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ONTOLOGY REPORT - ANNOTATIONS


Term:Poor Metabolism of Thiopurines, 2
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Accession:DOID:9002041 term browser browse the term
Definition:A severe hematopoietic toxicity upon treatment of patients with standard doses of thiopurines, a class of antineoplastic/immunosuppressant agents that consists of mercaptopurine, thioguanine, and azathioprine. (OMIM)
Synonyms:exact_synonym: THPM2
 primary_id: OMIM:616903
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Poor Metabolism of Thiopurines, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nudt15 nudix hydrolase 15 JBrowse link 15 55,417,774 55,456,698 RGD:8554872
RGD:7240710

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15609
    Nutritional and Metabolic Diseases 4391
      disease of metabolism 4391
        inherited metabolic disorder 1909
          thiopurine S-methyltransferase deficiency 2
            Poor Metabolism of Thiopurines, 2 1
Path 2
Term Annotations click to browse term
  disease 15609
    disease of anatomical entity 14966
      Immune & Inflammatory Diseases 3227
        immune system disease 2645
          hypersensitivity reaction disease 1498
            allergic hypersensitivity disease 558
              drug allergy 104
                thiopurine S-methyltransferase deficiency 2
                  Poor Metabolism of Thiopurines, 2 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.