Experimental Liver Cirrhosis - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	Experimental Liver Cirrhosis	go back to main search page
Accession:	DOID:9001573	browse the term
Definition:	Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.
Synonyms:	exact_synonym:	Experimental Hepatic Cirrhosis; Experimental Hepatic Fibrosis; Experimental Liver Cirrhoses
	primary_id:	MESH:D008106
	alt_id:	RDO:0006022

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Rat (911) Mouse (918) Human (909) Chinchilla (815) Bonobo (879) Dog (874) Squirrel (824) Pig (878) Green Monkey (869) Naked Mole-rat (826) All
Genes (879)

Experimental Liver Cirrhosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:148,820,706...148,853,422
Ensembl chr 3:156,408,950...156,423,847

G

aminoadipate aminotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:162,283,569...162,313,720
Ensembl chr 4:174,353,766...174,383,471

G

4-aminobutyrate aminotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420

G

ATP binding cassette subfamily B member 1

CTD Direct Evidence: marker/mechanism

PMID:16182555 PMID:17072980

NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238

G

ATP binding cassette subfamily C member 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:96,385,534...96,458,571
Ensembl chr10:99,889,160...99,947,270

G

ATP binding cassette subfamily C member 5

CTD Direct Evidence: marker/mechanism

NCBI chr 3:180,956,139...181,054,112
Ensembl chr 3:189,122,590...189,219,492

G

ATP binding cassette subfamily G member 1

CTD Direct Evidence: marker/mechanism

NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050

G

ATP binding cassette subfamily G member 5

CTD Direct Evidence: marker/mechanism

NCBI chr2A:43,896,188...43,922,756
Ensembl chr2A:44,745,183...44,771,012

G

ATP binding cassette subfamily G member 8

CTD Direct Evidence: marker/mechanism

NCBI chr2A:43,922,787...43,966,678
Ensembl chr2A:44,771,247...44,904,830

G

actin binding LIM protein family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:144,568,394...144,686,983
Ensembl chr 5:150,576,604...150,697,271

G

acetyl-CoA acetyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787

G

acyl-CoA binding domain containing 4

CTD Direct Evidence: marker/mechanism

NCBI chr17:12,183,444...12,194,687
Ensembl chr17:12,359,577...12,371,106

G

angiotensin I converting enzyme

severity

mRNA:increased expression:liver (rat)
protein:increased activity:plasma (human)
mRNA: increased expression:liver (rat)

PMID:8445218 PMID:19424597 PMID:23663763 PMID:24035938

RGD:21408579 RGD:25671449 RGD:25671457 RGD:25671458

NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853

G

angiotensin converting enzyme 2

protein:increased expression:liver
mRNA, protein:increased expression, increased activity:liver (rat)

PMID:16166274 PMID:19793108

RGD:2316776 RGD:40818265

NCBI chr X:8,189,267...8,229,415
Ensembl chr X:15,470,896...15,510,891

G

acetylcholinesterase (Yt blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184

G

atypical chemokine receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chr2B:123,795,664...123,810,067
Ensembl chr2B:242,666,173...242,667,261

G

acyl-CoA thioesterase 9

CTD Direct Evidence: marker/mechanism

NCBI chr X:16,300,116...16,365,713
Ensembl chr X:23,676,669...23,717,092

G

acyl-CoA oxidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:58,442,532...58,474,601
Ensembl chr 3:59,852,771...59,884,548

G

acid phosphatase 5, tartrate resistant

CTD Direct Evidence: marker/mechanism

NCBI chr19:11,120,451...11,125,167
Ensembl chr19:11,832,575...11,835,203

G

acyl-CoA synthetase long chain family member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:176,920,811...176,991,495
Ensembl chr 4:189,145,403...189,198,646

G

actin alpha 2, smooth muscle

CTD Direct Evidence: marker/mechanism
associated with Schistosomiasis Japonica; mRNA:increased expression:liver (rat)

PMID:26435214 PMID:26739621 PMID:29323718

NCBI chr10:85,660,983...85,678,729
Ensembl chr10:89,164,344...89,182,080

G

actinin alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:49,460,390...49,565,986
Ensembl chr14:68,335,694...68,440,836

G

activin A receptor type 2A

mRNA:decreased expression:liver

NCBI chr2B:11,933,683...12,020,287
Ensembl chr2B:152,253,826...152,288,385

G

adenosine deaminase

CTD Direct Evidence: marker/mechanism

NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868

G

ADAM metallopeptidase domain 17

CTD Direct Evidence: marker/mechanism

NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054

G

adducin 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:106,597,693...106,727,494
Ensembl chr10:110,123,270...110,178,671

G

adhesion G protein-coupled receptor E1

CTD Direct Evidence: marker/mechanism

NCBI chr19:5,918,097...5,970,069
Ensembl chr19:6,838,787...6,891,292

G

alcohol dehydrogenase 4 (class II), pi polypeptide

CTD Direct Evidence: marker/mechanism

NCBI chr 4:91,522,444...91,543,086
Ensembl chr 4:102,183,956...102,206,923

G

alcohol dehydrogenase iron containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:62,975,711...63,012,102
Ensembl chr 8:64,642,062...64,678,306

G

adiponectin, C1Q and collagen domain containing

CTD Direct Evidence: therapeutic

NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885

G

adiponectin receptor 2

severity

NCBI chr12:1,772,426...1,902,070
Ensembl chr12:1,817,620...1,852,251

G

adrenomedullin

protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism

PMID:15370692 PMID:16610064 PMID:16713642

NCBI chr11:10,437,712...10,440,053
Ensembl chr11:10,165,418...10,167,842

G

adenosine A2a receptor

CTD Direct Evidence: marker/mechanism

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

G

adrenoceptor alpha 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 5:155,307,148...155,363,785
Ensembl chr 5:161,923,895...161,979,461

G

adrenoceptor beta 1

mRNA, protein:increased expression:liver

NCBI chr10:110,642,491...110,646,595

G

adrenoceptor beta 2

mRNA, protein:increased expression:liver

NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892

G

adrenoceptor beta 3

mRNA, protein:increased expression:liver

NCBI chr 8:37,263,730...37,267,475
Ensembl chr 8:34,441,311...34,443,949

G

apoptosis enhancing nuclease

CTD Direct Evidence: marker/mechanism

NCBI chr15:67,237,871...67,321,808
Ensembl chr15:86,518,204...86,529,579

G

afamin

CTD Direct Evidence: marker/mechanism

NCBI chr 4:50,691,556...50,714,140
Ensembl chr 4:56,519,389...56,545,974

G

alpha fetoprotein

treatment

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:30346985

NCBI chr 4:50,739,197...50,758,459
Ensembl chr 4:56,571,519...56,590,391

G

ArfGAP with FG repeats 1

CTD Direct Evidence: marker/mechanism

NCBI chr2B:114,711,697...114,800,680
Ensembl chr2B:233,542,185...233,604,897

G

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:102,506,234...102,580,183
Ensembl chr 1:101,226,120...101,299,511

G

angiotensinogen

CTD Direct Evidence: marker/mechanism

NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044

G

AHNAK nucleoprotein

CTD Direct Evidence: marker/mechanism

NCBI chr11:57,791,927...57,904,277
Ensembl chr11:61,149,485...61,249,137

G

axin interactor, dorsalization associated

CTD Direct Evidence: marker/mechanism

NCBI chr 1:198,341,375...198,385,682

G

allograft inflammatory factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:31,276,215...31,278,051
Ensembl chr 6:32,166,301...32,168,125

G

aldo-keto reductase family 1 member B

CTD Direct Evidence: marker/mechanism

NCBI chr 7:126,400,861...126,417,756
Ensembl chr 7:138,912,953...138,924,095

G

aldo-keto reductase family 1 member C3

CTD Direct Evidence: marker/mechanism

NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812

G

AKT interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr16:33,731,652...33,743,571
Ensembl chr16:52,815,559...52,827,750

G

albumin

treatment

CTD Direct Evidence: marker/mechanism

PMID:16642209 PMID:17963606 PMID:21163135 PMID:30346985

NCBI chr 4:50,773,244...50,790,474
Ensembl chr 4:56,605,322...56,622,418

G

aldehyde dehydrogenase 1 family member A1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:51,737,305...51,916,648
Ensembl chr 9:71,680,890...71,814,085

G

aldehyde dehydrogenase 1 family member B1

CTD Direct Evidence: marker/mechanism

PMID:15650968 PMID:25380136

NCBI chr 9:38,239,413...38,244,751
Ensembl chr 9:39,164,392...39,165,945

G

aldehyde dehydrogenase 1 family member L1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:123,166,630...123,244,257
Ensembl chr 3:130,484,862...130,562,934

G

aldehyde dehydrogenase 1 family member L2

CTD Direct Evidence: marker/mechanism

NCBI chr12:102,596,881...102,661,617
Ensembl chr12:105,997,045...106,056,607

G

aldehyde dehydrogenase 2 family member

CTD Direct Evidence: marker/mechanism

NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471

G

alpha-methylacyl-CoA racemase

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 5:76,336,631...76,358,724
Ensembl chr 5:81,687,891...81,742,003

G

angiopoietin 1

disease_progression

protein:increased expression:liver

NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783

G

angiopoietin 2

mRNA, protein:increased expression:multiple organs (rat)

NCBI chr 8:718,367...782,534
Ensembl chr 8:6,506,014...6,566,915

G

angiopoietin like 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:61,855,870...61,863,476
Ensembl chr 1:63,670,516...63,679,194

G

anoctamin 6

CTD Direct Evidence: marker/mechanism

NCBI chr12:43,295,928...43,512,073
Ensembl chr12:44,164,375...44,303,259

G

acidic nuclear phosphoprotein 32 family member A

treatment

NCBI chr15:47,736,770...47,778,763
Ensembl chr15:66,502,285...66,511,637

G

annexin A1

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver

PMID:8755646 PMID:25380136

NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779

G

annexin A2

CTD Direct Evidence: marker/mechanism

NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250

G

annexin A3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:45,585,873...45,644,783
Ensembl chr 4:51,432,846...51,491,677

G

annexin A4

CTD Direct Evidence: marker/mechanism

NCBI chr2A:69,686,651...69,869,340
Ensembl chr2A:70,902,260...70,986,917

G

annexin A5

CTD Direct Evidence: marker/mechanism

NCBI chr 4:113,868,218...113,897,243
Ensembl chr 4:125,006,038...125,034,972

G

adaptor related protein complex 1 subunit sigma 2

CTD Direct Evidence: marker/mechanism

NCBI chr X:8,449,885...8,478,932
Ensembl chr X:15,807,476...15,836,172

G

adaptor related protein complex 3 subunit sigma 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:111,195,900...111,268,129
Ensembl chr 5:116,992,049...117,063,727

G

apoptotic peptidase activating factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939

G

amyloid beta precursor protein binding family B member 1 interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr10:26,613,897...26,740,670
Ensembl chr10:27,030,218...27,104,483

G

adipocyte plasma membrane associated protein

CTD Direct Evidence: marker/mechanism

NCBI chr20:24,903,723...24,933,173
Ensembl chr20:25,251,073...25,280,938

G

apolipoprotein A1

NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122

G

apolipoprotein A4

CTD Direct Evidence: marker/mechanism

NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382

G

apolipoprotein B mRNA editing enzyme catalytic subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:7,777,734...7,793,960
Ensembl chr12:7,939,262...7,944,203

G

amyloid beta precursor protein

CTD Direct Evidence: marker/mechanism

NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:57,161,299...57,206,672
Ensembl chr 3:58,370,430...58,415,258

G

aquaporin 7

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 9:33,160,982...33,180,638

G

arginase 1

mRNA, protein:decreased expression:liver (rat)

NCBI chr 6:129,372,747...129,383,880
Ensembl chr 6:133,479,966...133,491,162

G

arginase 2

mRNA, protein:increased expression:liver

NCBI chr14:48,197,831...48,231,829
Ensembl chr14:67,075,941...67,109,962

G

Rho GTPase activating protein 30

CTD Direct Evidence: marker/mechanism

NCBI chr 1:136,459,485...136,482,384
Ensembl chr 1:140,372,824...140,395,323

G

Rho GTPase activating protein 9

CTD Direct Evidence: marker/mechanism

NCBI chr12:31,445,732...31,453,763
Ensembl chr12:31,693,309...31,710,064

G

Rho GDP dissociation inhibitor beta

CTD Direct Evidence: marker/mechanism

NCBI chr12:14,944,746...14,964,357
Ensembl chr12:15,341,491...15,361,160

G

ADP ribosylation factor like GTPase 11

CTD Direct Evidence: marker/mechanism

NCBI chr13:30,767,431...30,770,962
Ensembl chr13:49,518,030...49,518,620

G

ADP ribosylation factor like GTPase 8A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:177,731,381...177,742,688
Ensembl chr 1:182,033,376...182,045,145

G

armadillo repeat containing X-linked 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:90,750,878...90,755,066

G

actin related protein 2/3 complex subunit 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 7:91,348,120...91,368,299
Ensembl chr 7:104,861,582...104,870,369

G

arrestin beta 2

CTD Direct Evidence: marker/mechanism
protein:increased expression:aorta

PMID:17256744 PMID:25380136

NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517

G

N-acylsphingosine amidohydrolase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:17,272,632...17,300,902

G

asparagine synthetase (glutamine-hydrolyzing)

CTD Direct Evidence: marker/mechanism

NCBI chr 7:89,811,363...89,831,733
Ensembl chr 7:103,392,540...103,413,046

G

asporin

CTD Direct Evidence: marker/mechanism

NCBI chr 9:63,579,188...63,605,811
Ensembl chr 9:91,651,629...91,677,969

G

argininosuccinate synthase 1

mRNA:decreased expression:liver (rat)

NCBI chr 9:101,569,442...101,625,899
Ensembl chr 9:130,219,993...130,276,036

G

activating transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:188,176,728...188,188,842
Ensembl chr 1:193,036,793...193,049,150

G

ATPase phospholipid transporting 10D (putative)

CTD Direct Evidence: marker/mechanism

NCBI chr 4:74,556,104...74,668,218
Ensembl chr 4:85,287,676...85,399,406

G

ATPase H+ transporting V1 subunit D

CTD Direct Evidence: marker/mechanism

NCBI chr14:47,913,254...47,935,376

G

attractin

CTD Direct Evidence: marker/mechanism

NCBI chr20:3,556,445...3,733,322
Ensembl chr20:3,315,278...3,486,628

G

AXL receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr19:38,211,555...38,254,464
Ensembl chr19:46,719,615...46,761,747

G

beta-2-microglobulin

protein:increased expression:urine

NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991

G

beta-1,4-galactosyltransferase 5

CTD Direct Evidence: marker/mechanism

NCBI chr20:45,977,801...46,058,429
Ensembl chr20:47,041,469...47,123,214

G

B9 domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:31,735,065...31,779,454
Ensembl chr17:36,914,969...36,941,391

G

BCL2 antagonist/killer 1

mRNA:increased expression:liver

NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211

G

gamma-butyrobetaine hydroxylase 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:26,995,120...27,083,832
Ensembl chr11:26,898,529...26,986,705

G

BCL2 apoptosis regulator

treatment

mRNA:increased expression:liver (rat)

PMID:17938867 PMID:24218972

RGD:10054116 RGD:2293129

NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100

G

BCR activator of RhoGEF and GTPase

CTD Direct Evidence: marker/mechanism

G

3-hydroxybutyrate dehydrogenase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 3:194,917,904...194,979,451
Ensembl chr 3:204,797,757...204,863,889

G

biglycan

CTD Direct Evidence: marker/mechanism

NCBI chr X:143,045,298...143,059,892
Ensembl chr X:152,931,608...152,946,292

G

BICD cargo adaptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:63,834,515...63,890,904
Ensembl chr 9:91,909,771...91,959,131

G

baculoviral IAP repeat containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:97,269,778...97,290,112
Ensembl chr11:100,763,274...100,785,194

G

baculoviral IAP repeat containing 5

NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159

G

biogenesis of lysosomal organelles complex 1 subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:96,878,280...96,887,830
Ensembl chr10:100,358,095...100,368,640

G

biliverdin reductase A

CTD Direct Evidence: marker/mechanism

NCBI chr 7:40,444,095...40,492,972
Ensembl chr 7:40,489,360...40,526,132

G

Bcl2 modifying factor

CTD Direct Evidence: marker/mechanism

NCBI chr15:19,026,053...19,047,008
Ensembl chr15:37,281,655...37,302,075

G

bone morphogenetic protein 4

mRNA, protein:increased expression:liver

NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752

G

bone morphogenetic protein 7

CTD Direct Evidence: therapeutic

NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021

G

chromosome 1 C1orf21 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr 1:159,915,683...160,157,087
Ensembl chr 1:164,162,395...164,303,139

G

chromosome 1 C1orf210 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr 1:42,583,297...42,587,987
Ensembl chr 1:43,960,676...43,964,384

G

complement C1q A chain

CTD Direct Evidence: marker/mechanism

NCBI chr 1:21,821,927...21,825,020

G

complement C1q B chain

CTD Direct Evidence: marker/mechanism

NCBI chr 1:21,838,514...21,846,855
Ensembl chr 1:22,786,685...22,797,581

G

complement C1q C chain

CTD Direct Evidence: marker/mechanism

NCBI chr 1:21,828,969...21,833,518
Ensembl chr 1:22,770,582...22,782,176

G

chromosome 2 C3orf70 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr 3:182,115,285...182,190,975

G

complement C5a receptor 1

treatment

CTD Direct Evidence: marker/mechanism

PMID:15995705 PMID:25380136

NCBI chr19:44,293,612...44,310,430
Ensembl chr19:52,950,317...52,966,146

G

complement C7

CTD Direct Evidence: marker/mechanism

NCBI chr 5:69,405,041...69,478,445
Ensembl chr 5:74,447,559...74,520,649

G

complement C8 gamma chain

CTD Direct Evidence: marker/mechanism

NCBI chr 9:108,003,376...108,005,648
Ensembl chr 9:136,974,556...136,976,152

G

chromosome 9 C11orf54 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr11:88,763,232...88,785,075
Ensembl chr11:92,250,482...92,272,026

G

carbonic anhydrase 3

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 8:81,965,041...81,976,133

G

carbonic anhydrase 5A

CTD Direct Evidence: marker/mechanism

NCBI chr16:68,564,400...68,618,614

G

calcium/calmodulin dependent protein kinase II delta

CTD Direct Evidence: marker/mechanism

NCBI chr 4:105,957,773...106,271,887
Ensembl chr 4:116,523,850...116,835,387

G

capping actin protein, gelsolin like

CTD Direct Evidence: marker/mechanism

NCBI chr2A:85,447,296...85,466,677
Ensembl chr2A:86,997,891...87,016,263

G

caspase 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149

G

caspase 4

CTD Direct Evidence: marker/mechanism

NCBI chr11:99,883,353...99,909,185
Ensembl chr11:103,366,138...103,391,824

G

caspase 7

CTD Direct Evidence: marker/mechanism

NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626

G

caveolin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655

G

coiled-coil domain containing 126

CTD Direct Evidence: marker/mechanism

NCBI chr 7:24,278,808...24,323,605
Ensembl chr 7:23,884,546...23,927,778

G

C-C motif chemokine ligand 15

CTD Direct Evidence: marker/mechanism

NCBI chr17:20,793,702...20,809,383
Ensembl chr17:21,089,791...21,095,047

G

C-C motif chemokine ligand 2

treatment

CTD Direct Evidence: marker/mechanism

PMID:15492853 PMID:19144177 PMID:28437891

RGD:14995945 RGD:2307001 RGD:8549576

NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384

G

C-C motif chemokine ligand 5

treatment
disease_progression
severity

CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:liver

PMID:20978355 PMID:22574195 PMID:25380136 PMID:25617348

RGD:14995328 RGD:14995329 RGD:14995337

NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172

G

cellular communication network factor 2

mRNA:increased expression:liver (rat)
CTD Direct Evidence: marker/mechanism

PMID:19856102 PMID:25380136

NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077

G

cellular communication network factor 4

NCBI chr 8:129,842,580...129,884,528
Ensembl chr 8:132,818,397...132,858,861

G

cyclin A2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:114,016,917...114,024,816
Ensembl chr 4:125,153,810...125,161,302

G

cyclin B2

CTD Direct Evidence: marker/mechanism

NCBI chr15:38,075,106...38,095,699
Ensembl chr15:56,382,391...56,402,299

G

cyclin G1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:158,814,563...158,822,019
Ensembl chr 5:165,592,971...165,598,728

G

C-C motif chemokine receptor 5

treatment

mRNA,protein:increased expression:liver

NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379

G

CD163 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr12:7,616,714...7,649,768
Ensembl chr12:7,775,343...7,810,023

G

CD276 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr15:52,594,719...52,625,047

G

CD36 molecule (CD36 blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865

G

CD38 molecule

mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:16343077 PMID:25380136

NCBI chr 4:10,228,803...10,295,129
Ensembl chr 4:15,525,835...15,587,677

G

CD48 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 1:136,034,278...136,067,533
Ensembl chr 1:139,956,862...139,990,082

G

CD53 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 1:113,517,715...113,546,466
Ensembl chr 1:126,799,910...126,826,714

G

CD5 molecule like

CTD Direct Evidence: marker/mechanism

NCBI chr 1:133,192,387...133,203,293
Ensembl chr 1:136,985,701...136,996,263

G

CD63 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr12:33,181,896...33,186,123
Ensembl chr12:33,906,314...33,910,595

G

CD68 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr17:7,610,725...7,613,696
Ensembl chr17:7,596,947...7,599,981

G

CD7 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,724,313...76,727,998
Ensembl chr17:82,535,558...82,537,847

G

CD74 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334

G

CD83 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 6:13,961,342...13,980,686
Ensembl chr 6:14,330,752...14,349,946

G

CD86 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 3:119,151,884...119,217,641
Ensembl chr 3:126,059,008...126,124,339

G

CDC42 small effector 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:126,400,094...126,408,769
Ensembl chr 1:130,047,765...130,056,447

G

cadherin 1

associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)

NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488

G

cadherin 5

CTD Direct Evidence: marker/mechanism

NCBI chr16:46,684,545...46,722,740
Ensembl chr16:65,787,370...65,825,360

G

cyclin dependent kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434

G

cyclin dependent kinase 2

NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945

G

cyclin dependent kinase 4

NCBI chr12:31,174,446...31,178,597
Ensembl chr12:31,434,594...31,438,876

G

cyclin dependent kinase inhibitor 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599

G

CDKN2A interacting protein N-terminal like

CTD Direct Evidence: marker/mechanism

NCBI chr 5:129,805,422...129,814,950
Ensembl chr 5:135,955,821...135,964,328

G

cyclin dependent kinase inhibitor 3

CTD Direct Evidence: marker/mechanism

NCBI chr14:34,984,819...35,008,807
Ensembl chr14:53,263,584...53,287,113

G

cysteine dioxygenase type 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:111,159,041...111,170,965
Ensembl chr 5:116,955,295...116,967,506

G

CCAAT enhancer binding protein delta

CTD Direct Evidence: marker/mechanism

NCBI chr 8:44,167,256...44,168,545

G

chymotrypsin like elastase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr12:37,407,189...37,425,684
Ensembl chr12:38,292,562...38,310,197

G

CUGBP Elav-like family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:10,478,500...11,346,255
Ensembl chr10:10,793,682...11,330,504

G

cell migration inducing hyaluronidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:53,044,517...53,129,875
Ensembl chr 9:70,428,899...70,493,952

G

ceramide kinase

CTD Direct Evidence: marker/mechanism

NCBI chr22:26,849,865...26,905,545
Ensembl chr22:45,749,887...45,786,570

G

carboxylesterase 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:47,249,672...47,262,495
Ensembl chr16:66,352,751...66,365,348

G

carboxylesterase 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:47,292,042...47,340,670

G

complement factor D

CTD Direct Evidence: marker/mechanism

G

complement factor properdin

CTD Direct Evidence: marker/mechanism

NCBI chr X:40,060,106...40,066,720
Ensembl chr X:47,956,191...47,961,965

G

chondroitin sulfate synthase 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:79,901,340...79,976,067
Ensembl chr15:99,186,705...99,260,591

G

cell death inducing DFFA like effector a

CTD Direct Evidence: marker/mechanism

NCBI chr18:2,051,880...2,075,909

G

chemokine like factor

CTD Direct Evidence: marker/mechanism

NCBI chr16:46,870,637...46,884,165
Ensembl chr16:65,972,218...65,998,677

G

C-type lectin domain family 4 member A

CTD Direct Evidence: marker/mechanism

NCBI chr12:8,242,240...8,257,860
Ensembl chr12:8,285,174...8,300,029

G

C-type lectin domain family 4 member F

CTD Direct Evidence: marker/mechanism

NCBI chr2A:70,872,242...70,883,547
Ensembl chr2A:71,985,814...71,997,123

G

chloride intracellular channel 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:31,391,958...31,397,920
Ensembl chr 6:32,280,645...32,286,621

G

chloride intracellular channel 2

CTD Direct Evidence: marker/mechanism

NCBI chr X:144,742,839...144,851,524
Ensembl chr X:154,581,649...154,641,515

G

cleavage factor polyribonucleotide kinase subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:52,898,181...52,902,656
Ensembl chr11:56,368,433...56,373,129

G

CKLF like MARVEL transmembrane domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:46,920,341...46,930,047
Ensembl chr16:66,022,698...66,031,525

G

carnosine dipeptidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:67,920,453...67,982,843
Ensembl chr18:71,162,331...71,188,879
Ensembl chr18:71,162,331...71,188,879

G

2',3'-cyclic nucleotide 3' phosphodiesterase

CTD Direct Evidence: marker/mechanism

NCBI chr17:15,338,085...15,349,089
Ensembl chr17:15,560,056...15,568,916

G

canopy FGF signaling regulator 4

CTD Direct Evidence: marker/mechanism

NCBI chr 7:92,154,844...92,162,151
Ensembl chr 7:105,588,007...105,593,864

G

cannabinoid receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:86,017,141...86,044,889

G

collagen type XII alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 6:72,927,897...73,049,168
Ensembl chr 6:76,219,319...76,340,496

G

collagen type I alpha 1 chain

treatment

CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (rat)

PMID:16009107 PMID:20818932 PMID:22706148 PMID:23958495 PMID:25380136 More...

RGD:151665755 RGD:1601595 RGD:5688339 RGD:8552710 RGD:8552768

NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677

G

collagen type I alpha 2 chain

CTD Direct Evidence: marker/mechanism

PMID:7512265 PMID:25380136

NCBI chr 7:86,344,657...86,381,282
Ensembl chr 7:99,935,185...99,971,803

G

collagen type III alpha 1 chain

CTD Direct Evidence: marker/mechanism

PMID:11788567 PMID:25380136

NCBI chr2B:76,285,115...76,322,703
Ensembl chr2B:194,204,613...194,242,956

G

collagen type IV alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr13:91,282,617...91,440,187
Ensembl chr13:110,407,009...110,562,529

G

collagen type IV alpha 2 chain

CTD Direct Evidence: marker/mechanism

NCBI chr13:91,440,314...91,650,138
Ensembl chr13:110,563,119...110,767,530

G

collagen type V alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 9:105,746,388...105,956,280
Ensembl chr 9:134,342,955...134,544,651

G

collagen type V alpha 2 chain

CTD Direct Evidence: marker/mechanism

NCBI chr2B:76,339,756...76,487,133
Ensembl chr2B:194,259,316...194,407,237

G

collagen type VI alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr21:32,322,185...32,346,850
Ensembl chr21:45,584,096...45,607,240

G

collagen type VI alpha 2 chain

CTD Direct Evidence: marker/mechanism
Protein:increased expression:liver

PMID:7791542 PMID:25380136

NCBI chr21:32,442,859...32,478,076
Ensembl chr21:45,710,491...45,730,895

G

collectin subfamily member 12

CTD Direct Evidence: marker/mechanism

NCBI chr18:13,819,575...14,001,383
Ensembl chr18:17,461,678...17,640,721

G

coenzyme Q10A

CTD Direct Evidence: marker/mechanism

NCBI chr12:32,644,452...32,648,804
Ensembl chr12:32,896,587...32,900,572

G

coactosin like F-actin binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:65,231,112...65,284,079
Ensembl chr16:84,572,816...84,625,177

G

carboxypeptidase Q

CTD Direct Evidence: marker/mechanism

NCBI chr 8:93,264,536...93,883,201
Ensembl chr 8:95,599,177...95,974,029

G

carbamoyl-phosphate synthase 1

mRNA:decreased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:15650968 PMID:17539997

NCBI chr2B:97,735,486...97,936,623
Ensembl chr2B:216,136,857...216,337,728

G

cAMP responsive element binding protein 1

associated with Chemical and Drug Induced Liver Injury

NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130

G

carnitine O-octanoyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:79,339,498...79,393,676
Ensembl chr 7:92,989,868...93,043,832

G

C-reactive protein

protein:decreased expression:serum:

NCBI chr 1:135,062,102...135,064,402

G

cartilage associated protein

CTD Direct Evidence: marker/mechanism

NCBI chr 3:33,040,030...33,071,095
Ensembl chr 3:33,342,694...33,370,863

G

cryptochrome circadian regulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:104,558,874...104,658,833
Ensembl chr12:107,954,262...108,052,484

G

crystallin alpha B

CTD Direct Evidence: marker/mechanism

NCBI chr11:106,795,406...106,800,019
Ensembl chr11:110,639,442...110,644,272

G

cysteine sulfinic acid decarboxylase

CTD Direct Evidence: marker/mechanism

NCBI chr12:35,572,064...35,598,077
Ensembl chr12:36,354,437...36,379,738

G

colony stimulating factor 1 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415

G

colony stimulating factor 3

CTD Direct Evidence: therapeutic

NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729

G

chondroitin sulfate N-acetylgalactosaminyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:18,626,998...18,980,416
Ensembl chr 8:15,576,416...15,904,123

G

cathepsin E

CTD Direct Evidence: marker/mechanism

NCBI chr 1:181,617,421...181,632,260
Ensembl chr 1:185,900,746...185,915,519

G

cathepsin S

CTD Direct Evidence: marker/mechanism

NCBI chr 1:126,084,249...126,118,221
Ensembl chr 1:129,733,996...129,768,318

G

cathepsin Z

CTD Direct Evidence: marker/mechanism

NCBI chr20:55,346,241...55,358,354
Ensembl chr20:56,706,511...56,718,941

G

CTTNBP2 N-terminal like

CTD Direct Evidence: marker/mechanism

NCBI chr 1:115,049,389...115,114,146
Ensembl chr 1:125,236,986...125,300,860

G

CXADR Ig-like cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chr21:4,246,779...4,367,369
Ensembl chr21:17,636,952...17,693,324

G

C-X-C motif chemokine ligand 10

CTD Direct Evidence: marker/mechanism

NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606

G

C-X-C motif chemokine ligand 12

CTD Direct Evidence: marker/mechanism

NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231

G

C-X-C motif chemokine ligand 13

CTD Direct Evidence: marker/mechanism

NCBI chr 4:46,583,759...46,589,865
Ensembl chr 4:52,428,702...52,434,803

G

C-X-C motif chemokine ligand 16

CTD Direct Evidence: marker/mechanism

NCBI chr17:4,789,280...4,795,656
Ensembl chr17:4,778,717...4,785,639

G

C-X-C motif chemokine ligand 9

CTD Direct Evidence: marker/mechanism

NCBI chr 4:48,198,478...48,204,658
Ensembl chr 4:54,036,342...54,042,502

G

cytoglobin

CTD Direct Evidence: therapeutic

NCBI chr17:70,475,651...70,485,987
Ensembl chr17:76,167,947...76,179,412

G

cytochrome P450 family 17 subfamily A member 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:99,431,762...99,439,619
Ensembl chr10:102,896,376...102,901,514

G

cytochrome P450 family 1 subfamily A member 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:53,692,877...53,699,279
Ensembl chr15:73,311,720...73,319,447

G

cytochrome P450 family 26 subfamily A member 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:89,817,623...89,822,024
Ensembl chr10:93,330,460...93,334,105

G

cytochrome P450 family 3 subfamily A member 5

CTD Direct Evidence: marker/mechanism

NCBI chr 7:91,621,561...91,654,164
Ensembl chr 7:105,123,437...105,155,322

G

cytochrome P450 family 7 subfamily A member 1

treatment

NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037

G

CYFIP related Rac1 interactor A

CTD Direct Evidence: marker/mechanism

NCBI chr2A:16,532,230...16,642,397
Ensembl chr2A:16,660,469...16,728,797

G

CYFIP related Rac1 interactor B

CTD Direct Evidence: marker/mechanism

NCBI chr 8:126,478,020...126,653,936
Ensembl chr 8:129,209,655...129,272,844

G

cysteine rich transmembrane module containing 1

CTD Direct Evidence: marker/mechanism

G

dystroglycan 1

mRNA:increased expression:liver

NCBI chr 3:49,396,180...49,464,689
Ensembl chr 3:50,640,615...50,703,852

G

D-amino acid oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr12:106,453,807...106,475,409
Ensembl chr12:109,849,995...109,870,065

G

dopamine beta-hydroxylase

mRNA:decreased expression:superior mesenteric artery (rat)

NCBI chr 9:104,761,504...104,784,445
Ensembl chr 9:133,371,821...133,393,697

G

dysbindin domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:41,738,913...41,743,520
Ensembl chr20:42,829,178...42,833,333

G

dicarbonyl and L-xylulose reductase

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,439,645...76,442,282
Ensembl chr17:82,145,224...82,147,257

G

dopa decarboxylase

CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:superior mesenteric artery (rat)

PMID:18457899 PMID:25380136

NCBI chr 7:51,101,169...51,206,031
Ensembl chr 7:51,345,228...51,449,710

G

DEP domain containing 7

CTD Direct Evidence: marker/mechanism

NCBI chr11:32,992,593...33,010,342
Ensembl chr11:32,877,807...32,895,493

G

dehydrogenase/reductase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:11,319,109...11,370,463
Ensembl chr 1:12,533,696...12,584,381

G

dehydrogenase/reductase 7

CTD Direct Evidence: marker/mechanism

NCBI chr14:40,750,407...40,771,106
Ensembl chr14:59,014,182...59,034,877

G

dehydrogenase E1 and transketolase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:12,073,324...12,130,589
Ensembl chr10:12,054,060...12,108,387

G

iodothyronine deiodinase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 1:53,167,840...53,184,961
Ensembl chr 1:54,762,744...54,779,679

G

divergent protein kinase domain 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 3:140,999,699...141,019,908
Ensembl chr 3:148,590,378...148,607,520

G

dedicator of cytokinesis 10

CTD Direct Evidence: marker/mechanism

NCBI chr2B:112,006,479...112,283,939
Ensembl chr2B:230,578,452...230,854,877

G

dedicator of cytokinesis 7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:61,713,217...61,946,371
Ensembl chr 1:63,529,227...63,740,970

G

dipeptidyl peptidase 7

CTD Direct Evidence: marker/mechanism

NCBI chr 9:108,170,361...108,189,498

G

dihydropyrimidinase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:101,008,090...101,096,234
Ensembl chr 8:103,160,922...103,248,303

G

DNA damage regulated autophagy modulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:99,464,540...99,509,793
Ensembl chr12:102,862,707...102,907,385

G

dihydrouridine synthase 1 like

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,462,543...76,470,556
Ensembl chr17:82,167,347...82,175,253

G

dual specificity phosphatase 16

CTD Direct Evidence: marker/mechanism

NCBI chr12:12,497,185...12,585,591
Ensembl chr12:12,865,400...12,912,502

G

dual specificity phosphatase 6

CTD Direct Evidence: marker/mechanism

NCBI chr12:86,875,289...86,879,731
Ensembl chr12:90,195,482...90,200,321

G

dysferlin

CTD Direct Evidence: marker/mechanism

NCBI chr2A:71,495,573...71,730,073
Ensembl chr2A:72,994,888...73,228,846

G

endothelin converting enzyme 1

protein:increased expression:liver

NCBI chr 1:20,166,019...20,290,803
Ensembl chr 1:21,206,199...21,278,909

G

epithelial cell transforming 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:169,756,885...169,828,087
Ensembl chr 3:177,938,164...178,008,381

G

endothelin 1

CTD Direct Evidence: therapeutic

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

G

EEIG family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:110,938,792...111,014,993
Ensembl chr 1:110,106,643...110,187,680

G

epidermal growth factor

CTD Direct Evidence: marker/mechanism

NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460

G

eukaryotic translation initiation factor 4E family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:71,617,040...71,694,523

G

ELOVL fatty acid elongase 5

CTD Direct Evidence: marker/mechanism

NCBI chr 6:52,822,038...52,902,122
Ensembl chr 6:54,451,887...54,485,878

G

embigin

CTD Direct Evidence: marker/mechanism

NCBI chr 5:63,590,589...63,635,167
Ensembl chr 5:65,204,168...65,247,182

G

epithelial membrane protein 1

CTD Direct Evidence: marker/mechanism

G

ectodermal-neural cortex 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:40,668,899...40,682,887
Ensembl chr 5:41,281,115...41,282,884

G

glutamyl aminopeptidase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:102,969,397...103,056,978
Ensembl chr 4:113,532,126...113,620,654

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

treatment

CTD Direct Evidence: marker/mechanism
protein:increased activity:serum:

PMID:17072980 PMID:17850827 PMID:20957682

RGD:9685426 RGD:9685427

NCBI chr 8:116,248,587...116,364,966
Ensembl chr 8:118,998,530...119,114,273

G

ectonucleoside triphosphate diphosphohydrolase 2

NCBI chr 9:108,108,780...108,114,806
Ensembl chr 9:137,077,207...137,083,031

G

erythrocyte membrane protein band 4.1 like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:128,640,840...128,865,043
Ensembl chr 6:132,747,326...132,878,021

G

epithelial cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chr2A:47,490,748...47,508,418
Ensembl chr2A:48,413,520...48,432,038

G

endoplasmic reticulum aminopeptidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:92,061,414...92,119,087
Ensembl chr 5:97,641,353...97,668,365

G

endoplasmic reticulum to nucleus signaling 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825

G

exostosin like glycosyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:25,280,371...25,295,083
Ensembl chr 1:26,346,391...26,361,118

G

ezrin

CTD Direct Evidence: marker/mechanism

NCBI chr 6:156,656,146...156,709,986
Ensembl chr 6:161,670,483...161,723,102

G

coagulation factor II thrombin receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,110,170...39,129,688
Ensembl chr 5:39,110,170...39,129,688

G

coagulation factor V

treatment

NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915

G

fatty acid binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:111,505,269...111,510,197
Ensembl chr 4:122,055,544...122,060,461

G

fatty acid binding protein 7

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 6:120,539,905...120,574,778
Ensembl chr 6:124,663,054...124,697,905

G

family with sequence similarity 167 member B

CTD Direct Evidence: marker/mechanism

Ensembl chr 1:32,541,067...32,543,226

G

family with sequence similarity 43 member A

CTD Direct Evidence: marker/mechanism

NCBI chr 3:191,981,521...191,984,684
Ensembl chr 3:202,292,603...202,293,877

G

family with sequence similarity 89 member A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:206,569,308...206,590,599

G

Fas cell surface death receptor

mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:17105443 PMID:30737368

NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612

G

FAT atypical cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:178,752,261...178,895,038
Ensembl chr 4:190,952,737...191,093,357

G

fibrillin 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111

G

F-box protein 9

CTD Direct Evidence: marker/mechanism

NCBI chr 6:52,621,036...52,652,980
Ensembl chr 6:54,259,044...54,291,207

G

Fc epsilon receptor Ig

CTD Direct Evidence: marker/mechanism

NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810

G

Fc gamma receptor Ia

CTD Direct Evidence: marker/mechanism

NCBI chr 1:125,127,073...125,136,911
Ensembl chr 1:128,805,484...128,814,220

G

Fc gamma receptor IIIa

CTD Direct Evidence: marker/mechanism

NCBI chr 1:137,027,943...137,036,738

G

fibroblast growth factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942

G

fibroblast growth factor receptor 1

treatment

NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904

G

fibrinogen gamma chain

mRNA:increased expression

NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237

G

fibrinogen like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:69,114,082...69,120,575
Ensembl chr 7:82,926,266...82,932,550

G

FGR proto-oncogene, Src family tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:26,872,781...26,895,751
Ensembl chr 1:27,918,758...27,941,678

G

four and a half LIM domains 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:125,270,340...125,334,961
Ensembl chr X:135,559,321...135,602,375

G

four and a half LIM domains 2

CTD Direct Evidence: marker/mechanism

NCBI chr2A:96,391,513...96,469,267
Ensembl chr2A:106,446,368...106,484,895

G

FKBP prolyl isomerase 1A

CTD Direct Evidence: marker/mechanism

NCBI chr20:1,519,330...1,548,473

G

Fli-1 proto-oncogene, ETS transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr11:123,506,859...123,626,024
Ensembl chr11:127,409,301...127,530,312

G

filamin A

CTD Direct Evidence: marker/mechanism

NCBI chr X:143,799,088...143,825,282

G

formin like 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:12,080,723...12,106,157
Ensembl chr17:12,253,234...12,269,446

G

formin like 2

CTD Direct Evidence: marker/mechanism

NCBI chr2B:39,635,721...39,949,803
Ensembl chr2B:156,874,912...157,188,035

G

flavin containing dimethylaniline monoxygenase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 1:146,742,505...146,778,560
Ensembl chr 1:150,456,729...150,492,527

G

fibronectin 1

treatment

mRNA:increased expression:liver:
mRNA:altered expression:liver (rat)

PMID:15980055 PMID:19914391

RGD:1625201 RGD:4140452

NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003

G

folate receptor beta

CTD Direct Evidence: marker/mechanism

NCBI chr11:67,295,305...67,300,463
Ensembl chr11:70,518,931...70,524,088

G

Fos proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766

G

forkhead box A2

CTD Direct Evidence: marker/mechanism

NCBI chr20:22,519,942...22,524,262

G

forkhead box O1

associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)

NCBI chr13:21,763,729...21,874,279

G

FRY microtubule binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr13:13,104,961...13,555,862
Ensembl chr13:31,541,109...31,990,801

G

follistatin like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:117,508,772...117,564,254
Ensembl chr 3:124,422,968...124,475,431

G

formimidoyltransferase cyclodeaminase

CTD Direct Evidence: marker/mechanism

NCBI chr21:32,481,042...32,501,932
Ensembl chr21:45,734,825...45,753,400

G

FXYD domain containing ion transport regulator 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:112,654,774...112,666,630
Ensembl chr11:116,587,226...116,595,197

G

FXYD domain containing ion transport regulator 5

CTD Direct Evidence: marker/mechanism

NCBI chr19:32,100,475...32,115,826
Ensembl chr19:40,839,798...40,854,027

G

FXYD domain containing ion transport regulator 6

CTD Direct Evidence: marker/mechanism

NCBI chr11:112,671,570...112,712,085
Ensembl chr11:116,606,903...116,609,890

G

FYN proto-oncogene, Src family tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451

G

frizzled class receptor 8

CTD Direct Evidence: marker/mechanism

NCBI chr10:35,766,112...35,770,154

G

G0/G1 switch 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:185,251,903...185,252,882
Ensembl chr 1:190,057,382...190,057,693

G

glucose-6-phosphatase catalytic subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:14,407,355...14,419,660
Ensembl chr17:14,635,667...14,646,674

G

GRB2 associated binding protein 1

protein:increased tyrosine phosphorylation: :

NCBI chr 4:135,697,939...135,834,755
Ensembl chr 4:146,996,936...147,133,672

G

galactosylceramidase

CTD Direct Evidence: marker/mechanism

NCBI chr14:68,545,070...68,605,730
Ensembl chr14:87,905,098...87,965,770

G

golgi associated kinase 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 4:150,443,110...150,492,282
Ensembl chr 4:162,246,728...162,304,069

G

guanylate binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:91,816,602...91,836,594
Ensembl chr 1:90,569,151...90,588,158

G

guanylate binding protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:91,892,368...91,910,048
Ensembl chr 1:90,590,242...90,660,565

G

GC vitamin D binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr 4:52,431,196...52,473,762
Ensembl chr 4:58,729,236...58,792,073

G

glycine C-acetyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr22:18,722,886...18,731,963
Ensembl chr22:36,554,067...36,563,429

G

GTP cyclohydrolase I feedback regulator

CTD Direct Evidence: marker/mechanism

NCBI chr15:19,704,891...19,708,686
Ensembl chr15:37,957,109...37,960,973

G

glucokinase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751

G

glucosaminyl (N-acetyl) transferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:48,333,104...48,400,128
Ensembl chr 9:75,363,369...75,364,655

G

guided entry of tail-anchored proteins factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr21:25,734,722...25,752,196
Ensembl chr21:39,072,103...39,088,928

G

glial fibrillary acidic protein

associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)

NCBI chr17:12,407,211...12,417,072
Ensembl chr17:12,579,754...12,591,961

G

GDNF family receptor alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:112,645,574...112,862,413
Ensembl chr10:116,079,063...116,295,164

G

gamma-glutamyl hydrolase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:59,547,821...59,571,523
Ensembl chr 8:61,222,194...61,246,252

G

glycoprotein alpha-galactosyltransferase 1 (inactive)

CTD Direct Evidence: marker/mechanism

NCBI chr 9:92,572,948...92,631,563

G

growth hormone receptor

mRNA, protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:12679928 PMID:17072980 PMID:25380136

NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278

G

gap junction protein alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:119,213,513...119,227,617

G

gap junction protein alpha 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:34,059,901...34,063,181

G

glycerol kinase

CTD Direct Evidence: marker/mechanism

NCBI chr X:23,250,290...23,327,373
Ensembl chr X:30,806,950...30,877,131

G

GLI pathogenesis related 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:73,006,877...73,028,515
Ensembl chr12:75,858,693...75,879,705

G

glutaminase

CTD Direct Evidence: marker/mechanism

NCBI chr2B:78,182,117...78,267,071
Ensembl chr2B:196,098,910...196,183,323

G

glutaminase 2

CTD Direct Evidence: marker/mechanism

NCBI chr12:32,426,264...32,443,690
Ensembl chr12:32,678,814...32,696,694

G

glycosyltransferase 8 domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:52,634,996...52,646,702
Ensembl chr 3:53,862,812...53,873,900

G

glia maturation factor gamma

CTD Direct Evidence: marker/mechanism

NCBI chr19:36,426,652...36,440,031
Ensembl chr19:44,974,435...44,982,209

G

G protein subunit alpha 14

CTD Direct Evidence: marker/mechanism

NCBI chr 9:47,196,338...47,423,388

G

G protein subunit alpha i2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988

G

G protein subunit gamma transducin 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:8,382,933...8,398,544
Ensembl chr17:8,377,023...8,384,059

G

glucosamine-6-phosphate deaminase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:137,362,575...137,375,079
Ensembl chr 5:143,464,056...143,484,857

G

glutamic-oxaloacetic transaminase 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178

G

glycerol-3-phosphate acyltransferase, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chr10:108,747,370...108,781,270
Ensembl chr10:112,186,744...112,246,549

G

glycoprotein nmb

CTD Direct Evidence: marker/mechanism

NCBI chr 7:23,931,220...23,959,687
Ensembl chr 7:23,539,928...23,568,624

G

G protein-coupled receptor 68

CTD Direct Evidence: marker/mechanism

NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806

G

glutamic--pyruvic transaminase

treatment

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:22706148

Ensembl chr 8:144,259,991...144,263,737

G

glutathione peroxidase 8 (putative)

CTD Direct Evidence: marker/mechanism

NCBI chr 5:58,862,408...58,869,573
Ensembl chr 5:60,484,846...60,492,005

G

G protein-coupled receptor kinase 2

protein:increased expression:aorta

NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066

G

granulin precursor

CTD Direct Evidence: marker/mechanism

NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609

G

gelsolin

CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression

PMID:14574581 PMID:25380136

NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831

G

glutathione S-transferase alpha 4

treatment

NCBI chr 6:52,532,942...52,550,404
Ensembl chr 6:54,171,318...54,188,976

G

glutathione S-transferase mu 1

CTD Direct Evidence: marker/mechanism

Ensembl chr 1:127,979,238...128,010,411

G

GULP PTB domain containing engulfment adaptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr2B:75,588,843...75,896,253
Ensembl chr2B:193,695,139...193,815,861

G

granzyme A

CTD Direct Evidence: marker/mechanism

NCBI chr 5:58,919,129...58,926,620
Ensembl chr 5:60,540,988...60,548,506

G

histidine ammonia-lyase

CTD Direct Evidence: marker/mechanism

NCBI chr12:93,561,401...93,585,215
Ensembl chr12:96,950,020...96,973,662

G

hydroxyacid oxidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,856,967...7,914,818
Ensembl chr20:7,633,861...7,695,120

G

hydroxyacid oxidase 2

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 1:83,160,326...83,185,688
Ensembl chr 1:118,157,037...118,182,957

G

HCK proto-oncogene, Src family tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr20:28,346,244...28,395,370
Ensembl chr20:29,474,737...29,523,399

G

helicase, lymphoid specific

CTD Direct Evidence: marker/mechanism

NCBI chr10:91,282,330...91,344,156
Ensembl chr10:94,790,292...94,847,209

G

HEXIM P-TEFb complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:12,175,544...12,180,077
Ensembl chr17:12,353,590...12,354,669

G

hepatocyte growth factor

CTD Direct Evidence: therapeutic

PMID:10677585 PMID:12918455 PMID:15793283 PMID:16465399 PMID:16627068 More...

NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811

G

huntingtin interacting protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:68,281,899...68,464,233

G

hemojuvelin BMP co-receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 1:121,738,465...121,742,743
Ensembl chr 1:113,926,383...113,930,761

G

3-hydroxy-3-methylglutaryl-CoA reductase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785

G

heme oxygenase 1

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:16025519 PMID:16610050 PMID:19554654 PMID:21163135 PMID:25380136

NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063

G

HOP homeobox

CTD Direct Evidence: marker/mechanism

NCBI chr 4:67,240,801...67,274,419
Ensembl chr 4:73,833,886...73,843,060

G

homeobox A3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:27,750,642...27,767,125
Ensembl chr 7:27,350,491...27,371,169

G

hippocalcin like 1

CTD Direct Evidence: marker/mechanism

NCBI chr2A:10,302,039...10,430,259
Ensembl chr2A:10,578,027...10,585,873

G

hematopoietic prostaglandin D synthase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:86,659,551...86,702,995
Ensembl chr 4:97,332,231...97,375,815

G

heparanase

CTD Direct Evidence: marker/mechanism

PMID:15095483 PMID:18458672

NCBI chr 4:40,863,491...40,905,693
Ensembl chr 4:46,709,621...46,755,157

G

hydroxysteroid 17-beta dehydrogenase 2

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr16:62,642,316...62,705,261
Ensembl chr16:82,062,042...82,125,139

G

hydroxysteroid 17-beta dehydrogenase 6

CTD Direct Evidence: marker/mechanism

NCBI chr12:32,117,696...32,155,740
Ensembl chr12:32,371,489...32,408,860

G

5-hydroxytryptamine receptor 2B

protein:increased expression:liver (rat)

NCBI chr2B:118,362,719...118,381,253
Ensembl chr2B:237,153,709...237,170,591

G

hydroxylysine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr15:57,435,833...57,465,557
Ensembl chr15:76,400,131...76,428,844

G

intercellular adhesion molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:58,095,937...58,114,654
Ensembl chr17:63,189,914...63,207,844

G

inhibitor of DNA binding 2

CTD Direct Evidence: therapeutic

NCBI chr2A:8,681,592...8,684,014
Ensembl chr2A:8,847,776...8,850,720

G

inhibitor of DNA binding 4

CTD Direct Evidence: marker/mechanism

NCBI chr 6:19,665,197...19,668,517

G

indoleamine 2,3-dioxygenase 1

severity

protein:increased expression:serum (mouse)

NCBI chr 8:39,108,310...39,123,611
Ensembl chr 8:36,617,312...36,632,352

G

alpha-L-iduronidase

protein:increased expression:liver

NCBI chr 4:1,102,288...1,120,973
Ensembl chr 4:1,020,582...1,037,877

G

interferon gamma inducible protein 16

CTD Direct Evidence: marker/mechanism

NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424

G

interferon induced protein 35

CTD Direct Evidence: marker/mechanism

NCBI chr17:14,310,106...14,317,648
Ensembl chr17:14,539,625...14,544,931

G

interferon induced transmembrane protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:309,930...311,177
Ensembl chr11:353,236...354,986

G

interferon gamma

CTD Direct Evidence: therapeutic
protein:increased expression:serum (mouse)

PMID:12389079 PMID:15996030 PMID:16953842 PMID:17347453 PMID:28465467

NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829

G

interferon gamma receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:134,958,270...134,980,560
Ensembl chr 6:139,045,821...139,068,053

G

interferon related developmental regulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:104,412,763...104,438,490
Ensembl chr 7:117,115,187...117,141,887

G

insulin like growth factor 1

treatment

CTD Direct Evidence: therapeutic
protein:increased expression:liver:

PMID:12800242 PMID:15591519 PMID:15745444 PMID:16434425 PMID:20198635

RGD:10045984 RGD:12904923 RGD:2317647

NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177

G

insulin like growth factor 1 receptor

protein:increased expression:liver:

NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974

G

insulin like growth factor 2 mRNA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:23,994,839...24,148,709
Ensembl chr 7:23,602,905...23,755,473

G

insulin like growth factor 2 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 6:157,852,565...157,990,049
Ensembl chr 6:162,878,661...162,997,762

G

insulin like growth factor binding protein acid labile subunit

CTD Direct Evidence: marker/mechanism

NCBI chr16:412,671...418,351
Ensembl chr16:1,843,979...1,848,442

G

insulin like growth factor binding protein 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 7:46,538,566...46,545,536
Ensembl chr 7:46,658,097...46,662,584

G

insulin like growth factor binding protein 2

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr2B:103,893,724...103,925,318

G

insulin like growth factor binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:46,564,234...46,573,145

G

insulin like growth factor binding protein 7

treatment

CTD Direct Evidence: marker/mechanism

PMID:25380136 PMID:25691930

NCBI chr 4:66,808,845...66,888,301
Ensembl chr 4:73,382,745...73,462,087

G

immunoglobulin superfamily member 6

CTD Direct Evidence: marker/mechanism

NCBI chr16:15,668,232...15,680,218
Ensembl chr16:87,989,104...88,000,632

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

CTD Direct Evidence: marker/mechanism

NCBI chr X:143,988,720...144,010,078
Ensembl chr X:153,854,493...153,876,092

G

interleukin 10

treatment

CTD Direct Evidence: therapeutic

PMID:12632514 PMID:15362042 PMID:16097045 PMID:16126171 PMID:16539848 More...

RGD:11049490 RGD:7364982

NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371

G

interleukin 17A

treatment

protein:increased expression:liver, serum (mouse)

PMID:28465467 PMID:30346985

RGD:151665755 RGD:39939037

NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074

G

interleukin 17 receptor A

treatment

NCBI chr22:511,091...541,504
Ensembl chr22:15,950,463...15,974,865

G

interleukin 17 receptor C

treatment

NCBI chr 3:9,861,423...9,878,154
Ensembl chr 3:10,210,241...10,226,796

G

interleukin 18

CTD Direct Evidence: marker/mechanism

NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371

G

interleukin 18 binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr11:67,078,251...67,083,043
Ensembl chr11:70,302,923...70,307,511

G

interleukin 1 beta

treatment

CTD Direct Evidence: marker/mechanism

PMID:16085334 PMID:24383550

NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424

G

interleukin 2

treatment

NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984

G

interleukin 2 receptor subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr22:18,039,469...18,069,952
Ensembl chr22:35,874,898...35,899,038

G

interleukin 2 receptor subunit gamma

CTD Direct Evidence: marker/mechanism

NCBI chr X:60,375,815...60,386,936
Ensembl chr X:70,433,360...70,437,590

G

interleukin 33

CTD Direct Evidence: marker/mechanism

NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624

G

interleukin 4

protein:decreased expression:serum (mouse)

NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581

G

interleukin 6

treatment

mRNA:increased expression:liver (mouse)

PMID:24383550 PMID:28465467 PMID:30346985

RGD:10450610 RGD:151665755 RGD:39939037

NCBI chr 7:23,415,922...23,420,767

G

interleukin 7 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 5:74,489,188...74,516,330
Ensembl chr 5:79,769,859...79,792,612

G

integrin linked kinase

CTD Direct Evidence: marker/mechanism

NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788

G

inhibin subunit beta C

CTD Direct Evidence: marker/mechanism

NCBI chr12:31,473,809...31,494,746
Ensembl chr12:31,732,208...31,747,391

G

inhibin subunit beta E

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr12:31,467,974...31,470,700
Ensembl chr12:31,724,252...31,726,978

G

indolethylamine N-methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:31,359,126...31,369,757
Ensembl chr 7:31,485,671...31,489,661

G

inositol polyphosphate-5-phosphatase D

CTD Direct Evidence: marker/mechanism

NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190

G

inositol polyphosphate phosphatase like 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:67,302,066...67,317,785
Ensembl chr11:70,527,017...70,540,846

G

insulin

CTD Direct Evidence: therapeutic

NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666

G

insulin induced gene 2

CTD Direct Evidence: marker/mechanism

NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647

G

IQ motif containing GTPase activating protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:69,076,025...69,190,082
Ensembl chr15:88,276,851...88,388,594

G

interferon regulatory factor 8

CTD Direct Evidence: marker/mechanism

NCBI chr16:66,568,370...66,591,949
Ensembl chr16:85,905,334...85,929,073

G

interferon stimulated exonuclease gene 20

CTD Direct Evidence: marker/mechanism

NCBI chr15:67,328,334...67,345,085
Ensembl chr15:86,536,647...86,553,751

G

inositol-3-phosphate synthase 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:17,913,400...17,916,789
Ensembl chr19:18,884,412...18,887,931

G

integrin subunit alpha 2b

CTD Direct Evidence: marker/mechanism

NCBI chr17:13,009,514...13,027,289
Ensembl chr17:13,176,843...13,193,269

G

integrin subunit alpha L

CTD Direct Evidence: marker/mechanism

NCBI chr16:24,445,966...24,496,037
Ensembl chr16:30,843,747...30,892,597

G

integrin subunit beta 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031

G

integrin subunit beta 2

CTD Direct Evidence: marker/mechanism

NCBI chr21:31,181,228...31,216,033
Ensembl chr21:44,470,999...44,505,963

G

integrin subunit beta 3

CTD Direct Evidence: marker/mechanism

NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382

G

integrin subunit beta 6

mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:18221819 PMID:18538673

NCBI chr2B:47,386,913...47,496,491
Ensembl chr2B:164,764,251...164,867,426

G

isovaleryl-CoA dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr15:19,342,283...19,372,465
Ensembl chr15:37,596,688...37,609,902

G

iodotyrosine deiodinase

CTD Direct Evidence: marker/mechanism

NCBI chr 6:148,178,638...148,216,122
Ensembl chr 6:152,886,373...152,922,152

G

Janus kinase 2

protein:increased expression, increased tyrosine phosphorylation:liver
CTD Direct Evidence: marker/mechanism

PMID:24619965 PMID:25380136

NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626

G

Jun dimerization protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:55,982,051...56,024,816
Ensembl chr14:74,828,944...74,870,087

G

KN motif and ankyrin repeat domains 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:550,713...556,230

G

potassium inwardly rectifying channel subfamily J member 8

CTD Direct Evidence: marker/mechanism

NCBI chr12:64,522,172...64,532,848
Ensembl chr12:67,127,263...67,137,128

G

potassium calcium-activated channel subfamily N member 4

exacerbates

mRNA:increased expression:liver (rat)

NCBI chr19:40,715,621...40,735,025
Ensembl chr19:49,321,403...49,335,900

G

KLF transcription factor 6

CTD Direct Evidence: marker/mechanism

NCBI chr10:3,781,797...3,790,539
Ensembl chr10:3,789,893...3,796,379

G

kynurenine 3-monooxygenase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:217,094,037...217,157,827
Ensembl chr 1:222,075,268...222,138,866

G

kininogen 1

CTD Direct Evidence: therapeutic

NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149

G

keratin 18

CTD Direct Evidence: marker/mechanism
protein:increased expression:liver, plasma membrane (rat)

PMID:15999547 PMID:17072980 PMID:18395095 PMID:21138630 PMID:25380136

NCBI chr12:35,807,660...35,811,691
Ensembl chr12:36,587,149...36,591,196

G

keratin 19

CTD Direct Evidence: marker/mechanism

NCBI chr17:15,788,355...15,793,127
Ensembl chr17:16,006,608...16,010,782

G

keratin 8

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr12:35,855,367...35,863,248
Ensembl chr12:36,634,582...36,642,564

G

kinectin 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:36,162,612...36,266,941
Ensembl chr14:54,467,238...54,539,472

G

kynureninase

CTD Direct Evidence: marker/mechanism

NCBI chr2B:16,792,401...16,947,766
Ensembl chr2B:146,975,995...147,132,634

G

trans-L-3-hydroxyproline dehydratase

CTD Direct Evidence: marker/mechanism

NCBI chr14:40,075,082...40,107,853
Ensembl chr14:58,339,950...58,351,852

G

lysosomal protein transmembrane 5

CTD Direct Evidence: marker/mechanism

NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385

G

LBH regulator of WNT signaling pathway

CTD Direct Evidence: marker/mechanism

NCBI chr2A:30,244,474...30,273,048
Ensembl chr2A:30,320,249...30,411,779

G

lipopolysaccharide binding protein

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr20:34,670,128...34,703,046
Ensembl chr20:35,780,768...35,813,188

G

lipocalin 2

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798

G

lymphocyte cytosolic protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:26,820,846...26,906,916

G

lymphocyte cytosolic protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:165,605,590...165,655,378
Ensembl chr 5:172,365,794...172,414,585

G

lactate dehydrogenase B

CTD Direct Evidence: marker/mechanism

NCBI chr12:64,640,994...64,663,418
Ensembl chr12:67,245,130...67,267,487

G

left-right determination factor 2

ameliorates

NCBI chr 1:201,398,235...201,402,906
Ensembl chr 1:206,397,118...206,401,839

G

leptin

disease_progression

CTD Direct Evidence: marker/mechanism

PMID:12586293 PMID:16097051 PMID:19065677 PMID:20509998 PMID:29248466

RGD:5128589 RGD:5128713

NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519

G

leptin receptor

protein:increased expression:serum

NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768

G

galectin 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:18,593,154...18,597,432
Ensembl chr22:36,426,228...36,430,356

G

galectin 2

CTD Direct Evidence: marker/mechanism

NCBI chr22:18,488,257...18,498,401
Ensembl chr22:36,320,775...36,330,281

G

galectin 3

CTD Direct Evidence: marker/mechanism

PMID:12646584 PMID:16549783 PMID:25380136

RGD:9685223 RGD:9685224

NCBI chr14:35,715,850...35,732,263
Ensembl chr14:53,990,023...54,006,412

G

galectin like

CTD Direct Evidence: marker/mechanism

NCBI chr2A:64,522,883...64,529,902
Ensembl chr2A:65,642,060...65,653,141

G

legumain

CTD Direct Evidence: marker/mechanism

NCBI chr14:73,337,607...73,383,462
Ensembl chr14:92,677,608...92,723,051

G

LHFPL tetraspan subfamily member 6

CTD Direct Evidence: marker/mechanism

NCBI chr13:20,560,260...20,819,037
Ensembl chr13:39,182,518...39,403,746

G

LIM domain kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr22:12,235,611...12,304,013
Ensembl chr22:30,071,574...30,139,821

G

lin-7 homolog A, crumbs cell polarity complex component

CTD Direct Evidence: marker/mechanism

NCBI chr12:78,312,501...78,456,871
Ensembl chr12:81,442,152...81,567,522

G

LIM domain only 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:33,830,370...33,863,960

G

HLA class II histocompatibility antigen, DM alpha chain

CTD Direct Evidence: marker/mechanism

NCBI chr 6:32,518,060...32,537,989
Ensembl chr 6:33,634,123...33,637,988

G

alcohol dehydrogenase 1C

CTD Direct Evidence: marker/mechanism

NCBI chr 4:91,756,817...91,773,056
Ensembl chr 4:102,388,575...102,435,079

G

somatotropin

CTD Direct Evidence: therapeutic

NCBI chr17:58,010,848...58,013,421
Ensembl chr17:63,103,332...63,105,067

G

interferon alpha-2

CTD Direct Evidence: therapeutic

NCBI chr 9:21,245,017...21,246,210
Ensembl chr 9:21,863,062...21,863,736

G

acylpyruvase FAHD1, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chr16:449,359...451,070

G

olfactory receptor 51E2

CTD Direct Evidence: marker/mechanism

NCBI chr11:4,853,325...4,871,457
Ensembl chr11:4,520,050...4,521,012

G

growth-regulated alpha protein

CTD Direct Evidence: marker/mechanism

NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474

G

tropomyosin alpha-3 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 1:129,511,914...129,538,703
Ensembl chr 1:133,126,641...133,161,894

G

alpha-2-macroglobulin

CTD Direct Evidence: marker/mechanism

NCBI chr12:9,154,457...9,202,833
Ensembl chr12:9,385,359...9,433,979

G

adenosine receptor A3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:114,144,642...114,225,407
Ensembl chr 1:126,122,352...126,202,396

G

plasminogen

CTD Direct Evidence: therapeutic

NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777

G

cytochrome b-245 heavy chain

CTD Direct Evidence: marker/mechanism

NCBI chr X:30,230,394...30,267,379
Ensembl chr X:37,939,704...37,973,183

G

signal transducer CD24

CTD Direct Evidence: marker/mechanism

NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847

G

metallothionein-2

CTD Direct Evidence: marker/mechanism

NCBI chr16:36,894,853...36,895,826
Ensembl chr16:56,007,922...56,028,093

G

cytochrome b-245 light chain

CTD Direct Evidence: marker/mechanism

NCBI chr16:69,356,396...69,364,225
Ensembl chr16:89,016,349...89,024,719

G

HLA class II histocompatibility antigen, DR alpha chain

CTD Direct Evidence: marker/mechanism

NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417

G

cytochrome P450 2D6-like

CTD Direct Evidence: marker/mechanism

NCBI chr22:23,022,449...23,031,627

G

signal transducer and activator of transcription 5A

treatment

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

G

mitochondrial adenyl nucleotide antiporter SLC25A24

CTD Direct Evidence: marker/mechanism

NCBI chr 1:110,672,168...110,736,204
Ensembl chr 1:109,786,563...109,850,397

G

hydroxyacylglutathione hydrolase, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chr16:431,417...455,211

G

ficolin-1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:106,039,315...106,047,648
Ensembl chr 9:135,040,310...135,049,111

G

lysyl oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:117,450,833...117,464,957
Ensembl chr 5:123,234,662...123,248,717

G

lysyl oxidase like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:22,547,303...22,653,676
Ensembl chr 8:19,483,335...19,589,522

G

lipoprotein lipase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:19,164,541...19,193,100
Ensembl chr 8:16,113,415...16,142,966

G

leupaxin

CTD Direct Evidence: marker/mechanism

NCBI chr11:53,781,270...53,832,785
Ensembl chr11:57,243,028...57,293,442

G

lecithin retinol acyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:147,110,568...147,119,706
Ensembl chr 4:158,928,607...158,937,747

G

LDL receptor related protein 6

NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973

G

leucine rich repeat containing 28

CTD Direct Evidence: marker/mechanism

NCBI chr15:77,932,476...78,069,106
Ensembl chr15:97,117,104...97,250,570

G

LRR binding FLII interacting protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr2B:124,856,660...125,013,602
Ensembl chr2B:243,775,371...243,863,116

G

leukotriene A4 hydrolase

CTD Direct Evidence: marker/mechanism

NCBI chr12:93,589,758...93,624,529
Ensembl chr12:96,978,203...97,012,427

G

lymphotoxin beta

CTD Direct Evidence: marker/mechanism

NCBI chr 6:31,241,643...31,244,454
Ensembl chr 6:32,131,760...32,133,467

G

latent transforming growth factor beta binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr2A:32,956,937...33,409,286
Ensembl chr2A:33,667,191...34,120,602

G

lumican

CTD Direct Evidence: marker/mechanism

NCBI chr12:88,636,825...88,644,665
Ensembl chr12:91,952,277...91,960,388

G

leucine rich adaptor protein 1 like

CTD Direct Evidence: marker/mechanism

NCBI chr 9:12,613,596...12,662,950
Ensembl chr 9:13,061,445...13,109,923

G

lymphocyte antigen 86

CTD Direct Evidence: marker/mechanism

NCBI chr 6:6,429,846...6,496,664
Ensembl chr 6:6,610,431...6,676,696

G

lymphocyte antigen 96

CTD Direct Evidence: marker/mechanism

NCBI chr 8:70,525,058...70,567,839
Ensembl chr 8:72,169,986...72,207,372

G

MAGE family member E1

CTD Direct Evidence: marker/mechanism

NCBI chr X:65,654,865...65,658,586
Ensembl chr X:75,769,619...75,772,870

G

microtubule associated protein 1 light chain 3 alpha

CTD Direct Evidence: marker/mechanism

NCBI chr20:30,887,345...30,888,986
Ensembl chr20:32,010,284...32,020,411

G

mitogen-activated protein kinase kinase kinase 8

CTD Direct Evidence: marker/mechanism

NCBI chr10:30,579,220...30,607,249
Ensembl chr10:30,933,483...30,960,824

G

mitogen-activated protein kinase 1

treatment

NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335

G

mitogen-activated protein kinase 3

treatment

Ensembl chr16:30,489,362...30,498,017

G

MAS1 proto-oncogene, G protein-coupled receptor

mRNA:increased expression:liver (rat)

NCBI chr 6:157,774,098...157,799,983
Ensembl chr 6:162,801,416...162,802,393

G

malate dehydrogenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr2A:63,658,933...63,677,257
Ensembl chr2A:64,785,132...64,803,631

G

mesenchyme homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:16,268,225...16,343,914
Ensembl chr 7:15,598,466...15,673,935

G

MET proto-oncogene, receptor tyrosine kinase

protein:decreased expression:liver (rat)

NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159

G

meteorin like, glial cell differentiation regulator

CTD Direct Evidence: marker/mechanism

NCBI chr17:77,511,681...77,527,677
Ensembl chr17:83,287,606...83,301,637

G

microfibril associated protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr17:31,725,732...31,729,528
Ensembl chr17:36,890,778...36,893,230

G

mitofusin 2

treatment

mRNA, protein:decreased expression:liver (rat)

PMID:25369251 PMID:26882442

RGD:12910839 RGD:13204798

NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077

G

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr2B:25,394,435...25,724,420
Ensembl chr2B:138,344,539...138,538,857

G

O-6-methylguanine-DNA methyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr10:126,059,701...126,365,850
Ensembl chr10:130,305,485...130,609,422

G

matrix Gla protein

CTD Direct Evidence: marker/mechanism

NCBI chr12:14,887,806...14,891,796
Ensembl chr12:15,284,883...15,288,523

G

HLA class II histocompatibility antigen, DM beta chain

CTD Direct Evidence: marker/mechanism

NCBI chr 6:32,504,074...32,510,669
Ensembl chr 6:33,619,870...33,625,685

G

MID1 interacting protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:31,246,622...31,251,703
Ensembl chr X:38,957,396...38,957,947

G

macrophage migration inhibitory factor

protein:increased expression:hepatocyte

NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009

G

MINDY lysine 48 deubiquitinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:16,101,605...16,183,746
Ensembl chr10:16,377,064...16,459,135

G

MIS12 kinetochore complex component

CTD Direct Evidence: marker/mechanism

NCBI chr17:5,534,305...5,538,736
Ensembl chr17:5,529,017...5,529,634

G

marker of proliferation Ki-67

CTD Direct Evidence: marker/mechanism

NCBI chr10:124,684,336...124,714,143
Ensembl chr10:128,936,037...128,962,555

G

membrane metalloendopeptidase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:152,085,694...152,240,148
Ensembl chr 3:160,197,566...160,292,119

G

matrix metallopeptidase 1

CTD Direct Evidence: therapeutic

NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104

G

matrix metallopeptidase 13

treatment

CTD Direct Evidence: therapeutic

PMID:10623612 PMID:17404313

NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679

G

matrix metallopeptidase 15

CTD Direct Evidence: marker/mechanism

NCBI chr16:38,304,856...38,326,193
Ensembl chr16:57,433,813...57,457,122

G

matrix metallopeptidase 2

CTD Direct Evidence: marker/mechanism

PMID:15095483 PMID:25380136

NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279

G

matrix metallopeptidase 3

NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354

G

matrix metallopeptidase 8

CTD Direct Evidence: therapeutic

NCBI chr11:97,650,408...97,663,731
Ensembl chr11:101,143,268...101,156,736

G

matrix metallopeptidase 9

CTD Direct Evidence: marker/mechanism

NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129

G

MOB kinase activator 3A

CTD Direct Evidence: marker/mechanism

NCBI chr19:1,080,455...1,106,215
Ensembl chr19:2,053,856...2,068,807

G

maestro

CTD Direct Evidence: marker/mechanism

NCBI chr18:44,172,007...44,202,095
Ensembl chr18:47,522,590...47,543,216

G

moesin

CTD Direct Evidence: marker/mechanism

NCBI chr X:54,785,309...54,859,364
Ensembl chr X:64,781,550...64,933,292

G

myotubularin related protein 7

CTD Direct Evidence: marker/mechanism

NCBI chr 8:16,509,712...16,626,018
Ensembl chr 8:13,454,694...13,571,706

G

mechanistic target of rapamycin kinase

treatment

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

G

major vault protein

CTD Direct Evidence: marker/mechanism

Ensembl chr16:30,190,090...30,219,070

G

myeloid associated differentiation marker

CTD Direct Evidence: marker/mechanism

NCBI chr19:50,807,615...50,817,196
Ensembl chr19:59,663,790...59,664,758

G

MYC proto-oncogene, bHLH transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863

G

myosin light chain 9

CTD Direct Evidence: marker/mechanism

NCBI chr20:32,875,033...32,883,444
Ensembl chr20:33,993,482...34,001,850

G

myosin IC

CTD Direct Evidence: marker/mechanism

NCBI chr17:1,446,506...1,475,634
Ensembl chr17:1,345,143...1,375,540

G

myosin IF

CTD Direct Evidence: marker/mechanism

NCBI chr19:7,807,863...7,858,955
Ensembl chr19:8,656,082...8,705,107

G

myosin VA

CTD Direct Evidence: marker/mechanism

NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319

G

myocilin

CTD Direct Evidence: marker/mechanism

NCBI chr 1:147,128,541...147,146,227
Ensembl chr 1:150,841,630...150,858,628

G

N-acetylglucosamine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr2A:71,114,832...71,125,182
Ensembl chr2A:72,616,077...72,626,435

G

nucleosome assembly protein 1 like 5

CTD Direct Evidence: marker/mechanism

NCBI chr 4:80,985,470...80,987,440

G

N-acetyltransferase 8 (putative)

CTD Direct Evidence: marker/mechanism

NCBI chr2A:73,702,173...73,703,763
Ensembl chr2A:75,189,726...75,190,409

G

neurobeachin

CTD Direct Evidence: marker/mechanism

NCBI chr13:16,182,613...16,891,082
Ensembl chr13:34,614,820...35,322,521

G

NCK associated protein 1 like

CTD Direct Evidence: marker/mechanism

NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881

G

nuclear receptor corepressor 2

CTD Direct Evidence: marker/mechanism

NCBI chr12:121,913,368...122,155,031
Ensembl chr12:126,201,779...126,372,745

G

N-myc downstream regulated 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:129,891,918...129,952,489
Ensembl chr 8:132,866,245...132,926,514

G

NDRG family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:1,831,764...1,840,819
Ensembl chr14:19,913,674...19,967,470

G

nectin cell adhesion molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:41,794,037...41,837,047
Ensembl chr19:50,399,668...50,443,024

G

NIMA related kinase 6

CTD Direct Evidence: marker/mechanism

NCBI chr 9:95,379,090...95,474,348
Ensembl chr 9:123,903,240...123,994,658

G

NFE2 like bZIP transcription factor 2

CTD Direct Evidence: therapeutic

NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085

G

NFKB inhibitor alpha

CTD Direct Evidence: marker/mechanism

NCBI chr14:16,155,331...16,158,588

G

NFKB inhibitor epsilon

CTD Direct Evidence: marker/mechanism

NCBI chr 6:43,853,921...43,861,686
Ensembl chr 6:45,138,209...45,144,680

G

NFKB inhibitor zeta

CTD Direct Evidence: marker/mechanism

NCBI chr 3:98,914,957...98,948,467
Ensembl chr 3:105,616,645...105,628,300

G

NHS like 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:32,035,021...32,067,932
Ensembl chr 1:33,198,889...33,231,893

G

nidogen 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:211,543,294...211,631,769
Ensembl chr 1:216,544,829...216,632,935

G

nidogen 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:32,604,392...32,668,121
Ensembl chr14:50,890,317...50,953,830

G

NIPA like domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:94,826,325...94,938,586
Ensembl chr 8:97,013,882...97,118,281

G

NLR family CARD domain containing 5

CTD Direct Evidence: marker/mechanism

NCBI chr16:37,267,541...37,361,369
Ensembl chr16:56,433,204...56,494,027

G

N-myc and STAT interactor

CTD Direct Evidence: marker/mechanism

NCBI chr2B:8,574,385...8,603,486
Ensembl chr2B:155,802,720...155,823,142

G

nocturnin

CTD Direct Evidence: marker/mechanism

NCBI chr 4:131,378,656...131,409,711
Ensembl chr 4:142,691,169...142,719,514

G

nitric oxide synthase 2

mRNA:increased expression:aorta
CTD Direct Evidence: therapeutic
mRNA:increased expression:heart

PMID:10353629 PMID:10784593 PMID:18380797

RGD:2325265 RGD:2325278

NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093

G

nitric oxide synthase 3

protein:decreased expression:spleen
protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:17481668 PMID:17918268 PMID:18555214

RGD:2292126 RGD:2292140

NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233

G

NADPH oxidase 4

CTD Direct Evidence: marker/mechanism

NCBI chr11:84,330,362...84,496,755

G

neuronal PAS domain protein 2

CTD Direct Evidence: marker/mechanism

Ensembl chr2A:101,868,933...101,972,866

G

neural proliferation, differentiation and control 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:108,100,164...108,107,324
Ensembl chr 9:137,068,846...137,072,257

G

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:2,819,422...2,844,765
Ensembl chr 6:2,928,021...2,947,304

G

nuclear receptor subfamily 0 group B member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:26,174,055...26,176,689
Ensembl chr 1:27,230,362...27,232,942

G

nuclear receptor subfamily 1 group H member 4

treatment

mRNA:altered expression:liver (rat)
associated with portal hypertension;mRNA;decreased expression;liver (rat)

PMID:15980055 PMID:24259407 PMID:27993716

RGD:14701034 RGD:15045598 RGD:1625201

NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058

G

neuronal regeneration related protein

CTD Direct Evidence: marker/mechanism

NCBI chr 5:107,089,968...107,118,919

G

neuregulin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977

G

negative regulator of reactive oxygen species

CTD Direct Evidence: marker/mechanism

NCBI chr 3:193,984,797...194,007,173
Ensembl chr 3:203,920,334...203,948,506

G

NMDA receptor synaptonuclear signaling and neuronal migration factor

CTD Direct Evidence: marker/mechanism

NCBI chr 9:108,518,698...108,531,316
Ensembl chr 9:137,482,420...137,495,990

G

5'-nucleotidase ecto

CTD Direct Evidence: marker/mechanism

NCBI chr 6:83,333,428...83,379,585
Ensembl chr 6:86,615,409...86,661,601

G

nudix hydrolase 16

CTD Direct Evidence: marker/mechanism

NCBI chr 3:128,466,119...128,473,186
Ensembl chr 3:135,788,354...135,790,038

G

nuclear protein 1, transcriptional regulator

CTD Direct Evidence: marker/mechanism

Ensembl chr16:29,015,155...29,016,987

G

ornithine aminotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr10:120,955,805...120,977,484
Ensembl chr10:125,224,032...125,245,504

G

8-oxoguanine DNA glycosylase

treatment

NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335

G

olfactomedin like 2B

CTD Direct Evidence: marker/mechanism

NCBI chr 1:137,401,323...137,442,611
Ensembl chr 1:141,200,355...141,241,629

G

olfactomedin like 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:88,575,167...88,577,992
Ensembl chr 1:123,624,824...123,627,681

G

oxidative stress induced growth inhibitor 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:64,555,632...64,590,930
Ensembl chr16:83,942,912...83,978,111

G

oncostatin M

CTD Direct Evidence: therapeutic

NCBI chr22:11,298,965...11,303,009
Ensembl chr22:29,101,085...29,105,081

G

ornithine transcarbamylase

CTD Direct Evidence: marker/mechanism
protein:decreased activity:liver (rat)

PMID:7865721 PMID:25380136

NCBI chr X:30,796,828...30,868,144
Ensembl chr X:38,505,232...38,575,819

G

OTU deubiquitinase, ubiquitin aldehyde binding 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:74,658,535...74,681,084
Ensembl chr14:93,991,913...94,015,157

G

OTU deubiquitinase with linear linkage specificity like

CTD Direct Evidence: marker/mechanism

NCBI chr 5:14,887,866...14,921,996
Ensembl chr 5:14,727,987...14,757,018

G

palmdelphin

CTD Direct Evidence: marker/mechanism

NCBI chr 1:102,301,659...102,354,307
Ensembl chr 1:101,021,477...101,069,862

G

peptidase domain containing associated with muscle regeneration 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:35,404,636...35,498,705
Ensembl chr11:35,279,225...35,373,862

G

progestin and adipoQ receptor family member 9

CTD Direct Evidence: marker/mechanism

NCBI chr 3:139,985,648...139,997,993
Ensembl chr 3:147,588,041...147,589,144

G

pyruvate carboxylase

CTD Direct Evidence: marker/mechanism

NCBI chr11:62,205,644...62,317,917
Ensembl chr11:65,527,662...65,551,396

G

phosphoenolpyruvate carboxykinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920

G

phosphoenolpyruvate carboxykinase 2, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chr14:4,872,276...4,882,118
Ensembl chr14:22,996,813...23,006,775

G

platelet derived growth factor subunit A

CTD Direct Evidence: marker/mechanism

NCBI chr 7:648,722...672,023

G

platelet derived growth factor receptor alpha

treatment

CTD Direct Evidence: marker/mechanism

PMID:17382907 PMID:25380136

NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097

G

platelet derived growth factor receptor beta

treatment

CTD Direct Evidence: marker/mechanism

PMID:15077122 PMID:15623374 PMID:18466260

RGD:10449503 RGD:2292206

NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530

G

pyridoxal kinase

protein:decreased expression:brain

NCBI chr21:29,977,286...30,021,266
Ensembl chr21:43,273,237...43,313,637

G

PDZ domain containing ring finger 3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:73,322,613...73,565,929
Ensembl chr 3:75,246,558...75,488,499

G

proliferation and apoptosis adaptor protein 15

CTD Direct Evidence: marker/mechanism

NCBI chr 1:135,559,273...135,569,392
Ensembl chr 1:139,480,394...139,490,503

G

phosphofructokinase, platelet

CTD Direct Evidence: marker/mechanism

NCBI chr10:3,062,844...3,134,955
Ensembl chr10:3,080,242...3,244,790

G

profilin 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022

G

placental growth factor

disease_progression

PMID:17935226 PMID:21520176

RGD:1643338 RGD:6483607

NCBI chr14:55,494,152...55,508,066
Ensembl chr14:74,338,976...74,352,964

G

polycystin 2, transient receptor potential cation channel

CTD Direct Evidence: marker/mechanism

NCBI chr 4:80,295,243...80,365,271
Ensembl chr 4:91,019,734...91,086,775

G

pyruvate kinase L/R

CTD Direct Evidence: marker/mechanism

NCBI chr 1:130,634,111...130,646,644
Ensembl chr 1:134,239,565...134,251,351

G

phospholipase A2 group XIIA

CTD Direct Evidence: marker/mechanism

NCBI chr 4:102,207,312...102,226,307
Ensembl chr 4:112,773,886...112,794,063

G

phospholipase A2 group IVA

protein:increased activity:liver
CTD Direct Evidence: marker/mechanism

PMID:17459512 PMID:25380136

NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101

G

placenta associated 8

CTD Direct Evidence: marker/mechanism

NCBI chr 4:41,089,847...41,115,061
Ensembl chr 4:46,943,940...46,964,131

G

plasminogen activator, tissue type

CTD Direct Evidence: marker/mechanism

PMID:20035854 PMID:25380136

NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779

G

plasminogen activator, urokinase

treatment

CTD Direct Evidence: marker/mechanism

PMID:16958060 PMID:20035854 PMID:23018346 PMID:25380136

RGD:2317516 RGD:6484134 RGD:7241553

NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136

G

phospholipase D family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr14:85,574,724...85,587,176
Ensembl chr14:105,360,584...105,369,247

G

pleckstrin

CTD Direct Evidence: marker/mechanism

NCBI chr2A:68,414,281...68,446,647
Ensembl chr2A:69,537,983...69,570,393

G

pleckstrin homology domain containing B1

CTD Direct Evidence: marker/mechanism

NCBI chr11:68,724,168...68,739,450
Ensembl chr11:72,035,823...72,052,130

G

pleckstrin homology, MyTH4 and FERM domain containing H1

CTD Direct Evidence: marker/mechanism

NCBI chr14:48,111,017...48,167,541
Ensembl chr14:66,989,471...67,045,677

G

perilipin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:18,928,455...18,951,132
Ensembl chr 9:19,421,928...19,462,222

G

perilipin 3

CTD Direct Evidence: marker/mechanism

NCBI chr19:3,857,506...3,886,274
Ensembl chr19:4,808,512...4,835,180

G

procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:143,091,833...143,181,831
Ensembl chr 3:150,675,424...150,764,939

G

phospholipid phosphatase 2

CTD Direct Evidence: marker/mechanism

Ensembl chr19:238,770...246,004

G

phospholipid scramblase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:143,528,967...143,558,468
Ensembl chr 3:151,112,483...151,132,964

G

phospholipid scramblase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:143,446,683...143,509,767
Ensembl chr 3:151,029,766...151,092,437

G

phospholipid transfer protein

CTD Direct Evidence: marker/mechanism

NCBI chr20:42,237,434...42,251,189
Ensembl chr20:43,324,609...43,337,999

G

prostate transmembrane protein, androgen induced 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347

G

proopiomelanocortin

CTD Direct Evidence: therapeutic

PMID:16508911 PMID:16511523

NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706

G

peroxisome proliferator activated receptor gamma

treatment

PMID:18594976 PMID:22529699

RGD:2301874 RGD:8553190

NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060

G

protein phosphatase 1 regulatory subunit 18

CTD Direct Evidence: marker/mechanism

NCBI chr 6:30,421,134...30,431,964
Ensembl chr 6:31,290,562...31,301,566

G

protein phosphatase 1 regulatory subunit 3B

CTD Direct Evidence: marker/mechanism

NCBI chr 8:10,059,531...10,074,820

G

protein phosphatase 1 regulatory subunit 3C

CTD Direct Evidence: marker/mechanism

NCBI chr10:88,377,396...88,382,205
Ensembl chr10:91,900,112...91,904,764

G

PRA1 domain family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr X:41,369,432...41,372,322
Ensembl chr X:49,224,864...49,233,960

G

protein kinase C beta

CTD Direct Evidence: marker/mechanism

NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203

G

protein kinase C delta

CTD Direct Evidence: marker/mechanism

NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910

G

parkin RBR E3 ubiquitin protein ligase

treatment

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

G

prolactin receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 5:75,139,852...75,321,695
Ensembl chr 5:80,532,058...80,600,403

G

prion protein (Kanno blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr20:4,713,616...4,728,847
Ensembl chr20:4,523,155...4,523,916

G

protein C receptor

CTD Direct Evidence: marker/mechanism

NCBI chr20:31,500,838...31,543,928
Ensembl chr20:32,622,876...32,628,320

G

proline dehydrogenase 1

CTD Direct Evidence: marker/mechanism

NCBI chr22:1,654,019...1,678,389

G

proline dehydrogenase 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:32,713,686...32,726,964
Ensembl chr19:41,462,735...41,476,308

G

protein S

mRNA, protein:decreased expression:liver, plasma

NCBI chr 3:90,934,641...91,039,059
Ensembl chr 3:97,615,734...97,718,756

G

proline rich 13

CTD Direct Evidence: marker/mechanism

NCBI chr12:35,307,016...35,312,012
Ensembl chr12:36,091,140...36,096,219

G

phosphoribosyl transferase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:25,023,015...25,127,770
Ensembl chr10:25,393,227...25,497,054

G

protogenin

CTD Direct Evidence: marker/mechanism

NCBI chr15:34,579,267...34,715,039
Ensembl chr15:52,910,486...53,032,562

G

prune homolog 2 with BCH domain

CTD Direct Evidence: marker/mechanism

NCBI chr 9:47,935,632...48,229,860
Ensembl chr 9:75,474,234...75,764,547

G

proteasome 20S subunit beta 10

CTD Direct Evidence: marker/mechanism

NCBI chr16:48,275,764...48,278,108
Ensembl chr16:67,663,344...67,666,359

G

proteasome 20S subunit beta 8

CTD Direct Evidence: marker/mechanism

NCBI chr 6:32,410,172...32,414,136
Ensembl chr 6:33,525,681...33,529,897

G

proteasome 20S subunit beta 9

CTD Direct Evidence: marker/mechanism

NCBI chr 6:32,423,614...32,429,062
Ensembl chr 6:33,539,060...33,564,402

G

proteasome activator subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:4,919,628...4,922,952
Ensembl chr14:23,043,807...23,047,296

G

proline-serine-threonine phosphatase interacting protein 1

CTD Direct Evidence: marker/mechanism

Ensembl chr15:75,533,114...75,552,365

G

platelet activating factor receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861

G

phosphotriesterase related

CTD Direct Evidence: marker/mechanism

NCBI chr10:16,754,485...16,830,379
Ensembl chr10:17,029,057...17,105,594

G

prostaglandin E receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:32,910,755...32,926,138
Ensembl chr14:51,195,381...51,209,686

G

prostaglandin-endoperoxide synthase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283

G

prostaglandin-endoperoxide synthase 2

CTD Direct Evidence: marker/mechanism

PMID:17565644 PMID:18555214

NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519

G

protein tyrosine kinase 2

mRNA, protein:increased expression:liver

NCBI chr 8:137,330,777...137,677,306
Ensembl chr 8:140,412,773...140,684,898

G

pleiotrophin

CTD Direct Evidence: marker/mechanism

NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623

G

protein tyrosine phosphatase non-receptor type 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421

G

protein tyrosine phosphatase non-receptor type 18

CTD Direct Evidence: marker/mechanism

NCBI chr2B:28,642,193...28,662,242
Ensembl chr2B:131,270,974...131,287,803

G

protein tyrosine phosphatase receptor type C

CTD Direct Evidence: marker/mechanism

NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994

G

protein tyrosine phosphatase receptor type D

CTD Direct Evidence: marker/mechanism

NCBI chr 9:8,113,171...10,420,732
Ensembl chr 9:8,288,569...8,831,227

G

protein tyrosine phosphatase receptor type O

CTD Direct Evidence: marker/mechanism

NCBI chr12:15,329,314...15,594,787
Ensembl chr12:15,725,917...15,990,532

G

peptidyl-tRNA hydrolase 1 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr 9:98,813,010...98,835,732
Ensembl chr 9:127,484,509...127,507,753

G

peptidyl-tRNA hydrolase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr2A:24,783,531...24,786,971
Ensembl chr2A:24,878,810...24,882,328

G

peroxidasin

CTD Direct Evidence: marker/mechanism

NCBI chr2A:1,584,901...1,699,675
Ensembl chr2A:1,582,193...1,692,033

G

PYD and CARD domain containing

CTD Direct Evidence: marker/mechanism

NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828

G

pyrroline-5-carboxylate reductase 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,337,991...76,348,207
Ensembl chr17:82,040,824...82,045,686

G

R3H domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr12:31,494,789...31,672,343
Ensembl chr12:31,868,368...31,923,910

G

RAB30, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr11:78,040,163...78,136,785
Ensembl chr11:81,659,732...81,711,750

G

RAB31, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr18:4,424,677...4,578,263
Ensembl chr18:6,710,174...6,859,896

G

RAB32, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr 6:144,339,323...144,354,885

G

RAB40B, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

Ensembl chr17:82,872,403...82,902,803

G

RAB8B, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr15:42,136,776...42,214,792
Ensembl chr15:60,432,749...60,510,547

G

RAB GTPase activating protein 1 like

CTD Direct Evidence: marker/mechanism

NCBI chr 1:149,676,356...150,506,884
Ensembl chr 1:153,437,265...154,199,810

G

Rac family small GTPase 2

CTD Direct Evidence: marker/mechanism

NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026

G

receptor activity modifying protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr2B:125,092,164...125,144,032
Ensembl chr2B:243,942,771...243,995,221

G

receptor activity modifying protein 2

NCBI chr17:14,554,888...14,557,175
Ensembl chr17:14,779,666...14,781,481

G

retinoic acid receptor responder 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:155,722,334...155,758,228

G

Ras association domain family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr10:41,954,378...41,989,334
Ensembl chr10:45,134,004...45,168,949

G

RB transcriptional corepressor like 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:33,674,751...33,731,308
Ensembl chr16:52,759,290...52,816,175

G

RNA binding motif protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr X:40,872,745...40,876,611
Ensembl chr X:48,734,777...48,738,077

G

retinol binding protein 4

mRNA:increased expression:liver (rat)

NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887

G

reticulocalbin 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:32,054,917...32,069,524

G

reticulocalbin 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:55,857,130...55,875,365
Ensembl chr15:75,445,908...75,463,947

G

RCSD domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:143,062,602...143,138,987
Ensembl chr 1:146,899,485...146,921,977

G

retinol dehydrogenase 10

CTD Direct Evidence: marker/mechanism

NCBI chr 8:69,833,320...69,863,536
Ensembl chr 8:71,481,089...71,510,689

G

retinol dehydrogenase 13

CTD Direct Evidence: marker/mechanism

NCBI chr19:52,081,674...52,107,781
Ensembl chr19:60,776,114...60,794,267

G

reversion inducing cysteine rich protein with kazal motifs

CTD Direct Evidence: marker/mechanism

NCBI chr 9:35,886,741...35,974,133
Ensembl chr 9:36,699,631...36,774,116

G

receptor accessory protein 5

CTD Direct Evidence: marker/mechanism

NCBI chr 5:108,236,654...108,280,724

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism

NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868

G

RELT like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:31,939,962...32,013,856
Ensembl chr 4:37,798,632...37,869,421

G

reelin

mRNA, protein:increased expression:liver, plasma (rat)

NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037

G

regucalcin

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr X:39,513,135...39,530,188
Ensembl chr X:47,371,226...47,388,881

G

regulator of G protein signaling 10

CTD Direct Evidence: marker/mechanism

NCBI chr10:116,070,326...116,113,422
Ensembl chr10:119,492,159...119,534,443

G

regulator of G protein signaling 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:168,273,112...168,276,348
Ensembl chr 1:172,566,701...172,569,955

G

regulator of G protein signaling 3

CTD Direct Evidence: marker/mechanism

NCBI chr 9:84,561,302...84,696,534
Ensembl chr 9:112,927,407...113,065,746

G

regulator of G protein signaling 5

CTD Direct Evidence: marker/mechanism

NCBI chr 1:138,561,940...138,622,698
Ensembl chr 1:142,362,663...142,387,291

G

ras homolog family member A

mRNA, protein:increased expression:liver

PMID:16492715 PMID:17596891

RGD:1642803 RGD:2298879

NCBI chr 3:49,282,009...49,339,887

G

ras homolog family member Q

CTD Direct Evidence: marker/mechanism

NCBI chr2A:46,657,884...46,698,604

G

reactive intermediate imine deaminase A homolog

treatment

NCBI chr 8:94,739,120...94,753,934
Ensembl chr 8:96,923,776...96,938,512

G

Ras like without CAAX 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:131,232,277...131,245,437
Ensembl chr 1:135,063,000...135,074,942

G

regulator of microtubule dynamics 2

CTD Direct Evidence: marker/mechanism

NCBI chr2A:37,948,081...38,087,498
Ensembl chr2A:38,716,147...38,800,755

G

required for meiotic nuclear division 5 homolog B

CTD Direct Evidence: marker/mechanism

NCBI chr 5:173,290,007...173,307,663
Ensembl chr 5:180,548,381...180,565,094

G

ribonuclease A family member 4

CTD Direct Evidence: marker/mechanism

NCBI chr14:1,548,729...1,564,819
Ensembl chr14:19,620,758...19,621,201

G

ribonuclease L

CTD Direct Evidence: marker/mechanism

NCBI chr 1:158,092,346...158,108,026
Ensembl chr 1:161,741,645...161,760,045

G

ring finger protein 39

CTD Direct Evidence: marker/mechanism

NCBI chr 6:29,848,055...29,853,659

G

roundabout guidance receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:76,013,780...77,764,156
Ensembl chr 3:79,030,223...79,632,309

G

rabphilin 3A like (without C2 domains)

CTD Direct Evidence: marker/mechanism

NCBI chr17:90,816...293,651
Ensembl chr17:146,155...283,278

G

arginine and serine rich protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:24,440,889...24,446,165

G

reticulon 4

CTD Direct Evidence: marker/mechanism

NCBI chr2A:55,129,272...55,207,031

G

receptor transporter protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:46,397,231...46,400,221
Ensembl chr 3:47,502,087...47,505,062

G

retinoid X receptor alpha

NCBI chr 9:105,424,046...105,539,241
Ensembl chr 9:134,082,865...134,144,704

G

S100 calcium binding protein A10

CTD Direct Evidence: marker/mechanism

NCBI chr 1:127,341,974...127,353,054
Ensembl chr 1:130,985,312...130,995,130

G

S100 calcium binding protein A11

CTD Direct Evidence: marker/mechanism

NCBI chr 1:127,391,695...127,396,231
Ensembl chr 1:131,034,588...131,035,882

G

S100 calcium binding protein A6

CTD Direct Evidence: marker/mechanism

NCBI chr 1:128,889,749...128,891,425
Ensembl chr 1:132,518,834...132,520,499

G

S100 calcium binding protein A9

CTD Direct Evidence: marker/mechanism

NCBI chr 1:128,709,175...128,712,461
Ensembl chr 1:132,338,246...132,341,497

G

sphingosine-1-phosphate receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987

G

sterile alpha motif domain containing 11

CTD Direct Evidence: marker/mechanism

G

SAM and SH3 domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr X:118,909,980...118,924,779
Ensembl chr X:129,207,049...129,222,342

G

short chain dehydrogenase/reductase family 42E, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:62,598,730...62,615,766
Ensembl chr16:82,021,008...82,038,332

G

serine dehydratase

CTD Direct Evidence: marker/mechanism

NCBI chr12:110,995,164...111,006,668
Ensembl chr12:114,377,650...114,388,839

G

selenoprotein M

CTD Direct Evidence: marker/mechanism

NCBI chr22:12,128,513...12,131,653
Ensembl chr22:29,966,602...29,969,137

G

selenoprotein P

CTD Direct Evidence: marker/mechanism

NCBI chr 5:67,570,087...67,582,192
Ensembl chr 5:72,619,607...72,627,213

G

selenoprotein W

CTD Direct Evidence: marker/mechanism

NCBI chr19:44,773,154...44,779,649

G

selectin P

protein:increased expression:bone marrow

NCBI chr 1:145,071,094...145,112,851
Ensembl chr 1:148,793,677...148,834,701

G

semaphorin 6D

CTD Direct Evidence: marker/mechanism

NCBI chr15:26,135,344...26,725,571
Ensembl chr15:44,994,073...45,050,169

G

SUMO specific peptidase 2

CTD Direct Evidence: therapeutic

NCBI chr 3:182,606,922...182,655,518
Ensembl chr 3:191,086,488...191,129,572

G

serpin family A member 4

CTD Direct Evidence: marker/mechanism

NCBI chr14:75,185,501...75,194,061
Ensembl chr14:94,517,341...94,525,820

G

serpin family A member 6

CTD Direct Evidence: marker/mechanism

NCBI chr14:74,936,724...74,955,799
Ensembl chr14:94,269,299...94,288,391

G

serpin family A member 7

CTD Direct Evidence: marker/mechanism

NCBI chr X:95,163,842...95,169,230
Ensembl chr X:105,541,475...105,548,132

G

serpin family B member 9

CTD Direct Evidence: marker/mechanism

NCBI chr 6:2,709,188...2,725,592
Ensembl chr 6:2,812,815...2,827,932

G

serpin family C member 1

treatment

associated with Inflammatory Bowel Diseases

NCBI chr 1:149,421,737...149,435,301
Ensembl chr 1:153,126,031...153,139,369

G

serpin family H member 1

CTD Direct Evidence: marker/mechanism

PMID:18376398 PMID:25380136

NCBI chr11:70,621,893...70,632,570

G

seizure related 6 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr17:27,768,229...27,819,257
Ensembl chr17:28,301,359...28,327,354

G

sarcoglycan beta

CTD Direct Evidence: marker/mechanism

NCBI chr 4:71,924,051...71,942,642
Ensembl chr 4:78,476,969...78,491,156

G

serum/glucocorticoid regulated kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:39,897,338...39,924,767
Ensembl chr20:40,997,536...41,018,587

G

SH3 domain binding glutamate rich protein like 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:25,540,781...25,542,558

G

SHC binding and spindle associated 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:26,847,164...26,890,762
Ensembl chr16:45,741,101...45,783,632

G

shisa family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:36,718,938...36,723,924
Ensembl chr 4:42,567,291...42,572,098

G

sialic acid binding Ig like lectin 5

CTD Direct Evidence: marker/mechanism

NCBI chr19:48,557,002...48,575,781

G

sirtuin 1

CTD Direct Evidence: therapeutic

NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069

G

src kinase associated phosphoprotein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:27,309,599...27,505,842
Ensembl chr 7:26,911,734...27,106,285

G

SKI like proto-oncogene

NCBI chr 3:167,372,104...167,411,287
Ensembl chr 3:175,562,007...175,600,181

G

Src like adaptor

CTD Direct Evidence: marker/mechanism

NCBI chr 8:129,690,546...129,757,660
Ensembl chr 8:132,666,411...132,732,669

G

SLAM family member 9

CTD Direct Evidence: marker/mechanism

NCBI chr 1:135,303,534...135,306,012
Ensembl chr 1:139,224,139...139,226,614

G

solute carrier family 10 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:50,369,663...50,390,984
Ensembl chr14:69,240,602...69,261,904

G

solute carrier family 12 member 3

protein:altered expression:kidney (rat)

NCBI chr16:37,142,797...37,193,713
Ensembl chr16:56,276,049...56,324,528

G

solute carrier family 15 member 3

CTD Direct Evidence: marker/mechanism

NCBI chr11:56,200,278...56,215,451
Ensembl chr11:59,640,970...59,655,535

G

solute carrier family 17 member 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 6:25,616,393...25,665,603
Ensembl chr 6:26,289,651...26,323,698

G

solute carrier family 17 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:25,746,100...25,764,029
Ensembl chr 6:26,404,163...26,421,879

G

solute carrier family 19 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:144,946,248...144,968,736
Ensembl chr 1:148,668,687...148,690,713

G

solute carrier family 20 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr2A:89,394,161...89,412,141
Ensembl chr2A:113,657,901...113,679,575

G

solute carrier family 22 member 23

CTD Direct Evidence: marker/mechanism

NCBI chr 6:3,107,790...3,294,510
Ensembl chr 6:3,296,927...3,481,350

G

solute carrier family 22 member 25

CTD Direct Evidence: marker/mechanism

NCBI chr11:58,520,224...58,596,848
Ensembl chr11:61,869,537...61,935,088
Ensembl chr11:61,869,537...61,935,088

G

solute carrier family 22 member 8

CTD Direct Evidence: marker/mechanism

NCBI chr11:58,345,026...58,368,089
Ensembl chr11:61,696,354...61,719,413

G

solute carrier family 23 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:134,737,344...134,756,153
Ensembl chr 5:140,859,984...140,877,214

G

solute carrier family 25 member 13

CTD Direct Evidence: marker/mechanism

NCBI chr 7:88,072,139...88,273,470
Ensembl chr 7:101,658,507...101,859,587

G

solute carrier family 25 member 30

CTD Direct Evidence: marker/mechanism

NCBI chr13:27,599,247...27,620,917

G

solute carrier family 25 member 4

CTD Direct Evidence: marker/mechanism

NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549

G

solute carrier family 37 member 4

CTD Direct Evidence: marker/mechanism

NCBI chr11:113,862,537...113,869,447
Ensembl chr11:117,792,700...117,799,269

G

solute carrier family 39 member 6

CTD Direct Evidence: marker/mechanism

NCBI chr18:29,361,261...29,382,115
Ensembl chr18:32,919,878...32,940,694

G

solute carrier family 39 member 8

CTD Direct Evidence: marker/mechanism

NCBI chr 4:94,675,458...94,770,380
Ensembl chr 4:105,339,488...105,433,568

G

solute carrier family 43 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:1,557,305...1,612,968
Ensembl chr17:1,455,767...1,508,443

G

solute carrier family 44 member 2 (CTL2 blood group)

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,154,320...10,196,898
Ensembl chr19:10,815,820...10,857,693

G

solute carrier family 46 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:28,367,674...28,379,618
Ensembl chr17:28,870,678...28,877,632

G

solute carrier family 4 member 4

CTD Direct Evidence: marker/mechanism

NCBI chr 4:52,659,221...52,994,053
Ensembl chr 4:59,002,200...59,385,608

G

solute carrier family 66 member 3

CTD Direct Evidence: marker/mechanism

NCBI chr2A:11,144,034...11,166,471
Ensembl chr2A:11,293,960...11,315,854

G

solute carrier family 7 member 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:10,791,600...10,877,082
Ensembl chr13:28,837,200...28,907,403

G

SMAD family member 1

NCBI chr 4:137,822,269...137,899,700
Ensembl chr 4:149,481,836...149,558,135

G

SMAD family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530

G

SMAD family member 3

treatment

NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185

G

SMAD family member 4

treatment

CTD Direct Evidence: marker/mechanism

PMID:16570350 PMID:19824107

NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:47,487,948...47,683,623
Ensembl chr 3:48,590,221...48,781,248

G

structural maintenance of chromosomes 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:75,273,163...75,323,486
Ensembl chr 9:103,402,967...103,449,949

G

structural maintenance of chromosomes 5

CTD Direct Evidence: marker/mechanism

NCBI chr 9:54,446,863...54,543,249

G

SPARC related modular calcium binding 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:50,472,951...50,622,267
Ensembl chr14:69,345,185...69,493,887

G

SPARC related modular calcium binding 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:166,430,178...166,664,577
Ensembl chr 6:171,366,929...171,589,084

G

synaptosome associated protein 23

CTD Direct Evidence: marker/mechanism

NCBI chr15:21,456,247...21,494,340
Ensembl chr15:39,612,445...39,650,759

G

synaptosome associated protein 29

CTD Direct Evidence: marker/mechanism

NCBI chr22:3,082,622...3,115,325
Ensembl chr22:19,572,618...19,605,931

G

sorting nexin 7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:101,314,484...101,417,388
Ensembl chr 1:100,037,161...100,138,877

G

sterol O-acyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:154,776,305...154,840,594
Ensembl chr 1:158,464,886...158,524,909

G

suppressor of cytokine signaling 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:10,196,432...10,198,205

G

suppressor of cytokine signaling 2

CTD Direct Evidence: marker/mechanism

NCBI chr12:91,115,319...91,134,191
Ensembl chr12:94,514,455...94,520,748

G

SRY-box transcription factor 4

CTD Direct Evidence: marker/mechanism

NCBI chr 6:21,422,846...21,427,779

G

SP140 nuclear body protein

CTD Direct Evidence: marker/mechanism

NCBI chr2B:117,477,923...117,565,367
Ensembl chr2B:236,279,460...236,366,314

G

secreted protein acidic and cysteine rich

mRNA:increased expression:liver, fat cell
CTD Direct Evidence: marker/mechanism|therapeutic

PMID:8786698 PMID:18615449 PMID:25380136

RGD:2300030 RGD:2300071

NCBI chr 5:147,087,903...147,112,466
Ensembl chr 5:153,090,181...153,115,750

G

secreted phosphoprotein 1

NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935

G

splA/ryanodine receptor domain and SOCS box containing 4

CTD Direct Evidence: marker/mechanism

NCBI chr 3:138,085,136...138,181,747
Ensembl chr 3:145,682,533...145,779,049

G

spectrin alpha, non-erythrocytic 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:99,674,819...99,755,973
Ensembl chr 9:128,341,739...128,422,971

G

steroid 5 alpha-reductase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:6,953,795...6,996,010
Ensembl chr 5:6,629,093...6,664,264

G

sterol regulatory element binding transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045

G

serglycin

CTD Direct Evidence: marker/mechanism

NCBI chr10:65,554,873...65,572,108
Ensembl chr10:68,089,392...68,106,250

G

sorcin

CTD Direct Evidence: marker/mechanism

NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029

G

serine racemase

CTD Direct Evidence: marker/mechanism

NCBI chr17:2,294,440...2,316,244
Ensembl chr17:2,182,839...2,200,704

G

ST14 transmembrane serine protease matriptase

CTD Direct Evidence: marker/mechanism

NCBI chr11:125,001,771...125,021,371
Ensembl chr11:128,888,124...128,913,559

G

SH3 and cysteine rich domain 3

CTD Direct Evidence: marker/mechanism

NCBI chr12:31,674,537...31,683,917
Ensembl chr12:31,928,955...31,936,251

G

StAR related lipid transfer domain containing 13

CTD Direct Evidence: marker/mechanism

NCBI chr13:14,359,252...14,607,742
Ensembl chr13:32,789,587...33,038,606

G

signal transducer and activator of transcription 3

treatment

NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067

G

staufen double-stranded RNA binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:69,958,735...70,283,591
Ensembl chr 8:71,606,583...71,929,167

G

STEAP4 metalloreductase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:80,263,528...80,299,470
Ensembl chr 7:93,918,327...93,948,754

G

serine/threonine kinase 10

CTD Direct Evidence: marker/mechanism

NCBI chr 5:167,396,133...167,539,286
Ensembl chr 5:174,311,171...174,455,082

G

sulfotransferase family 1E member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:54,377,681...54,396,619
Ensembl chr 4:60,713,392...60,733,229

G

sulfotransferase family 2A member 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:44,864,747...44,880,688
Ensembl chr19:53,517,248...53,532,573

G

synergin gamma

CTD Direct Evidence: marker/mechanism

NCBI chr17:19,467,539...19,560,618
Ensembl chr17:19,768,058...19,860,323

G

transgelin 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:135,269,954...135,277,421
Ensembl chr 1:139,190,519...139,197,953

G

transporter 2, ATP binding cassette subfamily B member

CTD Direct Evidence: marker/mechanism

NCBI chr 6:32,394,586...32,408,297
Ensembl chr 6:33,507,332...33,523,750

G

Tax1 binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr17:3,713,211...3,718,959
Ensembl chr17:3,709,600...3,715,342

G

TBC1 domain family member 9

CTD Direct Evidence: marker/mechanism

NCBI chr 4:132,982,357...133,118,036
Ensembl chr 4:144,293,141...144,426,374

G

transcription factor 20

CTD Direct Evidence: marker/mechanism

NCBI chr22:23,055,704...23,240,003
Ensembl chr22:41,124,871...41,180,013

G

transcription factor 4

CTD Direct Evidence: marker/mechanism

NCBI chr18:48,603,069...48,969,010
Ensembl chr18:51,938,357...52,352,030

G

telomerase reverse transcriptase

protein:increased expression, increased localization:nucleus

Ensembl chr 5:1,300,960...1,338,872

G

testin LIM domain protein

CTD Direct Evidence: marker/mechanism

NCBI chr 7:108,176,519...108,224,816
Ensembl chr 7:120,873,762...120,922,333

G

transferrin

CTD Direct Evidence: marker/mechanism

PMID:15650968 PMID:22464783

NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476

G

transcription factor EC

CTD Direct Evidence: marker/mechanism

NCBI chr 7:107,900,876...107,996,752

G

tissue factor pathway inhibitor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:85,835,141...85,839,515
Ensembl chr 7:99,426,006...99,431,099

G

transforming growth factor beta 1

treatment
onset

protein:increased expression:liver
mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism|therapeutic
associated with Chemical and Drug Induced Liver Injury
associated with extrahepatic cholestasis

PMID:12586293 PMID:15772939 PMID:16009107 PMID:16579972 PMID:26806094 More...

RGD:14985231 RGD:14985232 RGD:14985234 RGD:14995475 RGD:1601595 RGD:39939037

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

G

transforming growth factor beta 3

CTD Direct Evidence: marker/mechanism

NCBI chr14:56,516,697...56,542,097
Ensembl chr14:75,359,505...75,382,412

G

transforming growth factor beta receptor 1

protein:increased expression:liver

PMID:15723089 PMID:16009107

RGD:1601595 RGD:2302027

NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748

G

transforming growth factor beta receptor 2

treatment

CTD Direct Evidence: therapeutic

PMID:15942678 PMID:16627068 PMID:30346985

RGD:151665755 RGD:1579923

NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856

G

tyrosine hydroxylase

mRNA:decreased expression:superior mesenteric artery (rat)

NCBI chr11:2,204,820...2,212,750
Ensembl chr11:2,231,248...2,242,433

G

thrombomodulin

protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:21112949 PMID:25380136

NCBI chr20:22,992,341...22,996,415
Ensembl chr20:23,345,917...23,347,812

G

thymocyte nuclear protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:129,101,422...129,106,521
Ensembl chr11:132,958,850...132,963,911

G

TIA1 cytotoxic granule associated RNA binding protein like 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:116,142,127...116,165,631
Ensembl chr10:119,561,786...119,585,157

G

TIMP metallopeptidase inhibitor 1

mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism

PMID:8707259 PMID:16507762 PMID:16718785 PMID:16762003 PMID:21163135 More...

NCBI chr X:40,018,190...40,022,636
Ensembl chr X:47,914,906...47,919,419

G

TIMP metallopeptidase inhibitor 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649

G

triokinase and FMN cyclase

CTD Direct Evidence: marker/mechanism

NCBI chr11:56,633,046...56,648,276
Ensembl chr11:60,002,530...60,010,762

G

toll like receptor 2

treatment

PMID:22683883 PMID:27601294

RGD:18182936 RGD:7241092

NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331

G

toll like receptor 3

NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728

G

toll like receptor 4

treatment

CTD Direct Evidence: marker/mechanism

PMID:22683883 PMID:25380136 PMID:27601294

RGD:18182936 RGD:7241092

NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711

G

transmembrane 6 superfamily member 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:62,467,207...62,498,060
Ensembl chr15:80,995,993...81,025,503

G

transmembrane BAX inhibitor motif containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr2B:105,533,578...105,551,969
Ensembl chr2B:224,131,478...224,143,170

G

transmembrane protein 106A

CTD Direct Evidence: marker/mechanism

NCBI chr17:14,111,300...14,119,486
Ensembl chr17:14,343,676...14,351,146

G

transmembrane protein 165

CTD Direct Evidence: marker/mechanism

NCBI chr 4:68,484,896...68,541,808
Ensembl chr 4:75,075,427...75,104,629

G

transmembrane protein 178A

CTD Direct Evidence: marker/mechanism

NCBI chr2A:39,702,860...39,755,605

G

transmembrane protein 184B

CTD Direct Evidence: marker/mechanism

NCBI chr22:19,129,580...19,184,852
Ensembl chr22:36,957,324...37,010,074

G

transmembrane protein 43

CTD Direct Evidence: marker/mechanism

NCBI chr 3:14,043,369...14,062,064
Ensembl chr 3:14,383,983...14,400,587

G

transmembrane protein 65

CTD Direct Evidence: marker/mechanism

NCBI chr 8:120,993,261...121,059,743

G

thymosin beta 10

CTD Direct Evidence: marker/mechanism

NCBI chr2A:84,958,267...84,959,382
Ensembl chr2A:86,517,393...86,517,799

G

tumor necrosis factor

treatment

mRNA:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism

PMID:16085334 PMID:24383550 PMID:28465467

RGD:10450610 RGD:39939037

NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381

G

TNF alpha induced protein 8

CTD Direct Evidence: marker/mechanism

NCBI chr 5:114,657,140...114,784,819
Ensembl chr 5:120,442,500...120,569,877

G

TNF receptor superfamily member 12A

CTD Direct Evidence: marker/mechanism

NCBI chr16:1,962,179...1,964,223
Ensembl chr16:3,134,577...3,136,581

G

torsin family 4 member A

CTD Direct Evidence: marker/mechanism

NCBI chr 9:108,337,814...108,342,723
Ensembl chr 9:137,307,626...137,310,283

G

tropomyosin 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:41,989,239...42,018,520
Ensembl chr15:60,286,587...60,315,530

G

tropomyosin 4

CTD Direct Evidence: marker/mechanism

NCBI chr19:15,557,683...15,593,143
Ensembl chr19:16,540,805...16,575,312

G

TRAF-type zinc finger domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:109,722,290...109,749,731
Ensembl chr12:113,117,145...113,144,336

G

trafficking kinesin protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr2B:88,630,665...88,705,709
Ensembl chr2B:206,785,541...206,861,102

G

tribbles pseudokinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr20:583,267...605,416
Ensembl chr20:359,879...375,486

G

tripartite motif containing 24

CTD Direct Evidence: marker/mechanism

NCBI chr 7:130,420,334...130,547,489
Ensembl chr 7:142,909,009...143,036,526

G

tripartite motif containing 59

CTD Direct Evidence: marker/mechanism

NCBI chr 3:157,458,982...157,471,521

G

transient receptor potential cation channel subfamily V member 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:3,612,781...3,658,608
Ensembl chr17:3,609,952...3,637,579

G

TSC22 domain family member 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:25,597,530...25,743,522
Ensembl chr 3:198,325,494...198,469,869

G

tetraspanin 8

CTD Direct Evidence: marker/mechanism

NCBI chr12:68,653,209...68,686,565
Ensembl chr12:71,417,577...71,450,873

G

translocator protein

CTD Direct Evidence: marker/mechanism

NCBI chr22:24,034,918...24,046,370
Ensembl chr22:42,233,619...42,244,930

G

thiosulfate sulfurtransferase like domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr 6:97,361,666...97,426,467
Ensembl chr 6:101,249,439...101,278,532

G

tetratricopeptide repeat domain 36

CTD Direct Evidence: marker/mechanism

NCBI chr11:113,364,559...113,368,586
Ensembl chr11:117,295,191...117,298,928

G

tubulin beta 6 class V

CTD Direct Evidence: marker/mechanism

NCBI chr18:1,998,428...2,020,202

G

tumor suppressor candidate 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:14,795,921...14,988,566
Ensembl chr 8:11,603,037...11,745,152

G

transmembrane immune signaling adaptor TYROBP

CTD Direct Evidence: marker/mechanism

NCBI chr19:32,821,279...32,825,488
Ensembl chr19:41,570,683...41,575,226

G

U2 snRNP associated SURP domain containing

CTD Direct Evidence: marker/mechanism

NCBI chr 3:140,035,004...140,092,852

G

ubiquitin D

CTD Direct Evidence: marker/mechanism

NCBI chr 6:29,359,680...29,364,014
Ensembl chr 6:30,018,444...30,022,814

G

UDP-glucose ceramide glucosyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 9:83,024,602...83,065,017
Ensembl chr 9:111,184,478...111,222,613

G

unc-5 family C-terminal like

CTD Direct Evidence: marker/mechanism

NCBI chr 6:40,615,697...40,627,997
Ensembl chr 6:41,923,872...41,936,198

G

unc-93 homolog B1, TLR signaling regulator

CTD Direct Evidence: marker/mechanism

NCBI chr11:63,073,076...63,086,078
Ensembl chr11:66,382,059...66,394,541

G

vasodilator stimulated phosphoprotein

CTD Direct Evidence: marker/mechanism

NCBI chr19:42,457,222...42,476,688
Ensembl chr19:51,053,567...51,072,553

G

vav guanine nucleotide exchange factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:5,805,121...5,888,203
Ensembl chr19:6,726,578...6,806,112

G

vascular endothelial growth factor A

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:18416461 PMID:18458672

NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353

G

vimentin

CTD Direct Evidence: marker/mechanism
associated with Schistosomiasis Japonica; mRNA:increased expression:liver (rat)

PMID:25380136 PMID:29323718

NCBI chr10:17,546,389...17,554,702
Ensembl chr10:17,818,285...17,826,642

G

vasoactive intestinal peptide receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:42,407,591...42,442,565
Ensembl chr 3:42,670,195...42,705,170

G

VOPP1 WW domain binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr 7:56,061,704...56,163,517
Ensembl chr 7:56,372,027...56,463,310

G

V-set immunoregulatory receptor

CTD Direct Evidence: marker/mechanism

NCBI chr10:68,218,230...68,243,687
Ensembl chr10:70,742,062...70,767,613

G

von Willebrand factor

CTD Direct Evidence: marker/mechanism
protein:increased expression:liver:

PMID:7531171 PMID:28527913

NCBI chr12:6,073,836...6,249,806
Ensembl chr12:5,990,612...6,165,153

G

WAP four-disulfide core domain 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:41,803,624...41,815,442
Ensembl chr20:42,893,345...42,905,122

G

WAS/WASL interacting protein family member 1

CTD Direct Evidence: marker/mechanism

NCBI chr2B:61,837,128...61,960,468
Ensembl chr2B:179,290,685...179,316,695

G

Wnt ligand secretion mediator

CTD Direct Evidence: marker/mechanism

NCBI chr 1:67,336,009...67,470,265
Ensembl chr 1:69,318,742...69,425,652

G

X-prolyl aminopeptidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr X:118,869,083...118,900,639
Ensembl chr X:129,165,882...129,197,347

G

Y-box binding protein 1

CTD Direct Evidence: therapeutic

NCBI chr 1:41,982,365...42,002,430
Ensembl chr 1:43,360,052...43,380,313

G

yippee like 3

CTD Direct Evidence: marker/mechanism

Ensembl chr16:30,467,490...30,471,256

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

CTD Direct Evidence: marker/mechanism

NCBI chr 7:67,661,589...67,693,814

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

CTD Direct Evidence: marker/mechanism

NCBI chr 8:97,560,251...97,595,117
Ensembl chr 8:99,730,393...99,762,990

G

zinc finger and BTB domain containing 4

CTD Direct Evidence: marker/mechanism

NCBI chr17:7,491,971...7,516,823
Ensembl chr17:7,477,848...7,497,062

G

zinc finger DHHC-type palmitoyltransferase 13

CTD Direct Evidence: marker/mechanism

NCBI chr11:19,143,181...19,202,424
Ensembl chr11:19,056,902...19,115,261

G

zinc finger DHHC-type palmitoyltransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:16,368,954...16,437,623
Ensembl chr 8:13,343,011...13,380,803

G

zinc finger E-box binding homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chr2B:15,325,094...15,460,908
Ensembl chr2B:148,460,904...148,596,500

G

ZFP37 zinc finger protein

CTD Direct Evidence: marker/mechanism

NCBI chr 9:84,162,037...84,181,780
Ensembl chr 9:112,319,791...112,334,702

G

zinc finger FYVE-type containing 16

CTD Direct Evidence: marker/mechanism

NCBI chr 5:34,837,410...34,910,416
Ensembl chr 5:35,111,723...35,183,028

G

zinc finger protein 705A

CTD Direct Evidence: marker/mechanism

NCBI chr 8:11,570,038...11,577,621

Term paths to the root

Path 1
Term	Annotations
disease	17996
disease of anatomical entity	15260
endocrine system disease	5967
liver disease	2700
liver cirrhosis	1095
Experimental Liver Cirrhosis	879
Path 2
Term	Annotations
disease	17996
disease of anatomical entity	15260
gastrointestinal system disease	6469
hepatobiliary disease	2805
liver disease	2700
liver cirrhosis	1095
Experimental Liver Cirrhosis	879

paths to the root