse link
exercise-induced bronchoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:10984370 RGD:4890423 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (human) RGD PMID:19996575 RGD:4892021 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:8630576 RGD:5147837 NCBI chr17:48,038,010...48,178,971
Ensembl chr17:48,038,010...48,178,971
JBrowse link
Experimental Allergic Asthma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL3 acyl-CoA synthetase long chain family member 3 ISO RGD PMID:23526225 RGD:13831300 NCBI chr37:28,882,264...28,929,451
Ensembl chr37:28,864,147...28,938,866
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G CD86 CD86 molecule treatment ISO RGD PMID:25344652 RGD:11354965 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:29713367 RGD:13792581 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224
JBrowse link
G IL23A interleukin 23 subunit alpha ISO RGD PMID:19935773 PMID:26344076 RGD:11251537 RGD:5037240 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359
JBrowse link
extrinsic allergic alveolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO protein:increased expression:plasma RGD PMID:19218674 RGD:4140920 NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (mouse)
mRNA:increased expression:lung:bronchoalveolar lavage cell (human)
RGD PMID:10384061 PMID:16387809 RGD:4891434 RGD:4891436 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO RGD PMID:20027288 RGD:5130978 NCBI chr 9:38,994,638...38,996,103
Ensembl chr 9:38,993,911...39,010,483
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:19842835 RGD:4145620 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217
JBrowse link
G CD86 CD86 molecule ISO associated with Paramyxoviridae Infections; protein:increased expression:lung (mouse) RGD PMID:19282343 RGD:4892294 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO mRNA:increased expression:alveolar macrophage RGD PMID:14991597 PMID:15725351 RGD:5135448 RGD:5135490 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979
JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 ISO RGD PMID:14991597 RGD:5135448 NCBI chr32:631,084...636,997
Ensembl chr32:631,478...632,868
Ensembl chr32:631,478...632,868
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:14991597 PMID:19842835 RGD:4145620 RGD:5135448 NCBI chr  X:55,882,433...55,884,582
Ensembl chr  X:55,882,433...55,884,582
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO mRNA:decreased expression:leukocyte RGD PMID:20514434 RGD:4892076 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754
JBrowse link
G IL13 interleukin 13 ISO mRNA:increased expression:lung RGD PMID:9916735 PMID:20861649 RGD:4145650 RGD:5128548 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL17A interleukin 17A ISO associated with Silicosis RGD PMID:19151189 PMID:20421647 RGD:4888525 RGD:4889106 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
JBrowse link
G IL17RA interleukin 17 receptor A ISO RGD PMID:19414809 RGD:5144217 NCBI chr27:44,798,960...44,812,287
Ensembl chr27:44,791,066...44,811,064
JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:10882225 RGD:4142832 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G IL1B interleukin 1 beta disease_progression ISO protein:increased expression:serum (human) RGD PMID:1519663 PMID:19556641 RGD:4142842 RGD:7401229 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G IL5 interleukin 5 ISO protein:increased expression:lung,respiratory system fluid/secretion RGD PMID:19151189 RGD:4889106 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269
JBrowse link
G LOC610540 pulmonary surfactant-associated protein A-like ISO protein:decreased expression:lung RGD PMID:10543276 RGD:4143437 NCBI chr 4:29,430,139...29,434,640 JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:lung RGD PMID:11789718 RGD:4891449 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10673208 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO DNA:polymorphisms:cds:P. D637G, P661P (human) RGD PMID:18342853 RGD:5147840 NCBI chr12:2,424,049...2,432,165
Ensembl chr12:2,378,126...2,432,303
JBrowse link
G TLR6 toll like receptor 6 ISO RGD PMID:20070409 RGD:4889532 NCBI chr 3:73,504,357...73,523,964
Ensembl chr 3:73,520,706...73,523,099
JBrowse link
G TNC tenascin C ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:9780295 RGD:4889595 NCBI chr11:69,077,532...69,169,673
Ensembl chr11:69,077,535...69,170,281
JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:10882225 PMID:15653992 RGD:4142832 RGD:4143466 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:alveolar macrophage (human) RGD PMID:15929959 RGD:5131148 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO protein:increased expression:alveolar macrophage (human) RGD PMID:15929959 RGD:5131148 NCBI chr 2:84,140,179...84,151,219
Ensembl chr 2:84,141,911...84,157,191
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:15764076 RGD:5684419 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
familial cold autoinflammatory syndrome 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP3 NLR family pyrin domain containing 3 ISO ClinVar Annotator: match by term: CRYOPYRIN-ASSOCIATED PERIODIC SYNDROME 1 | ClinVar Annotator: match by term: FAMILIAL COLD AUTOINFLAMMATORY SYNDROME 1 | ClinVar Annotator: match by term: Familial cold autoinflammatory syndrome 1 OMIM
ClinVar
PMID:49161 PMID:447320 PMID:5173311 PMID:11687797 PMID:11992256 More... NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059
JBrowse link
familial cold autoinflammatory syndrome 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference