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ONTOLOGY REPORT - ANNOTATIONS


Term:Disease Susceptibility
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Accession:DOID:9002174 term browser browse the term
Definition:A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases.
Synonyms:exact_synonym: Diatheses;   Diathesis;   Disease Susceptibilities
 primary_id: MESH:D004198;   RDO:0001523
For additional species annotation, visit the Alliance of Genome Resources.


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Disease Susceptibility term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11554173
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:11554173
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 JBrowse link MT 13,543 14,061 RGD:11554173
G Stat4 signal transducer and activator of transcription 4 JBrowse link 9 54,340,649 54,457,753 RGD:11554173
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 JBrowse link 8 6,811,543 6,917,534 RGD:11554173
G Tspan12 tetraspanin 12 JBrowse link 4 48,852,823 48,953,240 RGD:11554173
Bovine Tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
C6 Deficiency, Subtotal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C6 complement C6 JBrowse link 2 54,460,333 54,533,801 RGD:8554872
Genetic Predisposition to Disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:11554173
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11554173
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11554173
G Adh1 alcohol dehydrogenase 1 (class I) JBrowse link 2 243,550,655 243,562,243 RGD:11554173
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:11554173
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:11554173
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:11554173
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:11554173
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:11554173
G Arhgef5 Rho guanine nucleotide exchange factor 5 JBrowse link 4 72,710,775 72,736,415 RGD:11554173
G Bap1 Brca1 associated protein 1 JBrowse link 16 7,336,685 7,345,511 RGD:11554173
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:11554173
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:11554173
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:11554173
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:11554173
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:11554173
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:11554173
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:11554173
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:11554173
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:11554173
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 JBrowse link 4 176,783,287 176,789,143 RGD:11554173
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:11554173
G Mecom MDS1 and EVI1 complex locus JBrowse link 2 117,396,084 117,993,604 RGD:11554173
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:11554173
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:11554173
G Myo18b myosin XVIIIb JBrowse link 12 49,761,100 49,979,745 RGD:11554173
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:11554173
G Ppp3cc protein phosphatase 3 catalytic subunit gamma JBrowse link 15 51,896,427 51,968,075 RGD:11554173
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:11554173
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:11554173
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:11554173
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:11554173
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:11554173
G Zfp266 zinc finger protein 266 JBrowse link 8 21,511,831 21,543,275 RGD:11554173
Latent Tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:8554872
Meningeal Tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:5128510
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10449456
multidrug-resistant tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147828
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147828
ocular tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364832
pleural tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl22 C-C motif chemokine ligand 22 JBrowse link 19 10,674,189 10,681,145 RGD:4891473
G Ccr2 C-C motif chemokine receptor 2 RGD:4145106
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4145106
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4143226
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4143226
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5129700
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144193
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:4889594
pulmonary tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:5128854
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686405
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:4890411
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 JBrowse link 7 104,670,076 104,951,090 RGD:11554173
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129500
G Ccl1 C-C motif chemokine ligand 1 JBrowse link 10 69,534,976 69,537,836 RGD:4891409
RGD:4891408
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:5130906
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:4891439
RGD:11554173
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:4891879
RGD:4892112
G Ccr2 C-C motif chemokine receptor 2 RGD:734715
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4892094
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:4144205
G Cd209 CD209 molecule JBrowse link 12 2,406,879 2,413,324 RGD:11554173
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:4892339
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:5131284
RGD:5131287
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:27095956
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:5135037
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:5135246
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:4780358
G Gbe1 1,4-alpha-glucan branching enzyme 1 JBrowse link 11 7,210,169 7,485,895 RGD:18337291
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:4140932
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:4140932
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:5135524
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145649
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:4990461
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:4889836
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:4142835
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4143180
RGD:5147843
RGD:4143179
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4143180
RGD:4143174
RGD:4143179
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:5128486
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:5128550
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:5128510
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:4143257
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:5128632
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:5128719
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:4889999
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:4143234
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:4889452
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:4891004
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:11554173
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:11554173
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:11554173
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5130746
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:4140932
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:5131510
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4144122
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:6483832
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:6484723
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:5147614
G Sftpa1 surfactant protein A1 JBrowse link 16 18,716,019 18,719,404 RGD:4144874
RGD:4144875
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:5684974
G Tap1 transporter 1, ATP binding cassette subfamily B member JBrowse link 20 3,979,302 3,989,669 RGD:6482248
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:5147851
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:4889525
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:4145304
RGD:4145320
RGD:4145323
RGD:4145355
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144106
RGD:4144122
RGD:4144205
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:5130704
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4143388
RGD:4142835
RGD:4143395
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:4889849
RGD:4889830
RGD:4889842
RGD:4889845
RGD:4889853
renal tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:5128510
RGD:7207069
tuberculosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6767307
G Btnl2 butyrophilin-like 2 JBrowse link 20 4,140,184 4,156,365 RGD:9685035
RGD:9685036
G Ccl1 C-C motif chemokine ligand 1 JBrowse link 10 69,534,976 69,537,836 RGD:4891408
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8554872
RGD:11554173
RGD:7240710
G Cd209 CD209 molecule JBrowse link 12 2,406,879 2,413,324 RGD:8554872
RGD:11554173
RGD:7240710
G Cd209c CD209c molecule JBrowse link 12 2,837,991 2,846,709 RGD:5131181
RGD:5131186
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:4892329
G Ciita class II, major histocompatibility complex, transactivator JBrowse link 10 5,212,621 5,260,641 RGD:5491205
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:8554872
RGD:11554173
RGD:7240710
G Coro1a coronin 1A JBrowse link 1 198,123,883 198,128,890 RGD:11554173
G Cxcl9 C-X-C motif chemokine ligand 9 JBrowse link 14 17,228,832 17,233,743 RGD:5135308
G Has1 hyaluronan synthase 1 JBrowse link 1 59,720,612 59,732,409 RGD:9588638
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8554872
RGD:11554173
RGD:7240710
G Ifngr1 interferon gamma receptor 1 JBrowse link 1 15,062,380 15,080,815 RGD:4144122
RGD:11554173
RGD:7240710
RGD:8554872
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:4987456
G Il22 interleukin 22 JBrowse link 7 61,236,037 61,240,502 RGD:5147402
G Irgm immunity-related GTPase M JBrowse link 10 34,213,885 34,221,968 RGD:7240710
RGD:11554173
G Mapkapk3 MAPK activated protein kinase 3 JBrowse link 8 116,012,126 116,046,012 RGD:8554872
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:11554173
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:5147605
RGD:5147633
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:5684931
RGD:8554872
RGD:11554173
RGD:7240710
RGD:1331525
G Sp110 SP110 nuclear body protein JBrowse link 9 92,593,909 92,618,867 RGD:8554872
RGD:11554173
RGD:7240710
G Sp140 SP140 nuclear body protein JBrowse link 9 92,618,088 92,665,431 RGD:8554872
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581371
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:11554173
RGD:7240710
RGD:8554872
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:7246918
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:8554872
RGD:11554173
RGD:7240710
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144821
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:7246918
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4143229
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:5131209
G Tnfsf8 TNF superfamily member 8 JBrowse link 5 79,664,779 79,691,547 RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:4889839
Tumor Predisposition Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bap1 Brca1 associated protein 1 JBrowse link 16 7,336,685 7,345,511 RGD:7240710
RGD:8554872
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:8554872
G Dnah1 dynein, axonemal, heavy chain 1 JBrowse link 16 7,345,131 7,407,009 RGD:8554872
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:8554872
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:8554872
G Palb2 partner and localizer of BRCA2 JBrowse link 1 192,064,586 192,088,547 RGD:8554872
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:8554872

Term paths to the root
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Term Annotations click to browse term
  disease 15849
    Pathological Conditions, Signs and Symptoms 8392
      Pathologic Processes 5449
        Disease Attributes 544
          Disease Susceptibility 129
            C6 Deficiency, Subtotal 1
            Echo Virus 11 Sensitivity 0
            Genetic Predisposition to Disease + 42
            tuberculosis + 85
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.