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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Porcine Reproductive and Respiratory Syndrome
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Accession:DOID:9000684 term browser browse the term
Definition:A syndrome characterized by outbreaks of late term abortions, high numbers of stillbirths and mummified or weak newborn piglets, and respiratory disease in young unweaned and weaned pigs. It is caused by PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS. (Radostits et al., Veterinary Medicine, 8th ed, p1048)
Synonyms:exact_synonym: Blue Eared Pig Disease;   Mystery Swine Disease;   PRRS;   Porcine Epidemic Abortion and Respiratory Syndrome;   Swine Infertility and Respiratory Syndrome
 xref: MESH:D019318;   MONDO:0025494


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Porcine Reproductive and Respiratory Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd163 CD163 molecule susceptibility
ameliorates		 ISO RGD PMID:27847356 PMID:30745836 PMID:31440241 RGD:127285645 RGD:127285676 RGD:127285677 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA:increased expression:peripheral blood mononuclear cell (pig) RGD PMID:26022073 RGD:36049793 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19140
    syndrome 11403
      Porcine Reproductive and Respiratory Syndrome 2
Path 2
Term Annotations click to browse term
  disease 19140
    disease by infectious agent 2255
      viral infectious disease 1719
        RNA Virus Infections 1400
          Nidovirales Infections 1028
            Arterivirus Infections 2
              Porcine Reproductive and Respiratory Syndrome 2
paths to the root