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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Burkholderia Infections
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Accession:DOID:9000739 term browser browse the term
Definition:Infections with bacteria of the genus BURKHOLDERIA.
Synonyms:exact_synonym: Burkholderia Infection
 primary_id: MESH:D019121
 xref: EFO:1001280


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melioidosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifna1 interferon, alpha 1 ISO mRNA:increased expression:PBMC RGD PMID:28435890 RGD:36174031 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:103,097,356...103,097,925 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:19114913 RGD:36049801 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:20142364 RGD:6484129 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Serpinf1 serpin family F member 1 severity ISO protein:increased expression:plasma (human) RGD PMID:23992406 PMID:23992406 PMID:25370187 RGD:36174010, RGD:36174010, RGD:36174011 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Tlr5 toll-like receptor 5 ISO mRNA:increased expression:blood, monocyte, granulocyte (human)
ClinVar Annotator: match by term: Melioidosis, resistance to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM
RGD		 PMID:14623910 PMID:16027372 PMID:23447684 PMID:17676990 RGD:5129511 NCBI chr13:97,166,430...97,190,642
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 severity
treatment		 ISO RGD PMID:18008257 PMID:18008257 PMID:18008257 RGD:126928120, RGD:126928120, RGD:126928120 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19139
    disease by infectious agent 2255
      Bacterial Infections and Mycoses 1117
        bacterial infectious disease 823
          Gram-Negative Bacterial Infections 199
            Burkholderia Infections 6
              glanders 0
              melioidosis 6
paths to the root