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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Urinary Incontinence, Stress
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Accession:DOID:9001330 term browser browse the term
Definition:Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.
Synonyms:primary_id: MESH:D014550;   RDO:0006792


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Urinary Incontinence, Stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eln elastin IEP RGD PMID:19878076 RGD:7207866 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Loxl1 lysyl oxidase-like 1 ISO DNA:SNPs, haplotype:exon, intron:rs1048661, rs2165241 (human) RGD PMID:22765198 RGD:7394729 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356 		JBrowse link
female stress incontinence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs2 regulator of G-protein signaling 2 IEP RGD PMID:18372098 RGD:13524574 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21112
    Pathological Conditions, Signs and Symptoms 13291
      Signs and Symptoms 10731
        Urological Manifestations 608
          Lower Urinary Tract Symptoms 17
            Urinary Incontinence 5
              Urinary Incontinence, Stress 3
                female stress incontinence 1
paths to the root