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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Peritoneal Fibrosis
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Accession:DOID:9002488 term browser browse the term
Definition:Disorder characterized by a wide range of structural changes in PERITONEUM, resulting from fibrogenic or inflammatory processes. Peritoneal fibrosis is a common complication in patients receiving PERITONEAL DIALYSIS and contributes to its gradual decrease in efficiency.
Synonyms:exact_synonym: Encapsulating Peritoneal Scleroses;   Encapsulating Peritoneal Sclerosis;   Peritoneal Fibroses;   Peritoneal Fibrosing Syndrome;   Peritoneal Fibrosing Syndromes;   Peritoneal Scleroses;   Peritoneal Sclerosis
 primary_id: MESH:D056627;   RDO:0007745
 xref: EFO:1001394


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Peritoneal Fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme treatment IMP
ISO		 RGD PMID:15770604 PMID:19270231 RGD:12879430, RGD:12879821 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IDA associated with Diabetic Nephropathies RGD PMID:19759273 RGD:7244162 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:23032084 RGD:14995948 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn2 cellular communication network factor 2 treatment IEP RGD PMID:32585450 RGD:41410783 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Col3a1 collagen type III alpha 1 chain treatment
disease_progression		 IEP RGD PMID:12911538 PMID:12691502 RGD:41410781, RGD:41410779 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP protein:increased expression:peritoneum: RGD PMID:25256793 RGD:9588609 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 treatment IMP RGD PMID:31836774 RGD:32733624 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G F10 coagulation factor X IEP RGD PMID:19458308 RGD:7394780 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F3 coagulation factor III, tissue factor IEP RGD PMID:19458308 RGD:7394780 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G F5 coagulation factor V IEP RGD PMID:19458308 RGD:7394780 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G Fgf10 fibroblast growth factor 10 treatment ISO miR-145 inhibitor
mRNA:decreased expression:peritoneum (mouse)		 RGD PMID:31431501 PMID:31431501 RGD:126928131, RGD:126928131 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Mir21 microRNA 21 IEP RNA:increased expression:peritoneal fluid,tissue RGD PMID:30515805 RGD:40925948 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22101032 RGD:6771356 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO associated with Peritonitis RGD PMID:18458955 RGD:11035266 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Serpine1 serpin family E member 1 ISO protein:increased expression:peritoneal fluid: RGD PMID:25530106 RGD:13208550 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinh1 serpin family H member 1 disease_progression
treatment		 IEP
ISO
IMP		 protein:increased expression:peritoneum (rat) RGD PMID:12691502 PMID:32585450 PMID:15458466 PMID:12911538 RGD:41410779, RGD:41410783, RGD:41410782, RGD:41410781 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 IEP mRNA, protein:decreased expression:peritoneal fluid,tissue RGD PMID:30515805 RGD:40925948 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17199790 PMID:28190234 RGD:14985233 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 treatment IMP RGD PMID:22912904 RGD:7777188 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Xbp1 X-box binding protein 1 treatment IEP RGD PMID:31836774 RGD:32733624 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19141
    disease of anatomical entity 18453
      gastrointestinal system disease 7189
        Peritoneal Diseases 84
          Peritoneal Fibrosis 20
paths to the root