Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Wounds and Injuries
go back to main search page
Accession:DOID:9001600 term browser browse the term
Definition:Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.
Synonyms:exact_synonym: Injuries;   Injuries, Wounds;   Injury;   Injury and Wounds;   Research Related Injuries;   Research-Related Injury;   Trauma;   Traumas;   Wound;   Wounds;   Wounds, Injury
 primary_id: MESH:D014947;   RDO:0004686
 subset: RGD_JBrowse_slim
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
Wounds and Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:15708862 RGD:5509615 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669
JBrowse link
G ANKRD1 ankyrin repeat domain 1 ISO mRNA, protein:increased expression:multiple RGD PMID:15632022 RGD:5133280 NCBI chr10:87,652,254...87,661,173
Ensembl chr10:91,180,034...91,188,165
JBrowse link
G ARG1 arginase 1 ISO protein:increased expression:wound, fibroblast (rat) RGD PMID:12069499 RGD:634666 NCBI chr 6:129,372,747...129,383,880
Ensembl chr 6:133,479,966...133,491,162
JBrowse link
G CALCA calcitonin related polypeptide alpha ISO CTD Direct Evidence: therapeutic CTD PMID:18430544 NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO mRNA, protein:increased expression:ligament RGD PMID:19327017 RGD:2306564 NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 4:50,092,989...50,095,541
Ensembl chr 4:55,925,562...55,986,555
JBrowse link
G DCN decorin ISO RGD PMID:19393425 RGD:2311417 NCBI chr12:88,678,791...88,715,677
Ensembl chr12:91,994,129...92,031,413
JBrowse link
G EGF epidermal growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:21967610 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460
JBrowse link
G ENG endoglin disease_progression ISO RGD PMID:23349951 RGD:7248769 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641
JBrowse link
G FGF2 fibroblast growth factor 2 treatment ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
protein:increased expression:skin
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:11842932 PMID:12533868 PMID:16008728 PMID:21402405 PMID:23603001 RGD:2292211 RGD:2315863 RGD:8655580 RGD:8655582 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G GC GC vitamin D binding protein treatment ISO associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17852808 PMID:24263389 RGD:11041807 NCBI chr 4:52,431,196...52,473,762
Ensembl chr 4:58,729,236...58,792,073
JBrowse link
G HGF hepatocyte growth factor treatment ISO RGD PMID:16572191 RGD:8548635 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12649161 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G IGF1 insulin like growth factor 1 ISO associated with Rhinosinusitis; mRNA:increased expression:nose:
protein:increased expression:skin:
RGD PMID:20713758 PMID:21296499 RGD:8548883 RGD:8549452 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IL10 interleukin 10 ISO RGD PMID:14715528 RGD:1598466 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL1A interleukin 1 alpha ISO RGD PMID:18638276 RGD:2311088 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G LAMA3 laminin subunit alpha 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr18:16,941,316...17,208,363
Ensembl chr18:20,565,649...20,831,957
JBrowse link
G LAMB3 laminin subunit beta 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr 1:185,191,401...185,245,154
Ensembl chr 1:189,996,639...190,034,206
JBrowse link
G LAMC2 laminin subunit gamma 2 ISO CTD Direct Evidence: therapeutic CTD PMID:15541073 NCBI chr 1:158,697,084...158,763,209
Ensembl chr 1:162,862,785...162,921,864
JBrowse link
G LTF lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chr 3:46,337,738...46,367,476
Ensembl chr 3:47,442,440...47,471,532
JBrowse link
G LUM lumican ISO CTD Direct Evidence: therapeutic CTD PMID:24367547 NCBI chr12:88,636,825...88,644,665
Ensembl chr12:91,952,277...91,960,388
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO RGD PMID:9888422 RGD:9685353 NCBI chr11:97,467,037...97,477,305
Ensembl chr11:100,960,032...100,971,099
JBrowse link
G MMP8 matrix metallopeptidase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11172683 NCBI chr11:97,650,408...97,663,731
Ensembl chr11:101,143,268...101,156,736
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO protein:decreased expression:hypothalamus: RGD PMID:11931711 RGD:9835019 Ensembl chr20:62,004,176...62,017,866 JBrowse link
G OPTN optineurin ISO RGD PMID:16109995 RGD:7775038 NCBI chr10:13,104,335...13,142,725
Ensembl chr10:13,077,345...13,115,773
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO RGD PMID:18205704 RGD:2292158 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B treatment ISO protein:increased expression:skin RGD PMID:3280728 PMID:12533868 RGD:10449501 RGD:2292211 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO protein:increased expression:skin RGD PMID:12533868 RGD:2292211 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
G PLAT plasminogen activator, tissue type ISO protein:increased expression:plasma (rat) RGD PMID:25423126 RGD:11541076 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779
JBrowse link
G PNOC prepronociceptin ISO protein:decreased expression:hypothalamus: RGD PMID:11931711 RGD:9835019 NCBI chr 8:27,596,413...27,622,844
Ensembl chr 8:24,796,638...24,822,758
JBrowse link
G POSTN periostin ISO protein:increased expression:skin: RGD PMID:22681660 RGD:10040991 NCBI chr13:18,779,297...18,815,207
Ensembl chr13:37,368,030...37,407,212
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA, protein:increased expression:skin, fibroblast RGD PMID:8245406 RGD:2300076 NCBI chr 5:147,087,903...147,112,466
Ensembl chr 5:153,090,181...153,115,750
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:9525990 NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO protein:increased expression:skin RGD PMID:12533868 PMID:17117936 RGD:2292211 RGD:2302090 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:17117936 PMID:18205704 RGD:2292158 RGD:2302090 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD PMID:18205704 RGD:2292158 NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO mRNA, protein:increased expression:dorsal root ganglion RGD PMID:16683235 RGD:1600154 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419
JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 ISO mRNA, protein:increased expression:carotid artery RGD PMID:10082471 RGD:2290470 NCBI chr 3:12,079,195...12,087,485
Ensembl chr 3:12,425,429...12,433,192
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21192278 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO RGD PMID:23603001 RGD:8655580 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
Acute Heart Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MFN1 mitofusin 1 ISO mRNA, protein:increased expression:heart (rat) RGD PMID:25677476 RGD:12437078 NCBI chr 3:176,378,175...176,423,943
Ensembl chr 3:184,552,108...184,596,763
JBrowse link
Acute Lung Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment ISO associated wit Escherichia coli Infections RGD PMID:29990483 RGD:40400897 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853
JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment
severity
ISO human protein in a mouse model
CTD Direct Evidence: therapeutic
associated with avian influenza;protein:decreased expression:lung (mouse)
associated with Escherichia coli Infections
RGD
CTD
PMID:16001071 PMID:25391767 PMID:27302421 PMID:29990483 RGD:32716389 RGD:40400897 RGD:40818412 NCBI chr  X:8,189,267...8,229,415
Ensembl chr  X:15,470,896...15,510,891
JBrowse link
G ACVR1 activin A receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297076 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
JBrowse link
G ADAR adenosine deaminase RNA specific treatment ISO RGD PMID:18520702 RGD:10755331 NCBI chr 1:129,937,993...129,983,747 JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing treatment ISO associated with Sepsis RGD PMID:22156343 PMID:23522481 RGD:5686380 RGD:8695940 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G ADRA2A adrenoceptor alpha 2A ISO RGD PMID:21542970 RGD:6480481 NCBI chr10:107,669,860...107,673,685 JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO associated with Hyperoxia; protein:decreased expression:bronchoalveolar lavage fluid (rat) RGD PMID:23576805 RGD:7244254 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G AKAP12 A-kinase anchoring protein 12 ISO mRNA,protein:increased expression:lung RGD PMID:23912647 RGD:14348970 NCBI chr 6:149,058,350...149,176,710
Ensembl chr 6:153,757,081...153,873,925
JBrowse link
G AKT1 AKT serine/threonine kinase 1 severity ISO RGD PMID:23904165 RGD:38676478 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G ALB albumin ISO RGD PMID:22592748 RGD:6483494 NCBI chr 4:50,773,244...50,790,474
Ensembl chr 4:56,605,322...56,622,418
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:19752233 RGD:5509626 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669
JBrowse link
G APOA1 apolipoprotein A1 ISO CTD Direct Evidence: therapeutic CTD PMID:20972769 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122
JBrowse link
G AQP5 aquaporin 5 ISO associated with Disseminated Intravascular Coagulation;mRNA,protein:decreased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr12:38,789,505...38,793,305
Ensembl chr12:39,684,008...39,687,127
JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20554700 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G C3 complement C3 treatment ISO RGD PMID:22763771 RGD:11040808 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G CASP3 caspase 3 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:29755641 PMID:32062619 RGD:13782288 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:29755641 RGD:13782288 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CAT catalase ISO CTD Direct Evidence: therapeutic CTD PMID:15612528 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G CAV1 caveolin 1 treatment ISO RGD PMID:24919947 RGD:10045573 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO mRNA, protein:increased expression:lung RGD PMID:21767135 RGD:6480432 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO associated with Pancreatitis RGD PMID:17312463 RGD:5688151 NCBI chr 3:46,107,526...46,114,229
Ensembl chr 3:47,214,688...47,215,755
JBrowse link
G CD36 CD36 molecule ISO associated with Malaria RGD PMID:18483551 RGD:6893505 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO associated with Sepsis;mRNA:increased expression:lung RGD PMID:10069420 RGD:5135253 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO associated with Sepsis;mRNA:increased expression:lung
mRNA, protein:increased expression:lung
protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10069420 PMID:15557650 PMID:19106808 PMID:27525872 RGD:5135247 RGD:5135253 RGD:5147925 NCBI chr 4:50,092,989...50,095,541
Ensembl chr 4:55,925,562...55,986,555
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO associated with Reperfusion Injury
mRNA, protein:increased expression:lung
RGD PMID:7814607 PMID:15557650 RGD:5135247 RGD:5135256 NCBI chr 4:50,357,643...50,359,822
Ensembl chr 4:56,189,961...56,192,402
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 disease_progression ISO associated with sepsis;protein:increased expression:blood serum (human) RGD PMID:28506137 RGD:40925937 NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 treatment ISO associated with Pancreatitis RGD PMID:17014919 RGD:7257703 NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA:increased expression:lung RGD PMID:16882535 PMID:18367723 RGD:5135235 RGD:5147744 NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636
JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 treatment ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr  X:67,412,410...67,469,366
Ensembl chr  X:77,524,455...77,525,468
JBrowse link
G DDIT3 DNA damage inducible transcript 3 treatment ISO associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G EDN1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16625121 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:20935109 RGD:5131862 NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615
JBrowse link
G ELANE elastase, neutrophil expressed treatment ISO associated with Shock, Hemorrhagic;
protein:increased expression:perfusate:
RGD PMID:15257085 PMID:17203197 PMID:18283562 RGD:10450548 RGD:10450585 RGD:10450587 NCBI chr19:276,499...280,598 JBrowse link
G EPHX1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26840748 NCBI chr 1:201,271,366...201,306,635
Ensembl chr 1:206,272,866...206,307,581
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:22051199 RGD:5688354 NCBI chr 8:26,761,090...26,818,436
Ensembl chr 8:23,964,094...24,017,749
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 treatment ISO associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:22804886 RGD:7387313 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased expression: respiratory system fluid/secretion RGD PMID:21964405 RGD:11341740 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050
JBrowse link
G FADD Fas associated via death domain treatment ISO associated with Shock, Hemorrhagic RGD PMID:24122010 RGD:11341811 NCBI chr11:65,300,889...65,305,020 JBrowse link
G FAS Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia ISO RGD PMID:19106808 RGD:5147925 NCBI chr 1:125,127,073...125,136,911
Ensembl chr 1:128,805,484...128,814,220
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa ISO RGD PMID:19106808 RGD:5147925 NCBI chr 1:136,892,311...136,906,450 JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb treatment ISO RGD PMID:19106808 RGD:5147925 NCBI chr 1:137,074,342...137,090,962 JBrowse link
G FGA fibrinogen alpha chain ISO protein:increased expression:blood (rat) RGD PMID:22804886 RGD:7387313 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO associated with Endotoxemia RGD PMID:21528367 RGD:5684427 NCBI chr13:9,584,850...9,779,542 JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO RGD PMID:23576849 RGD:8662452 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO protein:decreased expression:lung (rat) RGD PMID:25581610 RGD:13504847 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GSR glutathione-disulfide reductase ISO RGD PMID:7896613 RGD:7257562 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557
JBrowse link
G GZMB granzyme B ISO RGD PMID:20018616 RGD:5135517 NCBI chr14:5,399,888...5,403,200
Ensembl chr14:23,523,619...23,526,931
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO associated with Endotoxemia
associated with Crush Injuries
associated with Burns
RGD PMID:19766246 PMID:23874764 PMID:30465396 RGD:10402098 RGD:34901874 RGD:4892587 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:16922808 RGD:5508470 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785
JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO associated with Reperfusion Injury RGD PMID:20360627 PMID:20850789 RGD:4140418 RGD:4145326 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C ISO protein:altered localization:lung (mouse) RGD PMID:19029002 RGD:10054390 NCBI chr14:2,022,280...2,083,215 JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 treatment ISO associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17973899 PMID:20569121 PMID:27525872 RGD:8547719 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 treatment ISO RGD PMID:25278421 RGD:39939031 NCBI chr 8:39,108,310...39,123,611
Ensembl chr 8:36,617,312...36,632,352
JBrowse link
G IFNG interferon gamma ISO RGD PMID:21767135 RGD:6480432 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IL10 interleukin 10 no_association
treatment
ISO associated with Reperfusion Injury;protein:increased expression:lung, plasma
DNA:SNP:promoter:rs3021097 (human)
DNA:SNP:promoter:-1082G>A (rs1800896) (human)
RGD PMID:23801594 PMID:23902576 PMID:30412745 RGD:14975158 RGD:7364984 RGD:7365008 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL13 interleukin 13 ISO mRNA:increased expression:lung RGD PMID:15461830 RGD:4145512 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548
JBrowse link
G IL17A interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28600744 NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074
JBrowse link
G IL18 interleukin 18 treatment ISO associated with Myocardial Reperfusion Injury RGD PMID:24223666 RGD:8655952 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
mRNA, protein:increased expression:lung
RGD
CTD
PMID:8613550 PMID:20153312 PMID:20663306 PMID:21767135 PMID:22982561 More... RGD:4142531 RGD:4142807 RGD:4143193 RGD:6480432 RGD:7204498 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL2 interleukin 2 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:21767135 RGD:6480432 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4 interleukin 4 treatment ISO RGD PMID:24681349 RGD:10402798 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:bronchoalveolar lavage, blood, lung (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19995278 PMID:32062619 RGD:11062103 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO mRNA, protein:increased expression:lung (mouse) RGD PMID:21577093 RGD:36049795 NCBI chr12:22,661,613...22,721,203
Ensembl chr12:23,168,346...23,227,148
JBrowse link
G ITGB2 integrin subunit beta 2 ISO RGD PMID:1374449 RGD:6482199 NCBI chr21:31,181,228...31,216,033
Ensembl chr21:44,470,999...44,505,963
JBrowse link
G JAK3 Janus kinase 3 ISO RGD PMID:22359619 RGD:11531100 NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964
JBrowse link
G KDR kinase insert domain receptor ISO associated with Endotoxemia;mRNA, protein:decreased expression:lung RGD PMID:21528367 RGD:5684427 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G LOC100986475 metallothionein-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16166738 NCBI chr16:36,894,853...36,895,826
Ensembl chr16:56,007,922...56,028,093
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein ISO mRNA:increased expression:lung RGD PMID:8613550 PMID:15970097 RGD:4143168 RGD:4143193 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G LTB4R2 leukotriene B4 receptor 2 severity ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr14:5,081,509...5,088,761 JBrowse link
G MFN1 mitofusin 1 ISO mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 3:176,378,175...176,423,943
Ensembl chr 3:184,552,108...184,596,763
JBrowse link
G MFN2 mitofusin 2 ISO mRNA, protein:increased expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO RGD PMID:23040778 RGD:13207316 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO associated with Sepsis RGD PMID:21567117 RGD:9685338 NCBI chr11:97,467,037...97,477,305
Ensembl chr11:100,960,032...100,971,099
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:23040778 RGD:13207316 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MPO myeloperoxidase ISO associated with Kidney Reperfusion Injury; protein:increased activity:lung RGD PMID:22092133 RGD:6909173 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G MYLK myosin light chain kinase ISO associated with Sepsis
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16399953 PMID:19374788 RGD:1581052 NCBI chr 3:120,711,705...120,983,432
Ensembl chr 3:127,614,173...127,793,261
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24812154 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G NGF nerve growth factor ISO RGD PMID:17673270 RGD:5144065 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NLRP3 NLR family pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33012731 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 treatment ISO associated with Sepsis RGD PMID:22575870 RGD:8547530 NCBI chr16:30,955,976...30,995,451
Ensembl chr16:49,837,891...49,873,773
JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:16882535 RGD:5147744 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G NPPA natriuretic peptide A ISO RGD PMID:23422200 RGD:7247713 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:24669282 PMID:28065220 RGD:11035223 RGD:13442501 NCBI chr16:50,090,696...50,106,495
Ensembl chr16:69,470,288...69,489,731
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 3:190,890,242...190,995,133
Ensembl chr 3:201,207,607...201,312,358
JBrowse link
G P2RY12 purinergic receptor P2Y12 ISO associated with Shock, Hemorrhagic RGD PMID:21841533 RGD:6480522 NCBI chr 3:148,364,151...148,412,231 JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO DNA:hypermethylation RGD PMID:23546543 RGD:11533951 NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO associated with Pancreatitis, Experimental, Acute RGD PMID:16127429 RGD:11075069 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA,protein:increased expression:lung,blood vessel: RGD PMID:17136598 RGD:9835397 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22592748 RGD:6483494 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO associated with Endotoxemia;mRNA, protein:increased expression:lung (mouse) RGD PMID:31167111 RGD:41410778 NCBI chr10:6,185,415...6,294,641
Ensembl chr10:6,167,841...6,275,940
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO associated with endotoxemia RGD PMID:11714830 PMID:22198681 RGD:38599213 RGD:6482677 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614
JBrowse link
G PLA2G2A phospholipase A2 group IIA severity ISO RGD PMID:19235614 RGD:6482722 NCBI chr 1:18,930,294...18,934,563
Ensembl chr 1:19,971,084...19,977,627
JBrowse link
G PLAU plasminogen activator, urokinase treatment ISO associated with Endotoxemia RGD PMID:21473829 PMID:23324284 RGD:5147760 RGD:7241552 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO protein:decreased expression:lung (rat)
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:16083301 PMID:21153920 RGD:8553030 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PRDM1 PR/SET domain 1 ISO CTD Direct Evidence: therapeutic CTD PMID:33109608 NCBI chr 6:103,899,410...103,923,389
Ensembl chr 6:107,773,229...107,796,815
JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:21595935 RGD:6484539 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment ISO associated with Pseudomonas Infections
associated with Intestinal Reperfusion Injury
RGD PMID:16553944 PMID:18367148 RGD:11100043 RGD:11250405 NCBI chr2B:32,846,899...32,859,060
Ensembl chr2B:128,083,794...128,094,625
JBrowse link
G PROCR protein C receptor treatment ISO RGD PMID:20095324 RGD:13515130 NCBI chr20:31,500,838...31,543,928
Ensembl chr20:32,622,876...32,628,320
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:lung RGD PMID:19567182 PMID:20926798 RGD:5135287 RGD:5135496 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO protein:decreased expression:lung RGD PMID:16226776 PMID:18420837 RGD:5143982 RGD:5144142 NCBI chr11:57,774,560...57,780,334
Ensembl chr11:61,133,649...61,137,873
JBrowse link
G SERPINC1 serpin family C member 1 treatment ISO associated with Endotoxemia RGD PMID:17940748 RGD:11035256 NCBI chr 1:149,421,737...149,435,301
Ensembl chr 1:153,126,031...153,139,369
JBrowse link
G SERPINE1 serpin family E member 1 treatment ISO associated with Sepsis
associated with Shock, Hemorrhagic;mRNA:increased expression:lung (rat)
RGD PMID:10745022 PMID:18182560 PMID:25934465 RGD:11075078 RGD:11080962 RGD:11080967 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450
JBrowse link
G SERPING1 serpin family G member 1 treatment ISO RGD PMID:11685347 RGD:8661650 NCBI chr11:52,838,502...52,855,781
Ensembl chr11:56,309,686...56,326,639
JBrowse link
G SFTPA1 surfactant protein A1 ISO mRNA, protein:increased expression:pneumocyte RGD PMID:8569184 RGD:4143451 NCBI chr10:76,571,312...76,575,820 JBrowse link
G SFTPD surfactant protein D ISO CTD Direct Evidence: therapeutic CTD PMID:30060251 NCBI chr10:76,275,147...76,318,952
Ensembl chr10:78,965,252...78,974,181
JBrowse link
G SLPI secretory leukocyte peptidase inhibitor treatment
severity
ISO associated with Endotoxemia RGD PMID:10092827 PMID:25466948 RGD:9999422 RGD:9999425 NCBI chr20:41,583,429...41,585,773
Ensembl chr20:42,673,417...42,675,773
JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:19797759 RGD:5147812 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:lung RGD PMID:18523300 RGD:5147819 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018
JBrowse link
G TFF2 trefoil factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19880587 NCBI chr21:28,653,077...28,657,709
Ensembl chr21:41,973,111...41,977,227
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16100012 PMID:25278421 RGD:39939031 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G THBD thrombomodulin treatment ISO associated with Endotoxemia RGD PMID:19342415 PMID:19536047 PMID:20095324 RGD:13515130 RGD:5131887 RGD:5685372 NCBI chr20:22,992,341...22,996,415
Ensembl chr20:23,345,917...23,347,812
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 severity ISO RGD PMID:10092827 RGD:9999422 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:19567182 RGD:5135496 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
G TNF tumor necrosis factor no_association
treatment
ISO protein:increased expression:respiratory system fluid/secretion
mRNA, protein:increased expression:lung
DNA:SNP:promoter:rs1799964 (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
associated with Liver Reperfusion Injury
RGD PMID:11129814 PMID:19106808 PMID:21767135 PMID:30412745 RGD:14975158 RGD:14995473 RGD:5147925 RGD:6480432 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 ISO CTD Direct Evidence: therapeutic CTD PMID:26313688 NCBI chr2B:38,669,652...38,692,037
Ensembl chr2B:155,933,842...155,956,382
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 exacerbates
ameliorates
ISO RGD PMID:26832696 RGD:127284840 NCBI chr 6:40,861,283...40,874,446
Ensembl chr 6:42,163,337...42,183,091
JBrowse link
G TXN thioredoxin ISO CTD Direct Evidence: therapeutic CTD PMID:16298680 NCBI chr 9:81,399,056...81,411,607
Ensembl chr 9:109,565,557...109,578,311
JBrowse link
G VEGFA vascular endothelial growth factor A ISO associated with Endotoxemia;mRNA, protein:altered expression:lung, plasma RGD PMID:21528367 RGD:5684427 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
G VIP vasoactive intestinal peptide ISO CTD Direct Evidence: therapeutic
associated with Endotoxemia
CTD
RGD
PMID:8643465 PMID:20441697 RGD:4145303 NCBI chr 6:150,564,545...150,573,582
Ensembl chr 6:155,254,652...155,263,730
JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:9655743 RGD:13209002 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A severity ISO associated with toxic shock syndrome RGD PMID:23422584 RGD:39938961 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556
JBrowse link
anthracosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr 1:135,504,929...135,540,651
Ensembl chr 1:139,426,556...139,462,393
JBrowse link
G FLACC1 flagellum associated containing coiled-coil domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr2B:88,541,496...88,618,269
Ensembl chr2B:206,697,119...206,766,071
JBrowse link
G IL1A interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G RBM26 RNA binding motif protein 26 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr13:60,547,197...60,642,551
Ensembl chr13:79,585,632...79,670,999
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
Anthracycline-induced Cardiotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility ISO DNA:missense mutation:cds:p.G671V (human) RGD PMID:16330681 RGD:11041175 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238
JBrowse link
G CAPN2 calpain 2 treatment ISO RGD PMID:25634181 RGD:13792617 NCBI chr 1:199,335,582...199,399,267
Ensembl chr 1:204,335,573...204,409,150
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO associated with Leukemia, Myeloid, Acute;DNA:SNP:exon:p.K751Q (rs13181) (human) RGD PMID:24284041 RGD:11252190 NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819
JBrowse link
Aortic Rupture term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:2346371 PMID:25449986 NCBI chr  X:67,093,675...67,231,318
Ensembl chr  X:77,255,312...77,342,756
JBrowse link
G EDN2 endothelin 2 ISO RGD PMID:11947982 RGD:1580915 NCBI chr 1:40,777,582...40,783,410
Ensembl chr 1:42,092,811...42,098,721
JBrowse link
G FBN1 fibrillin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18178469 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G NPR1 natriuretic peptide receptor 1 ISO associated with Hypertension RGD PMID:9405681 RGD:737701 NCBI chr 1:129,034,972...129,050,439
Ensembl chr 1:132,664,948...132,679,327
JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16549638 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897
JBrowse link
asbestosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26699812 NCBI chr 6:129,372,747...129,383,880
Ensembl chr 6:133,479,966...133,491,162
JBrowse link
G ATF6 activating transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 1:137,178,629...137,382,256
Ensembl chr 1:140,977,750...141,176,725
JBrowse link
G CLCA1 chloride channel accessory 1 ISO mRNA, protein:increased expression:lung RGD PMID:17637221 RGD:4145655 NCBI chr 1:118,999,099...119,030,839
Ensembl chr 1:87,852,599...87,884,751
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO mRNA:decreased expression:leukocyte RGD PMID:20514434 RGD:4892076 Ensembl chr10:134,839,025...134,852,719 JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G EPHX1 epoxide hydrolase 1 susceptibility ISO DNA:SNP:exon:p.Y113H (rs1051740) (human) RGD PMID:17159790 RGD:4889408 NCBI chr 1:201,271,366...201,306,635
Ensembl chr 1:206,272,866...206,307,581
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : RGD PMID:9055949 RGD:5490588 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8473757 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G LOC100977568 tenascin ISO protein:increased expression:pleura RGD PMID:10950882 RGD:4889594 NCBI chr 9:86,125,672...86,222,804
Ensembl chr 9:114,486,778...114,584,299
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24142982 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216
JBrowse link
G NOS2 nitric oxide synthase 2 ISO mRNA,protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12051993 PMID:12160931 RGD:4891438 RGD:4891441 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr 1:44,813,508...44,824,430
Ensembl chr 1:46,171,453...46,182,018
JBrowse link
G PRDX2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr19:12,359,084...12,363,552
Ensembl chr19:13,103,422...13,107,369
JBrowse link
G SERPINA1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12368052 NCBI chr14:75,001,714...75,014,214
Ensembl chr14:94,334,258...94,345,419
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16221779 PMID:21514415 NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8473757 PMID:20486865 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TPM4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr19:15,557,683...15,593,143
Ensembl chr19:16,540,805...16,575,312
JBrowse link
Asphyxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha ISO mRNA, protein:increased expression:myocardium, lung (rat) RGD PMID:17285858 RGD:9068458 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G IFT80 intraflagellar transport 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17468754 NCBI chr 3:157,279,076...157,421,478
Ensembl chr 3:165,329,056...165,454,905
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:18620825 RGD:4890002 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G SOX4 SRY-box transcription factor 4 ISO RGD PMID:12011571 RGD:1581119 NCBI chr 6:21,422,846...21,427,779 JBrowse link
asphyxia neonatorum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO mRNA:increased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819
JBrowse link
G ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit ISO mRNA:decreased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr2B:32,983,492...33,020,492
Ensembl chr2B:127,922,483...127,959,372
JBrowse link
G GSTM1 glutathione S-transferase mu 1 severity ISO DNA:deletion, haplotype:: (human) RGD PMID:21058530 RGD:12792218 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G HTRA2 HtrA serine peptidase 2 treatment ISO protein:increased expression:kidney: RGD PMID:20704803 RGD:10402931 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152
JBrowse link
G MAP2 microtubule associated protein 2 ISO RGD PMID:21858873 RGD:6483085 NCBI chr2B:96,681,268...96,991,650
Ensembl chr2B:215,314,857...215,391,728
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO protein:increased expression:hippocampus: RGD PMID:15453273 RGD:9999183 NCBI chr15:22,706,520...22,731,672
Ensembl chr15:40,794,144...40,821,763
JBrowse link
G PSEN1 presenilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PSEN2 presenilin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G S100B S100 calcium binding protein B ISO protein:increased expression:urine RGD PMID:14707571 RGD:5508819 NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953
JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr21:18,029,831...18,037,526 JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17963755 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G XRCC1 X-ray repair cross complementing 1 ISO mRNA:increased expression:brain RGD PMID:9763211 RGD:2302855 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520
JBrowse link
berylliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:10194187 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853
JBrowse link
G BTNL2 butyrophilin like 2 susceptibility ISO DNA:SNP: :rs3117099(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17927685 RGD:9685029 NCBI chr 6:32,067,223...32,126,032 JBrowse link
G CCR5 C-C motif chemokine receptor 5 disease_progression ISO DNA:polymorphisms:5' utr:multiple (human) RGD PMID:20075058 RGD:4892065 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
G CD28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12952926 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766924 NCBI chr 1:96,548,850...96,573,273
Ensembl chr 1:95,278,665...95,297,893
JBrowse link
G HMOX1 heme oxygenase 1 ISO protein:increased activity:sputum RGD PMID:19453654 RGD:4145349 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8977230 NCBI chr10:6,053,549...6,103,863 JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:8105536 PMID:11551429 PMID:14662898 PMID:15273960 PMID:17927685 More... NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387
JBrowse link
G TGFB1 transforming growth factor beta 1 severity ISO DNA:polymorphisms: :-509C>T (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15750822 PMID:17785866 RGD:4145294 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 PMID:12449171 PMID:15127972 PMID:16980557 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
Birth Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:multiple organs (rat) RGD PMID:18554634 RGD:4890426 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
Blast Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein ISO RGD PMID:24224042 RGD:10054251 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072
JBrowse link
Bone Fractures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:19884440 RGD:2317529 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO associated with kidney failure, chronic; RGD PMID:21784896 RGD:7207231 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432
JBrowse link
G BMP2 bone morphogenetic protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP7 bone morphogenetic protein 7 ISO CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO RGD PMID:8432871 RGD:734801 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G ESR1 estrogen receptor 1 no_association ISO DNA:SNP, repeat:promoter:rs2234693 (human)
DNA:SNP:intron:rs9340799 (human)
RGD PMID:15523071 RGD:10045827 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G FAM210A family with sequence similarity 210 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr18:598,267...657,131
Ensembl chr18:2,767,335...2,827,533
JBrowse link
G FGF2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus, Experimental RGD PMID:8033826 RGD:2315907 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G GDF2 growth differentiation factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:27394662 NCBI chr10:46,520,808...46,526,414 JBrowse link
G IRX5 iroquois homeobox 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22581230 NCBI chr16:35,164,884...35,168,189
Ensembl chr16:54,272,412...54,275,124
JBrowse link
G LRP5 LDL receptor related protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817
JBrowse link
G MEPE matrix extracellular phosphoglycoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 4:80,125,612...80,139,539
Ensembl chr 4:90,838,938...90,864,332
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:21788831 RGD:6771211 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18795192 RGD:5135218 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G PTH parathyroid hormone ISO CTD Direct Evidence: therapeutic
associated with Renal Insufficiency, Chronic; protein:increased expression:serum (human)
CTD
RGD
PMID:16094769 PMID:23043229 RGD:7242731 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO RGD PMID:21252473 RGD:11252151 NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389
JBrowse link
G SLC25A13 solute carrier family 25 member 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr 7:88,072,139...88,273,470
Ensembl chr 7:101,658,507...101,859,587
JBrowse link
G SMAD6 SMAD family member 6 ISO RGD PMID:11920662 RGD:724455 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SOX9 SRY-box transcription factor 9 ISO RGD PMID:21252473 RGD:11252151 NCBI chr17:66,028,737...66,034,122 JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22504420 NCBI chr2A:54,608,711...54,816,083
Ensembl chr2A:55,822,415...55,961,925
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20358619 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15071724 NCBI chr 1:10,915,743...10,957,765
Ensembl chr 1:12,130,663...12,172,646
JBrowse link
brain compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFL1 cofilin 1 treatment ISO RGD PMID:25708984 RGD:12738361 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806
JBrowse link
Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:26448536 RGD:13506960 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:26448536 RGD:13506960 NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403
JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:26448536 RGD:13506960 NCBI chr11:640,401...646,775 JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:27113205 RGD:11062140 NCBI chr 7:23,415,922...23,420,767 JBrowse link
Brain Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 treatment ISO RGD PMID:21107131 RGD:12791995 NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870
JBrowse link
G ACAN aggrecan ISO mRNA:increased expression:fascia dentata (rat) RGD PMID:18511192 RGD:2315807 NCBI chr15:67,492,494...67,563,265
Ensembl chr15:86,733,853...86,771,420
JBrowse link
G ACTR2 actin related protein 2 ISO mRNA, protein:decreased expression:hippocampus (rat) RGD PMID:22120305 RGD:11530046 NCBI chr2A:65,289,675...65,333,219 JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:16689670 RGD:2325298 NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749
JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO mRNA:increased expression:frontal cortex RGD PMID:20974230 RGD:5688366 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:increased expression:brain (rat) RGD PMID:22491548 PMID:22915134 PMID:24859607 RGD:7245513 RGD:7245557 RGD:8696001 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G AIF1 allograft inflammatory factor 1 ISO protein:increased expression:cerebral cortex (rat) RGD PMID:19520144 RGD:2313020 NCBI chr 6:31,276,215...31,278,051
Ensembl chr 6:32,166,301...32,168,125
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nucleus: RGD PMID:12091479 RGD:10053567 NCBI chr  X:119,256,425...119,292,612
Ensembl chr  X:129,550,287...129,586,271
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO protein:increased phosphorylation:brain, neuron RGD PMID:16234845 RGD:5509090 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756
JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:7909931 PMID:17188501 NCBI chr 4:50,773,244...50,790,474
Ensembl chr 4:56,605,322...56,622,418
JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:urine RGD PMID:14592616 RGD:6904155 NCBI chr 9:85,157,680...85,176,253
Ensembl chr 9:113,525,835...113,543,422
JBrowse link
G ANK3 ankyrin 3 ISO RGD PMID:20557305 RGD:6767288 NCBI chr10:56,560,589...57,269,952
Ensembl chr10:58,790,696...59,602,954
JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A ISO RGD PMID:24385964 RGD:10401136 NCBI chr15:47,736,770...47,778,763 JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO protein:increased expression:cerebral cortex RGD PMID:11567033 RGD:2325751 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939
JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO mRNA:increased expression:brain RGD PMID:12707777 RGD:2301208 NCBI chr11:6,526,477...6,550,509
Ensembl chr11:6,209,812...6,225,972
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11447995 NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542
JBrowse link
G APOD apolipoprotein D ISO mRNA, protein:increased expression:cerebral cortex, glia cell, neuron RGD PMID:10501208 RGD:2311202 NCBI chr 3:192,852,887...192,868,233
Ensembl chr 3:203,152,476...203,168,060
JBrowse link
G APP amyloid beta precursor protein ISO protein:increased expression:hippocampus RGD PMID:16300758 RGD:10054281 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072
JBrowse link
G AQP4 aquaporin 4 ISO protein:increased expression:cerebral cortex RGD PMID:21083433 PMID:21488209 RGD:5148014 RGD:5148034 NCBI chr18:20,108,607...20,122,381
Ensembl chr18:23,713,146...23,726,919
JBrowse link
G ASIC1 acid sensing ion channel subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr12:38,672,253...38,698,247 JBrowse link
G ASTN1 astrotactin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr 1:152,385,103...152,688,885
Ensembl chr 1:156,085,398...156,284,771
JBrowse link
G ATG12 autophagy related 12 ISO protein:altered localization:brain RGD PMID:18059433 RGD:2301217 NCBI chr 5:111,184,617...111,196,038 JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d treatment ISO RGD PMID:26813465 RGD:13800884 NCBI chr17:68,986,362...68,994,246
Ensembl chr17:74,541,363...74,549,700
JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO mRNA:increased expression:cerebral cortex RGD PMID:17244947 RGD:2300372 NCBI chr12:25,793,633...25,803,026
Ensembl chr12:26,065,882...26,075,972
JBrowse link
G BAD BCL2 associated agonist of cell death ISO mRNA, protein:increased expression:cerebral cortex RGD PMID:15941375 RGD:2292694 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCAT1 branched chain amino acid transaminase 1 ISO Protein:increased expression:neurons RGD PMID:10686349 RGD:631308 NCBI chr12:61,364,154...61,500,827
Ensembl chr12:63,978,116...64,107,463
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:18093155 PMID:20888848 RGD:10054247 RGD:2293059 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BDNF brain derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:15500971 PMID:20544832 PMID:21269288 RGD:4891136 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239
JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:brain
protein:increased expression:hippocampus
protein:increased expression:neuron, astrocyte
RGD PMID:16874043 PMID:18500386 PMID:24221859 RGD:11558018 RGD:6483098 RGD:6483314 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO mRNA, protein:increased expression:brain, astrocyte, neuron RGD PMID:15453988 RGD:2293136 NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO protein:increased expression:brain, astrocyte, neuron RGD PMID:16388909 RGD:2289020 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO mRNA:increased expression:dentate gyrus, neuron RGD PMID:9080432 RGD:5129488 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G BYSL bystin like ISO mRNA, protein:increased expression:substantia nigra, striatum (rat) RGD PMID:15305856 RGD:2316201 NCBI chr 6:41,504,652...41,516,541
Ensembl chr 6:42,806,531...42,821,518
JBrowse link
G C3 complement C3 ISO RGD PMID:23808389 RGD:10054313 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO RGD PMID:25089700 RGD:11576302 NCBI chr  X:33,967,329...34,374,385
Ensembl chr  X:41,659,295...42,066,570
JBrowse link
G CASP1 caspase 1 ISO mRNA, protein:increased expression:brain RGD PMID:17188500 RGD:2315917 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP8 caspase 8 ISO protein:altered localization RGD PMID:15590916 RGD:1624191 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CAST calpastatin severity ISO mRNA:increased expression:cerebral cortex RGD PMID:15307896 RGD:5509821 NCBI chr 5:91,972,572...92,084,657
Ensembl chr 5:97,527,071...97,636,650
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:brain, neuron
RGD
CTD
PMID:11113322 PMID:19210118 PMID:21549006 RGD:2306999 RGD:9587789 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CCL20 C-C motif chemokine ligand 20 treatment ISO RGD PMID:22040257 RGD:7483630 NCBI chr2B:115,052,768...115,056,479
Ensembl chr2B:233,862,505...233,866,225
JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:hippocampus RGD PMID:24344922 RGD:8552265 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
G CD14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:135,996,265...135,997,909
Ensembl chr 5:142,113,082...142,118,966
JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:23924471 RGD:7248749 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G CD40LG CD40 ligand treatment ISO RGD PMID:11755016 PMID:25972624 RGD:11344972 RGD:8547803 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:increased expression:nucleus: RGD PMID:9914434 RGD:8662346 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO mRNA, protein:increased expression:cerebral cortex (mouse) RGD PMID:19833158 RGD:10401206 NCBI chr19:30,223,567...30,226,204 JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:cerebral cortex (mouse)
CTD
RGD
PMID:19833158 PMID:21549006 RGD:10401206 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CFB complement factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17474994 NCBI chr 6:31,606,716...31,612,782 JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:128,827,089...128,978,496
Ensembl chr 7:141,466,396...141,467,796
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:10,525,535...10,667,227
Ensembl chr15:29,565,885...29,705,194
JBrowse link
G CLEC4E C-type lectin domain family 4 member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr12:8,620,618...8,627,610 JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase ISO protein:increased expression:hippocampus RGD PMID:20215974 RGD:6483336 NCBI chr17:15,338,085...15,349,089
Ensembl chr17:15,560,056...15,568,916
JBrowse link
G COMT catechol-O-methyltransferase ISO protein:increased expression:hippocampus RGD PMID:17240060 RGD:2289740 NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387
JBrowse link
G CRP C-reactive protein disease_progression ISO RGD PMID:24456846 RGD:9585646 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CSF2 colony stimulating factor 2 disease_progression ISO RGD PMID:21515263 RGD:5686795 NCBI chr 5:127,496,951...127,499,325
Ensembl chr 5:133,660,775...133,663,146
JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21549006 PMID:24239694 RGD:11039431 NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 ISO protein:altered expression:cerebral cortex RGD PMID:19473238 RGD:5686860 NCBI chr15:54,583,010...54,621,240
Ensembl chr15:74,177,909...74,200,498
JBrowse link
G CUL5 cullin 5 ISO mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:17010517 RGD:2301432 NCBI chr11:102,895,611...102,994,447
Ensembl chr11:106,371,759...106,469,989
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO mRNA:increased expression:choroid plexus, cerebral cortex RGD PMID:19471279 RGD:5135009 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO protein:increased expression:brain, neuron RGD PMID:19210118 RGD:2306999 NCBI chr 4:50,092,989...50,095,541
Ensembl chr 4:55,925,562...55,986,555
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO mRNA:increased expression:hindbrain RGD PMID:16329132 RGD:1599699 NCBI chr15:53,280,110...53,310,868
Ensembl chr15:72,901,286...72,931,164
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:15774263 RGD:7243841 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:19429151 RGD:9588608 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 ISO protein:increased degradation:cerebral cortex, hippocampus RGD PMID:17402852 RGD:2303056 NCBI chr 8:25,786,950...25,927,782
Ensembl chr 8:22,693,863...22,834,080
JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18509630 RGD:2311580 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G DUSP5 dual specificity phosphatase 5 ISO mRNA:increased expression:cerebral cortex RGD PMID:12503083 RGD:2317873 NCBI chr10:107,091,147...107,105,971 JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:11526986 RGD:10395358 NCBI chr14:47,935,691...47,960,055
Ensembl chr14:66,813,953...66,839,866
JBrowse link
G EIF3E eukaryotic translation initiation factor 3 subunit E treatment ISO RGD PMID:22960363 RGD:10395371 NCBI chr 8:104,848,222...104,895,349 JBrowse link
G ELK1 ETS transcription factor ELK1 ISO RGD PMID:15362724 RGD:7488910 NCBI chr  X:40,071,433...40,086,518
Ensembl chr  X:47,967,492...47,982,579
JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO RGD PMID:22960363 RGD:10395371 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560
JBrowse link
G EPHA4 EPH receptor A4 ISO protein:increased expression, increased activity:astrocyte RGD PMID:22318127 RGD:5688763 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:21075124 RGD:5688356 NCBI chr 8:26,761,090...26,818,436
Ensembl chr 8:23,964,094...24,017,749
JBrowse link
G EPO erythropoietin treatment ISO CTD Direct Evidence: therapeutic
mRNA:increased expression:brain:
CTD
RGD
PMID:18093155 PMID:20833152 PMID:23063952 RGD:10401061 RGD:2293059 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974
JBrowse link
G EPOR erythropoietin receptor ISO mRNA:increased expression:brain: RGD PMID:18093155 RGD:2293059 NCBI chr19:10,925,148...10,931,955
Ensembl chr19:11,635,248...11,642,383
JBrowse link
G F2 coagulation factor II, thrombin severity ISO RGD PMID:21355766 RGD:5147766 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:hippocampus
associated with Hyperoxia
RGD PMID:16078565 PMID:19107989 RGD:1600354 RGD:8662854 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FGF2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:21269288 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G FMR1 FMRP translational regulator 1 ISO protein:altered localization:hippocampus (rat) RGD PMID:16510718 RGD:11667962 NCBI chr  X:136,937,889...136,976,828
Ensembl chr  X:147,365,748...147,405,321
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:9630518 NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766
JBrowse link
G FOXP1 forkhead box P1 treatment ISO RGD PMID:26842647 RGD:11561903 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO protein:decreased expression:hippocampus RGD PMID:18501200 RGD:2307353 NCBI chr  X:143,972,798...143,988,960
Ensembl chr  X:153,843,092...153,860,674
JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:3,129,481...3,357,495
Ensembl chr15:23,981,359...24,058,357
JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:2,371,468...2,932,250
Ensembl chr15:24,409,611...24,959,987
JBrowse link
G GDNF glial cell derived neurotrophic factor ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 5:72,539,374...72,566,918
Ensembl chr 5:77,577,313...77,601,362
JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO RGD PMID:23485053 RGD:8662424 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GJA5 gap junction protein alpha 5 ISO protein:increased expression:cerebral artery RGD PMID:21895483 RGD:7207391 NCBI chr 1:123,200,111...123,224,626
Ensembl chr 1:112,328,337...112,329,413
JBrowse link
G GPX1 glutathione peroxidase 1 ISO mRNA:decreased expression:hippocampus, neuron RGD PMID:15791111 RGD:2306624 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826
JBrowse link
G GRM8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:118,430,086...119,249,147 JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22643085 PMID:24675465 RGD:10045646 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G GSN gelsolin ISO RGD PMID:14588109 RGD:1599864 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO mRNA,protein:decreased expression:hippocampus: RGD PMID:11726545 RGD:9686434 NCBI chr 5:64,673,392...65,116,259
Ensembl chr 5:69,724,767...70,158,761
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:22915134 RGD:7245513 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18562561 RGD:5508455 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:23470432 RGD:10755702 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A ISO mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:21549006 RGD:5147593 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:cerebral white matter (rat) RGD PMID:22067617 RGD:5688785 NCBI chr 5:128,463,186...128,517,563
Ensembl chr 5:134,619,076...134,673,658
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO RGD PMID:11746764 RGD:6480530 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984
JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:22465320 RGD:6482178 NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:brain: RGD PMID:16230799 RGD:11522716 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G IGF1 insulin like growth factor 1 treatment ISO human protein in a rat model RGD PMID:9344566 RGD:12904928 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IGF2 insulin like growth factor 2 ISO mRNA:decreased expression:brain RGD PMID:11123717 RGD:5509972 NCBI chr11:2,170,190...2,199,442
Ensembl chr11:2,202,743...2,228,890
JBrowse link
G IL10 interleukin 10 severity
treatment
ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:21549006 PMID:23075771 PMID:23971414 RGD:7364822 RGD:7364983 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:66,549,650...66,640,623
Ensembl chr 1:68,543,509...68,612,168
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:104,092,993...104,146,062
Ensembl chr  X:114,597,077...114,635,253
JBrowse link
G IL16 interleukin 16 ISO RGD PMID:17983426 RGD:5024939 NCBI chr15:60,181,827...60,299,406
Ensembl chr15:79,122,988...79,250,861
JBrowse link
G IL17RD interleukin 17 receptor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:57,023,622...57,098,869
Ensembl chr 3:58,240,835...58,309,409
JBrowse link
G IL18 interleukin 18 severity ISO mRNA, protein:increased expression:brain RGD PMID:17188500 RGD:2315917 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr2A:99,419,686...99,462,650 JBrowse link
G IL1A interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:cerebral cortex
CTD
RGD
PMID:16024175 PMID:21549006 RGD:2311098 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:brain, cerebrospinal fluid
mRNA, protein:increased expression:cerebral cortex
mRNA, protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16024175 PMID:17612572 PMID:19800810 PMID:21549006 PMID:22503903 RGD:1626652 RGD:2311098 RGD:6482651 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 Ensembl chr2A:103,193,131...103,230,005 JBrowse link
G IL2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL3 interleukin 3 disease_progression ISO protein: increased expression: brain: microdialysis perfusate RGD PMID:20717122 PMID:21515263 RGD:5686795 RGD:5686886 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213
JBrowse link
G IL31RA interleukin 31 receptor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:58,101,135...58,167,317
Ensembl chr 5:59,722,621...59,793,518
JBrowse link
G IL4 interleukin 4 ISO protein:decreased expression:plasma RGD PMID:24519543 RGD:10402802 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:24530657 PMID:24602693 RGD:11522766 RGD:11522770 NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675
JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:cerebrospinal fluid (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10027774 PMID:19800810 PMID:21549006 PMID:23159883 RGD:11049549 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL7 interleukin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 8:75,254,166...75,337,373
Ensembl chr 8:76,895,095...76,966,918
JBrowse link
G IRF1 interferon regulatory factor 1 ISO mRNA:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12503083 PMID:21549006 RGD:2317873 NCBI chr 5:127,903,887...127,913,843
Ensembl chr 5:134,067,441...134,075,035
JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21596098 RGD:6483023 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:20861444 RGD:8662901 NCBI chr 1:135,391,321...135,424,100 JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:cerebral cortex RGD PMID:19733172 PMID:21307798 RGD:5684382 RGD:5684402 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G LEP leptin ISO RGD PMID:21276361 RGD:5128517 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G LOC100978213 TNF superfamily member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:7,581,163...7,589,809
Ensembl chr17:7,567,766...7,575,575
JBrowse link
G LOC100986475 metallothionein-2 ISO mRNA:increased expression:liver (mouse)
mRNA:increased expression:dentate gyrus (rat)
RGD PMID:15650329 PMID:22363575 RGD:6483812 RGD:6483847 NCBI chr16:36,894,853...36,895,826
Ensembl chr16:56,007,922...56,028,093
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein ISO CTD Direct Evidence: therapeutic CTD PMID:25665855 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G LOC100991889 interleukin-9 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 9:109,268,011...109,277,418
Ensembl chr  X:155,373,324...155,386,631
JBrowse link
G LOC100995326 serotransferrin ISO RGD PMID:22538758 RGD:7244386 NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476
JBrowse link
G LSG1 large 60S subunit nuclear export GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr 3:191,937,249...191,967,849
Ensembl chr 3:202,247,591...202,278,647
JBrowse link
G LY86 lymphocyte antigen 86 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 6:6,429,846...6,496,664
Ensembl chr 6:6,610,431...6,676,696
JBrowse link
G MAG myelin associated glycoprotein susceptibility ISO RGD PMID:17156367 RGD:9685230 NCBI chr19:32,238,457...32,260,497
Ensembl chr19:40,975,763...40,997,401
JBrowse link
G MAP1B microtubule associated protein 1B ISO protein:increased expression, increased phosphorylation:brain RGD PMID:10906717 RGD:2304029 NCBI chr 5:43,102,739...43,204,978
Ensembl chr 5:43,701,530...43,803,393
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:24221859 RGD:11558018 NCBI chr20:30,887,345...30,888,986
Ensembl chr20:32,010,284...32,020,411
JBrowse link
G MAP2 microtubule associated protein 2 ISO protein:decreased expression:cerebral cortex, neuron RGD PMID:20568963 PMID:21401443 RGD:6483087 RGD:6483089 NCBI chr2B:96,681,268...96,991,650
Ensembl chr2B:215,314,857...215,391,728
JBrowse link
G MBL2 mannose binding lectin 2 disease_progression ISO RGD PMID:18183030 RGD:12910935 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G MBP myelin basic protein ISO RGD PMID:18583256 RGD:7349333 NCBI chr18:70,369,882...70,526,693
Ensembl chr18:73,629,522...73,755,351
JBrowse link
G MDM2 MDM2 proto-oncogene ISO protein:increased expression:brain cortex (rat) RGD PMID:15165363 RGD:2317397 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278
JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:15922484 RGD:1641989 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16671440 PMID:19631748 PMID:24661104 RGD:13207312 RGD:1582656 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G MT3 metallothionein 3 treatment ISO RGD PMID:10218634 PMID:10595827 PMID:16314047 RGD:6480628 RGD:9685803 RGD:9685805 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093
JBrowse link
G MYOC myocilin ISO mRNA:increased expression:cerebral cortex (rat) RGD PMID:12799138 RGD:7401267 NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:lung: RGD PMID:18787991 PMID:25089700 RGD:11576302 RGD:5134971 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G NGB neuroglobin severity ISO RGD PMID:21915648 RGD:9743963 NCBI chr14:57,818,491...57,824,196
Ensembl chr14:77,020,274...77,025,983
JBrowse link
G NGFR nerve growth factor receptor treatment ISO RGD PMID:23940017 RGD:10414074 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966
JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:11526986 RGD:10395358 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G NPPB natriuretic peptide B ISO CTD Direct Evidence: therapeutic
associated with lung diseases;protein:increased expression:serum:
CTD
RGD
PMID:19803787 PMID:23837838 RGD:7247620 NCBI chr 1:10,621,416...10,622,960
Ensembl chr 1:11,838,518...11,839,995
JBrowse link
G NPY neuropeptide Y ISO protein:increased expression:adrenal medulla RGD PMID:23570732 RGD:10448961 NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO mRNA:increased expression:lung
associated with Subarachnoid Hemorrhage
RGD PMID:18787991 PMID:20864352 RGD:11035222 RGD:5134971 NCBI chr16:50,090,696...50,106,495
Ensembl chr16:69,470,288...69,489,731
JBrowse link
G NT5E 5'-nucleotidase ecto ISO protein:altered expression:cerebral cortex (rat) RGD PMID:21337375 RGD:5134348 NCBI chr 6:83,333,428...83,379,585
Ensembl chr 6:86,615,409...86,661,601
JBrowse link
G P2RY1 purinergic receptor P2Y1 ISO protein:increased expression:brain, astrocyte RGD PMID:19115395 RGD:2315811 NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813
JBrowse link
G PALLD palladin, cytoskeletal associated protein ISO protein:increased expression:brain, astrocyte RGD PMID:12932445 RGD:2325786 NCBI chr 4:160,718,475...161,140,436 JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA,protein:increased expression:brain: RGD PMID:11421591 RGD:9835358 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796
JBrowse link
G PDE4D phosphodiesterase 4D ISO mRNA, protein:alternative form, decreased phosphorylation:brain RGD PMID:23057870 RGD:7327147 NCBI chr 5:53,510,287...55,039,181
Ensembl chr 5:55,749,214...56,670,111
JBrowse link
G PDGFA platelet derived growth factor subunit A ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22658532 RGD:6484732 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr19:43,033,080...43,037,726
Ensembl chr19:51,569,275...51,573,764
JBrowse link
G PGR progesterone receptor ISO RGD PMID:23211561 RGD:7248711 NCBI chr11:95,997,677...96,098,866 JBrowse link
G PHB prohibitin ISO protein:increased oxidation:cerebral cortex RGD PMID:17518533 RGD:2292409 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790
JBrowse link
G PHB2 prohibitin 2 ISO RGD PMID:24566151 RGD:12903261 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 ISO protein:decreased expression:brain, nucleus RGD PMID:21545521 RGD:8693413 NCBI chr15:47,006,718...47,141,035
Ensembl chr15:65,276,530...65,410,105
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO agonist more effective in combination with simvastatin RGD PMID:18562561 RGD:5508455 Ensembl chr22:45,218,364...45,302,970 JBrowse link
G PPARGC1A PPARG coactivator 1 alpha treatment ISO protein:decreased expression:frontal cortex (rat) RGD PMID:22642418 PMID:24345766 RGD:10059630 RGD:6484257 NCBI chr 4:18,196,431...18,876,889
Ensembl chr 4:23,483,377...23,581,212
JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO protein: :hippocampus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:14499481 PMID:19751097 RGD:6483311 NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394
JBrowse link
G PRF1 perforin 1 ISO RGD PMID:20537642 RGD:6482807 NCBI chr10:67,071,141...67,078,057
Ensembl chr10:69,597,574...69,603,070
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO protein:increased expression:striatum, microglia (rat) RGD PMID:15234107 RGD:9850280 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia, macrophage
protein:increased expression:microglial cells, macrophage, endothelial cell
RGD PMID:11565600 PMID:12005397 PMID:19719848 RGD:5688162 RGD:5688239 RGD:5688242 NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12410334 PMID:19719848 PMID:20810888 PMID:21549006 PMID:21866634 RGD:5508191 RGD:5688162 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:12088737 RGD:727637 NCBI chr 7:113,882,557...114,073,283
Ensembl chr 7:126,569,630...126,758,155
JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 ISO protein:increased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr 4:48,691,213...48,725,979
Ensembl chr 4:54,526,202...54,561,048
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:ileum RGD PMID:18288455 RGD:2298787 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr10:40,050,396...40,103,629
Ensembl chr10:43,249,468...43,284,331
JBrowse link
G RHOA ras homolog family member A ISO protein:increased expression:microglial cell, brain RGD PMID:17929039 RGD:2298888 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308
JBrowse link
G ROBO2 roundabout guidance receptor 2 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 3:76,013,780...77,764,156
Ensembl chr 3:79,030,223...79,632,309
JBrowse link
G ROBO3 roundabout guidance receptor 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr11:119,692,232...119,708,309
Ensembl chr11:123,607,268...123,623,356
JBrowse link
G RPS27A ribosomal protein S27a ISO mRNA:decreased expression:cerebral cortex, hippocampus RGD PMID:17936732 RGD:11041870 NCBI chr2A:55,389,243...55,392,914
Ensembl chr2A:56,530,349...56,533,527
JBrowse link
G S100B S100 calcium binding protein B severity ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:11520488 PMID:21783483 PMID:21976236 RGD:5508761 NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953
JBrowse link
G SELE selectin E ISO protein:increased expression:brain RGD PMID:19107536 RGD:2313599 NCBI chr 1:145,205,684...145,217,143
Ensembl chr 1:148,930,437...148,938,313
JBrowse link
G SERPINC1 serpin family C member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21534203 NCBI chr 1:149,421,737...149,435,301
Ensembl chr 1:153,126,031...153,139,369
JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO protein:altered expression:cerebellum (rat)
human gene in a rat model
RGD PMID:17709187 PMID:20142768 RGD:8612994 RGD:8622925 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568
JBrowse link
G SIRT1 sirtuin 1 treatment ISO RGD PMID:17970622 RGD:9497541 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069
JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO protein:increased expression:brain RGD PMID:19852587 RGD:2315049 NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311
JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO protein:decreased expression:brain RGD PMID:18848922 RGD:5686682 NCBI chr10:44,630,006...44,632,419 JBrowse link
G SLIT1 slit guidance ligand 1 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr10:93,618,550...93,806,263
Ensembl chr10:97,119,133...97,303,095
JBrowse link
G SLIT3 slit guidance ligand 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 5:164,029,432...164,664,156
Ensembl chr 5:170,793,731...171,425,242
JBrowse link
G SNCA synuclein alpha ISO RGD PMID:14637093 PMID:25089700 RGD:11576302 RGD:6480195 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600
JBrowse link
G SNCB synuclein beta ISO RGD PMID:14637093 RGD:6480195 NCBI chr 5:171,918,297...171,928,672
Ensembl chr 5:178,988,439...178,998,800
JBrowse link
G SNCG synuclein gamma ISO RGD PMID:14637093 RGD:6480195 NCBI chr10:83,383,566...83,391,064 JBrowse link
G SNW1 SNW domain containing 1 ISO mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22965216 RGD:11035237 NCBI chr14:58,271,830...58,315,773
Ensembl chr14:77,472,387...77,517,315
JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:16248885 RGD:1581214 NCBI chr21:18,029,831...18,037,526 JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:16248885 PMID:24462953 RGD:1581214 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA:increased expression:brain, blood vessel RGD PMID:9704602 RGD:2300066 NCBI chr 5:147,087,903...147,112,466
Ensembl chr 5:153,090,181...153,115,750
JBrowse link
G SSTR2 somatostatin receptor 2 ISO RGD PMID:11879809 RGD:2325002 NCBI chr17:67,093,013...67,099,086
Ensembl chr17:72,553,506...72,554,615
JBrowse link
G SSTR3 somatostatin receptor 3 ISO RGD PMID:11879809 RGD:2325002 NCBI chr22:18,116,993...18,125,170
Ensembl chr22:35,954,232...35,955,488
JBrowse link
G SSTR4 somatostatin receptor 4 ISO RGD PMID:11879809 RGD:2325002 NCBI chr20:22,982,009...22,986,058
Ensembl chr20:23,333,320...23,334,766
JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:21596098 RGD:6483023 NCBI chr2B:78,270,642...78,316,074
Ensembl chr2B:196,186,906...196,232,280
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:brain RGD PMID:21596098 PMID:22145815 PMID:22827467 RGD:6483023 RGD:6892706 RGD:8694312 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G STRN striatin ISO RGD PMID:16351572 RGD:2311293 NCBI chr2A:36,870,487...36,993,103
Ensembl chr2A:37,637,543...37,713,550
JBrowse link
G TARDBP TAR DNA binding protein ISO RGD PMID:22101322 RGD:5687195 NCBI chr 1:9,775,084...9,786,710
Ensembl chr 1:10,996,006...11,008,732
JBrowse link
G TH tyrosine hydroxylase ISO protein:decreased activity:striatum (rat) RGD PMID:21047500 RGD:5128822 NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433
JBrowse link
G THBD thrombomodulin onset ISO RGD PMID:17895610 RGD:5685007 NCBI chr20:22,992,341...22,996,415
Ensembl chr20:23,345,917...23,347,812
JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:110,935,649...110,960,019
Ensembl chr 5:116,734,092...116,734,799
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO mRNA:increased expression:brain, astrocytes RGD PMID:10719361 RGD:2290468 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO mRNA:increased expression:brain, neuron, microglial cell RGD PMID:10719361 RGD:2290468 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649
JBrowse link
G TJP1 tight junction protein 1 ISO RGD PMID:19889224 RGD:2325128 NCBI chr15:981,198...1,249,292
Ensembl chr15:26,344,878...26,598,878
JBrowse link
G TLR1 toll like receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:33,119,485...33,133,541
Ensembl chr 4:38,979,006...38,981,366
JBrowse link
G TLR2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:brain
CTD
RGD
PMID:18316784 PMID:21549006 RGD:2312713 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
G TLR4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:brain
CTD
RGD
PMID:18316784 PMID:21549006 RGD:2312713 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:10674461 PMID:19800810 PMID:21549006 RGD:13825262 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF13B TNF receptor superfamily member 13B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:34,321,121...34,355,020
Ensembl chr17:39,252,858...39,292,053
JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr22:22,816,504...22,819,584 JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:1,288,493...1,296,532
Ensembl chr 1:2,427,631...2,435,615
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17074049 PMID:21549006 RGD:1624183 NCBI chr12:6,457,617...6,470,969
Ensembl chr12:6,374,257...6,387,613
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:169,512,491...169,530,706
Ensembl chr 3:177,694,021...177,712,137
JBrowse link
G TRAF4 TNF receptor associated factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:28,025,288...28,031,379
Ensembl chr17:28,531,867...28,536,994
JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 ISO mRNA, protein:increased expression:cerebral cortex, hippocampus RGD PMID:20309649 RGD:9999437 NCBI chr21:30,606,825...30,737,313
Ensembl chr21:43,903,811...44,035,298
JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:17936732 RGD:11041870 NCBI chr19:18,040,946...18,052,445 JBrowse link
G UCP2 uncoupling protein 2 ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:12858170 RGD:7204436 NCBI chr11:69,047,397...69,056,056
Ensembl chr11:72,354,529...72,363,185
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:12230324 PMID:18065154 RGD:1580574 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
G VEGFB vascular endothelial growth factor B ISO mRNA, protein:increased expression:brain RGD PMID:12230324 RGD:1580574 NCBI chr11:59,591,750...59,595,926 JBrowse link
G VIM vimentin ISO protein:increased expression:brain RGD PMID:15527750 PMID:19728994 RGD:6480519 RGD:6480527 NCBI chr10:17,546,389...17,554,702
Ensembl chr10:17,818,285...17,826,642
JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:26528358 RGD:13208950 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link
Brain Injuries, Diffuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S100B S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:30076900 NCBI chr21:33,063,845...33,070,073
Ensembl chr21:46,197,750...46,203,953
JBrowse link
Brain Injuries, Traumatic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 ISO RGD PMID:22489706 RGD:13703033 NCBI chr15:37,562,930...37,717,175
Ensembl chr15:55,873,606...56,027,188
JBrowse link
G APP amyloid beta precursor protein treatment ISO RGD PMID:29320530 RGD:13782048 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072
JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO RGD PMID:24582457 RGD:13782254 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G CAPN1 calpain 1 ISO protein:increased expression:cytosol, plasma membrane RGD PMID:9469158 RGD:13792664 NCBI chr11:60,545,837...60,576,631
Ensembl chr11:63,886,015...63,916,021
JBrowse link
G CAPN2 calpain 2 ISO RGD PMID:9469158 RGD:13792664 NCBI chr 1:199,335,582...199,399,267
Ensembl chr 1:204,335,573...204,409,150
JBrowse link
G CD163 CD163 molecule ISO protein:increased expression:brain, macrophage (rat) RGD PMID:22583855 RGD:127285798 NCBI chr12:7,616,714...7,649,768
Ensembl chr12:7,775,343...7,810,023
JBrowse link
G CD8A CD8a molecule ISO mRNA:increased expression:brain (mouse) RGD PMID:31383034 RGD:124715446 NCBI chr2A:86,832,559...86,855,772
Ensembl chr2A:88,377,722...88,382,635
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment ISO RGD PMID:26435412 RGD:27095897 NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606
JBrowse link
G DRD1 dopamine receptor D1 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257
JBrowse link
G DRD2 dopamine receptor D2 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935
JBrowse link
G FUBP1 far upstream element binding protein 1 ISO RGD PMID:23797733 RGD:13673879 NCBI chr 1:77,162,675...77,198,486 JBrowse link
G GNAL G protein subunit alpha L ISO RGD PMID:29215295 RGD:13513923 NCBI chr18:2,420,578...2,615,947 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G ITGB1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031
JBrowse link
G LAMA1 laminin subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr18:7,159,568...7,335,363
Ensembl chr18:9,482,895...9,656,800
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO protein:increased expression:hippocampus: RGD PMID:28365875 RGD:13703062 NCBI chr  X:109,700,185...109,743,579
Ensembl chr  X:119,886,982...119,929,896
JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:31539545 RGD:126781751 NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798
JBrowse link
G MAPT microtubule associated protein tau treatment ISO RGD PMID:25771151 PMID:26484783 PMID:26729399 PMID:28412141 RGD:13800902 RGD:13800909 RGD:13800912 RGD:13800917 NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G NCSTN nicastrin ISO RGD PMID:18240300 RGD:13801189 NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:brain: RGD PMID:30855558 RGD:26884463 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 1:8,712,798...8,753,027
Ensembl chr 1:9,942,491...9,982,364
JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G OCLN occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829224 PMID:28642177 NCBI chr 1:201,820,355...201,867,673
Ensembl chr 1:206,812,981...206,860,356
JBrowse link
G PDE10A phosphodiesterase 10A ISO RGD PMID:29215295 RGD:13513923 NCBI chr 6:163,274,252...163,612,749
Ensembl chr 6:168,265,707...168,645,231
JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:20713027 RGD:13830881 NCBI chr2A:68,227,282...68,300,482 JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:20713027 RGD:13830881 NCBI chr 9:72,796,099...72,799,499 JBrowse link
G PSEN1 presenilin 1 ISO RGD PMID:18240300 RGD:13801189 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 PMID:28642177 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:28433746 RGD:14995478 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TP53 tumor protein p53 treatment ISO RGD PMID:27553877 RGD:14995939 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G UBE4B ubiquitination factor E4B ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 1:8,801,707...8,949,465
Ensembl chr 1:10,033,084...10,178,759
JBrowse link
Bronchopulmonary Dysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator ISO RGD PMID:26431790 RGD:11537057 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BID BH3 interacting domain death agonist ISO RGD PMID:26431790 RGD:11537057 NCBI chr22:1,164,787...1,205,051
Ensembl chr22:16,594,186...16,632,844
JBrowse link
G CASP3 caspase 3 ISO RGD PMID:26431790 RGD:11537057 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP8 caspase 8 ISO RGD PMID:26431790 RGD:11537057 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G CASP9 caspase 9 ISO RGD PMID:26431790 RGD:11537057 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G CAT catalase ISO RGD PMID:19693467 RGD:5130750 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G CHI3L1 chitinase 3 like 1 ISO protein:decreased secretion:lung, secretion (human) RGD PMID:20558631 RGD:4892651 NCBI chr 1:178,778,081...178,789,704
Ensembl chr 1:183,075,312...183,083,229
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO RGD PMID:19951473 RGD:5134972 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
JBrowse link
G DAG1 dystroglycan 1 ISO DNA:SNP: :p.N494H (human) RGD PMID:17196572 RGD:11537474 NCBI chr 3:49,396,180...49,464,689
Ensembl chr 3:50,640,615...50,703,852
JBrowse link
G EDN1 endothelin 1 ISO protein:increased expression:lung (rat) RGD PMID:20647310 RGD:4144841 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545
JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO RGD PMID:23065129 RGD:10395385 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:22003089 RGD:10402122 NCBI chr13:9,584,850...9,779,542 JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion, haplotype:: (human) RGD PMID:24120392 RGD:12792215 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (human) RGD PMID:14726935 RGD:4142520 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:23065129 PMID:26431790 RGD:10395385 RGD:11537057 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15539764 PMID:16813970 RGD:4143172 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein susceptibility ISO protein:increased expression:lung
associated with Premature Birth;DNA:polymorphism::
RGD PMID:15539764 PMID:22882323 RGD:12910846 RGD:4143172 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO associated with Premature Birth;DNA:polymorphism:exon: RGD PMID:22882323 RGD:12910846 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G MIF macrophage migration inhibitory factor ISO associated with Respiratory Distress Syndrome, Newborn; protein:increased expression:lung RGD PMID:18097062 RGD:4891007 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:19097983 RGD:5129685 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MUC1 mucin 1, cell surface associated severity ISO protein:increased expression:cord plasma RGD PMID:18025794 RGD:5131170 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
G NFKBIA NFKB inhibitor alpha exacerbates ISO DNA:SNPs:promoter: (rs2233406, rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr14:16,155,331...16,158,588 JBrowse link
G POSTN periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363622 NCBI chr13:18,779,297...18,815,207
Ensembl chr13:37,368,030...37,407,212
JBrowse link
G SCGB1A1 secretoglobin family 1A member 1 ISO RGD PMID:11435254 RGD:5144211 NCBI chr11:57,774,560...57,780,334
Ensembl chr11:61,133,649...61,137,873
JBrowse link
G SERPINE1 serpin family E member 1 ISO associated with Premature Birth;protein:increased expression:blood: RGD PMID:25140773 RGD:13208551 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450
JBrowse link
G SFTPA1 surfactant protein A1 susceptibility ISO DNA:polymorphisms, haplotype: (human)
DNA:snps, haplotypes:multiple (human)
RGD PMID:11105614 PMID:17264398 RGD:4143384 RGD:4144876 NCBI chr10:76,571,312...76,575,820 JBrowse link
G SFTPB surfactant protein B susceptibility ISO DNA:deletion:intron (human)
DNA:polymorphism:intron (human)
RGD PMID:12424586 PMID:15102713 PMID:17264398 RGD:4143384 RGD:4143405 RGD:4143418 NCBI chr2A:85,708,485...85,718,120
Ensembl chr2A:87,257,244...87,268,332
JBrowse link
G SFTPD surfactant protein D ISO RGD PMID:17264398 RGD:4143384 NCBI chr10:76,275,147...76,318,952
Ensembl chr10:78,965,252...78,974,181
JBrowse link
G TNF tumor necrosis factor severity
no_association
ISO DNA:SNP:promoter:-238A>G (human)
DNA:SNP:promoter:-308G>A (human)
RGD PMID:15286263 RGD:12904049 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TP53 tumor protein p53 ISO RGD PMID:26431790 RGD:11537057 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G TXN thioredoxin ISO CTD Direct Evidence: therapeutic CTD PMID:20812253 NCBI chr 9:81,399,056...81,411,607
Ensembl chr 9:109,565,557...109,578,311
JBrowse link
G VDR vitamin D receptor susceptibility ISO associated with Premature Birth;DNA:SNPs: :rs2228570,rs731236(human) RGD PMID:24796371 RGD:13432055 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin disease_progression ISO RGD PMID:23917657 RGD:11036092 NCBI chr 4:50,773,244...50,790,474
Ensembl chr 4:56,605,322...56,622,418
JBrowse link
G BAD BCL2 associated agonist of cell death ISO protein:increased expression:neutrophil RGD PMID:15625305 RGD:2292697 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:22153006 RGD:10054126 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:22153006 RGD:10054126 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:24730400 RGD:11561936 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:22153006 RGD:10054126 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CCNC cyclin C ISO protein:increased expression:skin RGD PMID:16271231 RGD:2315993 NCBI chr 6:97,383,290...97,410,068
Ensembl chr 6:101,265,499...101,292,233
JBrowse link
G CCND1 cyclin D1 ISO RGD PMID:17996899 RGD:2289134 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CD14 CD14 molecule ISO mRNA:increased expression:multiple organs: RGD PMID:11829837 PMID:12435950 RGD:2313390 RGD:7204443 NCBI chr 5:135,996,265...135,997,909
Ensembl chr 5:142,113,082...142,118,966
JBrowse link
G CD86 CD86 molecule ISO protein:increased expression:spleen, dendritic cell (rat) RGD PMID:20233162 RGD:4892209 NCBI chr 3:119,151,884...119,217,641
Ensembl chr 3:126,059,008...126,124,339
JBrowse link
G CLDN1 claudin 1 ISO associated with Binge Drinking;protein: decreased tyrosine phosphorylation:intestine mucosa" RGD PMID:22001439 RGD:8655996 NCBI chr 3:187,328,629...187,345,360
Ensembl chr 3:195,882,239...195,899,248
JBrowse link
G CPB2 carboxypeptidase B2 ISO protein:increased activity:plasma RGD PMID:15497025 RGD:2313648 NCBI chr13:26,926,788...26,979,767 JBrowse link
G CRP C-reactive protein ISO RGD PMID:20664819 RGD:5131457 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO protein:increased expression:serum RGD PMID:18391855 RGD:5135231 NCBI chr 4:50,092,989...50,095,541
Ensembl chr 4:55,925,562...55,986,555
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO protein:decreased expression:heart,mitochondrion: RGD PMID:23041468 RGD:10401126 NCBI chr 6:71,342,291...71,346,033
Ensembl chr 6:74,629,688...74,633,754
JBrowse link
G FGA fibrinogen alpha chain ISO protein:increased expression:plasma (rat) RGD PMID:20664819 RGD:5131457 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO protein:increased expression:epidermis: RGD PMID:9204964 RGD:10402083 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISO protein:decreased phosphorylation, decreased activity:T cell (rat) RGD PMID:12353920 RGD:2324864 NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO mRNA:increased expression:heart left ventricle (rat) RGD PMID:29232706 RGD:13506829 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO protein:increased activity,altered phosphorylation:skeletal muscle: RGD PMID:17686886 RGD:10045647 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G GSTA4 glutathione S-transferase alpha 4 ISO mRNA:altered expression:fat, muscle, skin (human) RGD PMID:22038048 RGD:5687774 NCBI chr 6:52,532,942...52,550,404
Ensembl chr 6:54,171,318...54,188,976
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:Peyer's patches (rat) RGD PMID:19439119 RGD:9068477 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:20723408 RGD:10402183 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G IGF1 insulin like growth factor 1 ISO mRNA:altered expression:multiple RGD PMID:10827012 RGD:12910869 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:decreased expression:skeletal muscle: RGD PMID:25186839 RGD:10046020 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO mRNA:decreased expression:liver RGD PMID:10827012 RGD:12910869 NCBI chr16:412,671...418,351
Ensembl chr16:1,843,979...1,848,442
JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO mRNA:increased expression:kidney, liver RGD PMID:10827012 RGD:12910869 NCBI chr 7:46,538,566...46,545,536
Ensembl chr 7:46,658,097...46,662,584
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO mRNA:altered expression:kidney, liver, muscle RGD PMID:10827012 RGD:12910869 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO mRNA:increased expression:liver RGD PMID:11742840 RGD:1626551 NCBI chr 4:66,808,845...66,888,301
Ensembl chr 4:73,382,745...73,462,087
JBrowse link
G IL10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18277951 PMID:22341647 RGD:11049470 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL18 interleukin 18 ISO protein:decreased expression:liver RGD PMID:19197224 RGD:4889576 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL1A interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:10431976 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18277951 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10431976 PMID:18277951 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G LBP lipopolysaccharide binding protein ISO RGD PMID:12435950 RGD:2313390 NCBI chr20:34,670,128...34,703,046
Ensembl chr20:35,780,768...35,813,188
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:24730400 RGD:11561936 NCBI chr20:30,887,345...30,888,986
Ensembl chr20:32,010,284...32,020,411
JBrowse link
G MIF macrophage migration inhibitory factor ISO mRNA, protein:increased expression:liver, serum RGD PMID:14625478 RGD:1642001 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO mRNA:increased expression:ileum RGD PMID:15182445 RGD:9685358 NCBI chr11:97,467,037...97,477,305
Ensembl chr11:100,960,032...100,971,099
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO mRNA, protein:increased expression:brain RGD PMID:17156757 RGD:1642051 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:kidney, lung
CTD
RGD
PMID:11996850 PMID:22356815 RGD:6909170 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G MSTN myostatin ISO mRNA:increased expression:skeletal muscle RGD PMID:11481237 RGD:2303598 NCBI chr2B:77,364,927...77,452,426
Ensembl chr2B:195,283,903...195,290,922
JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO protein:increased serine phosphorylation:skeletal muscle RGD PMID:20594757 RGD:10041043 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO protein:increased expression:neutrophil RGD PMID:9329126 RGD:2314453 NCBI chr 1:159,085,923...159,121,259
Ensembl chr 1:163,243,636...163,278,420
JBrowse link
G NGF nerve growth factor ISO RGD PMID:12133564 RGD:5144074 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15650120 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment ISO protein:decreased activity:liver, lung, kidney RGD PMID:11990926 PMID:19216853 RGD:4892319 RGD:7174720 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G OCLN occludin ISO associated with Binge Drinking;protein:decreased expression, decreased tyrosine, threonine phosphorylation:intestine mucosa: RGD PMID:22001439 RGD:8655996 NCBI chr 5:44,447,230...44,509,637
Ensembl chr 5:46,023,437...46,069,342
JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 ISO protein:increased expression:ileum (rat) RGD PMID:15449568 RGD:2326198 NCBI chr 5:68,528,765...68,668,305
Ensembl chr 5:73,563,758...73,710,316
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:17826914 RGD:2304127 NCBI chr20:3,157,246...3,159,013 JBrowse link
G PDCD1 programmed cell death 1 treatment ISO associated with Pseudomonas Infections RGD PMID:29345058 RGD:41410788 NCBI chr2B:129,111,509...129,121,127 JBrowse link
G PDE4B phosphodiesterase 4B ISO mRNA:increased expression:extensor digitorum longus muscle RGD PMID:29693432 RGD:13782127 NCBI chr 1:65,038,120...65,620,764
Ensembl chr 1:67,045,911...67,506,291
JBrowse link
G PKLR pyruvate kinase L/R ISO RGD PMID:12417155 RGD:1625591 NCBI chr 1:130,634,111...130,646,644
Ensembl chr 1:134,239,565...134,251,351
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO protein:increased expression:heart RGD PMID:17483741 RGD:1642444 NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101
JBrowse link
G PLAT plasminogen activator, tissue type ISO protein:increased expression:plasma (human) RGD PMID:11525850 RGD:11541048 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779
JBrowse link
G POMC proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2968671 NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706
JBrowse link
G PRKCD protein kinase C delta ISO protein:altered localization:cardiac muscle cell RGD PMID:16990486 RGD:1642547 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15650120 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 treatment ISO RGD PMID:24973766 RGD:9850087 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252
JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 treatment ISO RGD PMID:24973766 RGD:9850087 NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO protein:decreased phosphorylation:heart RGD PMID:14695116 RGD:1643025 NCBI chr17:53,958,807...54,014,752
Ensembl chr17:58,799,069...58,853,653
JBrowse link
G SERPINA1 serpin family A member 1 ISO protein:increased expression:serum RGD PMID:12509927 RGD:1643164 NCBI chr14:75,001,714...75,014,214
Ensembl chr14:94,334,258...94,345,419
JBrowse link
G SERPING1 serpin family G member 1 treatment ISO RGD PMID:22447201 RGD:6903314 NCBI chr11:52,838,502...52,855,781
Ensembl chr11:56,309,686...56,326,639
JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO RGD PMID:17711618 RGD:4889516 NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA, protein:increased expression:hepatocyte RGD PMID:12392283 RGD:730264 NCBI chr17:72,433,206...72,436,500
Ensembl chr17:77,983,389...77,984,066
JBrowse link
G TAC1 tachykinin precursor 1 ISO protein:increased expression:plasma, lung RGD PMID:19797759 RGD:5147812 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389
JBrowse link
G TACR1 tachykinin receptor 1 ISO mRNA:increased expression:lung RGD PMID:18523300 RGD:5147819 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018
JBrowse link
G TFPI tissue factor pathway inhibitor ISO protein:decreased activity:plasma: RGD PMID:15497025 RGD:2313648 NCBI chr2B:74,744,154...74,834,338
Ensembl chr2B:192,541,881...192,581,384
JBrowse link
G TNF tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:18277951 PMID:26152211 RGD:11049530 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO mRNA, protein:increased expression:thymus RGD PMID:18019056 RGD:2290498 NCBI chr 8:22,440,502...22,476,790
Ensembl chr 8:19,378,547...19,414,724
JBrowse link
G UCN urocortin ISO RGD PMID:16125201 RGD:1642782 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669
JBrowse link
G VDAC2 voltage dependent anion channel 2 ISO RGD PMID:23863682 RGD:10003047 NCBI chr10:71,739,395...71,763,835 JBrowse link
Burns, Chemical term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815
JBrowse link
G IL1A interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 Ensembl chr2A:103,193,131...103,230,005 JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22533443 NCBI chr 7:23,415,922...23,420,767 JBrowse link
Cardiotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:33676887 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G BCHE butyrylcholinesterase ISO CTD Direct Evidence: therapeutic CTD PMID:26145887 NCBI chr 3:162,794,184...162,858,574
Ensembl chr 3:170,845,494...170,911,481
JBrowse link
G BMP2 bone morphogenetic protein 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29800642 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CSF1 colony stimulating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32068018 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083
JBrowse link
G HBEGF heparin binding EGF like growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:29305325 NCBI chr 5:135,699,553...135,713,366
Ensembl chr 5:141,816,402...141,830,531
JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:32068018 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO associated with Precursor Cell Lymphoblastic Leukemia-Lymphoma;DNA:polymorphism: :894G>T(human) RGD PMID:26345518 RGD:11533645 NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233
JBrowse link
G NPPB natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 1:10,621,416...10,622,960
Ensembl chr 1:11,838,518...11,839,995
JBrowse link
G NRG1 neuregulin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29305325 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977
JBrowse link
G RAC1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28710503 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RARG retinoic acid receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:26237429 NCBI chr12:35,521,276...35,542,814
Ensembl chr12:36,303,359...36,325,111
JBrowse link
G TLR2 toll like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29959987 PMID:32068018 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30009776 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
carotid artery dissection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor ISO ClinVar Annotator: match by term: Carotid artery dissection ClinVar PMID:1301956 PMID:2088165 PMID:2318961 PMID:3263645 PMID:8882879 More... NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791
JBrowse link
G MYLK myosin light chain kinase ISO ClinVar Annotator: match by term: Carotid artery dissection ClinVar PMID:25326637 PMID:25741868 PMID:28492532 NCBI chr 3:120,711,705...120,983,432
Ensembl chr 3:127,614,173...127,793,261
JBrowse link
Carotid Artery Dissection, Internal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor ISO ClinVar Annotator: match by term: Internal carotid artery dissection ClinVar PMID:1301956 PMID:2088165 PMID:2318961 PMID:3263645 PMID:8882879 More... NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791
JBrowse link
G MYLK myosin light chain kinase ISO ClinVar Annotator: match by term: Internal carotid artery dissection ClinVar PMID:25326637 PMID:25741868 PMID:28492532 NCBI chr 3:120,711,705...120,983,432
Ensembl chr 3:127,614,173...127,793,261