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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Fungal Eye Infections
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Accession:DOID:9001949 term browser browse the term
Definition:Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.
Synonyms:exact_synonym: Fungal Ocular Infection;   Fungal Ocular Infections;   Ocular Mycoses;   Ocular Mycosis;   Ocular Mycotic Infection;   Ocular Mycotic Infections;   Oculomycoses;   fungal eye infection;   oculomycosis
 primary_id: MESH:D015821
For additional species annotation, visit the Alliance of Genome Resources.


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Fungal Eye Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll like receptor 2 ISO mRNA:increased expression:cornea RGD PMID:19474209 RGD:2312502 NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
JBrowse link
G Tlr4 toll like receptor 4 ISO mRNA:increased expression:cornea RGD PMID:19474209 RGD:2312502 NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
JBrowse link
Fungal Keratitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A treatment ISO mRNA:increased expression:cornea RGD PMID:26963514 RGD:11526921 NCBI chrNW_004936902:436,224...446,435 JBrowse link
G Tlr4 toll like receptor 4 ISO associated with Aspergillosis RGD PMID:20617171 RGD:7794847 NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment ISO mRNA:increased expression:cornea RGD PMID:26963514 RGD:11526921 NCBI chrNW_004936476:18,577,825...18,583,675
Ensembl chrNW_004936476:18,574,381...18,583,647
JBrowse link
G Tslp thymic stromal lymphopoietin disease_progression ISO RGD PMID:29550278 PMID:30853520 RGD:38549371 RGD:38549574 NCBI chrNW_004936531:5,495,872...5,500,462 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13815
    disease by infectious agent 1902
      Bacterial Infections and Mycoses 877
        fungal infectious disease 125
          Fungal Eye Infections 5
            Fungal Keratitis 4
            suppurative uveitis + 0
Path 2
Term Annotations click to browse term
  disease 13815
    disease of anatomical entity 13535
      nervous system disease 11528
        sensory system disease 5757
          eye disease 2697
            Eye Infections 51
              Fungal Eye Infections 5
                Fungal Keratitis 4
                suppurative uveitis + 0
paths to the root