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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Bisphosphonate-Associated Osteonecrosis of the Jaw
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Accession:DOID:9002130 term browser browse the term
Definition:Necrotic jaws or other maxillofacial skeleton necrosis associated with bisphosphonate use (see BISPHOSPHONATES). Injury, dental procedures, and trauma can trigger the necrotic process.
Synonyms:exact_synonym: Bisphosphonate Associated Osteonecrosis;   Bisphosphonate Associated Osteonecrosis of the Jaws;   Bisphosphonate Induced Osteonecrosis of the Jaw;   Bisphosphonate Induced Osteonecrosis of the Jaws;   Bisphosphonate Osteonecroses;   Bisphosphonate Osteonecrosis;   Bisphosphonate Related Osteonecrosis of the Jaw;   Bisphosphonate-Associated Osteonecroses;   Osteonecrosis of the Jaws, Bisphosphonate Related
 primary_id: MESH:D059266;   RDO:0010003
For additional species annotation, visit the Alliance of Genome Resources.


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Bisphosphonate-Associated Osteonecrosis of the Jaw term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain treatment ISO associated with Multiple Myeloma RGD PMID:21396799 RGD:11041182 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12691
    Stomatognathic Diseases 890
      Jaw Diseases 279
        Bisphosphonate-Associated Osteonecrosis of the Jaw 1
Path 2
Term Annotations click to browse term
  disease 12691
    disease of anatomical entity 12366
      musculoskeletal system disease 5516
        connective tissue disease 3660
          bone disease 2510
            ischemic bone disease 23
              osteonecrosis 22
                Bisphosphonate-Associated Osteonecrosis of the Jaw 1
paths to the root