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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Cerebral Toxoplasmosis
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Accession:DOID:9001479 term browser browse the term
Definition:Infections of the BRAIN caused by the protozoan TOXOPLASMA gondii that primarily arise in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES (see also AIDS-RELATED OPPORTUNISTIC INFECTIONS). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include SEIZURES, altered mentation, headache, focal neurologic deficits, and INTRACRANIAL HYPERTENSION. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)
Synonyms:exact_synonym: Central Nervous System Toxoplasmosis;   Intracranial Toxoplasmosis;   Neurotoxoplasmosis;   Toxoplasmoses, Cerebral
 primary_id: MESH:D016781
 alt_id: RDO:0006999
For additional species annotation, visit the Alliance of Genome Resources.



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Cerebral Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO RGD PMID:20156658 RGD:40902838 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18032
    disease by infectious agent 2083
      parasitic infectious disease 321
        Central Nervous System Parasitic Infections 20
          Central Nervous System Protozoal Infections 15
            Cerebral Toxoplasmosis 1
Path 2
Term Annotations click to browse term
  disease 18032
    disease of anatomical entity 17412
      Immune & Inflammatory Diseases 5046
        Inflammation 2742
          Suppuration 101
            Abscess 11
              Brain Abscess 2
                Cerebral Toxoplasmosis 1
paths to the root