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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Nociceptive Pain
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Accession:DOID:9001048 term browser browse the term
Definition:Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.
Synonyms:exact_synonym: Nociceptive Pains;   Somatic Pain;   Somatic Pains;   Tissue Pain;   Tissue Pains
 primary_id: MESH:D059226

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Nociceptive Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grm8 glutamate metabotropic receptor 8 ISO RGD PMID:17113112 RGD:6771186 NCBI chrNW_004936479:13,768,014...14,504,387
Ensembl chrNW_004936479:13,770,088...14,494,569 		JBrowse link
G Pdyn prodynorphin ISO RGD PMID:25663984 RGD:401851903 NCBI chrNW_004936485:16,559,371...16,571,461
Ensembl chrNW_004936485:16,559,217...16,571,678 		JBrowse link
G Pomc proopiomelanocortin ISO RGD PMID:21380811 RGD:5508807 NCBI chrNW_004936493:7,060,747...7,065,276
Ensembl chrNW_004936493:7,061,587...7,065,109 		JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:21371033 RGD:6483537 NCBI chrNW_004936518:1,903,636...1,916,746
Ensembl chrNW_004936518:1,903,725...1,916,746 		JBrowse link
G Ptgis prostaglandin I2 synthase ameliorates ISO RGD PMID:26611322 RGD:11536046 NCBI chrNW_004936514:4,775,884...4,814,574
Ensembl chrNW_004936514:4,791,031...4,812,027 		JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:19467283 RGD:5685608 NCBI chrNW_004936489:5,425,778...5,434,483
Ensembl chrNW_004936489:5,425,726...5,434,785 		JBrowse link
Visceral Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A ISO RGD PMID:20047711 RGD:6480482 NCBI chrNW_004936486:1,837,785...1,841,019
Ensembl chrNW_004936486:1,838,176...1,839,630 		JBrowse link
G Bdnf brain derived neurotrophic factor ISO associated with Colitis; protein:increased expression:dorsal root ganglion: RGD PMID:19932037 PMID:21997550 RGD:8655978 RGD:8657331 NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014 		JBrowse link
G Ephb2 EPH receptor B2 ameliorates ISO RGD PMID:33880135 RGD:127285657 NCBI chrNW_004936474:8,109,800...8,203,106
Ensembl chrNW_004936474:8,109,031...8,203,106 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment ISO DNA:haplotype RGD PMID:25783971 RGD:401700391 NCBI chrNW_004936697:232,048...275,420 JBrowse link
G Penk proenkephalin treatment ISO RGD PMID:23316929 RGD:10003040 NCBI chrNW_004936496:3,016,247...3,021,726
Ensembl chrNW_004936496:3,016,218...3,021,738 		JBrowse link
G Trpa1 transient receptor potential cation channel subfamily A member 1 ISO associated with Colitis; RGD PMID:23099257 RGD:10043788 NCBI chrNW_004936648:1,094,460...1,141,394
Ensembl chrNW_004936648:1,094,460...1,141,394 		JBrowse link
G Trpc4 transient receptor potential cation channel subfamily C member 4 ISO RGD PMID:24388923 RGD:13825245 NCBI chrNW_004936472:31,710,873...31,909,106
Ensembl chrNW_004936472:31,711,040...31,843,876 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16465
    Pathological Conditions, Signs and Symptoms 11287
      Signs and Symptoms 9356
        Neurologic Manifestations 9046
          Pain 299
            Nociceptive Pain 13
              Visceral Pain 7
paths to the root