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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Intestinal Fistula
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Accession:DOID:9001015 term browser browse the term
Definition:An abnormal anatomical passage between the INTESTINE, and another segment of the intestine or other organs. External intestinal fistula is connected to the SKIN (enterocutaneous fistula). Internal intestinal fistula can be connected to a number of organs, such as STOMACH (gastrocolic fistula), the BILIARY TRACT (cholecystoduodenal fistula), or the URINARY BLADDER of the URINARY TRACT (colovesical fistula). Risk factors include inflammatory processes, cancer, radiation treatment, and surgical misadventures (MEDICAL ERRORS).
Synonyms:exact_synonym: Cholecystoduodenal Fistula;   Colovesical Fistula;   Enterocutaneous Fistula
 primary_id: MESH:D007412;   RDO:0005899
For additional species annotation, visit the Alliance of Genome Resources.


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Intestinal Fistula term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 IEP mRNA, protein:increased expression:colon (rat) RGD PMID:12654563 RGD:4144044 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16035
    disease of anatomical entity 15289
      gastrointestinal system disease 4633
        Digestive System Fistula 51
          Intestinal Fistula 1
            anal fistula + 0
Path 2
Term Annotations click to browse term
  disease 16035
    disease of anatomical entity 15289
      gastrointestinal system disease 4633
        Gastrointestinal Diseases 2554
          intestinal disease 1515
            Intestinal Fistula 1
              anal fistula + 0
paths to the root