RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Pain
Accession: DOID:9000641
browse the term
Definition: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Synonyms: exact_synonym: Ache; Burning Pain; Crushing Pain; Crushing Pains; Migratory Pain; Migratory Pains; Physical Suffering; Physical Sufferings; Radiating Pain; Radiating Pains; aches; burning pains; splitting pain; splitting pains
primary_id: MESH:D010146
xref: EFO:0003843
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Abcb1
ATP binding cassette subfamily B member 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:28193520
NCBI chrNW_004955432:4,911,774...5,085,349
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Adm
adrenomedullin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17043245
NCBI chrNW_004955414:25,951,473...25,953,593
Ensembl chrNW_004955414:25,951,349...25,953,645
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Aif1
allograft inflammatory factor 1
ISO
associated with Diabetes Mellitus, Experimental; protein:increased expression:spinal cord dorsal horn (rat)
RGD
PMID:18186080
RGD:2313034
NCBI chrNW_004955437:157,509...158,919
Ensembl chrNW_004955437:157,509...158,919
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Akt1
AKT serine/threonine kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17084039
NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
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Alb
albumin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:4126124
NCBI chrNW_004955447:9,327...21,212
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Alox5
arachidonate 5-lipoxygenase
ISO
RGD
PMID:19580807
RGD:2317533
NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909
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Aqp1
aquaporin 1 (Colton blood group)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20018876
NCBI chrNW_004955410:32,066,196...32,078,661
Ensembl chrNW_004955410:32,066,196...32,078,717
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Bdkrb1
bradykinin receptor B1
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17988733 PMID:20152050
RGD:5129214
NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691
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Bdkrb2
bradykinin receptor B2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20152050
NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172
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Bdnf
brain derived neurotrophic factor
ISO
RGD
PMID:20452292
RGD:4891137
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
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Cacna2d1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17088553
NCBI chrNW_004955410:3,544,398...3,963,582
Ensembl chrNW_004955410:3,619,740...3,964,239
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Cck
cholecystokinin
ISO
RGD
PMID:17157334
RGD:2313635
NCBI chrNW_004955420:28,438,806...28,443,458
Ensembl chrNW_004955420:28,438,806...28,443,458
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Cckbr
cholecystokinin B receptor
ISO
associated with Diabetes Mellitus, Experimental
RGD
PMID:16527403
RGD:2311323
NCBI chrNW_004955414:22,001,351...22,011,275
Ensembl chrNW_004955414:22,000,436...22,011,433
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Ccl22
C-C motif chemokine ligand 22
ISO
RGD
PMID:11438578
RGD:2306307
NCBI chrNW_004955433:15,002,001...15,007,324
Ensembl chrNW_004955433:15,001,930...15,008,032
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Ccl5
C-C motif chemokine ligand 5
ISO
RGD
PMID:11438578
RGD:2306307
NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
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Ccr2
C-C motif chemokine receptor 2
ISO
associated with Osteoarthritis, Knee;
RGD
PMID:18419759 PMID:23185004
RGD:2307043 RGD:8661785
NCBI chrNW_004955420:25,641,184...25,664,413
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Clcn7
chloride voltage-gated channel 7
ISO
mRNA:increased expression:spinal cord dorsal horn
RGD
PMID:11846422
RGD:1600865
NCBI chrNW_004955442:15,762,369...15,791,635
Ensembl chrNW_004955442:15,761,498...15,791,635
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Cnr1
cannabinoid receptor 1
ISO
CTD Direct Evidence: therapeutic
RGD CTD
PMID:19193902 PMID:19661434
RGD:2314649
NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320
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Cnr2
cannabinoid receptor 2
ISO
RGD
PMID:19409856
RGD:2316193
NCBI chrNW_004955452:3,763,742...3,795,069
Ensembl chrNW_004955452:3,763,742...3,795,069
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Comt
catechol-O-methyltransferase
severity
ISO
CTD Direct Evidence: marker/mechanism associated with Multiple Sclerosis;DNA:polymorphism:cds:rs4680(p.V158M)(human)
CTD RGD
PMID:17084978 PMID:20561508 PMID:24290452
RGD:13450948 RGD:2289747
NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
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Crh
corticotropin releasing hormone
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16495007
NCBI chrNW_004955444:12,989,210...12,991,300
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Csf2
colony stimulating factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8622042
NCBI chrNW_004955408:3,452,009...3,454,255
Ensembl chrNW_004955408:3,451,965...3,454,312
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:7541186 PMID:8622042 PMID:10864982
NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
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Cx3cr1
C-X3-C motif chemokine receptor 1
ISO
associated with Bone Neoplasms
RGD
PMID:20736819
RGD:4892020
NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230
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Cxcl12
C-X-C motif chemokine ligand 12
ISO
RGD
PMID:11438578
RGD:2306307
NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690
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Disc1
DISC1 scaffold protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20561508
NCBI chrNW_004955492:6,946,528...7,239,328
Ensembl chrNW_004955492:6,953,389...7,239,328
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Drd2
dopamine receptor D2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15996639
NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
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Edn1
endothelin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19429182 PMID:20042899
NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
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Gch1
GTP cyclohydrolase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19081190
NCBI chrNW_004955409:8,624,225...8,670,436
Ensembl chrNW_004955409:8,624,468...8,668,614
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Gjb1
gap junction protein beta 1
ISO
ClinVar Annotator: match by term: Pain
ClinVar
PMID:16096811 PMID:21291455 PMID:22243284 PMID:25388846 PMID:25741868 PMID:26467025 PMID:28448691 PMID:28492532 More...
NCBI chrNW_004955475:10,779,415...10,787,910
Ensembl chrNW_004955475:10,785,996...10,787,910
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Gla
galactosidase alpha
treatment
ISO
compared to wild type Allyl isothiocyanate (XCO:0000608)
RGD
PMID:29563343
RGD:150429980
NCBI chrNW_004955503:7,526,077...7,535,817
Ensembl chrNW_004955503:7,521,930...7,535,817
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Grin1
glutamate ionotropic receptor NMDA type subunit 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:18155693
NCBI chrNW_004955513:5,154,864...5,178,636
Ensembl chrNW_004955513:5,154,864...5,178,636
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Hcrt
hypocretin neuropeptide precursor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16202530
NCBI chrNW_004955451:16,235,819...16,237,457
Ensembl chrNW_004955451:16,235,819...16,237,457
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Hfe
homeostatic iron regulator
ISO
ClinVar Annotator: match by term: Pain
ClinVar
PMID:678784 PMID:8696333 PMID:8896549 PMID:8896550 PMID:8931958 PMID:9024376 PMID:9138148 PMID:9162021 PMID:9211748 PMID:9321765 PMID:9326341 PMID:9328324 PMID:9341868 PMID:9356458 PMID:9439654 PMID:9462220 PMID:9482831 PMID:9585606 PMID:9851896 PMID:9851897 PMID:10381492 PMID:10401000 PMID:10431233 PMID:10575540 PMID:11040194 PMID:11532995 PMID:11812557 PMID:11903354 PMID:12241803 PMID:12429850 PMID:12436244 PMID:12542741 PMID:12693884 PMID:12707220 PMID:12915468 PMID:14618419 PMID:14729817 PMID:15060098 PMID:15070663 PMID:15254010 PMID:15280838 PMID:15347835 PMID:15858186 PMID:16132052 PMID:16879202 PMID:17389307 PMID:17450498 PMID:17828789 PMID:18199861 PMID:18499578 PMID:18504828 PMID:18566337 PMID:19084217 PMID:19159930 PMID:19429178 PMID:19444013 PMID:19554541 PMID:20301613 PMID:20471131 PMID:21243428 PMID:22531912 PMID:23178241 PMID:23953397 PMID:24033266 PMID:24604426 PMID:25457201 PMID:25728773 PMID:25741868 PMID:25741869 PMID:25850353 PMID:26153218 PMID:26365338 PMID:27124787 PMID:27518069 PMID:27659401 PMID:27890643 PMID:28492532 PMID:31061747 PMID:31436889 PMID:31980526 PMID:32153640 PMID:37260121 More...
NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
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Hgf
hepatocyte growth factor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:26000320
NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
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Hoxd1
homeobox D1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21151121
NCBI chrNW_004955403:20,476,813...20,478,604
Ensembl chrNW_004955403:20,476,645...20,478,604
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Hrh1
histamine receptor H1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12128009 PMID:14569158
NCBI chrNW_004955429:14,022,332...14,069,931
Ensembl chrNW_004955429:14,067,405...14,068,853
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Htr1a
5-hydroxytryptamine receptor 1A
ISO
CTD Direct Evidence: therapeutic
RGD CTD
PMID:12595749 PMID:21945716
RGD:5683627
NCBI chrNW_004955446:4,913,181...4,917,726
Ensembl chrNW_004955446:4,913,884...4,915,146
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Htr1b
5-hydroxytryptamine receptor 1B
ISO
RGD
PMID:16165284
RGD:1626470
NCBI chrNW_004955502:5,640,919...5,646,899
Ensembl chrNW_004955502:5,645,644...5,646,816
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Htr2c
5-hydroxytryptamine receptor 2C
ISO
RGD
PMID:17451674
RGD:1624996
NCBI chrNW_004955490:912,615...1,126,347
Ensembl chrNW_004955490:910,415...1,126,373
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Htr3b
5-hydroxytryptamine receptor 3B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17600820
NCBI chrNW_004955412:15,524,854...15,569,638
Ensembl chrNW_004955412:15,524,854...15,569,638
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Htr7
5-hydroxytryptamine receptor 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17600820
NCBI chrNW_004955425:2,321,420...2,420,420
Ensembl chrNW_004955425:2,321,420...2,420,530
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Il18
interleukin 18
ISO
RGD
PMID:19853379
RGD:2315887
NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634
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Il1rn
interleukin 1 receptor antagonist
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15317861
NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
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Il2
interleukin 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12421473
NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
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Il6st
interleukin 6 cytokine family signal transducer
ISO
RGD
PMID:20626857
RGD:5509945
NCBI chrNW_004955446:11,790,636...11,837,734
Ensembl chrNW_004955446:11,790,444...11,835,001
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Kng1
kininogen 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:1281941 PMID:3951883 PMID:10445233 PMID:10543429 PMID:16076651 PMID:20018876 PMID:29655911 More...
NCBI chrNW_004955420:20,989,197...21,016,084
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Map2k2
mitogen-activated protein kinase kinase 2
ISO
ClinVar Annotator: match by term: Pain
ClinVar
PMID:25741868 PMID:28492532
NCBI chrNW_004955495:4,695,239...4,718,380
Ensembl chrNW_004955495:4,695,768...4,722,098
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Ngf
nerve growth factor
treatment
ISO
associated with Cystitis, Interstitial
RGD
PMID:17905097 PMID:19103210
RGD:2303798 RGD:7242806
NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059
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Ngfr
nerve growth factor receptor
ISO
associated with Inflammation
RGD
PMID:20060234
RGD:5144063
NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305
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Nos3
nitric oxide synthase 3
ISO
RGD
PMID:18079061
RGD:2292111
NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
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Nppa
natriuretic peptide A
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:13679232
NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003
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Nppb
natriuretic peptide B
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27687165
NCBI chrNW_004955486:2,054,775...2,056,130
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Npr1
natriuretic peptide receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27687165
NCBI chrNW_004955545:323,386...338,654
Ensembl chrNW_004955545:323,956...338,097
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Nrg1
neuregulin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20561508
NCBI chrNW_004955463:8,009,436...9,037,116
Ensembl chrNW_004955463:8,009,530...9,037,116
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Ntsr1
neurotensin receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20727387
NCBI chrNW_004955528:1,348,616...1,394,798
Ensembl chrNW_004955528:1,348,555...1,394,868
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Oprd1
opioid receptor delta 1
ISO
RGD
PMID:12710986
RGD:2316589
NCBI chrNW_004955452:7,866,790...7,913,399
Ensembl chrNW_004955452:7,866,758...7,913,399
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Oprk1
opioid receptor kappa 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9463367
NCBI chrNW_004955454:12,741,577...12,751,282
Ensembl chrNW_004955454:12,744,765...12,752,226
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Oprm1
opioid receptor mu 1
ISO
RGD
PMID:12710986
RGD:2316589
NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817
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Pdyn
prodynorphin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17670969 PMID:20068450
NCBI chrNW_004955415:13,106,087...13,119,497
Ensembl chrNW_004955415:13,106,062...13,119,515
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Penk
proenkephalin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15833551
NCBI chrNW_004955454:15,425,712...15,426,685
Ensembl chrNW_004955454:15,426,017...15,426,685
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Plcb1
phospholipase C beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16405873
NCBI chrNW_004955415:18,210,608...18,915,099
Ensembl chrNW_004955415:18,210,662...18,915,158
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Pnoc
prepronociceptin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:19231294
NCBI chrNW_004955403:50,735,567...50,755,892
Ensembl chrNW_004955403:50,735,390...50,755,902
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Pomc
proopiomelanocortin
ISO
CTD Direct Evidence: marker/mechanism|therapeutic associated with Inflammation
CTD RGD
PMID:4345333 PMID:6094376 PMID:17223201 PMID:20084599
RGD:407574731
NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
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Pparg
peroxisome proliferator activated receptor gamma
ISO
RGD
PMID:18387855
RGD:2301890
NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
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Ppp1r9a
protein phosphatase 1 regulatory subunit 9A
treatment
ISO
RGD
PMID:20359166
RGD:10002735
NCBI chrNW_004955432:11,607,269...11,891,568
Ensembl chrNW_004955432:11,608,382...11,886,044
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Prkg1
protein kinase cGMP-dependent 1
ISO
protein:increased expression:spinal cord
RGD
PMID:12384231
RGD:7775057
NCBI chrNW_004955425:6,176,335...7,335,867
Ensembl chrNW_004955425:6,176,432...7,331,446
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Prokr1
prokineticin receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16793879
NCBI chrNW_004955424:16,287,666...16,301,713
Ensembl chrNW_004955424:16,287,653...16,301,713
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Ptgs1
prostaglandin-endoperoxide synthase 1
ISO
associated with Osteoarthritis, Knee;mRNA, protein:increased expression:spinal cord
RGD
PMID:17942724 PMID:18637715
RGD:2300223 RGD:2300252
NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305
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Ptgs2
prostaglandin-endoperoxide synthase 2
susceptibility
ISO
associated with Osteoarthritis, Knee;mRNA, protein:increased expression:spinal cord associated with lung neoplasm;DNA:SNP:exon:rs5275 (human)
RGD
PMID:18497304 PMID:18637715 PMID:19773451
RGD:2300223 RGD:2300228 RGD:5135482
NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
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Ptn
pleiotrophin
severity
ISO
RGD
PMID:20826137
RGD:10043829
NCBI chrNW_004955494:5,580,264...5,681,848
Ensembl chrNW_004955494:5,580,422...5,684,190
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Slc6a1
solute carrier family 6 member 1
ISO
RGD
PMID:17918738
RGD:1643217
NCBI chrNW_004955429:13,930,899...13,946,010
Ensembl chrNW_004955429:13,930,905...13,947,389
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Slc9a1
solute carrier family 9 member A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19248819
NCBI chrNW_004955452:6,409,833...6,467,841
Ensembl chrNW_004955452:6,409,833...6,467,841
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Tac1
tachykinin precursor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:7694222 PMID:10445233 PMID:17493276
RGD:2304337
NCBI chrNW_004955432:13,991,647...13,999,665
Ensembl chrNW_004955432:13,991,414...13,999,728
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Tacr1
tachykinin receptor 1
ISO
RGD
PMID:18407414
RGD:2304276
NCBI chrNW_004955424:10,614,340...10,761,872
Ensembl chrNW_004955424:10,614,340...10,761,872
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Tacr3
tachykinin receptor 3
ISO
RGD
PMID:19093101
RGD:2304256
NCBI chrNW_004955496:5,152,134...5,222,565
Ensembl chrNW_004955496:5,151,668...5,222,624
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Tjp1
tight junction protein 1
ISO
associated with Inflammation;protein:increased expression:brain
RGD
PMID:19319146
RGD:2325136
NCBI chrNW_004955416:28,640,807...28,869,717
Ensembl chrNW_004955416:28,654,905...28,870,555
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Tlr2
toll like receptor 2
ISO
RGD
PMID:24204973
RGD:8553185
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
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Tlr4
toll like receptor 4
ISO
RGD
PMID:18662331
RGD:2312574
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18582539 PMID:20383154
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
protein:increased expression:dorsal root ganglion (rat)
RGD
PMID:21248590
RGD:5130897
NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
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Trh
thyrotropin releasing hormone
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:6409194
NCBI chrNW_004955429:17,487,275...17,489,385
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Trpa1
transient receptor potential cation channel subfamily A member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20601631
NCBI chrNW_004955444:7,876,284...7,922,010
Ensembl chrNW_004955444:7,876,429...7,921,372
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Trpv1
transient receptor potential cation channel subfamily V member 1
treatment
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:16996476 PMID:17575321 PMID:20422007 PMID:22998799 PMID:23006841
RGD:597976450
NCBI chrNW_004955467:13,221,391...13,239,089
Ensembl chrNW_004955467:13,221,391...13,239,089
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Vip
vasoactive intestinal peptide
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:9920454
NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792
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Hfe
homeostatic iron regulator
ISO
ClinVar Annotator: match by term: Abdominal pain
ClinVar
PMID:678784 PMID:8696333 PMID:8896549 PMID:8896550 PMID:8931958 PMID:9024376 PMID:9138148 PMID:9162021 PMID:9211748 PMID:9321765 PMID:9326341 PMID:9328324 PMID:9341868 PMID:9356458 PMID:9439654 PMID:9462220 PMID:9482831 PMID:9585606 PMID:9851896 PMID:9851897 PMID:10381492 PMID:10401000 PMID:10431233 PMID:10575540 PMID:11040194 PMID:11532995 PMID:11812557 PMID:11903354 PMID:12241803 PMID:12429850 PMID:12436244 PMID:12542741 PMID:12693884 PMID:12707220 PMID:12915468 PMID:14618419 PMID:14729817 PMID:15060098 PMID:15070663 PMID:15254010 PMID:15280838 PMID:15347835 PMID:15858186 PMID:16132052 PMID:16879202 PMID:17389307 PMID:17450498 PMID:17828789 PMID:18199861 PMID:18499578 PMID:18504828 PMID:18566337 PMID:19084217 PMID:19159930 PMID:19429178 PMID:19444013 PMID:19554541 PMID:20301613 PMID:20471131 PMID:21243428 PMID:22531912 PMID:23178241 PMID:23953397 PMID:24033266 PMID:24604426 PMID:25457201 PMID:25728773 PMID:25741868 PMID:25741869 PMID:25850353 PMID:26153218 PMID:26365338 PMID:27124787 PMID:27518069 PMID:27659401 PMID:27890643 PMID:28492532 PMID:31061747 PMID:31436889 PMID:31980526 PMID:32153640 PMID:37260121 More...
NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
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Hmbs
hydroxymethylbilane synthase
ISO
ClinVar Annotator: match by term: Abdominal pain
ClinVar
NCBI chrNW_004955412:20,192,519...20,202,635
Ensembl chrNW_004955412:20,192,522...20,202,635
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Trpa1
transient receptor potential cation channel subfamily A member 1
ISO
RGD
PMID:24291101
RGD:10043376
NCBI chrNW_004955444:7,876,284...7,922,010
Ensembl chrNW_004955444:7,876,429...7,921,372
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Comt
catechol-O-methyltransferase
susceptibility
ISO
associated with Anemia, Sickle Cell;DNA:polymorphism:cds:p.V158M(human)
RGD
PMID:25102390
RGD:13450943
NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
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Septin9
septin 9
ISO
ClinVar Annotator: match by term: Amyotrophic neuralgia | ClinVar Annotator: match by term: Amyotrophy, hereditary neuralgic | ClinVar Annotator: match by term: Hereditary Neuralgic Amyotrophy (HNA)
ClinVar
PMID:16186812 PMID:17546647 PMID:18492087 PMID:19139049 PMID:19204161 PMID:19451530 PMID:20019224 PMID:20301569 PMID:22981636 PMID:25741868 PMID:26467025 PMID:28492532 PMID:28503616 PMID:31619932 More...
NCBI chrNW_004955506:4,943,108...5,033,088
Ensembl chrNW_004955506:4,942,056...5,090,441
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Adrb1
adrenoceptor beta 1
ISO
RGD
PMID:11527135
RGD:5129114
NCBI chrNW_004955431:19,025,663...19,027,026
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Adrb2
adrenoceptor beta 2
ISO
RGD
PMID:11527135
RGD:5129114
NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980
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Cpb2
carboxypeptidase B2
ISO
RGD
PMID:12624641
RGD:1598479
NCBI chrNW_004955518:3,740,348...3,803,540
Ensembl chrNW_004955518:3,740,348...3,803,539
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Plau
plasminogen activator, urokinase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:1730212
NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209
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Spp1
secreted phosphoprotein 1
ISO
RGD
PMID:16421174
RGD:1581390
NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016
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Bdnf
brain derived neurotrophic factor
treatment
ISO
associated with osteoarthritis
RGD
PMID:31479064
RGD:597015765
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:7543699
NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
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Mvk
mevalonate kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:10369261
NCBI chrNW_004955455:8,933,250...8,953,883
Ensembl chrNW_004955455:8,930,125...8,953,894
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Tsc2
TSC complex subunit 2
ISO
ClinVar Annotator: match by term: Arthralgia
ClinVar
PMID:25741868 PMID:28492532 PMID:30311386
NCBI chrNW_004955442:15,178,356...15,216,978
Ensembl chrNW_004955442:15,178,487...15,216,362
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Wnt10a
Wnt family member 10A
ISO
ClinVar Annotator: match by term: Arthralgias
ClinVar
PMID:24449199 PMID:28492532
NCBI chrNW_004955453:14,528,373...14,540,801
Ensembl chrNW_004955453:14,528,153...14,540,818
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Htr2a
5-hydroxytryptamine receptor 2A
ISO
RGD
PMID:17268262
RGD:1624379
NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345
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Plat
plasminogen activator, tissue type
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12227717
NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
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Cxcr4
C-X-C motif chemokine receptor 4
ISO
mRNA,protein:increased expression:spinal cord:
RGD
PMID:28108674 PMID:28638088
RGD:13463594 RGD:13838657
NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109
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Dlg4
discs large MAGUK scaffold protein 4
ameliorates
ISO
RGD
PMID:26738857
RGD:243048441
NCBI chrNW_004955467:9,691,733...9,715,872
Ensembl chrNW_004955467:9,690,469...9,715,872
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Jak2
Janus kinase 2
treatment
ISO
RGD
PMID:30027795
RGD:149735350
NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
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Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
ISO
mRNA, protein:increased expression:spinal cord (rat)
RGD
PMID:25919859
RGD:152025537
NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422
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Robo1
roundabout guidance receptor 1
exacerbates
ISO
RGD
PMID:26738857
RGD:243048441
NCBI chrNW_004955407:12,593,911...13,485,723
Ensembl chrNW_004955407:13,107,235...13,487,053
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Slit2
slit guidance ligand 2
ameliorates
ISO
RGD
PMID:26738857
RGD:243048441
NCBI chrNW_004955480:3,982,977...4,314,160
Ensembl chrNW_004955480:3,984,586...4,313,908
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Crh
corticotropin releasing hormone
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:2563132
NCBI chrNW_004955444:12,989,210...12,991,300
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Bdnf
brain derived neurotrophic factor
ISO
protein:increased expression:frontal cortex, neuron mRNA:decreased expression:anterior cingulate cortex
RGD
PMID:11360665 PMID:24518228
RGD:10059366 RGD:5684922
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
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Cpt2
carnitine palmitoyltransferase 2
ISO
ClinVar Annotator: match by term: Chronic pain
ClinVar
PMID:7711730 PMID:9600456 PMID:10090476 PMID:12410208 PMID:12673791 PMID:12707442 PMID:15622536 PMID:16996287 PMID:17936304 PMID:20301431 PMID:22975760 PMID:25741868 PMID:28492532 PMID:34063237 More...
NCBI chrNW_004955464:5,942,986...5,970,325
Ensembl chrNW_004955464:5,942,986...5,970,345
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Hfe
homeostatic iron regulator
ISO
DNA:missense mutation: :p.C282Y (rs1800562) (human)
RGD
PMID:30657865
RGD:14746966
NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
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Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
protein:increased expression:frontal cortex, neuron
RGD
PMID:11360665
RGD:5684922
NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
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Scn9a
sodium voltage-gated channel alpha subunit 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21634377
NCBI chrNW_004955449:7,858,156...8,017,569
Ensembl chrNW_004955449:7,923,801...8,017,569
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Tlr2
toll like receptor 2
ISO
RGD
PMID:24204973
RGD:8553185
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
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Tlr4
toll like receptor 4
ISO
RGD
PMID:24204973
RGD:8553185
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Dnmt3b
DNA methyltransferase 3 beta
ISO
protein:increased expression:ectopic endometrium:
RGD
PMID:22572543
RGD:9588664
NCBI chrNW_004955422:28,380,595...28,427,012
Ensembl chrNW_004955422:28,380,591...28,421,301
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Dmd
dystrophin
ISO
ClinVar Annotator: match by term: Exertional myalgia, muscle stiffness and myoglobinuria
ClinVar
PMID:19367636 PMID:21104870 PMID:25637381 PMID:25741868 PMID:26066469 PMID:26365249 PMID:26467025 PMID:28492532 PMID:31648988 PMID:33146414 PMID:33644936 PMID:35135626 PMID:36409343 More...
NCBI chrNW_004955535:1,283,084...3,297,015
Ensembl chrNW_004955535:1,283,523...3,299,542
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Pomc
proopiomelanocortin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:4327920
NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
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Trpa1
transient receptor potential cation channel subfamily A member 1
ISO
ClinVar Annotator: match by term: Familial episodic pain syndrome 1 | ClinVar Annotator: match by term: TRPA1-related condition
OMIM ClinVar
PMID:20547126 PMID:25741868 PMID:36430572
NCBI chrNW_004955444:7,876,284...7,922,010
Ensembl chrNW_004955444:7,876,429...7,921,372
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Scn10a
sodium voltage-gated channel alpha subunit 10
ISO
ClinVar Annotator: match by term: Episodic pain syndrome, familial, 2
OMIM ClinVar
PMID:9536098 PMID:17576681 PMID:23115331 PMID:24820863 PMID:24998131 PMID:25053638 PMID:25691538 PMID:25691686 PMID:25741868 PMID:25842276 PMID:26220970 PMID:26423924 PMID:26733327 PMID:27711072 PMID:28074886 PMID:28078312 PMID:28407228 PMID:28492532 PMID:29247119 PMID:29874177 PMID:29911575 PMID:30135145 PMID:30403391 PMID:30554136 PMID:30662450 PMID:30821013 PMID:31195250 PMID:31780880 PMID:31928344 PMID:32581362 PMID:32917565 PMID:32948286 PMID:36895957 PMID:37993639 More...
NCBI chrNW_004955427:25,157,179...25,244,020
Ensembl chrNW_004955427:25,157,179...25,243,473
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Scn11a
sodium voltage-gated channel alpha subunit 11
ISO
ClinVar Annotator: match by term: Episodic pain syndrome, familial, 3
OMIM ClinVar
PMID:9536098 PMID:17576681 PMID:24207120 PMID:24776970 PMID:25741868 PMID:25791876 PMID:27224030 PMID:27503742 PMID:28298626 PMID:28492532 PMID:30046661 PMID:30554136 PMID:30557356 More...
NCBI chrNW_004955427:24,917,709...25,109,499
Ensembl chrNW_004955427:24,989,615...25,109,550
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:10864982
NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
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Fkrp
fukutin related protein
ISO
ClinVar Annotator: match by term: Headache
ClinVar
PMID:11741828 PMID:12666124 PMID:14647208 PMID:15060126 PMID:15574464 PMID:15580560 PMID:15833432 PMID:15883334 PMID:15886712 PMID:16344347 PMID:16634037 PMID:16786213 PMID:17554798 PMID:18060779 PMID:18593008 PMID:18639457 PMID:19705481 PMID:19820980 PMID:19835634 PMID:19900540 PMID:20961759 PMID:21220724 PMID:21228398 PMID:22264518 PMID:22981120 PMID:23576288 PMID:23591631 PMID:24447024 PMID:25048216 PMID:25560911 PMID:25741868 PMID:26363967 PMID:26467025 PMID:26574668 PMID:26833294 PMID:28112097 PMID:28479227 PMID:28492532 PMID:30232282 PMID:30564623 PMID:30919934 PMID:31268217 PMID:32914449 PMID:34008892 PMID:34653404 More...
NCBI chrNW_004955574:779,672...789,621
Ensembl chrNW_004955574:786,758...788,348
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Gnrh1
gonadotropin releasing hormone 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12910066
NCBI chrNW_004955403:48,341,731...48,346,595
Ensembl chrNW_004955403:48,343,597...48,346,595
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Il6
interleukin 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:7537110
NCBI chrNW_004955410:25,079,835...25,084,390
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Npc1
NPC intracellular cholesterol transporter 1
ISO
ClinVar Annotator: match by term: Headache
ClinVar
PMID:10521290 PMID:11333381 PMID:11349231 PMID:11479732 PMID:11754101 PMID:12401890 PMID:12955717 PMID:14639697 PMID:15937921 PMID:16098014 PMID:20301473 PMID:20554533 PMID:23183285 PMID:23427322 PMID:23773996 PMID:23791518 PMID:25236789 PMID:25349751 PMID:25425405 PMID:25741868 PMID:26666848 PMID:26981555 PMID:28492532 PMID:32138288 PMID:32248828 PMID:39825153 More...
NCBI chrNW_004955402:11,699,434...11,742,899
Ensembl chrNW_004955402:11,699,434...11,742,899
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Tnfrsf1b
TNF receptor superfamily member 1B
ISO
human protein in rat model
RGD
PMID:21036476
RGD:5131274
NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362
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Wfs1
wolframin ER transmembrane glycoprotein
ISO
DNA:missense mutation: :p.H611R (human)
RGD
PMID:17719176
RGD:8694403
NCBI chrNW_004955514:3,902,508...3,924,281
Ensembl chrNW_004955514:3,902,454...3,924,610
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Abat
4-aminobutyrate aminotransferase
treatment
ISO
RGD
PMID:24890317
RGD:9588557
NCBI chrNW_004955442:9,422,849...9,516,054
Ensembl chrNW_004955442:9,422,849...9,516,103
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Adk
adenosine kinase
ISO
associated with diabetic neuropathies;
RGD
PMID:9932716 PMID:11423084
RGD:6482662 RGD:6482666
NCBI chrNW_004955437:17,279,541...17,786,140
Ensembl chrNW_004955437:17,279,240...17,786,079
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Adm
adrenomedullin
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17043245
RGD:1625316
NCBI chrNW_004955414:25,951,473...25,953,593
Ensembl chrNW_004955414:25,951,349...25,953,645
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Adora1
adenosine A1 receptor
ISO
associated with Spinal Cord Injuries
RGD
PMID:20065990
RGD:5129094
NCBI chrNW_004955406:39,148,811...39,183,577
Ensembl chrNW_004955406:39,149,689...39,187,688
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Adra1a
adrenoceptor alpha 1A
ISO
associated with Diabetes Mellitus, Experimental; mRNA:increased expression:dorsal root ganglion
RGD
PMID:10841349
RGD:5688377
NCBI chrNW_004955403:49,394,173...49,485,881
Ensembl chrNW_004955403:49,399,127...49,485,934
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Adra2a
adrenoceptor alpha 2A
ISO
RGD
PMID:17959985
RGD:6480488
NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240
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Adrb1
adrenoceptor beta 1
ISO
RGD
PMID:19283893
RGD:5129125
NCBI chrNW_004955431:19,025,663...19,027,026
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Ager
advanced glycosylation end-product specific receptor
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:24077211 PMID:25014009
RGD:7364865 RGD:8695980
NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
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Agt
angiotensinogen
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9613798
NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
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Aif1
allograft inflammatory factor 1
ISO
associated with Alcohol-Induced Disorders, Nervous System; protein:increased expression:spinal cord (rat) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17284346 PMID:27093858
RGD:2313035
NCBI chrNW_004955437:157,509...158,919
Ensembl chrNW_004955437:157,509...158,919
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Alox5
arachidonate 5-lipoxygenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12582831
NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909
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Ano3
anoctamin 3
ISO
RGD
PMID:23872594
RGD:9681745
NCBI chrNW_004955476:5,702,888...6,060,545
Ensembl chrNW_004955476:5,813,071...6,060,545
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Anxa1
annexin A1
ISO
protein:increased expression:dorsal root ganglion
RGD
PMID:9222544 PMID:21990306
RGD:2306950 RGD:7421656
NCBI chrNW_004955512:5,686,508...5,703,645
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Aqp4
aquaporin 4
ISO
associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord:
RGD
PMID:16219025
RGD:8695957
NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709
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Bace1
beta-secretase 1
ISO
RGD
PMID:28012171
RGD:13782150
NCBI chrNW_004955412:18,596,643...18,620,089
Ensembl chrNW_004955412:18,596,643...18,620,362
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Bdkrb1
bradykinin receptor B1
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:12637034 PMID:12927641 PMID:17989505 PMID:19300402 PMID:19815945
RGD:1579989 RGD:7241581
NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691
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Bdkrb2
bradykinin receptor B2
ISO
CTD Direct Evidence: marker/mechanism associated with Diabetic Neuropathy
RGD CTD
PMID:10188975 PMID:17989505 PMID:19300402 PMID:19815945
RGD:2313332 RGD:4891040
NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172
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Bdnf
brain derived neurotrophic factor
ISO
associated with Sciatic Neuropathy; associated with Peripheral Nerve Injuries; associated with Pancreatitis, Chronic; associated with inflammation;protein:increased expression:dorsal root ganglion:
RGD
PMID:10779676 PMID:11425916 PMID:12435470 PMID:12470870 PMID:21499209 PMID:21864655 PMID:21958434 More...
RGD:8657088 RGD:8657091 RGD:8657093 RGD:8657099 RGD:8657101 RGD:8657114 RGD:8657122
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
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Becn1
beclin 1
ISO
RGD
PMID:23665054
RGD:11560531
NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
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C3
complement C3
ISO
associated with Sciatic Neuropathy;mRNA, protein:increased expression:spinal cord
RGD
PMID:23588254
RGD:7401259
NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
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Cacna1b
calcium voltage-gated channel subunit alpha1 B
ISO
RGD
PMID:17567797
RGD:1626313
NCBI chrNW_004955513:5,654,915...5,823,094
Ensembl chrNW_004955513:5,654,238...5,824,386
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Cacna1h
calcium voltage-gated channel subunit alpha1 H
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19577366 PMID:30552955 PMID:34286406
NCBI chrNW_004955442:16,047,965...16,108,862
Ensembl chrNW_004955442:16,045,895...16,108,862
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Cacna1i
calcium voltage-gated channel subunit alpha1 I
ISO
RGD
PMID:17112407
RGD:15003199
NCBI chrNW_004955413:25,440,533...25,538,367
Ensembl chrNW_004955413:25,453,703...25,535,530
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Cacna2d1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11245671 PMID:17881535 PMID:24133248
NCBI chrNW_004955410:3,544,398...3,963,582
Ensembl chrNW_004955410:3,619,740...3,964,239
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Camk2a
calcium/calmodulin dependent protein kinase II alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18042863 PMID:20053885
RGD:7240711
NCBI chrNW_004955415:4,247,307...4,307,402
Ensembl chrNW_004955415:4,247,014...4,307,458
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Capn2
calpain 2
treatment
ISO
associated with Peripheral Nerve Injuries
RGD
PMID:25150005
RGD:13792585
NCBI chrNW_004955520:1,287,829...1,315,318
Ensembl chrNW_004955520:1,286,356...1,315,328
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Cartpt
CART prepropeptide
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21167239
NCBI chrNW_004955575:551,991...555,118
Ensembl chrNW_004955575:551,991...555,149
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Cat
catalase
treatment
ISO
RGD
PMID:23658840 PMID:23952340
RGD:9479063 RGD:9479069
NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
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Cck
cholecystokinin
ISO
RGD
PMID:15647484
RGD:1626108
NCBI chrNW_004955420:28,438,806...28,443,458
Ensembl chrNW_004955420:28,438,806...28,443,458
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Cckbr
cholecystokinin B receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:11880531 PMID:15647484
RGD:1626108
NCBI chrNW_004955414:22,001,351...22,011,275
Ensembl chrNW_004955414:22,000,436...22,011,433
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Ccl5
C-C motif chemokine ligand 5
ISO
mRNA:increased expression:dorsal root ganglion (rat)
RGD
PMID:18076762 PMID:18656466
RGD:2303121 RGD:4890034
NCBI chrNW_004955481:10,293,758...10,301,118
Ensembl chrNW_004955481:10,293,399...10,301,143
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Ccr2
C-C motif chemokine receptor 2
ISO
associated with Sciatic Neuropathy; protein:increased expression:dorsal horn of spinal cord: associated with Intervertebral disc disease; associated with Demyelinating Diseases; associated with Bone Neoplasms;protein:increased expression:spinal cord:
RGD
PMID:18076762 PMID:18419759 PMID:22721162 PMID:23511129 PMID:24462503 PMID:24907405 More...
RGD:2307043 RGD:4890034 RGD:8548831 RGD:8661772 RGD:8661781 RGD:8661788
NCBI chrNW_004955420:25,641,184...25,664,413
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Cfl1
cofilin 1
ISO
protein:increased phosphorylation:dorsal root ganglion (rat)
RGD
PMID:24962708
RGD:11570412
NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
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Chrna5
cholinergic receptor nicotinic alpha 5 subunit
ameliorates
ISO
RGD
PMID:15652389
RGD:150530460
NCBI chrNW_004955450:945,400...974,129
Ensembl chrNW_004955450:946,898...974,457
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Chrna7
cholinergic receptor nicotinic alpha 7 subunit
ameliorates
ISO
associated with sciatic neuropathy;
RGD
PMID:20619541
RGD:151708701
NCBI chrNW_004955416:30,687,518...30,798,700
Ensembl chrNW_004955416:30,687,478...30,798,700
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Cnr1
cannabinoid receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17572696
NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320
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Cnr2
cannabinoid receptor 2
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:17572696 PMID:18664590
NCBI chrNW_004955452:3,763,742...3,795,069
Ensembl chrNW_004955452:3,763,742...3,795,069
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Comt
catechol-O-methyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20726980 PMID:28195063
RGD:8662326
NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
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Crcp
CGRP receptor component
ISO
RGD
PMID:12895509
RGD:727768
NCBI chrNW_004955456:8,431,161...8,479,866
Ensembl chrNW_004955456:8,431,161...8,483,181
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Crhr1
corticotropin releasing hormone receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28434951
NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825
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Csf3
colony stimulating factor 3
treatment
ISO
associated with Sciatic Neuropathy;
RGD
PMID:24253780
RGD:11039470
NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
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Csk
C-terminal Src kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16769263
NCBI chrNW_004955450:3,127,561...3,144,550
Ensembl chrNW_004955450:3,127,561...3,144,550
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Ctss
cathepsin S
ISO
associated with Colitis associated with Arthritis, Experimental
RGD
PMID:21802389 PMID:22213084
RGD:5686870 RGD:5686873
NCBI chrNW_004955413:99,279...124,793
Ensembl chrNW_004955413:99,159...124,042
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Cx3cl1
C-X3-C motif chemokine ligand 1
treatment
ISO
associated with Arthritis, Experimental
RGD
PMID:19249394 PMID:22647647
RGD:2304251 RGD:9491779
NCBI chrNW_004955433:15,023,272...15,034,650
Ensembl chrNW_004955433:15,023,050...15,034,711
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Cx3cr1
C-X3-C motif chemokine receptor 1
ISO
associated with Sciatic Neuropathy associated with Bone Neoplasms associated with Inflammation associated with Arthritis, Experimental;protein:increased expression:lumbar spinal cord
RGD
PMID:16324111 PMID:19959384 PMID:20524966 PMID:20609517 PMID:20736819 PMID:22647647 More...
RGD:4891885 RGD:4891942 RGD:4892020 RGD:9354422 RGD:9387859 RGD:9491779
NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230
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Cxcl12
C-X-C motif chemokine ligand 12
ISO
RGD
PMID:28638088
RGD:13838657
NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690
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Cxcl8
C-X-C motif chemokine ligand 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:7881729 PMID:10401557
NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
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Cxcr4
C-X-C motif chemokine receptor 4
treatment
ISO
RGD
PMID:28638088 PMID:30142543
RGD:13838657 RGD:13838658
NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109
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Cybb
cytochrome b-245 beta chain
ISO
associated with Spinal Cord Injuries;
RGD
PMID:20679217
RGD:11040629
NCBI chrNW_004955587:781,533...818,149
Ensembl chrNW_004955587:781,388...819,912
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Dlg4
discs large MAGUK scaffold protein 4
ISO
associated with Diabetic neuropathies;
RGD
PMID:20531396
RGD:7257680
NCBI chrNW_004955467:9,691,733...9,715,872
Ensembl chrNW_004955467:9,690,469...9,715,872
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Drd3
dopamine receptor D3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20433900
NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178
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Dusp1
dual specificity phosphatase 1
treatment
ISO
associated with Sciatic Neuropathy
RGD
PMID:22540262 PMID:22901764
RGD:7771531 RGD:7771574
NCBI chrNW_004955408:25,481,294...25,484,381
Ensembl chrNW_004955408:25,481,294...25,484,381
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Dusp6
dual specificity phosphatase 6
treatment
ISO
associated with Sciatic Neuropathy
RGD
PMID:22901764
RGD:7771531
NCBI chrNW_004955405:26,662,018...26,666,314
Ensembl chrNW_004955405:26,662,018...26,666,314
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Edn1
endothelin 1
susceptibility
ISO
mRNA:increased expression:paw skin (mouse) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:15664691 PMID:19429182 PMID:23347081
RGD:8661716 RGD:8661735
NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
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Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
treatment
ISO
RGD
PMID:20392816
RGD:9685429
NCBI chrNW_004955417:25,308,424...25,384,307
Ensembl chrNW_004955417:25,308,361...25,384,443
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Ep300
E1A binding protein p300
ISO
RGD
PMID:25263804
RGD:9588307
NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933
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Epha4
EPH receptor A4
ISO
associated with spinal cord injuries;
RGD
PMID:16959251
RGD:5688783
NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199
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Ephx2
epoxide hydrolase 2
ISO
RGD
PMID:16962614
RGD:5688387
NCBI chrNW_004955403:49,999,563...50,038,800
Ensembl chrNW_004955403:49,999,563...50,041,572
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Erbb4
erb-b2 receptor tyrosine kinase 4
ISO
associated with interstitial cystitis;
RGD
PMID:30989724
RGD:405295490
NCBI chrNW_004955457:3,177,905...4,236,152
Ensembl chrNW_004955457:3,177,991...4,228,558
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Esr1
estrogen receptor 1
ISO
RGD
PMID:19285805
RGD:8553066
NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
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Esr2
estrogen receptor 2
ISO
RGD
PMID:17056036 PMID:19285805
RGD:5508846 RGD:8553066
NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
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F2
coagulation factor II, thrombin
ISO
associated with Sciatic Neuropathy
RGD
PMID:16251448
RGD:7387272
NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
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F2r
coagulation factor II thrombin receptor
severity
ISO
RGD
PMID:11877315 PMID:12717003 PMID:19674841
RGD:7387269 RGD:7387270 RGD:7387271
NCBI chrNW_004955425:24,144,905...24,164,498
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:dorsal horn of spinal cord, neuron
CTD RGD
PMID:22160634 PMID:27093858
RGD:9999169
NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728
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Fto
FTO alpha-ketoglutarate dependent dioxygenase
treatment
ISO
associated with Cerebral Hemorrhage
RGD
PMID:34102854
RGD:329812008
NCBI chrNW_004955433:11,424,069...11,834,955
Ensembl chrNW_004955433:11,424,176...11,813,771
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Gad1
glutamate decarboxylase 1
treatment
ISO
protein:increased expression:dorsal horn of spinal cord
RGD
PMID:26752351 PMID:27277808
RGD:405850208 RGD:405850240
NCBI chrNW_004955449:3,964,006...4,001,850
Ensembl chrNW_004955449:3,963,705...4,001,850
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Gal
galanin and GMAP prepropeptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12787826
NCBI chrNW_004955422:17,202,770...17,207,948
Ensembl chrNW_004955422:17,202,946...17,207,948
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Gdnf
glial cell derived neurotrophic factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20457222
NCBI chrNW_004955426:22,386,613...22,412,324
Ensembl chrNW_004955426:22,386,450...22,412,324
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Gfap
glial fibrillary acidic protein
ISO
associated with Spinal Cord Injuries;mRNA,protein:increased expression:brain,spinal cord: CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16219025 PMID:27093858
RGD:8695957
NCBI chrNW_004955451:17,695,835...17,703,894
Ensembl chrNW_004955451:17,695,835...17,703,268
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Gfra1
GDNF family receptor alpha 1
ISO
RGD
PMID:16464682
RGD:6218969
NCBI chrNW_004955431:20,859,152...21,070,886
Ensembl chrNW_004955431:20,866,685...21,070,853
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Gja1
gap junction protein alpha 1
treatment
ISO
CTD Direct Evidence: marker/mechanism associated with Sciatic Neuropathy
RGD CTD
PMID:23374942 PMID:24631560 PMID:34286406
RGD:8662447 RGD:8662456
NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095
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Gper1
G protein-coupled estrogen receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:25280432
NCBI chrNW_004955460:8,790,798...8,794,902
Ensembl chrNW_004955460:8,790,798...8,794,902
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Gria1
glutamate ionotropic receptor AMPA type subunit 1
treatment
ISO
RGD
PMID:27816787
RGD:405650587
NCBI chrNW_004955408:7,912,223...8,226,241
Ensembl chrNW_004955408:7,912,592...8,223,570
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Grin1
glutamate ionotropic receptor NMDA type subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27093858
NCBI chrNW_004955513:5,154,864...5,178,636
Ensembl chrNW_004955513:5,154,864...5,178,636
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
ISO
RGD
PMID:29758384
RGD:13792698
NCBI chrNW_004955442:8,171,114...8,565,187
Ensembl chrNW_004955442:8,174,232...8,562,059
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:20042082 PMID:24204988
RGD:13210755
NCBI chrNW_004955413:10,358,931...10,780,004
Ensembl chrNW_004955413:10,376,597...10,779,145
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Grk2
G protein-coupled receptor kinase 2
treatment severity
ISO
associated with Complex Regional Pain Syndromes associated with bone cancer
RGD
PMID:22796071 PMID:25466829 PMID:26064176 PMID:26935064
RGD:13513996 RGD:13514046 RGD:13514049 RGD:13792780
NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412
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Grm8
glutamate metabotropic receptor 8
ISO
RGD
PMID:17113112
RGD:6771186
NCBI chrNW_004955479:7,520,537...8,279,942
Ensembl chrNW_004955479:7,520,396...8,279,755
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Hif1a
hypoxia inducible factor 1 subunit alpha
ISO
associated with Limb Ischemia;protein:increased expression:foot muscle, plantar
RGD
PMID:18691814
RGD:9068903
NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
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Hmgb1
high mobility group box 1
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:24077211 PMID:27474498 PMID:30142543
RGD:13838658 RGD:7364865
NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
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Hoxd1
homeobox D1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21151121
NCBI chrNW_004955403:20,476,813...20,478,604
Ensembl chrNW_004955403:20,476,645...20,478,604
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Htr2a
5-hydroxytryptamine receptor 2A
ISO
associated with Diabetic neuropathies; CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17888573 PMID:18930597 PMID:20039957 PMID:20531396 PMID:25584948
RGD:401901200 RGD:401938625 RGD:7257680
NCBI chrNW_004955431:583,165...646,991
Ensembl chrNW_004955431:580,713...647,345
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Htr7
5-hydroxytryptamine receptor 7
ISO
RGD
PMID:21693130 PMID:21843960
RGD:6480665 RGD:6482179
NCBI chrNW_004955425:2,321,420...2,420,420
Ensembl chrNW_004955425:2,321,420...2,420,530
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Igf1
insulin like growth factor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:9452187
NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
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Il10
interleukin 10
treatment
ISO
CTD Direct Evidence: marker/mechanism|therapeutic associated with Sciatic Neuropathy
CTD RGD
PMID:7582491 PMID:17174526 PMID:22820166 PMID:23957449 PMID:24077211
RGD:7364792 RGD:7364827 RGD:7364865
NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
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Il13
interleukin 13
treatment
ISO
RGD
PMID:11399514
RGD:8549555
NCBI chrNW_004955408:4,046,406...4,049,795
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Il17a
interleukin 17A
treatment
ISO
RGD
PMID:23192794 PMID:23246025
RGD:9068942 RGD:9222699
NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962
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Il18
interleukin 18
treatment
ISO
associated with Peripheral Nerve Injuries
RGD
PMID:19036970
RGD:8655929
NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634
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Il1a
interleukin 1 alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12727271
NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
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Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism associated with Peripheral Nerve Injuries
RGD CTD
PMID:7582491 PMID:8741165 PMID:10401557 PMID:12727271 PMID:15317861 PMID:17320857 PMID:20937348 PMID:22265659 PMID:23159984 PMID:27093858 More...
RGD:1626676 RGD:6482671 RGD:7175548 RGD:7401209
NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
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Il1r1
interleukin 1 receptor type 1
ISO
RGD
PMID:11585580 PMID:19022353
RGD:8662898 RGD:8662903
NCBI chrNW_004955470:7,685,498...7,703,374
G
Il1rn
interleukin 1 receptor antagonist
treatment severity
ISO
associated with Arthritis, Experimental; rat model treated with human protein CTD Direct Evidence: marker/mechanism|therapeutic
RGD CTD
PMID:8864563 PMID:10903985 PMID:15317861 PMID:17174526 PMID:17959986 PMID:20937348 PMID:22933159 PMID:23092240 More...
RGD:6909165 RGD:6909175 RGD:7401210 RGD:8549800
NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
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Il2
interleukin 2
treatment
ISO
associated with Sciatic Neuropathy; mRNA,protein:increased expression:spinal cord:
RGD
PMID:12755376 PMID:18423867 PMID:22189457
RGD:8662973 RGD:8662977 RGD:8662980
NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
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Il33
interleukin 33
ISO
RGD
PMID:29329586
RGD:40400909
NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
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Il6
interleukin 6
ISO
associated with Foot Injuries; protein:increased expression:serum: mRNA:increased expression:dorsal root ganglion CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:7582491 PMID:10401557 PMID:18652822 PMID:18988309 PMID:23953943
RGD:10402830 RGD:8662979
NCBI chrNW_004955410:25,079,835...25,084,390
G
Il6r
interleukin 6 receptor
ISO
mRNA:increased expression:dorsal root ganglion
RGD
PMID:23953943
RGD:10402830
NCBI chrNW_004955545:932,814...979,359
Ensembl chrNW_004955545:950,765...981,762
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Insr
insulin receptor
treatment
ISO
CTD Direct Evidence: marker/mechanism associated with Diabetic Neuropathies
CTD RGD
PMID:18331706 PMID:23511693
RGD:10403050
NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149
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Itga1
integrin subunit alpha 1
ISO
PGE2-induced knock-down using a specific monoclonal antibody or RNAi
RGD
PMID:14984413 PMID:15836982
RGD:2302139 RGD:2302389
NCBI chrNW_004955446:14,439,571...14,582,236
Ensembl chrNW_004955446:14,446,300...14,577,605
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Itga2
integrin subunit alpha 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18234883
NCBI chrNW_004955446:14,309,516...14,421,991
Ensembl chrNW_004955446:14,309,349...14,422,170
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Itga3
integrin subunit alpha 3
ISO
knock-down using a specific monoclonal antibody or RNAi
RGD
PMID:14984413 PMID:15836982
RGD:2302139 RGD:2302389
NCBI chrNW_004955451:11,563,120...11,590,119
Ensembl chrNW_004955451:11,561,704...11,589,727
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Itga5
integrin subunit alpha 5
ISO
epinephrine-induced knock-down using a specific monoclonal antibody or RNAi
RGD
PMID:14984413 PMID:15836982
RGD:2302139 RGD:2302389
NCBI chrNW_004955458:1,635,554...1,657,609
Ensembl chrNW_004955458:1,632,282...1,658,295
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Itgb1
integrin subunit beta 1
ISO
knock-down using a specific monoclonal antibody or RNAi
RGD
PMID:14984413 PMID:15836982
RGD:2302139 RGD:2302389
NCBI chrNW_004955462:4,454,809...4,483,227
Ensembl chrNW_004955462:4,454,809...4,484,842
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Jak2
Janus kinase 2
treatment
ISO
associated with Diabetic Neuropathies
RGD
PMID:18636982 PMID:23511693
RGD:10403050 RGD:6483031
NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
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Jak3
Janus kinase 3
treatment
ISO
RGD
PMID:21434883
RGD:11533942
NCBI chrNW_004955524:3,399,895...3,412,018
Ensembl chrNW_004955524:3,401,642...3,411,643
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Kcnc4
potassium voltage-gated channel subfamily C member 4
ISO
RGD
PMID:17855600
RGD:10411908
NCBI chrNW_004955435:13,728,272...13,750,420
Ensembl chrNW_004955435:13,728,708...13,750,660
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Kcnk2
potassium two pore domain channel subfamily K member 2
ISO
RGD
PMID:16675954
RGD:9831112
NCBI chrNW_004955406:2,793,493...2,975,322
Ensembl chrNW_004955406:2,791,803...2,975,322
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Kcnq3
potassium voltage-gated channel subfamily Q member 3
ISO
associated with Bone Neoplasms;protein:decreased expression:dorsal root ganglia (rat)
RGD
PMID:23352759
RGD:9686417
NCBI chrNW_004955461:6,793,877...7,119,859
Ensembl chrNW_004955461:6,797,018...7,119,569
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Kmo
kynurenine 3-monooxygenase
treatment
ISO
RGD
PMID:26524415
RGD:13703043
NCBI chrNW_004955406:10,496,102...10,527,181
Ensembl chrNW_004955406:10,493,379...10,527,201
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Kng1
kininogen 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:2010815 PMID:2128375 PMID:3061568 PMID:7493622 PMID:7582491 PMID:7881729 PMID:9714424 PMID:9720808 PMID:10401557 PMID:10499367 PMID:10543429 PMID:15626726 PMID:16259764 PMID:16793879 PMID:18234883 PMID:21521205 More...
NCBI chrNW_004955420:20,989,197...21,016,084
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Lepr
leptin receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29143802
NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407
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Map1lc3a
microtubule associated protein 1 light chain 3 alpha
ISO
RGD
PMID:23665054
RGD:11560531
NCBI chrNW_004955422:26,774,466...26,776,024
Ensembl chrNW_004955422:26,774,922...26,775,884
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Map2k3
mitogen-activated protein kinase kinase 3
onset
ISO
RGD
PMID:19427893
RGD:7495807
NCBI chrNW_004955577:1,225,033...1,249,510
Ensembl chrNW_004955577:1,237,287...1,248,541
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Mapk1
mitogen-activated protein kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12941468 PMID:27093858
NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020
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Mapk3
mitogen-activated protein kinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12941468 PMID:27093858
NCBI chrNW_004955493:6,870,699...6,876,836
Ensembl chrNW_004955493:6,869,668...6,879,152
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Mapk7
mitogen-activated protein kinase 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17237256
NCBI chrNW_004955467:381,801...387,078
Ensembl chrNW_004955467:378,156...386,532
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Mapk8
mitogen-activated protein kinase 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27093858
NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784
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Mapk9
mitogen-activated protein kinase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27093858
NCBI chrNW_004955408:391,094...430,638
Ensembl chrNW_004955408:391,094...430,981
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Mc4r
melanocortin 4 receptor
ISO
protein:increased expression:dorsal root ganglia (rat)
RGD
PMID:20081244
RGD:6484233
NCBI chrNW_004955402:44,453,973...44,456,689
Ensembl chrNW_004955402:44,455,294...44,456,292
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Mecp2
methyl-CpG binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33010341
NCBI chrNW_004955580:674,014...737,586
Ensembl chrNW_004955580:679,109...735,288
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Men1
menin 1
ISO
associated with Sciatic Neuropathy;protein:increased expression:spinal cord dorsal horn (rat)
RGD
PMID:20369282
RGD:9589142
NCBI chrNW_004955422:20,356,491...20,363,374
Ensembl chrNW_004955422:20,356,491...20,363,575
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Mfn2
mitofusin 2
ISO
mRNA:decreased expression:spinal cord (rat) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:28587902
RGD:12910704
NCBI chrNW_004955486:1,937,873...1,962,577
Ensembl chrNW_004955486:1,937,802...1,962,772
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Mpz
myelin protein zero
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16676325
NCBI chrNW_004955468:13,041,911...13,047,026
Ensembl chrNW_004955468:13,041,011...13,047,284
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Mtor
mechanistic target of rapamycin kinase
ISO
RGD
PMID:24382350
RGD:10040983
NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
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Nectin1
nectin cell adhesion molecule 1
ISO
RGD
PMID:27394444
RGD:405866373
NCBI chrNW_004955412:20,683,007...20,745,069
Ensembl chrNW_004955412:20,682,861...20,745,069
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Nefh
neurofilament heavy chain
treatment
ISO
RGD
PMID:21071147
RGD:27226885
NCBI chrNW_004955455:3,735,330...3,744,714
Ensembl chrNW_004955455:3,735,410...3,744,107
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Ngf
nerve growth factor
treatment
ISO
CTD Direct Evidence: marker/mechanism associated with Osteoarthritis, Experimental associated with Peripheral Nerve Injuries; associated with Cystitis
CTD RGD
PMID:11425916 PMID:16203088 PMID:18448607 PMID:20457222 PMID:22839415 PMID:24095693 PMID:27208420 More...
RGD:402463955 RGD:405100717 RGD:7242799 RGD:7242803 RGD:7242849 RGD:8657088
NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059
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Ngfr
nerve growth factor receptor
treatment
ISO
associated with Brachial Plexus Neuropathies
RGD
PMID:23324933
RGD:10413898
NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305
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Nlgn2
neuroligin 2
ISO
RGD
PMID:23891900
RGD:9831150
NCBI chrNW_004955467:9,504,974...9,520,059
Ensembl chrNW_004955467:9,504,974...9,520,059
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Nos1
nitric oxide synthase 1
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:19300402 PMID:23909597
RGD:7257597
NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566
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Nos2
nitric oxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17989504 PMID:19300402
NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
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Npy
neuropeptide Y
treatment
ISO
associated with Sciatic Neuropathy
RGD
PMID:19556004
RGD:10448929
NCBI chrNW_004955410:26,348,388...26,355,232
Ensembl chrNW_004955410:26,348,504...26,355,297
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Nrg1
neuregulin 1
ISO
associated with Sciatic Neuropathy associated with interstitial cystitis;
RGD
PMID:22212401 PMID:30989724
RGD:10449019 RGD:405295490
NCBI chrNW_004955463:8,009,436...9,037,116
Ensembl chrNW_004955463:8,009,530...9,037,116
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Ntf3
neurotrophin 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15659614
NCBI chrNW_004955413:3,207,669...3,273,371
Ensembl chrNW_004955413:3,207,123...3,273,491
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Ntrk1
neurotrophic receptor tyrosine kinase 1
ISO
RGD
PMID:17667845 PMID:20351485
RGD:5144120 RGD:5684352
NCBI chrNW_004955545:2,929,704...2,947,579
Ensembl chrNW_004955545:2,929,704...2,947,579
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Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
associated with inflammation;protein:increased expression:dorsal root ganglion:
RGD
PMID:12470870 PMID:21958434
RGD:8657091 RGD:8657122
NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
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Ntsr1
neurotensin receptor 1
ISO
RGD
PMID:22396077
RGD:9743902
NCBI chrNW_004955528:1,348,616...1,394,798
Ensembl chrNW_004955528:1,348,555...1,394,868
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Oprk1
opioid receptor kappa 1
treatment
ISO
associated with Diabetes Mellitus, Experimental;
RGD
PMID:16924480
RGD:9834947
NCBI chrNW_004955454:12,741,577...12,751,282
Ensembl chrNW_004955454:12,744,765...12,752,226
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Oprl1
opioid related nociceptin receptor 1
ISO
associated with Sciatic Neuropathy;mRNA:increased expression:spinal cord lumbar segment,dorsal root ganglion:
RGD
PMID:12106803
RGD:9835017
NCBI chrNW_004955528:161,673...184,515
Ensembl chrNW_004955528:161,673...167,937
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Oprm1
opioid receptor mu 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17996026
NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817
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P2rx2
purinergic receptor P2X 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19383439
NCBI chrNW_004955482:418,101...422,058
Ensembl chrNW_004955482:419,213...421,583
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P2rx3
purinergic receptor P2X 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19383439
NCBI chrNW_004955511:2,389,717...2,410,968
Ensembl chrNW_004955511:2,389,717...2,411,008
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P2rx4
purinergic receptor P2X 4
treatment
ISO
associated with Peripheral Nerve Injuries;
RGD
PMID:29927790
RGD:40924654
NCBI chrNW_004955482:7,031,874...7,039,026
Ensembl chrNW_004955482:7,031,874...7,039,220
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P2ry12
purinergic receptor P2Y12
ISO
RGD
PMID:20136836 PMID:20398327
RGD:6480525 RGD:6480526
NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567
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Pawr
pro-apoptotic WT1 regulator
treatment
ISO
RGD
PMID:17179954
RGD:9835416
NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710
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Pdyn
prodynorphin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17670969
NCBI chrNW_004955415:13,106,087...13,119,497
Ensembl chrNW_004955415:13,106,062...13,119,515
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Penk
proenkephalin
treatment
ISO
associated with Diabetes Mellitus, Experimental;
RGD
PMID:23235561
RGD:10003116
NCBI chrNW_004955454:15,425,712...15,426,685
Ensembl chrNW_004955454:15,426,017...15,426,685
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Pla2g4a
phospholipase A2 group IVA
ISO
RGD
PMID:16203828
RGD:1642461
NCBI chrNW_004955406:25,257,361...25,392,079
Ensembl chrNW_004955406:25,257,355...25,394,206
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Pnoc
prepronociceptin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12665541 PMID:19231294
NCBI chrNW_004955403:50,735,567...50,755,892
Ensembl chrNW_004955403:50,735,390...50,755,902
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Pomc
proopiomelanocortin
treatment
ISO
associated with Inflammation
RGD
PMID:19934807
RGD:407580522
NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
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Ppp2ca
protein phosphatase 2 catalytic subunit alpha
ISO
RGD
PMID:26732138
RGD:11572421
NCBI chrNW_004955408:5,435,117...5,460,361
Ensembl chrNW_004955408:5,433,268...5,460,361
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Prkcb
protein kinase C beta
ISO
associated with inflammation;protein:increased activity:spinal cord
RGD
PMID:16360284
RGD:1625519
NCBI chrNW_004955493:2,395,494...2,710,522
Ensembl chrNW_004955493:2,395,109...2,710,934
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Prkce
protein kinase C epsilon
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11738263 PMID:12582831 PMID:20457222
NCBI chrNW_004955441:12,642,703...13,142,396
Ensembl chrNW_004955441:12,642,697...13,139,372
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Prkcg
protein kinase C gamma
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:12560106 PMID:19955894 PMID:27093858
RGD:28867224
NCBI chrNW_004955604:262,182...279,259
Ensembl chrNW_004955604:262,071...279,259
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Prkcz
protein kinase C zeta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27899695
NCBI chrNW_004955486:8,947,579...9,021,702
Ensembl chrNW_004955486:8,947,579...9,021,702
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Prkg1
protein kinase cGMP-dependent 1
treatment
ISO
RGD
PMID:14973199
RGD:7775058
NCBI chrNW_004955425:6,176,335...7,335,867
Ensembl chrNW_004955425:6,176,432...7,331,446
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Prok2
prokineticin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16793879
NCBI chrNW_004955421:16,325,519...16,339,458
Ensembl chrNW_004955421:16,325,519...16,337,980
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Prokr1
prokineticin receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16793879
NCBI chrNW_004955424:16,287,666...16,301,713
Ensembl chrNW_004955424:16,287,653...16,301,713
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Ptafr
platelet activating factor receptor
treatment
ISO
RGD
PMID:16925995
RGD:10041052
NCBI chrNW_004955452:7,309,854...7,345,579
Ensembl chrNW_004955452:7,311,901...7,312,929
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Ptger1
prostaglandin E receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11375261
NCBI chrNW_004955415:33,063,052...33,067,580
Ensembl chrNW_004955415:33,063,052...33,067,580
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Ptger3
prostaglandin E receptor 3
ISO
protein:increased expression:lumbar spinal cord dorsal horn (rat)
RGD
PMID:17413918
RGD:5688169
NCBI chrNW_004955423:21,096,926...21,164,435
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Ptger4
prostaglandin E receptor 4
treatment
ISO
RGD
PMID:20423341
RGD:10003041
NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822
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Ptges3
prostaglandin E synthase 3
ISO
RGD
PMID:16192391
RGD:5688057
NCBI chrNW_004955458:4,203,075...4,209,967
Ensembl chrNW_004955458:4,203,076...4,209,910
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Ptgs1
prostaglandin-endoperoxide synthase 1
ISO
protein:increased expression:spinal cord CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17413918 PMID:17989504
RGD:5688169
NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305
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Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15464832 PMID:17112505 PMID:17989504
RGD:5688224
NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
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Pthlh
parathyroid hormone like hormone
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16769263
NCBI chrNW_004955505:6,834,533...6,846,909
Ensembl chrNW_004955505:6,834,533...6,847,335
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Raf1
Raf-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18976650
NCBI chrNW_004955429:17,980,956...18,049,723
Ensembl chrNW_004955429:18,025,932...18,049,723
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Rgs4
regulator of G protein signaling 4
treatment
ISO
associated with lesion of sciatic nerve
RGD
PMID:27641322
RGD:13524513
NCBI chrNW_004955462:13,340,812...13,347,598
Ensembl chrNW_004955462:13,338,960...13,347,610
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Scn10a
sodium voltage-gated channel alpha subunit 10
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16545521 PMID:19070548
RGD:6484253
NCBI chrNW_004955427:25,157,179...25,244,020
Ensembl chrNW_004955427:25,157,179...25,243,473
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Scn11a
sodium voltage-gated channel alpha subunit 11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23264124
NCBI chrNW_004955427:24,917,709...25,109,499
Ensembl chrNW_004955427:24,989,615...25,109,550
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Sin3a
SIN3 transcription regulator family member A
ISO
associated with Arthritis, Experimental;mRNA:decreased expression:spinal cord, neuron
RGD
PMID:17553988
RGD:9495916
NCBI chrNW_004955450:2,804,551...2,870,450
Ensembl chrNW_004955450:2,808,130...2,870,450
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Slc12a5
solute carrier family 12 member 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20086212
NCBI chrNW_004955445:11,252,732...11,290,890
Ensembl chrNW_004955445:11,252,732...11,291,501
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Slc17a8
solute carrier family 17 member 8
ISO
protein:increased expression:dorsal horn of spinal cord, neuron
RGD
PMID:22160634
RGD:9999169
NCBI chrNW_004955405:36,063,688...36,115,312
Ensembl chrNW_004955405:36,063,688...36,115,312
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Sparc
secreted protein acidic and cysteine rich
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20714283
NCBI chrNW_004955408:6,100,123...6,122,460
Ensembl chrNW_004955408:6,099,003...6,122,459
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
ISO
protein:increased phosphorylation:spinal cord
RGD
PMID:27394444
RGD:405866373
NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
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Stat3
signal transducer and activator of transcription 3
treatment
ISO
RGD
PMID:24098399
RGD:8694290
NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
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Syn2
synapsin II
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18701217
NCBI chrNW_004955429:14,676,286...14,724,625
G
Tac1
tachykinin precursor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8864563 PMID:9714424 PMID:10499367 PMID:12351280 PMID:12787826 PMID:15626726 PMID:16259764 PMID:18234883 PMID:19231294 More...
NCBI chrNW_004955432:13,991,647...13,999,665
Ensembl chrNW_004955432:13,991,414...13,999,728
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Tacr1
tachykinin receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15964684 PMID:17123731
NCBI chrNW_004955424:10,614,340...10,761,872
Ensembl chrNW_004955424:10,614,340...10,761,872
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Tcf7l2
transcription factor 7 like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33607128
NCBI chrNW_004955431:18,020,309...18,207,926
Ensembl chrNW_004955431:18,020,409...18,209,134
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Tgfbr1
transforming growth factor beta receptor 1
ISO
associated with Experimental Pancreatitis, Chronic
RGD
PMID:26645248
RGD:14995470
NCBI chrNW_004955419:26,490,899...26,546,349
Ensembl chrNW_004955419:26,490,899...26,547,017
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Thbd
thrombomodulin
treatment
ISO
CTD Direct Evidence: therapeutic associated with Inflammation
CTD RGD
PMID:24004409 PMID:27474498
RGD:11038687
NCBI chrNW_004955415:30,222,830...30,226,406
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Tlr2
toll like receptor 2
ISO
RGD
PMID:17355971 PMID:24204973
RGD:8553059 RGD:8553185
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
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Tlr4
toll like receptor 4
ISO
RGD
PMID:15809417 PMID:20714435 PMID:24204973
RGD:4144070 RGD:7815040 RGD:8553185
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Tnf
tumor necrosis factor
ISO
protein:increased expression:lumbar vertebra: mRNA,protein:increased expression:spinal cord: associated with Diabetic Neuropathies; CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:7582491 PMID:7881729 PMID:10401557 PMID:10825476 PMID:12727271 PMID:16472913 PMID:16675114 PMID:17304130 PMID:17320857 PMID:17459378 PMID:18463260 PMID:18582539 PMID:18790011 PMID:20383154 PMID:21104419 PMID:26141506 PMID:27093858 More...
RGD:7387300 RGD:7387302 RGD:7394737 RGD:7394741 RGD:7394757 RGD:7401179
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
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Tnfrsf11b
TNF receptor superfamily member 11b
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16769263
NCBI chrNW_004955417:24,804,708...24,831,338
Ensembl chrNW_004955417:24,804,664...24,831,894
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Tnfrsf1a
TNF receptor superfamily member 1A
treatment
ISO
associated with Sciatic Neuropathy
RGD
PMID:12752784 PMID:20417692 PMID:21145890 PMID:21712071 PMID:22652595 PMID:24257399 More...
RGD:5130913 RGD:5130939 RGD:8548873 RGD:8661726 RGD:8661737 RGD:8661750
NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
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Tnfrsf1b
TNF receptor superfamily member 1B
ISO
associated with Sciatic Neuropathy
RGD
PMID:18463260 PMID:22652595
RGD:5130960 RGD:8661750
NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362
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Tph2
tryptophan hydroxylase 2
ISO
RGD
PMID:27983993
RGD:597830167
NCBI chrNW_004955405:11,877,474...11,981,035
Ensembl chrNW_004955405:11,886,206...11,982,550
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Trpa1
transient receptor potential cation channel subfamily A member 1
ISO
associated with Peripheral Nerve Injuries; CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:18234885 PMID:18954467 PMID:21481532 PMID:23523557
RGD:10043618
NCBI chrNW_004955444:7,876,284...7,922,010
Ensembl chrNW_004955444:7,876,429...7,921,372
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Trpc1
transient receptor potential cation channel subfamily C member 1
ISO
associated with Inflammation
RGD
PMID:19439599
RGD:7247605
NCBI chrNW_004955508:3,143,868...3,211,613
Ensembl chrNW_004955508:3,143,868...3,211,613
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Trpc6
transient receptor potential cation channel subfamily C member 6
ISO
RGD
PMID:19439599
RGD:7247605
NCBI chrNW_004955412:4,905,039...5,019,678
Ensembl chrNW_004955412:4,906,650...4,950,525
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Trpv1
transient receptor potential cation channel subfamily V member 1
ISO
CTD Direct Evidence: marker/mechanism associated with inflammation;protein:increased expression:dorsal root ganglion:
CTD RGD
PMID:12151517 PMID:18234885 PMID:18774343 PMID:21958434 PMID:23006841
RGD:8657122
NCBI chrNW_004955467:13,221,391...13,239,089
Ensembl chrNW_004955467:13,221,391...13,239,089
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Trpv4
transient receptor potential cation channel subfamily V member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18234883
NCBI chrNW_004955455:8,744,865...8,781,644
Ensembl chrNW_004955455:8,744,176...8,783,741
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Vip
vasoactive intestinal peptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12787826
NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792
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Aqp4
aquaporin 4
ISO
RGD
PMID:20851747
RGD:8696005
NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709
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Hdac4
histone deacetylase 4
ISO
RGD
PMID:19672313
RGD:9681457
NCBI chrNW_004955542:1,629,691...1,886,160
Ensembl chrNW_004955542:1,629,691...1,886,210
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Cebpe
CCAAT enhancer binding protein epsilon
ISO
ClinVar Annotator: match by term: Pelger-Huet-like anomaly and episodic fever with abdominal pain
OMIM ClinVar
PMID:4831644 PMID:31201888
NCBI chrNW_004955409:37,186,282...37,187,914
Ensembl chrNW_004955409:37,186,039...37,187,921
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Ppm1d
protein phosphatase, Mg2+/Mn2+ dependent 1D
ISO
ClinVar Annotator: match by term: Intellectual developmental disorder with gastrointestinal difficulties and high pain threshold | ClinVar Annotator: match by term: PPM1D-related condition
OMIM ClinVar
PMID:23907125 PMID:24262437 PMID:25741868 PMID:28343630 PMID:28492532 PMID:28852847 PMID:29752822 PMID:29758292 PMID:29758562 PMID:30216591 PMID:30388424 PMID:30795918 PMID:31916397 PMID:33057194 PMID:35982159 PMID:37183572 PMID:37378944 More...
NCBI chrNW_004955451:1,878,110...1,915,794
Ensembl chrNW_004955451:1,878,629...1,915,654
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Agt
angiotensinogen
ISO
mRNA:increased expression:myocardium
RGD
PMID:11451295
RGD:8548894
NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
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Agtr1
angiotensin II receptor type 1
ISO
mRNA:increased expression:myocardium
RGD
PMID:11451295
RGD:8548894
NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255
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Akt1
AKT serine/threonine kinase 1
ISO
protein:increased serine phosphorylation:platelet
RGD
PMID:20467748
RGD:5509094
NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
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Apoa4
apolipoprotein A4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20367977
RGD:5685646
NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
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Bdnf
brain derived neurotrophic factor
ISO
RGD
PMID:16186425
RGD:4891111
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
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Cxcl8
C-X-C motif chemokine ligand 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:10660968
NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
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Edn1
endothelin 1
ISO
associated with Coronary Artery Disease;protein:increased expression:coronary sinus, plasma (human)
RGD
PMID:14556009
RGD:8661755
NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
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F7
coagulation factor VII
ISO
protein:increased expression:plasma (human)
RGD
PMID:10653827
RGD:2312399
NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
ISO
RGD
PMID:18333374
RGD:5508458
NCBI chrNW_004955425:25,362,165...25,380,611
Ensembl chrNW_004955425:25,359,884...25,380,745
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Itga2
integrin subunit alpha 2
susceptibility
ISO
RGD
PMID:15104219
RGD:1582303
NCBI chrNW_004955446:14,309,516...14,421,991
Ensembl chrNW_004955446:14,309,349...14,422,170
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Itgam
integrin subunit alpha M
ameliorates
ISO
protein:decreased expression:neutrophil (human)
RGD
PMID:18043994
RGD:329901840
NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759
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Itih4
inter-alpha-trypsin inhibitor heavy chain 4
ISO
RGD
PMID:10486281
RGD:1582334
NCBI chrNW_004955430:2,772,064...2,787,912
Ensembl chrNW_004955430:2,770,373...2,789,131
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Pappa
pappalysin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11586954
NCBI chrNW_004955419:11,415,666...11,645,994
Ensembl chrNW_004955419:11,420,638...11,646,145
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Plau
plasminogen activator, urokinase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:2382605
NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209
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Pten
phosphatase and tensin homolog
ISO
RNA:increased expression:serum
RGD
PMID:32595526
RGD:401851053
NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829
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Selp
selectin P
ISO
protein:increased expression:serum
RGD
PMID:21162967
RGD:6219003
NCBI chrNW_004955462:7,658,371...7,692,870
Ensembl chrNW_004955462:7,652,437...7,693,994
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Serpinc1
serpin family C member 1
treatment
ISO
RGD
PMID:8122184
RGD:11035255
NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948
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Sod3
superoxide dismutase 3
ISO
RGD
PMID:14592844
RGD:1580841
NCBI chrNW_004955480:257,716...263,149
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Cxcl8
C-X-C motif chemokine ligand 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11280320
NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
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Plat
plasminogen activator, tissue type
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:7888893
NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
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Sparc
secreted protein acidic and cysteine rich
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20714283
NCBI chrNW_004955408:6,100,123...6,122,460
Ensembl chrNW_004955408:6,099,003...6,122,459
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Bdkrb1
bradykinin receptor B1
ISO
mRNA:increased expression:blood, mononuclear cell
RGD
PMID:17852785
RGD:4890450
NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691
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Bdkrb2
bradykinin receptor B2
ISO
mRNA:increased expression:blood, mononuclear cell
RGD
PMID:17852785
RGD:4890450
NCBI chrNW_004955438:16,514,300...16,537,160
Ensembl chrNW_004955438:16,511,759...16,537,172
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Mthfr
methylenetetrahydrofolate reductase
ISO
DNA:transition:cds:g.677C>T (human) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17491230
RGD:4891159
NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
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Tnfrsf11b
TNF receptor superfamily member 11b
ISO
protein:decreased expression:serum
RGD
PMID:15648548
RGD:1620974
NCBI chrNW_004955417:24,804,708...24,831,338
Ensembl chrNW_004955417:24,804,664...24,831,894
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Comt
catechol-O-methyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25218601
NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
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Esr1
estrogen receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25218601
NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353
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Gch1
GTP cyclohydrolase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25218601
NCBI chrNW_004955409:8,624,225...8,670,436
Ensembl chrNW_004955409:8,624,468...8,668,614
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Lama2
laminin subunit alpha 2
ISO
ClinVar Annotator: match by term: Myalgia
ClinVar
PMID:9674786 PMID:18700894 PMID:25741868 PMID:28445022 PMID:28492532 PMID:30055037 PMID:32904964 More...
NCBI chrNW_004955436:9,829,777...10,400,101
Ensembl chrNW_004955436:9,830,030...10,399,891
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Ryr1
ryanodine receptor 1
ISO
ClinVar Annotator: match by term: Myalgia
ClinVar
PMID:24195946 PMID:25741868 PMID:28259615 PMID:28492532 PMID:33564012 PMID:34008892 More...
NCBI chrNW_004955468:879,807...1,000,118
Ensembl chrNW_004955468:879,951...1,000,036
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Slc12a3
solute carrier family 12 member 3
ISO
ClinVar Annotator: match by term: Myalgia
ClinVar
PMID:8528245 PMID:9734597 PMID:10988270 PMID:12039972 PMID:17329572 PMID:18391953 PMID:21415153 PMID:22009145 PMID:23328711 PMID:25741868 PMID:26467025 PMID:26921350 PMID:28492532 PMID:35591852 PMID:35628451 More...
NCBI chrNW_004955433:14,553,752...14,588,317
Ensembl chrNW_004955433:14,553,758...14,587,602
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Slc2a1
solute carrier family 2 member 1
ISO
ClinVar Annotator: match by term: Myalgia
ClinVar
PMID:25741868 PMID:28492532
NCBI chrNW_004955537:2,408,042...2,438,788
Ensembl chrNW_004955537:2,408,042...2,439,511
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Dtna
dystrobrevin alpha
ISO
ClinVar Annotator: match by term: Myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis
ClinVar
PMID:25741868 PMID:36799992
NCBI chrNW_004955402:21,414,122...21,676,389
Ensembl chrNW_004955402:21,315,889...21,673,044
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Mlip
muscular LMNA interacting protein
ISO
ClinVar Annotator: match by term: Myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis
OMIM ClinVar
PMID:25741868 PMID:34581780 PMID:34935254 PMID:35672413 PMID:35915960
NCBI chrNW_004955411:1,852,895...2,100,617
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Dtna
dystrobrevin alpha
ISO
ClinVar Annotator: match by term: MYOPATHY WITH MYALGIA, INCREASED SERUM CREATINE KINASE, AND WITH OR WITHOUT EPISODIC RHABDOMYOLYSIS 2
OMIM ClinVar
PMID:36799992
NCBI chrNW_004955402:21,414,122...21,676,389
Ensembl chrNW_004955402:21,315,889...21,673,044
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Comt
catechol-O-methyltransferase
severity
ISO
associated with breast cancer;DNA:missense mutation:cds:p.V158M (human)
RGD
PMID:21898113
RGD:8662332
NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
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Adra2a
adrenoceptor alpha 2A
ISO
RGD
PMID:12946573
RGD:6893571
NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240
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Ager
advanced glycosylation end-product specific receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25014009
NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
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Aqp9
aquaporin 9
ameliorates
ISO
RGD
PMID:31746418
RGD:152995474
NCBI chrNW_004955450:16,253,706...16,346,602
Ensembl chrNW_004955450:16,253,571...16,302,657
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Cacna2d1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17442347 PMID:18400411 PMID:19339603 PMID:24133248
NCBI chrNW_004955410:3,544,398...3,963,582
Ensembl chrNW_004955410:3,619,740...3,964,239
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Cdk5
cyclin dependent kinase 5
ameliorates
ISO
RGD
PMID:24659417
RGD:401940123
NCBI chrNW_004955491:5,491,744...5,497,280
Ensembl chrNW_004955491:5,491,744...5,497,280
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Cfl1
cofilin 1
treatment
ISO
associated with Sciatic Neuropathy
RGD
PMID:27216618
RGD:11568694
NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
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Ctss
cathepsin S
ISO
RGD
PMID:17551020 PMID:18700000
RGD:5686878 RGD:5686911
NCBI chrNW_004955413:99,279...124,793
Ensembl chrNW_004955413:99,159...124,042
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Ctsz
cathepsin Z
ISO
RGD
PMID:18700000
RGD:5686878
NCBI chrNW_004955445:586,901...597,753
Ensembl chrNW_004955445:586,902...597,753
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Cxcr4
C-X-C motif chemokine receptor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17292584
NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109
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Drd1
dopamine receptor D1
ISO
RGD
PMID:22171983
RGD:6907447
NCBI chrNW_004955408:28,003,229...28,006,595
Ensembl chrNW_004955408:28,003,229...28,006,595
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Drd2
dopamine receptor D2
ISO
RGD
PMID:22171983 PMID:22902996
RGD:6907443 RGD:6907447
NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
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Foxp3
forkhead box P3
treatment
ISO
mRNA:increased expression: L4-L5 of the spinal cord
RGD
PMID:30858084
RGD:38599004
NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606
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Gal
galanin and GMAP prepropeptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18400411
NCBI chrNW_004955422:17,202,770...17,207,948
Ensembl chrNW_004955422:17,202,946...17,207,948
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Gch1
GTP cyclohydrolase 1
treatment
ISO
RGD
PMID:19922668
RGD:401700384
NCBI chrNW_004955409:8,624,225...8,670,436
Ensembl chrNW_004955409:8,624,468...8,668,614
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Gfra1
GDNF family receptor alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18400411
NCBI chrNW_004955431:20,859,152...21,070,886
Ensembl chrNW_004955431:20,866,685...21,070,853
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Gja1
gap junction protein alpha 1
ISO
associated with Spinal Cord Injuries;
RGD
PMID:22951907
RGD:7364890
NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
ISO
RGD
PMID:24659417
RGD:401940123
NCBI chrNW_004955442:8,171,114...8,565,187
Ensembl chrNW_004955442:8,174,232...8,562,059
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Grk1
G protein-coupled receptor kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:31432094
NCBI chrNW_004955404:343,009...353,683
Ensembl chrNW_004955404:343,009...353,683
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Grk2
G protein-coupled receptor kinase 2
treatment
ISO
RGD
PMID:24216329
RGD:13792703
NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412
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Grm5
glutamate metabotropic receptor 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19840219
NCBI chrNW_004955414:4,424,245...4,919,399
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Hmgb1
high mobility group box 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25014009
NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
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Htr1a
5-hydroxytryptamine receptor 1A
ISO
protein:increased expression:dorsal raphe nucleus
RGD
PMID:31045847
RGD:405849276
NCBI chrNW_004955446:4,913,181...4,917,726
Ensembl chrNW_004955446:4,913,884...4,915,146
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Htr2c
5-hydroxytryptamine receptor 2C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28011743
NCBI chrNW_004955490:912,615...1,126,347
Ensembl chrNW_004955490:910,415...1,126,373
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Il10
interleukin 10
treatment
ISO
RGD
PMID:16949747 PMID:24077211 PMID:25078297
RGD:11049468 RGD:1598632 RGD:7364865
NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
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Il12b
interleukin 12B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:31432094
NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620
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Itgam
integrin subunit alpha M
ISO
mRNA:increased expression:lumbar vertebra
RGD
PMID:15145554
RGD:1342461
NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759
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Kdr
kinase insert domain receptor
ISO
RGD
PMID:20705122
RGD:5684389
NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
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LOC102011010
steroid 17-alpha-hydroxylase/17,20 lyase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17720801
NCBI chrNW_004955485:7,615,132...7,652,899
Ensembl chrNW_004955485:7,645,363...7,650,658
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Nfatc1
nuclear factor of activated T cells 1
ISO
RGD
PMID:23386250
RGD:329337338
NCBI chrNW_004955402:62,558,392...62,674,347
Ensembl chrNW_004955402:62,558,286...62,674,457
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Nfatc4
nuclear factor of activated T cells 4
treatment
ISO
RGD
PMID:23386250
RGD:329337338
NCBI chrNW_004955409:35,931,208...35,941,555
Ensembl chrNW_004955409:35,931,173...35,940,696
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Nos1
nitric oxide synthase 1
treatment
ISO
RGD
PMID:23342771
RGD:7257658
NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566
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Ntrk1
neurotrophic receptor tyrosine kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18400411
NCBI chrNW_004955545:2,929,704...2,947,579
Ensembl chrNW_004955545:2,929,704...2,947,579
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Oprm1
opioid receptor mu 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14718584 PMID:18400411
NCBI chrNW_004955439:7,870,563...7,923,817
Ensembl chrNW_004955439:7,757,569...7,923,817
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P2ry12
purinergic receptor P2Y12
ISO
RGD
PMID:20665560
RGD:6480524
NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567
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Pomc
proopiomelanocortin
treatment
ISO
RGD
PMID:23624847
RGD:407574732
NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
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Prkg1
protein kinase cGMP-dependent 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30152261
NCBI chrNW_004955425:6,176,335...7,335,867
Ensembl chrNW_004955425:6,176,432...7,331,446
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Scn10a
sodium voltage-gated channel alpha subunit 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18400411
NCBI chrNW_004955427:25,157,179...25,244,020
Ensembl chrNW_004955427:25,157,179...25,243,473
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Scn9a
sodium voltage-gated channel alpha subunit 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19557861
NCBI chrNW_004955449:7,858,156...8,017,569
Ensembl chrNW_004955449:7,923,801...8,017,569
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Socs1
suppressor of cytokine signaling 1
treatment
ISO
RGD
PMID:27059231
RGD:151347419
NCBI chrNW_004955442:7,321,337...7,323,109
Ensembl chrNW_004955442:7,321,337...7,323,109
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
treatment
ISO
RGD
PMID:33746000
RGD:150521727
NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
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Tac1
tachykinin precursor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18400411
NCBI chrNW_004955432:13,991,647...13,999,665
Ensembl chrNW_004955432:13,991,414...13,999,728
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Tgfb1
transforming growth factor beta 1
treatment
ISO
RGD
PMID:24979268
RGD:11073677
NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
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Tlr4
toll like receptor 4
ISO
mRNA:increased expression:lumbar vertebra
RGD
PMID:15145554
RGD:1342461
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20846523
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
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Tnfsf8
TNF superfamily member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:31432094
NCBI chrNW_004955419:12,763,343...12,790,044
Ensembl chrNW_004955419:12,762,748...12,788,117
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
treatment
ISO
RGD
PMID:21107265
RGD:405650611
NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728
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Grm8
glutamate metabotropic receptor 8
ISO
RGD
PMID:17113112
RGD:6771186
NCBI chrNW_004955479:7,520,537...8,279,942
Ensembl chrNW_004955479:7,520,396...8,279,755
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Pdyn
prodynorphin
ISO
RGD
PMID:25663984
RGD:401851903
NCBI chrNW_004955415:13,106,087...13,119,497
Ensembl chrNW_004955415:13,106,062...13,119,515
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Pomc
proopiomelanocortin
ISO
RGD
PMID:21380811
RGD:5508807
NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
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Ptger4
prostaglandin E receptor 4
ISO
RGD
PMID:21371033
RGD:6483537
NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822
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Ptgis
prostaglandin I2 synthase
ameliorates
ISO
RGD
PMID:26611322
RGD:11536046
NCBI chrNW_004955445:8,624,228...8,663,385
Ensembl chrNW_004955445:8,623,430...8,677,658
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Vip
vasoactive intestinal peptide
ISO
RGD
PMID:19467283
RGD:5685608
NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792
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Ep300
E1A binding protein p300
treatment
ISO
mRNA:increased expression:lumbar spinal cord (rat)
RGD
PMID:23176208
RGD:7327202
NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933
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Hmgb1
high mobility group box 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27474498
NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
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Thbd
thrombomodulin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27474498
NCBI chrNW_004955415:30,222,830...30,226,406
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Tlr4
toll like receptor 4
treatment
ISO
RGD
PMID:18615568
RGD:7815041
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Tnf
tumor necrosis factor
ISO
protein:increased expression:Schwann cell
RGD
PMID:9514564 PMID:10825476 PMID:11376190 PMID:18394803
RGD:7394735 RGD:7394739 RGD:7394740 RGD:7394741
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
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Idh1
isocitrate dehydrogenase (NADP(+)) 1
ISO
ClinVar Annotator: match by term: Paroxysmal extreme pain disorder
ClinVar
PMID:25741868 PMID:34298581
NCBI chrNW_004955457:6,851,542...6,869,452
Ensembl chrNW_004955457:6,851,517...6,872,367
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Scn9a
sodium voltage-gated channel alpha subunit 9
ISO
ClinVar Annotator: match by term: Paroxysmal extreme pain disorder | ClinVar Annotator: match by term: RECTAL PAIN, FAMILIAL
OMIM ClinVar
PMID:15955112 PMID:17145499 PMID:18060017 PMID:18414213 PMID:18518989 PMID:18599537 PMID:19369487 PMID:19633428 PMID:19763161 PMID:20038812 PMID:20301342 PMID:20478850 PMID:20635406 PMID:21094958 PMID:21115638 PMID:21698661 PMID:21939494 PMID:22035805 PMID:22136189 PMID:22539570 PMID:22826602 PMID:23129781 PMID:23232607 PMID:23280954 PMID:23292638 PMID:23450472 PMID:23874707 PMID:23895530 PMID:24033266 PMID:24088041 PMID:24776970 PMID:24817410 PMID:24820863 PMID:24848745 PMID:25250524 PMID:25316021 PMID:25741868 PMID:25852444 PMID:25993546 PMID:25995458 PMID:26220970 PMID:26264438 PMID:26284228 PMID:26392352 PMID:26467025 PMID:26633545 PMID:26675522 PMID:26770814 PMID:26920677 PMID:27301361 PMID:27504264 PMID:27525141 PMID:27608006 PMID:27843123 PMID:27884173 PMID:27956748 PMID:27957625 PMID:28073787 PMID:28103821 PMID:28235406 PMID:28440294 PMID:28488083 PMID:28492532 PMID:29176367 PMID:29264398 PMID:29358611 PMID:29500686 PMID:29653220 PMID:29911575 PMID:29934995 PMID:29961513 PMID:30316835 PMID:30392441 PMID:30416015 PMID:30478917 PMID:30538988 PMID:30554136 PMID:30569495 PMID:30642272 PMID:30672368 PMID:30834459 PMID:31193310 PMID:31372899 PMID:31394368 PMID:31780880 PMID:31847883 PMID:32011655 PMID:32601768 PMID:32707200 PMID:32719824 PMID:32766464 PMID:33087732 PMID:33216760 PMID:33487118 PMID:34426522 PMID:36011376 PMID:36722722 PMID:37003485 PMID:37079850 PMID:37175987 PMID:37195288 PMID:37557164 PMID:37820178 PMID:38134749 PMID:38263462 PMID:38394191 More...
NCBI chrNW_004955449:7,858,156...8,017,569
Ensembl chrNW_004955449:7,923,801...8,017,569
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Cxcl8
C-X-C motif chemokine ligand 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11280320
NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
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Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
mRNA:increased expression:dorsal root ganglion
RGD
PMID:25880108
RGD:407987076
NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
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Scn8a
sodium voltage-gated channel alpha subunit 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23382806
NCBI chrNW_004955547:2,086,215...2,201,300
Ensembl chrNW_004955547:2,086,178...2,195,971
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Scn9a
sodium voltage-gated channel alpha subunit 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23382806
NCBI chrNW_004955449:7,858,156...8,017,569
Ensembl chrNW_004955449:7,923,801...8,017,569
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Abcb1
ATP binding cassette subfamily B member 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20627697
NCBI chrNW_004955432:4,911,774...5,085,349
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Crhr1
corticotropin releasing hormone receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28434951
NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825
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Dusp6
dual specificity phosphatase 6
ISO
associated with Inflammation
RGD
PMID:24155322
RGD:7771585
NCBI chrNW_004955405:26,662,018...26,666,314
Ensembl chrNW_004955405:26,662,018...26,666,314
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Icam1
intercellular adhesion molecule 1
ISO
protein:increased expression:plasma
RGD
PMID:9415270
RGD:8547713
NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
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Kcnj8
potassium inwardly rectifying channel subfamily J member 8
ISO
RGD
PMID:11984590
RGD:1581700
NCBI chrNW_004955413:17,364,447...17,371,255
Ensembl chrNW_004955413:17,364,213...17,371,255
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Bdnf
brain derived neurotrophic factor
ISO
RGD
PMID:23313710
RGD:8655857
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
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Bloc1s2
biogenesis of lysosomal organelles complex 1 subunit 2
ISO
RGD
PMID:16176350
RGD:2302154
NCBI chrNW_004955507:6,138,511...6,144,823
Ensembl chrNW_004955507:6,138,071...6,144,823
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Tnfrsf1b
TNF receptor superfamily member 1B
treatment
ISO
RGD
PMID:22425187
RGD:7245944
NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362
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F7
coagulation factor VII
ISO
protein:increased activity:plasma (human)
RGD
PMID:17357481
RGD:11049525
NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665
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Mmp9
matrix metallopeptidase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20981132
NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
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Rbp4
retinol binding protein 4
ISO
protein:increased expression:blood serum (human)
RGD
PMID:25142320
RGD:329845867
NCBI chrNW_004955507:112,342...120,050
Ensembl chrNW_004955507:108,669...120,584
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Tlr4
toll like receptor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20981132
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20981132
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
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Npy1r
neuropeptide Y receptor Y1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:18809749
NCBI chrNW_004955403:41,681,834...41,693,094
Ensembl chrNW_004955403:41,681,728...41,694,020
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Adra2a
adrenoceptor alpha 2A
ISO
RGD
PMID:20047711
RGD:6480482
NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240
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Bdnf
brain derived neurotrophic factor
ISO
associated with Colitis; protein:increased expression:dorsal root ganglion:
RGD
PMID:19932037 PMID:21997550
RGD:8655978 RGD:8657331
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
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Ephb2
EPH receptor B2
ameliorates
ISO
RGD
PMID:33880135
RGD:127285657
NCBI chrNW_004955452:2,844,713...2,986,790
Ensembl chrNW_004955452:2,844,713...2,980,445
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Gch1
GTP cyclohydrolase 1
treatment
ISO
DNA:haplotype
RGD
PMID:25783971
RGD:401700391
NCBI chrNW_004955409:8,624,225...8,670,436
Ensembl chrNW_004955409:8,624,468...8,668,614
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Penk
proenkephalin
treatment
ISO
RGD
PMID:23316929
RGD:10003040
NCBI chrNW_004955454:15,425,712...15,426,685
Ensembl chrNW_004955454:15,426,017...15,426,685
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Trpa1
transient receptor potential cation channel subfamily A member 1
ISO
associated with Colitis;
RGD
PMID:23099257
RGD:10043788
NCBI chrNW_004955444:7,876,284...7,922,010
Ensembl chrNW_004955444:7,876,429...7,921,372
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Trpc4
transient receptor potential cation channel subfamily C member 4
ISO
RGD
PMID:24388923
RGD:13825245
NCBI chrNW_004955431:8,283,585...8,479,524
Ensembl chrNW_004955431:8,282,812...8,479,944
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all