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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Fungal Eye Infections
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Accession:DOID:9001949 term browser browse the term
Definition:Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.
Synonyms:exact_synonym: Fungal Ocular Infection;   Fungal Ocular Infections;   Ocular Mycoses;   Ocular Mycosis;   Ocular Mycotic Infection;   Ocular Mycotic Infections;   Oculomycoses;   fungal eye infection;   oculomycosis
 primary_id: MESH:D015821
 alt_id: RDO:0006923
For additional species annotation, visit the Alliance of Genome Resources.


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Fungal Eye Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 IEP mRNA:increased expression:cornea RGD PMID:19474209 RGD:2312502 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 IEP mRNA:increased expression:cornea RGD PMID:19474209 RGD:2312502 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
Fungal Keratitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A treatment ISO mRNA:increased expression:cornea RGD PMID:26963514, PMID:26963514 RGD:11526921, RGD:11526921 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:20617171 RGD:7794847 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment ISO mRNA:increased expression:cornea RGD PMID:26963514, PMID:26963514, PMID:26963514 RGD:11526921, RGD:11526921, RGD:11526921 NCBI chr 9:14,727,887...14,743,371
Ensembl chr 9:14,727,976...14,809,447
JBrowse link
G Tslp thymic stromal lymphopoietin disease_progression ISO RGD PMID:29550278, PMID:30853520 RGD:38549371, RGD:38549574 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17129
    disease by infectious agent 1903
      Bacterial Infections and Mycoses 786
        fungal infectious disease 131
          Fungal Eye Infections 5
            Fungal Keratitis 4
            suppurative uveitis + 0
Path 2
Term Annotations click to browse term
  disease 17129
    disease of anatomical entity 16476
      nervous system disease 12074
        sensory system disease 5584
          eye disease 2725
            Eye Infections 58
              Fungal Eye Infections 5
                Fungal Keratitis 4
                suppurative uveitis + 0
paths to the root