Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Wounds and Injuries
go back to main search page
Accession:DOID:9001600 term browser browse the term
Definition:Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.
Synonyms:exact_synonym: Injuries;   Injuries, Wounds;   Injury;   Injury and Wounds;   Research Related Injuries;   Research-Related Injury;   Trauma;   Traumas;   Wound;   Wounds;   Wounds, Injury
 primary_id: MESH:D014947;   RDO:0004686
 subset: RGD_JBrowse_slim
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
Wounds and Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:15708862 RGD:5509615 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G ANKRD1 ankyrin repeat domain 1 ISO mRNA, protein:increased expression:multiple RGD PMID:15632022 RGD:5133280 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
JBrowse link
G ARG1 arginase 1 ISO protein:increased expression:wound, fibroblast (rat) RGD PMID:12069499 RGD:634666 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G CALCA calcitonin related polypeptide alpha EXP CTD Direct Evidence: therapeutic CTD PMID:18430544 NCBI chr11:14,966,668...14,972,361
Ensembl chr11:14,966,668...14,972,351
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO mRNA, protein:increased expression:ligament RGD PMID:19327017 RGD:2306564 NCBI chr10:44,292,088...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G DCN decorin ISO RGD PMID:19393425 RGD:2311417 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
JBrowse link
G EGF epidermal growth factor ISO
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:21967610 PMID:15885173 RGD:6906918 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G ENG endoglin disease_progression ISO RGD PMID:23349951 RGD:7248769 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G FGF2 fibroblast growth factor 2 treatment IDA
EXP
ISO
associated with Diabetes Mellitus, Non-Insulin-Dependent
CTD Direct Evidence: therapeutic
protein:increased expression:skin
CTD
RGD
PMID:11842932 PMID:16008728 PMID:21402405 PMID:23603001 PMID:12533868 RGD:2315863, RGD:8655582, RGD:8655580, RGD:2292211 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G GC GC vitamin D binding protein treatment ISO
EXP
associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17852808 PMID:24263389 RGD:11041807 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G HGF hepatocyte growth factor treatment IDA RGD PMID:16572191 RGD:8548635 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HMOX1 heme oxygenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12649161 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HP haptoglobin treatment ISO protein:increased expression:serum
associated with Diabetes Mellitus, Experimental
RGD PMID:11521461 PMID:24263389 RGD:1626378, RGD:11041807 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G ICAM1 intercellular adhesion molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IGF1 insulin like growth factor 1 ISO associated with Rhinosinusitis; mRNA:increased expression:nose:
protein:increased expression:skin:
RGD PMID:20713758 PMID:21296499 RGD:8548883, RGD:8549452 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IL10 interleukin 10 ISO RGD PMID:14715528 RGD:1598466 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:18638276 RGD:2311088 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G LAMA3 laminin subunit alpha 3 EXP CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr18:23,689,443...23,955,066
Ensembl chr18:23,689,453...23,956,222
JBrowse link
G LAMB3 laminin subunit beta 3 EXP CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr 1:209,614,870...209,652,467
Ensembl chr 1:209,614,870...209,652,425
JBrowse link
G LAMC2 laminin subunit gamma 2 EXP CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr 1:183,186,264...183,245,127
Ensembl chr 1:183,186,238...183,245,127
JBrowse link
G LTF lactotransferrin EXP CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
JBrowse link
G LUM lumican EXP CTD Direct Evidence: therapeutic CTD PMID:24367547 NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO RGD PMID:9888422 RGD:9685353 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MMP8 matrix metallopeptidase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11172683 NCBI chr11:102,711,796...102,724,967
Ensembl chr11:102,711,796...102,727,050
JBrowse link
G MPO myeloperoxidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO protein:decreased expression:hypothalamus: RGD PMID:11931711 RGD:9835019 NCBI chr20:64,080,082...64,100,643
Ensembl chr20:64,080,082...64,100,643
JBrowse link
G OPTN optineurin ISO RGD PMID:16109995 RGD:7775038 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO RGD PMID:18205704 RGD:2292158 NCBI chr 7:497,245...520,668
Ensembl chr 7:497,258...520,296
JBrowse link
G PDGFB platelet derived growth factor subunit B treatment ISO
IDA
protein:increased expression:skin RGD PMID:12533868 PMID:3280728 RGD:2292211, RGD:10449501 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO protein:increased expression:skin RGD PMID:12533868 RGD:2292211 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PLAT plasminogen activator, tissue type ISO protein:increased expression:plasma (rat) RGD PMID:25423126 RGD:11541076 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PNOC prepronociceptin ISO protein:decreased expression:hypothalamus: RGD PMID:11931711 RGD:9835019 NCBI chr 8:28,316,979...28,343,355
Ensembl chr 8:28,316,986...28,343,355
JBrowse link
G POSTN periostin ISO protein:increased expression:skin: RGD PMID:22681660 RGD:10040991 NCBI chr13:37,562,585...37,598,839
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA, protein:increased expression:skin, fibroblast RGD PMID:8245406 RGD:2300076 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G SPP1 secreted phosphoprotein 1 EXP CTD Direct Evidence: therapeutic CTD PMID:9525990 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO protein:increased expression:skin RGD PMID:12533868 PMID:17117936 RGD:2292211, RGD:2302090 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:17117936 PMID:18205704 RGD:2302090, RGD:2292158 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD PMID:18205704 RGD:2292158 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO mRNA, protein:increased expression:dorsal root ganglion RGD PMID:16683235 RGD:1600154 NCBI chr  X:47,582,408...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 ISO mRNA, protein:increased expression:carotid artery RGD PMID:10082471 RGD:2290470 NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G VEGFA vascular endothelial growth factor A treatment IDA RGD PMID:23603001 RGD:8655580 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
Acute Heart Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MFN1 mitofusin 1 ISO mRNA, protein:increased expression:heart (rat) RGD PMID:25677476 RGD:12437078 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
JBrowse link
Acute Lung Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment ISO associated wit Escherichia coli Infections RGD PMID:29990483 RGD:40400897 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 severity
treatment
ISO
EXP
IDA
CTD Direct Evidence: therapeutic
associated with Escherichia coli Infections
associated with avian influenza;protein:decreased expression:lung (mouse)
human protein in a mouse model
CTD
RGD
PMID:27302421 PMID:16001071 PMID:29990483 PMID:25391767 PMID:16001071 RGD:32716389, RGD:40400897, RGD:40818412, RGD:32716389 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACVR1 activin A receptor type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21297076 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330
JBrowse link
G ADAR adenosine deaminase RNA specific treatment ISO RGD PMID:18520702 RGD:10755331 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,581,695...154,628,013
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing treatment ISO associated with Sepsis RGD PMID:22156343 PMID:23522481 RGD:5686380, RGD:8695940 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADRA2A adrenoceptor alpha 2A ISO RGD PMID:21542970 RGD:6480481 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO associated with Hyperoxia; protein:decreased expression:bronchoalveolar lavage fluid (rat) RGD PMID:23576805 RGD:7244254 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AKAP12 A-kinase anchoring protein 12 ISO mRNA,protein:increased expression:lung RGD PMID:23912647 RGD:14348970 NCBI chr 6:151,239,815...151,358,559
Ensembl chr 6:151,239,967...151,358,559
JBrowse link
G AKT1 AKT serine/threonine kinase 1 severity ISO RGD PMID:23904165 RGD:38676478 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALB albumin ISO RGD PMID:22592748 RGD:6483494 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:19752233 RGD:5509626 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G APOA1 apolipoprotein A1 EXP CTD Direct Evidence: therapeutic CTD PMID:20972769 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G AQP5 aquaporin 5 ISO associated with Disseminated Intravascular Coagulation;mRNA,protein:decreased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr12:49,961,855...49,965,682
Ensembl chr12:49,961,872...49,965,682
JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 EXP CTD Direct Evidence: therapeutic CTD PMID:20554700 NCBI chr12:102,957,674...102,960,513
Ensembl chr12:102,957,674...102,960,513
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G C3 complement C3 treatment ISO RGD PMID:22763771 RGD:11040808 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) treatment ISO associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP3 caspase 3 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:32062619 PMID:29755641 RGD:13782288 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:29755641 RGD:13782288 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CAT catalase EXP CTD Direct Evidence: therapeutic CTD PMID:15612528 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 treatment ISO RGD PMID:24919947 RGD:10045573 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO mRNA, protein:increased expression:lung RGD PMID:21767135 RGD:6480432 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL4 C-C motif chemokine ligand 4 ISO mRNA, protein:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
RGD PMID:10679105 PMID:21767135 PMID:21906407 RGD:68880, RGD:6480432, RGD:5683874 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO associated with Pancreatitis RGD PMID:17312463 RGD:5688151 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
JBrowse link
G CD36 CD36 molecule ISO associated with Malaria RGD PMID:18483551 RGD:6893505 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO associated with Sepsis;mRNA:increased expression:lung RGD PMID:10069420 RGD:5135253 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO
EXP
mRNA, protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:respiratory system fluid/secretion
associated with Sepsis;mRNA:increased expression:lung
CTD
RGD
PMID:27525872 PMID:15557650 PMID:19106808 PMID:10069420 RGD:5135247, RGD:5147925, RGD:5135253 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO mRNA, protein:increased expression:lung
associated with Reperfusion Injury
RGD PMID:15557650 PMID:7814607 RGD:5135247, RGD:5135256 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO mRNA, protein:increased expression:lung
associated with Reperfusion Injury
RGD PMID:7814607 PMID:15557650 RGD:5135247 RGD:5135256 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 disease_progression IEP associated with sepsis;protein:increased expression:blood serum (human) RGD PMID:28506137 RGD:40925937 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 treatment ISO associated with Pancreatitis RGD PMID:17014919 RGD:7257703 NCBI chr 2:218,125,294...218,137,253
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA:increased expression:lung RGD PMID:18367723 PMID:16882535 RGD:5135235, RGD:5147744 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 treatment ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691
JBrowse link
G DDIT3 DNA damage inducible transcript 3 treatment ISO associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G EDN1 endothelin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16625121 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:20935109 RGD:5131862 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ELANE elastase, neutrophil expressed treatment ISO associated with Shock, Hemorrhagic;
protein:increased expression:perfusate:
RGD PMID:15257085 PMID:17203197 PMID:18283562 RGD:10450548, RGD:10450587, RGD:10450585 NCBI chr19:850,997...856,250
Ensembl chr19:851,014...856,247
JBrowse link
G EPHX1 epoxide hydrolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26840748 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:22051199 RGD:5688354 NCBI chr 8:27,491,143...27,597,559
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 treatment ISO associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,080...64,130,819
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:22804886 RGD:7387313 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased expression: respiratory system fluid/secretion RGD PMID:21964405 RGD:11341740 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FADD Fas associated via death domain treatment ISO associated with Shock, Hemorrhagic RGD PMID:24122010 RGD:11341811 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
JBrowse link
G FAS Fas cell surface death receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FASLG Fas ligand EXP CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia ISO RGD PMID:19106808 RGD:5147925 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa ISO RGD PMID:19106808 RGD:5147925 NCBI chr 1:161,505,430...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb treatment ISO RGD PMID:19106808 RGD:5147925 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,147...161,678,654
JBrowse link
G FGA fibrinogen alpha chain ISO protein:increased expression:blood (rat) RGD PMID:22804886 RGD:7387313 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO associated with Endotoxemia RGD PMID:21528367 RGD:5684427 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO RGD PMID:23576849 RGD:8662452 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO protein:decreased expression:lung (rat) RGD PMID:25581610 RGD:13504847 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:7896613 RGD:7257562 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GZMB granzyme B ISO RGD PMID:20018616 RGD:5135517 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO associated with Endotoxemia
associated with Crush Injuries
associated with Burns
RGD PMID:19766246 PMID:30465396 PMID:23874764 RGD:4892587, RGD:34901874, RGD:10402098 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:16922808 RGD:5508470 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Reperfusion Injury RGD PMID:20850789 PMID:20360627 RGD:4145326, RGD:4140418 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C ISO protein:altered localization:lung (mouse) RGD PMID:19029002 RGD:10054390 NCBI chr14:21,209,147...21,269,442
Ensembl chr14:21,209,136...21,269,494
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 treatment ISO associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17973899 PMID:27525872 PMID:20569121 RGD:8547719 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 treatment ISO RGD PMID:25278421 RGD:39939031 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790
JBrowse link
G IFNG interferon gamma ISO RGD PMID:21767135 RGD:6480432 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 treatment
no_association
ISO
IAGP
DNA:SNP:promoter:rs3021097 (human)
DNA:SNP:promoter:-1082G>A (rs1800896) (human)
associated with Reperfusion Injury;protein:increased expression:lung, plasma
RGD PMID:23902576 PMID:30412745 PMID:30412745 PMID:23801594 RGD:7364984, RGD:14975158, RGD:14975158, RGD:7365008 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 ISO mRNA:increased expression:lung RGD PMID:15461830 RGD:4145512 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL17A interleukin 17A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28600744 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 treatment ISO associated with Myocardial Reperfusion Injury RGD PMID:24223666 RGD:8655952 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1B interleukin 1 beta ISO
EXP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:lung
CTD
RGD
PMID:32062619 PMID:20663306 PMID:22982561 PMID:21767135 PMID:8613550 More... RGD:4142531, RGD:7204498, RGD:6480432, RGD:4143193, RGD:4142807 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 ISO
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:21352201 PMID:21352201 RGD:5144222 NCBI chr 2:102,311,529...102,352,367
Ensembl chr 2:102,311,502...102,352,037
JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO mRNA:increased expression:lung RGD PMID:15970097 PMID:8613550 RGD:4143168, RGD:4143193 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL2 interleukin 2 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:21767135 RGD:6480432 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL22 interleukin 22 ISO RGD PMID:20498020 RGD:4888524 NCBI chr12:68,248,242...68,253,604
Ensembl chr12:68,248,242...68,253,604
JBrowse link
G IL4 interleukin 4 treatment ISO RGD PMID:24681349 RGD:10402798 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL6 interleukin 6 ISO
EXP
protein:increased expression:bronchoalveolar lavage, blood, lung (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:32062619 PMID:19995278 RGD:11062103 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO mRNA, protein:increased expression:lung (mouse) RGD PMID:21577093 RGD:36049795 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622
JBrowse link
G ITGB2 integrin subunit beta 2 ISO RGD PMID:1374449 RGD:6482199 NCBI chr21:44,885,949...44,928,815
Ensembl chr21:44,885,953...44,931,989
JBrowse link
G JAK3 Janus kinase 3 ISO RGD PMID:22359619 RGD:11531100 NCBI chr19:17,824,782...17,848,071
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G KDR kinase insert domain receptor ISO associated with Endotoxemia;mRNA, protein:decreased expression:lung RGD PMID:21528367 RGD:5684427 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G LTB4R2 leukotriene B4 receptor 2 severity ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr14:24,310,140...24,312,038
Ensembl chr14:24,305,734...24,312,053
JBrowse link
G MFN1 mitofusin 1 ISO mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936
JBrowse link
G MFN2 mitofusin 2 ISO mRNA, protein:increased expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 1:11,980,215...12,013,508
Ensembl chr 1:11,980,181...12,015,211
JBrowse link
G MIR155 microRNA 155 treatment ISO associated with sepsis;miRNA:increased expression:lung
associated with Sepsis
RGD PMID:30220274 PMID:27371731 PMID:27371731 PMID:28125526 PMID:31949845 RGD:21066348, RGD:11566124, RGD:11566124, RGD:24922218, RGD:21408593 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR21 microRNA 21 ISO RNA:increased expression:lung RGD PMID:30542412 RGD:41410885 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MIR223 microRNA 223 severity
treatment
ISO RGD PMID:28931657 PMID:32226458 RGD:21408568, RGD:26884341 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MIR330 microRNA 330 ISO associated with Disseminated Intravascular Coagulation;RNA:increased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr19:45,638,994...45,639,087
Ensembl chr19:45,638,994...45,639,087
JBrowse link
G MIR483 microRNA 483 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32062619 NCBI chr11:2,134,134...2,134,209
Ensembl chr11:2,134,134...2,134,209
JBrowse link
G MIR96 microRNA 96 ISO associated with Disseminated Intravascular Coagulation;RNA:increased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769
JBrowse link
G MIR99B microRNA 99b EXP CTD Direct Evidence: therapeutic CTD PMID:33109608 NCBI chr19:51,692,612...51,692,681
Ensembl chr19:51,692,612...51,692,681
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO RGD PMID:23040778 RGD:13207316 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO associated with Sepsis RGD PMID:21567117 RGD:9685338 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:23040778 RGD:13207316 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase ISO associated with Kidney Reperfusion Injury; protein:increased activity:lung RGD PMID:22092133 RGD:6909173 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MT1X metallothionein 1X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16166738 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16166738 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MYLK myosin light chain kinase IAGP
EXP
associated with Sepsis
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19374788 PMID:16399953 RGD:1581052 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 EXP CTD Direct Evidence: therapeutic CTD PMID:24812154 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NGF nerve growth factor ISO RGD PMID:17673270 RGD:5144065 NCBI chr 1:115,285,915...115,338,253
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33012731 NCBI chr 1:247,416,163...247,448,823
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 treatment ISO associated with Sepsis RGD PMID:22575870 RGD:8547530 NCBI chr16:50,693,587...50,733,077
Ensembl chr16:50,693,588...50,734,041
JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:16882535 RGD:5147744 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NPPA natriuretic peptide A IDA RGD PMID:23422200 RGD:7247713 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:24669282 PMID:28065220 RGD:11035223, RGD:13442501 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 3:193,593,149...193,697,811
Ensembl chr 3:193,593,144...193,697,811
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO associated with Shock, Hemorrhagic RGD PMID:21841533 RGD:6480522 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO DNA:hypermethylation RGD PMID:23546543 RGD:11533951 NCBI chr11:77,322,017...77,514,957
Ensembl chr11:77,322,017...77,474,635
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO associated with Pancreatitis, Experimental, Acute RGD PMID:16127429 RGD:11075069 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA,protein:increased expression:lung,blood vessel: RGD PMID:17136598 RGD:9835397 NCBI chr12:79,584,879...79,691,097
Ensembl chr12:79,574,979...79,690,964
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22592748 RGD:6483494 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO associated with Endotoxemia;mRNA, protein:increased expression:lung (mouse) RGD PMID:31167111 RGD:41410778 NCBI chr10:6,144,918...6,254,648
Ensembl chr10:6,144,934...6,254,644
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO associated with endotoxemia RGD PMID:22198681 PMID:11714830 RGD:6482677, RGD:38599213 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980
JBrowse link
G PLA2G2A phospholipase A2 group IIA severity ISO RGD PMID:19235614 RGD:6482722 NCBI chr 1:19,975,431...19,980,434
Ensembl chr 1:19,975,431...19,980,416
JBrowse link
G PLAU plasminogen activator, urokinase treatment ISO associated with Endotoxemia RGD PMID:21473829 PMID:23324284 RGD:5147760, RGD:7241552 NCBI chr10:73,909,182...73,917,497
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO
EXP
protein:decreased expression:lung (rat)
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:21153920 PMID:16083301 RGD:8553030 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PRDM1 PR/SET domain 1 EXP CTD Direct Evidence: therapeutic CTD PMID:33109608 NCBI chr 6:106,046,729...106,109,938
Ensembl chr 6:105,993,463...106,109,939
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:21595935 RGD:6484539 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,379...40,798,374
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment IDA associated with Pseudomonas Infections
associated with Intestinal Reperfusion Injury
RGD PMID:16553944 PMID:18367148 RGD:11100043, RGD:11250405 NCBI chr 2:127,418,143...127,429,246
Ensembl chr 2:127,418,427...127,429,242
JBrowse link
G PROCR protein C receptor treatment ISO RGD PMID:20095324 RGD:13515130 NCBI chr20:35,172,072...35,215,989
Ensembl chr20:35,172,072...35,216,240
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:lung RGD PMID:20926798 PMID:19567182 RGD:5135287, RGD:5135496 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO protein:decreased expression:lung RGD PMID:18420837 PMID:16226776 RGD:5143982, RGD:5144142 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
JBrowse link
G SERPINC1 serpin family C member 1 treatment IDA associated with Endotoxemia RGD PMID:17940748 RGD:11035256 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327
JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO associated with Shock, Hemorrhagic;mRNA:increased expression:lung (rat)
associated with Sepsis
RGD PMID:25934465 PMID:10745022 PMID:18182560 RGD:11075078, RGD:11080967, RGD:11080962 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SERPING1 serpin family G member 1 treatment IDA RGD PMID:11685347 RGD:8661650 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171
JBrowse link
G SFTPA1 surfactant protein A1 IEP mRNA, protein:increased expression:pneumocyte RGD PMID:8569184 RGD:4143451 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455
JBrowse link
G SFTPD surfactant protein D EXP CTD Direct Evidence: therapeutic CTD PMID:30060251 NCBI chr10:79,937,740...79,982,236
Ensembl chr10:79,937,467...79,982,614
JBrowse link
G SLPI secretory leukocyte peptidase inhibitor severity
treatment
ISO associated with Endotoxemia RGD PMID:10092827 PMID:25466948 RGD:9999422, RGD:9999425 NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564
JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:19797759 RGD:5147812 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:lung RGD PMID:18523300 RGD:5147819 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
JBrowse link
G TFF1 trefoil factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19880587 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535
JBrowse link
G TFF2 trefoil factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19880587 NCBI chr21:42,346,357...42,350,994
Ensembl chr21:42,346,357...42,350,997
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16100012 PMID:25278421 RGD:39939031 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G THBD thrombomodulin treatment ISO
IMP
associated with Endotoxemia RGD PMID:19342415 PMID:20095324 PMID:19536047 RGD:5131887, RGD:13515130, RGD:5685372 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 severity ISO RGD PMID:10092827 RGD:9999422 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:19567182 RGD:5135496 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNF tumor necrosis factor treatment
no_association
ISO
IAGP
mRNA, protein:increased expression:lung
associated with Liver Reperfusion Injury
DNA:SNP:promoter:rs1799964 (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
protein:increased expression:respiratory system fluid/secretion
RGD PMID:21767135 PMID:11129814 PMID:30412745 PMID:30412745 PMID:19106808 RGD:6480432, RGD:14995473, RGD:14975158, RGD:14975158, RGD:5147925 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 EXP CTD Direct Evidence: therapeutic CTD PMID:26313688 NCBI chr 2:151,357,592...151,380,046
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates
ameliorates
ISO RGD PMID:26832696 PMID:26832696 RGD:127284840, RGD:127284840 NCBI chr 6:41,267,385...41,286,692
Ensembl chr 6:41,267,926...41,286,682
JBrowse link
G TXN thioredoxin EXP CTD Direct Evidence: therapeutic CTD PMID:16298680 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G VEGFA vascular endothelial growth factor A ISO associated with Endotoxemia;mRNA, protein:altered expression:lung, plasma RGD PMID:21528367 RGD:5684427 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VIP vasoactive intestinal peptide ISO
EXP
associated with Endotoxemia
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:8643465 PMID:20441697 RGD:4145303 NCBI chr 6:152,750,797...152,759,765
Ensembl chr 6:152,750,797...152,759,765
JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:9655743 RGD:13209002 NCBI chr 2:31,334,320...31,414,777
Ensembl chr 2:31,334,321...31,414,742
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A severity ISO associated with toxic shock syndrome RGD PMID:23422584 RGD:39938961 NCBI chr 1:37,474,518...37,484,377
Ensembl chr 1:37,474,580...37,484,377
JBrowse link
anthracosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr 1:160,151,603...160,186,980
Ensembl chr 1:160,151,586...160,186,980
JBrowse link
G FLACC1 flagellum associated containing coiled-coil domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr 2:201,288,271...201,364,285
Ensembl chr 2:201,288,271...201,357,398
JBrowse link
G FNBP1P1 formin binding protein 1 pseudogene 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr 2:74,120,519...74,121,816
Ensembl chr 2:74,120,680...74,123,218
JBrowse link
G IL1A interleukin 1 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist EXP CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G RBM26 RNA binding motif protein 26 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr13:79,311,827...79,406,255
Ensembl chr13:79,311,824...79,406,477
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
Anthracycline-induced Cardiotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility IAGP DNA:missense mutation:cds:p.G671V (human) RGD PMID:16330681 RGD:11041175 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G CAPN2 calpain 2 treatment ISO RGD PMID:25634181 RGD:13792617 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit IAGP associated with Leukemia, Myeloid, Acute;DNA:SNP:exon:p.K751Q (rs13181) (human) RGD PMID:24284041 RGD:11252190 NCBI chr19:45,349,837...45,370,647
Ensembl chr19:45,349,837...45,370,918
JBrowse link
Aortic Rupture term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:2346371 PMID:25449986 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G EDN2 endothelin 2 IEP RGD PMID:11947982 RGD:1580915 NCBI chr 1:41,478,775...41,484,699
Ensembl chr 1:41,478,775...41,484,683
JBrowse link
G FBN1 fibrillin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,313...48,645,721
JBrowse link
G MMP2 matrix metallopeptidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP9 matrix metallopeptidase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NPR1 natriuretic peptide receptor 1 ISO associated with Hypertension RGD PMID:9405681 RGD:737701 NCBI chr 1:153,678,649...153,693,992
Ensembl chr 1:153,678,688...153,693,992
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16549638 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980
JBrowse link
asbestosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26699812 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ATF6 activating transcription factor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
JBrowse link
G CFD complement factor D EXP CTD Direct Evidence: marker/mechanism CTD PMID:22832039 NCBI chr19:859,664...863,641
Ensembl chr19:859,664...863,641
JBrowse link
G CLCA1 chloride channel accessory 1 ISO mRNA, protein:increased expression:lung RGD PMID:17637221 RGD:4145655 NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 IEP mRNA:decreased expression:leukocyte RGD PMID:20514434 RGD:4892076 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G DDIT3 DNA damage inducible transcript 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility IAGP DNA:SNP:exon:p.Y113H (rs1051740) (human) RGD PMID:17159790 RGD:4889408 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion: : RGD PMID:9055949 RGD:5490588 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17563610
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:8473757 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24142982 NCBI chr 1:247,416,163...247,448,823
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G NOS2 nitric oxide synthase 2 ISO
EXP
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:lung
CTD
RGD
PMID:12160931 PMID:12160931 PMID:12051993 RGD:4891441, RGD:4891438 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G PRDX1 peroxiredoxin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PRDX2 peroxiredoxin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
JBrowse link
G SERPINA1 serpin family A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12368052 NCBI chr14:94,376,747...94,390,654
Ensembl chr14:94,376,747...94,390,693
JBrowse link
G SPP1 secreted phosphoprotein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16221779 PMID:21514415 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G TNC tenascin C IEP protein:increased expression:pleura RGD PMID:10950882 RGD:4889594 NCBI chr 9:115,019,575...115,118,244
Ensembl chr 9:115,019,575...115,118,257
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:8473757 PMID:20486865 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TPM4 tropomyosin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr19:16,067,507...16,103,005
Ensembl chr19:16,067,021...16,103,002
JBrowse link
Asphyxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha ISO mRNA, protein:increased expression:myocardium, lung (rat) RGD PMID:17285858 RGD:9068458 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G IFT80 intraflagellar transport 80 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17468754 NCBI chr 3:160,256,986...160,399,225
Ensembl chr 3:160,256,986...160,399,880
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:18620825 RGD:4890002 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G SOX4 SRY-box transcription factor 4 ISO RGD PMID:12011571 RGD:1581119 NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619
JBrowse link
asphyxia neonatorum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO mRNA:increased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr19:45,349,837...45,370,647
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit ISO mRNA:decreased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr 2:127,257,290...127,294,166
Ensembl chr 2:127,257,290...127,294,166
JBrowse link
G GSTM1 glutathione S-transferase mu 1 severity IAGP DNA:deletion, haplotype:: (human) RGD PMID:21058530 RGD:12792218 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G HTRA2 HtrA serine peptidase 2 treatment ISO protein:increased expression:kidney: RGD PMID:20704803 RGD:10402931 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,725...74,533,332
JBrowse link
G MAP2 microtubule associated protein 2 ISO RGD PMID:21858873 RGD:6483085 NCBI chr 2:209,424,047...209,734,118
Ensembl chr 2:209,424,047...209,734,118
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO protein:increased expression:hippocampus: RGD PMID:15453273 RGD:9999183 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,410...43,773,278
JBrowse link
G PSEN1 presenilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr14:73,136,436...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
G PSEN2 presenilin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 1:226,870,594...226,903,829
Ensembl chr 1:226,870,184...226,927,726
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G S100B S100 calcium binding protein B IEP protein:increased expression:urine RGD PMID:14707571 RGD:5508819 NCBI chr21:46,598,604...46,605,243
Ensembl chr21:46,598,604...46,605,208
JBrowse link
G SOD1 superoxide dismutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G XRCC1 X-ray repair cross complementing 1 ISO mRNA:increased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473
JBrowse link
berylliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme EXP CTD Direct Evidence: marker/mechanism CTD PMID:10194187 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G BTNL2 butyrophilin like 2 susceptibility IAGP
EXP
DNA:SNP: :rs3117099(human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17927685 PMID:17927685 RGD:9685029 NCBI chr 6:32,393,339...32,408,879
Ensembl chr 6:32,393,963...32,407,128
JBrowse link
G CCR5 C-C motif chemokine receptor 5 disease_progression IAGP DNA:polymorphisms:5' utr:multiple (human) RGD PMID:20075058 RGD:4892065 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
G CD28 CD28 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:12952926 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:16766924 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8105536 PMID:11551429 PMID:14662898 PMID:15273960 PMID:17927685 More... NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) EXP CTD Direct Evidence: marker/mechanism CTD PMID:16272364 NCBI chr 6:33,112,516...33,129,113
Ensembl chr 6:33,112,451...33,129,084
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16272364 PMID:17927685 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HMOX1 heme oxygenase 1 IEP protein:increased activity:sputum RGD PMID:19453654 RGD:4145349 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:8977230 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8428540 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G TGFB1 transforming growth factor beta 1 severity IAGP
EXP
DNA:polymorphisms: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15750822 PMID:17785866 PMID:17785866 RGD:4145294 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:8428540 PMID:12449171 PMID:15127972 PMID:16980557 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
Birth Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:multiple organs (rat) RGD PMID:18554634 RGD:4890426 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
Blast Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein ISO RGD PMID:24224042 RGD:10054251 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
Bone Fractures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:19884440 RGD:2317529 NCBI chr10:45,374,209...45,446,121
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEP associated with kidney failure, chronic; RGD PMID:21784896 RGD:7207231 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BMP2 bone morphogenetic protein 2 EXP CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
JBrowse link
G BMP7 bone morphogenetic protein 7 EXP CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G COL1A1 collagen type I alpha 1 chain IMP RGD PMID:8432871 RGD:734801 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G ESR1 estrogen receptor 1 no_association IAGP DNA:SNP:intron:rs9340799 (human)
DNA:SNP, repeat:promoter:rs2234693 (human)
RGD PMID:15523071 PMID:15523071 RGD:10045827, RGD:10045827 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G FAM210A family with sequence similarity 210 member A EXP CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr18:13,663,347...13,726,558
Ensembl chr18:13,663,347...13,726,663
JBrowse link
G FGF2 fibroblast growth factor 2 IDA associated with Diabetes Mellitus, Experimental RGD PMID:8033826 RGD:2315907 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G GDF2 growth differentiation factor 2 EXP CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588
JBrowse link
G IRX5 iroquois homeobox 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22581230 NCBI chr16:54,930,865...54,934,485
Ensembl chr16:54,930,865...54,934,485
JBrowse link
G LRP5 LDL receptor related protein 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr11:68,298,866...68,449,275
Ensembl chr11:68,312,591...68,449,275
JBrowse link
G MEPE matrix extracellular phosphoglycoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 4:87,821,398...87,846,792
Ensembl chr 4:87,821,411...87,846,817
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:21788831 RGD:6771211 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18795192 RGD:5135218 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTH parathyroid hormone IEP
EXP
associated with Renal Insufficiency, Chronic; protein:increased expression:serum (human)
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:16094769 PMID:23043229 RGD:7242731 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO RGD PMID:21252473 RGD:11252151 NCBI chr21:35,372,507...35,580,764
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO RGD PMID:21252473 RGD:11252151 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO RGD PMID:21252473 RGD:11252151 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G SLC25A13 solute carrier family 25 member 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 7:96,120,220...96,322,127
Ensembl chr 7:96,120,220...96,322,147
JBrowse link
G SMAD6 SMAD family member 6 ISO RGD PMID:11920662 RGD:724455 NCBI chr15:66,702,110...66,782,849
Ensembl chr15:66,702,236...66,782,849
JBrowse link
G SOX9 SRY-box transcription factor 9 ISO RGD PMID:21252473 RGD:11252151 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 2:54,456,327...54,671,446
Ensembl chr 2:54,456,317...54,671,446
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20358619 NCBI chr 3:30,606,472...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15071724 NCBI chr 1:12,166,948...12,209,222
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
brain compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFL1 cofilin 1 treatment IEP RGD PMID:25708984 RGD:12738361 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:26448536 RGD:13506960 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:26448536 RGD:13506960 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:26448536 RGD:13506960 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:27113205 RGD:11062140 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
Brain Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 treatment ISO RGD PMID:21107131 RGD:12791995 NCBI chr11:17,392,498...17,476,849
Ensembl chr11:17,392,498...17,476,894
JBrowse link
G ACAN aggrecan ISO mRNA:increased expression:fascia dentata (rat) RGD PMID:18511192 RGD:2315807 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353
JBrowse link
G ACTR2 actin related protein 2 ISO mRNA, protein:decreased expression:hippocampus (rat) RGD PMID:22120305 RGD:11530046 NCBI chr 2:65,227,831...65,271,253
Ensembl chr 2:65,227,788...65,271,253
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:16689670 RGD:2325298 NCBI chr18:904,384...912,172
Ensembl chr18:904,871...912,172
JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO mRNA:increased expression:frontal cortex RGD PMID:20974230 RGD:5688366 NCBI chr 8:26,738,113...26,870,994
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:increased expression:brain (rat) RGD PMID:22915134 PMID:24859607 PMID:22491548 RGD:7245513, RGD:8696001, RGD:7245557 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AIF1 allograft inflammatory factor 1 ISO protein:increased expression:cerebral cortex (rat) RGD PMID:19520144 RGD:2313020 NCBI chr 6:31,615,212...31,617,015
Ensembl chr 6:31,615,217...31,617,021
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nucleus: RGD PMID:12091479 RGD:10053567 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEP protein:increased phosphorylation:brain, neuron RGD PMID:16234845 RGD:5509090 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALB albumin EXP CTD Direct Evidence: marker/mechanism CTD PMID:7909931 PMID:17188501 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor IEP protein:increased expression:urine RGD PMID:14592616 RGD:6904155 NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
JBrowse link
G ANK3 ankyrin 3 ISO RGD PMID:20557305 RGD:6767288 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490
JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A ISO RGD PMID:24385964 RGD:10401136 NCBI chr15:68,778,535...68,820,895
Ensembl chr15:68,778,535...68,820,897
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO protein:increased expression:cerebral cortex RGD PMID:11567033 RGD:2325751 NCBI chr12:98,645,141...98,735,433
Ensembl chr12:98,645,290...98,735,433
JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO mRNA:increased expression:brain RGD PMID:12707777 RGD:2301208 NCBI chr11:6,395,124...6,419,453
Ensembl chr11:6,395,124...6,419,414
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11447995 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G APOD apolipoprotein D ISO mRNA, protein:increased expression:cerebral cortex, glia cell, neuron RGD PMID:10501208 RGD:2311202 NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033
JBrowse link
G APOE apolipoprotein E IEA GAD PMID:15118671 RGD:1331525 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APP amyloid beta precursor protein IEP protein:increased expression:hippocampus RGD PMID:16300758 RGD:10054281 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G AQP4 aquaporin 4 ISO protein:increased expression:cerebral cortex RGD PMID:21083433 PMID:21488209 RGD:5148014, RGD:5148034 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
JBrowse link
G ASIC1 acid sensing ion channel subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr12:50,057,596...50,083,622
Ensembl chr12:50,057,548...50,083,611
JBrowse link
G ASTN1 astrotactin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr 1:176,855,117...177,164,854
Ensembl chr 1:176,857,302...177,164,973
JBrowse link
G ATG12 autophagy related 12 ISO protein:altered localization:brain RGD PMID:18059433 RGD:2301217 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d treatment ISO RGD PMID:26813465 RGD:13800884 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985
JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO mRNA:increased expression:cerebral cortex RGD PMID:17244947 RGD:2300372 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201
JBrowse link
G BAD BCL2 associated agonist of cell death ISO mRNA, protein:increased expression:cerebral cortex RGD PMID:15941375 RGD:2292694 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCAT1 branched chain amino acid transaminase 1 ISO Protein:increased expression:neurons RGD PMID:10686349 RGD:631308 NCBI chr12:24,810,024...24,949,101
Ensembl chr12:24,810,024...24,949,101
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:18093155 PMID:20888848 RGD:2293059, RGD:10054247 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BDNF brain derived neurotrophic factor IEP
EXP
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:15500971 PMID:21269288 PMID:20544832 RGD:4891136 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:neuron, astrocyte
protein:increased expression:hippocampus
protein:increased expression:brain
RGD PMID:18500386 PMID:24221859 PMID:16874043 RGD:6483098, RGD:11558018, RGD:6483314 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO mRNA, protein:increased expression:brain, astrocyte, neuron RGD PMID:15453988 RGD:2293136 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO protein:increased expression:brain, astrocyte, neuron RGD PMID:16388909 RGD:2289020 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO mRNA:increased expression:dentate gyrus, neuron RGD PMID:9080432 RGD:5129488 NCBI chr 2:202,376,310...202,567,751
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G BYSL bystin like ISO mRNA, protein:increased expression:substantia nigra, striatum (rat) RGD PMID:15305856 RGD:2316201 NCBI chr 6:41,921,499...41,933,046
Ensembl chr 6:41,921,499...41,933,046
JBrowse link
G C1QA complement C1q A chain ISO RGD PMID:23808389 RGD:10054313 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,636,628...22,639,678
JBrowse link
G C3 complement C3 ISO RGD PMID:23808389 RGD:10054313 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO RGD PMID:25089700 RGD:11576302 NCBI chr  X:41,514,934...41,923,554
Ensembl chr  X:41,514,934...41,923,554
JBrowse link
G CASP1 caspase 1 ISO mRNA, protein:increased expression:brain RGD PMID:17188500 RGD:2315917 NCBI chr11:105,025,443...105,035,591
Ensembl chr11:105,025,443...105,035,250
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) severity ISO mRNA, protein:increased expression, increased activity:cerebral cortex, hippocampus, neuron, astrocyte RGD PMID:14675152 RGD:2311485 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 ISO protein:altered localization RGD PMID:15590916 RGD:1624191 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CAST calpastatin severity ISO mRNA:increased expression:cerebral cortex RGD PMID:15307896 RGD:5509821 NCBI chr 5:96,662,037...96,774,683
Ensembl chr 5:96,525,267...96,779,595
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO
EXP
protein:increased expression:brain, neuron
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:19210118 PMID:11113322 RGD:2306999, RGD:9587789 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL20 C-C motif chemokine ligand 20 treatment ISO RGD PMID:22040257 RGD:7483630 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:hippocampus RGD PMID:24344922 RGD:8552265 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
G CD14 CD14 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,701
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:23924471 RGD:7248749 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CD40LG CD40 ligand treatment ISO RGD PMID:11755016 PMID:25972624 RGD:8547803, RGD:11344972 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:increased expression:nucleus: RGD PMID:9914434 RGD:8662346 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO mRNA, protein:increased expression:cerebral cortex (mouse) RGD PMID:19833158 RGD:10401206 NCBI chr19:33,299,934...33,302,564
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO
EXP
mRNA, protein:increased expression:cerebral cortex (mouse)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:19833158 RGD:10401206 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CES1 carboxylesterase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr16:55,802,851...55,833,127
Ensembl chr16:55,802,851...55,833,337
JBrowse link
G CFB complement factor B EXP CTD Direct Evidence: marker/mechanism CTD PMID:17474994 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:32,030,462...32,173,018
Ensembl chr15:31,923,438...32,173,018
JBrowse link
G CKMT1B creatine kinase, mitochondrial 1B treatment ISO RGD PMID:24252176 RGD:11565089 NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901
JBrowse link
G CLEC4E C-type lectin domain family 4 member E EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr12:8,533,305...8,541,327
Ensembl chr12:8,533,305...8,540,905
JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase ISO protein:increased expression:hippocampus RGD PMID:20215974 RGD:6483336 NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740
JBrowse link
G COMT catechol-O-methyltransferase ISO protein:increased expression:hippocampus RGD PMID:17240060 RGD:2289740 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G CRP C-reactive protein disease_progression IEP RGD PMID:24456846 RGD:9585646 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF2 colony stimulating factor 2 disease_progression ISO RGD PMID:21515263 RGD:5686795 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21549006 PMID:24239694 RGD:11039431 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 ISO protein:altered expression:cerebral cortex RGD PMID:19473238 RGD:5686860 NCBI chr15:75,674,322...75,712,848
Ensembl chr15:75,674,322...75,712,848
JBrowse link
G CUL5 cullin 5 ISO mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:17010517 RGD:2301432 NCBI chr11:108,008,733...108,107,766
Ensembl chr11:108,008,898...108,107,761
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO mRNA:increased expression:choroid plexus, cerebral cortex RGD PMID:19471279 RGD:5135009 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO protein:increased expression:brain, neuron RGD PMID:19210118 RGD:2306999 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO mRNA:increased expression:hindbrain RGD PMID:16329132 RGD:1599699 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP4F12 cytochrome P450 family 4 subfamily F member 12 ISO RGD PMID:18847377 RGD:2301705 NCBI chr19:15,673,023...15,698,819
Ensembl chr19:15,673,018...15,697,174
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:15774263 RGD:7243841 NCBI chr 5:39,460,870...39,462,304
Ensembl chr 5:39,371,675...39,462,300
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:19429151 RGD:9588608 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 ISO protein:increased degradation:cerebral cortex, hippocampus RGD PMID:17402852 RGD:2303056 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18509630 RGD:2311580 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DUSP5 dual specificity phosphatase 5 ISO mRNA:increased expression:cerebral cortex RGD PMID:12503083 RGD:2317873 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:11526986 RGD:10395358 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
JBrowse link
G EIF3E eukaryotic translation initiation factor 3 subunit E treatment ISO RGD PMID:22960363 RGD:10395371 NCBI chr 8:108,201,216...108,248,734
Ensembl chr 8:108,162,787...108,443,496
JBrowse link
G ELK1 ETS transcription factor ELK1 ISO RGD PMID:15362724 RGD:7488910 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,521...47,650,604
JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO RGD PMID:22960363 RGD:10395371 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPHA4 EPH receptor A4 IEP protein:increased expression, increased activity:astrocyte RGD PMID:22318127 RGD:5688763 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:21075124 RGD:5688356 NCBI chr 8:27,491,143...27,597,559
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G EPO erythropoietin treatment IDA
EXP
ISO
CTD Direct Evidence: therapeutic
mRNA:increased expression:brain:
CTD
RGD
PMID:20833152 PMID:23063952 PMID:18093155 RGD:10401061, RGD:2293059 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G EPOR erythropoietin receptor ISO mRNA:increased expression:brain: RGD PMID:18093155 RGD:2293059 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342
JBrowse link
G F2 coagulation factor II, thrombin severity IDA RGD PMID:21355766 RGD:5147766 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:hippocampus
associated with Hyperoxia
RGD PMID:16078565 PMID:19107989 RGD:1600354, RGD:8662854 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FGF2 fibroblast growth factor 2 EXP CTD Direct Evidence: therapeutic CTD PMID:21269288 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FMR1 FMRP translational regulator 1 ISO protein:altered localization:hippocampus (rat) RGD PMID:16510718 RGD:11667962 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,919...147,951,125
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:9630518 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOXP1 forkhead box P1 treatment ISO RGD PMID:26842647 RGD:11561903 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,708...71,583,989
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO protein:decreased expression:hippocampus RGD PMID:18501200 RGD:2307353 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:26,543,552...26,773,763
Ensembl chr15:26,543,546...26,939,539
JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:26,971,181...27,541,984
Ensembl chr15:26,971,181...27,541,984
JBrowse link
G GDNF glial cell derived neurotrophic factor ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 5:37,812,677...37,840,044
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO RGD PMID:23485053 RGD:8662424 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA5 gap junction protein alpha 5 ISO protein:increased expression:cerebral artery RGD PMID:21895483 RGD:7207391 NCBI chr 1:147,756,199...147,781,127
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GPX1 glutathione peroxidase 1 ISO mRNA:decreased expression:hippocampus, neuron RGD PMID:15791111 RGD:2306624 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G GRM8 glutamate metabotropic receptor 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:126,438,598...127,252,941
Ensembl chr 7:126,438,598...127,253,093
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24675465 PMID:22643085 RGD:10045646 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSN gelsolin ISO RGD PMID:14588109 RGD:1599864 NCBI chr 9:121,201,483...121,332,844
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO mRNA,protein:decreased expression:hippocampus: RGD PMID:11726545 RGD:9686434 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:22915134 RGD:7245513 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18562561 RGD:5508455 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:23470432 RGD:10755702 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HP haptoglobin ISO mRNA:increased expression:liver RGD PMID:23172820 RGD:11041806 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A ISO
EXP
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:21549006 RGD:5147593 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:cerebral white matter (rat) RGD PMID:22067617 RGD:5688785 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO RGD PMID:11746764 RGD:6480530 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:22465320 RGD:6482178 NCBI chr10:90,738,693...90,858,039
Ensembl chr10:90,740,823...90,858,039
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:brain: RGD PMID:16230799 RGD:11522716 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNL3 interferon lambda 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr19:39,243,455...39,245,250
Ensembl chr19:39,243,553...39,245,129
JBrowse link
G IGF1 insulin like growth factor 1 treatment IDA human protein in a rat model RGD PMID:9344566 RGD:12904928 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF2 insulin like growth factor 2 ISO mRNA:decreased expression:brain RGD PMID:11123717 RGD:5509972 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,141,238
JBrowse link
G IL10 interleukin 10 severity
treatment
IEP
EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21549006 PMID:23075771 PMID:23971414 RGD:7364822, RGD:7364983 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:67,307,351...67,398,724
Ensembl chr 1:67,307,364...67,398,724
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977
JBrowse link
G IL16 interleukin 16 ISO RGD PMID:17983426 RGD:5024939 NCBI chr15:81,196,879...81,314,058
Ensembl chr15:81,159,575...81,314,058
JBrowse link
G IL17RD interleukin 17 receptor D EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:57,089,982...57,170,317
Ensembl chr 3:57,089,982...57,170,306
JBrowse link
G IL18 interleukin 18 severity ISO mRNA, protein:increased expression:brain RGD PMID:17188500 PMID:17188500 RGD:2315917, RGD:2315917 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL18R1 interleukin 18 receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:102,355,796...102,398,777
Ensembl chr 2:102,311,529...102,398,777
JBrowse link
G IL1A interleukin 1 alpha ISO
EXP
mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:16024175 RGD:2311098 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta ISO
EXP
mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
protein:increased expression:brain, cerebrospinal fluid
mRNA, protein:increased expression:brain
CTD
RGD
PMID:19800810 PMID:21549006 PMID:16024175 PMID:22503903 PMID:17612572 RGD:2311098, RGD:6482651, RGD:1626652 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1R1 interleukin 1 receptor type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 2:102,069,638...102,179,874
Ensembl chr 2:102,064,544...102,179,874
JBrowse link
G IL1RN interleukin 1 receptor antagonist EXP CTD Direct Evidence: therapeutic CTD PMID:25665855 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL2 interleukin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL3 interleukin 3 disease_progression ISO
IEP
protein: increased expression: brain: microdialysis perfusate RGD PMID:21515263 PMID:20717122 RGD:5686795, RGD:5686886 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
JBrowse link
G IL31RA interleukin 31 receptor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:55,840,334...55,922,854
Ensembl chr 5:55,851,357...55,922,854
JBrowse link
G IL4 interleukin 4 ISO protein:decreased expression:plasma RGD PMID:24519543 RGD:10402802 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:24602693 PMID:24530657 RGD:11522766, RGD:11522770 NCBI chr 5:132,539,194...132,556,864
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 ISO
EXP
protein:increased expression:cerebrospinal fluid (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19800810 PMID:21549006 PMID:23159883 PMID:10027774 RGD:11049549 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL7 interleukin 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 8:78,675,870...78,806,830
Ensembl chr 8:78,675,743...78,805,523
JBrowse link
G IL9R interleukin 9 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:155,997,631...156,013,017
NCBI chr  Y:57,184,151...57,199,537
Ensembl chr  X:155,997,581...156,010,817
JBrowse link
G IRF1 interferon regulatory factor 1 ISO
EXP
mRNA:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:12503083 RGD:2317873 NCBI chr 5:132,481,609...132,490,789
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21596098 RGD:6483023 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:20861444 RGD:8662901 NCBI chr 1:160,037,467...160,070,160
Ensembl chr 1:159,998,651...160,070,160
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:cerebral cortex RGD PMID:21307798 PMID:19733172 RGD:5684382, RGD:5684402 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G LEP leptin ISO RGD PMID:21276361 RGD:5128517 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LSG1 large 60S subunit nuclear export GTPase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr 3:194,640,788...194,672,191
Ensembl chr 3:194,640,791...194,672,463
JBrowse link
G LY86 lymphocyte antigen 86 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 6:6,588,639...6,654,982
Ensembl chr 6:6,588,108...6,654,983
JBrowse link
G MAG myelin associated glycoprotein susceptibility ISO RGD PMID:17156367 RGD:9685230 NCBI chr19:35,292,161...35,313,807
Ensembl chr19:35,292,125...35,313,807
JBrowse link
G MAP1B microtubule associated protein 1B ISO protein:increased expression, increased phosphorylation:brain RGD PMID:10906717 RGD:2304029 NCBI chr 5:72,107,475...72,209,565
Ensembl chr 5:72,107,234...72,209,565
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:24221859 RGD:11558018 NCBI chr20:34,546,823...34,560,345
Ensembl chr20:34,546,854...34,560,345
JBrowse link
G MAP2 microtubule associated protein 2 ISO protein:decreased expression:cerebral cortex, neuron RGD PMID:21401443 PMID:20568963 RGD:6483087, RGD:6483089 NCBI chr 2:209,424,047...209,734,118
Ensembl chr 2:209,424,047...209,734,118
JBrowse link
G MBL2 mannose binding lectin 2 disease_progression ISO RGD PMID:18183030 RGD:12910935 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MBP myelin basic protein ISO RGD PMID:18583256 RGD:7349333 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683
JBrowse link
G MDM2 MDM2 proto-oncogene ISO protein:increased expression:brain cortex (rat) RGD PMID:15165363 RGD:2317397 NCBI chr12:68,808,149...68,850,686
Ensembl chr12:68,808,177...68,845,544
JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:15922484 RGD:1641989 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MIR132 microRNA 132 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:2,049,908...2,050,008
Ensembl chr17:2,049,908...2,050,008
JBrowse link
G MIR144 microRNA 144 ISO RGD PMID:25089700 RGD:11576302 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618
JBrowse link
G MIR153-2 microRNA 153-2 ISO RGD PMID:25089700 RGD:11576302 NCBI chr 7:157,574,336...157,574,422
Ensembl chr 7:157,574,336...157,574,422
JBrowse link
G MIR183 microRNA 183 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:129,774,905...129,775,014
Ensembl chr 7:129,774,905...129,775,014
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19631748 PMID:16671440 PMID:24661104 RGD:1582656, RGD:13207312 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II ISO mRNA, protein:increased expression:hippocampus RGD PMID:11686499 RGD:2302298 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269
JBrowse link
G MT2A metallothionein 2A ISO mRNA:increased expression:liver (mouse)
mRNA:increased expression:dentate gyrus (rat)
RGD PMID:22363575 PMID:15650329 RGD:6483812, RGD:6483847 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MT3 metallothionein 3 treatment ISO RGD PMID:16314047 PMID:10595827 PMID:10218634 RGD:6480628, RGD:9685805, RGD:9685803 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G MYOC myocilin ISO mRNA:increased expression:cerebral cortex (rat) RGD PMID:12799138 RGD:7401267 NCBI chr 1:171,635,417...171,652,688
Ensembl chr 1:171,635,417...171,652,688
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:lung: RGD PMID:18787991 PMID:25089700 RGD:5134971, RGD:11576302 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NGB neuroglobin severity ISO RGD PMID:21915648 RGD:9743963 NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206
JBrowse link
G NGFR nerve growth factor receptor treatment ISO RGD PMID:23940017 RGD:10414074 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:11526986 RGD:10395358 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NPPB natriuretic peptide B IEP
EXP
associated with lung diseases;protein:increased expression:serum:
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:19803787 PMID:23837838 RGD:7247620 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NPY neuropeptide Y ISO protein:increased expression:adrenal medulla RGD PMID:23570732 RGD:10448961 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO mRNA:increased expression:lung
associated with Subarachnoid Hemorrhage
RGD PMID:18787991 PMID:20864352 RGD:5134971, RGD:11035222 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NT5E 5'-nucleotidase ecto ISO protein:altered expression:cerebral cortex (rat) RGD PMID:21337375 RGD:5134348 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791
JBrowse link
G P2RY1 purinergic receptor P2Y1 ISO protein:increased expression:brain, astrocyte RGD PMID:19115395 RGD:2315811 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439
JBrowse link
G PALLD palladin, cytoskeletal associated protein ISO protein:increased expression:brain, astrocyte RGD PMID:12932445 RGD:2325786 NCBI chr 4:168,497,039...168,928,441
Ensembl chr 4:168,497,052...168,928,457
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA,protein:increased expression:brain: RGD PMID:11421591 RGD:9835358 NCBI chr12:79,584,879...79,691,097
Ensembl chr12:79,574,979...79,690,964
JBrowse link
G PDE4D phosphodiesterase 4D ISO mRNA, protein:alternative form, decreased phosphorylation:brain RGD PMID:23057870 RGD:7327147 NCBI chr 5:58,969,038...60,524,329
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 7:497,245...520,668
Ensembl chr 7:497,258...520,296
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 4:54,229,127...54,298,245
Ensembl chr 4:54,229,280...54,298,245
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22658532 RGD:6484732 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr19:46,019,153...46,023,053
Ensembl chr19:46,019,153...46,023,053
JBrowse link
G PGR progesterone receptor ISO RGD PMID:23211561 RGD:7248711 NCBI chr11:101,029,624...101,130,681
Ensembl chr11:101,029,624...101,129,813
JBrowse link
G PHB prohibitin ISO protein:increased oxidation:cerebral cortex RGD PMID:17518533 RGD:2292409 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,052...49,414,901
JBrowse link
G PHB2 prohibitin 2 ISO RGD PMID:24566151 RGD:12903261 NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780
JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 ISO protein:decreased expression:brain, nucleus RGD PMID:21545521 RGD:8693413 NCBI chr15:68,054,315...68,193,847
Ensembl chr15:68,054,309...68,198,603
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO agonist more effective in combination with simvastatin (rat) RGD PMID:18562561 RGD:5508455 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha treatment ISO protein:decreased expression:frontal cortex (rat) RGD PMID:22642418 PMID:24345766 RGD:6484257, RGD:10059630 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO
EXP
protein: :hippocampus
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:14499481 PMID:19751097 RGD:6483311 NCBI chr 4:101,023,418...101,348,295
Ensembl chr 4:101,023,409...101,348,278
JBrowse link
G PRF1 perforin 1 IEP RGD PMID:20537642 RGD:6482807 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO protein:increased expression:striatum, microglia (rat) RGD PMID:15234107 RGD:9850280 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,808
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO
IEP
protein:increased expression:microglia, macrophage
protein:increased expression:microglial cells, macrophage, endothelial cell
RGD PMID:19719848 PMID:11565600 PMID:12005397 RGD:5688162, RGD:5688242, RGD:5688239 NCBI chr 9:122,369,906...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12410334 PMID:20810888 PMID:21549006 PMID:21866634 PMID:19719848 RGD:5508191, RGD:5688162 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:12088737 RGD:727637 NCBI chr 7:121,873,161...122,062,036
Ensembl chr 7:121,873,089...122,062,036
JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 ISO protein:increased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr 4:75,479,033...75,514,715
Ensembl chr 4:75,479,033...75,514,764
JBrowse link
G REG3A regenerating family member 3 alpha ISO mRNA:increased expression:cerebral cortex (rat) RGD PMID:19351265 RGD:9831399 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:ileum RGD PMID:18288455 RGD:2298787 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351
JBrowse link
G RHOA ras homolog family member A ISO protein:increased expression:microglial cell, brain RGD PMID:17929039 RGD:2298888 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998
JBrowse link
G ROBO2 roundabout guidance receptor 2 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 3:75,906,675...77,649,964
Ensembl chr 3:75,906,695...77,649,964
JBrowse link
G ROBO3 roundabout guidance receptor 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr11:124,865,432...124,881,471
Ensembl chr11:124,865,432...124,881,471
JBrowse link
G RPS27A ribosomal protein S27a ISO mRNA:decreased expression:cerebral cortex, hippocampus RGD PMID:17936732 RGD:11041870 NCBI chr 2:55,231,903...55,235,853
Ensembl chr 2:55,231,903...55,235,853
JBrowse link
G S100B S100 calcium binding protein B severity IEP
EXP
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:11520488 PMID:21783483 PMID:21976236 RGD:5508761 NCBI chr21:46,598,604...46,605,243
Ensembl chr21:46,598,604...46,605,208
JBrowse link
G SELE selectin E ISO protein:increased expression:brain RGD PMID:19107536 RGD:2313599 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
JBrowse link
G SERPINC1 serpin family C member 1 EXP CTD Direct Evidence: therapeutic CTD PMID:21534203 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327
JBrowse link
G SERPINF1 serpin family F member 1 treatment IMP
ISO
human gene in a rat model
protein:altered expression:cerebellum (rat)
RGD PMID:20142768 PMID:17709187 RGD:8612994, RGD:8622925 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
JBrowse link
G SIRT1 sirtuin 1 treatment ISO RGD PMID:17970622 RGD:9497541 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO protein:increased expression:brain RGD PMID:19852587 RGD:2315049 NCBI chr 5:36,152,067...36,184,319
Ensembl chr 5:36,151,989...36,196,849
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO protein:decreased expression:brain RGD PMID:18848922 RGD:5686682 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720
JBrowse link
G SLIT1 slit guidance ligand 1 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr10:96,998,038...97,185,959
Ensembl chr10:96,998,038...97,185,959
JBrowse link
G SLIT3 slit guidance ligand 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 5:168,661,740...169,301,139
Ensembl chr 5:168,661,733...169,301,139
JBrowse link
G SNCA synuclein alpha ISO RGD PMID:14637093 PMID:25089700 RGD:6480195, RGD:11576302 NCBI chr 4:89,724,099...89,838,324
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SNCB synuclein beta ISO RGD PMID:14637093 RGD:6480195 NCBI chr 5:176,620,082...176,630,556
Ensembl chr 5:176,620,082...176,630,556
JBrowse link
G SNCG synuclein gamma ISO RGD PMID:14637093 RGD:6480195 NCBI chr10:86,955,759...86,963,260
Ensembl chr10:86,958,599...86,963,258
JBrowse link
G SNW1 SNW domain containing 1 ISO mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22965216 RGD:11035237 NCBI chr14:77,717,599...77,761,156
Ensembl chr14:77,717,599...77,761,207
JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:16248885 RGD:1581214 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 ISO
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:24462953 PMID:16248885 RGD:1581214 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA:increased expression:brain, blood vessel RGD PMID:9704602 RGD:2300066 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G SSTR2 somatostatin receptor 2 ISO RGD PMID:11879809 RGD:2325002 NCBI chr17:73,165,010...73,176,633
Ensembl chr17:73,165,010...73,176,633
JBrowse link
G SSTR3 somatostatin receptor 3 ISO RGD PMID:11879809 RGD:2325002 NCBI chr22:37,204,237...37,220,451
Ensembl chr22:37,204,237...37,212,477
JBrowse link
G SSTR4 somatostatin receptor 4 ISO RGD PMID:11879809 RGD:2325002 NCBI chr20:23,035,312...23,039,237
Ensembl chr20:23,035,312...23,039,237
JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:21596098 RGD:6483023 NCBI chr 2:190,968,989...191,014,197
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:brain RGD PMID:21596098 PMID:22145815 PMID:22827467 RGD:6483023, RGD:8694312, RGD:6892706 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,540
JBrowse link
G STRN striatin ISO RGD PMID:16351572 RGD:2311293 NCBI chr 2:36,837,698...36,966,607
Ensembl chr 2:36,837,698...36,966,536
JBrowse link
G TARDBP TAR DNA binding protein IEP RGD PMID:22101322 RGD:5687195 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528
JBrowse link
G TF transferrin ISO RGD PMID:22538758 RGD:7244386 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
JBrowse link
G TH tyrosine hydroxylase ISO protein:decreased activity:striatum (rat) RGD PMID:21047500 RGD:5128822 NCBI chr11:2,163,929...2,174,081
Ensembl chr11:2,163,929...2,171,815
JBrowse link
G THBD thrombomodulin onset IEP RGD PMID:17895610 RGD:5685007 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO mRNA:increased expression:brain, astrocytes RGD PMID:10719361 RGD:2290468 NCBI chr  X:47,582,408...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO mRNA:increased expression:brain, neuron, microglial cell RGD PMID:10719361 RGD:2290468 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TJP1 tight junction protein 1 ISO RGD PMID:19889224 RGD:2325128 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
JBrowse link
G TLR1 toll like receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:38,791,055...38,806,262
Ensembl chr 4:38,790,677...38,856,817
JBrowse link
G TLR2 toll like receptor 2 ISO
EXP
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:18316784 RGD:2312713 NCBI chr 4:153,684,080...153,710,643
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G TLR4 toll like receptor 4 ISO
EXP
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:18316784 RGD:2312713 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TLR9 toll like receptor 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
JBrowse link
G TNF tumor necrosis factor EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19800810 PMID:21549006 PMID:10674461 RGD:13825262 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF13B TNF receptor superfamily member 13B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:16,939,081...16,972,118
Ensembl chr17:16,929,816...16,972,118
JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr22:41,922,032...41,926,806
Ensembl chr22:41,922,032...41,926,806
JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:2,556,371...2,563,829
Ensembl chr 1:2,555,639...2,565,382
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO
EXP
protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21549006 PMID:17074049 RGD:1624183 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TNFSF12 TNF superfamily member 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:7,549,058...7,557,881
Ensembl chr17:7,549,058...7,557,890
JBrowse link
G TRAF4 TNF receptor associated factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:28,744,004...28,750,956
Ensembl chr17:28,744,005...28,750,956
JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 ISO mRNA, protein:increased expression:cerebral cortex, hippocampus RGD PMID:20309649 RGD:9999437 NCBI chr21:44,350,112...44,442,807
Ensembl chr21:44,350,163...44,443,081
JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:17936732 RGD:11041870 NCBI chr19:18,563,766...18,577,550
Ensembl chr19:18,571,730...18,577,550
JBrowse link
G UCP2 uncoupling protein 2 IMP
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:12858170 PMID:12858170 RGD:7204436 NCBI chr11:73,974,671...73,983,202
Ensembl chr11:73,974,672...73,982,843
JBrowse link
G VEGFA vascular endothelial growth factor A ISO
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:18065154 PMID:12230324 RGD:1580574 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VEGFB vascular endothelial growth factor B ISO mRNA, protein:increased expression:brain RGD PMID:12230324 RGD:1580574 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264
JBrowse link
G VIM vimentin ISO protein:increased expression:brain RGD PMID:19728994 PMID:15527750 RGD:6480519, RGD:6480527 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
Brain Injuries, Diffuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S100B S100 calcium binding protein B EXP CTD Direct Evidence: marker/mechanism CTD PMID:30076900 NCBI chr21:46,598,604...46,605,243
Ensembl chr21:46,598,604...46,605,208
JBrowse link
Brain Injuries, Traumatic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 ISO RGD PMID:22489706 RGD:13703033 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791
JBrowse link
G APP amyloid beta precursor protein treatment IDA RGD PMID:29320530 RGD:13782048 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO RGD PMID:24582457 RGD:13782254 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G CAPN1 calpain 1 ISO protein:increased expression:cytosol, plasma membrane RGD PMID:9469158 RGD:13792664 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
JBrowse link
G CAPN2 calpain 2 ISO RGD PMID:9469158 RGD:13792664 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018
JBrowse link
G CD163 CD163 molecule ISO protein:increased expression:brain, macrophage (rat) RGD PMID:22583855 RGD:127285798 NCBI chr12:7,470,811...7,503,808
Ensembl chr12:7,470,811...7,503,893
JBrowse link
G CD8A CD8a molecule ISO mRNA:increased expression:brain (mouse) RGD PMID:31383034 RGD:124715446 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment ISO RGD PMID:26435412 RGD:27095897 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G DRD1 dopamine receptor D1 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G FUBP1 far upstream element binding protein 1 ISO RGD PMID:23797733 RGD:13673879 NCBI chr 1:77,944,055...77,979,435
Ensembl chr 1:77,944,055...77,979,110
JBrowse link
G GNAL G protein subunit alpha L ISO RGD PMID:29215295 RGD:13513923 NCBI chr18:11,689,015...11,885,685
Ensembl chr18:11,689,264...11,885,685
JBrowse link
G ICAM1 intercellular adhesion molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G ITGB1 integrin subunit beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G LAMA1 laminin subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO protein:increased expression:hippocampus: RGD PMID:28365875 RGD:13703062 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365
JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:31539545 RGD:126781751 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G MAPT microtubule associated protein tau treatment ISO RGD PMID:28412141 PMID:25771151 PMID:26484783 PMID:26729399 RGD:13800902, RGD:13800917, RGD:13800912, RGD:13800909 NCBI chr17:45,894,538...46,028,334
Ensembl chr17:45,894,527...46,028,334
JBrowse link
G MIR155 microRNA 155 ISO RGD PMID:28804446 RGD:25314324 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MMP9 matrix metallopeptidase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G NCSTN nicastrin ISO RGD PMID:18240300 RGD:13801189 NCBI chr 1:160,343,328...160,358,949
Ensembl chr 1:160,343,316...160,358,952
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:brain: RGD PMID:30855558 RGD:26884463 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 EXP CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 1:9,942,923...9,996,884
Ensembl chr 1:9,943,428...9,985,501
JBrowse link
G NOS2 nitric oxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G OCLN occludin EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15829224 PMID:28642177 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PDE10A phosphodiesterase 10A ISO RGD PMID:29215295 RGD:13513923 NCBI chr 6:165,327,287...165,988,115
Ensembl chr 6:165,327,287...165,988,078
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:20713027 RGD:13830881 NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:20713027 RGD:13830881 NCBI chr 9:101,591,604...101,594,969
Ensembl chr 9:101,591,604...101,595,021
JBrowse link
G PSEN1 presenilin 1 ISO RGD PMID:18240300 RGD:13801189 NCBI chr14:73,136,436...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 PMID:28642177 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:28433746 RGD:14995478 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 treatment ISO RGD PMID:27553877 RGD:14995939 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G UBE4B ubiquitination factor E4B EXP CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 1:10,032,958...10,181,239
Ensembl chr 1:10,032,832...10,181,239
JBrowse link
Bronchopulmonary Dysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO RGD PMID:26431790 RGD:11537057 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BID BH3 interacting domain death agonist ISO RGD PMID:26431790 RGD:11537057 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
JBrowse link
G CASP3 caspase 3 ISO RGD PMID:26431790 RGD:11537057 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 ISO RGD PMID:26431790 RGD:11537057 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 ISO RGD PMID:26431790 RGD:11537057 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase ISO RGD PMID:19693467 RGD:5130750 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL7 C-C motif chemokine ligand 7 ISO RGD PMID:16888287 RGD:5130981 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CD209 CD209 molecule IEP RGD PMID:20050784 RGD:5131185 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564
JBrowse link
G CHI3L1 chitinase 3 like 1 IEP protein:decreased secretion:lung, secretion (human) RGD PMID:20558631 RGD:4892651 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO RGD PMID:19951473 RGD:5134972 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G DAG1 dystroglycan 1 IAGP DNA:SNP: :p.N494H (human) RGD PMID:17196572 RGD:11537474 NCBI chr 3:49,468,703...49,535,618
Ensembl chr 3:49,468,703...49,535,618
JBrowse link
G EDN1 endothelin 1 ISO protein:increased expression:lung (rat) RGD PMID:20647310 RGD:4144841 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO RGD PMID:23065129 RGD:10395385 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IDA RGD PMID:22003089 RGD:10402122 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion, haplotype:: (human) RGD PMID:24120392 RGD:12792215 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP DNA:polymorphism:exon:p.I105V (human) RGD PMID:14726935 RGD:4142520 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion, haplotype:: (human) RGD PMID:24120392 RGD:12792215
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:23065129 PMID:26431790 RGD:10395385, RGD:11537057 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G IL1B interleukin 1 beta IEP
EXP
protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16813970 PMID:15539764 RGD:4143172 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility IEP
IAGP
protein:increased expression:lung
associated with Premature Birth;DNA:polymorphism::
RGD PMID:15539764 PMID:22882323 RGD:4143172, RGD:12910846 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP associated with Premature Birth;DNA:polymorphism:exon: RGD PMID:22882323 RGD:12910846 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MIF macrophage migration inhibitory factor IEP associated with Respiratory Distress Syndrome, Newborn; protein:increased expression:lung RGD PMID:18097062 RGD:4891007 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:19097983 RGD:5129685 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MUC1 mucin 1, cell surface associated severity IEP protein:increased expression:cord plasma RGD PMID:18025794 RGD:5131170 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G NFKBIA NFKB inhibitor alpha exacerbates IAGP DNA:SNPs:promoter: (rs2233406, rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,513...35,404,749
JBrowse link
G POSTN periostin EXP CTD Direct Evidence: marker/mechanism CTD PMID:22363622 NCBI chr13:37,562,585...37,598,839
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 IEP RGD PMID:11435254 RGD:5144211 NCBI chr11:62,419,033...62,423,195
Ensembl chr11:62,405,103...62,423,195
JBrowse link
G SERPINE1 serpin family E member 1 IEP associated with Premature Birth;protein:increased expression:blood: RGD PMID:25140773 RGD:13208551 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SFTPA1 surfactant protein A1 susceptibility IAGP DNA:snps, haplotypes:multiple (human)
DNA:polymorphisms, haplotype: (human)
RGD PMID:17264398 PMID:11105614 RGD:4143384, RGD:4144876 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455
JBrowse link
G SFTPB surfactant protein B susceptibility IAGP DNA:deletion:intron (human)
DNA:polymorphism:intron (human)
RGD PMID:15102713 PMID:12424586 PMID:17264398 RGD:4143405, RGD:4143418, RGD:4143384 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741
JBrowse link
G SFTPD surfactant protein D IAGP RGD PMID:17264398 RGD:4143384 NCBI chr10:79,937,740...79,982,236
Ensembl chr10:79,937,467...79,982,614
JBrowse link
G TNF tumor necrosis factor severity
no_association
IAGP DNA:SNP:promoter:-238A>G (human)
DNA:SNP:promoter:-308G>A (human)
RGD PMID:15286263 PMID:15286263 RGD:12904049, RGD:12904049 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 ISO RGD PMID:26431790 RGD:11537057 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TXN thioredoxin EXP CTD Direct Evidence: therapeutic CTD PMID:20812253 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G VDR vitamin D receptor susceptibility IAGP associated with Premature Birth;DNA:SNPs: :rs2228570,rs731236(human) RGD PMID:24796371 RGD:13432055 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin ISO RGD PMID:14960360 RGD:1598513 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G ALB albumin disease_progression IEP RGD PMID:23917657 RGD:11036092 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G BAD BCL2 associated agonist of cell death ISO protein:increased expression:neutrophil RGD PMID:15625305 RGD:2292697 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:22153006 RGD:10054126 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:22153006 RGD:10054126 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:24730400 RGD:11561936 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:22153006 RGD:10054126 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CCNC cyclin C ISO protein:increased expression:skin RGD PMID:16271231 RGD:2315993 NCBI chr 6:99,542,387...99,568,814
Ensembl chr 6:99,542,387...99,568,825
JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:17996899 RGD:2289134 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CD14 CD14 molecule ISO mRNA:increased expression:multiple organs: RGD PMID:11829837 PMID:12435950 RGD:7204443, RGD:2313390 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,701
JBrowse link
G CD86 CD86 molecule ISO protein:increased expression:spleen, dendritic cell (rat) RGD PMID:20233162 RGD:4892209 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CLDN1 claudin 1 ISO associated with Binge Drinking;protein: decreased tyrosine phosphorylation:intestine mucosa" RGD PMID:22001439 RGD:8655996 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
JBrowse link
G CPB2 carboxypeptidase B2 ISO protein:increased activity:plasma RGD PMID:15497025 RGD:2313648 NCBI chr13:46,053,066...46,105,033
Ensembl chr13:46,053,186...46,105,033
JBrowse link
G CRP C-reactive protein ISO RGD PMID:20664819 RGD:5131457 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 ISO protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO protein:decreased expression:heart,mitochondrion: RGD PMID:23041468 RGD:10401126 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,489,308...73,525,587
JBrowse link
G FGA fibrinogen alpha chain ISO protein:increased expression:plasma (rat) RGD PMID:20664819 RGD:5131457 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,128...154,590,745
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO protein:increased expression:epidermis: RGD PMID:9204964 RGD:10402083 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO protein:decreased phosphorylation, decreased activity:T cell (rat) RGD PMID:12353920 RGD:2324864 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO mRNA:increased expression:heart left ventricle (rat) RGD PMID:29232706 RGD:13506829 NCBI chr11:67,266,420...67,286,556
Ensembl chr11:67,266,473...67,286,556
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO protein:increased activity,altered phosphorylation:skeletal muscle: RGD PMID:17686886 RGD:10045647 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSTA4 glutathione S-transferase alpha 4 IEP
ISO
mRNA:altered expression:fat, muscle, skin (human)
mRNA:decreased expression:gastrocnemius muscle (mouse)
RGD PMID:22038048 PMID:22038048 RGD:5687774, RGD:5687774 NCBI chr 6:52,977,952...52,995,332
Ensembl chr 6:52,977,948...52,995,304
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:Peyer's patches (rat) RGD PMID:19439119 RGD:9068477 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:20723408 RGD:10402183 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G IGF1 insulin like growth factor 1 ISO mRNA:altered expression:multiple RGD PMID:10827012 RGD:12910869 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:decreased expression:skeletal muscle: RGD PMID:25186839 RGD:10046020 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO mRNA:decreased expression:liver RGD PMID:10827012 RGD:12910869 NCBI chr16:1,790,413...1,794,908
Ensembl chr16:1,790,413...1,794,971
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO mRNA:increased expression:kidney, liver RGD PMID:10827012 RGD:12910869 NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO mRNA:altered expression:kidney, liver, muscle RGD PMID:10827012 RGD:12910869 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO mRNA:increased expression:liver RGD PMID:11742840 RGD:1626551 NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385
JBrowse link
G IL10 interleukin 10 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18277951 PMID:22341647 RGD:11049470 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL18 interleukin 18 ISO protein:decreased expression:liver RGD PMID:19197224 RGD:4889576 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:10431976 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:18277951 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10431976 PMID:18277951 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G LBP lipopolysaccharide binding protein ISO RGD PMID:12435950 RGD:2313390 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:24730400 RGD:11561936 NCBI chr20:34,546,823...34,560,345
Ensembl chr20:34,546,854...34,560,345
JBrowse link
G MIF macrophage migration inhibitory factor ISO mRNA, protein:increased expression:liver, serum RGD PMID:14625478 RGD:1642001 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO mRNA:increased expression:ileum RGD PMID:15182445 RGD:9685358 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO mRNA, protein:increased expression:brain RGD PMID:17156757 RGD:1642051 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase ISO
EXP
protein:increased activity:kidney, lung
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11996850 PMID:22356815 RGD:6909170 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MSTN myostatin ISO mRNA:increased expression:skeletal muscle RGD PMID:11481237 RGD:2303598 NCBI chr 2:190,055,700...190,062,729
Ensembl chr 2:190,055,700...190,062,729
JBrowse link
G MT-CYB mitochondrially encoded cytochrome b IDA RGD PMID:3779466 RGD:2298976 NCBI chr MT:14,747...15,887
Ensembl chr MT:14,747...15,887
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO protein:increased serine phosphorylation:skeletal muscle RGD PMID:20594757 RGD:10041043 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO protein:increased expression:neutrophil RGD PMID:9329126 RGD:2314453 NCBI chr 1:183,555,562...183,590,914
Ensembl chr 1:183,555,562...183,590,876
JBrowse link
G NGF nerve growth factor ISO RGD PMID:12133564 RGD:5144074 NCBI chr 1:115,285,915...115,338,253
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NOS2 nitric oxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15650120 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment ISO protein:decreased activity:liver, lung, kidney RGD PMID:19216853 PMID:11990926 RGD:4892319, RGD:7174720 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G OCLN occludin ISO associated with Binge Drinking;protein:decreased expression, decreased tyrosine, threonine phosphorylation:intestine mucosa: RGD PMID:22001439 RGD:8655996 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 ISO protein:increased expression:ileum (rat) RGD PMID:15449568 RGD:2326198 NCBI chr 5:41,730,065...41,870,535
Ensembl chr 5:41,730,065...41,870,425
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:17826914 RGD:2304127 NCBI chr20:3,068,871...3,072,517
Ensembl chr20:3,071,620...3,072,517
JBrowse link
G PDCD1 programmed cell death 1 treatment ISO associated with Pseudomonas Infections; associated with Staphylococcal Infections RGD PMID:29345058 RGD:41410788 NCBI chr 2:241,849,881...241,858,908
Ensembl chr 2:241,849,884...241,858,894
JBrowse link
G PDE4B phosphodiesterase 4B ISO mRNA:increased expression:extensor digitorum longus muscle RGD PMID:29693432 RGD:13782127 NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579
JBrowse link
G PKLR pyruvate kinase L/R ISO RGD PMID:12417155 RGD:1625591 NCBI chr 1:155,289,293...155,301,438
Ensembl chr 1:155,289,293...155,301,438
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO protein:increased expression:heart RGD PMID:17483741 RGD:1642444 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
JBrowse link
G PLAT plasminogen activator, tissue type IEP protein:increased expression:plasma (human) RGD PMID:11525850 RGD:11541048 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G POMC proopiomelanocortin EXP CTD Direct Evidence: marker/mechanism CTD PMID:2968671 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PRKCD protein kinase C delta ISO protein:altered localization:cardiac muscle cell RGD PMID:16990486 RGD:1642547 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15650120 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 treatment ISO RGD PMID:24973766 RGD:9850087 NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 treatment ISO RGD PMID:24973766 RGD:9850087 NCBI chr 2:172,735,282...173,052,893
Ensembl chr 2:172,735,274...173,052,893
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO protein:decreased phosphorylation:heart RGD PMID:14695116 RGD:1643025 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
JBrowse link
G SERPINA1 serpin family A member 1 ISO protein:increased expression:serum RGD PMID:12509927 RGD:1643164 NCBI chr14:94,376,747...94,390,654
Ensembl chr14:94,376,747...94,390,693
JBrowse link
G SERPING1 serpin family G member 1 treatment IDA RGD PMID:22447201 RGD:6903314 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171
JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO RGD PMID:17711618 RGD:4889516 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA, protein:increased expression:hepatocyte RGD PMID:12392283 RGD:730264 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
JBrowse link
G TAC1 tachykinin precursor 1 ISO protein:increased expression:plasma, lung RGD PMID:19797759 RGD:5147812 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:lung RGD PMID:18523300 RGD:5147819 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
JBrowse link
G TFPI tissue factor pathway inhibitor ISO protein:decreased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr 2:187,464,230...187,554,501
Ensembl chr 2:187,464,230...187,565,760
JBrowse link
G TNF tumor necrosis factor treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18277951 PMID:26152211 RGD:11049530 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO mRNA, protein:increased expression:thymus RGD PMID:18019056 RGD:2290498 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b ISO mRNA, protein:increased expression:thymus RGD PMID:18019056 RGD:2290498 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
JBrowse link
G UCN urocortin ISO RGD PMID:16125201 RGD:1642782 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445
JBrowse link
G VDAC2 voltage dependent anion channel 2 ISO RGD PMID:23863682 RGD:10003047 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448
JBrowse link
Burns, Chemical term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type EXP CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr17:6,993,791...7,010,754
Ensembl chr17:6,996,049...7,010,754
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G IL1A interleukin 1 alpha EXP