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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Experimental Liver Neoplasms
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Accession:DOID:9001586 term browser browse the term
Definition:Experimentally induced tumors of the LIVER.
Synonyms:exact_synonym: Experimental Hepatomas;   Experimental Liver Neoplasm;   Morris Hepatoma;   Novikoff hepatoma;   experimental hepatoma
 primary_id: MESH:D008114
 alt_id: RDO:0006023
For additional species annotation, visit the Alliance of Genome Resources.



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Experimental Liver Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 ISO RGD PMID:15853769 RGD:1598580 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,960
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B ISO RGD PMID:8104413 RGD:5684351 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Adsl adenylosuccinate lyase ISO protein:increased activity:liver (rat) RGD PMID:2937404 RGD:1598766 NCBI chr15:80,832,691...80,855,148
Ensembl chr15:80,832,691...80,855,147
JBrowse link
G Afp alpha fetoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24012840 PMID:32961231 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
JBrowse link
G Agps alkylglycerone phosphate synthase ISO RGD PMID:7407223 RGD:1598794 NCBI chr 2:75,662,477...75,761,694
Ensembl chr 2:75,662,521...75,761,694
JBrowse link
G Alas2 aminolevulinic acid synthase 2, erythroid ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:149,330,413...149,353,618
Ensembl chr  X:149,330,371...149,353,634
JBrowse link
G Apoa4 apolipoprotein A-IV ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Apoc2 apolipoprotein C2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:19,405,504...19,411,866
Ensembl chr 7:19,405,504...19,411,866
JBrowse link
G Arid1a AT rich interactive domain 1A (SWI-like) disease_progression IMP RGD PMID:26569409 RGD:11344640 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080
JBrowse link
G Arrb2 arrestin, beta 2 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:21167192 RGD:5509890 NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Atp7b ATPase, Cu++ transporting, beta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr 8:22,482,799...22,550,632
Ensembl chr 8:22,482,801...22,550,321
JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bbc3 BCL2 binding component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 7:16,042,307...16,052,259
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10426811 PMID:28100771 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10426811 PMID:28100771 PMID:22414765 RGD:11353865 NCBI chr 2:152,600,652...152,675,723
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO mRNA, protein:increased expression:liver RGD PMID:18246794 RGD:2293125 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO protein:increased activity:liver (rat) RGD PMID:13618893 RGD:5132586 NCBI chr 5:31,211,964...31,235,823
Ensembl chr 5:31,212,124...31,235,823
JBrowse link
G Car3 carbonic anhydrase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
JBrowse link
G Ccnb1 cyclin B1 ISO mRNA:increased expression:liver RGD PMID:17342310 RGD:2315991 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28100771 PMID:17055752 RGD:2289139 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccndbp1 cyclin D-type binding-protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16501603 NCBI chr 2:120,838,888...120,847,393
Ensembl chr 2:120,838,884...120,847,385
JBrowse link
G Ccng1 cyclin G1 IMP RGD PMID:27982046 RGD:151361200 NCBI chr11:40,639,379...40,646,155
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Ccng2 cyclin G2 IMP RGD PMID:27982046 RGD:151361200 NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090
JBrowse link
G Cd40lg CD40 ligand IMP RGD PMID:19035311 RGD:5491179 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd63 CD63 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr10:128,731,577...128,748,691
Ensembl chr10:128,736,858...128,748,691
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494 PMID:25319454 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) ISO protein:decreased expression:liver: RGD PMID:8640740 RGD:8662309 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:19533683 RGD:2315050 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) disease_progression ISO protein:decreased expression:liver (rat)
protein:increased expression:liver (rat)
mRNA:increased expression:liver (rat)
RGD PMID:26606000 PMID:3965145 PMID:19533683 RGD:11354707, RGD:152998958, RGD:2315050 NCBI chr 7:143,012,076...143,014,802
Ensembl chr 7:143,012,076...143,014,787
JBrowse link
G Cops5 COP9 signalosome subunit 5 ISO protein:increased expression:liver (rat) RGD PMID:26606000 RGD:11354707 NCBI chr 1:10,094,825...10,108,384
Ensembl chr 1:10,094,826...10,108,393
JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
JBrowse link
G Cps1 carbamoyl-phosphate synthetase 1 severity ISO mRNA:decreased expression:liver RGD PMID:3387993 RGD:2303406 NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11280770 PMID:20118494 PMID:21147764 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO mRNA:increased expression:liver RGD PMID:22687991 RGD:7296954 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11376689 PMID:21147764 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr19:39,275,488...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18056438 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
JBrowse link
G Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 5:145,373,119...145,406,550
Ensembl chr 5:145,373,119...145,406,533
JBrowse link
G Dhodh dihydroorotate dehydrogenase ISO protein:increased activity:liver (rat) RGD PMID:6331524 RGD:5132618 NCBI chr 8:110,319,876...110,335,330
Ensembl chr 8:110,317,975...110,335,305
JBrowse link
G Dtymk deoxythymidylate kinase ISO protein:increased activity:tumor (rat) RGD PMID:6244089 RGD:5133686 NCBI chr 1:93,720,298...93,730,246
Ensembl chr 1:93,720,298...93,729,656
JBrowse link
G Eno2 enolase 2, gamma neuronal ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr 6:124,737,016...124,746,636
Ensembl chr 6:124,737,016...124,746,636
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal ISO RGD PMID:7260898 RGD:11252158 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Esr1 estrogen receptor 1 (alpha) ISO CTD Direct Evidence: marker/mechanism CTD PMID:35044086 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G F12 coagulation factor XII (Hageman factor) ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) ISO CTD Direct Evidence: marker/mechanism CTD PMID:30737368 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Foxm1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15082532 NCBI chr 6:128,339,957...128,352,849
Ensembl chr 6:128,339,930...128,353,109
JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18308698 PMID:1336494 RGD:7349398 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235
JBrowse link
G Gjb2 gap junction protein, beta 2 ISO RGD PMID:1336494 RGD:7349398 NCBI chr14:57,336,059...57,342,159
Ensembl chr14:57,336,057...57,342,159
JBrowse link
G Glul glutamate-ammonia ligase (glutamine synthetase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:20118494 PMID:21147764 NCBI chr 1:153,775,675...153,785,469
Ensembl chr 1:153,775,690...153,785,469
JBrowse link
G Grp gastrin releasing peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:2910524 NCBI chr18:66,005,826...66,019,670
Ensembl chr18:66,005,891...66,019,667
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 ISO protein:increased expression:liver (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:2563599 PMID:3124819 PMID:7585603 PMID:20188851 PMID:12016164 More... RGD:2317823, RGD:152998958 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G H19 H19, imprinted maternally expressed transcript ISO DNA:hypomethylation:promoter
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11420682 PMID:15352122 RGD:1342455 NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,131,886
JBrowse link
G Hat1 histone aminotransferase 1 ISO protein:increased expression:liver RGD PMID:17182829 RGD:2316578 NCBI chr 2:71,219,604...71,271,966
Ensembl chr 2:71,219,302...71,271,966
JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11896611 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hras Harvey rat sarcoma virus oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:7955063 PMID:20118494 PMID:21147764 PMID:27517622 NCBI chr 7:140,769,847...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C ISO protein:increased expression:brainstem, cerebral cortex RGD PMID:17258772 RGD:1624998 NCBI chr  X:145,745,509...145,980,273
Ensembl chr  X:145,745,509...145,980,273
JBrowse link
G Igf2 insulin-like growth factor 2 treatment ISO RGD PMID:22425635 RGD:10402567 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553
JBrowse link
G Igf2r insulin-like growth factor 2 receptor ISO RGD PMID:15057872 PMID:9652747 RGD:2311623, RGD:2311630 NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:30737368 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460
JBrowse link
G Il6 interleukin 6 disease_progression ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (mouse)
CTD
RGD
PMID:26297436 PMID:26569409 RGD:11344640 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Insr insulin receptor disease_progression ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:cytoplasm,liver (rat) RGD PMID:15520221 RGD:2306052 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Kat6a K(lysine) acetyltransferase 6A ISO protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr 8:23,349,458...23,433,275
Ensembl chr 8:23,349,551...23,433,275
JBrowse link
G Kdr kinase insert domain protein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 5:76,093,487...76,139,885
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (rat)
CTD
RGD
PMID:8603461 PMID:19533683 RGD:2315050 NCBI chr 6:145,162,425...145,196,144
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 ISO associated with Diabetes Mellitus, Experimental;protein:increased expression:liver RGD PMID:15520221 RGD:2306052 NCBI chr 9:64,093,051...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Met met proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 7:78,783,516...78,798,808
Ensembl chr 7:78,783,516...78,798,808
JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100
JBrowse link
G Mir125a microRNA 125a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr17:18,051,074...18,051,141
Ensembl chr17:18,051,074...18,051,141
JBrowse link
G Mir145a microRNA 145a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965
JBrowse link
G Mir151 microRNA 151 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr15:73,126,664...73,126,731
Ensembl chr15:73,126,664...73,126,731
JBrowse link
G Mir18 microRNA 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr14:115,281,283...115,281,378
Ensembl chr14:115,281,283...115,281,378
JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 8:84,905,502...84,905,590
Ensembl chr 8:84,905,502...84,905,590
JBrowse link
G Mir181d microRNA 181d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 8:84,905,345...84,905,416
Ensembl chr 8:84,905,345...84,905,416
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:30,169,667...30,169,736
Ensembl chr 6:30,169,667...30,169,736
JBrowse link
G Mir186 microRNA 186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 3:157,249,916...157,249,986
Ensembl chr 3:157,249,916...157,249,986
JBrowse link
G Mir193a microRNA 193a IEP miRNA:decreased expression:liver (mouse) RGD PMID:30165047 RGD:153323340 NCBI chr11:79,602,795...79,602,860
Ensembl chr11:79,602,795...79,602,860
JBrowse link
G Mir195a microRNA 195a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:70,125,868...70,125,961
Ensembl chr11:70,125,868...70,125,961
JBrowse link
G Mir196b microRNA 196b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:52,207,061...52,207,145
Ensembl chr 6:52,207,061...52,207,145
JBrowse link
G Mir200b microRNA 200b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:156,140,138...156,140,207
Ensembl chr 4:156,140,138...156,140,207
JBrowse link
G Mir206 microRNA 206 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:20,749,234...20,749,306
Ensembl chr 1:20,749,234...20,749,306
JBrowse link
G Mir207 microRNA 207 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:40,722,917...40,722,995
Ensembl chr 4:40,722,917...40,722,995
JBrowse link
G Mir212 microRNA 212 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:75,064,214...75,064,304
Ensembl chr11:75,064,214...75,064,304
JBrowse link
G Mir221 microRNA 221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:19,012,533...19,012,627
Ensembl chr  X:19,012,533...19,012,627
JBrowse link
G Mir26a-1 microRNA 26a-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953
JBrowse link
G Mir26b microRNA 26b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:74,433,469...74,433,553
Ensembl chr 1:74,433,469...74,433,553
JBrowse link
G Mir292 microRNA 292 EXP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:3,267,863...3,267,944
Ensembl chr 7:3,267,863...3,267,944
JBrowse link
G Mir301 microRNA 301 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:87,003,830...87,003,915
Ensembl chr11:87,003,830...87,003,915
JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420
JBrowse link
G Mir30b microRNA 30b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr15:68,209,264...68,209,359
Ensembl chr15:68,209,264...68,209,359
JBrowse link
G Mir30d microRNA 30d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr15:68,213,057...68,213,138
Ensembl chr15:68,213,057...68,213,138
JBrowse link
G Mir30e microRNA 30e ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:120,629,803...120,629,894
Ensembl chr 4:120,629,803...120,629,894
JBrowse link
G Mir324 microRNA 324 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:69,902,869...69,902,957
Ensembl chr11:69,902,869...69,902,957
JBrowse link
G Mir331 microRNA 331 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:93,799,630...93,799,725
Ensembl chr10:93,799,630...93,799,725
JBrowse link
G Mir335 microRNA 335 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 6:30,741,298...30,741,395
Ensembl chr 6:30,741,298...30,741,395
JBrowse link
G Mir338 microRNA 338 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:119,905,591...119,905,688
Ensembl chr11:119,905,591...119,905,688
JBrowse link
G Mir339 microRNA 339 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:139,355,405...139,355,500
Ensembl chr 5:139,355,405...139,355,500
JBrowse link
G Mir340 microRNA 340 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr11:49,960,529...49,960,626
Ensembl chr11:49,960,529...49,960,626
JBrowse link
G Mir34a microRNA 34a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012
JBrowse link
G Mir350 microRNA 350 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 1:176,599,891...176,599,989
Ensembl chr 1:176,599,891...176,599,989
JBrowse link
G Mir383 microRNA 383 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 8:38,719,287...38,719,356
Ensembl chr 8:38,719,287...38,719,356
JBrowse link
G Mir409 microRNA 409 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr12:109,709,592...109,709,670
Ensembl chr12:109,709,592...109,709,670
JBrowse link
G Mir429 microRNA 429 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:156,138,362...156,138,444
Ensembl chr 4:156,138,362...156,138,444
JBrowse link
G Mir483 microRNA 483 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:142,208,661...142,208,733
Ensembl chr 7:142,208,661...142,208,733
JBrowse link
G Mir505 microRNA 505 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:59,439,649...59,439,738
Ensembl chr  X:59,439,649...59,439,738
JBrowse link
G Mir539 microRNA 539 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr12:109,694,563...109,694,636
Ensembl chr12:109,694,563...109,694,636
JBrowse link
G Mir598 microRNA 598 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr14:63,964,638...63,964,716
Ensembl chr14:63,964,638...63,964,716
JBrowse link
G Mir652 microRNA 652 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:141,521,996...141,522,093
Ensembl chr  X:141,521,996...141,522,093
JBrowse link
G Mir671 microRNA 671 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 5:24,797,112...24,797,209
Ensembl chr 5:24,797,112...24,797,209
JBrowse link
G Mir708 microRNA 708 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 7:95,898,631...95,898,739
Ensembl chr 7:95,898,631...95,898,739
JBrowse link
G Mir760 microRNA 760 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 3:122,087,234...122,087,352
Ensembl chr 3:122,087,234...122,087,352
JBrowse link
G Mir872 microRNA 872 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 4:94,553,394...94,553,474
Ensembl chr 4:94,553,394...94,553,474
JBrowse link
G Mir92b microRNA 92b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr 3:89,134,423...89,134,505
Ensembl chr 3:89,134,423...89,134,505
JBrowse link
G Mir98 microRNA 98 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr  X:150,696,210...150,696,317
Ensembl chr  X:150,696,210...150,696,317
JBrowse link
G Mir99b microRNA 99b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr17:18,050,450...18,050,519
Ensembl chr17:18,050,450...18,050,519
JBrowse link
G Mirlet7b microRNA let7b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr15:85,591,520...85,591,604
Ensembl chr15:85,591,520...85,591,604
JBrowse link
G Mirlet7d microRNA let7d ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr13:48,689,488...48,689,590
Ensembl chr13:48,689,488...48,689,590
JBrowse link
G Mirlet7e microRNA let7e ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr17:18,050,614...18,050,706
Ensembl chr17:18,050,614...18,050,706
JBrowse link
G Mirlet7i microRNA let7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:21035526 NCBI chr10:122,821,545...122,821,629
Ensembl chr10:122,821,545...122,821,629
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression, increased activity:liver
CTD
RGD
PMID:30603057 PMID:19528495 PMID:19539802 RGD:2325736, RGD:2325734 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO mRNA, protein:increased expression, increased activity:liver RGD PMID:19528495 PMID:19539802 RGD:2325736, RGD:2325734 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpeg1 macrophage expressed gene 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr19:12,438,134...12,442,649
Ensembl chr19:12,438,143...12,442,647
JBrowse link
G Myc myelocytomatosis oncogene ISO mRNA:increased expression:liver (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9079223 PMID:11280770 PMID:18560566 PMID:3335218 RGD:10059623 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO protein:increased expression:liver RGD PMID:10383909 RGD:2325277 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notch1 notch 1 ISO protein:increased expression:liver RGD PMID:18942116 RGD:2325310 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 ISO mRNA, protein:increased expression:liver (rat) RGD PMID:27867096 RGD:13442478 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 susceptibility IMP RGD PMID:17283114 RGD:14701032 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17172636 PMID:24769335 PMID:25656644 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nras neuroblastoma ras oncogene ISO human gene in mouse model RGD PMID:16286660 RGD:14975105 NCBI chr 3:102,965,601...102,975,230
Ensembl chr 3:102,965,601...102,975,230
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase ISO protein:decreased expression:liver RGD PMID:7929120 RGD:1642378 NCBI chr11:59,861,440...59,937,394
Ensembl chr11:59,861,440...59,937,315
JBrowse link
G Plcl1 phospholipase C-like 1 disease_progression ISO mRNA:increased expression:liver (rat) RGD PMID:19533683 RGD:2315050 NCBI chr 1:55,442,722...55,793,444
Ensembl chr 1:55,445,080...55,793,444
JBrowse link
G Pml promyelocytic leukemia ISO CTD Direct Evidence: therapeutic CTD PMID:20377131 NCBI chr 9:58,124,462...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:761203 NCBI chr 5:77,061,096...77,099,425
Ensembl chr 5:77,061,096...77,099,425
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform ISO mRNA:increased expression:liver (rat) RGD PMID:2562181 RGD:8693574 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr 4:116,542,796...116,557,197
Ensembl chr 4:116,542,741...116,558,019
JBrowse link
G Ptgr1 prostaglandin reductase 1 ISO protein:increased expression:liver RGD PMID:24853774 RGD:14401713 NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119
JBrowse link
G Rad51 RAD51 recombinase ISO protein:decreased expression:liver RGD PMID:17219426 RGD:2292638 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17854601 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Rbmy RNA binding motif protein, Y chromosome EXP CTD Direct Evidence: marker/mechanism CTD PMID:22073224 NCBI chr  Y:2,830,680...2,841,858
Ensembl chr  Y:2,830,680...2,841,854
JBrowse link
G Rgn regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr  X:20,416,005...20,428,328
Ensembl chr  X:20,416,026...20,428,328
JBrowse link
G Rida reactive intermediate imine deaminase A homolog ISO protein:increased expression:liver (rat) RGD PMID:12939504 RGD:9685719 NCBI chr15:34,484,168...34,495,392
Ensembl chr15:34,484,167...34,495,401
JBrowse link
G Rras2 related RAS viral (r-ras) oncogene 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr 7:113,646,017...113,717,016
Ensembl chr 7:113,646,017...113,717,016
JBrowse link
G Rrm1 ribonucleotide reductase M1 ISO RGD PMID:15224347 RGD:2316863 NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978
JBrowse link
G Rxra retinoid X receptor alpha ISO mRNA, protein:decreased expression:liver RGD PMID:17786350 RGD:1643105 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Slc31a1 solute carrier family 31, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23792645 NCBI chr 4:62,278,821...62,310,006
Ensembl chr 4:62,278,964...62,310,006
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 ISO mRNA:increased expression:liver RGD PMID:17498859 RGD:151357003 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15197228 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
JBrowse link
G Sox4 SRY (sex determining region Y)-box 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21147764 NCBI chr13:29,132,902...29,137,682
Ensembl chr13:29,132,902...29,137,696
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Sqle squalene epoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26297436 PMID:28100771 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tek TEK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11956651 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
JBrowse link
G Tgfa transforming growth factor alpha ISO protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9079223 PMID:16734725 RGD:2317490 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28100771 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tk1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11420682 NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918
JBrowse link
G Tnf tumor necrosis factor disease_progression
treatment
ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (mouse)
Morris hepatoma
CTD
RGD
PMID:28100771 PMID:26569409 PMID:9063767 RGD:11344640, RGD:14696818 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trp53 transformation related protein 53 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:10626228 PMID:28100771 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15833021 PMID:17533171 NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
JBrowse link
G Vim vimentin ISO RGD PMID:19199359 RGD:6480440 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Xdh xanthine dehydrogenase ISO protein:decreased expression:liver RGD PMID:3460692 RGD:13210515 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15290
    disease of cellular proliferation 7157
      Experimental Neoplasms 520
        Experimental Liver Neoplasms 168
Path 2
Term Annotations click to browse term
  disease 15290
    disease of anatomical entity 14943
      gastrointestinal system disease 6312
        hepatobiliary disease 2758
          liver disease 2647
            Liver Neoplasms 1155
              Experimental Liver Neoplasms 168
paths to the root