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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Liver Neoplasms
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Accession:DOID:9001586 term browser browse the term
Definition:Experimentally induced tumors of the LIVER.
Synonyms:exact_synonym: Experimental Hepatomas;   Experimental Liver Neoplasm;   Morris Hepatoma;   Novikoff hepatoma;   experimental hepatoma
 primary_id: MESH:D008114
 alt_id: RDO:0006023
For additional species annotation, visit the Alliance of Genome Resources.



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Experimental Liver Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 ISO RGD PMID:15853769 RGD:1598580 NCBI chr15:75,402,296...75,487,092
Ensembl chr15:75,402,396...75,486,403
JBrowse link
G ADSL adenylosuccinate lyase ISO protein:increased activity:liver (rat) RGD PMID:2937404 RGD:1598766 NCBI chr 5:8,027,799...8,045,480
Ensembl chr 5:8,025,508...8,047,603
JBrowse link
G AFP alpha fetoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24012840 PMID:32961231 NCBI chr 8:69,677,690...69,698,864
Ensembl chr 8:69,677,690...69,698,864
JBrowse link
G AGPS alkylglycerone phosphate synthase ISO RGD PMID:7407223 RGD:1598794 NCBI chr15:83,146,063...83,285,905
Ensembl chr15:83,146,002...83,391,984
JBrowse link
G ALAS2 5'-aminolevulinate synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:47,871,519...47,896,041
Ensembl chr  X:47,871,523...47,896,000
JBrowse link
G APOA4 apolipoprotein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G APOC2 apolipoprotein C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 6:51,404,219...51,406,302 JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression ISO RGD PMID:26569409 RGD:11344640 NCBI chr 6:84,049,729...84,124,302
Ensembl chr 6:84,049,087...84,123,349
JBrowse link
G ARRB2 arrestin beta 2 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:21167192 RGD:5509890 NCBI chr12:52,161,776...52,170,362
Ensembl chr12:52,161,778...52,170,342
JBrowse link
G ATP7A ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048
JBrowse link
G ATP7B ATPase copper transporting beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064
JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BBC3 BCL2 binding component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887
JBrowse link
G BCL2L1 BCL2 like 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:10426811 PMID:22414765 PMID:28100771 RGD:11353865 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO mRNA, protein:increased expression:liver RGD PMID:18246794 RGD:2293125 NCBI chr12:3,747,276...3,755,214
Ensembl chr12:3,747,279...3,755,215
JBrowse link
G CA3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 4:51,227,485...51,237,861
Ensembl chr 4:51,227,485...51,237,844
JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO protein:increased activity:liver (rat) RGD PMID:13618893 RGD:5132586 NCBI chr 3:111,887,017...111,914,511
Ensembl chr 3:111,887,020...111,914,492
JBrowse link
G CCL20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CCNB1 cyclin B1 ISO mRNA:increased expression:liver RGD PMID:17342310 RGD:2315991 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17055752 PMID:28100771 RGD:2289139 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
JBrowse link
G CCNDBP1 cyclin D1 binding protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16501603 NCBI chr 1:128,253,111...128,269,534
Ensembl chr 1:128,253,035...128,269,452
JBrowse link
G CCNG1 cyclin G1 ISO RGD PMID:27982046 RGD:151361200 NCBI chr16:60,349,255...60,356,737
Ensembl chr16:60,349,258...60,356,738
JBrowse link
G CCNG2 cyclin G2 ISO RGD PMID:27982046 RGD:151361200 NCBI chr 8:72,790,394...72,800,553
Ensembl chr 8:72,791,703...72,800,551
JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:19035311 RGD:5491179 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709
JBrowse link
G CD63 CD63 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 5:21,172,275...21,176,225
Ensembl chr 5:21,172,283...21,176,232
JBrowse link
G CDH1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494 PMID:25319454 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:decreased expression:liver: RGD PMID:8640740 RGD:8662309 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:19533683 RGD:2315050 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C disease_progression ISO mRNA:increased expression:liver (rat)
protein:increased expression:liver (rat)
protein:decreased expression:liver (rat)
RGD PMID:3965145 PMID:19533683 PMID:26606000 RGD:11354707 RGD:152998958 RGD:2315050 NCBI chr 2:2,019,391...2,022,092
Ensembl chr 2:2,019,830...2,021,853
JBrowse link
G COPS5 COP9 signalosome subunit 5 ISO protein:increased expression:liver (rat) RGD PMID:26606000 RGD:11354707 NCBI chr 4:67,740,528...67,758,153
Ensembl chr 4:67,739,251...67,758,150
JBrowse link
G CP ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr13:89,396,713...89,463,540
Ensembl chr13:89,396,708...89,463,476
JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 severity ISO mRNA:decreased expression:liver RGD PMID:3387993 RGD:2303406 NCBI chr15:113,210,038...113,339,086
Ensembl chr15:113,150,157...113,339,078
JBrowse link
G CTNNB1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11280770 PMID:20118494 PMID:21147764 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 8:71,665,541...71,670,236
Ensembl chr 8:71,663,501...71,670,271
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA:increased expression:liver RGD PMID:22687991 RGD:7296954 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11376689 PMID:21147764 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18056438 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817
JBrowse link
G CYP2F1 cytochrome P450 family 2 subfamily F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 6:49,014,912...49,032,207
Ensembl chr 6:49,017,008...49,029,388
JBrowse link
G DHODH dihydroorotate dehydrogenase (quinone) ISO protein:increased activity:liver (rat) RGD PMID:6331524 RGD:5132618 NCBI chr 6:14,942,898...14,956,000
Ensembl chr 6:14,942,933...14,955,997
JBrowse link
G DTYMK deoxythymidylate kinase ISO protein:increased activity:tumor (rat) RGD PMID:6244089 RGD:5133686 NCBI chr15:140,248,071...140,255,803
Ensembl chr15:140,248,079...140,255,805
JBrowse link
G ENO2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr 5:63,799,927...63,809,067
Ensembl chr 5:63,799,930...63,809,410
JBrowse link
G EPHX1 epoxide hydrolase 1 ISO RGD PMID:7260898 RGD:11252158 NCBI chr10:13,757,489...13,773,071
Ensembl chr10:13,751,881...13,773,072
JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35044086 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
JBrowse link
G F12 coagulation factor XII ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828
JBrowse link
G FAS Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30737368 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G FOXM1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15082532 NCBI chr 5:67,246,219...67,263,215
Ensembl chr 5:67,245,694...67,263,211
Ensembl chr 5:67,245,694...67,263,211
JBrowse link
G GJB1 gap junction protein beta 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:1336494 PMID:18308698 RGD:7349398 NCBI chr  X:57,241,990...57,249,496
Ensembl chr  X:57,242,045...57,249,885
JBrowse link
G GJB2 gap junction protein beta 2 ISO RGD PMID:1336494 RGD:7349398 NCBI chr11:774,090...781,252
Ensembl chr11:775,166...775,846
JBrowse link
G GLUL glutamate-ammonia ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494 PMID:21147764 NCBI chr 9:123,751,551...123,762,575
Ensembl chr 9:123,751,548...123,762,547
JBrowse link
G GRP gastrin releasing peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr 1:161,708,815...161,721,986
Ensembl chr 1:161,708,812...161,721,782
JBrowse link
G HAT1 histone acetyltransferase 1 ISO protein:increased expression:liver RGD PMID:17182829 RGD:2316578 NCBI chr15:78,022,147...78,079,669
Ensembl chr15:78,022,207...78,079,608
JBrowse link
G HGF hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11896611 NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,438,143...98,513,564
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:7955063 PMID:20118494 PMID:21147764 PMID:27517622 NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G HTR2C 5-hydroxytryptamine receptor 2C ISO protein:increased expression:brainstem, cerebral cortex RGD PMID:17258772 RGD:1624998 NCBI chr  X:94,053,415...94,313,352
Ensembl chr  X:94,053,456...94,313,355
JBrowse link
G IGF2 insulin like growth factor 2 treatment ISO RGD PMID:22425635 RGD:10402567 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO RGD PMID:9652747 PMID:15057872 RGD:2311623 RGD:2311630 NCBI chr 1:7,369,485...7,472,480
Ensembl chr 1:7,368,103...7,472,548
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:30737368 NCBI chr  X:125,035,575...125,056,445
Ensembl chr  X:125,036,508...125,056,453
JBrowse link
G IL6 interleukin 6 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (mouse)
CTD
RGD
PMID:26297436 PMID:26569409 RGD:11344640 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
JBrowse link
G INSR insulin receptor disease_progression ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:cytoplasm,liver (rat) RGD PMID:15520221 RGD:2306052 NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,104
JBrowse link
G JAK2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G KAT6A lysine acetyltransferase 6A ISO protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr17:11,002,818...11,109,974 JBrowse link
G KDR kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336
JBrowse link
G KDSR 3-ketodihydrosphingosine reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10426811 PMID:28100771 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (rat)
CTD
RGD
PMID:8603461 PMID:19533683 RGD:2315050 NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
JBrowse link
G LOC100739163 glutathione S-transferase P-like ISO protein:increased expression:liver (rat) RGD PMID:3965145 PMID:12016164 RGD:152998958 RGD:2317823 NCBI chr 2:4,978,761...4,982,233 JBrowse link
G LOC100739508 glutathione S-transferase P-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:2563599 PMID:3124819 PMID:7585603 PMID:20188851 NCBI chr 2:5,005,498...5,009,247 JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:liver RGD PMID:15520221 RGD:2306052 NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512
JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:54,539,970...54,554,885
Ensembl chr 7:54,539,970...54,571,747
JBrowse link
G MIR10A microRNA mir-10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr12:24,833,644...24,833,723
Ensembl chr12:24,833,627...24,833,730
JBrowse link
G MIR125A microRNA mir-125a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
JBrowse link
G MIR145 microRNA mir-145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 2:150,580,126...150,580,211
Ensembl chr 2:150,580,126...150,580,211
JBrowse link
G MIR151 microRNA mir-151 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:2,849,041...2,849,120
Ensembl chr 4:2,849,038...2,849,130
JBrowse link
G MIR181C microRNA mir-181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 2:65,279,950...65,280,036
Ensembl chr 2:65,279,944...65,280,040
JBrowse link
G MIR183 microRNA mir-183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr18:18,982,269...18,982,338
Ensembl chr18:18,982,269...18,982,338
JBrowse link
G MIR186 microRNA mir-186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:141,943,328...141,943,409
Ensembl chr 6:141,943,328...141,943,409
JBrowse link
G MIR18A microRNA mir-18a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:60,734,791...60,734,882
Ensembl chr11:60,734,791...60,734,882
JBrowse link
G MIR193A microRNA mir-193a ISO miRNA:decreased expression:liver (mouse) RGD PMID:30165047 RGD:153323340 NCBI chr12:43,336,969...43,337,048
Ensembl chr12:43,336,969...43,337,048
JBrowse link
G MIR195 microRNA mir-195 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr12:52,422,039...52,422,118
Ensembl chr12:52,422,039...52,422,118
JBrowse link
G MIR206 microRNA mir-206 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:45,976,293...45,976,372
Ensembl chr 7:45,976,293...45,976,372
JBrowse link
G MIR212 microRNA mir-212 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr12:48,163,054...48,163,135
Ensembl chr12:48,163,046...48,163,145
JBrowse link
G MIR221 microRNA mir-221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:40,571,068...40,571,137
Ensembl chr  X:40,571,068...40,571,137
JBrowse link
G MIR30A microRNA mir-30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:51,412,827...51,412,933
Ensembl chr 1:51,412,827...51,412,933
JBrowse link
G MIR30B microRNA mir-30b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:6,952,794...6,952,869
Ensembl chr 4:6,952,794...6,952,869
JBrowse link
G MIR30D microRNA mir-30d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:6,948,669...6,948,747
Ensembl chr 4:6,948,669...6,948,747
JBrowse link
G MIR30E microRNA mir-30e ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:170,429,841...170,429,920
Ensembl chr 6:170,429,841...170,429,920
JBrowse link
G MIR331 microRNA mir-331 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:88,028,339...88,028,418
Ensembl chr 5:88,028,339...88,028,418
JBrowse link
G MIR335 microRNA mir-335 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr18:18,341,580...18,341,659
Ensembl chr18:18,341,568...18,341,659
JBrowse link
G MIR339-2 microRNA mir-339-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:164,025,972...164,026,057
Ensembl chr 1:164,025,972...164,026,057
JBrowse link
G MIR383 microRNA mir-383 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr17:2,698,041...2,698,122
Ensembl chr17:2,698,041...2,698,122
JBrowse link
G MIR505 microRNA mir-505 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:114,563,942...114,564,021
Ensembl chr  X:114,563,942...114,564,021
JBrowse link
G MIR652 microRNA mir-652 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:90,166,525...90,166,607
Ensembl chr  X:90,166,516...90,166,613
JBrowse link
G MIR671 microRNA mir-671 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr18:5,989,378...5,989,457
Ensembl chr18:5,989,355...5,989,466
JBrowse link
G MIR708 microRNA mir-708 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 9:13,780,171...13,780,250
Ensembl chr 9:13,780,171...13,780,250
JBrowse link
G MIR98 microRNA mir-98 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:46,302,381...46,302,460
Ensembl chr  X:46,302,381...46,302,460
JBrowse link
G MIR99B microRNA mir-99b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:58,332,211...58,332,280
Ensembl chr 6:58,332,205...58,332,284
JBrowse link
G MIRLET7D microRNA let-7d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 3:43,468,501...43,468,596
Ensembl chr 3:43,468,501...43,468,596
JBrowse link
G MIRLET7E microRNA let-7e ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:58,332,042...58,332,121
Ensembl chr 6:58,332,036...58,332,120
JBrowse link
G MIRLET7I microRNA let-7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:27,252,802...27,252,886
Ensembl chr 5:27,252,787...27,252,894
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression, increased activity:liver
RGD
CTD
PMID:19528495 PMID:19539802 PMID:30603057 RGD:2325734 RGD:2325736 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO mRNA, protein:increased expression, increased activity:liver RGD PMID:19528495 PMID:19539802 RGD:2325734 RGD:2325736 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
JBrowse link
G MPEG1 macrophage expressed 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 2:12,194,303...12,196,594
Ensembl chr 2:12,194,327...12,198,351
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (rat)
CTD
RGD
PMID:3335218 PMID:9079223 PMID:11280770 PMID:18560566 RGD:10059623 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078
JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:liver RGD PMID:10383909 RGD:2325277 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
JBrowse link
G NOTCH1 notch receptor 1 ISO protein:increased expression:liver RGD PMID:18942116 RGD:2325310
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:27867096 RGD:13442478 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 susceptibility ISO RGD PMID:17283114 RGD:14701032 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17172636 PMID:24769335 PMID:25656644 NCBI chr 4:89,226,314...89,231,781
Ensembl chr 4:89,226,690...89,236,431
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO human gene in mouse model RGD PMID:16286660 RGD:14975105 NCBI chr 4:105,845,913...105,853,769
Ensembl chr 4:105,845,872...105,858,227
JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO protein:decreased expression:liver RGD PMID:7929120 RGD:1642378 NCBI chr12:60,880,367...60,919,279 JBrowse link
G PLCL1 phospholipase C like 1 disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:19533683 RGD:2315050 NCBI chr15:101,602,336...102,424,225
Ensembl chr15:101,840,806...101,951,106
JBrowse link
G PML PML nuclear body scaffold ISO CTD Direct Evidence: therapeutic CTD PMID:20377131 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105
JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:761203 NCBI chr 8:55,652,194...55,701,077
Ensembl chr 8:55,654,377...55,701,077
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO mRNA:increased expression:liver (rat) RGD PMID:2562181 RGD:8693574 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646
JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr 6:165,847,390...165,859,918
Ensembl chr 6:165,824,395...165,861,442
JBrowse link
G PTGR1 prostaglandin reductase 1 ISO protein:increased expression:liver RGD PMID:24853774 RGD:14401713 NCBI chr 1:252,373,272...252,395,948
Ensembl chr 1:252,373,282...252,395,948
JBrowse link
G RAD51 RAD51 recombinase ISO protein:decreased expression:liver RGD PMID:17219426 RGD:2292638 NCBI chr 1:130,592,414...130,640,326
Ensembl chr 1:130,586,665...130,640,136
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17854601 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690
JBrowse link
G RGN regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,381
JBrowse link
G RIDA reactive intermediate imine deaminase A homolog ISO protein:increased expression:liver (rat) RGD PMID:12939504 RGD:9685719 NCBI chr 4:38,656,270...38,665,863
Ensembl chr 4:38,656,319...38,670,987
JBrowse link
G RRAS2 RAS related 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr 2:44,890,129...44,961,003 JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO RGD PMID:15224347 RGD:2316863 NCBI chr 9:6,026,151...6,065,211
Ensembl chr 9:6,025,073...6,065,143
JBrowse link
G RXRA retinoid X receptor alpha ISO mRNA, protein:decreased expression:liver RGD PMID:17786350 RGD:1643105 NCBI chr 1:273,698,842...273,797,622
Ensembl chr 1:273,705,505...273,797,620
JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:10569800 RGD:1626391 NCBI chr 7:115,604,282...115,616,915
Ensembl chr 7:115,583,043...115,614,645
JBrowse link
G SLC31A1 solute carrier family 31 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr 1:253,868,389...253,893,135
Ensembl chr 1:253,868,332...253,894,449
JBrowse link
G SLC7A5 solute carrier family 7 member 5 ISO mRNA:increased expression:liver RGD PMID:17498859 RGD:151357003 NCBI chr 6:1,545,940...1,574,298
Ensembl chr 6:1,545,944...1,574,285
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15197228 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967
JBrowse link
G SOX4 SRY-box transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr 7:16,886,834...16,895,488
Ensembl chr 7:16,891,319...16,892,752
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340
JBrowse link
G SQLE squalene epoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 4:14,669,789...14,700,152
Ensembl chr 4:14,669,791...14,700,126
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26297436 PMID:28100771 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992
JBrowse link
G TEK TEK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 1:195,938,177...196,052,294
Ensembl chr 1:195,937,432...196,051,980
JBrowse link
G TGFA transforming growth factor alpha ISO protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9079223 PMID:16734725 RGD:2317490 NCBI chr 3:71,948,232...72,054,257
Ensembl chr 3:71,948,137...72,050,474
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046
JBrowse link
G TK1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr12:3,785,997...3,794,824
Ensembl chr12:3,786,031...3,795,917
JBrowse link
G TNF tumor necrosis factor treatment
disease_progression
ISO Morris hepatoma
protein:increased expression:blood serum (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:9063767 PMID:26569409 PMID:28100771 RGD:11344640 RGD:14696818 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10626228 PMID:28100771 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G TSC22D1 TSC22 domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15833021 PMID:17533171 NCBI chr11:22,518,792...22,634,411
Ensembl chr11:22,518,795...22,634,407
JBrowse link
G VIM vimentin ISO RGD PMID:19199359 RGD:6480440 NCBI chr10:43,516,441...43,526,172
Ensembl chr10:43,517,307...43,526,170
JBrowse link
G XDH xanthine dehydrogenase ISO protein:decreased expression:liver RGD PMID:3460692 RGD:13210515 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14500
    disease of cellular proliferation 6828
      Experimental Neoplasms 467
        Experimental Liver Neoplasms 142
Path 2
Term Annotations click to browse term
  disease 14500
    disease of anatomical entity 14224
      gastrointestinal system disease 6002
        hepatobiliary disease 2584
          liver disease 2485
            Liver Neoplasms 1089
              Experimental Liver Neoplasms 142
paths to the root