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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Syncope
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Accession:DOID:9000727 term browser browse the term
Definition:A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
Synonyms:exact_synonym: Cardiogenic Syncope;   Cardiogenic Syncopes;   Carotid Sinus Syncope;   Carotid Sinus Syncopes;   Convulsive Syncope;   Convulsive Syncopes;   Deglutitional Syncope;   Deglutitional Syncopes;   Drop Attack;   Drop Attacks;   Effort Syncope;   Effort Syncopes;   Fainting;   Hyperventilation Syncope;   Hyperventilation Syncopes;   Micturition Syncope;   Micturition Syncopes;   Postural Syncope;   Postural Syncopes;   Presyncope;   Presyncopes;   Situational Syncope;   Situational Syncopes;   Stokes-Adams Syncope;   Stokes-Adams Syncopes;   Syncopal Episode;   Syncopal Episodes;   Syncopal Vertigo;   Syncopes;   Tussive Syncope;   Tussive Syncopes;   Vertigos, Syncopal
 primary_id: MESH:D013575;   RDO:0003347
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
Syncope term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 ISO ClinVar Annotator: match by term: Syncope ClinVar PMID:23861362 PMID:24033266 PMID:25741868 PMID:26498160 PMID:26899768 PMID:28492532 PMID:30959811 NCBI chr17:66,304,530...66,397,647
Ensembl chr17:66,304,501...66,397,653
JBrowse link
G Ctnna3 catenin alpha 3 ISO ClinVar Annotator: match by term: Syncope ClinVar NCBI chr20:25,063,124...26,640,428
Ensembl chr20:26,516,836...26,589,209
JBrowse link
G Dsp desmoplakin ISO ClinVar Annotator: match by term: Syncope ClinVar PMID:25741868 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 ISO ClinVar Annotator: match by term: Syncope ClinVar PMID:11207363 PMID:12414843 PMID:14504341 PMID:15037716 PMID:15212652 PMID:16449802 PMID:17395131 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Lipt2 lipoyl(octanoyl) transferase 2 ISO ClinVar Annotator: match by term: Syncope ClinVar PMID:11207363 PMID:12414843 PMID:14504341 PMID:15037716 PMID:15212652 PMID:16449802 PMID:17395131 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 1:165,170,645...165,172,972
Ensembl chr 1:165,170,645...165,172,972
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO ClinVar Annotator: match by term: Syncope ClinVar PMID:9668175 PMID:10090880 PMID:10611954 PMID:10612841 PMID:11464238 PMID:16730661 PMID:17489852 PMID:19253030 PMID:19934083 PMID:20041150 PMID:21153919 PMID:21246368 PMID:21413889 PMID:22207183 PMID:23588594 PMID:23907647 PMID:23981758 PMID:24033266 PMID:24251727 PMID:24469716 PMID:24929125 PMID:25741868 PMID:26003477 PMID:27364639 PMID:27733942 PMID:28483595 PMID:28492532 PMID:29543225 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311
JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Syncope ClinVar NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO ClinVar Annotator: match by term: Syncope ClinVar PMID:25741868 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Ttn titin ISO ClinVar Annotator: match by term: Syncope ClinVar PMID:24033266 PMID:25741868 NCBI chr 3:63,565,160...63,837,815 JBrowse link
Vasovagal Syncope term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppb natriuretic peptide B ISO associated with Syncope;protein:increased expression:serum: RGD PMID:23373852 RGD:7247623 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17129
    disease of anatomical entity 16476
      nervous system disease 12074
        Neurologic Manifestations 5408
          Neurobehavioral Manifestations 3679
            Consciousness Disorders 23
              Unconsciousness 23
                Syncope 10
                  Stoll Alembik Dott Syndrome 0
                  Vasovagal Syncope + 1
Path 2
Term Annotations click to browse term
  disease 17129
    disease of anatomical entity 16476
      nervous system disease 12074
        central nervous system disease 10353
          brain disease 9712
            disease of mental health 7022
              cognitive disorder 1949
                Consciousness Disorders 23
                  Unconsciousness 23
                    Syncope 10
                      Stoll Alembik Dott Syndrome 0
                      Vasovagal Syncope + 1
paths to the root