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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Neoplasm Metastasis
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Accession:DOID:9000965 term browser browse the term
Definition:The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Synonyms:exact_synonym: Metastases;   Metastasis;   Neoplasm Metastases
 primary_id: MESH:D009362
 xref: EFO:0009708;   EFO:0009709;   EFO:0010941



show annotations for term's descendants           Sort by:
Neoplasm Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12015757 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17003774 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631
JBrowse link
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059164 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Ackr3 atypical chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22180778 NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473
JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 ISO associated with pheochromocytoma RGD PMID:29067245 RGD:13831131 NCBI chr 9:54,512,163...54,569,169
Ensembl chr 9:54,512,161...54,569,154
JBrowse link
G Acvr2a activin receptor IIA exacerbates ISO associated with colon cancer;mRNA,protein:decreased expression:colon (human) RGD PMID:30310521 RGD:151361136 NCBI chr 2:48,704,121...48,793,276
Ensembl chr 2:48,704,121...48,793,281
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 ISO associated with colorectal cancer RGD PMID:9772287 RGD:13831353 NCBI chr15:74,388,045...74,461,314
Ensembl chr15:74,388,044...74,461,314
JBrowse link
G Adora2b adenosine A2b receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27590504 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059164 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059164 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403
JBrowse link
G Ahr aryl-hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:21948867 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Akirin2 akirin 2 ISO RGD PMID:18460465 RGD:2306009 NCBI chr 4:34,550,615...34,566,930
Ensembl chr 4:34,550,937...34,566,908
JBrowse link
G Akt2 thymoma viral proto-oncogene 2 ISO associated with Mammary Neoplasms, Experimental RGD PMID:19491266 RGD:2315599 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
JBrowse link
G Alk anaplastic lymphoma kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22986231 PMID:22999080 NCBI chr17:72,174,206...72,911,719
Ensembl chr17:72,175,967...72,911,622
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20061081 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 IMP Liver Metastasis RGD PMID:28272394 RGD:14394499 NCBI chr15:97,141,955...97,145,168
Ensembl chr15:97,142,006...97,145,168
JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: therapeutic CTD PMID:17130448 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Antxr1 anthrax toxin receptor 1 ISO associated with Mammary Neoplasms, Experimental; RGD PMID:22085271 RGD:9684855 NCBI chr 6:87,110,835...87,312,757
Ensembl chr 6:87,110,835...87,312,803
JBrowse link
G Anxa1 annexin A1 treatment ISO
IMP
associated with Mammary Neoplasms, Experimental;protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20308542 PMID:9514092 PMID:20821804 PMID:20821804 PMID:20308542 RGD:2306939, RGD:7421541, RGD:7421541, RGD:7421563 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Anxa4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566
JBrowse link
G Anxa7 annexin A7 ISO associated with Prostatic Neoplasms;protein:decreased expression:prostate gland
associated with Breast Neoplasms;protein:increased expression:breast
RGD PMID:11287641 PMID:15073110 RGD:2292656, RGD:2292655 NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201
JBrowse link
G Apoe apolipoprotein E IMP RGD PMID:22469977 RGD:7771597 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Arid1a AT-rich interaction domain 1A disease_progression IMP in lung; associated with hepatocellular carcinoma RGD PMID:25975202 RGD:125097495 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080
JBrowse link
G Atp6v1c1 ATPase, H+ transporting, lysosomal V1 subunit C1 IMP associated with Mammary Neoplasms, Experimental RGD PMID:24155661 RGD:14700647 NCBI chr15:38,662,096...38,692,688
Ensembl chr15:38,662,177...38,692,690
JBrowse link
G Axl AXL receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206560 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
JBrowse link
G Azin1 antizyme inhibitor 1 ISO associated with stomach cancer;RNA:increased editing:stomach
associated with colorectal cancer;RNA:increased editing:colorectum
RGD PMID:30563560 PMID:29925690 RGD:14700703, RGD:14700704 NCBI chr15:38,487,674...38,523,506
Ensembl chr15:38,487,671...38,519,510
JBrowse link
G Bax BCL2-associated X protein ISO associated with Carcinoma, Infiltrating Duct RGD PMID:17288732 RGD:1643356 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO associated with Breast Neoplasms
associated with Carcinoma, Renal Cell
RGD PMID:16826579 PMID:12810203 RGD:2293020, RGD:2293021 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bmp6 bone morphogenetic protein 6 severity ISO associated with Prostatic Neoplasms;protein:increased expression:bone RGD PMID:16166304 RGD:2289018 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Bmp7 bone morphogenetic protein 7 disease_progression ISO associated with Breast Neoplasms;protein:increased expression:breast
associated with Prostatic Neoplasms;mRNA:increased expression:bone
RGD PMID:17895257 PMID:12539225 RGD:2289029, RGD:2289033 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
JBrowse link
G Braf Braf transforming gene onset ISO associated with Melanoma; DNA:mutations: : RGD PMID:25623140 RGD:11567259 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Brd4 bromodomain containing 4 ISO RGD PMID:23950209 RGD:9586346 NCBI chr17:32,415,246...32,503,717
Ensembl chr17:32,415,248...32,503,696
JBrowse link
G Brms1 breast cancer metastasis-suppressor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27501413 NCBI chr19:5,091,391...5,099,940
Ensembl chr19:5,091,382...5,099,945
JBrowse link
G Bsg basigin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21956400 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803
JBrowse link
G Cab39 calcium binding protein 39 ISO associated with hepatocellular carcinoma; RGD PMID:28605041 RGD:14398832 NCBI chr 1:85,707,796...85,779,298
Ensembl chr 1:85,721,162...85,779,297
JBrowse link
G Cacybp calcyclin binding protein ISO associated with pancreatic neoplasms RGD PMID:18765951 RGD:2326146 NCBI chr 1:160,029,171...160,040,391
Ensembl chr 1:160,029,937...160,040,445
JBrowse link
G Calml3 calmodulin-like 3 ameliorates ISO associated with hepatocellular carcinoma; human cells in mouse model
associated with hepatocellular carcinoma; protein:decreased expression:liver (human)
RGD PMID:29445139 PMID:29445139 RGD:151665319, RGD:151665319 NCBI chr13:3,852,893...3,854,318
Ensembl chr13:3,852,896...3,854,316
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 ISO associated with Pancreatic Neoplasms; mRNA, protein:increased expression:pancreas RGD PMID:19188911 RGD:2326238 NCBI chr 4:122,752,841...122,779,869
Ensembl chr 4:122,752,840...122,779,849
JBrowse link
G Casp3 caspase 3 ISO associated with Breast Neoplasms RGD PMID:18064531 RGD:2293306 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD PMID:12538496 PMID:22580338 PMID:23518002 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cav1 caveolin 1, caveolae protein treatment IMP
ISO
associated with Mammary Neoplasms, Experimental
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20562527 PMID:15355971 PMID:15334058 RGD:2289106, RGD:8661780 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Cbx4 chromobox 4 ISO associated with Carcinoma, Hepatocellular; RGD PMID:24838576 RGD:9586738 NCBI chr11:118,968,399...118,977,067
Ensembl chr11:118,968,399...118,977,047
JBrowse link
G Cbx5 chromobox 5 ISO associated with Lung Neoplasms; RGD PMID:22900142 RGD:9586743 NCBI chr15:103,099,973...103,148,337
Ensembl chr15:103,099,971...103,148,243
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IMP associated with Mammary Neoplasms, Experimental RGD PMID:19629725 RGD:4891450 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 IMP RGD PMID:18941229 RGD:7241810 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment IMP associated with Animal Mammary Neoplasms; RGD PMID:15692764 RGD:14995455 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccn4 cellular communication network factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30723155 NCBI chr15:66,763,337...66,795,050
Ensembl chr15:66,763,169...66,795,050
JBrowse link
G Ccna2 cyclin A2 ISO associated with Seminoma;protein:increased expression:testis RGD PMID:14696091 RGD:2293346 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccnd1 cyclin D1 treatment ISO associated with Carcinoma, Non-Small-Cell Lung;mRNA:splice variant
associated with stomach cancer; human cells in mouse model
RGD PMID:18715616 PMID:27431311 RGD:13434926, RGD:152995400 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd2 cyclin D2 ISO associated with Breast Neoplasms;DNA:hypermethylated:brain RGD PMID:15131050 RGD:2289155 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
JBrowse link
G Ccne1 cyclin E1 disease_progression IDA
ISO
protein:altered processing
associated with non-small cell lung carcinoma
RGD PMID:17671189 PMID:11212263 RGD:2289229, RGD:13673913 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35072892 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cd274 CD274 antigen disease_progression ISO associated with ovarian cancer RGD PMID:23340297 RGD:41410797 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd44 CD44 antigen ISO associated with Carcinoma, Renal Cell;protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
associated with Breast Neoplasm;protein:increased expression:liver
CTD
RGD
PMID:23098472 PMID:18026989 PMID:17991717 RGD:2289347, RGD:2289349 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd82 CD82 antigen ISO associated with Prostatic Neoplasms;DNA:loss of heterozygosity
CTD Direct Evidence: therapeutic
associated with Carcinoma, Hepatocellular;mRNA:decreased expression
associated with Prostatic Neoplasms;mRNA:decreased expression:bone
associated with Carcinoma, Infiltrating Duct;mRNA:decreased expression:brain
CTD
RGD
PMID:20075392 PMID:9254900 PMID:11275982 PMID:12806379 PMID:15592684 More... RGD:2289425, RGD:2289407, RGD:2289402, RGD:2289400, RGD:68869 NCBI chr 2:93,249,447...93,293,295
Ensembl chr 2:93,249,456...93,293,485
JBrowse link
G Cd86 CD86 antigen ISO mRNA:decreased expression:mediastinal lymph node (rat) RGD PMID:18360875 RGD:4892237 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cdh1 cadherin 1 treatment ISO associated with Prostatic Neoplasms
associated with stomach cancer; human cells in mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17520682 PMID:22580338 PMID:18008331 PMID:27431311 RGD:2289488, RGD:152995400 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdh2 cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23876460 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
JBrowse link
G Cdkl2 cyclin dependent kinase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25333262 NCBI chr 5:92,153,933...92,198,479
Ensembl chr 5:92,153,933...92,191,742
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO associated with Melanoma; RGD PMID:9194578 RGD:8662817 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A ISO associated with Paraganglioma, Extra-Adrenal;DNA:hypermethylation RGD PMID:18509008 RGD:8552280 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Cfl1 cofilin 1, non-muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229
JBrowse link
G Cga glycoprotein hormones, alpha subunit ISO associated with Breast Neoplasms;protein:increased expression:serum RGD PMID:6768680 RGD:2293637 NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370
JBrowse link
G Chek1 checkpoint kinase 1 ISO associated with Pancreatic Neoplasms RGD PMID:15448002 RGD:2317235 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IMP associated with prostate adenocarcinoma RGD PMID:17377533 RGD:2298657 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Cic capicua transcriptional repressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869830 NCBI chr 7:24,967,054...24,993,584
Ensembl chr 7:24,967,129...24,993,584
JBrowse link
G Cldn7 claudin 7 ISO RGD PMID:23390083 RGD:9685143 NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711
JBrowse link
G Clic1 chloride intracellular channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr17:35,269,219...35,277,695
Ensembl chr17:35,268,942...35,277,725
JBrowse link
G Clu clusterin ISO associated with Breast Neoplasms RGD PMID:20307318 RGD:8883512 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29179997 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) ISO associated with Prostatic Neoplasms RGD PMID:18510570 RGD:2293638 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Csf1r colony stimulating factor 1 receptor exacerbates ISO
IMP
associated with Prostatic Neoplasms
associated with breast cancer
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:1390197 PMID:18510570 PMID:25005824 RGD:2293638, RGD:150524287 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) ISO CTD Direct Evidence: therapeutic CTD PMID:7543699 PMID:9018096 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Cst3 cystatin C ISO protein:decreased expression:cerebrospinal fluid RGD PMID:12589965 RGD:5686394 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
JBrowse link
G Csta2 cystatin A family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20461718 NCBI chr16:36,041,932...36,077,813
Ensembl chr16:36,041,838...36,077,810
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 disease_progression IMP
ISO
associated with Mammary Neoplasms, Experimental RGD PMID:15701862 PMID:18049334 RGD:4891518, RGD:7204722 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Ctnnb1 catenin beta 1 ISO associated with Prostatic Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29106415 PMID:18008331 RGD:2289488 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctsb cathepsin B ISO protein:increased expression:cerebrospinal fluid RGD PMID:12589965 RGD:5686394 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
JBrowse link
G Ctsd cathepsin D ISO protein:increased expression:oral cavity, oropharynx, hypopharynx (human) RGD PMID:10562684 RGD:1547892 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
JBrowse link
G Ctsh cathepsin H ISO protein:increased expression:cerebrospinal fluid RGD PMID:12589965 RGD:5686394 NCBI chr 9:89,936,320...89,958,148
Ensembl chr 9:89,936,205...89,958,142
JBrowse link
G Ctu1 cytosolic thiouridylase subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr 7:43,321,400...43,327,724
Ensembl chr 7:43,321,440...43,327,722
JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr 8:123,202,882...123,209,831
Ensembl chr 8:123,202,882...123,210,877
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 susceptibility ISO associated with Breast Neoplasms RGD PMID:16627550 RGD:4892015 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 treatment ISO associated with Pancreatic Neoplasms
CTD Direct Evidence: marker/mechanism
associated with Pancreatic Carcinoma
CTD
RGD
PMID:21312072 PMID:23743303 PMID:12761880 PMID:26330165 RGD:2317610, RGD:10398726 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IMP associated with Mammary Neoplasms, Experimental RGD PMID:16885372 RGD:5135487 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ameliorates
severity
disease_progression
ISO
IMP
CTD Direct Evidence: marker/mechanism
associated with lung non-small cell carcinoma;mRNA,protein:increased expression:lung (human)
associated with Otorhinolaryngologic Neoplasms;mRNA,protein:increased expression:Laryngeal and hypopharyngeal tissue (human)
associated with lung non-small cell carcinoma; protein:increased expression:lung (human)
associated with oral squamous cell carcinoma
associated with pancreatic cancer
associated with osteosarcoma;protein:increased expression:bone (human)
human cells in mouse model;associated with lung cancer
associated with lung cancer; human cells in mouse model
CTD
RGD
PMID:21312072 PMID:23743303 PMID:26546437 PMID:16322285 PMID:18487224 More... RGD:152023746, RGD:152177479, RGD:152177478, RGD:152177476, RGD:152177475, RGD:152025556, RGD:152023745, RGD:152023741, RGD:151708730 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28112739 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Dab2ip disabled 2 interacting protein severity ISO associated with colorectal cancer;protein:decreased expression:colorectum (human) RGD PMID:26336990 RGD:11531913 NCBI chr 2:35,448,285...35,621,006
Ensembl chr 2:35,448,278...35,621,006
JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17319784 NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005
JBrowse link
G Daxx Fas death domain-associated protein ISO RGD PMID:23539629 RGD:9587820 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564
JBrowse link
G Dcn decorin ISO associated with Breast Neoplasms RGD PMID:18688028 RGD:2311418 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 severity ISO mRNA:increased expression:ovary (human)
protein:increased expression:bone (human)
RGD PMID:28743276 PMID:29039472 RGD:151347541, RGD:151347601 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Ddr2 discoidin domain receptor family, member 2 ameliorates IAGP associated with melanoma; RGD PMID:24293323 RGD:150429711 NCBI chr 1:169,799,874...169,938,525
Ensembl chr 1:169,799,876...169,938,331
JBrowse link
G Ddx3x DEAD box helicase 3, X-linked ISO human cells in mouse model RGD PMID:26087195 RGD:11096798 NCBI chr  X:13,147,261...13,160,222
Ensembl chr  X:13,147,209...13,160,291
JBrowse link
G Dek DEK proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr13:47,238,243...47,261,134
Ensembl chr13:47,238,251...47,259,677
JBrowse link
G Dhfr dihydrofolate reductase disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19159907 PMID:8149482 RGD:11040442 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561
JBrowse link
G Dio3 deiodinase, iodothyronine type III ISO CTD Direct Evidence: marker/mechanism CTD PMID:26825960 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Dmd dystrophin, muscular dystrophy ISO CTD Direct Evidence: marker/mechanism CTD PMID:24793134 NCBI chr  X:81,858,244...84,248,656
Ensembl chr  X:81,992,476...84,249,747
JBrowse link
G Dnmt3b DNA methyltransferase 3B ISO associated with Uterine Cervical Neoplasms; RGD PMID:22330137 RGD:9589117 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase treatment ISO associated with Colonic Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17611699 PMID:11383214 RGD:11251755 NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573
JBrowse link
G E2f1 E2F transcription factor 1 severity ISO protein:increased expression:bone (human) RGD PMID:29039472 RGD:151347601 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G E2f8 E2F transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27683099 NCBI chr 7:48,516,177...48,531,821
Ensembl chr 7:48,516,177...48,531,344
JBrowse link
G Edn1 endothelin 1 IDA RGD PMID:12941866 RGD:734914 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Ednra endothelin receptor type A IMP associated with Bladder Neoplasms RGD PMID:21183790 RGD:4892282 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 PMID:20562527 NCBI chr 1:63,215,990...63,219,645
Ensembl chr 1:63,215,984...63,219,645
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332
JBrowse link
G Efnb2 ephrin B2 ISO associated with cholangiocarcinoma;protein:increased expression:biliary ductule (human) RGD PMID:25012246 RGD:153305948 NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242
JBrowse link
G Egf epidermal growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21942447 PMID:23064031 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17369752 PMID:17575224 PMID:23867902 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 ISO associated with lung neoplasms;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20940408 PMID:25115793 PMID:20940408 RGD:9589170 NCBI chr17:35,117,427...35,133,049
Ensembl chr17:35,117,445...35,133,028
JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr  X:158,155,174...158,172,617
Ensembl chr  X:158,155,174...158,172,924
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr16:22,924,846...22,932,882
Ensembl chr16:22,926,194...22,932,886
JBrowse link
G Elp3 elongator acetyltransferase complex subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr14:65,767,895...65,830,561
Ensembl chr14:65,767,898...65,830,524
JBrowse link
G Eml4 echinoderm microtubule associated protein like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22986231 PMID:22999080 NCBI chr17:83,658,341...83,787,790
Ensembl chr17:83,658,360...83,787,790
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26037280 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
JBrowse link
G Epcam epithelial cell adhesion molecule ISO RGD PMID:23390083 RGD:9685143 NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16699298 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Epor erythropoietin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16699298 NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO rat gene in a mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16984552 PMID:11238891 RGD:734938 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO associated with Prostatic Neoplasms;protein:alternative form
associated with lung adenocarcinoma
CTD Direct Evidence: marker/mechanism
associated with Prostatic Neoplasms;protein:increased expression, altered localization:bone, nucleus
CTD
RGD
PMID:28114269 PMID:18559590 PMID:26254096 PMID:17634423 RGD:2298500, RGD:126790470, RGD:2289944 NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO associated with lung adenocarcinoma RGD PMID:26254096 RGD:126790470 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 disease_progression ISO associated with Melanoma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20801905 PMID:26202595 RGD:11252177 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449
JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20372803 NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481
JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569
JBrowse link
G Esr1 estrogen receptor 1 (alpha) ISO CTD Direct Evidence: marker/mechanism CTD PMID:20104649 PMID:35044086 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Etv4 ets variant 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869830 NCBI chr11:101,660,573...101,677,963
Ensembl chr11:101,660,568...101,676,197
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO associated with stomach cancer;protein:increased expression:stomach
associated with osteosarcoma
associated with lung non-small cell carcinoma
RGD PMID:20132185 PMID:26265454 PMID:24097870 RGD:126779607, RGD:11532507, RGD:126781716 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275
JBrowse link
G Ezr ezrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27137931 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G F2 coagulation factor II ISO associated with Carcinoma, Small cell;protein:increased expression:brain RGD PMID:22065054 RGD:6893520 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G Fadd Fas associated via death domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16450001 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fas Fas cell surface death receptor ISO
IEP
associated with Breast Neoplasms;protein:decreased expression:breast
associated with Mammary Neoplasms;protein:decreased expression:lung
RGD PMID:17352235 PMID:17918178 RGD:2290053, RGD:2290048 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand ISO associated with Breast Neoplasms;protein:decreased expression:breast RGD PMID:17352235 RGD:2290053 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fgf13 fibroblast growth factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr  X:58,107,499...58,630,932
Ensembl chr  X:58,107,505...58,613,431
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 IMP associated with prostate adenocarcinoma RGD PMID:23576558 RGD:13504748 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21975929 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Fn1 fibronectin 1 treatment ISO associated with stomach cancer; human cells in mouse model RGD PMID:27431311 RGD:152995400 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Fscn1 fascin actin-bundling protein 1 ISO associated with Pancreatic Neoplasms RGD PMID:15626919 RGD:2317788 NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940
JBrowse link
G Ftl1 ferritin light polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
JBrowse link
G Gab2 growth factor receptor bound protein 2-associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21996746 NCBI chr 7:96,730,958...96,958,158
Ensembl chr 7:96,730,793...96,958,153
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23996089 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17978847 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235
JBrowse link
G Gp1ba glycoprotein 1b, alpha polypeptide IMP associated with Melanoma, Experimental RGD PMID:19727118 RGD:10450866 NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862
JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25482527 NCBI chr 2:132,371,002...132,420,173
Ensembl chr 2:132,371,002...132,429,649
JBrowse link
G Gpi1 glucose-6-phosphate isomerase 1 IMP RGD PMID:20978190 RGD:11051956 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761
JBrowse link
G Gpx2 glutathione peroxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867582 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Habp2 hyaluronic acid binding protein 2 treatment ISO associated with Thyroid Neoplasms RGD PMID:22715430 RGD:11353856 NCBI chr19:56,275,541...56,309,252
Ensembl chr19:56,275,569...56,309,254
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 disease_progression ISO DNA:polymorphisms: : +4259T>G (human) RGD PMID:22472081 RGD:7245505 NCBI chr11:46,345,758...46,372,082
Ensembl chr11:46,345,762...46,372,082
JBrowse link
G Hdac3 histone deacetylase 3 IMP
ISO
associated with Anaphylaxis;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:34973135 PMID:24619412 RGD:9590165 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hgf hepatocyte growth factor ISO
IEP
associated with Pancreatic Neoplasms
CTD Direct Evidence: marker/mechanism
associated with Mammary Neoplasms, Experimental;
associated with Melanoma;
CTD
RGD
PMID:25971889 PMID:11893931 PMID:16459153 PMID:10688652 RGD:2317904, RGD:8548625, RGD:8548538 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hpse heparanase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22240343 NCBI chr 5:100,827,350...100,867,582
Ensembl chr 5:100,827,350...100,867,582
JBrowse link
G Hrh2 histamine receptor H2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6224980 NCBI chr13:54,345,990...54,390,201
Ensembl chr13:54,346,148...54,390,199
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Hspa1a heat shock protein 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26984758 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Ibsp integrin binding sialoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22407340 PMID:24980816 NCBI chr 5:104,447,153...104,459,338
Ensembl chr 5:104,447,037...104,459,335
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Pancreatic Neoplasms;protein:increased expression:serum
associated with Melanoma, Cutaneous Malignant
RGD PMID:12923961 PMID:10465581 RGD:2325163, RGD:8547593 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein ISO CTD Direct Evidence: therapeutic CTD PMID:24910342 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
JBrowse link
G Igf1 insulin-like growth factor 1 ISO associated with Pancreatic Neoplasms
CTD Direct Evidence: marker/mechanism
associated with Uveal Melanoma;protein:increased expression:serum:
CTD
RGD
PMID:18398872 PMID:19375852 PMID:23197685 RGD:2317643, RGD:8548834 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igf1r insulin-like growth factor I receptor ISO associated with Pancreatic Neoplasms RGD PMID:16575403 RGD:2317645 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Igf2 insulin-like growth factor 2 IEP associated with Arthritis, Experimental; protein:increased expression:lung, bone, serum: RGD PMID:21859454 RGD:5510000 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO associated with colorectal cancer;DNA:polymorphisms: RGD PMID:31320627 RGD:150540328 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926
JBrowse link
G Il10 interleukin 10 ISO RGD PMID:16035616 RGD:1598627 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with breast cancer;DNA:SNP:promoter:-137G>C (rs187238) (human)
associated with breast cancer;protein:increased expression:serum
CTD
RGD
PMID:12748951 PMID:11215816 PMID:19152241 PMID:12209760 RGD:4889862, RGD:8655899, RGD:8655866 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il2 interleukin 2 treatment ISO associated with melanoma;
associated with neuroblastoma.
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:17105418 PMID:8610104 PMID:9362156 PMID:8642346 RGD:8663438, RGD:14865005, RGD:14747043 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il6 interleukin 6 treatment ISO associated with stomach cancer, human cells in mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21937440 PMID:26101800 PMID:28186964 RGD:127229952 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Itga6 integrin alpha 6 ISO RGD PMID:13130099 RGD:1302259 NCBI chr 2:71,617,236...71,688,761
Ensembl chr 2:71,575,960...71,688,760
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23562787 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Itgb3 integrin beta 3 IEP
ISO
mRNA, protein:increased expression:lung
associated with renal cell carcinoma;DNA:missense mutation:cds:p.L33P (human)
RGD PMID:21107114 PMID:16831169 RGD:5037225, RGD:6907406 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Jak2 Janus kinase 2 treatment ISO associated with stomach cancer, human cells in mouse model RGD PMID:28186964 RGD:127229952 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Jup junction plakoglobin ISO associated with Ovarian Neoplasms RGD PMID:15619205 RGD:2301746 NCBI chr11:100,259,682...100,288,639
Ensembl chr11:100,259,784...100,288,589
JBrowse link
G Kdm6a lysine (K)-specific demethylase 6A disease_progression ISO associated with lung adenocarcinoma;protein:increased expression:brain (human) RGD PMID:33291558 RGD:150429741 NCBI chr  X:18,027,101...18,147,061
Ensembl chr  X:18,028,814...18,146,175
JBrowse link
G Kdr kinase insert domain protein receptor ISO associated with Carcinoma, Renal Cell RGD PMID:17465216 RGD:2301757 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kif2c kinesin family member 2C disease_progression ISO associated with colorectal cancer RGD PMID:18506187 RGD:27372891 NCBI chr 4:117,016,830...117,039,821
Ensembl chr 4:117,016,836...117,039,836
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor ISO associated with Ovarian Neoplasms RGD PMID:16283480 RGD:2298668 NCBI chr 1:133,249,625...133,257,460
Ensembl chr 1:133,237,565...133,257,460
Ensembl chr 1:133,237,565...133,257,460
JBrowse link
G Kmt2b lysine (K)-specific methyltransferase 2B ISO associated with lung adenocarcinoma RGD PMID:33291558 RGD:150429741 NCBI chr 7:30,268,280...30,288,371
Ensembl chr 7:30,268,283...30,288,151
JBrowse link
G Kmt2d lysine (K)-specific methyltransferase 2D disease_progression ISO associated with colorectal cancer;DNA:mutations:: RGD PMID:27875625 RGD:155582219 NCBI chr15:98,729,550...98,771,958
Ensembl chr15:98,729,550...98,769,085
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog treatment
disease_progression
ISO
IEP
CTD Direct Evidence: marker/mechanism
associated with stomach cancer; human cells in mouse model
associated with colorectal cancer; DNA:mutation:cds:
associated with colorectal cancer;DNA:mutations: :
associated with colorectal cancer;DNA:mutation: :
associated with Fibrosarcoma;mRNA,protein:decreased expression::
CTD
RGD
PMID:8635384 PMID:27431311 PMID:27264476 PMID:26210240 PMID:29032374 More... RGD:152995400, RGD:14398751, RGD:11086960, RGD:14398745, RGD:11570402 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Krt14 keratin 14 ISO mRNA:decreased expression:epithelial cell RGD PMID:9876218 RGD:1600180 NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374
JBrowse link
G Krt20 keratin 20 ISO associated with Colorectal Neoplasms RGD PMID:10931219 RGD:2317676 NCBI chr11:99,319,211...99,328,979
Ensembl chr11:99,319,229...99,328,976
JBrowse link
G L1cam L1 cell adhesion molecule treatment ISO associated with Pancreatic Neoplasms;
associated with Lung Neoplasms;
RGD PMID:22095073 PMID:22307136 RGD:11570404, RGD:11570503 NCBI chr  X:72,897,384...72,924,843
Ensembl chr  X:72,897,384...72,939,711
JBrowse link
G Lamc2 laminin, gamma 2 ISO associated with lung adenocarcinoma; RGD PMID:25591736 RGD:11075980 NCBI chr 1:152,998,502...153,062,193
Ensembl chr 1:152,998,502...153,062,193
JBrowse link
G Lcn2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24570342 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30453282 NCBI chr13:56,676,772...56,696,373
Ensembl chr13:56,690,277...56,696,315
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 ISO associated with prostate cancer
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:27811057 PMID:27067790 RGD:11531513 NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25882088 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Llgl2 LLGL2 scribble cell polarity complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr11:115,714,855...115,746,606
Ensembl chr11:115,714,875...115,746,606
JBrowse link
G Ly96 lymphocyte antigen 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22180778 NCBI chr 1:16,758,680...16,779,829
Ensembl chr 1:16,758,275...16,779,835
JBrowse link
G Macc1 metastasis associated in colon cancer 1 treatment ISO associated with stomach cancer; human cells in mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:36008464 PMID:27431311 RGD:152995400 NCBI chr12:119,354,133...119,430,669
Ensembl chr12:119,278,005...119,433,722
JBrowse link
G Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:24244343 PMID:26735578 PMID:30349115 NCBI chr19:5,845,718...5,852,700
Ensembl chr19:5,845,717...5,852,706
JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 disease_progression ISO associated with oral squamous cell carcinoma;mRNA, protein:increased expression:lymph node (human) RGD PMID:22165133 RGD:150429749 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO
IDA
CTD Direct Evidence: marker/mechanism
associated with prostate adenocarcinoma
CTD
RGD
PMID:22580338 PMID:22139534 RGD:13504820 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22580338 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: therapeutic
associated with Colorectal Neoplasms
CTD
RGD
PMID:21779479 PMID:25205654 RGD:13217416 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Med28 mediator complex subunit 28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21942447 NCBI chr 5:45,677,571...45,686,626
Ensembl chr 5:45,677,571...45,686,618
JBrowse link
G Met met proto-oncogene disease_progression ISO associated with Squamous Cell Carcinoma of the Tongue;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20080979 PMID:21225626 PMID:22704061 RGD:8548616 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mir100 microRNA 100 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 9:41,442,721...41,442,800
Ensembl chr 9:41,442,721...41,442,800
JBrowse link
G Mir106a microRNA 106a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:51,831,380...51,831,444
Ensembl chr  X:51,831,380...51,831,444
JBrowse link
G Mir125a microRNA 125a ISO CTD Direct Evidence: marker/mechanism
associated with stomach cancer;
CTD
RGD
PMID:19487542 PMID:30117667 RGD:21403678 NCBI chr17:18,051,074...18,051,141
Ensembl chr17:18,051,074...18,051,141
JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 2:84,571,459...84,571,522
Ensembl chr 2:84,571,459...84,571,522
JBrowse link
G Mir130b microRNA 130b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr16:16,941,925...16,942,006
Ensembl chr16:16,941,925...16,942,006
JBrowse link
G Mir136 microRNA 136 ameliorates ISO associated with stomach cancer;human cells in mouse model RGD PMID:28656883 RGD:153344628 NCBI chr12:109,561,761...109,561,822
Ensembl chr12:109,561,761...109,561,822
JBrowse link
G Mir148b microRNA 148b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr15:103,193,552...103,193,648
Ensembl chr15:103,193,552...103,193,648
JBrowse link
G Mir152 microRNA 152 ISO associated with Castration-Resistant Prostatic Neoplasms RGD PMID:23574937 RGD:19165145 NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291
JBrowse link
G Mir155 microRNA 155 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19487542 PMID:27692344 PMID:27856635 RGD:21079446 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 8:84,905,502...84,905,590
Ensembl chr 8:84,905,502...84,905,590
JBrowse link
G Mir181d microRNA 181d ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 8:84,905,345...84,905,416
Ensembl chr 8:84,905,345...84,905,416
JBrowse link
G Mir18b microRNA 18b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:51,831,208...51,831,290
Ensembl chr  X:51,831,208...51,831,290
JBrowse link
G Mir193a microRNA 193a exacerbates ISO associated with colorectal cancer; miRNA:decreased expression:colorectum (human)
associated with lung non-small cell carcinoma; human cells in mouse model
RGD PMID:25232258 PMID:30685413 PMID:24469061 RGD:153344566, RGD:153344599, RGD:153344592 NCBI chr11:79,602,795...79,602,860
Ensembl chr11:79,602,795...79,602,860
JBrowse link
G Mir19a microRNA 19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr14:115,281,432...115,281,513
Ensembl chr14:115,281,432...115,281,513
JBrowse link
G Mir205 microRNA 205 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 1:193,189,771...193,189,838
Ensembl chr 1:193,189,771...193,189,838
JBrowse link
G Mir20a microRNA 20a ISO associated with colorectal cancer RGD PMID:27286257 RGD:25823157 NCBI chr14:115,281,589...115,281,695
Ensembl chr14:115,281,589...115,281,695
JBrowse link
G Mir20b microRNA 20b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:51,830,990...51,831,069
Ensembl chr  X:51,830,990...51,831,069
JBrowse link
G Mir21a microRNA 21a treatment
ameliorates
ISO associated with prostate carcinoma; human cells in mouse model
CTD Direct Evidence: marker/mechanism
human cells in mouse model;associated with breast cancer
CTD
RGD
PMID:26101800 PMID:32736696 PMID:18270520 RGD:152998873, RGD:152998897 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Mir221 microRNA 221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:19,012,533...19,012,627
Ensembl chr  X:19,012,533...19,012,627
JBrowse link
G Mir222 microRNA 222 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:19,013,132...19,013,210
Ensembl chr  X:19,013,132...19,013,210
JBrowse link
G Mir224 microRNA 224 ISO CTD Direct Evidence: marker/mechanism
associated with colorectal cancer; mRNA:increased expression:colorectal mucosa:
CTD
RGD
PMID:19487542 PMID:25919696 RGD:14398749 NCBI chr  X:71,304,637...71,304,718
Ensembl chr  X:71,304,637...71,304,718
JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420
JBrowse link
G Mir30e microRNA 30e ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 4:120,629,803...120,629,894
Ensembl chr 4:120,629,803...120,629,894
JBrowse link
G Mir31 microRNA 31 disease_progression
treatment
ISO CTD Direct Evidence: marker/mechanism
associated with colorectal cancer;RNA:increased expression:colorectum (human)
associated with stomach cancer;human cells in mouse model
CTD
RGD
PMID:19487542 PMID:26497852 PMID:27174918 PMID:30108104 RGD:153297806, RGD:153297811, RGD:153297776 NCBI chr 4:88,828,794...88,828,899
Ensembl chr 4:88,828,794...88,828,899
JBrowse link
G Mir335 microRNA 335 ISO lung metastasis RGD PMID:21822301 RGD:14394425 NCBI chr 6:30,741,298...30,741,395
Ensembl chr 6:30,741,298...30,741,395
JBrowse link
G Mir342 microRNA 342 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr12:108,624,879...108,624,977
Ensembl chr12:108,624,879...108,624,977
JBrowse link
G Mir346 microRNA 346 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27501413 PMID:27777383 NCBI chr14:34,616,566...34,616,663
Ensembl chr14:34,616,566...34,616,663
JBrowse link
G Mir34b microRNA 34b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 9:51,014,862...51,014,945
Ensembl chr 9:51,014,862...51,014,945
JBrowse link
G Mir34c microRNA 34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 9:51,014,334...51,014,410
Ensembl chr 9:51,014,334...51,014,410
JBrowse link
G Mir370 microRNA 370 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr12:109,584,692...109,584,770
Ensembl chr12:109,584,692...109,584,770
JBrowse link
G Mir494 microRNA 494 ISO associated with osteosarcoma; RNA:decreased expression:bone, serum RGD PMID:30314946 PMID:35117781 RGD:156420141, RGD:156430319 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836
JBrowse link
G Mir503 microRNA 503 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:52,142,861...52,142,931
Ensembl chr  X:52,142,861...52,142,931
JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:7,114,641...7,114,736
Ensembl chr  X:7,114,641...7,114,736
JBrowse link
G Mir96 microRNA 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550
JBrowse link
G Mir99a microRNA 99a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr16:77,395,824...77,395,888
Ensembl chr16:77,395,824...77,395,888
JBrowse link
G Mir99b microRNA 99b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr17:18,050,450...18,050,519
Ensembl chr17:18,050,450...18,050,519
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 ISO associated with Pancreatic Neoplasms RGD PMID:20388395 RGD:2317702 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mlh1 mutL homolog 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17717427 NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22022614 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO associated with Carcinoma, Renal Cell;mRNA, protein:increased expression:bone RGD PMID:18709334 RGD:2306080 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:12538496 PMID:19487542 PMID:22580338 PMID:23548910 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 disease_progression ISO associated with Gallbladder Neoplasms; protein:increased expression:gallbladder
associated with pancreatic cancer; protein:increased expression, increased activity:pancreas
CTD Direct Evidence: marker/mechanism
associated with Mammary Neoplasms, Animal;protein:increased expression:brain
RGD
CTD
PMID:12173379 PMID:16475674 PMID:18398872 PMID:21209944 PMID:22321834 More... RGD:2325749, RGD:2325743, RGD:8547884, RGD:2325749 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp24 matrix metallopeptidase 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869830 NCBI chr 2:155,617,262...155,660,286
Ensembl chr 2:155,617,262...155,660,286
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO associated with Mammary Neoplasms, Animal;protein:increased expression:brain RGD PMID:16158251 RGD:8547884 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 severity
disease_progression
ISO
IMP
IEP
associated with pancreatic cancer; protein:increased expression, increased activity:pancreas
CTD Direct Evidence: marker/mechanism
associated with osteosarcoma;protein:increased expression:bone (human)
associated with skin melanoma;DNA:missense mutation:cds:p.Q279R (human)
associated with Mammary Neoplasms, Animal;protein:increased expression:brain
associated with Melanoma
associated with Mammary Neoplasms, Animal; associated with Arthritis, Experimental
associated with carcinoma, pancreatic ductal; protein:increased expression:pancreas
CTD
RGD
PMID:15659795 PMID:16475674 PMID:18930813 PMID:21209944 PMID:21942447 More... RGD:152023746, RGD:2325749, RGD:8547928, RGD:8547886, RGD:8547884, RGD:8547878, RGD:8547861, RGD:5510000, RGD:2325855 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Msh2 mutS homolog 2 ISO associated with Breast Neoplasms RGD PMID:17390069 RGD:2293506 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
JBrowse link
G Mst1 macrophage stimulating 1 (hepatocyte growth factor-like) ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr 9:107,957,607...107,962,226
Ensembl chr 9:107,957,635...107,962,202
JBrowse link
G Mtdh metadherin ISO CTD Direct Evidence: therapeutic CTD PMID:19111877 NCBI chr15:34,082,613...34,143,683
Ensembl chr15:34,082,840...34,145,770
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17704422 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO associated with Pancreatic Neoplasms RGD PMID:23149918 RGD:10040959 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Muc1 mucin 1, transmembrane disease_progression ISO associated with Pancreatic Neoplasms
associated with Carcinoma, Renal Cell;
RGD PMID:16707592 PMID:10390012 PMID:12941828 RGD:2324648, RGD:7245968, RGD:2324652 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc4 mucin 4 ISO associated with Melanoma RGD PMID:10918186 RGD:2303746 NCBI chr16:32,555,089...32,602,786
Ensembl chr16:32,555,015...32,602,754
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric ISO associated with chloangiocarcinoma;protein:increased expression:bile duct RGD PMID:16124042 RGD:2324987 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Muc6 mucin 6, gastric disease_progression ISO associated with cholangiocarcinoma RGD PMID:18410610 RGD:2325159 NCBI chr 7:141,212,404...141,241,659
Ensembl chr 7:141,213,373...141,241,641
JBrowse link
G Myc myelocytomatosis oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:22321834 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Mylk myosin, light polypeptide kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12970723 PMID:18710790 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
JBrowse link
G Nagk N-acetylglucosamine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 6:83,770,810...83,779,538
Ensembl chr 6:83,771,964...83,781,000
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21080969 NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
JBrowse link
G Ndc80 NDC80 kinetochore complex component disease_progression ISO associated with melanoma RGD PMID:31173190 RGD:40822820 NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852
JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15867226 PMID:22972152 NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29321541 NCBI chr 7:19,450,569...19,483,498
Ensembl chr 7:19,450,569...19,484,408
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32682831 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 ISO associated with prostate cancer RGD PMID:17974971 RGD:13506764 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha ISO associated with prostate cancer;protein:increased serine phosphorylation RGD PMID:23093296 RGD:13506767 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO associated with Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15928304 PMID:7622307 RGD:2299069 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 resistance ISO RGD PMID:8621239 RGD:2299081 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085
JBrowse link
G Nos2 nitric oxide synthase 2, inducible disease_progression IMP
ISO
associated with Carcinoma, Pancreatic Ductal
associated with Carcinoma, Pancreatic Ductal; protein:increased expression:pancreas
associated with Gallbladder Neoplasms: protein:increased expression:gallbladder
RGD PMID:12660813 PMID:15222037 PMID:14991947 RGD:2325254, RGD:2325242, RGD:2325250 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell susceptibility ISO protein:increased expression:blood vessel endothelial cell
associated with Prostatic Neoplasms;DNA:polymorphism
associated with Breast Neoplasms;DNA:polymorphism:promoter:-786T>C (human)
RGD PMID:14672505 PMID:12445681 PMID:14623178 RGD:2292080, RGD:2292087, RGD:2292081 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nppa natriuretic peptide type A ISO CTD Direct Evidence: therapeutic CTD PMID:18717826 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nsun6 NOL1/NOP2/Sun domain family member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr 2:14,995,255...15,059,683
Ensembl chr 2:14,999,942...15,059,880
JBrowse link
G Ogn osteoglycin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr13:49,761,491...49,777,977
Ensembl chr13:49,761,522...49,777,977
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 ISO associated with breast cancer RGD PMID:27340107 RGD:40902824 NCBI chr16:91,016,745...91,025,567
Ensembl chr16:91,022,345...91,025,565
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 treatment ISO associated with stomach cancer; human cells in mouse model RGD PMID:27431311 RGD:152995400 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519
JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:21937440 NCBI chr11:4,186,831...4,191,027
Ensembl chr11:4,186,420...4,191,026
JBrowse link
G Pcna proliferating cell nuclear antigen ISO associated with Seminoma RGD PMID:9143022 RGD:2315011 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:12972520 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO associated with Breast Neoplasms;mRNA, protein:increased expression:breast RGD PMID:16596190 RGD:2292179 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide ISO associated with Carcinoma, Renal Cell
mRNA,protein:increased expression: :
RGD PMID:15994946 PMID:14593398 RGD:2292198, RGD:13703041 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO associated with Prostatic Neoplasms;protein:decreased expression: RGD PMID:12813171 RGD:2302862 NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21986133 NCBI chr 1:132,973,410...133,036,429
Ensembl chr 1:132,973,405...133,036,425
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha treatment ISO CTD Direct Evidence: marker/mechanism
associated with colorectal cancer;DNA:mutations::
CTD
RGD
PMID:29106415 PMID:23302486 RGD:14402409 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 ISO associated with Adenocarcinoma, Colon RGD PMID:24837077 RGD:13432045 NCBI chr 4:116,078,593...116,160,253
Ensembl chr 4:116,078,815...116,160,253
Ensembl chr 4:116,078,815...116,160,253
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16475674 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plaur plasminogen activator, urokinase receptor IMP
ISO
associated with Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15659795 PMID:22577342 RGD:6483788 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 ameliorates ISO associated with lung non-small cell carcinoma RGD PMID:29072684 RGD:151665822 NCBI chr 9:92,421,828...92,490,481
Ensembl chr 9:92,424,276...92,490,481
JBrowse link
G Pml promyelocytic leukemia ISO CTD Direct Evidence: marker/mechanism CTD PMID:29335545 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Pms2 PMS1 homolog2, mismatch repair system component ISO CTD Direct Evidence: marker/mechanism CTD PMID:17717427 NCBI chr 5:143,846,379...143,922,538
Ensembl chr 5:143,846,782...143,870,786
Ensembl chr 5:143,846,782...143,870,786
JBrowse link
G Ppia peptidylprolyl isomerase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21956400 NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817
JBrowse link
G Prnp prion protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17387271 NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349
JBrowse link
G Prox1 prospero homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17415710 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911
JBrowse link
G Prss8 serine protease 8 (prostasin) ISO associated with Prostatic Neoplasms;mRNA:decreased expression:prostate gland, bone RGD PMID:12518323 RGD:2292484 NCBI chr 7:127,524,889...127,529,266
Ensembl chr 7:127,524,888...127,529,276
JBrowse link
G Ptch1 patched 1 ISO associated with colorectal cancer RGD PMID:20230186 RGD:150523835 NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412
JBrowse link
G Pten phosphatase and tensin homolog IAGP
ISO
associated with Mammary Neoplasms, Experimental
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:10978354 PMID:18381417 RGD:2292496 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase exacerbates ISO associated with colorectal cancer; protein:increased expression:colorectum (human) RGD PMID:22109564 RGD:151347833 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO
IMP
associated with Breast Neoplasms
CTD Direct Evidence: marker/mechanism
associated with osteosarcoma;
associated with breast neoplasm;
associated with lung neoplasm
associated with Mammary Neoplasms, Experimental
CTD
RGD
PMID:16489006 PMID:18509974 PMID:18663571 PMID:18797196 PMID:19421193 More... RGD:2300119, RGD:5135500, RGD:5135498, RGD:5135282, RGD:2300249 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 IMP
ISO
associated with Mammary Neoplasms, Experimental RGD PMID:16547501 PMID:15930288 RGD:2292557, RGD:2292560 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Pxn paxillin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18492274 NCBI chr 5:115,630,035...115,694,046
Ensembl chr 5:115,644,735...115,694,046
JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18506888 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility ISO associated with colorectal cancer; DNA:SNP:3'utr: (rs7963551) (human) RGD PMID:29245274 RGD:151361161 NCBI chr 6:119,878,781...119,899,789
Ensembl chr 6:119,879,659...119,899,789
JBrowse link
G Ramp2 receptor (calcitonin) activity modifying protein 2 IMP RGD PMID:31754214 RGD:152985691 NCBI chr11:101,137,160...101,139,076
Ensembl chr11:101,136,854...101,150,372
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27137931 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs ISO CTD Direct Evidence: marker/mechanism CTD PMID:17233834 NCBI chr 4:43,875,521...43,944,806
Ensembl chr 4:43,875,530...43,944,806
JBrowse link
G Rhoa ras homolog family member A ISO associated with Ovarian Neoplasms RGD PMID:12808121 RGD:2298873 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Rhoc ras homolog family member C ISO associated with Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18230616 PMID:12808121 RGD:2298873 NCBI chr 3:104,696,350...104,701,775
Ensembl chr 3:104,695,691...104,701,775
JBrowse link
G Rit1 Ras-like without CAAX 1 ameliorates ISO associated with esophagus squamous cell carcinoma; human cells in mouse model RGD PMID:30348939 RGD:152999018 NCBI chr 3:88,624,154...88,638,354
Ensembl chr 3:88,624,145...88,638,356
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr 4:99,952,988...100,302,003
Ensembl chr 4:99,952,988...100,301,962
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase polypeptide 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21488662 NCBI chr  X:158,038,652...158,151,240
Ensembl chr  X:157,993,303...158,151,240
JBrowse link
G Rxra retinoid X receptor alpha ISO associated with Prostatic Neoplasms RGD PMID:15318950 RGD:1643115 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G S100a4 S100 calcium binding protein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21636539 PMID:21685359 PMID:36008464 NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352
JBrowse link
G Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A IEP associated with Pancreatic Neoplasms;mRNA:increased expression:pancreas (mouse) RGD PMID:18218118 RGD:2324959 NCBI chr12:103,819,554...103,829,878
Ensembl chr12:103,819,848...103,829,821
JBrowse link
G Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19514085 NCBI chr 1:106,788,905...106,811,078
Ensembl chr 1:106,788,903...106,811,078
JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 treatment ISO
IMP
associated with Adenocarcinoma, Colon
associated with Melanoma
RGD PMID:16440418 PMID:16440418 RGD:1599327, RGD:1599327 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433
JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 ISO associated with Prostatic Neoplasms RGD PMID:15313905 RGD:2312355 NCBI chr11:75,300,855...75,313,449
Ensembl chr11:75,300,595...75,313,527
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27793039 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Six1 sine oculis-related homeobox 1 ISO human gene in a mouse model RGD PMID:23435380 RGD:11561950 NCBI chr12:73,088,601...73,093,486
Ensembl chr12:73,086,789...73,100,661
JBrowse link
G Slc39a4 solute carrier family 39 (zinc transporter), member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20957146 NCBI chr15:76,496,583...76,501,579
Ensembl chr15:76,496,583...76,501,584
JBrowse link
G Slc39a6 solute carrier family 39 (metal ion transporter), member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12839489 NCBI chr18:24,712,938...24,736,874
Ensembl chr18:24,712,938...24,736,874
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 ISO RGD PMID:19018776 RGD:151361278 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19015640 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 ISO RGD PMID:19018776 RGD:151361278 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 ISO associated with Colonic Neoplasms;protein:decreased expression:liver RGD PMID:16895976 RGD:2302565 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Smad4 SMAD family member 4 disease_progression ISO associated with colorectal carcinoma;DNA:mutation:cds: RGD PMID:10340381 RGD:21066333 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
JBrowse link
G Smo smoothened, frizzled class receptor ISO associated with colon cancer RGD PMID:23098507 RGD:150340555 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364
JBrowse link
G Snai1 snail family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22580338 PMID:23219715 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734
JBrowse link
G Snai2 snail family zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22580338 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
JBrowse link
G Sncg synuclein, gamma ISO protein:increased expression:breast
DNA:hypomethylation: :
RGD PMID:16821081 PMID:16140929 RGD:6478795, RGD:6478797 NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:12538496 PMID:18930813 PMID:19487542 PMID:22580338 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sox30 SRY (sex determining region Y)-box 30 ISO associated with lung non-small cell carcinoma;mRNA, protein:decreased expression: : RGD PMID:29739711 RGD:151660333 NCBI chr11:45,869,873...45,908,824
Ensembl chr11:45,871,137...45,908,821
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32682831 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Sp1 trans-acting transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12538496 PMID:35072892 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
JBrowse link
G Spa17 sperm autoantigenic protein 17 ISO associated with ovarian carcinoma;proetin:increased expression:epithelium: RGD PMID:19744347 RGD:27226802 NCBI chr 9:37,514,590...37,525,018
Ensembl chr 9:37,514,586...37,525,018
JBrowse link
G Spp1 secreted phosphoprotein 1 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22407340 PMID:16474180 RGD:1581330 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Src Rous sarcoma oncogene IDA
ISO
associated with colorectal carcinoma;protein:increased activity:colorectum: RGD PMID:15486073 PMID:7687314 RGD:1581401, RGD:150521537 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30394316 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Srsf1 serine and arginine-rich splicing factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr11:87,937,325...87,944,583
Ensembl chr11:87,938,199...87,944,581
JBrowse link
G Srsf2 serine and arginine-rich splicing factor 2 severity ISO associated with hepatocellular carcinoma RGD PMID:29278882 RGD:150429692 NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920
JBrowse link
G Srsf5 serine and arginine-rich splicing factor 5 ISO associated with Ovarian Neoplasms;mRNA:increased expression:epithelium of female gonad (human) RGD PMID:23748175 RGD:11039469 NCBI chr12:80,992,308...80,997,277
Ensembl chr12:80,992,278...80,997,281
JBrowse link
G Srsf6 serine and arginine-rich splicing factor 6 ISO associated with Ovarian Neoplasms;mRNA:increased expression:epithelium of female gonad (human) RGD PMID:23748175 RGD:11039469 NCBI chr 2:162,773,428...162,779,041
Ensembl chr 2:162,773,448...162,779,041
JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) ISO associated with Prostatic Neoplasms
associated with Breast Neoplasms
RGD PMID:18813126 PMID:17456594 RGD:2315088, RGD:2315092 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29147627 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO associated with Carcinoma, Renal Cell;protein:increased phosphorylation
CTD Direct Evidence: marker/mechanism
associated with Melanoma
associated with Prostatic Neoplasms;protein:decreased activity
CTD
RGD
PMID:21937440 PMID:23382965 PMID:26101800 PMID:12131365 PMID:16540670 More... RGD:2291917, RGD:8694303, RGD:2291915 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stat5a signal transducer and activator of transcription 5A disease_progression ISO DNA:CNV: :prostate (human) RGD PMID:23660011 RGD:151667415 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
JBrowse link
G Stim1 stromal interaction molecule 1 ameliorates
treatment
exacerbates
ISO human cells in mouse model;associated with lung cancer
associated with stomach cancer; human cells in mouse model
associated with hepatocellular carcinoma;protein:decreased expression:liver (human)
associated with nasopharynx carcinoma; human cells in mouse model
RGD PMID:28713917 PMID:27431311 PMID:32483465 PMID:32165272 RGD:152995357, RGD:152995400, RGD:152995387, RGD:152995361 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526
JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 ISO associated with Colonic Neoplasms;protein:increased expression:liver RGD PMID:16895976 RGD:2302565 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453
JBrowse link
G Tbcb tubulin folding cofactor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 7:29,923,554...29,931,622
Ensembl chr 7:29,923,556...29,931,697
JBrowse link
G Tcf3 transcription factor 3 disease_progression ISO associated with colon cancer RGD PMID:26212009 RGD:11533019 NCBI chr10:80,245,375...80,269,814
Ensembl chr10:80,245,348...80,269,481
JBrowse link
G Tcl1b1 T cell leukemia/lymphoma 1B, 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228224 NCBI chr12:105,125,963...105,132,884
Ensembl chr12:105,125,949...105,132,884
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO associated with colorectal cancer; protein:decreased expression:colorectum (human) RGD PMID:33552282 RGD:150429609 NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
associated with stomach carcinoma;DNA:hypermethylation
CTD
RGD
PMID:17372906 PMID:25009298 RGD:150527841 NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23146760 PMID:23992306 PMID:26896736 PMID:31381904 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I ISO associated with Mammary Neoplasms, Experimental RGD PMID:12808151 RGD:737735 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II ISO associated with Mammary Neoplasms, Experimental
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:16489006 PMID:12808151 RGD:737735 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29746904 NCBI chr17:71,151,200...71,160,527
Ensembl chr17:71,151,200...71,160,541
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 ISO associated with Breast Neoplasms;protein:increased expression:plasma RGD PMID:17407159 RGD:2290346 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 ISO associated with Breast Neoplasms RGD PMID:17505812 RGD:2290394 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22180778 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnc tenascin C ISO associated with Carcinoma, Renal Cell;protein:increased expression:lung RGD PMID:16928692 RGD:4889612 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8032535 PMID:23431386 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21969086 NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240
JBrowse link
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator ISO associated with Prostatic Neoplasms;protein:increased expression:bone, lymph node RGD PMID:16752412 RGD:2302322 NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) ISO associated with Breast Neoplasms;protein:increased expression:serum RGD PMID:23167338 RGD:7205479 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:21209944 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 8:72,889,132...72,906,986
Ensembl chr 8:72,884,018...72,906,986
JBrowse link
G Trp53 transformation related protein 53 ISO
EXP
CTD Direct Evidence: marker/mechanism
associated with Sarcoma;
CTD
RGD
PMID:17949449 PMID:22009531 PMID:23873029 PMID:27137931 PMID:15118671 More... RGD:1331525, RGD:11075090 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp63 transformation related protein 63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15875781 NCBI chr16:25,502,513...25,710,842
Ensembl chr16:25,502,513...25,710,852
JBrowse link
G Ttr transthyretin treatment ISO associated with colorectal adenocarcinoma;protein:decreased expression:colorectum (human)
associated with colorectal cancer
associated with oral squamous cell carcinoma;protein:decreased expression:blood serum, saliva (human)
RGD PMID:33739034 PMID:28730771 PMID:20957082 RGD:151660505, RGD:151665163, RGD:151665158 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378
JBrowse link
G Twist1 twist basic helix-loop-helix transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19806464 NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828
JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30396169 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txndc5 thioredoxin domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr13:38,684,242...38,712,800
Ensembl chr13:38,684,055...38,712,800
JBrowse link
G Tymp thymidine phosphorylase ISO associated with Breast Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11103787 PMID:18441329 RGD:2293714 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242
JBrowse link
G Tyms thymidylate synthase disease_progression ISO associated with Gastrointestinal Neoplasms;DNA:SNPs: : RGD PMID:25677447 RGD:11081002 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
JBrowse link
G Tyr tyrosinase no_association ISO associated with melanoma; RGD PMID:11092039 RGD:8694395 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
G Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr14:101,891,387...101,933,561
Ensembl chr14:101,891,403...101,933,561
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO associated with Pancreatic Neoplasms;protein:increased expression:serum RGD PMID:12923961 RGD:2325163 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor ISO associated with breast cancer;DNA:SNP:intron: (rs1544410) (human) RGD PMID:9613456 RGD:8158057 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with Carcinoma, Renal Cell
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15659795 PMID:18930813 PMID:20158913 PMID:19064974 RGD:2315468 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vim vimentin treatment ISO CTD Direct Evidence: marker/mechanism
associated with stomach cancer; human cells in mouse model
CTD
RGD
PMID:17085005 PMID:27431311 RGD:152995400 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Vip vasoactive intestinal polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19189304 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617
JBrowse link
G Wfdc18 WAP four-disulfide core domain 18 ISO associated with Mammary Neoplasms, Experimental;mRNA:increased expression RGD PMID:3136918 RGD:632771 NCBI chr11:83,599,830...83,602,186
Ensembl chr11:83,599,841...83,602,174
JBrowse link
G Xpc xeroderma pigmentosum, complementation group C ISO CTD Direct Evidence: marker/mechanism CTD PMID:27777383 NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870
JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 susceptibility ISO associated with Neoplasms, Germ Cell and Embryonal;DNA:polymorphism: :p.R399Q RGD PMID:16596238 RGD:2302576 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865
JBrowse link
G Yap1 yes-associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr11:75,620,121...75,656,667
Ensembl chr11:75,623,695...75,656,671
JBrowse link
G Zfhx3 zinc finger homeobox 3 exacerbates ISO brain metastasis associated with lung adenocarcinoma;DNA:mutations:multiple (human) RGD PMID:33479213 RGD:151361170 NCBI chr 8:109,005,975...109,688,272
Ensembl chr 8:108,669,276...109,688,262
JBrowse link
G Zfp382 zinc finger protein 382 disease_progression ISO associated with stomach carcinoma;DNA:hypermethylation RGD PMID:25009298 RGD:150527841 NCBI chr 7:29,821,255...29,840,180
Ensembl chr 7:29,821,367...29,834,375
JBrowse link
Bone Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase ISO associated with Prostatic Neoplasms; RGD PMID:14669797 RGD:1578303 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179
JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 ISO associated with Breast Neoplasms; human gene in a mouse model RGD PMID:22875853 RGD:11252149 NCBI chr11:85,948,957...86,092,041
Ensembl chr11:85,948,964...86,092,019
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO associated with hepatocellular carcinoma;protein:increased expression:liver (human) RGD PMID:19508713 RGD:152023653 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO associated with Breast Neoplasms;mRNA:increased expression:bone element (human) RGD PMID:23861746 RGD:13204736 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057
JBrowse link
G Mir34a microRNA 34a susceptibility ISO associated with hepatocellular carcinoma;miRNA:decreased expression:serum, bone RGD PMID:27893432 RGD:14694837 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012
JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO associated with Carcinoma, Renal Cell; mRNA, protein:increased expression:bone (human) RGD PMID:18709334 RGD:2306080 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Pdgfd platelet-derived growth factor, D polypeptide ISO associated with prostate carcinoma RGD PMID:22158043 RGD:13506772 NCBI chr 9:6,168,377...6,534,284
Ensembl chr 9:6,168,584...6,378,850
JBrowse link
Circulating Neoplastic Cells term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29044505 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
Liver Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEP associated with colorectal cancer;mRNA:increased expression:liver (mouse) RGD PMID:20380732 RGD:25671446 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Braf Braf transforming gene severity IAGP associated with colorectal cancer;DNA:mutation:cds:
associated with colorectal cancer;DNA:mutations:multiple
associated with skin melanoma;DNA:missense mutations:cds:
associated with colorectal cancer;DNA:missense mutations:cds:pV599E,p.V600E (human)
associated with colorectal cancer;DNA:missense mutation:cds:p.V600E (human)
RGD PMID:27737491 PMID:26775732 PMID:28787433 PMID:22331825 PMID:23010994 RGD:18337264, RGD:11554843, RGD:14696791, RGD:18337265, RGD:15039394 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 disease_progression ISO associated with colorectal cancer RGD PMID:27058904 RGD:14995463 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment IMP associated with Animal Mammary Neoplasms; RGD PMID:15692764 RGD:14995455 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccnd2 cyclin D2 ISO associated with colorectal cancer;protein:increased expression:colorectum RGD PMID:19508551 RGD:151665111 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
JBrowse link
G Ccng1 cyclin G1 treatment ISO human cells in mouse model RGD PMID:10910035 RGD:151356987 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Cd44 CD44 antigen ISO associated with Breast Neoplasm;protein:increased expression:liver RGD PMID:17991717 RGD:2289349 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates ISO associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr 6:125,073,144...125,107,554
Ensembl chr 6:125,072,944...125,107,554
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment IDA associated with colon carcinoma; RGD PMID:30381616 RGD:27095891 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ameliorates ISO associated with colorectal cancer; human cells in mouse model RGD PMID:30789971 RGD:151893289 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 ISO associated with colorectal cancer; human colon adenocarcinoma cells in a mouse model RGD PMID:29679563 RGD:26884358 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ameliorates ISO associated with colorectal cancer; human cells in mouse model
human cells in mouse model; associated with colorectal cancer
RGD PMID:30789971 PMID:29436696 RGD:151893289, RGD:152023643 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Daxx Fas death domain-associated protein exacerbates ISO associated with colon cancer; mRNA:decreased expression:liver (human)
associated with pancreatic endocrine carcinoma;DNA:mutations:CDS:multiple (human)
associated with neuroendocrine tumor;DNA:mutations:CDS:multiple (human)
RGD PMID:31942198 PMID:30339629 PMID:30342802 RGD:152025194, RGD:152025203, RGD:152025199 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 treatment IMP
IEP
ISO
mRNA:increased expression:liver (mouse)
human cells in mouse model; nilotinib
RGD PMID:33110221 PMID:30666650 PMID:29438985 RGD:151347537, RGD:151347840, RGD:151347685 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Ddr2 discoidin domain receptor family, member 2 ameliorates IMP
ISO
associated with colon carcinoma
associated with melanoma;
RGD PMID:22071959 PMID:21701781 RGD:150429701, RGD:150429713 NCBI chr 1:169,799,874...169,938,525
Ensembl chr 1:169,799,876...169,938,331
JBrowse link
G Dock6 dedicator of cytokinesis 6 ameliorates ISO associated with stomach cancer; RGD PMID:29587866 RGD:155791564 NCBI chr 9:21,711,476...21,764,006
Ensembl chr 9:21,711,156...21,763,931
JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 disease_progression ISO associated with colorectal cancer; RGD PMID:28846828 RGD:21408566 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 ISO associated with colorectal cancer;mRNA:increased expression:colorectal mucosa: RGD PMID:19082464 RGD:25330357 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fosl2 fos-like antigen 2 ISO human cells in mouse model RGD PMID:30114390 RGD:153344554 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
JBrowse link
G Gpc3 glypican 3 ISO protein:increased expression:blood serum (human) RGD PMID:28801286 RGD:243065135 NCBI chr  X:51,361,303...51,702,851
Ensembl chr  X:51,361,303...51,702,827
JBrowse link
G Hmbs hydroxymethylbilane synthase ISO associated with colon adenocarcinoma;protein:decreased activity:liver(rat) RGD PMID:1386052 RGD:25440496 NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525
JBrowse link
G Il2 interleukin 2 treatment ISO associated with Colorectal Neoplasms, Carcinoma, Hepatocellular;
associated with colon carcinoma
RGD PMID:11591892 PMID:9354462 RGD:8663446, RGD:14928215 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Iqsec1 IQ motif and Sec7 domain 1 ISO human cells in mouse model RGD PMID:22662237 RGD:153344589 NCBI chr 6:90,636,578...90,965,766
Ensembl chr 6:90,633,070...90,965,667
JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 ISO associated with colon cancer;protein:increased expression:colon (human) RGD PMID:24533778 RGD:155259116 NCBI chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897
JBrowse link
G Mir141 microRNA 141 ISO associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr 6:124,694,877...124,694,948
Ensembl chr 6:124,694,877...124,694,948
JBrowse link
G Mir148b microRNA 148b exacerbates ISO associated with stomach cancer; RGD PMID:29587866 RGD:155791564 NCBI chr15:103,193,552...103,193,648
Ensembl chr15:103,193,552...103,193,648
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:26885061 RGD:21079444 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
JBrowse link
G Mir200b microRNA 200b ISO associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr 4:156,140,138...156,140,207
Ensembl chr 4:156,140,138...156,140,207
JBrowse link
G Mir200c microRNA 200c ISO associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr 6:124,695,285...124,695,353
Ensembl chr 6:124,695,285...124,695,353
JBrowse link
G Mir223 microRNA 223 disease_progression ISO associated with colorectal cancer; RGD PMID:28846828 RGD:21408566 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532
JBrowse link
G Mir494 microRNA 494 exacerbates ISO associated with pancreatic ductal adenocarcinoma; RGD PMID:24859161 RGD:156430321 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836
JBrowse link
G Mpl myeloproliferative leukemia virus oncogene severity
exacerbates
IMP
ISO
associated with pancreatic ductal adenocarcinoma; human cells in mouse model
associated with colorectal carcinoma;protein:increased expression:colorectum (human)
associated with pancreatic cancer; protein:increased expression:liver, pancreas (human)
RGD PMID:30770989 PMID:23747337 PMID:30770989 RGD:126925751, RGD:126925752, RGD:126925751 NCBI chr 4:118,299,609...118,314,771
Ensembl chr 4:118,299,612...118,314,710
JBrowse link
G Nras neuroblastoma ras oncogene susceptibility ISO human gene in a mouse model;DNA:missense mutations:cds:p.G12V, p.Q61K (human)
associated with colorectal cancer;DNA:mutations:exons (human)
associated with melanoma;DNA:mutations: exons (human)
RGD PMID:26799184 PMID:28011498 PMID:28787433 RGD:14696774, RGD:14696792, RGD:14696791 NCBI chr 3:102,965,643...102,975,230
Ensembl chr 3:102,965,601...102,975,230
JBrowse link
G Ptprb protein tyrosine phosphatase receptor type B treatment IMP mouse tumor cells in mouse recipient RGD PMID:31348125 RGD:151660353 NCBI chr10:116,111,407...116,225,443
Ensembl chr10:116,111,428...116,225,440
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 disease_progression IMP
ISO
mRNA:increased expression:liver (human) RGD PMID:30404068 PMID:30404068 RGD:152995463, RGD:152995463 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882
JBrowse link
G Rnf43 ring finger protein 43 ISO associated with colorectal adenocarcinoma;mRNA:increased expression:liver (human) RGD PMID:28789449 RGD:151361221 NCBI chr11:87,553,913...87,626,365
Ensembl chr11:87,553,548...87,626,365
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 severity ISO associated with colon adenocarcinoma RGD PMID:11745822 RGD:151361130 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 severity ISO associated with colon cancer
associated with colon adenocarcinoma
RGD PMID:11718450 PMID:11745822 RGD:151361129, RGD:151361130 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Smad4 SMAD family member 4 treatment ISO associated with colorectal carcinoma; DNA:mutations: :
associated with colorectal carcinoma;protein:decreased expression:colorectum:
RGD PMID:29551247 PMID:17390050 RGD:18937000, RGD:21066338 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
JBrowse link
G Sox30 SRY (sex determining region Y)-box 30 ameliorates IDA RGD PMID:29739711 RGD:151660333 NCBI chr11:45,869,873...45,908,824
Ensembl chr11:45,871,137...45,908,821
JBrowse link
G Src Rous sarcoma oncogene disease_progression ISO associated with colon cancer;protein:increased activity:colon RGD PMID:7678609 RGD:150521542 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with colorectal carcinoma;mRNA,protein:increased expression:liver: RGD PMID:22156924 RGD:15014782 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
lung metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam28 a disintegrin and metallopeptidase domain 28 ameliorates ISO associated with lung carcinoma, breast carcinoma
associated with lung adenocarcinoma;
RGD PMID:22636800 PMID:26800504 RGD:153297785, RGD:11531771 NCBI chr14:68,842,447...68,893,338
Ensembl chr14:68,843,476...68,893,291
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 IMP associated with Mammary Neoplasms, Experimental RGD PMID:20860838 RGD:126848767 NCBI chr12:52,550,555...52,618,761
Ensembl chr12:52,550,755...52,618,758
JBrowse link
G Arid2 AT-rich interaction domain 2 exacerbates ISO associated with hepatocellular carcinoma, RGD PMID:32071245 RGD:150340708 NCBI chr15:96,185,403...96,303,344
Ensembl chr15:96,185,399...96,302,873
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc ameliorates ISO associated with hepatocellular carcinoma; RGD PMID:27993894 PMID:26902423 RGD:153350132, RGD:153350133 NCBI chr 5:137,979,783...137,988,495
Ensembl chr 5:137,979,782...137,988,495
JBrowse link
G Car12 carbonic anhydrase 12 ameliorates ISO associated with breast cancer; RGD PMID:29786141 RGD:155226861 NCBI chr 9:66,619,026...66,674,127
Ensembl chr 9:66,620,968...66,674,127
JBrowse link
G Cblb Casitas B-lineage lymphoma b severity ISO associated with stomach carcinoma; RGD PMID:28334634 RGD:150540337 NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411
JBrowse link
G Ccng1 cyclin G1 IMP RGD PMID:30565428 RGD:151361205 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates ISO associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr 6:125,073,144...125,107,554
Ensembl chr 6:125,072,944...125,107,554
JBrowse link
G Col10a1 collagen, type X, alpha 1 ameliorates ISO associated with H1299 cell RGD PMID:33324550 RGD:150429752 NCBI chr10:34,265,977...34,273,081
Ensembl chr10:34,265,977...34,273,081
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ameliorates ISO
IMP
associated with colorectal cancer; human cells in mouse model
associated with nasopharynx carcinoma; human cells in mouse model
associated with osteosarcoma and melanoma
RGD PMID:31938138 PMID:16000558 PMID:26498029 PMID:18071913 RGD:151665329, RGD:151893515, RGD:152023752, RGD:152177473 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 IMP RGD PMID:29483153 RGD:151347599 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Ddr2 discoidin domain receptor family, member 2 exacerbates ISO associated with tongue squamous cell carcinoma; RGD PMID:24556606 RGD:150429746 NCBI chr 1:169,799,874...169,938,525
Ensembl chr 1:169,799,876...169,938,331
JBrowse link
G Fasn fatty acid synthase ISO associated with head and neck squamous cell carcinoma RGD PMID:20604875 RGD:126790467 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fosl2 fos-like antigen 2 ISO human cells in mouse model RGD PMID:30326930 RGD:153344557 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
JBrowse link
G Hilpda hypoxia inducible lipid droplet associated ISO human cells in mouse model RGD PMID:31142329 RGD:153344574 NCBI chr 6:29,272,487...29,275,448
Ensembl chr 6:29,272,487...29,275,445
JBrowse link
G Iqsec1 IQ motif and Sec7 domain 1 ISO human cells in mouse model RGD PMID:18084281 RGD:153344604 NCBI chr 6:90,636,578...90,965,766
Ensembl chr 6:90,633,070...90,965,667
JBrowse link
G Itgav integrin alpha V treatment ISO human cells in rat model RGD PMID:20841470 RGD:152998949 NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ameliorates IMP associated with breast carcinoma RGD PMID:16568086 RGD:150573808 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ameliorates ISO associated with clear cell renal cell carcinoma RGD PMID:23982215 RGD:151356974 NCBI chr18:4,331,325...4,352,978
Ensembl chr18:4,331,327...4,353,015
JBrowse link
G Mir423 microRNA 423 ISO human cells in mouse model RGD PMID:30326930 RGD:153344557 NCBI chr11:76,968,890...76,968,998
Ensembl chr11:76,968,890...76,968,998
JBrowse link
G Mir494 microRNA 494 ameliorates ISO associated with hepatocellular carcinoma RGD PMID:25820676 PMID:28055013 RGD:155900754, RGD:156430322 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836
JBrowse link
G Mir744 microRNA 744 treatment ISO associated with nasopharynx carcinoma RGD PMID:25961434 RGD:11056278 NCBI chr11:65,625,559...65,625,658
Ensembl chr11:65,625,559...65,625,658
JBrowse link
G Nf2 neurofibromin 2 ISO associated with hepatocellular carcinoma RGD PMID:26443326 RGD:11076529 NCBI chr11:4,715,845...4,799,544
Ensembl chr11:4,715,845...4,799,536
JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 ameliorates IMP associated with mammary carcinoma RGD PMID:20802235 RGD:150520014 NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760
JBrowse link
G Pagr1a PAXIP1 associated glutamate rich protein 1A ISO human cells in mouse model RGD PMID:33833989 RGD:153344568 NCBI chr 7:126,614,223...126,616,524
Ensembl chr 7:126,614,205...126,616,524
Ensembl chr 7:126,614,205...126,616,524
JBrowse link
G Ptprb protein tyrosine phosphatase receptor type B treatment IMP RGD PMID:23899555 RGD:151660352 NCBI chr10:116,111,407...116,225,443
Ensembl chr10:116,111,428...116,225,440
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO
IMP
human cells in mouse model RGD PMID:20978191 PMID:29809146 RGD:152995469, RGD:152995516 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 IMP RGD PMID:29809146 RGD:152995516 NCBI chr11:119,493,731...119,790,417
Ensembl chr11:119,493,731...119,790,402
JBrowse link
G Sf3b4 splicing factor 3b, subunit 4 ISO human cells in mouse model RGD PMID:30391496 RGD:155804298 NCBI chr 3:96,079,822...96,084,880
Ensembl chr 3:96,079,648...96,084,880
JBrowse link
G Sox30 SRY (sex determining region Y)-box 30 ameliorates IDA RGD PMID:29739711 RGD:151660333 NCBI chr11:45,869,873...45,908,824
Ensembl chr11:45,871,137...45,908,821
JBrowse link
G Src Rous sarcoma oncogene treatment
ameliorates
ISO associated with breast cancer;
associated with nasopharynx carcinoma;
RGD PMID:15753384 PMID:27078847 RGD:1581400, RGD:150521726 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
Lymphatic Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca13 ATP-binding cassette, sub-family A member 13 susceptibility ISO DNA:amplification:cds: (human, male) RGD PMID:27366209 RGD:152995256 NCBI chr11:9,141,942...9,634,871
Ensembl chr11:9,141,942...9,634,259
JBrowse link
G Adam28 a disintegrin and metallopeptidase domain 28 ISO associated with breast cancer;DNA:hypermethylation: RGD PMID:25620615 RGD:153298970 NCBI chr14:68,842,447...68,893,338
Ensembl chr14:68,843,476...68,893,291
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 disease_progression ISO associated with stomach cancer; RGD PMID:11172604 RGD:13831357 NCBI chr15:74,388,045...74,461,314
Ensembl chr15:74,388,044...74,461,314
JBrowse link
G Aicda activation-induced cytidine deaminase ISO associated with stomach cancer;protein:increased expression:stomach (human) RGD PMID:21538122 RGD:127285638 NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139
JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: therapeutic CTD PMID:17130448 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Aqp3 aquaporin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 ISO associated with nasopharynx carcinoma;mRNA, protein:increased expression: epithelium of nasopharynx RGD PMID:25961434 RGD:11056278 NCBI chr12:52,550,555...52,618,761
Ensembl chr12:52,550,755...52,618,758
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 ISO associated with colorectal cancer RGD PMID:32317519 RGD:126779580 NCBI chr 2:153,187,750...153,245,927
Ensembl chr 2:153,187,749...153,245,927
JBrowse link
G Axl AXL receptor tyrosine kinase ISO associated Pancreatic Neoplasms RGD PMID:19252414 RGD:2325833 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
JBrowse link
G Bag1 BCL2-associated athanogene 1 disease_progression ISO associated with Breast Neoplasms:protein:increased expression:breast RGD PMID:18430249 RGD:2292908 NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO associated with stomach cancer; protein:increased expression: : RGD PMID:24752577 RGD:14390158 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404
JBrowse link
G Barhl2 BarH like homeobox 2 ISO associated with oral squamous cell carcinoma; mRNA:decreased expression:mouth mucous RGD PMID:27542258 RGD:14390167 NCBI chr 5:106,600,389...106,606,032
Ensembl chr 5:106,600,389...106,606,032
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO associated with Breast Neoplasms;protein:increased expression:lymph node RGD PMID:18217456 RGD:2293013 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bik BCL2-interacting killer ISO associated with cholangiocarcinoma;DNA:CNV:: RGD PMID:16865775 RGD:14394820 NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO associated with Cervix Neoplasms;mRNA:splice variant
associated with Breast Neoplasms
RGD PMID:17877643 PMID:17285241 RGD:2293098, RGD:2293103 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Braf Braf transforming gene ISO CTD Direct Evidence: marker/mechanism CTD PMID:29426936 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Brd7 bromodomain containing 7 severity ISO protein:increased expression:lung: RGD PMID:22008115 RGD:9586442 NCBI chr 8:89,056,522...89,089,249
Ensembl chr 8:89,057,667...89,088,822
JBrowse link
G Bsg basigin disease_progression ISO associated with Breast Neoplasms RGD PMID:16004819 RGD:2289055 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803
JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase disease_progression ISO associated with lung adenocarcinoma;protein:increased expression:lung (human) RGD PMID:31200752 RGD:151347847 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319
JBrowse link
G Cab39 calcium binding protein 39 ISO associated with pancreatic cancer;RNA:increased expression:pancreas RGD PMID:28197410 RGD:14398834 NCBI chr 1:85,707,796...85,779,298
Ensembl chr 1:85,721,162...85,779,297
JBrowse link
G Car9 carbonic anhydrase 9 ISO associated with Cervix Neoplasms RGD PMID:17233814 RGD:2293196 NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729
JBrowse link
G Casp9 caspase 9 ISO associated with Carcinoma, Non-Small-Cell Lung;DNA:SNP:exon:rs1052576 (human) RGD PMID:17285546 RGD:13434907 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cav1 caveolin 1, caveolae protein disease_progression ISO associated with Melanoma RGD PMID:22134245 RGD:8661767 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Cbl Casitas B-lineage lymphoma ISO associated with stomach carcinoma;protein:increased expression:stomach RGD PMID:31611438 RGD:126925223 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346
JBrowse link
G Cblb Casitas B-lineage lymphoma b ISO associated with stomach carcinoma; RGD PMID:20038312 RGD:150540338 NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411
JBrowse link
G Ccnd2 cyclin D2 ISO associated with colorectal cancer;protein:increased expression:colorectum RGD PMID:19508551 RGD:151665111 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
JBrowse link
G Ccne1 cyclin E1 ISO associated with Carcinoma, Transitional Cell;protein:decreased expression RGD PMID:16949911 RGD:2289266 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Ccnh cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr13:85,337,504...85,361,850
Ensembl chr13:85,337,527...85,371,588
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO associated with Breast Neoplasms;mRNA:increased expression:lymph node RGD PMID:24301790 RGD:8551816 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
JBrowse link
G Cd274 CD274 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:16530813 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd40 CD40 antigen ISO associated with breast cancer;DNA:snps:5' utr, intron:c.-1T>C, c.51+914T>G (rs1883832, rs4810485) (human) RGD PMID:21912605 RGD:8547780 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cd44 CD44 antigen ISO associated with Breast Neoplasms, Colorectal Neoplasms, Stomach Neoplasms;mRNA, protein:splice variant, increased expression:breast, large intestine, stomach RGD PMID:16425351 RGD:2289356 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cdh1 cadherin 1 ISO associated with Cervix Neoplasms
associated with Breast Neoplasms
RGD PMID:18097581 PMID:17649807 RGD:2296046, RGD:2289498 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO associated with Eyelid Neoplasms;
associated with Oral Squamous Cell Carcinoma;
RGD PMID:19628749 PMID:15817070 RGD:8661799, RGD:8662374 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO associated with Breast Neoplasms
associated with non-small cell lung carcinoma
RGD PMID:12015771 PMID:28601655 RGD:2293607, RGD:13673921 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29426936 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Cldn1 claudin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33665778 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
JBrowse link
G Clptm1l CLPTM1-like ISO associated with esophagus squamous cell carcinoma; mRNA:increased expression:esophagus RGD PMID:25480402 RGD:150530497 NCBI chr13:73,752,121...73,768,758
Ensembl chr13:73,752,125...73,768,724
JBrowse link
G Clu clusterin ISO associated with breast cancer;DNA:snp:promoter:g.27611345C>G (rs9331888) (human) RGD PMID:22037783 RGD:8963167 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
JBrowse link
G Comt catechol-O-methyltransferase ISO associated with breast cancer;DNA:missense mutation:cds:p.V108/158M (human) RGD PMID:10755383 RGD:8662330 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Crp C-reactive protein, pentraxin-related susceptibility ISO associated with Breast Neoplasm; DNA:polymorphism: :1846C>T(rs1205)(human) RGD PMID:24633920 RGD:9580226 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO associated with Breast Neoplasms RGD PMID:14734466 RGD:2293711 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IMP associated with Prostatic Neoplasms RGD PMID:10611340 RGD:4891523 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Ctnna1 catenin alpha 1 ISO associated with Breast Neoplasms RGD PMID:12047765 RGD:2289795 NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
JBrowse link
G Ctnnb1 catenin beta 1 ISO associated with Breast Neoplasms;protein:decreased expression RGD PMID:17908479 RGD:2289813 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 disease_progression ISO associated with stomach cancer;mRNA:increased expression:stomach (human) RGD PMID:21633638 RGD:152023624 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO associated with nasopharynx carcinoma; protein:increased expression:lymph node (human) RGD PMID:16000558 RGD:151893515 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Cycs cytochrome c, somatic ISO associated with non-small cell lung carcinoma; protein:decreased expression:serum RGD PMID:25578497 RGD:13792769 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 severity ISO mRNA, protein:increased expression:mouth (human)
mRNA:increased expression:kidney, lymph nodes (human)
RGD PMID:31253192 PMID:27020590 RGD:151347620, RGD:151347863 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Ddr2 discoidin domain receptor family, member 2 disease_progression ISO associated with oral squamous cell carcinoma RGD PMID:29945346 RGD:150429700 NCBI chr 1:169,799,874...169,938,525
Ensembl chr 1:169,799,876...169,938,331
JBrowse link
G Dnmt3b DNA methyltransferase 3B ISO associated with Carcinoma, Pancreatic Ductal; RGD PMID:22919364 RGD:9589121 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
JBrowse link
G Ebag9 estrogen receptor-binding fragment-associated gene 9 ISO associated with Prostatic Neoplasm;protein:increased expression:prostate gland, lymph node
associated with Breast Neoplasms;protein:increased expression:breast
RGD PMID:12845666 PMID:12054692 PMID:17187007 RGD:2289856, RGD:2298489, RGD:2289847 NCBI chr15:44,482,574...44,504,916
Ensembl chr15:44,482,571...44,504,911
JBrowse link
G Egfr epidermal growth factor receptor treatment IMP associated with Squamous Cell Carcinoma of the Tongue RGD PMID:19380367 RGD:8551769 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 ISO associated with Melanoma;
associated with Esophageal Squamous Cell Carcinoma;
RGD PMID:24658378 PMID:24805087 RGD:9590069, RGD:9590071 NCBI chr17:35,117,427...35,133,049
Ensembl chr17:35,117,445...35,133,028
JBrowse link
G Epha2 Eph receptor A2 ISO protein:increased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO associated with Breast Neoplasms;DNA, protein:polymorphism, increased expression:serum:p.I655V
associated with lung adenocarcinoma; protein:increased expression:lung (human)
CTD Direct Evidence: marker/mechanism
associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder
RGD
CTD
PMID:21532492 PMID:21966491 PMID:18237248 PMID:18097576 RGD:153344600, RGD:2289925, RGD:2289926 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO associated with Prostatic Neoplasms;protein:increased expression, altered localization:lymph node, nucleus
associated with head and neck squamous cell carcinoma
RGD PMID:17634423 PMID:20604875 RGD:2289944, RGD:126790467 NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression
severity
ISO associated with oral squamous cell carcinoma
associated with lung non-small cell carcinoma
associated with colorectal adenocarcinoma
RGD PMID:27444519 PMID:21324275 PMID:16507107 RGD:126781762, RGD:126790471, RGD:126781766 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO associated with Cervix Neoplasms;DNA:polymorphism:promoter:-1377G>A RGD PMID:18068525 RGD:2298509 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fgf1 fibroblast growth factor 1 ISO associated with Cervix Neoplasms;mRNA:increased expression:lymph node RGD PMID:17242701 RGD:2290286 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO associated with breast cancer;DNA:snp:intron:c.109+7033T>A (rs1219648) (human) RGD PMID:20640597 RGD:7394846 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
JBrowse link
G Flt3 FMS-like tyrosine kinase 3 disease_progression IMP associated with Prostatic Neoplasms RGD PMID:14566827 RGD:2302210 NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
JBrowse link
G Foxa1 forkhead box A1 ISO associated with lung non-small cell carcinoma; mRNA:increased expression: : RGD PMID:29115441 RGD:151665751 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702
JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25485836 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO associated with stomach carcinoma; DNA:hypermethylation:promoter RGD PMID:23071548 RGD:151665353 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
JBrowse link
G Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr10:48,969,776...49,666,523
Ensembl chr10:48,970,929...49,664,862
JBrowse link
G Hmgb1 high mobility group box 1 ISO associated with Adenocarcinoma, Colon RGD PMID:20616616 RGD:10402080 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Breast Neoplasms RGD PMID:21590495 RGD:8547712 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ier2 immediate early response 2 ISO RGD PMID:22120713 RGD:153323322 NCBI chr 8:85,387,960...85,389,481
Ensembl chr 8:85,387,960...85,389,483
JBrowse link
G Il13 interleukin 13 ISO associated with Melanoma, Cutaneous Malignant;mRNA:increased expression:lymph node RGD PMID:17545514 RGD:8549587 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il18 interleukin 18 ISO associated with Breast Neoplasms;protein:increased expression:serum RGD PMID:12902898 RGD:8655867 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Ing4 inhibitor of growth family, member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:27806345 NCBI chr 6:125,016,811...125,026,228
Ensembl chr 6:125,016,723...125,026,228
JBrowse link
G Iqsec1 IQ motif and Sec7 domain 1 disease_progression ISO associated with lung adenocarcinoma; protein:increased expression:lung (human) RGD PMID:21966491 RGD:153344600 NCBI chr 6:90,636,578...90,965,766
Ensembl chr 6:90,633,070...90,965,667
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) ISO associated with non-small cell lung carcinoma, RGD PMID:28537888 RGD:13792830 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34755307 NCBI chr11:60,912,970...60,964,095
Ensembl chr11:60,913,390...60,961,957
JBrowse link
G Kdr kinase insert domain protein receptor treatment IMP associated with Squamous Cell Carcinoma of the Tongue RGD PMID:19380367 RGD:8551769 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor ISO CTD Direct Evidence: therapeutic CTD PMID:21383688 NCBI chr 1:133,249,625...133,257,460
Ensembl chr 1:133,237,565...133,257,460
Ensembl chr 1:133,237,565...133,257,460
JBrowse link
G Klf7 Kruppel-like transcription factor 7 (ubiquitous) ISO CTD Direct Evidence: therapeutic CTD PMID:37734194 NCBI chr 1:64,068,607...64,161,504
Ensembl chr 1:64,068,606...64,161,441
JBrowse link
G Kmt2d lysine (K)-specific methyltransferase 2D ISO associated with stomach cancer RGD PMID:30177394 RGD:150521710 NCBI chr15:98,729,550...98,771,958
Ensembl chr15:98,729,550...98,769,085
JBrowse link
G Lamc2 laminin, gamma 2 ISO associated with lung squamous cell carcinoma; RGD PMID:23124251 RGD:13793371 NCBI chr 1:152,998,502...153,062,193
Ensembl chr 1:152,998,502...153,062,193
JBrowse link
G Lrrc59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr11:94,520,603...94,536,049
Ensembl chr11:94,520,593...94,536,042
JBrowse link
G Macir macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 1:97,571,627...97,589,743
Ensembl chr 1:97,534,043...97,589,799
JBrowse link
G Met met proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:29426936 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mir125a microRNA 125a ISO associated with stomach cancer; RGD PMID:22322911 RGD:21408544 NCBI chr17:18,051,074...18,051,141
Ensembl chr17:18,051,074...18,051,141
JBrowse link
G Mir152 microRNA 152 ISO associated with breast cancer RGD PMID:22935141 RGD:19165152 NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291
JBrowse link
G Mir155 microRNA 155 disease_progression ISO associated with colon cancer RGD PMID:26885061 PMID:29893326 PMID:27856635 RGD:21079444, RGD:21409756, RGD:21079446 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
JBrowse link
G Mir187 microRNA 187 ISO associated with oral squamous cell carcinoma; RNA:increased expression:plasma RGD PMID:27542258 RGD:14390167 NCBI chr18:24,562,167...24,562,227
Ensembl chr18:24,562,167...24,562,227
JBrowse link
G Mir224 microRNA 224 ISO associated with colorectal cancer; mRNA:decreased expression:colorectal mucosa: RGD PMID:25919696 RGD:14398749 NCBI chr  X:71,304,637...71,304,718
Ensembl chr  X:71,304,637...71,304,718
JBrowse link
G Mir30a microRNA 30a ISO associated with Colorectal Neoplasms RGD PMID:23486085 RGD:13432035 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420
JBrowse link
G Mir335 microRNA 335 ISO associated with stomach cancer; RNA:decreased expression:stomach RGD PMID:21822301 RGD:14394425 NCBI chr 6:30,741,298...30,741,395
Ensembl chr 6:30,741,298...30,741,395
JBrowse link
G Mir432 microRNA 432 disease_progression ISO mRNA:decreased expression:colon (human) RGD PMID:33717244 RGD:152999433 NCBI chr12:109,561,390...109,561,464
Ensembl chr12:109,561,390...109,561,464
JBrowse link
G Mmp2 matrix metallopeptidase 2 disease_progression ISO associated with Tongue Neoplasms
associated with Carcinoma, Ductal, Breast
RGD PMID:23107277 PMID:23280016 RGD:8547824, RGD:8655998 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO associated with breast cancer;DNA:deletion:promoter:-1170_-1172delA (human) RGD PMID:15161710 RGD:8662937 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO associated with Carcinoma, Non-Small-Cell Lung;protein:increased expression:serum
associated with Tongue Neoplasms
associated with Endometrial Neoplasms;protein:increased expression:endometrium
RGD PMID:20704821 PMID:23107277 PMID:12487935 RGD:5129215, RGD:8547824, RGD:2298523 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Msh2 mutS homolog 2 ISO associated with laryngeal squamous cell carcinoma RGD PMID:24459922 RGD:126848797 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
JBrowse link
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22644300 NCBI chr17:25,967,587...25,973,352
Ensembl chr17:25,967,587...25,973,352
JBrowse link
G Mta1 metastasis associated 1 ISO associated with Carcinoma, Non-Small-Cell Lung;mRNA:increased expression:lung RGD PMID:11804687 RGD:9588220 NCBI chr12:113,061,830...113,100,826
Ensembl chr12:113,061,898...113,100,826
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Muc1 mucin 1, transmembrane ISO associated with Common Bile Duct Neoplasms
associated with Esophageal Neoplasms
associated with Carcinoma, Renal Cell;
associated with Gallbladder Neoplasms;protein:altered localization:gallbladder
RGD PMID:16222735 PMID:21339746 PMID:10390012 PMID:11295067 RGD:2324649, RGD:7349383, RGD:7245968, RGD:2324860 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric ISO associated with chloangiocarcinoma;protein:increased expression:bile duct RGD PMID:16842244 RGD:2325168 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Ncam1 neural cell adhesion molecule 1 IMP RGD PMID:10086383 RGD:2326067 NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO associated with Cervix Neoplasms; associated with Endometrial Neoplasms
associated with Breast Neoplasms
RGD PMID:8855975 PMID:8102131 PMID:9036878 RGD:2299062, RGD:2299077, RGD:2299061 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO associated with Cervix Neoplasms; associated with Endometrial Neoplasms RGD PMID:8855975 RGD:2299062 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell susceptibility ISO associated with Breast Neoplasms;DNA:polymorphisms:promoter, exon:-786T>C,p.E298D (human) RGD PMID:17262178 RGD:2292070 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 ISO associated with breast cancer;DNA:missense mutation:cds:p.S326C (rs1052133) (human) RGD PMID:18977234 RGD:8657156 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029
JBrowse link
G Pagr1a PAXIP1 associated glutamate rich protein 1A disease_progression ISO protein:decreased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr 7:126,614,223...126,616,524
Ensembl chr 7:126,614,205...126,616,524
Ensembl chr 7:126,614,205...126,616,524
JBrowse link
G Pdgfa platelet derived growth factor, alpha ISO associated with Breast Neoplasms;mRNA:increased expression:breast RGD PMID:8619189 RGD:2292155 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO associated with Breast Neoplasms;mRNA:increased expression:lymph node RGD PMID:17674348 RGD:2292173 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO associated with non-small cell lung carcinoma;mRNA:increased expression:blood serum RGD PMID:25064732 RGD:13503320 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898
JBrowse link
G Pdpn podoplanin ISO associated with Breast Neoplasms
associated with Cervix Neoplasms
RGD PMID:18165897 PMID:16528371 RGD:2292231, RGD:2292237 NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO associated with Breast Neoplasms
associated with Cervix Neoplasms
RGD PMID:16243812 PMID:18191186 RGD:2302868, RGD:2302867 NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO associated with Colorectal Neoplasms RGD PMID:25550888 RGD:13432030 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO associated with Colorectal Neoplasms RGD PMID:25550888 RGD:13432030 NCBI chr 9:98,920,455...99,022,264
Ensembl chr 9:98,918,707...99,022,674
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:34755307 NCBI chr 3:94,965,841...95,014,241
Ensembl chr 3:94,965,841...95,014,241
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 ISO associated with Seminoma; associated with Carcinoma, Embryonal RGD PMID:15386301 RGD:2292442 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO associated with Cholangiocarcinoma;protein:increased expression:bile duct epithelium RGD PMID:20021832 RGD:2317459 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 ISO associated with Prostatic Neoplasms RGD PMID:19305425 RGD:2314605 NCBI chr 2:166,408,265...166,555,752
Ensembl chr 2:166,408,262...166,555,752
JBrowse link
G Pten phosphatase and tensin homolog ISO associated with Prostatic Neoplasms;protein:decreased expression:prostate
associated with Breast Neoplasms
RGD PMID:17163422 PMID:17919877 RGD:2292507, RGD:2292499 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO associated with Biliary Tract Neoplasms
associated with carcinoma, non-small-cell lung; DNA:SNP: :929G>C(human)
associated with Breast Neoplasms
RGD PMID:18159174 PMID:20016751 PMID:18353210 RGD:2317165, RGD:5135471, RGD:2300128 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 ISO associated with lung squamous cell carcinoma; protein:increased tyrosine phosphorylation:lymph node RGD PMID:23906871 RGD:152176664 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 ISO associated with lung squamous cell carcinoma; protein:decreased expression:lymph node RGD PMID:23906871 RGD:152176664 NCBI chr 5:103,573,058...103,746,227
Ensembl chr 5:103,573,058...103,746,169
JBrowse link
G Ramp2 receptor (calcitonin) activity modifying protein 2 disease_progression ISO associated with colorectal cancer; protein:increased expression:lymph node (human) RGD PMID:23634287 RGD:151708733 NCBI chr11:101,137,160...101,139,076
Ensembl chr11:101,136,854...101,150,372
JBrowse link
G Ramp3 receptor (calcitonin) activity modifying protein 3 ISO associated with colorectal cancer; protein:increased expression:lymph node (human) RGD PMID:23634287 RGD:151708733 NCBI chr11:6,608,507...6,627,478
Ensembl chr11:6,608,521...6,627,475
JBrowse link
G Rassf2 Ras association (RalGDS/AF-6) domain family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17013896 NCBI chr 2:131,834,770...131,872,336
Ensembl chr 2:131,831,335...131,872,178
JBrowse link
G Rbm10 RNA binding motif protein 10 ISO associated with lung adenocarcinoma;DNA:missense mutation:exon:p.R241C (c.763C>T) (human) RGD PMID:30405763 RGD:151356993 NCBI chr  X:20,483,596...20,517,128
Ensembl chr  X:20,483,742...20,517,140
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO associated with Prostatic Neoplasms;protein:altered localization:nucleus, prostate gland RGD PMID:17020979 RGD:2298757 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Ret ret proto-oncogene ISO associated with Pancreatic Neoplasms RGD PMID:18652760 RGD:2324925 NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679
JBrowse link
G Rhoa ras homolog family member A ISO associated with Bladder Neoplasms;protein:increased expression:lymph node
associated with colorectal cancer
RGD PMID:12855641 PMID:17597401 RGD:2298872, RGD:13432052 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO associated with breast ductal carcinoma; protein:increased expression:breast tumor, lymph node (human) RGD PMID:20978191 RGD:152995469 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882
JBrowse link
G Runx1 runt related transcription factor 1 ISO associated with Carcinoid Tumor RGD PMID:21636701 RGD:126779567 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
JBrowse link
G Skp2 S-phase kinase-associated protein 2 ISO associated with Endometrial Neoplasms;protein:increased expression:endometrium RGD PMID:16080017 RGD:2315043 NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 severity ISO associated with stomach carcinoma
associated with gastric adenocarcinoma;protein:increased expression: :
RGD PMID:25908107 PMID:21501294 RGD:11052781, RGD:151361203 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Smad4 SMAD family member 4 ISO associated with Breast Neoplasms RGD PMID:11809701 RGD:2300007 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
JBrowse link
G Smo smoothened, frizzled class receptor ISO associated with colorectal cancer RGD PMID:30784110 RGD:150520177 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364
JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:15221989 RGD:6478801 NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746
JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO associated with Prostatic Neoplasms RGD PMID:16707422 RGD:2298925 NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO associated with Breast Neoplasms RGD PMID:18097573 RGD:2298901 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial disease_progression ISO associated with tongue neoplasms;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:10853026 PMID:19381893 PMID:20618948 PMID:20618948 RGD:8547519 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 disease_progression ISO associated with Breast Neoplasms RGD PMID:24382260 RGD:8661670 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610
JBrowse link
G Src Rous sarcoma oncogene ISO associated with colon adenocarcinoma, RGD PMID:21282564 RGD:150520218 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) ISO associated with Endometrial Neoplasms RGD PMID:19443387 RGD:2315087 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549414 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stk11 serine/threonine kinase 11 ISO associated with Breast Neoplasms;protein:decreased expression RGD PMID:12114407 RGD:2291948 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
JBrowse link
G Tert telomerase reverse transcriptase disease_progression ISO associated with lung non-small cell carcinoma; RGD PMID:11679180 RGD:152977755 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 ISO associated with Endometrial Neoplasms;protein:increased expression:endometrium RGD PMID:12487935 RGD:2298523 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 ISO associated with Breast Neoplasms;mRNA:increased expression:breast RGD PMID:12828172 RGD:2290437 NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370
JBrowse link
G Timp4 tissue inhibitor of metalloproteinase 4 ISO associated with Breast Neoplasms;mRNA:increased expression:breast RGD PMID:12828172 RGD:2290437 NCBI chr 6:115,221,405...115,229,166
Ensembl chr 6:115,218,853...115,229,166
JBrowse link
G Tlr4 toll-like receptor 4 ISO associated with Carcinoma, Ductal, Breast; RGD PMID:23338716 RGD:7794684 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Trmt11 tRNA methyltransferase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr10:30,410,218...30,477,598
Ensembl chr10:30,410,221...30,476,745
JBrowse link
G Trp53 transformation related protein 53 ISO
IMP
associated with Penile Neoplasms
associated with Carcinoma, Squamous Cell;
associated with Breast Neoplasms;DNA:missense mutation, duplication:cds, intron:p.R72P
RGD PMID:18268397 PMID:18059331 PMID:18230179 RGD:2290533, RGD:8547790, RGD:2290534 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888
JBrowse link
G Tsc2 TSC complex subunit 2 ISO associated with Breast Neoplasms RGD PMID:15951164 RGD:11568707 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
JBrowse link
G Tshr thyroid stimulating hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9062474 NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582
JBrowse link
G Ttr transthyretin ISO associated with colorectal cancer;protein:decreased expresion:blood serum (human) RGD PMID:21074777 RGD:151665155 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378
JBrowse link
G Tymp thymidine phosphorylase ISO associated with Cholangiocarcinoma
associated with Breast Neoplasms
RGD PMID:11927969 PMID:10685502 RGD:2325027, RGD:2293725 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242
JBrowse link
G Vegfa vascular endothelial growth factor A ISO
IMP
associated with Cervix Neoplasms
associated with Breast neoplasms;
RGD PMID:19783962 PMID:17597103 RGD:2315454, RGD:7421574 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfc vascular endothelial growth factor C exacerbates
disease_progression
ISO associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder
associated with pancreatic adenocarcinoma;protein:increased expression:pancreas (human)
associated with Lymphatic Metastasis;
associated with thyroid diseases;mRNA:increased expression:thyroid gland:
associated with Breast Neoplasms
associated with Prostatic Neoplasms
associated with Cervix Neoplasms
RGD PMID:17034609 PMID:18061373 PMID:15289890 PMID:12203051 PMID:19923084 More... RGD:2315484, RGD:155630642, RGD:7488946, RGD:7483611, RGD:2315469, RGD:2315474, RGD:2315475 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
JBrowse link
G Vegfd vascular endothelial growth factor D ISO associated with Cervix Neoplasms
associated with Breast Neoplasms
RGD PMID:19589137 PMID:17951197 RGD:2315475, RGD:2315480 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646
JBrowse link
G Wrap53 WD repeat containing, antisense to Trp53 ISO associated with lung non-small cell carcinoma;
associated with esophagus squamous cell carcinoma;
RGD PMID:31281482 PMID:24626331 RGD:21081513, RGD:21081532 NCBI chr11:69,452,580...69,471,076
Ensembl chr11:69,452,584...69,471,081
JBrowse link
Neoplasm Micrometastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cycs cytochrome c, somatic ISO associated with non-small cell lung carcinoma; protein:decreased expression:serum RGD PMID:25578497 RGD:13792769 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
Neoplasm Seeding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27224422 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18301
    disease of cellular proliferation 7493
      Neoplastic Processes 746
        Neoplasm Metastasis 502
          Bone Metastasis 7
          Circulating Neoplastic Cells 1
          Extranodal Extension 0
          Liver Metastasis 42
          Lymphatic Metastasis 161
          Neoplasm Micrometastasis 1
          Neoplasm Seeding 1
          Unknown Primary Neoplasms 0
          leptomeningeal metastasis 0
          lung metastasis 31
Path 2
Term Annotations click to browse term
  disease 18301
    Pathological Conditions, Signs and Symptoms 12359
      Pathologic Processes 7726
        Neoplastic Processes 746
          Neoplasm Metastasis 502
            Bone Metastasis 7
            Circulating Neoplastic Cells 1
            Extranodal Extension 0
            Liver Metastasis 42
            Lymphatic Metastasis 161
            Neoplasm Micrometastasis 1
            Neoplasm Seeding 1
            Unknown Primary Neoplasms 0
            leptomeningeal metastasis 0
            lung metastasis 31
paths to the root