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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:necrotizing soft tissue infection
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Accession:DOID:9000992 term browser browse the term
Definition:A bacterial infection of any layer within the soft tissue compartments associated with necrosis. The condition is often accompanied by septic shock, and the extensive inflammatory response is thought to be a primary cause of mortality.
Synonyms:exact_synonym: NSTI
 xref: PMID:26880104



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necrotizing soft tissue infection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptx3 pentraxin 3 severity ISO protein:decreased expression:plasma (human) RGD PMID:26880104 RGD:38508899 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21121
    disease by infectious agent 2212
      Bacterial Infections and Mycoses 1072
        Soft Tissue Infections 1
          necrotizing soft tissue infection 1
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