Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:Hyperalgesia
go back to main search page
Accession:DOID:9002211 term browser browse the term
Definition:An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
Synonyms:exact_synonym: Allodynia;   Allodynias, Mechanical;   Allodynias, Tactile;   Allodynias, Thermal;   Hyperalgesia, Primary;   Hyperalgesia, Secondary;   Hyperalgesia, Tactile;   Hyperalgesias;   Hyperalgesias, Mechanical;   Hyperalgesias, Primary;   Hyperalgesias, Secondary;   Hyperalgesias, Tactile;   Hyperalgesias, Thermal;   Hyperalgesic Sensations;   Mechanical Allodynia;   Mechanical Hyperalgesia;   Tactile Allodynia;   Thermal Allodynia;   Thermal Hyperalgesia;   pain hypersensitivity
 primary_id: MESH:D006930;   RDO:0005827
For additional species annotation, visit the Alliance of Genome Resources.


GViewer not supported for chinchilla.
show annotations for term's descendants       view all columns           Sort by:
 
Hyperalgesia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link NW_004955442 9,422,849 9,516,054 RGD:9068941
G Adk adenosine kinase JBrowse link NW_004955437 17,279,541 17,786,140 RGD:9068941
G Adm adrenomedullin JBrowse link NW_004955414 25,951,473 25,953,593 RGD:9068941
G Adora1 adenosine A1 receptor JBrowse link NW_004955406 39,148,811 39,183,577 RGD:9068941
G Adra1a adrenoceptor alpha 1A JBrowse link NW_004955403 49,394,173 49,485,881 RGD:9068941
G Adra2a adrenoceptor alpha 2A JBrowse link NW_004955485 384,405 387,332 RGD:9068941
G Adrb1 adrenoceptor beta 1 JBrowse link NW_004955431 19,025,663 19,027,026 RGD:9068941
G Ager advanced glycosylation end-product specific receptor JBrowse link NW_004955437 645,482 648,607 RGD:9068941
G Agt angiotensinogen JBrowse link NW_004955492 7,863,662 7,874,863 RGD:9068941
G Aif1 allograft inflammatory factor 1 JBrowse link NW_004955437 157,509 158,919 RGD:9068941
G Alox5 arachidonate 5-lipoxygenase JBrowse link NW_004955546 2,495,226 2,550,909 RGD:9068941
G Ano3 anoctamin 3 JBrowse link NW_004955476 5,702,888 6,060,545 RGD:9068941
G Anxa1 annexin A1 JBrowse link NW_004955512 5,686,508 5,703,645 RGD:9068941
G Aqp4 aquaporin 4 JBrowse link NW_004955772 1,160 10,709 RGD:9068941
G Bace1 beta-secretase 1 JBrowse link NW_004955412 18,596,643 18,620,089 RGD:9068941
G Bdkrb1 bradykinin receptor B1 JBrowse link NW_004955438 16,500,219 16,505,394 RGD:9068941
G Bdkrb2 bradykinin receptor B2 JBrowse link NW_004955438 16,514,300 16,537,160 RGD:9068941
G Bdnf brain derived neurotrophic factor JBrowse link NW_004955476 6,773,244 6,822,201 RGD:9068941
G Becn1 beclin 1 JBrowse link NW_004955451 16,616,595 16,625,731 RGD:9068941
G C3 complement C3 JBrowse link NW_004955495 2,796,601 2,824,233 RGD:9068941
G Cacna1b calcium voltage-gated channel subunit alpha1 B JBrowse link NW_004955513 5,654,915 5,823,094 RGD:9068941
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link NW_004955442 16,047,965 16,108,862 RGD:9068941
G Cacna1i calcium voltage-gated channel subunit alpha1 I JBrowse link NW_004955413 25,440,533 25,538,367 RGD:9068941
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link NW_004955410 3,544,398 3,963,582 RGD:9068941
G Camk2a calcium/calmodulin dependent protein kinase II alpha JBrowse link NW_004955415 4,247,307 4,307,402 RGD:9068941
G Capn2 calpain 2 JBrowse link NW_004955520 1,287,829 1,315,318 RGD:9068941
G Cartpt CART prepropeptide JBrowse link NW_004955575 551,991 555,118 RGD:9068941
G Cat catalase JBrowse link NW_004955422 11,783,973 11,826,970 RGD:9068941
G Cck cholecystokinin JBrowse link NW_004955420 28,438,806 28,443,458 RGD:9068941
G Cckbr cholecystokinin B receptor JBrowse link NW_004955414 22,001,351 22,011,275 RGD:9068941
G Ccl5 C-C motif chemokine ligand 5 JBrowse link NW_004955481 10,293,758 10,301,118 RGD:9068941
G Ccr2 C-C motif chemokine receptor 2 JBrowse link NW_004955420 25,641,184 25,664,413 RGD:9068941
G Cfl1 cofilin 1 JBrowse link NW_004955422 19,479,181 19,482,571 RGD:9068941
G Cnr1 cannabinoid receptor 1 JBrowse link NW_004955411 15,052,151 15,077,320 RGD:9068941
G Cnr2 cannabinoid receptor 2 JBrowse link NW_004955452 3,763,742 3,795,069 RGD:9068941
G Comt catechol-O-methyltransferase JBrowse link NW_004955442 18,130,282 18,152,153 RGD:9068941
G Crcp CGRP receptor component JBrowse link NW_004955456 8,431,161 8,479,866 RGD:9068941
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link NW_004955478 10,380,185 10,390,838 RGD:9068941
G Csf3 colony stimulating factor 3 JBrowse link NW_004955451 14,688,181 14,690,126 RGD:9068941
G Csk C-terminal Src kinase JBrowse link NW_004955450 3,127,561 3,144,550 RGD:9068941
G Ctss cathepsin S JBrowse link NW_004955413 99,279 124,793 RGD:9068941
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link NW_004955433 15,023,272 15,034,650 RGD:9068941
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link NW_004955427 24,691,206 24,705,599 RGD:9068941
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link NW_004955546 1,929,269 1,941,690 RGD:9068941
G Cxcl8 C-X-C motif chemokine ligand 8 JBrowse link NW_004955474 247,326 250,355 RGD:9068941
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link NW_004955440 3,456,165 3,460,024 RGD:9068941
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link NW_004955467 9,691,733 9,715,872 RGD:9068941
G Dnmt1 DNA methyltransferase 1 JBrowse link NW_004955495 1,465,529 1,505,379 RGD:9068941
G Drd3 dopamine receptor D3 JBrowse link NW_004955427 14,219,519 14,252,178 RGD:9068941
G Dusp1 dual specificity phosphatase 1 JBrowse link NW_004955408 25,481,294 25,484,381 RGD:9068941
G Dusp6 dual specificity phosphatase 6 JBrowse link NW_004955405 26,662,018 26,666,314 RGD:9068941
G Edn1 endothelin 1 JBrowse link NW_004955465 2,287,906 2,314,945 RGD:9068941
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link NW_004955417 25,308,424 25,384,307 RGD:9068941
G Ep300 E1A binding protein p300 JBrowse link NW_004955413 26,647,553 26,727,875 RGD:9068941
G Epha4 EPH receptor A4 JBrowse link NW_004955453 12,099,800 12,240,199 RGD:9068941
G Ephx2 epoxide hydrolase 2 JBrowse link NW_004955403 49,999,563 50,038,800 RGD:9068941
G Esr1 estrogen receptor 1 JBrowse link NW_004955439 9,588,631 9,953,606 RGD:9068941
G Esr2 estrogen receptor 2 JBrowse link NW_004955466 5,587,003 5,644,765 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link NW_004955422 1,356,675 1,367,788 RGD:9068941
G F2r coagulation factor II thrombin receptor JBrowse link NW_004955425 24,144,905 24,164,498 RGD:9068941
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link NW_004955523 307,181 310,728 RGD:9068941
G Gal galanin and GMAP prepropeptide JBrowse link NW_004955422 17,202,770 17,207,948 RGD:9068941
G Gdnf glial cell derived neurotrophic factor JBrowse link NW_004955426 22,386,613 22,412,324 RGD:9068941
G Gfap glial fibrillary acidic protein JBrowse link NW_004955451 17,695,835 17,703,894 RGD:9068941
G Gfra1 GDNF family receptor alpha 1 JBrowse link NW_004955431 20,859,152 21,070,886 RGD:9068941
G Gja1 gap junction protein alpha 1 JBrowse link NW_004955436 3,612,533 3,618,095 RGD:9068941
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link NW_004955513 5,154,864 5,178,636 RGD:9068941
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link NW_004955442 8,171,114 8,565,187 RGD:9068941
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link NW_004955413 10,358,931 10,780,004 RGD:9068941
G Grk2 G protein-coupled receptor kinase 2 JBrowse link NW_004955422 18,173,438 18,192,357 RGD:9068941
G Grm8 glutamate metabotropic receptor 8 JBrowse link NW_004955479 7,520,537 8,279,942 RGD:9068941
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link NW_004955466 8,000,311 8,022,497 RGD:9068941
G Hmgb1 high mobility group box 1 JBrowse link NW_004955431 15,373,207 15,377,339 RGD:9068941
G Hoxd1 homeobox D1 JBrowse link NW_004955403 20,476,813 20,478,604 RGD:9068941
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link NW_004955431 583,165 646,991 RGD:9068941
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link NW_004955425 2,321,420 2,420,420 RGD:9068941
G Igf1 insulin like growth factor 1 JBrowse link NW_004955405 37,505,830 37,582,152 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il13 interleukin 13 JBrowse link NW_004955408 4,046,406 4,049,795 RGD:9068941
G Il17a interleukin 17A JBrowse link NW_004955411 5,896,435 5,899,911 RGD:9068941
G Il18 interleukin 18 JBrowse link NW_004955412 13,807,361 13,826,007 RGD:9068941
G Il1a interleukin 1 alpha JBrowse link NW_004955470 1,527,710 1,538,418 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Il1r1 interleukin 1 receptor type 1 JBrowse link NW_004955470 7,685,498 7,703,374 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004955470 1,145,022 1,159,413 RGD:9068941
G Il2 interleukin 2 JBrowse link NW_004955428 18,163,010 18,168,157 RGD:9068941
G Il6 interleukin 6 JBrowse link NW_004955410 25,079,835 25,084,390 RGD:9068941
G Il6r interleukin 6 receptor JBrowse link NW_004955545 932,814 979,359 RGD:9068941
G Insr insulin receptor JBrowse link NW_004955563 1,867,400 2,011,845 RGD:9068941
G Itga1 integrin subunit alpha 1 JBrowse link NW_004955446 14,439,571 14,582,236 RGD:9068941
G Itga2 integrin subunit alpha 2 JBrowse link NW_004955446 14,309,516 14,421,991 RGD:9068941
G Itga3 integrin subunit alpha 3 JBrowse link NW_004955451 11,563,120 11,590,119 RGD:9068941
G Itga5 integrin subunit alpha 5 JBrowse link NW_004955458 1,635,554 1,657,609 RGD:9068941
G Itgb1 integrin subunit beta 1 JBrowse link NW_004955462 4,454,809 4,483,227 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:9068941
G Jak3 Janus kinase 3 JBrowse link NW_004955524 3,399,895 3,412,018 RGD:9068941
G Kcnc4 potassium voltage-gated channel subfamily C member 4 JBrowse link NW_004955435 13,728,272 13,750,420 RGD:9068941
G Kcnk2 potassium two pore domain channel subfamily K member 2 JBrowse link NW_004955406 2,793,493 2,975,322 RGD:9068941
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 JBrowse link NW_004955461 6,793,877 7,119,859 RGD:9068941
G Kmo kynurenine 3-monooxygenase JBrowse link NW_004955406 10,496,102 10,527,181 RGD:9068941
G Kng1 kininogen 1 JBrowse link NW_004955420 20,989,197 21,016,084 RGD:9068941
G LOC102012042 cytochrome b-245 heavy chain JBrowse link NW_004955587 781,533 818,149 RGD:9068941
G Map1lc3a microtubule associated protein 1 light chain 3 alpha JBrowse link NW_004955422 26,774,466 26,776,024 RGD:9068941
G Map2k3 mitogen-activated protein kinase kinase 3 JBrowse link NW_004955577 1,225,033 1,249,510 RGD:9068941
G Mapk1 mitogen-activated protein kinase 1 JBrowse link NW_004955442 17,284,232 17,380,026 RGD:9068941
G Mapk3 mitogen-activated protein kinase 3 JBrowse link NW_004955493 6,870,699 6,876,836 RGD:9068941
G Mapk7 mitogen-activated protein kinase 7 JBrowse link NW_004955467 381,801 387,078 RGD:9068941
G Mapk8 mitogen-activated protein kinase 8 JBrowse link NW_004955556 1,593,552 1,705,543 RGD:9068941
G Mapk9 mitogen-activated protein kinase 9 JBrowse link NW_004955408 391,094 430,638 RGD:9068941
G Mc4r melanocortin 4 receptor JBrowse link NW_004955402 44,453,973 44,456,689 RGD:9068941
G Men1 menin 1 JBrowse link NW_004955422 20,356,491 20,363,374 RGD:9068941
G Mfn2 mitofusin 2 JBrowse link NW_004955486 1,937,873 1,962,577 RGD:9068941
G Mpz myelin protein zero JBrowse link NW_004955468 13,041,911 13,047,026 RGD:9068941
G Mtor mechanistic target of rapamycin kinase JBrowse link NW_004955486 2,487,642 2,599,694 RGD:9068941
G Nefh neurofilament heavy JBrowse link NW_004955455 3,735,330 3,744,714 RGD:9068941
G Ngf nerve growth factor JBrowse link NW_004955435 18,581,889 18,633,330 RGD:9068941
G Ngfr nerve growth factor receptor JBrowse link NW_004955451 12,030,303 12,047,305 RGD:9068941
G Nlgn2 neuroligin 2 JBrowse link NW_004955467 9,504,974 9,520,059 RGD:9068941
G Nos1 nitric oxide synthase 1 JBrowse link NW_004955455 13,797,557 13,978,402 RGD:9068941
G Nos2 nitric oxide synthase 2 JBrowse link NW_004955481 5,197,957 5,232,406 RGD:9068941
G Npy neuropeptide Y JBrowse link NW_004955410 26,348,388 26,355,232 RGD:9068941
G Nrg1 neuregulin 1 JBrowse link NW_004955463 8,009,436 9,037,116 RGD:9068941
G Ntf3 neurotrophin 3 JBrowse link NW_004955413 3,207,669 3,273,371 RGD:9068941
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link NW_004955545 2,929,704 2,947,579 RGD:9068941
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link NW_004955432 2,284,283 2,629,631 RGD:9068941
G Ntsr1 neurotensin receptor 1 JBrowse link NW_004955528 1,348,616 1,394,798 RGD:9068941
G Oprk1 opioid receptor kappa 1 JBrowse link NW_004955454 12,741,577 12,751,282 RGD:9068941
G Oprl1 opioid related nociceptin receptor 1 JBrowse link NW_004955528 161,673 184,515 RGD:9068941
G Oprm1 opioid receptor mu 1 JBrowse link NW_004955439 7,870,563 7,923,817 RGD:9068941
G P2rx2 purinergic receptor P2X 2 JBrowse link NW_004955482 418,101 422,058 RGD:9068941
G P2rx3 purinergic receptor P2X 3 JBrowse link NW_004955511 2,389,717 2,410,968 RGD:9068941
G P2ry12 purinergic receptor P2Y12 JBrowse link NW_004955448 2,442,368 2,488,567 RGD:9068941
G Pawr pro-apoptotic WT1 regulator JBrowse link NW_004955405 18,434,711 18,540,710 RGD:9068941
G Pdyn prodynorphin JBrowse link NW_004955415 13,106,087 13,119,497 RGD:9068941
G Penk proenkephalin JBrowse link NW_004955454 15,425,712 15,426,685 RGD:9068941
G Pla2g4a phospholipase A2 group IVA JBrowse link NW_004955406 25,257,361 25,392,079 RGD:9068941
G Pnoc prepronociceptin JBrowse link NW_004955403 50,735,567 50,755,892 RGD:9068941
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link NW_004955408 5,435,117 5,460,361 RGD:9068941
G Prkcb protein kinase C beta JBrowse link NW_004955493 2,395,494 2,710,522 RGD:9068941
G Prkce protein kinase C epsilon JBrowse link NW_004955441 12,642,703 13,142,396 RGD:9068941
G Prkcg protein kinase C gamma JBrowse link NW_004955604 262,182 279,259 RGD:9068941
G Prkcz protein kinase C zeta JBrowse link NW_004955486 8,947,579 9,021,702 RGD:9068941
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link NW_004955425 6,176,335 7,335,867 RGD:9068941
G Prok2 prokineticin 2 JBrowse link NW_004955421 16,325,519 16,339,458 RGD:9068941
G Prokr1 prokineticin receptor 1 JBrowse link NW_004955424 16,287,666 16,301,713 RGD:9068941
G Ptafr platelet activating factor receptor JBrowse link NW_004955452 7,309,854 7,345,579 RGD:9068941
G Ptger1 prostaglandin E receptor 1 JBrowse link NW_004955415 33,063,052 33,067,580 RGD:9068941
G Ptger3 prostaglandin E receptor 3 JBrowse link NW_004955423 21,096,926 21,164,435 RGD:9068941
G Ptger4 prostaglandin E receptor 4 JBrowse link NW_004955426 24,997,811 25,010,822 RGD:9068941
G Ptges3 prostaglandin E synthase 3 JBrowse link NW_004955458 4,203,075 4,209,967 RGD:9068941
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link NW_004955419 5,678,750 5,699,305 RGD:9068941
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link NW_004955406 25,077,988 25,086,259 RGD:9068941
G Pthlh parathyroid hormone like hormone JBrowse link NW_004955505 6,834,533 6,846,909 RGD:9068941
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link NW_004955429 17,980,956 18,049,723 RGD:9068941
G Rgs4 regulator of G protein signaling 4 JBrowse link NW_004955462 13,340,812 13,347,598 RGD:9068941
G Scn10a sodium voltage-gated channel alpha subunit 10 JBrowse link NW_004955427 25,157,179 25,244,020 RGD:9068941
G Scn11a sodium voltage-gated channel alpha subunit 11 JBrowse link NW_004955427 24,917,709 25,109,499 RGD:9068941
G Sin3a SIN3 transcription regulator family member A JBrowse link NW_004955450 2,804,551 2,870,450 RGD:9068941
G Slc12a5 solute carrier family 12 member 5 JBrowse link NW_004955445 11,252,732 11,290,890 RGD:9068941
G Slc17a8 solute carrier family 17 member 8 JBrowse link NW_004955405 36,063,688 36,115,312 RGD:9068941
G Sparc secreted protein acidic and cysteine rich JBrowse link NW_004955408 6,100,123 6,122,460 RGD:9068941
G Stat3 signal transducer and activator of transcription 3 JBrowse link NW_004955451 16,320,326 16,348,505 RGD:9068941
G Syn2 synapsin II JBrowse link NW_004955429 14,676,286 14,724,625 RGD:9068941
G Tac1 tachykinin precursor 1 JBrowse link NW_004955432 13,991,647 13,999,665 RGD:9068941
G Tacr1 tachykinin receptor 1 JBrowse link NW_004955424 10,614,340 10,761,872 RGD:9068941
G Tgfbr1 transforming growth factor beta receptor 1 JBrowse link NW_004955419 26,490,899 26,546,349 RGD:9068941
G Thbd thrombomodulin JBrowse link NW_004955415 30,222,830 30,226,406 RGD:9068941
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
G Tlr4 toll like receptor 4 JBrowse link NW_004955419 10,190,937 10,201,896 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
G Tnfrsf11b TNF receptor superfamily member 11b JBrowse link NW_004955417 24,804,708 24,831,338 RGD:9068941
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link NW_004955413 3,982,670 3,996,320 RGD:9068941
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link NW_004955486 1,790,531 1,817,986 RGD:9068941
G Trpa1 transient receptor potential cation channel subfamily A member 1 JBrowse link NW_004955444 7,876,284 7,922,010 RGD:9068941
G Trpc1 transient receptor potential cation channel subfamily C member 1 JBrowse link NW_004955508 3,143,868 3,211,613 RGD:9068941
G Trpc6 transient receptor potential cation channel subfamily C member 6 JBrowse link NW_004955412 4,905,039 5,019,678 RGD:9068941
G Trpv1 transient receptor potential cation channel subfamily V member 1 JBrowse link NW_004955467 13,221,391 13,239,089 RGD:9068941
G Trpv4 transient receptor potential cation channel subfamily V member 4 JBrowse link NW_004955455 8,744,865 8,781,644 RGD:9068941
G Vip vasoactive intestinal peptide JBrowse link NW_004955439 9,021,923 9,031,783 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11740
    disease of anatomical entity 11302
      nervous system disease 9199
        Neurologic Manifestations 3499
          Pain 263
            Hyperalgesia 179
Path 2
Term Annotations click to browse term
  disease 11740
    disease of anatomical entity 11302
      nervous system disease 9199
        Neurologic Manifestations 3499
          Sensation Disorders 849
            Somatosensory Disorders 291
              Hyperalgesia 179
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.