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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Dyspepsia
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Accession:DOID:9001204 term browser browse the term
Definition:Impaired digestion, especially after eating.
Synonyms:exact_synonym: Dyspepsia, indigestion;   Indigestion;   dyspepsias;   indigestions
 primary_id: MESH:D004415
 alt_id: DOID:2321
 xref: NCI:C26756
For additional species annotation, visit the Alliance of Genome Resources.


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Dyspepsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IEP protein:increased expression:central nucleus of amygdala, paraventricular hypothalamic nucleus (rat) RGD PMID:21589865 RGD:5490556 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A ISO DNA:SNP:promoter:c.-42C>T(human) RGD PMID:22014438 RGD:6480658 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link
G Ifng interferon gamma treatment IEP RGD PMID:28854971 RGD:14975120 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 no_association ISO DNA:SNP:promoter:-819C>A (rs1800871)(human)
DNA:SNP:promoter:-1082G>A (rs1800896)(human)
RGD PMID:28965252, PMID:28965252 RGD:14975154, RGD:14975154 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO DNA:polymorphism: :
DNA:haplotypes, multiple:
RGD PMID:22014438, PMID:24720453 RGD:6480658, RGD:36947385 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16045
    Pathological Conditions, Signs and Symptoms 8735
      Signs and Symptoms 5235
        Digestive Signs and Symptoms 117
          Dyspepsia 5
Path 2
Term Annotations click to browse term
  disease 16045
    disease of anatomical entity 15292
      gastrointestinal system disease 4623
        Gastrointestinal Diseases 2542
          stomach disease 543
            functional gastric disease 7
              Dyspepsia 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.