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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:limb reperfusion injury
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Accession:DOID:9001659 term browser browse the term
Definition:This is adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to one or more limbs, including swelling; hemorrhage; necrosis; and damage from free radicals. A limb is a paired appendage that is evolved from a paired fin.
Synonyms:narrow_synonym: forelimb reperfusion injury;   hindlimb reperfusion injury


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limb reperfusion injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPT glutamic--pyruvic transaminase treatment ISO RGD PMID:36495512 RGD:401717522 NCBI chr13:37,923,757...37,927,843
Ensembl chr13:37,924,422...37,926,156 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17774
    disease of anatomical entity 15146
      cardiovascular system disease 4407
        vascular disease 3103
          Reperfusion Injury 780
            limb reperfusion injury 1
Path 2
Term Annotations click to browse term
  disease 17774
    disease of anatomical entity 15146
      cardiovascular system disease 4407
        vascular disease 3103
          ischemia 1423
            limb ischemia 22
              limb reperfusion injury 1
paths to the root