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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Periapical Diseases
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Accession:DOID:9002699 term browser browse the term
Definition:Diseases of the PERIAPICAL TISSUE surrounding the root of the tooth, which is distinguished from DENTAL PULP DISEASES inside the TOOTH ROOT.
Synonyms:exact_synonym: Periapical Disease
 primary_id: MESH:D010483;   RDO:0006316
For additional species annotation, visit the Alliance of Genome Resources.


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Periapical Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:23829599 RGD:9491793 NCBI chrNW_004936475:9,443,851...9,454,715 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO RGD PMID:17509411 RGD:10449488 NCBI chrNW_004936492:2,353,840...2,368,573 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b ISO RGD PMID:21793936 RGD:7205516 NCBI chrNW_004936470:27,571,263...27,598,725 JBrowse link
periapical granuloma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:11683586 RGD:6893426 NCBI chrNW_004936596:223,660...224,739 JBrowse link
periapical periodontitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ciita class II major histocompatibility complex transactivator ISO RGD PMID:20478458 RGD:7242892 NCBI chrNW_004936530:9,033,510...9,073,341 JBrowse link
G Il17a interleukin 17A ISO protein:increased expression:Periapical Tissue RGD PMID:19166776 RGD:4832829 NCBI chrNW_004936476:8,621,860...8,625,008 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b treatment ISO Lactobacillus acidophilus RGD PMID:32436602 RGD:42721981 NCBI chrNW_004936470:27,571,263...27,598,725 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12792
    Stomatognathic Diseases 877
      Jaw Diseases 269
        Periapical Diseases 6
          Radicular Cyst 0
          periapical periodontitis + 4
Path 2
Term Annotations click to browse term
  disease 12792
    disease of anatomical entity 12471
      nervous system disease 10342
        sensory system disease 4707
          mouth disease 672
            tooth disease 261
              periodontal disease 100
                Periapical Diseases 6
                  Radicular Cyst 0
                  periapical periodontitis + 4
paths to the root