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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Acanthamoeba Keratitis
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Accession:DOID:9001552 term browser browse the term
Definition:Infection of the cornea by an ameboid protozoan which may cause corneal ulceration leading to blindness.
Synonyms:exact_synonym: Acanthamoeba Keratitides
 primary_id: MESH:D015823
 xref: EFO:0007126


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Acanthamoeba Keratitis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll-like receptor 4 ISO mRNA,protein:increased expression:cornea RGD PMID:21155840 RGD:7777095 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18300
    disease by infectious agent 2198
      parasitic infectious disease 318
        Parasitic Eye Infections 13
          Acanthamoeba Keratitis 1
Path 2
Term Annotations click to browse term
  disease 18300
    disease of anatomical entity 15630
      nervous system disease 13500
        Neurologic Manifestations 9788
          sensory system disease 6744
            eye disease 3459
              Eye Infections 58
                Parasitic Eye Infections 13
                  Acanthamoeba Keratitis 1
paths to the root