Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Liver Neoplasms
go back to main search page
Accession:DOID:9001586 term browser browse the term
Definition:Experimentally induced tumors of the LIVER.
Synonyms:exact_synonym: Experimental Hepatomas;   Experimental Liver Neoplasm;   Morris Hepatoma;   Novikoff hepatoma;   experimental hepatoma
 primary_id: MESH:D008114
 alt_id: RDO:0006023
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Experimental Liver Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 IDA RGD PMID:15853769 RGD:1598580 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B IEP RGD PMID:8104413 RGD:5684351 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Adsl adenylosuccinate lyase IEP protein:increased activity:liver (rat) RGD PMID:2937404 RGD:1598766 NCBI chr 7:122,157,201...122,192,328
Ensembl chr 7:122,157,201...122,192,328
JBrowse link
G Afp alpha-fetoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24012840 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agps alkylglycerone phosphate synthase IDA RGD PMID:7407223 RGD:1598794 NCBI chr 3:62,648,352...62,749,250
Ensembl chr 3:62,648,447...62,749,153
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Apoa4 apolipoprotein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoc2 apolipoprotein C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Arrb2 arrestin, beta 2 IEP mRNA, protein:increased expression:liver (rat) RGD PMID:21167192 RGD:5509890 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atp7a ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Atp7b ATPase copper transporting beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bbc3 Bcl-2 binding component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:10426811, PMID:28100771 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10426811, PMID:28100771, PMID:22414765 RGD:11353865 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP mRNA, protein:increased expression:liver RGD PMID:18246794 RGD:2293125 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Ca3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP protein:increased activity:liver (rat) RGD PMID:13618893 RGD:5132586 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccnb1 cyclin B1 IEP mRNA:increased expression:liver RGD PMID:17342310 RGD:2315991 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:28100771, PMID:17055752 RGD:2289139 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccndbp1 cyclin D1 binding protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16501603 NCBI chr 3:112,951,065...112,961,620
Ensembl chr 3:112,950,890...112,961,614
JBrowse link
G Cd40lg CD40 ligand ISO RGD PMID:19035311 RGD:5491179 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd63 Cd63 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:3,320,250...3,335,583
Ensembl chr 7:3,320,103...3,335,582
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494, PMID:25319454 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP protein:decreased expression:liver: RGD PMID:8640740 RGD:8662309 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 severity IEP mRNA:decreased expression:liver RGD PMID:3387993 RGD:2303406 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11280770, PMID:20118494, PMID:21147764 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA:increased expression:liver RGD PMID:22687991 RGD:7296954 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11376689, PMID:21147764 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18056438 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) IEP protein:increased activity:liver (rat) RGD PMID:6331524 RGD:5132618 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
G Dtymk deoxythymidylate kinase IEP protein:increased activity:tumor (rat) RGD PMID:6244089 RGD:5133686 NCBI chr 9:100,921,565...100,930,399
Ensembl chr 9:100,921,565...100,930,399
JBrowse link
G Eno2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Ephx1 epoxide hydrolase 1 IEP RGD PMID:7260898 RGD:11252158 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G F12 coagulation factor XII ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30737368 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Foxm1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15082532 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Gjb1 gap junction protein, beta 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18308698, PMID:1336494 RGD:7349398 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjb2 gap junction protein, beta 2 IEP RGD PMID:1336494 RGD:7349398 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Glul glutamate-ammonia ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494, PMID:21147764 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Grp gastrin releasing peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr18:61,563,458...61,576,818
Ensembl chr18:61,563,053...61,576,818
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:2563599, PMID:3124819, PMID:7585603, PMID:20188851, PMID:12016164 RGD:2317823 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G H19 H19, imprinted maternally expressed transcript (non-protein coding) IDA DNA:hypomethylation:promoter RGD PMID:15352122 RGD:1342455 NCBI chr 1:215,744,404...215,747,080 JBrowse link
G Hat1 histone acetyltransferase 1 IEP protein:increased expression:liver RGD PMID:17182829 RGD:2316578 NCBI chr 3:58,022,395...58,070,067
Ensembl chr 3:58,022,238...58,070,068
JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11896611 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:7955063, PMID:20118494, PMID:21147764, PMID:27517622 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IEP protein:increased expression:brainstem, cerebral cortex RGD PMID:17258772 RGD:1624998 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Igf2 insulin-like growth factor 2 treatment IEP RGD PMID:22425635 RGD:10402567 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igf2r insulin-like growth factor 2 receptor IAGP RGD PMID:15057872, PMID:9652747 RGD:2311623, RGD:2311630 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:30737368 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26297436 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insr insulin receptor disease_progression IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:cytoplasm,liver (rat) RGD PMID:15520221 RGD:2306052 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kat6a lysine acetyltransferase 6A IEP protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr16:73,942,669...74,020,750
Ensembl chr16:73,943,455...74,023,005
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8603461 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IEP associated with Diabetes Mellitus, Experimental;protein:increased expression:liver RGD PMID:15520221 RGD:2306052 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:84,165,950...84,166,059
Ensembl chr10:84,165,950...84,166,059
JBrowse link
G Mir125a microRNA 125a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Mir145 microRNA 145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir151 microRNA 151 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:114,485,547...114,485,643 JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr19:25,290,211...25,290,316
Ensembl chr19:25,290,211...25,290,316
JBrowse link
G Mir181d microRNA 181d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr19:25,290,051...25,290,133
Ensembl chr19:25,290,051...25,290,133
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:57,463,569...57,463,678
Ensembl chr 4:57,463,569...57,463,678
JBrowse link
G Mir186 microRNA 186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 2:263,873,759...263,873,844
Ensembl chr 2:263,873,759...263,873,844
JBrowse link
G Mir18a microRNA 18a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr15:100,180,015...100,180,110
Ensembl chr15:100,180,015...100,180,110
JBrowse link
G Mir195 microRNA 195 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:56,845,301...56,845,387
Ensembl chr10:56,845,301...56,845,387
JBrowse link
G Mir196b microRNA 196b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:82,199,056...82,199,140
Ensembl chr 4:82,199,056...82,199,140
JBrowse link
G Mir200b microRNA 200b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir206 microRNA 206 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 9:26,791,764...26,791,847
Ensembl chr 9:26,791,764...26,791,847
JBrowse link
G Mir212 microRNA 212 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:62,014,702...62,014,812
Ensembl chr10:62,014,702...62,014,812
JBrowse link
G Mir221 microRNA 221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mir26a microRNA 26a EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 8:127,714,441...127,714,530
Ensembl chr 8:127,714,441...127,714,530
JBrowse link
G Mir26b microRNA 26b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 9:81,675,275...81,675,359
Ensembl chr 9:81,675,275...81,675,359
JBrowse link
G Mir290 microRNA 290 EXP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:64,538,705...64,538,785
Ensembl chr 1:64,538,705...64,538,785
JBrowse link
G Mir300 microRNA 300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:133,874,152...133,874,230
Ensembl chr 6:133,874,144...133,874,233
JBrowse link
G Mir301a microRNA 301a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:74,417,746...74,417,845
Ensembl chr10:74,417,746...74,417,845
JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mir30b microRNA 30b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:109,282,662...109,282,747
Ensembl chr 7:109,282,658...109,282,752
JBrowse link
G Mir30d microRNA 30d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:109,286,463...109,286,544
Ensembl chr 7:109,286,463...109,286,544
JBrowse link
G Mir30e microRNA 30e ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:139,702,872...139,702,963
Ensembl chr 5:139,702,872...139,702,963
JBrowse link
G Mir324 microRNA 324 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:56,621,126...56,621,208
Ensembl chr10:56,621,124...56,621,212
JBrowse link
G Mir331 microRNA 331 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir336 microRNA 336 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:35,349,756...35,349,851
Ensembl chr10:35,349,756...35,349,851
JBrowse link
G Mir339 microRNA 339 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr12:17,369,002...17,369,097
Ensembl chr12:17,369,002...17,369,097
JBrowse link
G Mir347 microRNA mir-347 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526
G Mir349 microRNA 349 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:130,146,518...130,146,614
Ensembl chr 7:130,146,518...130,146,614
JBrowse link
G Mir34a microRNA 34a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mir352 microRNA mir-352 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526
G Mir383 microRNA 383 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr16:57,519,675...57,519,748
Ensembl chr16:57,519,675...57,519,748
JBrowse link
G Mir409 microRNA 409 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:133,893,419...133,893,495 JBrowse link
G Mir429 microRNA 429 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:173,488,331...173,488,415
Ensembl chr 5:173,488,331...173,488,415
JBrowse link
G Mir598 microRNA 598 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr15:47,057,496...47,057,574
Ensembl chr15:47,057,496...47,057,575
JBrowse link
G Mir652 microRNA 652 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:114,002,534...114,002,614
Ensembl chr  X:114,002,534...114,002,614
JBrowse link
G Mir671 microRNA 671 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:7,108,747...7,108,827
Ensembl chr 4:7,108,738...7,108,835
JBrowse link
G Mir708 microRNA 708 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:161,221,246...161,221,333
Ensembl chr 1:161,221,246...161,221,333
JBrowse link
G Mir760 microRNA 760 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 2:225,873,354...225,873,433
Ensembl chr 2:225,873,354...225,873,433
JBrowse link
G Mir92b microRNA 92b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 2:188,541,034...188,541,116
Ensembl chr 2:188,541,034...188,541,116
JBrowse link
G Mir98 microRNA 98 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:21,583,875...21,583,982
Ensembl chr  X:21,583,875...21,583,982
JBrowse link
G Mir99b microRNA 99b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:59,704,216...59,704,285
Ensembl chr 1:59,704,216...59,704,285
JBrowse link
G Mirlet7b microRNA let-7b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:126,590,627...126,590,711
Ensembl chr 7:126,590,627...126,590,711
JBrowse link
G Mirlet7d microRNA let-7d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr17:16,419,980...16,420,077
Ensembl chr17:16,419,980...16,420,077
JBrowse link
G Mirlet7i microRNA let-7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:66,802,731...66,802,815
Ensembl chr 7:66,802,732...66,802,821
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP
ISO
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression, increased activity:liver
CTD PMID:30603057, PMID:19528495, PMID:19539802 RGD:2325736, RGD:2325734 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP mRNA, protein:increased expression, increased activity:liver RGD PMID:19528495, PMID:19539802 RGD:2325736, RGD:2325734 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpeg1 macrophage expressed 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 1:228,724,559...228,729,054
Ensembl chr 1:228,724,900...228,727,160
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP
ISO
mRNA:increased expression:liver (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:9079223, PMID:11280770, PMID:18560566, PMID:3335218 RGD:10059623 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nos2 nitric oxide synthase 2 IEP protein:increased expression:liver RGD PMID:10383909 RGD:2325277 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 IEP protein:increased expression:liver RGD PMID:18942116 RGD:2325310 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IEP mRNA, protein:increased expression:liver (rat) RGD PMID:27867096 RGD:13442478 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 susceptibility ISO RGD PMID:17283114 RGD:14701032 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17172636, PMID:24769335, PMID:25656644 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO human gene in mouse model RGD PMID:16286660 RGD:14975105 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IEP protein:decreased expression:liver RGD PMID:7929120 RGD:1642378 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Pml PML nuclear body scaffold ISO CTD Direct Evidence: therapeutic CTD PMID:20377131 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:761203 NCBI chr14:33,580,541...33,614,919
Ensembl chr14:33,580,541...33,614,919
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IEP mRNA:increased expression:liver (rat) RGD PMID:2562181 RGD:8693574 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Ptgr1 prostaglandin reductase 1 IEP protein:increased expression:liver RGD PMID:24853774 RGD:14401713 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Rad51 RAD51 recombinase IEP protein:decreased expression:liver RGD PMID:17219426 RGD:2292638 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17854601 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rgn regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rida reactive intermediate imine deaminase A homolog IEP protein:increased expression:liver (rat) RGD PMID:12939504 RGD:9685719 NCBI chr 7:73,256,506...73,270,308
Ensembl chr 7:73,256,508...73,270,308
JBrowse link
G Rras2 RAS related 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 IEP RGD PMID:15224347 RGD:2316863 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688
JBrowse link
G Rxra retinoid X receptor alpha IEP mRNA, protein:decreased expression:liver RGD PMID:17786350 RGD:1643105 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Serpina1 serpin family A member 1 IEP RGD PMID:10569800 RGD:1626391 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Slc31a1 solute carrier family 31 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15197228 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Sox4 SRY-box transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sqle squalene epoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26297436, PMID:28100771 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tek TEK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tgfa transforming growth factor alpha IEP
ISO
protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD PMID:9079223, PMID:16734725 RGD:2317490 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tk1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
Morris hepatoma
CTD PMID:28100771, PMID:9063767 RGD:14696818 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10626228, PMID:28100771 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15833021, PMID:17533171 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Vim vimentin IDA RGD PMID:19199359 RGD:6480440 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xdh xanthine dehydrogenase IEP protein:decreased expression:liver RGD PMID:3460692 RGD:13210515 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16108
    disease of cellular proliferation 5913
      Experimental Neoplasms 602
        Experimental Liver Neoplasms 183
Path 2
Term Annotations click to browse term
  disease 16108
    disease of anatomical entity 15356
      gastrointestinal system disease 4673
        hepatobiliary disease 2486
          liver disease 2394
            Liver Neoplasms 949
              Experimental Liver Neoplasms 183
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.