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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Nociceptive Pain
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Accession:DOID:9001048 term browser browse the term
Definition:Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.
Synonyms:exact_synonym: Nociceptive Pains;   Somatic Pain;   Somatic Pains;   Tissue Pain;   Tissue Pains
 primary_id: MESH:D059226;   RDO:0009997
For additional species annotation, visit the Alliance of Genome Resources.



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Nociceptive Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grm8 glutamate metabotropic receptor 8 ISO RGD PMID:17113112 RGD:6771186 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
JBrowse link
G Pomc proopiomelanocortin ISO RGD PMID:21380811 RGD:5508807 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:21371033 RGD:6483537 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Vip vasoactive intestinal peptide IDA RGD PMID:19467283 RGD:5685608 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
JBrowse link
Visceral Pain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:20047711 RGD:6480482 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO associated with Colitis; protein:increased expression:dorsal root ganglion: RGD PMID:21997550 PMID:19932037 RGD:8655978, RGD:8657331 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Ephb2 Eph receptor B2 ameliorates ISO RGD PMID:33880135 RGD:127285657 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
JBrowse link
G Penk proenkephalin treatment ISO RGD PMID:23316929 RGD:10003040 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP associated with Colitis; RGD PMID:23099257 RGD:10043788 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 IMP RGD PMID:24388923 RGD:13825245 NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768
JBrowse link
G Trpc4Tn(sb-T2/Bart3)2.192Mcwi transient receptor potential cation channel, subfamily C, member 4; transposon insertion 2.192, Medical College of Wisconsin IMP RGD PMID:24388923 RGD:13825245

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17435
    Pathological Conditions, Signs and Symptoms 10360
      Signs and Symptoms 6553
        Neurologic Manifestations 5497
          Pain 315
            Nociceptive Pain 15
              Visceral Pain 11
paths to the root