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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Ovarian Neoplasms
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Accession:DOID:9002762 term browser browse the term
Definition:Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Synonyms:exact_synonym: ovarian neoplasm;   ovary neoplasm;   ovary neoplasms;   tumor of the ovary
 primary_id: MESH:D010051
 alt_id: RDO:0001423
For additional species annotation, visit the Alliance of Genome Resources.



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Ovarian Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO ClinVar Annotator: match by term: Ovarian Neoplasms ClinVar PMID:16467099 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 ISO ClinVar Annotator: match by term: Ovarian Neoplasms ClinVar PMID:16702730 PMID:16784736 PMID:18834626 PMID:19474787 PMID:19506252 More... NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian neoplasm
CTD
ClinVar
PMID:16211241 PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 More... NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609
JBrowse link
G AMH anti-Mullerian hormone ISO mRNA, protein:increased expression:ovary RGD PMID:19424576 RGD:2315638 NCBI chr20:56,785,960...56,788,815 JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 ISO mRNA, protein:increased expression:ovary RGD PMID:19424576 RGD:2315638 NCBI chr27:1,788,420...1,795,601
Ensembl chr27:1,789,681...1,795,533
JBrowse link
G ANXA3 annexin A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21435174 NCBI chr32:3,006,000...3,049,321
Ensembl chr32:3,005,788...3,049,049
JBrowse link
G AQP3 aquaporin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18214481 NCBI chr11:50,517,509...50,524,565 JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: therapeutic CTD PMID:15313392 NCBI chr13:62,925,761...62,936,753
Ensembl chr13:62,926,301...62,936,738
JBrowse link
G ATF3 activating transcription factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15674352 NCBI chr 7:10,784,445...10,795,285
Ensembl chr 7:10,782,064...10,794,163
JBrowse link
G ATG5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28408137 NCBI chr12:63,565,859...63,692,383
Ensembl chr12:63,567,568...63,683,485
JBrowse link
G ATG7 autophagy related 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28408137 NCBI chr20:6,916,354...7,154,849
Ensembl chr20:6,916,515...7,154,800
JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Ovarian Neoplasms ClinVar NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G ATP7B ATPase copper transporting beta severity ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12216079 RGD:2298865 NCBI chr22:162,474...225,599
Ensembl chr22:191,888...225,266
JBrowse link
G BABAM1 BRISC and BRCA1 A complex member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852633 NCBI chr20:45,466,808...45,474,953
Ensembl chr20:45,466,805...45,473,009
JBrowse link
G BAP1 BRCA1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr20:37,355,499...37,364,298
Ensembl chr20:37,355,494...37,511,125
JBrowse link
G BARD1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Ovarian Neoplasms ClinVar NCBI chr37:21,946,770...22,024,672
Ensembl chr37:21,948,456...22,024,867
JBrowse link
G BCL2 BCL2 apoptosis regulator severity ISO RGD PMID:18006758 RGD:2298897 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BCL2L1 BCL2 like 1 ISO RGD PMID:17675586 RGD:1643478 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355
JBrowse link
G BCL9 BCL9 transcription coactivator ISO CTD Direct Evidence: marker/mechanism CTD PMID:22024689 NCBI chr17:58,105,914...58,189,065
Ensembl chr17:58,168,375...58,189,062
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:15970709 PMID:16202317 PMID:16211241 PMID:18171606 PMID:18567002 RGD:2298935 RGD:2298936 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BNC2 basonuclin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852632 NCBI chr11:36,511,581...36,950,111
Ensembl chr11:36,514,166...36,950,679
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Ovarian Neoplasms
DNA:missense mutation:exon:p.V599E (human)
RGD
ClinVar
PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... RGD:2298686 RGD:2315855 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian neoplasm
CTD
ClinVar
PMID:7611277 PMID:7663517 PMID:7795652 PMID:7837387 PMID:7894491 More... NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494
JBrowse link
G BRCA2 BRCA2 DNA repair associated susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian neoplasm
CTD
ClinVar
RGD
PMID:8075631 PMID:8524414 PMID:8589730 PMID:8673091 PMID:8673092 More... RGD:1599505 NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815
JBrowse link
G BRIP1 BRCA1 interacting helicase 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian neoplasm
ClinVar Annotator: match by term: Ovarian cancer
DNA:snps:introns:c.2158-13912A>C, c.508-31C>G (rs2191249,rs4988344) (human)
CTD
ClinVar
RGD
PMID:9536098 PMID:11301010 PMID:12565990 PMID:12569564 PMID:12872252 More... RGD:11251782 NCBI chr 9:34,804,285...34,984,640
Ensembl chr 9:34,806,535...34,983,788
JBrowse link
G C1H19orf12 chromosome 1 C19orf12 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:21397856 NCBI chr 1:121,823,827...121,838,242
Ensembl chr 1:121,758,236...121,766,652
Ensembl chr 1:121,758,236...121,766,652
JBrowse link
G CADM1 cell adhesion molecule 1 severity ISO DNA:hypermethylation RGD PMID:16532039 RGD:2296030 NCBI chr 5:17,865,317...18,190,855
Ensembl chr 5:17,864,453...18,194,694
JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28634229 NCBI chr26:7,848,191...7,895,317
Ensembl chr26:7,847,466...7,893,410
JBrowse link
G CAV1 caveolin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:15674352 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935
JBrowse link
G CCL5 C-C motif chemokine ligand 5 severity ISO RGD PMID:20400704 RGD:4891397 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852
JBrowse link
G CCND2 cyclin D2 disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA:hypermethylation:promoter
CTD
RGD
PMID:17270028 RGD:2296038 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255
JBrowse link
G CCNE1 cyclin E1 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:ovary
protein:alternative forms, increased expression:ovary
CTD
RGD
PMID:16116079 PMID:17647260 PMID:21397856 RGD:2289287 RGD:2296042 NCBI chr 1:121,688,622...121,697,533
Ensembl chr 1:121,688,796...121,697,649
JBrowse link
G CCNH cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 3:21,046,477...21,067,305
Ensembl chr 3:21,046,472...21,178,315
JBrowse link
G CD40LG CD40 ligand disease_progression ISO RGD PMID:20400704 RGD:4891397 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CD44 CD44 molecule ISO mRNA:splice variants:ovary RGD PMID:18091389 RGD:2289345 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107
JBrowse link
G CDH1 cadherin 1 susceptibility ISO DNA:polymorphism:3' utr:*54C>T (human)
ClinVar Annotator: match by term: Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:8075649 PMID:15785075 PMID:18035404 PMID:19139070 PMID:22470475 More... RGD:2289494 RGD:2289497 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G CDK2 cyclin dependent kinase 2 disease_progression ISO protein:increased expression:ovary
DNA, mRNA:amplification, increased expression:ovary
RGD PMID:9426687 PMID:11585414 RGD:2298988 RGD:2298989 NCBI chr10:300,863...306,546
Ensembl chr10:300,903...305,438
JBrowse link
G CDK4 cyclin dependent kinase 4 ISO RGD PMID:17692085 RGD:2299054 NCBI chr10:1,812,864...1,815,815
Ensembl chr10:1,812,886...1,815,789
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:decreased expression:ovary RGD PMID:9006333 RGD:2289661 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:ovary
CTD
RGD
PMID:11376116 PMID:16391232 RGD:2293610 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO DNA, mRNA:hypermethylation, decreased expression:promoter, ovary RGD PMID:16000597 RGD:2296065 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CHEK2 checkpoint kinase 2 susceptibility ISO DNA:loss of heterozygosity
DNA:missense mutation:cds:p.I157T
RGD PMID:16828850 PMID:17145815 RGD:2289706 RGD:2298482 NCBI chr26:22,052,256...22,145,675
Ensembl chr26:21,427,961...22,240,624
JBrowse link
G CHMP4C charged multivesicular body protein 4C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23535730 PMID:31043753 NCBI chr29:28,839,459...28,865,793
Ensembl chr29:28,839,516...28,865,023
JBrowse link
G CTNNA1 catenin alpha 1 ISO protein:decreased expression:ovary RGD PMID:9522220 RGD:2289798 NCBI chr11:26,273,322...26,459,497
Ensembl chr11:26,143,013...26,459,091
JBrowse link
G CTNNB1 catenin beta 1 disease_progression ISO ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian cancer
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:9065403 PMID:10027390 PMID:10192393 PMID:10391090 PMID:11351304 More... RGD:2298487 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19401270 PMID:21742513 NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17372243 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554
JBrowse link
G DESI2 desumoylating isopeptidase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:21667029 NCBI chr 7:35,688,519...35,734,283
Ensembl chr 7:35,687,888...35,731,186
JBrowse link
G DLC1 DLC1 Rho GTPase activating protein ISO CTD Direct Evidence: therapeutic CTD PMID:15674352 NCBI chr16:36,531,754...36,943,033
Ensembl chr16:36,531,754...36,943,033
JBrowse link
G DNMT1 DNA methyltransferase 1 susceptibility ISO DNA:SNPs: :rs2228611,rs759920 (human) RGD PMID:23666104 RGD:9588645 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DOK1 docking protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21856257 NCBI chr17:48,588,579...48,591,523
Ensembl chr17:48,589,023...48,591,721
JBrowse link
G DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20857490 NCBI chr 1:113,644,191...113,652,441
Ensembl chr 1:113,644,100...113,828,488
JBrowse link
G EDNRA endothelin receptor type A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25194819 NCBI chr15:45,823,472...45,878,527
Ensembl chr15:45,823,560...45,876,463
JBrowse link
G EGFR epidermal growth factor receptor severity ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:mammary tumor cell, nucleus (human)
protein:decreased expression:ovary
CTD
RGD
PMID:16211241 PMID:18575766 PMID:19058255 PMID:21909139 RGD:2298499 RGD:5131867 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G EPCAM epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20870202 NCBI chr10:49,446,165...49,498,690
Ensembl chr10:49,485,746...49,498,475
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian cancer
mRNA, protein:increased expression:ovary
DNA, protein:amplification, increased expression:ovary
CTD
ClinVar
RGD
PMID:10897039 PMID:15457249 PMID:17987122 PMID:18339846 PMID:18575766 More... RGD:2289928 RGD:2298499 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO mRNA, protein:increased expression:ovary RGD PMID:16896008 PMID:18575766 RGD:2298499 RGD:2298501 NCBI chr10:406,856...424,746
Ensembl chr10:406,633...424,264
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO mRNA, protein:increased expression:ovary RGD PMID:18575766 RGD:2298499 NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit disease_progression ISO DNA:SNP: :rs1799793(human) RGD PMID:25881102 RGD:11252176 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125
JBrowse link
G EREG epiregulin ISO CTD Direct Evidence: therapeutic CTD PMID:15313392 NCBI chr13:62,857,325...62,877,831
Ensembl chr13:62,856,709...62,877,760
JBrowse link
G FANCF FA complementation group F disease_progression ISO DNA, mRNA, protein:hypermethylation, decreased expression:ovary
DNA:hypermethylation:promoter
RGD PMID:16418574 PMID:18414472 RGD:2290044 RGD:2298507 NCBI chr21:44,253,308...44,256,221
Ensembl chr21:44,255,134...44,256,618
JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21442130 NCBI chr 9:233,105...249,573
Ensembl chr 9:232,963...249,092
JBrowse link
G FGF1 fibroblast growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25174399 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619
JBrowse link
G FGF8 fibroblast growth factor 8 ISO mRNA,protein:increased expression:ovary RGD PMID:11072239 RGD:2289342 NCBI chr28:14,362,407...14,367,109
Ensembl chr28:14,362,109...14,367,468
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO epithelial ovarian cancer (OMIM:604370); mRNA:increased expression:ovary RGD PMID:11593393 RGD:2289733 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO mRNA,DNA:alternative form,loss of heterozygosity::abnormal transcript in 2/54 cases (4%), LOH in 8/54 cases (15%) RGD PMID:9569038 RGD:2289905 NCBI chr20:29,735,380...31,113,859
Ensembl chr20:30,356,572...31,113,859
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO protein:increased expression:ovarian epithelial carcinoma RGD PMID:11448924 PMID:11929819 PMID:15350351 RGD:2289945 RGD:2301253 RGD:2301254 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621
JBrowse link
G FSHR follicle stimulating hormone receptor ISO sex cord-stromal tumors;DNA:point mutation:F591S RGD PMID:9100567 RGD:1601234 NCBI chr10:50,765,591...50,938,643
Ensembl chr10:50,770,995...50,938,474
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: therapeutic CTD PMID:17474084 NCBI chr 6:77,393,026...77,396,473
Ensembl chr 6:77,393,036...77,396,618
JBrowse link
G GPR150 G protein-coupled receptor 150 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17303177
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr12:58,932,754...59,991,305
Ensembl chr12:59,355,017...59,990,408
JBrowse link
G GSK3B glycogen synthase kinase 3 beta severity ISO protein:increased expression:ovary (human) RGD PMID:22455883 RGD:13441553 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666
JBrowse link
G HAUS6 HAUS augmin like complex subunit 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043753 NCBI chr11:38,889,977...38,935,396
Ensembl chr11:38,893,544...38,935,136
JBrowse link
G HDAC1 histone deacetylase 1 disease_progression ISO protein:increased expression:ovary RGD PMID:17387270 PMID:18714364 RGD:2306205 RGD:2306215 NCBI chr 2:68,901,339...68,936,473
Ensembl chr 2:68,901,651...68,936,186
JBrowse link
G HDAC2 histone deacetylase 2 disease_progression ISO protein:increased expression:ovary RGD PMID:17387270 PMID:18714364 RGD:2306205 RGD:2306215 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578
JBrowse link
G HDAC6 histone deacetylase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19010849 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain ISO DNA:amplification, deletion RGD PMID:18561316 RGD:2306229 NCBI chr12:2,151,409...2,164,564 JBrowse link
G HOXB9 homeobox B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27182052 NCBI chr 9:24,884,101...24,889,904
Ensembl chr 9:24,872,950...24,889,376
JBrowse link
G HOXD1 homeobox D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852632 NCBI chr36:19,995,326...19,997,059
Ensembl chr36:19,995,323...19,997,072
JBrowse link
G HOXD11 homeobox D11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17303177 NCBI chr36:19,913,064...19,926,868
Ensembl chr36:19,914,431...19,916,766
JBrowse link
G HOXD9 homeobox D9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26075790 NCBI chr36:19,929,479...19,932,861 JBrowse link
G HRAS HRas proto-oncogene, GTPase onset ISO protein:increased expression:endometrial stroma (human) RGD PMID:9641239 RGD:13441555 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, ovary RGD PMID:16445635 PMID:17332286 RGD:2301467 RGD:2301468 NCBI chr16:1,021,855...1,027,604
Ensembl chr16:1,021,972...1,026,392
JBrowse link
G IL11RA interleukin 11 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11161848 NCBI chr11:51,324,915...51,341,981 JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19401270 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:11161848 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124
JBrowse link
G INHA inhibin subunit alpha ISO protein:increased expression:tumors RGD PMID:10435065 RGD:2290383 NCBI chr37:26,080,465...26,083,570
Ensembl chr37:26,080,510...26,083,391
JBrowse link
G ITGA8 integrin subunit alpha 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17303177 NCBI chr 2:21,034,630...21,244,304
Ensembl chr 2:21,075,653...21,241,951
JBrowse link
G JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30619488 NCBI chr 9:4,037,307...4,076,119
Ensembl chr 9:4,037,439...4,076,123
JBrowse link
G KANSL1 KAT8 regulatory NSL complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043753 Ensembl chr 9:9,381,737...9,565,976
Ensembl chr 9:9,381,737...9,565,976
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:epithelial ovarian carcinoma cells RGD PMID:16835828 RGD:2291926 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase disease_progression ISO advanced serous ovarian carcinoma; protein:increased expression:tumor:expression correlated with disease progression after first-line chemotherapy (i.e. chemotherapy resistance), p=0.029 RGD PMID:15033665 RGD:2292422 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G KLK10 kallikrein related peptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20686372 NCBI chr 1:105,860,406...105,864,238
Ensembl chr 1:105,860,946...105,864,238
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian neoplasm
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:6320174 More... RGD:2314911 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO mRNA:decreased expression:ovary RGD PMID:11994539 RGD:2289157 NCBI chr10:50,540,706...50,594,336
Ensembl chr10:50,541,960...50,598,036
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase disease_progression ISO protein:increased expression:ovary RGD PMID:7446622 PMID:15907336 RGD:2314920 RGD:2314924 NCBI chr 3:12,668,994...12,766,712
Ensembl chr 3:12,681,577...12,767,183
JBrowse link
G LOC100856382 matrix Gla protein ISO mRNA:increased expression:tumor:39/39 (100%) of tumors showed >10x increase over normal tissue and 87% showed >100x increase RGD PMID:11358798 RGD:2293586 NCBI chr27:31,735,301...31,738,673
Ensembl chr27:31,734,660...31,738,673
JBrowse link
G LOC479902 methylosome protein 50 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22022581 NCBI chr 6:40,626,219...40,634,521
Ensembl chr 6:40,624,886...40,635,200
JBrowse link
G LOC609365 CD46 molecule, complement regulatory protein-like disease_progression ISO RGD PMID:12183422 PMID:15726105 PMID:17214367 RGD:2306065 RGD:2306066 RGD:2306067 NCBI chr 7:6,602,762...6,646,561 JBrowse link
G LOC609612 folate receptor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:17466904 NCBI chr21:25,944,350...25,951,010 JBrowse link
G LOC611363 mesothelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11751476 NCBI chr 6:39,827,985...39,834,945 JBrowse link
G LRRC46 leucine rich repeat containing 46 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043753 NCBI chr 9:24,162,775...24,168,183
Ensembl chr 9:24,162,898...24,168,151
JBrowse link
G LRRC59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 9:26,350,300...26,364,021
Ensembl chr 9:26,351,734...26,364,082
JBrowse link
G MACIR macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 3:7,956,865...7,968,964 JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO RGD PMID:18060073 RGD:2298686 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO RGD PMID:18060073 RGD:2298686 NCBI chr20:55,465,460...55,487,629
Ensembl chr20:55,465,212...55,487,641
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 disease_progression ISO expression inhibits metastatic colonization of secondary sites by cancer cells in the SKOV3ip.1 cell line model system RGD PMID:16489030 RGD:2293338 NCBI chr 5:36,142,610...36,243,673
Ensembl chr 5:36,118,388...36,241,296
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 no_association ISO expression has no effect on metastatic colonization of secondary sites by cancer cells in the SKOV3ip.1 cell line model system RGD PMID:16489030 RGD:2293338 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO ClinVar Annotator: match by term: Ovarian Neoplasms ClinVar NCBI chr 2:43,918,210...43,996,817
Ensembl chr 2:43,917,604...43,995,209
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16211241 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16211241 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G MCPH1 microcephalin 1 severity ISO protein:decreased expression:ovary, nucleus
mRNA:decreased expression:ovary (human)
RGD PMID:16872911 PMID:24830737 RGD:13204746 RGD:9589035 NCBI chr16:58,306,761...58,529,090
Ensembl chr16:58,295,280...58,529,433
JBrowse link
G MECOM MDS1 and EVI1 complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:23770046 NCBI chr34:33,747,495...34,299,389
Ensembl chr34:33,748,843...34,299,276
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20661229 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027
JBrowse link
G MKI67 marker of proliferation Ki-67 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21442130 NCBI chr28:36,920,679...36,939,336
Ensembl chr28:36,913,023...36,939,486
JBrowse link
G MLH1 mutL homolog 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19032668 NCBI chr23:6,889,108...6,938,117
Ensembl chr23:6,889,135...6,938,116
JBrowse link
G MMP2 matrix metallopeptidase 2 susceptibility ISO DNA:SNP:promoter:-735C>T RGD PMID:18424416 RGD:2298519 NCBI chr 2:60,471,092...60,492,991
Ensembl chr 2:60,471,257...60,494,113
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease ISO ClinVar Annotator: match by term: Ovarian neoplasm ClinVar PMID:25741868 PMID:28492532 NCBI chr21:6,448,909...6,528,185
Ensembl chr21:6,449,822...6,527,119
JBrowse link
G MSH2 mutS homolog 2 ISO ClinVar Annotator: match by term: Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:9777949 PMID:10375096 PMID:10413423 PMID:15713769 PMID:15849733 More... RGD:2298950 NCBI chr10:49,517,448...49,594,001
Ensembl chr10:49,517,369...49,594,210
JBrowse link
G MSH6 mutS homolog 6 ISO ClinVar Annotator: match by term: Ovarian Neoplasms ClinVar PMID:18269114 PMID:24362816 PMID:28492532 NCBI chr10:49,825,330...49,838,036
Ensembl chr10:49,803,898...49,838,028
JBrowse link
G MSR1 macrophage scavenger receptor 1 disease_progression ISO RGD PMID:17510407 RGD:2306128 NCBI chr16:39,434,948...39,513,727
Ensembl chr16:39,436,753...39,527,438
JBrowse link
G MT-CYB mitochondrially encoded cytochrome b ISO ClinVar Annotator: match by term: Ovarian cancer
ClinVar Annotator: match by term: Ovarian neoplasm
ClinVar PMID:24667782 PMID:25741868 NCBI chr MT:14,183...15,322
Ensembl chr MT:14,183...15,322
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20138251 PMID:30705370 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114
JBrowse link
G MUC16 mucin 16, cell surface associated ISO CTD Direct Evidence: therapeutic CTD PMID:11706781 NCBI chr20:51,790,036...51,876,801 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852632 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309
JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: therapeutic CTD PMID:23758976 NCBI chr 1:110,543,140...110,569,168
Ensembl chr 1:110,543,247...110,569,143
JBrowse link
G NME2 non-metastatic cells 2, protein (NM23B) expressed in ISO CTD Direct Evidence: therapeutic CTD PMID:15674352 NCBI chr 9:27,002,114...27,005,740
Ensembl chr 9:27,001,733...27,015,934
JBrowse link
G OPCML opioid binding protein/cell adhesion molecule like ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian cancer
CTD
ClinVar
PMID:12819783 NCBI chr 5:2,175,002...2,725,878
Ensembl chr 5:2,175,075...2,655,602
JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO DNA:amplification RGD PMID:16753589 RGD:2299166 NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha disease_progression ISO protein:decreased expression:ovary
protein:increased expression:ovary, epithelial cell
RGD PMID:8402626 PMID:15791568 RGD:2292199 RGD:2298578 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO protein:increased expression:ovary RGD PMID:15791568 RGD:2298578 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283
JBrowse link
G PHB prohibitin no_association ISO DNA:polymorphism:3' utr:1703C>T RGD PMID:12821355 RGD:2292403 NCBI chr 9:25,525,711...25,536,722
Ensembl chr 9:25,526,649...25,536,722
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian epithelial cancer
ClinVar Annotator: match by term: Ovarian cancer
ClinVar Annotator: match by term: Ovarian neoplasm
CTD
ClinVar
PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910
JBrowse link
G PLEKHF1 pleckstrin homology and FYVE domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21397856 NCBI chr 1:121,776,122...121,802,881
Ensembl chr 1:121,781,181...121,782,578
Ensembl chr 1:121,781,181...121,782,578
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component ISO ClinVar Annotator: match by term: Ovarian neoplasm ClinVar PMID:10480359 PMID:15256438 PMID:16472587 PMID:19132747 PMID:19526325 More... NCBI chr 6:11,411,062...11,438,767
Ensembl chr 6:11,349,453...11,438,940
JBrowse link
G POP4 POP4 homolog, ribonuclease P/MRP subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21397856 NCBI chr 1:121,809,448...121,815,811
Ensembl chr 1:121,809,701...121,815,443
JBrowse link
G PPP1CC protein phosphatase 1 catalytic subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:21397856 NCBI chr26:8,497,350...8,518,467
Ensembl chr26:8,495,067...8,518,675
JBrowse link
G PRC1 protein regulator of cytokinesis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043753 NCBI chr 3:53,252,893...53,279,717
Ensembl chr 3:53,253,626...53,279,211
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian cancer
ClinVar Annotator: match by term: Ovarian neoplasm
CTD
ClinVar
PMID:10072423 PMID:11558785 PMID:11889248 PMID:12629236 PMID:12719539 More... NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G PRTFDC1 phosphoribosyl transferase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17303177 NCBI chr 2:8,551,008...8,643,710
Ensembl chr 2:8,559,319...8,642,533
JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian neoplasm
CTD Direct Evidence: marker/mechanism
RGD
ClinVar
CTD
PMID:9140396 PMID:9241266 PMID:9259288 PMID:9399897 PMID:9467011 More... RGD:2289817 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:15867369 RGD:2300208 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression ISO protein:increased expression:ovary RGD PMID:14766256 PMID:18171606 RGD:2298936 RGD:2300209 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G RAD51C RAD51 paralog C ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian neoplasm
CTD
ClinVar
PMID:20400963 PMID:20400964 PMID:21616938 PMID:21990120 PMID:22006311 More... NCBI chr 9:33,289,675...33,347,411
Ensembl chr 9:33,289,742...33,326,405
JBrowse link
G RAD51D RAD51 paralog D ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
CTD
ClinVar
PMID:20665887 PMID:21822267 PMID:22652533 PMID:22986143 PMID:24130102 More... NCBI chr 9:38,242,178...38,259,788
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
G RB1 RB transcriptional corepressor 1 disease_progression
susceptibility
ISO ClinVar Annotator: match by term: Ovarian neoplasm
DNA:SNPs
RGD
ClinVar
PMID:16510568 PMID:17047088 PMID:17242700 PMID:25741868 PMID:28492532 RGD:2296051 RGD:2299894 RGD:2299895 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726
JBrowse link
G RBL2 RB transcriptional corepressor like 2 ISO CTD Direct Evidence: therapeutic CTD PMID:16936753 NCBI chr 2:62,263,974...62,315,371
Ensembl chr 2:62,265,293...62,315,425
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit disease_progression ISO RGD PMID:18314621 RGD:2298752 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875
JBrowse link
G RRAS2 RAS related 2 ISO ClinVar Annotator: match by term: Ovarian neoplasm ClinVar PMID:8052619 PMID:25741868 PMID:31130282 PMID:31130285 NCBI chr21:37,037,576...37,119,733
Ensembl chr21:37,038,334...37,112,662
JBrowse link
G SELENBP1 selenium binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16380993 PMID:18272210 NCBI chr17:60,410,727...60,418,770
Ensembl chr17:60,410,734...60,418,704
JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852632 NCBI chr 9:24,412,820...24,700,579
Ensembl chr 9:24,412,820...24,700,734
JBrowse link
G SKP2 S-phase kinase associated protein 2 disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:16525656 PMID:19636294 RGD:2315042 NCBI chr 4:72,352,966...72,386,469
Ensembl chr 4:72,352,986...72,386,307
JBrowse link
G SLC22A10 solute carrier family 22 member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr18:53,597,148...53,628,569
Ensembl chr18:53,597,533...53,628,165
JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20138251 NCBI chr15:463,307...493,145
Ensembl chr15:463,237...493,140
JBrowse link
G SLC5A5 solute carrier family 5 member 5 ISO CTD Direct Evidence: therapeutic CTD PMID:12489024 NCBI chr20:45,017,939...45,030,598
Ensembl chr20:45,018,119...45,030,209
JBrowse link
G SMAD6 SMAD family member 6 ISO DNA:polymorphism:intron (human) RGD PMID:11078792 RGD:2300008 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583
JBrowse link
G SMAD7 SMAD family member 7 ISO DNA:polymorphism:cds RGD PMID:11078792 RGD:2300008 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749
JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24658001 PMID:24658002 PMID:24658004 PMID:26343384 NCBI chr20:50,175,489...50,268,865
Ensembl chr20:50,175,687...50,268,836
JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16179351 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16179351 PMID:18594523 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17951402 PMID:19177197 RGD:2300019 NCBI chr 4:57,659,541...57,682,147
Ensembl chr 4:57,659,650...57,681,711
JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18567002 NCBI chr12:3,814,806...3,831,724
Ensembl chr12:3,815,300...3,831,477
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:16428483 RGD:1581364 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO mRNA:increased expression:epithelium of female gonad (human) RGD PMID:23748175 RGD:11039469 NCBI chr 9:32,692,517...32,696,325
Ensembl chr 9:32,694,073...32,696,285
JBrowse link
G SRSF10 serine and arginine rich splicing factor 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21072693 NCBI chr 2:75,587,561...75,601,099
Ensembl chr 2:75,587,584...75,598,925
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:ovary RGD PMID:16439987 RGD:2315091 NCBI chr 5:4,652,493...4,666,728
Ensembl chr 5:4,651,863...4,691,069
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:ovary
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15771796 PMID:21909139 RGD:2291931 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672
JBrowse link
G SULF1 sulfatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17310998 NCBI chr29:18,709,406...18,885,248
Ensembl chr29:18,709,445...18,884,378
JBrowse link
G SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 ISO DNA:SNP::reduced frequency of SULT1A1*2 A allele in patients RGD PMID:18497059 RGD:2301045 NCBI chr 6:18,176,156...18,179,492
Ensembl chr 6:18,176,355...18,179,489
JBrowse link
G TERT telomerase reverse transcriptase ISO protein:increased activity:ovary
mRNA:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10652422 PMID:17273731 PMID:23535731 RGD:2291989 RGD:2298564 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 disease_progression ISO protein:increased expression:ovary RGD PMID:17009974 RGD:2290414 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288
JBrowse link
G TIPARP TCDD inducible poly(ADP-ribose) polymerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852632 NCBI chr23:50,253,645...50,279,615
Ensembl chr23:50,249,327...50,280,144
JBrowse link
G TLR4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21616060 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:21616060 NCBI chr34:36,719,249...36,734,989
Ensembl chr34:36,670,849...36,735,060
JBrowse link
G TOP2A DNA topoisomerase II alpha disease_progression ISO RGD PMID:19270648 RGD:2315125 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ovarian Neoplasms
ClinVar Annotator: match by term: Ovarian neoplasm
CTD
ClinVar
PMID:1349102 PMID:1349175 PMID:1565143 PMID:1565144 PMID:1591732 More... NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr30:10,263,650...10,362,646
Ensembl chr30:10,263,650...10,336,134
JBrowse link
G TP63 tumor protein p63 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:alternative form (human)
CTD
RGD
PMID:17998283 PMID:21266360 RGD:2315432 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046
JBrowse link
G TP73 tumor protein p73 disease_progression ISO protein:increased expression:ovary
DNA:loss of heterozygosity:ovary
RGD PMID:10760569 PMID:11051237 PMID:12928725 RGD:2291833 RGD:2291834 RGD:2298530 NCBI chr 5:58,194,385...58,241,159
Ensembl chr 5:58,187,826...58,240,839
JBrowse link
G TRMT11 tRNA methyltransferase 11 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 1:64,861,404...64,917,449
Ensembl chr 1:64,834,770...65,064,562
JBrowse link
G TYMS thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21795601 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747
JBrowse link
G URI1 URI1 prefoldin like chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:21397856 NCBI chr 1:121,528,706...121,612,200
Ensembl chr 1:121,530,203...121,614,909
JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression ISO DNA:polymorphisms: :405G>C, -460C>T (human) RGD PMID:19509553 RGD:2315464 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G WNT7A Wnt family member 7A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25174399 NCBI chr20:4,072,010...4,139,521
Ensembl chr20:4,073,929...4,139,436
JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19758744 PMID:21442130 RGD:2315847 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582
JBrowse link
G YAP1 Yes1 associated transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20947521 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18622689 NCBI chr 2:15,300,401...15,481,535
Ensembl chr 2:15,299,723...15,481,495
JBrowse link
dysgerminoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMHR2 anti-Mullerian hormone receptor type 2 ISO protein:increased expression:ovary RGD PMID:17988723 RGD:2315651 NCBI chr27:1,788,420...1,795,601
Ensembl chr27:1,789,681...1,795,533
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO ClinVar Annotator: match by term: Dysgerminoma ClinVar PMID:9150151 PMID:11376024 PMID:16683254 PMID:19491284 PMID:20104584 More... NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO associated with Acrocephalosyndactylia/Apert Syndrome (MeSH:D000168); DNA:transversion,duplication:cds:758C>G amino acid P253R, duplication of 10q26 resulting in one extra copy of FGFR2 RGD PMID:17243131 RGD:2289660 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621
JBrowse link
G INHA inhibin subunit alpha ISO protein:increased expression:tumor RGD PMID:11720904 RGD:2290380 NCBI chr37:26,080,465...26,083,570
Ensembl chr37:26,080,510...26,083,391
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO DNA:transversion:CDS:2467G>C, amino acid D816H
ClinVar Annotator: match by term: Dysgerminoma
RGD
ClinVar
PMID:7479840 PMID:7530509 PMID:7691885 PMID:8589724 PMID:9438854 More... RGD:2292181 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G SET SET nuclear proto-oncogene ISO ClinVar Annotator: match by term: Dysgerminoma ClinVar PMID:26822237 NCBI chr 9:54,896,464...54,907,698 JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:ovary RGD PMID:16439987 RGD:2315091 NCBI chr 5:4,652,493...4,666,728
Ensembl chr 5:4,651,863...4,691,069
JBrowse link
endometrial adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 ISO protein:increased expression:endometrium epithelium RGD PMID:17295646 RGD:2293852 NCBI chr13:8,068,920...8,312,090
Ensembl chr13:8,048,205...8,311,618
JBrowse link
G ANGPT2 angiopoietin 2 ISO protein:increased expression:endometrium epithelium RGD PMID:17295646 RGD:2293852 NCBI chr16:58,404,049...58,458,344
Ensembl chr16:58,405,259...58,457,701
JBrowse link
G ARID1A AT-rich interaction domain 1A treatment ISO human cell in mouse model RGD PMID:21900401 RGD:126725086 NCBI chr 2:73,331,606...73,401,151
Ensembl chr 2:73,324,852...73,401,102
JBrowse link
G AXIN2 axin 2 ISO RGD PMID:11940574 RGD:13432156 NCBI chr 9:14,559,476...14,588,950
Ensembl chr 9:14,559,388...14,588,530
JBrowse link
G BET1L Bet1 golgi vesicular membrane trafficking protein like disease_progression ISO RGD PMID:28654152 RGD:14394612 NCBI chr18:25,358,517...25,361,944
Ensembl chr18:25,360,636...25,361,299
JBrowse link
G CD55 CD55 molecule ISO RGD PMID:11506079 RGD:2326173 NCBI chr 7:6,361,037...6,396,063
Ensembl chr 7:6,360,964...6,386,226
JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 ISO protein:increased expression:endometrium RGD PMID:16112719 RGD:2289850 NCBI chr13:10,081,700...10,099,737
Ensembl chr13:10,081,695...10,099,501
JBrowse link
G FOXO3 forkhead box O3 severity ISO associated with Obesity;protein:decreased expression:endometrium (human) RGD PMID:26045339 RGD:11530998 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198
JBrowse link
G GPX3 glutathione peroxidase 3 ISO mRNA:decreased expression:endometrium (rat) RGD PMID:19426485 RGD:2312621 NCBI chr 4:58,200,671...58,209,010
Ensembl chr 4:58,200,672...58,209,010
JBrowse link
G IRF1 interferon regulatory factor 1 ISO DNA:deletions (rat) RGD PMID:19075038 RGD:5128782 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit no_association ISO protein, mRNA::endometrial epithelium and stroma:no correlation between expression and type of tissue or cancer stage or grade RGD PMID:10684716 RGD:2290482 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO DNA:point mutation:CDS:p.G12D, p.G12S, p.Q61H (rat) RGD PMID:10775052 RGD:1600499 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO protein:decreased phosphorylation:endometrium (human)
human tumor in a mouse model
RGD PMID:14760076 PMID:23402905 RGD:13703125 RGD:13703137 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO human tumor in a mouse model
protein:decreased phosphorylation:endometrium (human)
RGD PMID:14760076 PMID:23402905 RGD:13703125 RGD:13703137 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO DNA:mutations:multiple (human) RGD PMID:21478295 RGD:13441595 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970
JBrowse link
G PTEN phosphatase and tensin homolog ameliorates ISO RGD PMID:32843721 RGD:127285600 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176
JBrowse link
G PTGES prostaglandin E synthase ISO protein:increased expression:endometrium RGD PMID:11592775 RGD:2300089 NCBI chr 9:54,071,472...54,082,232
Ensembl chr 9:54,071,472...54,082,232
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO DNA:amplification (rat) RGD PMID:15942940 RGD:2324953 NCBI chr17:7,106,515...7,113,868
Ensembl chr17:7,104,961...7,122,939
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO mRNA:decreased expression:endometrium RGD PMID:15745937 RGD:1579943 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121
JBrowse link
G TP53 tumor protein p53 disease_progression ISO DNA:missense mutations
protein:increased expression:endometrium
RGD PMID:1540970 RGD:2290541 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G TSG101 tumor susceptibility 101 ISO mRNA:alternative forms RGD PMID:10027311 RGD:2291854 NCBI chr21:40,910,870...40,952,922
Ensembl chr21:40,910,874...40,952,808
JBrowse link
endometrial serous adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Endometrial serous adenocarcinoma ClinVar NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G BRCA2 BRCA2 DNA repair associated susceptibility ISO DNA:deletion: :6174delT RGD PMID:16650962 RGD:2289045 NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815
JBrowse link
Endometrioid Carcinomas term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G APC APC regulator of WNT signaling pathway ISO DNA:hypermethylation: (human) RGD PMID:18570730 RGD:13432144 NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993
JBrowse link
G AREG amphiregulin ISO mRNA, protein:increased expression:endometrium RGD PMID:16962163 RGD:2289950 NCBI chr13:62,925,761...62,936,753
Ensembl chr13:62,926,301...62,936,738
JBrowse link
G ATP7B ATPase copper transporting beta disease_progression ISO protein:increased expression:endometrium RGD PMID:15790435 RGD:2298864 NCBI chr22:162,474...225,599
Ensembl chr22:191,888...225,266
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO protein:increased expression:endometrium RGD PMID:16803539 RGD:2298940 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BMP4 bone morphogenetic protein 4 ISO RGD PMID:12782598 RGD:2296026 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G CA9 carbonic anhydrase 9 ISO protein:altered localization:membrane, endometrium RGD PMID:17452774 RGD:2298945 NCBI chr11:52,205,619...52,211,281
Ensembl chr11:52,205,668...52,211,267
JBrowse link
G CCNE1 cyclin E1 ISO protein:increased expression:endometrium RGD PMID:17483252 RGD:2289230 NCBI chr 1:121,688,622...121,697,533
Ensembl chr 1:121,688,796...121,697,649
JBrowse link
G CDH1 cadherin 1 ISO protein:decreased expression:endometrium RGD PMID:18295959 RGD:2296045 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G CDK2 cyclin dependent kinase 2 severity ISO RGD PMID:9673386 RGD:2298990 NCBI chr10:300,863...306,546
Ensembl chr10:300,903...305,438
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:17985331 RGD:2299091 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906
JBrowse link
G CHEK2 checkpoint kinase 2 susceptibility ISO RGD PMID:17164260 RGD:2293868 NCBI chr26:22,052,256...22,145,675
Ensembl chr26:21,427,961...22,240,624
JBrowse link
G CTNNB1 catenin beta 1 ISO DNA:mutations RGD PMID:17418409 RGD:2289817 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G DAXX death domain associated protein ISO protein:increased expression:ovary: RGD PMID:23539629 RGD:9587820 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA,protein:increased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029
JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO mRNA,protein:increased expression:uterus: RGD PMID:15721400 RGD:9588596 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900
JBrowse link
G EGFR epidermal growth factor receptor ISO mRNA:decreased expression:endometrium
ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation
RGD
ClinVar
PMID:16962163 PMID:22885469 RGD:2289950 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G ENO2 enolase 2 ISO RGD PMID:18156975 RGD:2293737 NCBI chr27:38,120,404...38,128,543
Ensembl chr27:38,119,413...38,129,182
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:16962163 RGD:2289950 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:16962163 RGD:2289950 NCBI chr10:406,856...424,746
Ensembl chr10:406,633...424,264
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:16962163 RGD:2289950 NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426
JBrowse link
G ESR1 estrogen receptor 1 severity ISO protein:increased phosphorylation RGD PMID:14559803 RGD:4105451 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO DNA:mutations:exons,intron, splice site:varied mutations in different patients, mutations are somatic but identical germline mutations are associated with craniosynostosis and skeletal dysplasia syndromes
ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation
RGD
ClinVar
PMID:7719344 PMID:8651276 PMID:9462761 PMID:9719378 PMID:10851026 More... RGD:2289862 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 disease_progression ISO RGD PMID:17952116 RGD:2301465 NCBI chr16:1,021,855...1,027,604
Ensembl chr16:1,021,972...1,026,392
JBrowse link
G INHA inhibin subunit alpha ISO protein:decreased expression:tumor:significantly higher in normal compared to malignant tissue RGD PMID:17143484 RGD:2290368 NCBI chr37:26,080,465...26,083,570
Ensembl chr37:26,080,510...26,083,391
JBrowse link
G INHBA inhibin subunit beta A ISO protein:decreased expression:endometrium RGD PMID:16423381 RGD:2301688 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794
JBrowse link
G KDR kinase insert domain receptor severity ISO protein:increased expression, increased phosphorylation:tumor:pKDR expression associated with poor overall survival (P=0.009) RGD PMID:16557278 RGD:2291929 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO associated with Ovarian Neoplasms RGD PMID:19542870 RGD:2314910 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO associated with Endometrial Neoplasms RGD PMID:15218296 RGD:2314922 NCBI chr 3:12,668,994...12,766,712
Ensembl chr 3:12,681,577...12,767,183
JBrowse link
G LOC611363 mesothelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14576474 NCBI chr 6:39,827,985...39,834,945 JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:24917306 RGD:13441559 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:24917306 RGD:13441559 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G NKX2-1 NK2 homeobox 1 ISO DNA:hypermethylation RGD PMID:17504987 RGD:2290483
G PDGFRA platelet derived growth factor receptor alpha ISO protein:decreased expression:ovary RGD PMID:15791568 RGD:2298578 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO protein:increased expression:ovary RGD PMID:15791568 RGD:2298578 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283
JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 ISO ClinVar Annotator: match by term: Endometrial Endometrioid Adenocarcinoma, Variant with Squamous Differentiation ClinVar PMID:21984976 NCBI chr20:44,826,037...44,838,449
Ensembl chr20:44,826,339...44,836,558
JBrowse link
G PTEN phosphatase and tensin homolog ISO DNA:loss of heterozygosity, mutations:multiple (human)
DNA:mutations: :multiple
RGD PMID:11156411 PMID:17418409 RGD:12802357 RGD:2289817 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:16633066 RGD:1581360 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISO associated with Ovarian Neoplasms;protein:increased expression:ovary RGD PMID:16439987 RGD:2315091 NCBI chr 5:4,652,493...4,666,728
Ensembl chr 5:4,651,863...4,691,069
JBrowse link
G WIF1 WNT inhibitory factor 1 ISO mRNA:increased expression:ovary RGD PMID:16436637 RGD:2298535 NCBI chr10:7,659,277...7,726,175
Ensembl chr10:7,659,491...7,726,859
JBrowse link
familiar ovarian carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAD51C RAD51 paralog C ISO ClinVar Annotator: match by term: Familial ovarian carcinoma ClinVar PMID:33832919 NCBI chr 9:33,289,675...33,347,411
Ensembl chr 9:33,289,742...33,326,405
JBrowse link
granulosa cell tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMH anti-Mullerian hormone disease_progression ISO RGD PMID:19359032 RGD:2315639 NCBI chr20:56,785,960...56,788,815 JBrowse link
G BMP4 bone morphogenetic protein 4 ISO mRNA:increased expression:ovary RGD PMID:16488995 RGD:1643593 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G CCND2 cyclin D2 ISO mRNA:increased expression:ovary RGD PMID:11994539 RGD:2289157 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO RGD PMID:12203782 RGD:2296066 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CMKLR1 chemerin chemokine-like receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29653259 NCBI chr26:18,487,700...18,539,678
Ensembl chr26:18,532,479...18,533,576
JBrowse link
G CTNNB1 catenin beta 1 ISO RGD PMID:16488995 RGD:1643593 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G FANCF FA complementation group F disease_progression
susceptibility
ISO DNA:hypermethylation:promoter RGD PMID:15574200 PMID:21915857 RGD:11049141 RGD:2298508 NCBI chr21:44,253,308...44,256,221
Ensembl chr21:44,255,134...44,256,618
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO DNA:hypermethylation:promoter, ovary RGD PMID:15574200 RGD:2298508 NCBI chr20:29,735,380...31,113,859
Ensembl chr20:30,356,572...31,113,859
JBrowse link
G FSHR follicle stimulating hormone receptor ISO mRNA:increased expression:tumor:significantly higher vs epithelial tumors or normal ovary (p<0.01) RGD PMID:11994539 RGD:2289157 NCBI chr10:50,765,591...50,938,643
Ensembl chr10:50,770,995...50,938,474
JBrowse link
G GNAI2 G protein subunit alpha i2 ISO ClinVar Annotator: match by term: Granulosa cell tumor, somatic ClinVar PMID:2116665 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO mRNA:decreased expression:ovary RGD PMID:18028988 RGD:2302173 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G LEPR leptin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28861689 NCBI chr 5:44,684,118...44,775,626
Ensembl chr 5:44,688,109...44,775,636
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO mRNA:decreased expression:tumor:significantly lower vs normal ovary (p<0.05) RGD PMID:11994539 PMID:15967102 RGD:2289157 RGD:2302176 NCBI chr10:50,540,706...50,594,336
Ensembl chr10:50,541,960...50,598,036
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase ISO DNA:hypermethylation:promoter (human) RGD PMID:14970867 RGD:2317693 NCBI chr28:38,204,611...38,427,482
Ensembl chr28:38,204,610...38,427,380
JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta ISO mRNA:increased expression:tumor:significantly higher vs epithelial tumors or normal ovary (p<0.01) RGD PMID:11994539 RGD:2289157 NCBI chr18:13,375,216...13,467,811
Ensembl chr18:13,376,425...13,468,038
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO mRNA:increased expression:tumor:significantly higher vs epithelial tumors or normal ovary (p<0.01) RGD PMID:11994539 RGD:2289157 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G RARRES2 retinoic acid receptor responder 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29653259 NCBI chr16:14,671,345...14,675,000
Ensembl chr16:14,671,130...14,674,926
JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO mRNA:decreased expression:tumor:significantly lower vs normal ovary (p<0.01) RGD PMID:11994539 RGD:2289157 NCBI chr 1:27,086,431...27,196,601
Ensembl chr 1:27,087,361...27,196,521
JBrowse link
G SMAD1 SMAD family member 1 ISO RGD PMID:17967875 RGD:2299978 NCBI chr15:44,093,491...44,171,177
Ensembl chr15:44,095,497...44,170,098
JBrowse link
G SMAD5 SMAD family member 5 ISO RGD PMID:17967875 RGD:2299978 NCBI chr11:24,027,603...24,082,673
Ensembl chr11:24,028,126...24,078,169
JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:ovary RGD PMID:16439987 RGD:2315091 NCBI chr 5:4,652,493...4,666,728
Ensembl chr 5:4,651,863...4,691,069
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:19524286 RGD:2315463 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
G WIF1 WNT inhibitory factor 1 ISO mRNA:increased expression:ovary RGD PMID:16488995 RGD:1643593 NCBI chr10:7,659,277...7,726,175
Ensembl chr10:7,659,491...7,726,859
JBrowse link
Granulosa Cell Tumor of the Ovary term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAI2 G protein subunit alpha i2 ISO ClinVar Annotator: match by term: Granulosa cell tumor of the ovary ClinVar PMID:2116665 NCBI chr20:39,075,085...39,094,697
Ensembl chr20:39,075,085...39,094,697
JBrowse link
hereditary breast ovarian cancer syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1CF APOBEC1 complementation factor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr26:37,027,165...37,109,842
Ensembl chr26:37,027,275...37,102,888
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674
JBrowse link
G ABRAXAS1 abraxas 1, BRCA1 A complex subunit ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 PMID:32566746 NCBI chr32:7,298,789...7,316,665
Ensembl chr32:7,298,790...7,317,001
JBrowse link
G ACACA acetyl-CoA carboxylase alpha ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2 ClinVar PMID:25741868 NCBI chr 9:36,904,204...37,188,096
Ensembl chr 9:36,905,293...37,187,892
JBrowse link
G ARL4D ADP ribosylation factor like GTPase 4D ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:19894111 PMID:23996866 PMID:24686251 PMID:28492532 NCBI chr 9:19,832,608...19,834,593
Ensembl chr 9:19,833,192...19,833,797
JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar PMID:3338800 PMID:8808599 PMID:9043869 PMID:9443866 PMID:9463314 More... NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G BARD1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar PMID:12832489 PMID:15855157 PMID:16199547 PMID:17550235 PMID:17848578 More... NCBI chr37:21,946,770...22,024,672
Ensembl chr37:21,948,456...22,024,867
JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476
JBrowse link
G BCL2L1 BCL2 like 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr24:21,145,214...21,209,425
Ensembl chr24:21,145,215...21,196,355
JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr17:25,618,262...25,847,920
Ensembl chr17:25,617,892...25,847,202
JBrowse link
G BLM BLM RecQ like helicase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4
ClinVar PMID:7585968 PMID:17407155 PMID:23129629 PMID:23292937 PMID:24728327 More... NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO OMIM NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO OMIM NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815
JBrowse link
G BRIP1 BRCA1 interacting helicase 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
ClinVar PMID:16116423 PMID:16116424 PMID:17033622 PMID:18483852 PMID:18628483 More... NCBI chr 9:34,804,285...34,984,640
Ensembl chr 9:34,806,535...34,983,788
JBrowse link
G C1H9orf3 aminopeptidase O (putative) ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 PMID:32566746 NCBI chr 1:71,770,687...72,009,374
Ensembl chr 1:71,677,068...72,009,395
JBrowse link
G C5H11orf65 chromosome 5 C11orf65 homolog ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:3338800 PMID:8808599 PMID:9043869 PMID:9443866 PMID:9463314 More... NCBI chr 5:24,106,696...24,166,686
Ensembl chr 5:24,121,409...24,166,291
JBrowse link
G CCNG1 cyclin G1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 4:47,800,697...47,808,259
Ensembl chr 4:47,801,575...47,808,211
JBrowse link
G CDH1 cadherin 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar PMID:12216071 PMID:12944922 PMID:14500541 PMID:16112667 PMID:16924464 More... NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G CDK20 cyclin dependent kinase 20 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 1:97,623,126...97,662,668
Ensembl chr 1:97,622,998...97,662,662
JBrowse link
G CHD1L chromodomain helicase DNA binding protein 1 like ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr17:57,725,823...57,806,065
Ensembl chr17:57,725,640...57,806,048
JBrowse link
G CHEK2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 PMID:11967536 More... NCBI chr26:22,052,256...22,145,675
Ensembl chr26:21,427,961...22,240,624
JBrowse link
G COL2A1 collagen type II alpha 1 chain ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr27:6,756,994...6,787,733
Ensembl chr27:6,756,994...6,787,733
JBrowse link
G CSMD3 CUB and Sushi multiple domains 3 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr13:12,401,118...13,570,464
Ensembl chr13:12,401,565...13,569,798
JBrowse link
G CTNNA1 catenin alpha 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr11:26,273,322...26,459,497
Ensembl chr11:26,143,013...26,459,091
JBrowse link
G CTNNA2 catenin alpha 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr17:43,472,346...44,504,881
Ensembl chr17:43,472,923...44,557,766
JBrowse link
G DHX8 DEAH-box helicase 8 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:19894111 PMID:23996866 PMID:24686251 PMID:28492532 NCBI chr 9:19,734,356...19,766,212
Ensembl chr 9:19,729,816...19,766,555
JBrowse link
G DMBT1 deleted in malignant brain tumors 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr28:32,198,250...32,286,517
Ensembl chr28:32,219,448...32,286,532
JBrowse link
G DROSHA drosha ribonuclease III ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868
G EED embryonic ectoderm development ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr21:13,260,062...13,289,511
Ensembl chr21:13,260,002...13,289,337
JBrowse link
G EFCAB10 EF-hand calcium binding domain 10 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25050558 PMID:25741868 PMID:28492532 PMID:32566746 NCBI chr18:14,833,401...14,844,081
Ensembl chr18:14,833,472...14,845,956
JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G ENO2 enolase 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr27:38,120,404...38,128,543
Ensembl chr27:38,119,413...38,129,182
JBrowse link
G EP300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396
JBrowse link
G EPCAM epithelial cell adhesion molecule ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:25741868 PMID:32566746 NCBI chr10:49,446,165...49,498,690
Ensembl chr10:49,485,746...49,498,475
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr28:1,358,383...1,432,276
Ensembl chr28:1,361,107...1,427,162
JBrowse link
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:47,502,777...47,559,012
Ensembl chr 2:47,503,762...47,558,889
JBrowse link
G ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1 ClinVar PMID:25741868 PMID:28492532 NCBI chr25:29,785,641...29,812,536
Ensembl chr25:29,787,132...29,811,112
JBrowse link
G ETV4 ETS variant transcription factor 4 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:19894111 PMID:23996866 PMID:24686251 PMID:28492532 NCBI chr 9:19,715,259...19,731,085
Ensembl chr 9:19,715,535...19,730,456
JBrowse link
G EXO1 exonuclease 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 7:33,237,124...33,268,835
Ensembl chr 7:33,237,593...33,268,254
JBrowse link
G EYA2 EYA transcriptional coactivator and phosphatase 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr24:34,126,086...34,308,412
Ensembl chr24:34,082,197...34,308,423
JBrowse link
G FAN1 FANCD2 and FANCI associated nuclease 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:38,013,744...38,053,096
Ensembl chr 3:38,013,739...38,052,202
JBrowse link
G FANCC FA complementation group C ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 PMID:32566746 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506
JBrowse link
G FANCE FA complementation group E ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr12:4,587,053...4,600,946
Ensembl chr12:4,587,041...4,600,405
JBrowse link
G FANCM FA complementation group M ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 PMID:32566746 NCBI chr 8:22,561,862...22,625,077
Ensembl chr 8:22,562,147...22,623,994
JBrowse link
G FEN1 flap structure-specific endonuclease 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr18:54,680,627...54,686,502
Ensembl chr18:54,681,760...54,682,902
JBrowse link
G FLCN folliculin ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 5:42,176,093...42,195,718
Ensembl chr 5:42,176,291...42,195,711
JBrowse link
G FLNA filamin A ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr  X:122,058,303...122,083,467
Ensembl chr  X:122,061,455...122,083,203
JBrowse link
G FNDC8 fibronectin type III domain containing 8 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4
ClinVar NCBI chr 9:38,232,116...38,240,791
Ensembl chr 9:38,232,117...38,240,791
JBrowse link
G FOXD1 forkhead box D1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868
G GPHN gephyrin ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 8:40,585,625...41,204,007
Ensembl chr 8:40,585,883...41,203,245
JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 2:59,388,492...59,400,028
Ensembl chr 2:59,388,494...59,400,003
JBrowse link
G ID3 inhibitor of DNA binding 3, HLH protein ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 2:75,880,659...75,881,786
Ensembl chr 2:75,880,657...75,882,010
JBrowse link
G INSL6 insulin like 6 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 1:93,457,854...93,474,777
Ensembl chr 1:93,459,945...93,474,793
JBrowse link
G JAK2 Janus kinase 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4 ClinVar PMID:25741868 PMID:28492532 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369
JBrowse link
G KRT19 keratin 19 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 9:21,240,778...21,245,039 JBrowse link
G LASP1 LIM and SH3 protein 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 9:23,345,226...23,397,058
Ensembl chr 9:23,347,881...23,396,945
JBrowse link
G LCP1 lymphocyte cytosolic protein 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr22:4,955,453...5,059,654
Ensembl chr22:4,992,347...5,059,636
JBrowse link
G LEPROTL1 leptin receptor overlapping transcript like 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr16:34,176,810...34,195,552
Ensembl chr16:34,154,253...34,189,127
JBrowse link
G LIFR LIF receptor subunit alpha ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 4:70,328,963...70,376,127
Ensembl chr 4:70,267,514...70,376,127
JBrowse link
G LRP12 LDL receptor related protein 12 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr13:5,670,932...5,754,076
Ensembl chr13:5,674,649...5,744,740
JBrowse link
G MAFG MAF bZIP transcription factor G ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 9:368,102...373,825
Ensembl chr 9:372,216...372,797
JBrowse link
G MED28 mediator complex subunit 28 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 3:62,887,095...62,895,588
Ensembl chr 3:62,890,515...62,895,562
JBrowse link
G MELK maternal embryonic leucine zipper kinase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr11:52,970,699...53,067,169
Ensembl chr11:52,977,260...53,067,172
JBrowse link
G MITF melanocyte inducing transcription factor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr20:21,772,147...21,873,545
Ensembl chr20:21,612,927...21,870,578
JBrowse link
G MLH1 mutL homolog 1 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:1756143 PMID:7757073 PMID:8581513 PMID:8797773 PMID:8872463 More... NCBI chr23:6,889,108...6,938,117
Ensembl chr23:6,889,135...6,938,116
JBrowse link
G MME membrane metalloendopeptidase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr23:48,966,222...49,059,919
Ensembl chr23:48,971,066...49,059,919
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:9845372 PMID:11196167 PMID:23912341 PMID:24093751 PMID:24894818 More... NCBI chr21:6,448,909...6,528,185
Ensembl chr21:6,449,822...6,527,119
JBrowse link
G MSH2 mutS homolog 2 ISO ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar PMID:9559627 PMID:10024676 PMID:10080150 PMID:10469597 PMID:10777691 More... NCBI chr10:49,517,448...49,594,001
Ensembl chr10:49,517,369...49,594,210
JBrowse link
G MSH6 mutS homolog 6 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar PMID:10675480 PMID:18269114 PMID:23047549 PMID:23621914 PMID:24033266 More... NCBI chr10:49,825,330...49,838,036
Ensembl chr10:49,803,898...49,838,028
JBrowse link
G MTMR10 myotubularin related protein 10 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 3:37,958,771...38,012,893
Ensembl chr 3:37,960,004...38,011,344
JBrowse link
G MUTYH mutY DNA glycosylase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr15:15,018,345...15,026,539
Ensembl chr15:14,906,543...15,026,539
JBrowse link
G MYO5A myosin VA ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr30:17,990,521...18,122,160
Ensembl chr30:17,888,419...18,213,061
JBrowse link
G NBN nibrin ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:9536098 PMID:9590180 PMID:9620777 PMID:10398434 PMID:10852373 More... NCBI chr29:35,416,093...35,477,569
Ensembl chr29:35,416,093...35,477,563
JBrowse link
G NBR1 NBR1 autophagy cargo receptor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:19894111 PMID:23996866 PMID:24686251 PMID:28492532 NCBI chr 9:19,926,885...19,959,552
Ensembl chr 9:19,915,973...19,958,789
JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 5:19,895,587...20,192,334
Ensembl chr 5:19,895,613...20,191,995
JBrowse link
G NEK3 NIMA related kinase 3 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr25:118,558...130,901 JBrowse link
G NEMF nuclear export mediator factor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 8:26,364,664...26,411,475
Ensembl chr 8:26,364,838...26,411,424
JBrowse link
G NF1 neurofibromin 1 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:9691142 PMID:10336779 PMID:11857752 PMID:12807981 PMID:15146469 More... NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382
JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr28:14,902,212...14,910,437
Ensembl chr28:14,902,706...14,910,395
JBrowse link
G NOTCH2 notch receptor 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 1:114,009,573...114,052,100
Ensembl chr 1:114,009,711...114,018,191
JBrowse link
G PALB2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4
ClinVar PMID:16199547 PMID:16793542 PMID:17200668 PMID:17200671 PMID:17420451 More... NCBI chr 6:22,209,711...22,237,798
Ensembl chr 6:22,209,384...22,237,745
JBrowse link
G PAX7 paired box 7 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 2:79,813,835...79,952,490
Ensembl chr 2:79,815,748...79,915,003
JBrowse link
G PCSK7 proprotein convertase subtilisin/kexin type 7 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2 ClinVar PMID:25741868 NCBI chr 5:16,367,737...16,389,991
Ensembl chr 5:16,367,116...16,390,006
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746
JBrowse link
G PLCG1 phospholipase C gamma 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714
JBrowse link
G PLK2 polo like kinase 2 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2 ClinVar PMID:25741868 NCBI chr 2:45,359,865...45,365,496
Ensembl chr 2:45,360,374...45,367,441
JBrowse link
G PMS1 PMS1 homolog 1, mismatch repair system component ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:24728327 PMID:25741868 NCBI chr37:502,752...609,640
Ensembl chr37:502,747...790,904
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar PMID:14756672 PMID:15521988 PMID:22703879 PMID:24728327 PMID:25741868 More... NCBI chr 6:11,411,062...11,438,767
Ensembl chr 6:11,349,453...11,438,940
JBrowse link
G POLQ DNA polymerase theta ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr33:24,713,174...24,837,113
Ensembl chr33:24,714,086...24,837,402
JBrowse link
G PTCH1 patched 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662
JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4
ClinVar PMID:10076877 PMID:10400993 PMID:12938083 PMID:14566704 PMID:17942903 More... NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176
JBrowse link
G PTPRK protein tyrosine phosphatase receptor type K ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 1:66,596,659...67,022,631
Ensembl chr 1:66,597,563...67,124,540
JBrowse link
G PUM1 pumilio RNA binding family member 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 2:69,907,655...70,044,055
Ensembl chr 2:69,907,735...70,042,680
JBrowse link
G PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:32566746 NCBI chr27:26,234,503...26,257,328
Ensembl chr27:26,234,777...26,257,528
JBrowse link
G RAD50 RAD50 double strand break repair protein ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar PMID:16385572 PMID:18281469 PMID:19409520 PMID:23555315 PMID:24240112 More... NCBI chr11:20,836,863...20,928,930
Ensembl chr11:20,836,879...20,928,819
JBrowse link
G RAD51B RAD51 paralog B ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:26898890 PMID:32566746 NCBI chr 8:41,779,435...42,357,362
Ensembl chr 8:41,778,714...42,357,298
JBrowse link
G RAD51C RAD51 paralog C susceptibility ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Breast and Ovarian Cancer Susceptibility
ClinVar Annotator: match by term: BREAST CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:9536098 PMID:12966089 PMID:15170666 PMID:16199547 PMID:17576681 More... NCBI chr 9:33,289,675...33,347,411
Ensembl chr 9:33,289,742...33,326,405
JBrowse link
G RAD51D RAD51 paralog D susceptibility ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 4
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: BREAST CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
ClinVar Annotator: match by term: BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
ClinVar Annotator: match by term: Breast and Ovarian Cancer Susceptibility
ClinVar Annotator: match by term: BREAST CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:9536098 PMID:10749867 PMID:14704354 PMID:15170666 PMID:16199547 More... NCBI chr 9:38,242,178...38,259,788
Ensembl chr 9:38,222,051...38,365,621
JBrowse link
G RAD54L RAD54 like ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr15:14,111,168...14,139,819
Ensembl chr15:14,111,157...14,139,301
JBrowse link
G RALGDS ral guanine nucleotide dissociation stimulator ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 9:51,287,252...51,329,997 JBrowse link
G RECQL RecQ like helicase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:25945795 PMID:27125668 PMID:28492532 PMID:32566746 NCBI chr27:25,590,326...25,636,304
Ensembl chr27:25,590,831...25,636,685
JBrowse link
G RFC1 replication factor C subunit 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 3:73,062,292...73,136,576
Ensembl chr 3:73,062,329...73,135,096
JBrowse link
G RINT1 RAD50 interactor 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25050558 PMID:25741868 PMID:28492532 PMID:32566746 NCBI chr18:14,843,820...14,877,334
Ensembl chr18:14,843,829...14,877,607
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr35:3,367,796...3,407,631
Ensembl chr35:3,263,226...3,405,883
JBrowse link
G RND2 Rho family GTPase 2 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1 ClinVar NCBI chr 9:20,037,469...20,041,044
Ensembl chr 9:20,037,718...20,041,631
JBrowse link
G RPN1 ribophorin I ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr20:2,611,316...2,640,047
Ensembl chr20:2,611,551...2,639,983
JBrowse link
G SAV1 salvador family WW domain containing protein 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 8:27,034,606...27,061,926
Ensembl chr 8:27,022,628...27,062,611
JBrowse link
G SLC34A2 solute carrier family 34 member 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 3:84,686,505...84,717,579
Ensembl chr 3:84,686,425...84,742,038
JBrowse link
G SMAD7 SMAD family member 7 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749
JBrowse link
G SP100 SP100 nuclear antigen ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr25:42,538,428...42,635,825
Ensembl chr25:42,538,571...42,635,649
JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar PMID:10676634 PMID:11430832 PMID:17711506 PMID:18594528 PMID:19892943 More... NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118
JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 3:62,368,641...62,380,898
Ensembl chr 3:62,368,642...62,381,024
JBrowse link
G TDG thymine DNA glycosylase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr15:42,493,593...42,516,868
Ensembl chr15:42,493,737...42,515,448
JBrowse link
G TERT telomerase reverse transcriptase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951
JBrowse link
G TES testin LIM domain protein ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr14:55,217,768...55,240,668
Ensembl chr14:55,177,375...55,240,668
JBrowse link
G TEX14 testis expressed 14, intercellular bridge forming factor ISO ClinVar Annotator: match by term: BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3 ClinVar NCBI chr 9:33,174,813...33,289,202
Ensembl chr 9:33,174,814...33,262,870
JBrowse link
G TFRC transferrin receptor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr33:29,206,024...29,237,221
Ensembl chr33:29,208,609...29,238,242
JBrowse link
G TG thyroglobulin ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr13:29,350,726...29,597,908
Ensembl chr13:29,350,688...29,598,040
JBrowse link
G TLX3 T cell leukemia homeobox 3 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 4:40,816,351...40,818,582
Ensembl chr 4:40,816,467...40,818,723
JBrowse link
G TMEM106A transmembrane protein 106A ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:19894111 PMID:23996866 PMID:24686251 PMID:28492532 NCBI chr 9:19,917,591...19,926,578
Ensembl chr 9:19,915,973...19,958,789
JBrowse link
G TNC tenascin C ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr11:69,077,532...69,169,673
Ensembl chr11:69,077,535...69,170,281
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Breast and/or ovarian cancer
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Breast-ovarian cancer, familial 1
ClinVar PMID:1467311 PMID:1565143 PMID:1631137 PMID:1978757 PMID:2259385 More... NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G TPM4 tropomyosin 4 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr20:46,354,808...46,376,489
Ensembl chr20:46,355,736...46,376,425
JBrowse link
G TSHR thyroid stimulating hormone receptor ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 8:53,327,280...53,482,898
Ensembl chr 8:53,326,655...53,482,898
JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr30:8,571,230...8,602,655
Ensembl chr30:8,571,475...8,598,721
JBrowse link
G UFL1 UFM1 specific ligase 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr12:54,988,200...55,023,414
Ensembl chr12:54,988,264...55,021,626
JBrowse link
G UNG uracil DNA glycosylase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr26:17,900,354...17,911,126
Ensembl chr26:17,901,357...17,911,288
JBrowse link
G VRK1 VRK serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2 ClinVar PMID:25741868 PMID:28492532 NCBI chr 8:65,444,404...65,551,348
Ensembl chr 8:65,443,949...65,551,151
JBrowse link
G VTI1A vesicle transport through interaction with t-SNAREs 1A ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr28:23,496,553...23,854,609
Ensembl chr28:23,496,593...23,842,369
JBrowse link
G WDR11 WD repeat domain 11 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr28:30,769,223...30,828,628
Ensembl chr28:30,769,219...30,828,049
JBrowse link
G WIF1 WNT inhibitory factor 1 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr10:7,659,277...7,726,175
Ensembl chr10:7,659,491...7,726,859
JBrowse link
G WWOX WW domain containing oxidoreductase ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 NCBI chr 5:72,298,254...73,243,667
Ensembl chr 5:72,299,157...73,261,406
JBrowse link
G XRCC2 X-ray repair cross complementing 2 ISO ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome ClinVar PMID:25741868 PMID:32566746 NCBI chr16:16,402,821...16,429,095
Ensembl chr16:16,402,933...16,429,037
JBrowse link
G ZAR1L zygote arrest 1 like ISO ClinVar Annotator: match by term: Breast-ovarian cancer, familial 2
ClinVar Annotator: match by term: Hereditary breast and ovarian cancer syndrome
ClinVar PMID:28492532 PMID:31843900 NCBI chr25:7,799,130...7,807,653
Ensembl chr25:7,799,615...7,856,230
JBrowse link
Krukenberg carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD44 CD44 molecule ISO protein:increased expression:ovary RGD PMID:16124061 RGD:2289359 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107
JBrowse link
malignant ovarian germ cell neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBL Cbl proto-oncogene ISO ClinVar Annotator: match by term: Malignant germ cell tumor of ovary ClinVar PMID:19571318 PMID:20694012 PMID:20955399 PMID:21901340 PMID:24033266 More... NCBI chr 5:14,600,409...14,676,974
Ensembl chr 5:14,607,013...14,676,956
JBrowse link
G FANCM FA complementation group M ISO ClinVar Annotator: match by term: Malignant germ cell tumor of ovary ClinVar PMID:17289582 PMID:18174376 PMID:19379763 PMID:23932590 PMID:24003026 More... NCBI chr 8:22,561,862...22,625,077
Ensembl chr 8:22,562,147...22,623,994
JBrowse link
ovarian cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 disease_progression ISO RGD PMID:19603017 RGD:2315556 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G AKT1 AKT serine/threonine kinase 1 susceptibility ISO DNA:point mutation:cds:p.E17K (human) OMIM
RGD
PMID:17611497 RGD:1643334 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G ANGPT1 angiopoietin 1 ISO mRNA:decreased expression:ovary RGD PMID:12138242 RGD:2293864 NCBI chr13:8,068,920...8,312,090
Ensembl chr13:8,048,205...8,311,618
JBrowse link
G ANXA7 annexin A7 ISO protein:decreased expression:ovary RGD PMID:17708571 RGD:2292654 NCBI chr 4:23,933,959...23,961,968
Ensembl chr 4:23,934,234...23,961,880
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO RGD PMID:17974506 PMID:19787261 RGD:2315656 RGD:2315663 NCBI chr15:17,786,808...17,789,422
Ensembl chr15:17,786,357...17,789,422
JBrowse link
G APOB apolipoprotein B severity ISO RGD PMID:9023386 RGD:11354936 NCBI chr17:15,877,937...15,916,032
Ensembl chr17:15,878,244...15,915,135
JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Familial ovarian cancer ClinVar PMID:8659541 PMID:9463314 PMID:9872980 PMID:10330348 PMID:11756185 More... NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G AURKA aurora kinase A susceptibility ISO DNA:SNP:cds:p.F31I RGD PMID:15466974 RGD:2293884 NCBI chr24:41,585,483...41,604,875
Ensembl chr24:41,585,518...41,604,791
JBrowse link
G BARD1 BRCA1 associated RING domain 1 ISO DNA, mRNA, protein:missense mutation, alternative form, increased expression, altered localization:p.Q406R, ovary (human)
ClinVar Annotator: match by term: Familial ovarian cancer
RGD
ClinVar
PMID:16152612 PMID:25741868 PMID:26350354 PMID:26467025 PMID:27498913 More... RGD:2315727 NCBI chr37:21,946,770...22,024,672
Ensembl chr37:21,948,456...22,024,867
JBrowse link
G BRCA1 BRCA1 DNA repair associated susceptibility ISO DNA:insertion: :5382insC
ClinVar Annotator: match by term: Ovarian cancer
mRNA, protein:splice variant
RGD
ClinVar
PMID:7837387 PMID:7894493 PMID:8644702 PMID:8807330 PMID:9150149 More... RGD:126925963 RGD:2293152 RGD:734656 NCBI chr 9:19,958,941...20,025,494
Ensembl chr 9:19,958,391...20,025,494
JBrowse link
G BRCA2 BRCA2 DNA repair associated no_association
disease_progression
ISO DNA:SNP:cds:p.N372H (rs144848)(human)
ClinVar Annotator: match by term: Ovarian cancer
DNA:deletion: :6174delT
DNA:deletion:cds:p.R2744-G2748del(human)
RGD
ClinVar
PMID:11179017 PMID:14757868 PMID:14973102 PMID:15070707 PMID:15145354 More... RGD:2289046 RGD:9068461 RGD:9068468 NCBI chr25:7,734,450...7,797,851
Ensembl chr25:7,734,453...7,797,815
JBrowse link
G BRIP1 BRCA1 interacting helicase 1 ISO ClinVar Annotator: match by term: Ovarian Cancers
ClinVar Annotator: match by term: Familial ovarian cancer
ClinVar PMID:17033622 PMID:21279724 PMID:23555315 PMID:24728327 PMID:25186627 More... NCBI chr 9:34,804,285...34,984,640
Ensembl chr 9:34,806,535...34,983,788
JBrowse link
G C1H9orf3 aminopeptidase O (putative) ISO ClinVar Annotator: match by term: Familial ovarian cancer ClinVar PMID:28492532 NCBI chr 1:71,770,687...72,009,374
Ensembl chr 1:71,677,068...72,009,395
JBrowse link
G C5H11orf65 chromosome 5 C11orf65 homolog ISO ClinVar Annotator: match by term: Familial ovarian cancer ClinVar PMID:8659541 PMID:9463314 PMID:9872980 PMID:10330348 PMID:11756185 More... NCBI chr 5:24,106,696...24,166,686
Ensembl chr 5:24,121,409...24,166,291
JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 disease_progression ISO RGD PMID:26175272 RGD:18337279
G CCN2 cellular communication network factor 2 ISO mRNA:decreased expression:ovarian carcinoma (human) RGD PMID:19382180 RGD:2314512 NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145
JBrowse link
G CD163 CD163 molecule ameliorates ISO RGD PMID:31951251 RGD:149735527 NCBI chr27:37,669,757...37,700,746
Ensembl chr27:37,669,827...37,753,106
JBrowse link
G CD274 CD274 molecule treatment ISO associated with ovarian cancer RGD PMID:23340297 PMID:28424330 RGD:41410791 RGD:41410797 NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522
JBrowse link
G CD59 CD59 molecule ISO RGD PMID:15726105 PMID:19254481 RGD:2306066 RGD:2326189 NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329
JBrowse link
G CD82 CD82 molecule disease_progression ISO protein:altered localization, decreased expression:ovary RGD PMID:12079303 RGD:2289405 NCBI chr18:44,658,414...44,707,897
Ensembl chr18:44,659,180...44,706,768
JBrowse link
G CD9 CD9 molecule disease_progression ISO protein:decreased expression, altered localization:ovary RGD PMID:12079303 RGD:2289405 NCBI chr27:38,742,539...38,754,984
Ensembl chr27:38,742,963...38,774,576
JBrowse link
G CDH1 cadherin 1 ISO OMIM NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G CDH13 cadherin 13 ISO DNA:hypermethylation:promoter RGD PMID:10493953 RGD:2298987 NCBI chr 5:68,491,156...69,586,119
Ensembl chr 5:68,492,022...69,489,255
JBrowse link
G CHEK2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Familial ovarian cancer ClinVar PMID:17145815 PMID:21153778 PMID:21681852 PMID:21876083 PMID:24713400 More... NCBI chr26:22,052,256...22,145,675
Ensembl chr26:21,427,961...22,240,624
JBrowse link
G CHI3L1 chitinase 3 like 1 severity ISO protein:increased secretion:plasma (human) RGD PMID:12883737 RGD:4892638 NCBI chr 7:25,620...32,954
Ensembl chr 7:26,316...33,427
JBrowse link
G CLDN4 claudin 4 ISO RGD PMID:19555390 RGD:2317583 NCBI chr 6:6,492,706...6,506,750
Ensembl chr 6:6,493,513...6,494,145
JBrowse link
G COMT catechol-O-methyltransferase no_association
susceptibility
ISO DNA:polymorphism:exon:p.V158M
DNA:polymorphism: :p.V158M
mRNA:increased expression:ovary
RGD PMID:11142424 PMID:12036914 PMID:15010821 RGD:2289722 RGD:2289724 RGD:2289725 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO RGD PMID:16391854 RGD:7488899 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964
JBrowse link
G CTNNB1 catenin beta 1 ISO OMIM NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO DNA:SNP::increase in frequency of mutant heterozygote C/T (p=0.001) RGD PMID:18497059 RGD:2301045 NCBI chr30:16,954,020...17,056,728
Ensembl chr30:16,957,215...16,988,353
JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 disease_progression ISO protein:increased expression:ovary RGD PMID:15164121 RGD:2289854 NCBI chr13:10,081,700...10,099,737
Ensembl chr13:10,081,695...10,099,501
JBrowse link
G EFEMP2 EGF containing fibulin extracellular matrix protein 2 exacerbates ISO mRNA, protein:increased expression:ovary (human) RGD PMID:25885889 RGD:42722014 NCBI chr18:51,389,797...51,396,109
Ensembl chr18:51,389,824...51,396,107
JBrowse link
G EGF epidermal growth factor ISO protein:increased expression:serum (human) RGD PMID:22914212 RGD:13673914 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO OMIM NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit disease_progression ISO RGD PMID:21216588 RGD:11252174 NCBI chr 1:110,130,353...110,146,660
Ensembl chr 1:110,130,481...110,146,602
JBrowse link
G ESR1 estrogen receptor 1 ISO associated with Mammary Neoplasms, Experimental;protein:decreased expression:ovary, breast RGD PMID:16891317 RGD:2290042 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21833453 RGD:5147781 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459
JBrowse link
G F7 coagulation factor VII ISO protein:increased expression:ovarian surface epithelium (human) RGD PMID:19904262 RGD:11049516 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024
JBrowse link
G FANCA FA complementation group A ISO DNA:duplication:promoter RGD PMID:15860134 RGD:11344887 NCBI chr 5:63,778,149...63,838,869
Ensembl chr 5:63,778,212...63,838,823
JBrowse link
G FANCC FA complementation group C ISO ClinVar Annotator: match by term: Familial ovarian cancer ClinVar PMID:28492532 NCBI chr 1:71,388,931...71,678,019
Ensembl chr 1:71,487,601...71,678,506
JBrowse link
G FAS Fas cell surface death receptor disease_progression ISO protein:increased expression:blood, peritoneal fluid, T cell RGD PMID:17565840 RGD:2290084 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321
JBrowse link
G FERMT3 FERM domain containing kindlin 3 ISO protein:decreased expression:serum RGD PMID:22818854 RGD:11035257 NCBI chr18:52,833,954...52,851,775
Ensembl chr18:52,834,001...52,851,667
JBrowse link
G FGF1 fibroblast growth factor 1 disease_progression ISO mRNA:increased expression:ovary RGD PMID:14613644 RGD:2290288 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619
JBrowse link
G FGF2 fibroblast growth factor 2 disease_progression ISO mRNA:increased expression:ovary RGD PMID:14613644 RGD:2290288 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151
JBrowse link
G FGF7 fibroblast growth factor 7 ISO protein:increased expression:ovary RGD PMID:11000522 RGD:2289080 NCBI chr30:15,555,016...15,608,230
Ensembl chr30:15,555,266...15,606,521
JBrowse link
G GHRH growth hormone releasing hormone ISO mRNA:increased expression:endometrium
mRNA:increased expression:tumor:expression in 17/22 specimens
RGD PMID:10022420 PMID:11163834 PMID:11710593 RGD:2289974 RGD:2301424 RGD:2301425 NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712
JBrowse link
G GSTP1 glutathione S-transferase pi 1 treatment ISO DNA:polymorphism:cds:p.I105V(human) RGD PMID:19786980 RGD:5688741 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182
JBrowse link
G HDAC3 histone deacetylase 3 ISO protein:increased expression:ovary RGD PMID:17387270 RGD:2306215 NCBI chr 2:36,583,283...36,598,121
Ensembl chr 2:36,583,283...36,597,682
JBrowse link
G HFE homeostatic iron regulator susceptibility ISO DNA:missense mutation:cds:p.H63D (human) RGD PMID:16216474 RGD:8694371 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha disease_progression ISO RGD PMID:19014607 RGD:2306225 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G HMGA2 high mobility group AT-hook 2 ISO RGD PMID:18452175 RGD:5147841 NCBI chr10:8,348,101...8,491,435 JBrowse link
G HTRA2 HtrA serine peptidase 2 ISO mRNA:decreased expression:ovary (human) RGD PMID:18241672 RGD:5688746 NCBI chr17:48,610,408...48,613,399
Ensembl chr17:48,610,408...48,613,399
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:serum: RGD PMID:7686390 RGD:11520780 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914
JBrowse link
G IL10 interleukin 10 ISO protein:increased expression:serum RGD PMID:9166545 RGD:2317660 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G ILK integrin linked kinase severity ISO protein:increased expression:ovary, surface of epithelium (human) RGD PMID:14517840 RGD:13441558 NCBI chr21:29,911,326...29,917,972
Ensembl chr21:29,911,364...29,917,974