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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Acute Anterior Uveitis
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Accession:DOID:9001606 term browser browse the term
Definition:Having a sudden onset, sharp rise, and short course of anterior uveitis.
Synonyms:exact_synonym: AAU


show annotations for term's descendants           Sort by:
Acute Anterior Uveitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL2 C-C motif chemokine ligand 2 severity IEP protein:increased expression:aqueous humor (human) RGD PMID:9426952 RGD:8549479 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G HLA-B major histocompatibility complex, class I, B IAGP associated with Inflammatory Bowel Diseases;DNA:polymorphisms:cds:HLA-B*27, HLA-B*58 (human) RGD PMID:12198697 RGD:7364926 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067 		JBrowse link
Endotoxin-Induced Uveitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1B1 aldo-keto reductase family 1 member B treatment ISO RGD PMID:17898287 RGD:8548683 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:18087711 RGD:2298858 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility ISO mRNA:increased expression:uvea, retina (rat) RGD PMID:22267332 PMID:7928184 RGD:8549801, RGD:8551705 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G SERPINF1 serpin family F member 1 ISO protein:decreased expression:retina, plasma (rat) RGD PMID:16368716 RGD:1580133 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G THBD thrombomodulin treatment IDA RGD PMID:22001200 RGD:11038716 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97387
    sensory system disease 20957
      eye disease 7647
        uveal disease 478
          uveitis 220
            Acute Uveitis 7
              Acute Anterior Uveitis 6
                Endotoxin-Induced Uveitis 5
Path 2
Term Annotations click to browse term
  disease 97387
    Pathological Conditions, Signs and Symptoms 53656
      Signs and Symptoms 35476
        Neurologic Manifestations 31894
          sensory system disease 20957
            eye disease 7647
              uveal disease 478
                uveitis 220
                  panuveitis 171
                    anterior uveitis 167
                      Acute Anterior Uveitis 6
                        Endotoxin-Induced Uveitis 5
paths to the root