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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Coronary Disease
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Accession:DOID:9000528 term browser browse the term
Definition:An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Synonyms:exact_synonym: CHD;   Coronary Diseases;   MMP3-RELATED CONDITION;   coronary heart disease;   coronary heart diseases
 narrow_synonym: CORONARY ARTERY DISEASE, EARLY-ONSET;   THREE VESSEL CORONARY DISEASE;   chronic coronary heart disease
 related_synonym: CHDS1;   CHDS2;   CHDS3;   CHDS4;   CHDS5;   CHDS6;   CHDS7;   CHDS8;   CHDS9;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 1;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 2;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 3;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 4;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 5;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 6;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 7;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 8;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 9;   Coronary artery disease, susceptibility to;   Coronary heart disease in familial hypercholesterolemia, protection against
 primary_id: MESH:D003327
 alt_id: MIM:300464;   MIM:607339;   MIM:608316;   MIM:608318;   MIM:608901;   MIM:610938;   MIM:611139;   MIM:612030;   MIM:614466


show annotations for term's descendants           Sort by:
Coronary Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO ClinVar Annotator: match by term: Early-onset coronary artery disease ClinVar NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Early-onset coronary artery disease 		CTD
ClinVar		 PMID:19060911 PMID:28492532 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO ClinVar Annotator: match by term: Early-onset coronary artery disease ClinVar PMID:3706300 PMID:6110091 PMID:11099417 PMID:11264985 PMID:11452359 More... NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar PMID:25741868 NCBI chr 3:30,560,172...30,604,758 JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:8170965 PMID:9488209 RGD:8142364 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Ace2 angiotensin converting enzyme 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :8790G>A (human) RGD PMID:18753062 RGD:2313798 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Ada adenosine deaminase ISO protein:increased expression:leukocyte RGD PMID:17259686 RGD:1624286 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ISO protein:decreased activity:plasma (human)
ClinVar Annotator: match by term: Three Vessel Coronary Disease 		ClinVar
RGD		 PMID:25741868 PMID:28492532 PMID:12670342 RGD:10449044 NCBI chr 3:30,697,354...30,736,539
Ensembl chr 3:30,697,942...30,736,540 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar PMID:25741868 NCBI chr 8:99,584,529...99,624,132
Ensembl chr 8:99,584,529...99,624,132 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression ISO associated with Diabetes mellitus, Type2; RGD PMID:22207678 PMID:22019747 RGD:5686379, RGD:5686406 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO DNA:polymorphism: :p.Q27E RGD PMID:12682000 RGD:1601128 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Adrb3 adrenoceptor beta 3 susceptibility ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994(human) RGD
GAD		 PMID:10421225 PMID:20536507 PMID:15118671 RGD:1559326, RGD:5684776, RGD:1331525 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420 		JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO protein:decreased expression:plasma (human)
associated with Heart Failure; protein:increased expression:plasma (human) 		RGD PMID:23396398 PMID:20685687 RGD:7243186, RGD:7244134 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association 		ISO DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human) 		RGD PMID:9456365 PMID:9857918 RGD:1601152, RGD:1566499 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 ISO DNA:missense mutation:cds:V140I (rs37369)(human) RGD PMID:24834905 RGD:329961320 NCBI chr 2:61,063,416...61,104,828
Ensembl chr 2:61,063,419...61,105,090 		JBrowse link
G Apoa4 apolipoprotein A4 susceptibility
no_association 		ISO DNA:missense mutation:cds:p.T347S (human) RGD PMID:12676816 PMID:9013087 RGD:1578411, RGD:5685683 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164 		JBrowse link
G Apob apolipoprotein B ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Early-onset coronary artery disease 		CTD
ClinVar		 PMID:17658632 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Apoc2 apolipoprotein C2 susceptibility ISO RGD PMID:7590197 RGD:1601205 NCBI chr 1:88,457,397...88,462,365
Ensembl chr 1:88,457,396...88,463,438 		JBrowse link
G Apoc3 apolipoprotein C3 no_association
susceptibility 		ISO DNA:polymorphism:promoter:-482C>T
ClinVar Annotator: match by term: Coronary heart disease
associated with Diabetes Mellitus, Non-Insulin-Dependent 		ClinVar
RGD		 PMID:9536098 PMID:11060345 PMID:17576681 PMID:19074352 PMID:20097930 More... RGD:1601224, RGD:2306754 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679 		JBrowse link
G Apoe apolipoprotein E onset ISO DNA:polymorphisms, haplotype:promoter, cds:g.-219G>T, p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism 		RGD
CTD		 PMID:10736278 PMID:11862316 PMID:11862316 RGD:1578479, RGD:1578479 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Ccdc92 coiled-coil domain containing 92 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:37,457,676...37,484,080
Ensembl chr12:37,457,068...37,484,327 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 resistance ISO DNA:polymorphisms:multiple (human) RGD PMID:16055130 RGD:1581176 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cd14 CD14 molecule ISO protein:increased expression:monocyte RGD PMID:10831941 RGD:2314175 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd36 CD36 molecule ISO mRNA:increased expression:monocyte
ClinVar Annotator: match by term: CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 7 | ClinVar Annotator: match by term: Coronary heart disease, susceptibility to, 7
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD
RGD		 PMID:25741868 PMID:28960434 PMID:33116287 PMID:18067591 RGD:6893507 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd40lg CD40 ligand treatment IDA RGD PMID:23819214 RGD:7248750 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar PMID:25741868 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO DNA:polymorphism: :p.V249I (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary heart disease, susceptibility to, 1 		CTD
OMIM
ClinVar
RGD		 PMID:25741868 PMID:11532900 RGD:4891901 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983 		JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD PMID:10488959 RGD:1580275 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 resistance ISO DNA:polymorphism:promoter:-50G>T (human) RGD PMID:17429317 RGD:1625377 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042 		JBrowse link
G Dab2ip DAB2 interacting protein ISO DNA:SNP:CDS:rs7025486 (human) RGD PMID:21444365 RGD:401938618 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:39,312,745...39,483,730 		JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 6:144,982,130...145,298,523
Ensembl chr 6:144,973,797...145,298,692 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:16595607 RGD:1580981 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17367797 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G F12 coagulation factor XII ISO protein:decreased activity:: RGD PMID:18021303 RGD:11041785 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664 		JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO RGD PMID:11391716 RGD:1581030 NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:15451784 RGD:2315870 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO DNA:SNP: :rs9939609 (human) RGD PMID:26555680 RGD:11555922 NCBI chr19:31,456,749...31,865,011
Ensembl chr19:31,522,293...31,864,957 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO ClinVar Annotator: match by term: Early-onset coronary artery disease ClinVar PMID:1945893 PMID:3198117 PMID:6805883 PMID:7803800 PMID:8244337 More... NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:serum RGD PMID:16772340 RGD:2315604 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050 		JBrowse link
G Glul glutamate-ammonia ligase ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs10911021 (human) RGD PMID:23982368 RGD:401794410 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:14592833 RGD:1580433 NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,829,832...55,854,560 		JBrowse link
G Gp6 glycoprotein VI treatment
exacerbates 		ISO protein:increased expression:venous blood, platelet (human)
DNA:hypomethylation:promoter 		RGD PMID:17105818 PMID:20049463 PMID:31783053 RGD:401794440, RGD:401824649, RGD:401824645 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:78,508,468...78,535,374 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase disease_progression ISO RGD PMID:15809366 RGD:5508474 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:15869055 RGD:1598404 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnf1a HNF1 homeobox A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755 		JBrowse link
G Hp haptoglobin severity ISO RGD PMID:16673012 RGD:1626344 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNPs: : -110A>C (rs1008438), 190G>C (rs1043618) (human) RGD PMID:19333379 RGD:7257652 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:12059985 RGD:1624217 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit ISO RGD PMID:15521962 RGD:1626121 NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO RGD PMID:15521962 RGD:1626121 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO ClinVar Annotator: match by term: Early-onset coronary artery disease ClinVar PMID:1945893 PMID:3198117 PMID:6805883 PMID:7803800 PMID:8244337 More... NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:157,367,639...157,392,757 		JBrowse link
G Il18 interleukin 18 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar PMID:25741868 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta ISO DNA:polymorphism RGD PMID:15379752 RGD:1626636 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Irf8 interferon regulatory factor 8 susceptibility ISO DNA:SNPs:intron 4, intron 2: (rs925994,rs10514610) (human) RGD PMID:23661672 RGD:329902076 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062 		JBrowse link
G Irs1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:9684730 RGD:1582306 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509 		JBrowse link
G Itgam integrin subunit alpha M exacerbates ISO protein:increased expression:monocyte (human) RGD PMID:20876457 RGD:329901842 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:polymorphism:exon RGD PMID:10583927 RGD:5128478 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800 		JBrowse link
G Kalrn kalirin, RhoGEF kinase ISO ClinVar Annotator: match by term: Coronary heart disease, susceptibility to, 5 ClinVar PMID:17357071 PMID:25741868 NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329 		JBrowse link
G Kat2b lysine acetyltransferase 2B severity ISO DNA:snp:promoter:g.-2481G>C (human) RGD PMID:21062767 RGD:9590309 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 no_association ISO RGD PMID:12964027 RGD:1581699 NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531 		JBrowse link
G Kdr kinase insert domain receptor ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Ldlr low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Early-onset coronary artery disease 		CTD
ClinVar		 PMID:9430375 PMID:9712531 PMID:10422804 PMID:11810272 PMID:11845603 More... NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lepr leptin receptor onset ISO DNA:SNP: C>T (rs6656451) (human) RGD PMID:29848931 RGD:401799677 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Lgals2 galectin 2 susceptibility ISO RGD PMID:17040205 RGD:1581853 NCBI chr 7:112,283,630...112,290,228
Ensembl chr 7:112,282,822...112,285,392 		JBrowse link
G Lipc lipase C, hepatic type susceptibility ISO associated with Obesity and Diabetes; DNA:transition:promoter:-514C>T (human) RGD PMID:16570154 RGD:2308824 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285 		JBrowse link
G Lpl lipoprotein lipase IEP
ISO 		ClinVar Annotator: match by term: Coronary heart disease ClinVar
RGD		 PMID:8199176 PMID:8541837 PMID:8872057 PMID:10364086 PMID:10517255 More... RGD:13794381 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO RGD PMID:15121769 RGD:1581911 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196 		JBrowse link
G Maco1 macoilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 5:152,296,107...152,358,684
Ensembl chr 5:152,296,558...152,358,684 		JBrowse link
G Mb myoglobin severity ISO RGD PMID:15976963 RGD:1582388 NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958 		JBrowse link
G Mgp matrix Gla protein susceptibility ISO RGD PMID:16973975 RGD:1582502 NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859 		JBrowse link
G Mif macrophage migration inhibitory factor IEP coronary occlusion; mRNA:increased expression:myocardium RGD PMID:20367970 RGD:4890973 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mlxip MLX interacting protein susceptibility ISO DNA:SNP:3'utr: (rs4758685) (human) RGD PMID:23840567 RGD:401794443 NCBI chr12:38,789,404...38,853,059
Ensembl chr12:38,789,404...38,853,059 		JBrowse link
G Mlxipl MLX interacting protein-like susceptibility ISO DNA:SNP: (rs35493868); in younger than 55 years of age RGD PMID:29848931 RGD:401799677 NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660 		JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:14499230 RGD:1582537 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp3 matrix metallopeptidase 3 susceptibility ISO ClinVar Annotator: match by term: Coronary heart disease, susceptibility to, 6 | ClinVar Annotator: match by term: MMP3-related condition
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD		 PMID:7727178 PMID:8662692 PMID:9699891 PMID:10190398 PMID:10351963 More... NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16792904 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105 		JBrowse link
G Mttp microsomal triglyceride transfer protein susceptibility ISO DNA:polymorphism:promoter:-493G>T RGD PMID:15136504 RGD:1625487 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650 		JBrowse link
G Myh15 myosin, heavy chain 15 ISO DNA:snp:exon:EX28T>C rs3900940 (human) RGD PMID:18073581 RGD:2317145 NCBI chr11:65,084,666...65,226,010
Ensembl chr11:65,084,467...65,245,716 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 exacerbates ISO mRNA:decreased expression:peripheral blood mononuclear cell (human)
mRNA:increased expression:peripheral blood mononuclear cell (human) 		RGD PMID:16252156 PMID:19211025 RGD:401827902, RGD:401850788 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 susceptibility ISO DNA:SNP:intron:c.2222A>G (rs2074458) (human) RGD PMID:17761941 RGD:401851037 NCBI chr 7:9,534,530...9,536,990
Ensembl chr 7:9,533,811...9,536,990 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 susceptibility ISO DNA:missense mutation, nonsense mutations:cds:p.R46L, p.Y142X, p.C679X (human) RGD PMID:16554528 RGD:1581000 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar PMID:8532023 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 no_association
susceptibility 		ISO DNA:SNP:intron 3: (rs12526453) (human)
associated with type 2 diabetes mellitus;DNA:SNP:intron: (rs12526453) (human) 		RGD PMID:28287809 PMID:22152955 RGD:401901081, RGD:11055500 NCBI chr17:21,769,006...22,246,227
Ensembl chr17:21,768,662...22,244,586 		JBrowse link
G Pla2g7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21356620 PMID:15699277 RGD:6482780 NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:1730212 PMID:9181759 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Pltp phospholipid transfer protein susceptibility ISO protein:increased expression:serum (human) RGD PMID:14695459 RGD:1581038 NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:173,994,162...174,012,505 		JBrowse link
G Pon1 paraoxonase 1 severity
no_association 		ISO protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.Q192R (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human) 		CTD
RGD		 PMID:16353344 PMID:16882531 PMID:19005291 PMID:15214960 PMID:9215303 RGD:2313267, RGD:8547675, RGD:1580201 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Pon2 paraoxonase 2 susceptibility ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:9443862 RGD:1580216 NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996 		JBrowse link
G Ppbp pro-platelet basic protein ISO associated with menopause; mRNA,protein:increased expression:peripheral blood mononuclear cell ,plasma RGD PMID:35734636 RGD:401794436 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299 		JBrowse link
G Rbp4 retinol binding protein 4 ISO protein:increased expression:blood plasma (human) RGD PMID:23584360 RGD:329845574 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898 		JBrowse link
G Retn resistin ISO protein:increased expression:blood RGD PMID:17175295 RGD:7207156 NCBI chr12:6,508,653...6,511,115
Ensembl chr12:6,508,801...6,511,116 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 ameliorates ISO DNA:SNP:cds:rs6010620|rs4809324 (human) RGD PMID:30623606 RGD:152985693 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO RGD PMID:15967843 RGD:1580004 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Selp selectin P ISO protein:altered expression:serum RGD PMID:11597943 RGD:1580074 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987 		JBrowse link
G Serpinf2 serpin family F member 2 ISO protein:increased expression:blood RGD PMID:15771120 RGD:1625529 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225 		JBrowse link
G Tert telomerase reverse transcriptase ISO ClinVar Annotator: match by term: Coronary artery disease, susceptibility to ClinVar PMID:16890917 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Thbd thrombomodulin ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:17200788 RGD:2312456 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16549638 NCBI chr 1:191,932,969...191,935,490 JBrowse link
G Vwf von Willebrand factor ISO RGD PMID:11864703 RGD:1580647 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 4:59,957,402...59,979,336
Ensembl chr 4:59,957,402...59,979,336 		JBrowse link
acute myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap17 Rho GTPase activating protein 17 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 1:187,238,675...187,328,093
Ensembl chr 1:187,238,380...187,327,936 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G C3 complement C3 ISO RGD PMID:26476955 RGD:11552746 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO mRNA:decreased expression:blood: RGD PMID:27746059 RGD:13524557 NCBI chr10:93,183,410...93,245,470
Ensembl chr10:93,183,410...93,245,470 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:30371213 RGD:329845516 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 ameliorates IEP
ISO 		mRNA,protein:decreased expression:heart RGD PMID:30144448 PMID:30144448 RGD:407571674, RGD:407571674 NCBI chr 7:24,630,233...24,665,270
Ensembl chr 7:24,630,238...24,664,354 		JBrowse link
G Dsc2 desmocollin 2 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IEP RGD PMID:23054911 RGD:405650598 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO mRNA:increased expression:blood RGD PMID:35693610 RGD:329901852 NCBI chr19:31,456,749...31,865,011
Ensembl chr19:31,522,293...31,864,957 		JBrowse link
G Gata5 GATA binding protein 5 susceptibility ISO DNA:SNPs:promoter:rs80197101, rs77067995 (human) RGD PMID:33684162 RGD:155260335 NCBI chr 3:187,796,140...187,804,327
Ensembl chr 3:187,796,142...187,804,327 		JBrowse link
G Gp6 glycoprotein VI ameliorates
sexual_dimorphism 		ISO DNA:missense mutation:CDS:p.S219P (rs1613662) (human)
DNA:missense mutation:intron 1, intron 5: (rs1671207, rs11084382) (human) 		RGD PMID:20227257 PMID:20227257 RGD:401794138, RGD:401794138 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:78,508,468...78,535,374 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:increased expression:plasma RGD PMID:28374671 RGD:401827832 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment
ameliorates 		IEP RGD PMID:26591365 PMID:32068187 RGD:13792778, RGD:267358468 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates IMP RGD PMID:31755219 RGD:213230161 NCBI chr 1:207,160,175...207,162,851 JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO ClinVar Annotator: match by term: Acute myocardial infarction ClinVar NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
G Ifng interferon gamma ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:157,367,639...157,392,757 		JBrowse link
G Il10 interleukin 10 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il17a interleukin 17A ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il1b interleukin 1 beta ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il33 interleukin 33 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Il4 interleukin 4 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itgam integrin subunit alpha M treatment ISO RGD PMID:21238619 RGD:329901664 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Kif6 kinesin family member 6 ISO DNA:SNP: :p.W719R (rs20455) (human) RGD PMID:20044086 RGD:243048455 NCBI chr 9:18,573,925...18,870,789
Ensembl chr 9:18,573,789...18,870,729 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP RGD PMID:30144448 RGD:407571674 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850 		JBrowse link
G Mir126a microRNA 126a disease_progression ISO RGD PMID:36523365 PMID:32595526 RGD:401851047, RGD:401851053 NCBI chr 3:29,813,150...29,813,267 JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mir17 microRNA 17 treatment IMP RGD PMID:29536180 RGD:329403057 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:98,587,848...98,587,931 		JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma
RNA:decreased expression:serum 		RGD PMID:31866771 PMID:32595526 RGD:21081515, RGD:401851053 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:29689569 RGD:25823140 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:65,151,383...65,151,492 		JBrowse link
G Mir320a microRNA 320a ISO RGD PMID:29990866 RGD:155882565 NCBI chr15:51,926,088...51,926,169
Ensembl chr15:51,926,088...51,926,169 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674 		JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 ameliorates IEP associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 2:117,447,605...117,461,943
Ensembl chr 2:117,447,035...117,461,590 		JBrowse link
G Pf4 platelet factor 4 treatment IEP RGD PMID:29407168 RGD:329901925 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392 		JBrowse link
G Plcg1 phospholipase C, gamma 1 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050 		JBrowse link
G Ppbp pro-platelet basic protein treatment IEP RGD PMID:29407168 RGD:329901925 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299 		JBrowse link
G Pten phosphatase and tensin homolog ameliorates IEP
ISO 		mRNA:decreased expression:heart left ventricle (rat)
RNA:increased expression:serum 		RGD PMID:26973267 PMID:32595526 PMID:29990866 RGD:11526378, RGD:401851053, RGD:155882565 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Rhoa ras homolog family member A ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Rit2 Ras-like without CAAX 2 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr18:22,839,914...23,196,137
Ensembl chr18:22,839,915...23,269,823 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ameliorates IEP associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:158,547,689...158,569,667 		JBrowse link
G Serping1 serpin family G member 1 ISO
IEP 		mRNA:increased expression:heart RGD PMID:26476955 PMID:26476955 RGD:11552746, RGD:11552746 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717 		JBrowse link
G Sqstm1 sequestosome 1 treatment IEP RGD PMID:30144448 RGD:407571674 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Tbx1 T-box transcription factor 1 treatment IEP RGD PMID:27422448 RGD:155882497 NCBI chr11:95,913,610...95,923,392
Ensembl chr11:95,913,610...95,923,392 		JBrowse link
G Tnf tumor necrosis factor ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr17:56,644,397...56,811,155
Ensembl chr17:56,644,397...56,810,745 		JBrowse link
anterolateral myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO protein:increased expression:aortic root, coronary sinus, plasma (human) RGD PMID:12581682 RGD:8661757 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Serpine1 serpin family E member 1 disease_progression ISO protein:decreased expression, decreased activity:heart: RGD PMID:12615902 PMID:12615902 RGD:13208541, RGD:13208541 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:21489814 RGD:155260371 NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565 		JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:11,773,475...12,007,271 		JBrowse link
Cardiogenic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19337937 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21062213 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
coronary aneurysm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with Mucocutaneous Lymph Node Syndrome;protein:increased expression:serum RGD PMID:22683371 RGD:8694456 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15548583 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18084290 NCBI chr 1:91,628,606...91,650,182
Ensembl chr 1:91,628,608...91,653,350 		JBrowse link
G Mill1 MHC I like leukocyte 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10899738 NCBI chr 1:87,500,591...87,526,983
Ensembl chr 1:87,500,676...87,526,981 		JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:12103254 RGD:1582363 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478 		JBrowse link
coronary artery disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD
GAD		 PMID:11086027 PMID:15118671 RGD:1600951, RGD:1331525 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 ISO DNA:nonsense mutation:exon:p.R1141X (3421C>T) (human) RGD PMID:12176944 RGD:11038788 NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 PMID:11138003 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Premature coronary artery atherosclerosis 		CTD
ClinVar		 PMID:11099417 PMID:25741868 NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 3:30,560,172...30,604,758 JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :41A>G, 734C>T, IVS4-57_58ins48bp RGD PMID:16195894 RGD:1601112 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:14989558 PMID:12975417 PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Acp1 acid phosphatase 1 ISO RGD PMID:19246900 RGD:2313179 NCBI chr 6:53,233,937...53,249,576
Ensembl chr 6:53,233,948...53,251,959 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:99,584,529...99,624,132
Ensembl chr 8:99,584,529...99,624,132 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing susceptibility ISO protein:decreased expression:adipose tissue
associated with type 2 diabetes mellitus; DNA:SNP: (rs2241766) +45T>G(human) 		RGD PMID:17878891 PMID:27218147 RGD:5686802, RGD:329956419 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Adrb3 adrenoceptor beta 3 no_association ISO DNA:missense mutation:cds:p.W64R (human)
DNA:missense mutation:cds:p.W64R rs4994 (human) 		RGD PMID:9126344 PMID:11229427 RGD:1559325, RGD:5684412 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378986 NCBI chr17:23,113,578...23,199,616
Ensembl chr17:23,135,809...23,216,622 		JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO DNA:polymorphism:cds:p.G82S (human)
associated with Mucocutaneous Lymph Node Syndrome 		RGD PMID:20668462 PMID:22337222 RGD:6767569, RGD:8695960 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility ISO DNA:polymorphism:3' utr:1166A>C RGD
GAD		 PMID:12975417 PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 ISO DNA:missense mutation:cds:rs37369, rs16899974 (human) RGD PMID:30284143 RGD:329961317 NCBI chr 2:61,063,416...61,104,828
Ensembl chr 2:61,063,419...61,105,090 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:SNPs RGD PMID:17062776 PMID:17062776 RGD:1625792, RGD:1625792 NCBI chr11:91,625,975...91,632,583
Ensembl chr11:91,625,975...91,634,039 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:18054314 RGD:5509083 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO DNA:snps:multiple (human) RGD PMID:19596330 RGD:2313883 NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 susceptibility ISO DNA:SNP:exon 2:34C>T (human) RGD PMID:11028479 RGD:329349360 NCBI chr 2:193,287,219...193,308,446
Ensembl chr 2:193,287,265...193,308,443 		JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681 		JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr20:5,965,421...6,118,875
Ensembl chr20:5,965,028...6,118,875 		JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:12714198 NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit ISO DNA:SNP:CDS:p.F217L (rs1047552) (human) RGD PMID:18987747 RGD:13703124 NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:76,310,380...76,331,428 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27135400 PMID:2128269 PMID:15118671 RGD:1601188, RGD:1331525 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa2 apolipoprotein A2 ISO protein:decreased expression:serum RGD PMID:17923573 RGD:2313956 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Apoa5 apolipoprotein A5 no_association ISO DNA:polymorphism:promoter:-1131T>C (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-1131T>C, c.56C>G (human) 		CTD
RGD		 PMID:24097064 PMID:15177130 PMID:15306190 RGD:2313322, RGD:1578412 NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507 		JBrowse link
G Apob apolipoprotein B no_association ISO DNA:SNP:CDS:rs1042031 (human) RGD
GAD		 PMID:9585673 PMID:28167353 PMID:15118671 PMID:1732399 RGD:1578418, RGD:329901772, RGD:1331525, RGD:1578417 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Apoc3 apolipoprotein C3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24097064 PMID:14709372 PMID:15118671 PMID:15059615 RGD:1578443, RGD:1331525, RGD:1626412 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679 		JBrowse link
G Apoe apolipoprotein E susceptibility ISO
IMP 		DNA:snp, missense mutation:promoter, cds:g.-219G>T, p.C112R (human)
associated with Diabetes Mellitus, Non-Insulin Dependent;DNA:SNP:promoter:-219G>T (human)
DNA:missense mutation:cds:p.C112R (human) 		RGD
GAD		 PMID:14563588 PMID:28808185 PMID:15118671 PMID:15059615 PMID:12860263 RGD:1580039, RGD:13703132, RGD:1331525, RGD:1626412, RGD:1578449 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Apom apolipoprotein M susceptibility ISO DNA:SNP:promoter:g.-778T>C(rs805296)(human) RGD PMID:17674965 RGD:2314241 NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218 		JBrowse link
G Ar androgen receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Arhgap31 Rho GTPase activating protein 31 susceptibility ISO associated with nicotine dependence;DNA:SNP: (rs10934490) (human) RGD PMID:19706030 RGD:329970276 NCBI chr11:75,544,176...75,657,087
Ensembl chr11:75,544,040...75,661,076 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904 		JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17852836 RGD:2306777 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760 		JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO DNA:SNP: :rs12732361(human), associated with male. RGD PMID:27461004 RGD:14398490 NCBI chr13:60,964,127...61,397,044
Ensembl chr13:60,966,100...61,397,039 		JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO associated with Mucocutaneous Lymph Node Syndrome; DNA:SNP: :rs 2395158(human) RGD PMID:19882345 RGD:9685030 NCBI chr20:4,492,100...4,505,932
Ensembl chr20:4,492,111...4,505,932 		JBrowse link
G C5h1orf167 similar to human chromosome 1 open reading frame 167 ISO DNA:SNP: :rs56001051(human) RGD PMID:31175347 RGD:14696712 NCBI chr 5:163,770,495...163,788,791 JBrowse link
G Carf calcium responsive transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 9:68,996,419...69,046,480
Ensembl chr 9:68,996,250...69,046,479 		JBrowse link
G Cbs cystathionine beta synthase ISO CBS variant c.844ins68 RGD PMID:12855221 RGD:1600626 NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO 		protein:increased expression:myocardium (rat)
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (human) 		CTD
RGD		 PMID:11500196 PMID:16934270 PMID:16297799 PMID:9537339 RGD:8549513, RGD:8549577 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:16620281 RGD:11081161 NCBI chr12:26,745,972...26,750,924 JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:12742282 RGD:5508477 NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12426226 RGD:1581178 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:heart (rat) RGD PMID:17449418 RGD:4890438 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cd14 CD14 molecule no_association ISO DNA:SNP:promoter RGD PMID:18157711 RGD:2314154 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd36 CD36 molecule ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd40lg CD40 ligand ISO
IEP 		protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome;DNA:SNP: :rs4810485 (human)
protein:increased expression:coronary artery, serum
associated with Kidney Failure, Chronic 		CTD
RGD		 PMID:16368305 PMID:17635572 PMID:22645426 PMID:23819214 PMID:16494885 RGD:2314209, RGD:8547776, RGD:7248750, RGD:7248436 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cdh5 cadherin 5 ISO RGD PMID:14695457 RGD:1598391 NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104008 PMID:34961328 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855 		JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:31358993 NCBI chr 5:159,409,900...159,420,282
Ensembl chr 5:159,409,899...159,426,208 		JBrowse link
G Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 2:198,717,333...198,741,689
Ensembl chr 2:198,717,896...198,741,581 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:17627189 RGD:4892665 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825 		JBrowse link
G Clcn6 chloride voltage-gated channel 6 susceptibility ISO DNA:SNP: :rs3737964(human) RGD PMID:26740945 RGD:14696742 NCBI chr 5:163,715,593...163,748,301
Ensembl chr 5:163,717,439...163,748,198 		JBrowse link
G Clu clusterin ISO associated with Mucocutaneous Lymph Node Syndrome;protein:decreased expression:plasma RGD PMID:20711835 RGD:9068393 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cpe carboxypeptidase E severity ISO DNA:SNPs:CDS:intron 4, exon 4 (A2925G, G2855A) (human) RGD PMID:18080843 RGD:405650688 NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524 		JBrowse link
G Crp C-reactive protein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:24868163 PMID:19615354 RGD:2313344 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Cst3 cystatin C ISO protein:increased expression:serum (human) RGD PMID:17983622 RGD:2314352 NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937 		JBrowse link
G Cubn cubilin susceptibility ISO DNA:SNP,haplotypes:intron: (rs2291521)G>A (human) RGD PMID:33004870 RGD:329901841 NCBI chr17:81,293,619...81,501,694
Ensembl chr17:81,293,619...81,501,694 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD
GAD		 PMID:14709372 PMID:15118671 RGD:1578443, RGD:1331525 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 ISO DNA:SNP:CDS:rs10741657 (human) RGD PMID:25003556 RGD:401901077 NCBI chr 1:178,166,984...178,232,191
Ensembl chr 1:178,219,704...178,232,423 		JBrowse link
G Dab2ip DAB2 interacting protein onset ISO DNA:SNP:CDS:rs7025486 (human) RGD PMID:30595311 RGD:401938617 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:39,312,745...39,483,730 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 ISO DNA:missense mutation:cds:rs997251 (human) RGD PMID:30284143 RGD:329961317 NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626 		JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent ISO CTD Direct Evidence: marker/mechanism CTD PMID:17267746 NCBI chr20:3,766,115...3,769,161
Ensembl chr20:3,766,120...3,769,183 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO protein:increased expression:smooth muscle cell,macrophage RGD PMID:10973835 PMID:8994440 RGD:1580909, RGD:7244168 NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719 		JBrowse link
G Edn1 endothelin 1 treatment
severity 		ISO
IMP 		protein:increased expression:atherosclerotic lesions (human)
associated with Hypertension;DNA:missense mutation:cds:p.L198N (human) 		RGD PMID:7968078 PMID:11927217 PMID:18923236 RGD:4144886, RGD:8662294, RGD:8661705 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Eng endoglin severity ISO protein:increased expression:plasma (human) RGD PMID:21667051 RGD:7248776 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:14732757 RGD:1580982 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:25245553 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:SNP: :rs13181(human) RGD PMID:27566080 RGD:12880440 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9396482 PMID:20559769 PMID:16159931 RGD:1580335 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20559769 PMID:16099331 RGD:1581014 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G F2 coagulation factor II, thrombin treatment ISO RGD PMID:14961168 RGD:10449426 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:plasma (human)
DNA:polymorphisms:cds:R353Q (human) 		RGD PMID:10599031 PMID:8522401 PMID:11334615 RGD:2312400, RGD:2312408, RGD:2312397 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738 		JBrowse link
G Fabp2 fatty acid binding protein 2 ISO associated with Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:15059615 RGD:1626412 NCBI chr 2:213,724,629...213,728,686
Ensembl chr 2:213,724,629...213,728,686 		JBrowse link
G Fcgr2a Fc gamma receptor 2A ISO DNA:polymorphism: :p.H131R (human) RGD PMID:20973705 RGD:5147917 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394 		JBrowse link
G Fcgr3a Fc gamma receptor 3A susceptibility ISO DNA:SNP:exon:p.F158V (rs396991)(human) RGD PMID:15910853 RGD:5508464 NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:143,746,945...143,756,181 		JBrowse link
G Fgb fibrinogen beta chain ISO RGD PMID:8565160 RGD:1580382 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:14585103 RGD:2315879 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO DNA:SNP: :rs9939609 (human)
DNA:SNP:intron:rs9939609 (human) 		RGD PMID:24622111 PMID:28167353 RGD:329812039, RGD:329901772 NCBI chr19:31,456,749...31,865,011
Ensembl chr19:31,522,293...31,864,957 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 1:143,757,389...143,770,430
Ensembl chr 1:143,757,391...143,773,497 		JBrowse link
G Gck glucokinase susceptibility ISO DNA:SNP:promoter:-30G>A (human) RGD PMID:15173029 RGD:2301876 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gfod1 Gfo/Idh/MocA-like oxidoreductase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr17:21,606,090...21,710,922
Ensembl chr17:21,605,415...21,710,920 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:106,027,918...106,043,653
Ensembl chr 4:106,027,912...106,043,923 		JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15059615 RGD:1626412 NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216 		JBrowse link
G Gnb3 G protein subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16141801 NCBI chr 4:159,325,741...159,331,443
Ensembl chr 4:159,325,742...159,331,445 		JBrowse link
G Gp6 glycoprotein VI treatment ISO protein:increased expression:platelet (human) RGD PMID:18585516 RGD:401794134 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:78,508,468...78,535,374 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics
DNA:repeat:exon 		RGD PMID:16338763 PMID:12655278 RGD:1600708, RGD:1600677 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:increased expression:epicardial fat RGD PMID:21679057 RGD:401827169 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405 		JBrowse link
G Gsr glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics RGD PMID:16338763 RGD:1600708 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion 		RGD PMID:19102712 PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion 		RGD PMID:19102712 PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737 		JBrowse link
G H19 H19 imprinted maternally expressed transcript susceptibility ISO DNA:SNPs,haplotype:intron: (rs2735971,rs2839698,rs3024270) (human) RGD PMID:32454910 RGD:242905209 NCBI chr 1:207,160,175...207,162,851 JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr12:40,800,232...40,991,584
Ensembl chr12:40,843,770...40,991,798 		JBrowse link
G Hfe homeostatic iron regulator no_association ISO RGD PMID:12746412 RGD:1582673 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208 		JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:11669408 RGD:8548610 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hhipl1 HHIP-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 6:132,984,028...133,008,248
Ensembl chr 6:132,984,032...133,006,947 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:12742282 RGD:5508477 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmox1 heme oxygenase 1 no_association
susceptibility 		ISO DNA:repeat:promoter
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:12136229 PMID:14691581 PMID:12377749 PMID:12136229 RGD:1580470, RGD:1580454, RGD:1598401 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnf1a HNF1 homeobox A susceptibility ISO DNA:SNP:intron 1: (rs7310409) G>A (human)
DNA:SNP,haplotypes:intron: (rs55783344) C>T(human)
DNA:SNPs,haplotypes:multiple 		RGD PMID:25202455 PMID:33004870 PMID:28035729 RGD:329901832, RGD:329901841, RGD:329901837 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755 		JBrowse link
G Hp haptoglobin ISO protein:increased expression:serum RGD PMID:884791 RGD:1626363 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518 		JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:15266341 PMID:15965027 PMID:16024819 PMID:16410828 PMID:17179217 More... NCBI chr14:75,398,101...75,429,628
Ensembl chr14:75,398,026...75,436,848 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 sexual_dimorphism ISO associated with obesity;mRNA,protein:increased expression:multiple (human) RGD PMID:23009206 RGD:329901914 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 severity ISO RGD PMID:11222468 RGD:1624218 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Ica1l islet cell autoantigen 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 9:68,906,148...68,964,078
Ensembl chr 9:68,906,148...68,963,692 		JBrowse link
G Il10 interleukin 10 no_association
susceptibility 		ISO DNA:SNPs:promoter:-592C>A (rs1800872), -819C>T (rs1800871) (human)
DNA:SNP:promoter:-1082A>G (rs1800896) (human) 		RGD PMID:16460885 PMID:29525679 PMID:29525679 RGD:1598621, RGD:14975129, RGD:14975129 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il15 interleukin 15 ISO associated with Hypertension;protein:increased expression:serum RGD PMID:16109314 RGD:1626610 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il1b interleukin 1 beta ISO mRNA:increased expression:peripheral blood (human) RGD PMID:22780915 RGD:7175093 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO DNA:polymorphisms: :-27307T>A, -27614C>A (human) RGD PMID:20602249 RGD:5144241 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il6 interleukin 6 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human) RGD PMID:19368923 RGD:2307251 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825 		JBrowse link
G Irs1 insulin receptor substrate 1 ISO DNA:polymorphism:exon:G972R
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:10591678 PMID:10591678 RGD:1624974 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:15227729 RGD:1582294 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509 		JBrowse link
G Jcad junctional cadherin 5 associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 PMID:34961328 NCBI chr17:57,784,634...57,826,213
Ensembl chr17:57,784,634...57,826,183 		JBrowse link
G Kalrn kalirin, RhoGEF kinase susceptibility
onset
severity 		ISO DNA:SNP:intron: (rs9289231) T>G (human)
associated with nicotine dependence; DNA:SNPs:multiple
associated with type 2 diabetes mellitus;DNA:SNP:intron: (rs9289231) T>G (human)
DNA:SNP:intron: (rs9289231) (human) 		RGD PMID:30483314 PMID:19706030 PMID:27218147 PMID:25316661 RGD:329955537, RGD:329970276, RGD:329956419, RGD:11076452 NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr11:45,003,468...45,015,942
Ensembl chr11:45,014,406...45,016,168 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531 		JBrowse link
G Kif6 kinesin family member 6 sexual_dimorphism
no_association
treatment 		ISO DNA:SNP: :rs20455 (human)
associated with type 2 diabetes mellitus;DNA:SNP: :p.W719R (rs20455) (human) 		RGD PMID:18222354 PMID:25629058 PMID:21458191 PMID:26443250 PMID:26997531 More... RGD:243048446, RGD:243048454, RGD:243048451, RGD:11527801, RGD:243048449, RGD:243048447 NCBI chr 9:18,573,925...18,870,789
Ensembl chr 9:18,573,789...18,870,729 		JBrowse link
G Kl Klotho ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter: -G395>A (human) 		CTD
RGD		 PMID:12669274 PMID:16979405 PMID:16579981 RGD:1581721, RGD:1581723 NCBI chr12:5,326,003...5,367,016
Ensembl chr12:5,325,959...5,367,015 		JBrowse link
G Ldlr low density lipoprotein receptor no_association ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21378990 PMID:27135400 PMID:16459141 RGD:1581823 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:SNP:cds:p.Q223R(human) RGD PMID:27257426 RGD:21079462 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Lipa lipase A, lysosomal acid type ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 PMID:34961328 PMID:35590109 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740 		JBrowse link
G Lipc lipase C, hepatic type susceptibility
no_association 		ISO associated with Diabetes Mellitus, Insulin-Dependent; DNA:transition:promoter:-480C>T (human)
DNA:SNP,haplotypes: (rs17269397)A>G (human) 		RGD
GAD		 PMID:11916946 PMID:33004870 PMID:15118671 PMID:12689525 PMID:15099346 RGD:2308839, RGD:329901841, RGD:1331525, RGD:1600664, RGD:1600663 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285 		JBrowse link
G Lipg lipase G, endothelial type ISO RGD PMID:16354105 RGD:1580865 NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260 		JBrowse link
G Lmod1 leiomodin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116 		JBrowse link
G Lox lysyl oxidase IDA RGD PMID:12393934 RGD:1581886 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Lpl lipoprotein lipase ISO RGD PMID:8641022 RGD:1580537 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Lrp6 LDL receptor related protein 6 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:28492532 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716 		JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
onset 		ISO DNA:missense mutation:cds:p.R952Q (human) RGD PMID:18592168 PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:127,792,299...127,864,207 		JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15266304 PMID:15973460 RGD:1580414 NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533 		JBrowse link
G Lum lumican ISO RGD PMID:11890723 RGD:1582121 NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO associated with hypothyroidism;mRNA:decreased expression:venous blood (human) RGD PMID:32495070 RGD:155791451 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Mat2a methionine adenosyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645 		JBrowse link
G Mef2a myocyte enhancer factor 2a ISO RGD PMID:15811259 RGD:1580548 NCBI chr 1:130,258,083...130,392,819
Ensembl chr 1:130,260,339...130,392,162 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease 		CTD
ClinVar		 PMID:21378990 PMID:25741868 PMID:34961328 NCBI chr13:97,502,040...97,547,155
Ensembl chr13:97,494,275...97,543,587 		JBrowse link
G Mir1 microRNA 1 disease_progression ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr18:2,160,327...2,160,413 JBrowse link
G Mir126a microRNA 126a disease_progression
severity 		ISO miRNA:increased expression:blood plasma (human)
associated with Stable Angina, 		RGD PMID:25728840 PMID:27497911 RGD:11056497, RGD:401850779 NCBI chr 3:29,813,150...29,813,267 JBrowse link
G Mir133a1 microRNA 133a-1 ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr18:2,157,872...2,157,958 JBrowse link
G Mir145 microRNA 145 disease_progression ISO miRNA:decreased expression:artery wall (human) RGD PMID:25938589 RGD:11054026 NCBI chr18:57,369,983...57,370,070 JBrowse link
G Mir146a microRNA 146a susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: (rs2910164) (human)
miRNA:increased expression:peripheral blood mononuclear cell, plasma 		CTD
RGD		 PMID:20524934 PMID:26909569 PMID:31866771 RGD:329337364, RGD:21081515 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir146b microRNA 146b ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 1:255,144,860...255,144,947
Ensembl chr 1:255,144,860...255,144,947 		JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mir195 microRNA 195 ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr10:55,450,495...55,450,581
Ensembl chr10:55,450,495...55,450,581 		JBrowse link
G Mir208a microRNA 208a ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr15:32,395,552...32,395,634 JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma
miRNA:increased expression:blood plasma (human) 		RGD PMID:31866771 PMID:25728840 RGD:21081515, RGD:11056497 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mir214 microRNA 214 ISO miRNA:increased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752 		JBrowse link
G Mir223 microRNA 223 treatment ISO RGD PMID:25350775 RGD:11076984 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:65,151,383...65,151,492 		JBrowse link
G Mir30a microRNA 30a disease_progression ISO miRNA:increased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011 		JBrowse link
G Mir30e microRNA 30e ISO miRNA:increased expression:plasma, extracellular exosome (human) RGD PMID:30816508 RGD:401827150 NCBI chr 5:139,637,450...139,637,541
Ensembl chr 5:139,637,450...139,637,541 		JBrowse link
G Mir320a microRNA 320a disease_progression ISO miRNA:increased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr15:51,926,088...51,926,169
Ensembl chr15:51,926,088...51,926,169 		JBrowse link
G Mir423 microRNA 423 disease_progression ISO DNA:SNP: :rs6505162 (human)
miRNA:decreased expression:serum 		RGD PMID:30289085 PMID:32404537 RGD:158014893, RGD:158014898 NCBI chr10:62,412,272...62,412,350 JBrowse link
G Mlxipl MLX interacting protein-like susceptibility ISO DNA:SNPs,haplotypes: (rs3812316) (human)
DNA:SNP:cds: G771C, Q241H (rs381231)
DNA:SNP:cds: C771G, H241Q 		RGD PMID:21726544 PMID:19571538 PMID:25179879 RGD:401794579, RGD:401794582, RGD:401794581 NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660 		JBrowse link
G Mmp1 matrix metallopeptidase 1 severity ISO DNA:insertion, haplotype:promoter:g.-1607insG rs799750 (human) RGD PMID:15619398 PMID:17893005 RGD:1582527, RGD:7207049 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:10807873 RGD:1582366 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO DNA:insertion, haplotype:promoter:g.-1613insA rs3025058 (human)
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome 		CTD
RGD		 PMID:8662692 PMID:17893005 PMID:16100452 RGD:7207049, RGD:8693322 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility
treatment 		ISO
IEP 		RGD PMID:15191941 PMID:26261622 RGD:1582644, RGD:11344965 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:35590109 NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911 		JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:34961328 NCBI chr11:44,778,667...44,834,420
Ensembl chr11:44,781,554...44,834,962 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association
susceptibility 		ISO DNA:transition:cds:g.677C>T (human)
DNA:SNPs: (rs1801133, rs4846049) (Human) 		RGD PMID:15648053 PMID:24315498 PMID:12387655 RGD:1580579, RGD:401850782, RGD:6893453 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105 		JBrowse link
G Mylk myosin light chain kinase susceptibility ISO associated with nicotine dependence; DNA:SNP: (rs16834817) RGD PMID:19706030 RGD:329970276 NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO RGD PMID:17283255 RGD:1642340 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544 		JBrowse link
G Nat2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21572414 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304 		JBrowse link
G Nbeal1 neurobeachin-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 9:69,069,326...69,237,932
Ensembl chr 9:69,070,247...69,231,307 		JBrowse link
G Ngf nerve growth factor ISO RGD PMID:11935372 RGD:1580935 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:11935372 RGD:1580935 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305 		JBrowse link
G Nnmt nicotinamide N-methyltransferase severity ISO protein:increased expression:blood serum (human) RGD PMID:28174167 RGD:401793727 NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO DNA:polymorphisms: :p.G908R, 3020_3021insC (human) RGD PMID:21565239 RGD:5508725 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with Mucocutaneous Lymph Node Syndrome; protein:increased expression:neutrophil, monocyte RGD PMID:14764920 RGD:1580941 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:g.-786T>C (human)
DNA:snp:cds:c.894G>T (human) 		CTD
RGD		 PMID:10510054 PMID:14989558 PMID:17267746 PMID:19696404 PMID:8564837 More... RGD:7421529, RGD:7771578, RGD:7771567 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Nppa natriuretic peptide A ISO DNA:snp:cds:c.2238T>C (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP:exon: 2238T>C,rs5065 (human) 		RGD PMID:12514664 PMID:22170009 RGD:1579982, RGD:7247716 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18022110 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO associated with type 2 diabetes mellitus;mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:28871240 RGD:401850555 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:missense mutation:cds:p.N363S (human) RGD PMID:12623935 RGD:1580790 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase susceptibility ISO DNA:SNP,haplotype: :p.S326C (rs1052133) (human) RGD PMID:23368530 RGD:401827273 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 severity ISO DNA:snp:3' utr:T>C (human)
DNA:missense mutation:cds:p.K167N (human) 		RGD PMID:12810610 PMID:15562935 RGD:1580995, RGD:1580994 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598 		JBrowse link
G Pappa pappalysin severity ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11586954 PMID:16055491 RGD:1642327 NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361 		JBrowse link
G Parl presenilin associated, rhomboid-like susceptibility ISO DNA:missense mutation:cds:p.L262V (human) RGD PMID:18758826 RGD:12902623 NCBI chr11:94,097,559...94,124,915
Ensembl chr11:94,097,934...94,148,287 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Pdgfd platelet derived growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 PMID:34961328 NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:11,773,475...12,007,271 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 no_association ISO DNA:missense mutations:cds:p.N536S, p.G670R (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.L125V (human)
DNA:polymorphism:5' utr:g.53G>A (human) 		CTD
RGD		 PMID:28530674 PMID:11795274 PMID:10780329 PMID:12732396 RGD:2311656, RGD:6771225, RGD:1581010 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 susceptibility
sexual_dimorphism 		ISO CTD Direct Evidence: marker/mechanism
DNA:hypermethylation, hypomethylation:promoter, exon: (human)
DNA:SNP:exon: (rs4714955) (human)
DNA:SNPs:intron: (rs9381439, rs9349379) (human)
associated with familial hypercholesterolemia;DNA:SNP:intron: (rs12526453) (human)
DNA:SNP:intron:g.12903957A>G (rs9349379) (human)
DNA:SNP:intron:g.12903725A>G (rs9349379) (human) 		CTD
RGD		 PMID:21378990 PMID:22751097 PMID:26098115 PMID:34961328 PMID:31499127 More... RGD:401901251, RGD:401901243, RGD:401900688, RGD:401900687, RGD:401900135, RGD:401851919 NCBI chr17:21,769,006...22,246,227
Ensembl chr17:21,768,662...22,244,586 		JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr 4:174,215,527...174,583,378
Ensembl chr 4:174,215,527...174,581,705 		JBrowse link
G Pla2g7 phospholipase A2 group VII disease_progression
susceptibility 		ISO DNA:polymorphism: :p.A379V (human) RGD PMID:17070179 PMID:15115767 RGD:6482777, RGD:6482781 NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747 		JBrowse link
G Plpp3 phospholipid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:31377187 RGD:14981594 NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:117,173,516...117,194,594 		JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.Q192R (human)
CTD Direct Evidence: marker/mechanism|therapeutic
protein:increased activity:serum (human) 		CTD
RGD		 PMID:8675673 PMID:9215303 PMID:21629682 PMID:10729395 PMID:15785307 More... RGD:1580196, RGD:8547681, RGD:1580203 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Pon2 paraoxonase 2 severity ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:12454802 RGD:1580217 NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO DNA:snp:intron: (human) RGD PMID:16043164 RGD:1580228 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:decreased expression:carotid artery, macrophage, smooth muscle cell (human) RGD PMID:21709632 RGD:8552814 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit ISO mRNA:decreased expression:blood (human) RGD PMID:30015926 RGD:401901084 NCBI chr 1:190,823,447...190,830,247
Ensembl chr 1:190,823,486...190,830,168 		JBrowse link
G Prdm16 PR/SET domain 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35590109 NCBI chr 5:170,162,275...170,486,371
Ensembl chr 5:170,162,275...170,485,804 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:28492532 PMID:37198425 NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,744,588...10,985,939 		JBrowse link
G Procr protein C receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:164,711,636...164,718,989 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 2:198,710,427...198,715,001
Ensembl chr 2:198,705,839...198,714,997 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14642682 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human) RGD PMID:23460043 RGD:7242420 NCBI chr 1:176,942,901...176,946,034
Ensembl chr 1:176,943,102...176,946,034 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO DNA:SNP:exon 8:g.981C>T (human) RGD PMID:21676396 RGD:401965429 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO DNA: snp: cds: rs2476601 RGD PMID:21846984 RGD:6484553 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:194,045,746...194,103,209 		JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D ISO DNA:SNP:intron: (rs10115782) (human) RGD PMID:22216278 RGD:401976461 NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903 		JBrowse link
G Rbp4 retinol binding protein 4 sexual_dimorphism
susceptibility
severity
disease_progression 		ISO protein:increased expression:blood plasma (human)
DNA:SNP:intron: (rs7094671) (human)
associated with hypothyroidism;protein:increased expression:blood serum (human)
protein:increased expression:epicardial fat (human) 		RGD PMID:25437889 PMID:25479076 PMID:31278889 PMID:18854400 PMID:21645024 RGD:329845573, RGD:329845882, RGD:329845849, RGD:329845843, RGD:329845584 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898 		JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 2:198,753,673...198,769,411
Ensembl chr 2:198,753,675...198,769,365 		JBrowse link
G Sele selectin E susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:mutation: :p.S128R (human)
ClinVar Annotator: match by term: Coronary artery disease 		ClinVar
RGD		 PMID:25741868 PMID:17578587 RGD:2313596 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Selp selectin P ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987 		JBrowse link
G Serpina1 serpin family A member 1 ISO protein:increased expression:serum RGD PMID:7832094 RGD:1643149 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703 		JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:insertion:promoter: (human) RGD PMID:9484978 RGD:1580190 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Serpinf2 serpin family F member 2 ISO RGD PMID:9184412 RGD:1625532 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:40,392,633...40,414,335 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO mRNA:decreased expression:epicardial fat, subcutaneous adipose tissue (human) RGD PMID:21645024 RGD:329845584 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr11:44,799,787...44,802,233
Ensembl chr11:44,790,297...44,818,157 		JBrowse link
G Smad3 SMAD family member 3 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324 		JBrowse link
G Soat2 sterol O-acyltransferase 2 susceptibility ISO DNA:polymorphisms: :p.E41G, p.T734I, IVS4-57_-58ins48bp (human) RGD PMID:16195894 RGD:1601112 NCBI chr 7:135,160,424...135,173,521
Ensembl chr 7:135,160,402...135,173,513 		JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:10811593 RGD:1580853 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Sort1 sortilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:34961328 NCBI chr 2:198,609,466...198,690,481
Ensembl chr 2:198,612,148...198,690,481 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO In type 2 diabetic patients RGD PMID:21034455 RGD:6903271 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 susceptibility
disease_progression
severity 		ISO DNA:SNP, haplotype:: -36delG (human)
associated with type 2 diabetes mellitus; mRNA:increased expression:epicardial fat (human)
mRNA:decreased expression:blood serum (human) 		RGD PMID:12752570 PMID:28367087 PMID:31610782 RGD:401827912, RGD:401842368, RGD:401842364 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 disease_progression ISO associated with type 2 diabetes mellitus;mRNA:increased expression:epicardial fat (human) RGD PMID:28367087 RGD:401842368 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO GAD PMID:15118671 RGD:1331525 NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810 		JBrowse link
G Tbx2 T-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35590109 NCBI chr10:71,177,082...71,186,275
Ensembl chr10:71,177,082...71,186,275 		JBrowse link
G Tcf21 transcription factor 21 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: (rs12190287) (human) 		CTD
RGD		 PMID:21378990 PMID:22751097 PMID:26909569 RGD:329337364 NCBI chr 1:24,520,499...24,523,358
Ensembl chr 1:24,520,481...24,523,348 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO protein:increased expression:plasma RGD PMID:12814387 RGD:1601489 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991 		JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16890917 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Thbd thrombomodulin severity ISO RGD PMID:17012137 RGD:1601638 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582 		JBrowse link
G Tll1 tolloid-like 1 severity ISO associated with type 2 diabetes:DNA:SNP:CDS:rs1503298 (human) RGD PMID:21911782 RGD:155883159 NCBI chr16:30,275,492...30,476,673
Ensembl chr16:30,275,492...30,475,886 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20524934 PMID:15632890 RGD:1580736 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:15059615 RGD:1626412 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15926884 RGD:1620893 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A severity ISO RGD PMID:19845893 RGD:5131425 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnni3 troponin I3, cardiac type ISO RGD PMID:12221049 RGD:1580780 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Tp53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human) RGD PMID:29482350 RGD:14995930 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Traf6 TNF receptor associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
G Trib1 tribbles pseudokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064 NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:93,095,973...93,117,480 		JBrowse link
G Ttn titin ISO RGD PMID:12221049 RGD:1580780 NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965 		JBrowse link
G Vamp5 vesicle-associated membrane protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:105,982,004...105,993,247
Ensembl chr 4:105,982,009...105,993,247 		JBrowse link
G Vamp8 vesicle-associated membrane protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:106,000,570...106,011,081
Ensembl chr 4:106,000,570...106,011,073 		JBrowse link
G Vdr vitamin D receptor severity ISO DNA:SNP (human) RGD PMID:9761785 RGD:4889864 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:14668888 PMID:15937083 PMID:15754021 RGD:1580569 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin ISO protein:increased expression:monocyte RGD PMID:21938407 RGD:6480617 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vtn vitronectin ISO RGD PMID:15678274 RGD:1580816 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860 		JBrowse link
G Wdr12 WD repeat domain 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 9:68,969,547...68,996,811
Ensembl chr 9:68,969,547...68,996,811 		JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:11186893 RGD:1580824 NCBI chr16:65,466,552...65,602,951
Ensembl chr16:65,456,254...65,602,951 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 onset ISO DNA:polymorphism:: (rs1799782) (human) RGD PMID:24315498 RGD:401850782 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 susceptibility ISO DNA:SNP,haplotypes:exon 7: p.T241M (rs861539) (Human) RGD PMID:23368530 RGD:401827273 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822 		JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:59,957,402...59,979,336
Ensembl chr 4:59,957,402...59,979,336 		JBrowse link
G Zfyve21 zinc finger FYVE-type containing 21 ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr 6:136,695,132...136,715,601
Ensembl chr 6:136,694,908...136,715,601 		JBrowse link
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant, 1 | ClinVar Annotator: match by term: Coronary artery disease/myocardial infarction
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD		 PMID:14645853 PMID:15496429 PMID:15841183 PMID:25741868 NCBI chr 1:130,258,083...130,392,819
Ensembl chr 1:130,260,339...130,392,162 		JBrowse link
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2 ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:31,012,091...31,035,098
Ensembl chr 6:31,012,091...31,035,297 		JBrowse link
G Lrp6 LDL receptor related protein 6 ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD		 PMID:17332414 PMID:23703864 PMID:25741868 PMID:27713038 PMID:28492532 More... NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716 		JBrowse link
coronary artery vasospasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap9 Rho GTPase activating protein 9 ISO ClinVar Annotator: match by term: Coronary artery spasm 3, susceptibility to
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD		 PMID:19911011 NCBI chr 7:65,034,023...65,042,336
Ensembl chr 7:65,034,144...65,042,336 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: CORONARY ARTERY SPASM 1, SUSCEPTIBILITY TO 		CTD
ClinVar		 PMID:9737779 PMID:9894802 PMID:10359729 PMID:10475066 PMID:10510054 More... NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11810302 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
Coronary Occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 disease_progression ISO RGD PMID:26315408 RGD:14367880 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO mRNA:increased expression:heart: RGD PMID:21439970 RGD:7257651 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
coronary restenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:9236417 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:12138120 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Ahsp alpha hemoglobin stabilizing protein ISO mRNA:decreased expression:blood (human) RGD PMID:35144391 RGD:329961301 NCBI chr 1:192,310,306...192,315,943
Ensembl chr 1:192,310,244...192,315,942 		JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17275003 RGD:2306778 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760 		JBrowse link
G Cdh13 cadherin 13 IEP protein:increased expression:artery, smooth muscle cell RGD PMID:12376824 RGD:2293553 NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:plasma RGD PMID:14578618 RGD:1598500 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:14578618 RGD:1598500 NCBI chr  X:70,884,293...70,886,944
Ensembl chr  X:70,883,958...70,886,871 		JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO RGD PMID:14529396 RGD:1581036 NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579 		JBrowse link
G Hmox1 heme oxygenase 1 susceptibility ISO RGD PMID:16020495 PMID:14529548 RGD:1598402, RGD:1580472 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:11703955 RGD:1581185 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182 		JBrowse link
G Lox lysyl oxidase IDA RGD PMID:15218472 RGD:1581881 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:15583728 RGD:1582284 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:5' utr, exon:multiple (human) RGD PMID:15790942 RGD:1582150 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8662692 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IEP RGD PMID:21139058 RGD:9685362 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16489563 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IDA RGD PMID:7955204 RGD:10059621 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 IEP mRNA, protein:increased expression:carotid artery RGD PMID:12689918 RGD:1625501 NCBI chr16:27,822,055...27,830,012
Ensembl chr16:27,816,065...27,830,290 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 susceptibility ISO DNA:SNP:intron:c.2222A>G (rs2074458) (human) RGD PMID:17761941 RGD:401851037 NCBI chr 7:9,534,530...9,536,990
Ensembl chr 7:9,533,811...9,536,990 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:12114325 PMID:16373617 RGD:1581358, RGD:1581366 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16319143 PMID:16319143 RGD:1580322 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 ISO RGD PMID:14740296 RGD:1580742 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Ucp3 uncoupling protein 3 susceptibility ISO DNA:polymorphism:promoter:-55C>T (human) RGD PMID:17786284 RGD:2313513 NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:164,227,882...164,241,210 		JBrowse link
coronary stenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin ISO protein:decreased expression:plasma RGD PMID:19015606 RGD:2313942 NCBI chr  X:132,058,739...132,091,518
Ensembl chr  X:132,081,759...132,091,246 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 ISO DNA:SNP:CDS: (Rs6486205|rs10741657|rs2060793) RGD PMID:34262949 RGD:401901074 NCBI chr 1:178,166,984...178,232,191
Ensembl chr 1:178,219,704...178,232,423 		JBrowse link
G Edn1 endothelin 1 treatment ISO RGD PMID:10854676 RGD:8661796 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041 		JBrowse link
G Igf1 insulin-like growth factor 1 IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Itgav integrin subunit alpha V IDA RGD PMID:11922905 RGD:1582454 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 ISO protein:increased expression:coronary artery RGD PMID:32160773 RGD:243065232 NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:146,948,958...147,007,875 		JBrowse link
G Mdk midkine IDA RGD PMID:10683378 RGD:1299187 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743 		JBrowse link
G Myh7 myosin heavy chain 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO DNA:missense mutations:cds:p.L125V, p.S563N (human) RGD PMID:10571959 RGD:1598382 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 susceptibility ISO DNA:SNP::g.13011943A>G (rs9349379) (human) RGD PMID:22745674 RGD:401900726 NCBI chr17:21,769,006...22,246,227
Ensembl chr17:21,768,662...22,244,586 		JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:16782078 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15569000 RGD:1624167 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075 		JBrowse link
coronary thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp6 glycoprotein VI ISO DNA:missense mutation:CDS:c.13254T>C (human) RGD PMID:15306180 RGD:401793750 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:78,508,468...78,535,374 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8598867 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1452937 PMID:8172379 PMID:15301905 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
Hypertension Resistant to Conventional Therapy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion:cds: (human) RGD PMID:19279659 RGD:7495846 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: HYPERTENSION RESISTANT TO CONVENTIONAL THERAPY ClinVar PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 More... NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D susceptibility ISO associated with coronary artery disease;DNA:SNP:intron: (rs324498) (human) RGD PMID:30237584 RGD:401976431 NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903 		JBrowse link
intermediate coronary syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA:increased expression:ventricular myocardium (human)
mRNA:increased expression:myocardium 		RGD PMID:15131005 PMID:11451295 RGD:8142363, RGD:8548894 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Agt angiotensinogen ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:platelet RGD PMID:20467748 RGD:5509094 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:decreased expression:blood plasma (human) RGD PMID:20367977 RGD:5685646 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:16186425 RGD:4891111 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:9761079 RGD:9491780 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Edn1 endothelin 1 ISO associated with Coronary Artery Disease;protein:increased expression:coronary sinus, plasma (human) RGD PMID:14556009 RGD:8661755 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G F7 coagulation factor VII ISO protein:increased expression:plasma (human) RGD PMID:10653827 RGD:2312399 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18333374 RGD:5508458 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO RGD PMID:15104219 RGD:1582303 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509 		JBrowse link
G Itgam integrin subunit alpha M ameliorates ISO protein:decreased expression:neutrophil (human) RGD PMID:18043994 RGD:329901840 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160 		JBrowse link
G Mir126a microRNA 126a disease_progression ISO RGD PMID:32595526 RGD:401851053 NCBI chr 3:29,813,150...29,813,267 JBrowse link
G Mir21 microRNA 21 ISO RNA:decreased expression:serum RGD PMID:32595526 RGD:401851053 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:14675588 RGD:1582536 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Pappa pappalysin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954 NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:2382605 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Pten phosphatase and tensin homolog ISO RNA:increased expression:serum RGD PMID:32595526 RGD:401851053 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21162967 RGD:6219003 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987 		JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:8122184 RGD:11035255 NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643 		JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:15749180 RGD:1580784 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
Medial Coronary Sclerosis of Infancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO ClinVar Annotator: match by term: Coronary sclerosis, medial, of infancy ClinVar PMID:9536098 PMID:15940697 PMID:17576681 PMID:25741868 PMID:28492532 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044 		JBrowse link
myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 ISO ClinVar Annotator: match by term: Myocardial infarction ClinVar PMID:16563363 PMID:18239147 PMID:20474083 PMID:21846889 PMID:23739550 More... NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348 		JBrowse link
G Ace angiotensin I converting enzyme treatment
susceptibility 		ISO
IEP
IMP 		ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Myocardial Reperfusion Injury 		ClinVar
CTD
RGD		 PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... RGD:1331525, RGD:9685449, RGD:1558664, RGD:7829785, RGD:6893480 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Ace2 angiotensin converting enzyme 2 treatment IEP
IDA 		mRNA:increased expression:myocardium RGD PMID:15671045 PMID:23959549 RGD:1558664, RGD:9685449 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Acta2 actin alpha 2, smooth muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Acvr2a activin A receptor type 2A ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 3:53,614,143...53,701,933
Ensembl chr 3:53,614,171...53,701,941 		JBrowse link
G Acvr2b activin A receptor type 2B ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 8:128,016,589...128,056,193
Ensembl chr 8:128,016,526...128,048,171 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:15625312 RGD:9681751 NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390 		JBrowse link
G Add1 adducin 1 no_association ISO DNA:missense mutation:cds:p.G460W (human) RGD PMID:17082469 PMID:16420563 RGD:5147995, RGD:5148001 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression IEP RGD PMID:21326342 RGD:5686351 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Adipor1 adiponectin receptor 1 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr13:48,411,438...48,431,251
Ensembl chr13:48,411,826...48,431,255 		JBrowse link
G Adipor2 adiponectin receptor 2 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:154,172,567...154,231,666 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Adora3 adenosine A3 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 PMID:20132822 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686 		JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:12535806 RGD:1559314 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adrb1 adrenoceptor beta 1 ISO
IMP 		GAD
RGD		 PMID:15118671 PMID:17143192 RGD:1331525, RGD:7241557 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO
IEP 		DNA:polymorphisms: :p.G16R, p.Q27E, p.T164I
mRNA:decreased expression:heart 		RGD PMID:15520258 PMID:12400771 RGD:1601126, RGD:8548519 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility IEP
ISO 		mRNA:increased expression:left ventricle myocardium (rat)
DNA:polymorphism:promoter:-429T>C (human) 		RGD PMID:19910580 PMID:16728681 RGD:2325647, RGD:1625333 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agt angiotensinogen susceptibility IDA
ISO 		CTD Direct Evidence: marker/mechanism
associated with Coronary Artery Disease;DNA:polymorphism: :p.M235T (human)
associated with hypertension;DNA:polymorphism: :p.M235T 		CTD
RGD		 PMID:1668233 PMID:16413583 PMID:21167013 PMID:15118671 PMID:11393670 More... RGD:5129191, RGD:1331525, RGD:1566452, RGD:1601132 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association 		ISO
IEP 		DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human) 		RGD
GAD		 PMID:16061119 PMID:9652322 PMID:15118671 PMID:9857918 RGD:1601150, RGD:10047101, RGD:1331525, RGD:1566499 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein ISO protein:increased expression:plasma RGD PMID:19029462 RGD:2313810 NCBI chr11:91,625,975...91,632,583
Ensembl chr11:91,625,975...91,634,039 		JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 IEP RGD PMID:14732363 RGD:1580021 NCBI chr 2:223,825,930...223,849,477
Ensembl chr 2:223,825,931...223,849,994 		JBrowse link
G Ak1 adenylate kinase 1 treatment IEP RGD PMID:22229508 RGD:11100025 NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO
IDA 		protein:increased serine phosphorylation:platelet
protein:decreased serine phosphorylation:heart 		RGD PMID:20467748 PMID:20352476 RGD:5509094, RGD:10041035 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO DNA:missense mutation: :p.E487K (human) RGD PMID:12452318 RGD:2311152 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein no_association ISO DNA:snps:multiple (human) RGD
GAD		 PMID:14770184 PMID:15118671 PMID:19046748 RGD:1578317, RGD:1331525, RGD:2313891 NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038 		JBrowse link
G Ang angiogenin ISO RGD PMID:18462761 RGD:2325719 NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106 		JBrowse link
G Angpt1 angiopoietin 1 IEP mRNA, protein:decreased expression:myocardium RGD PMID:15364619 RGD:1626168 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696 		JBrowse link
G Angpt2 angiopoietin 2 IEP protein:increased expression:left ventricular wall, heart septum (rat) RGD PMID:16714360 RGD:1601493 NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239 		JBrowse link
G Anxa5 annexin A5 susceptibility
no_association 		ISO
IEP 		DNA:polymorphism: :-1C>T (human)
protein:altered localization:cardiac muscle cell, sarcolemma
protein:increased expression:plasma 		RGD PMID:12200370 PMID:16501019 PMID:8814351 PMID:16025836 RGD:2317542, RGD:2317541, RGD:2317543, RGD:1578384 NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 susceptibility ISO DNA:polymorphism:exon 5: G>A (human) RGD PMID:18712175 RGD:401827276 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Apoa1 apolipoprotein A1 treatment
no_association 		ISO
IEP 		DNA:polymorphisms RGD
GAD		 PMID:20176799 PMID:31734577 PMID:15118671 PMID:10428310 RGD:2325759, RGD:408418726, RGD:1331525, RGD:1578442 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa4 apolipoprotein A4 no_association
susceptibility 		ISO DNA:mutation:intron:IVS2 (human)
associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.Q360H (human) 		RGD
GAD		 PMID:10428310 PMID:7958503 PMID:15118671 RGD:1578442, RGD:5685678, RGD:1331525 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164 		JBrowse link
G Apob apolipoprotein B ISO GAD PMID:15118671 RGD:1331525 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Apoc3 apolipoprotein C3 no_association ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar
RGD		 PMID:25741868 PMID:10428310 PMID:15118671 RGD:1578442, RGD:1331525 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679 		JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:missense mutations, haplotypes:cds:p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations, haplotype:cds:p.C112R, p.C158R (human) 		CTD
RGD		 PMID:10587578 PMID:17217375 PMID:10090925 PMID:15118671 RGD:1601229, RGD:10449412, RGD:1331525 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Apoh apolipoprotein H ISO
IDA 		RGD PMID:15322656 PMID:12826288 RGD:2313985, RGD:10054111 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127 		JBrowse link
G Atg7 autophagy related 7 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319 		JBrowse link
G Atm ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24358288 PMID:24358288 RGD:10053570 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:29300489 PMID:23809007 RGD:13792656, RGD:13792681 NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:10,211,262...10,216,583 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:16423716 RGD:2300376 NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20079142 PMID:25450231 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 IMP
ISO 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20079142 PMID:17467744 RGD:1643494 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bdkrb1 bradykinin receptor B1 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973 		JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
G Becn1 beclin 1 treatment ISO
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20079142 PMID:20079142 RGD:11561913 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP RGD PMID:15081314 RGD:2293137 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G Brap BRCA1 associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198608 NCBI chr12:40,535,232...40,561,726
Ensembl chr12:40,535,232...40,561,726 		JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 susceptibility ISO DNA:SNPs:3' end: RGD PMID:18430236 RGD:14398488 NCBI chr13:60,964,127...61,397,044
Ensembl chr13:60,966,100...61,397,039 		JBrowse link
G C1qtnf6 C1q and TNF related 6 IEP protein:decreased expression:heart RGD PMID:25962701 RGD:529435444 NCBI chr 7:111,958,348...111,964,948
Ensembl chr 7:111,958,350...111,966,871 		JBrowse link
G C3 complement C3 treatment IEP mRNA, protein:increased expression:myocardium RGD PMID:16996480 PMID:31734577 RGD:1600605, RGD:408418726 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G C7 complement C7 IEP Protein:increased activity:serum, myocardium RGD PMID:15724448 RGD:1599522 NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672 		JBrowse link
G C8a complement C8 alpha chain IEP RGD PMID:7515561 RGD:1600501 NCBI chr 5:124,812,131...124,866,631
Ensembl chr 5:124,812,131...124,866,710 		JBrowse link
G C8b complement C8 beta chain IEP RGD PMID:7515561 RGD:1600501 NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516 		JBrowse link
G Cacybp calcyclin binding protein IEP mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta treatment IEP mRNA, protein:splice variants, increased expression:heart left ventricle (rat) RGD PMID:26067684 RGD:11097969 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276 		JBrowse link
G Casp1 caspase 1 severity
ameliorates 		ISO
IEP 		RGD PMID:17303764 PMID:33389498 RGD:2315913, RGD:242905187 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 ameliorates
treatment 		ISO
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:25450231 PMID:28622474 PMID:27904666 RGD:329333030, RGD:13782309 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:myocardium (rat) RGD PMID:22527939 RGD:7205672 NCBI chr11:77,738,398...77,813,639
Ensembl chr11:77,740,614...77,810,167 		JBrowse link
G Cat catalase IEP
ISO 		CTD Direct Evidence: therapeutic CTD
RGD		 PMID:21600015 PMID:14575298 RGD:1581148 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav3 caveolin 3 IEP Protein:increased expression:cytosol
mRNA, protein; increased expression; myocardium (rat) 		RGD PMID:12566108 PMID:29438664 RGD:1599542, RGD:126925221 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:147,137,797...147,153,967 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
IDA
ISO 		protein:increased expression:serum
DNA:snp:promoter:g.-2518A>G (human) 		RGD PMID:18459941 PMID:18753699 PMID:16116069 RGD:2307033, RGD:8549616, RGD:1581161 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:heart (rat) RGD PMID:18954648 RGD:4890013 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccn1 cellular communication network factor 1 ISO mRNA,protein:increased expression:myocardium (mouse) RGD PMID:15117851 RGD:329845570 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn2 cellular communication network factor 2 treatment IEP mRNA:increased expression:left ventricle (rat) RGD PMID:18167060 PMID:29849775 RGD:2314623, RGD:35673318 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccna2 cyclin A2 IEP protein:increased expression:cardiomyocyte: RGD PMID:23634243 RGD:10054471 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12719858 PMID:12853162 RGD:1581177, RGD:1581174 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 IDA RGD PMID:18954648 RGD:4890013 NCBI chr 8:132,463,533...132,511,601
Ensembl chr 8:132,463,788...132,511,593 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1 ClinVar PMID:24213632 NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973 		JBrowse link
G Cd14 CD14 molecule no_association ISO associated with Coronary Artery Disease;DNA:SNP:promoter RGD PMID:10195920 PMID:14587643 PMID:17436151 RGD:1580252, RGD:1580255, RGD:2314155 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd36 CD36 molecule severity IMP RGD PMID:22128087 RGD:6893560 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cd59b CD59b molecule IEP protein:decreased expression:myocardium RGD PMID:7515561 RGD:1600501 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B treatment IMP
ISO 		RGD PMID:22492676 PMID:22492676 RGD:10045366, RGD:10045366 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cfl1 cofilin 1 treatment IDA RGD PMID:24292258 RGD:11570534 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO associated with Myocardial Reperfusion Injury RGD PMID:23221371 RGD:11566046 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:18480670 RGD:4892633 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator susceptibility
no_association 		ISO DNA:polymorphism:promoter:-168A>G (human) RGD PMID:15821736 PMID:17183695 RGD:1358146, RGD:5491201 NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342 		JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:12359538 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478 		JBrowse link
G Ckm creatine kinase, M-type ISO CTD Direct Evidence: marker/mechanism CTD PMID:3279722 PMID:12359538 NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719 		JBrowse link
G Clu clusterin treatment ISO RGD PMID:20854280 RGD:9068409 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Col1a1 collagen type I alpha 1 chain treatment IEP RGD PMID:25636075 RGD:11041598 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col3a1 collagen type III alpha 1 chain treatment IEP RGD PMID:25636075 RGD:11041598 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain susceptibility ISO DNA:polymorphism: :p.Q1334H (human) RGD PMID:18077766 RGD:2311341 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain ISO DNA:SNP:CDS:E1386K (rs146092501) (human) RGD PMID:30226566 RGD:401851058 NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crp C-reactive protein IEP
ISO 		protein:increased expression:serum
associated with Angina, Unstable; 		RGD PMID:21046814 PMID:9761079 PMID:22446866 RGD:5131456, RGD:9491780, RGD:6482304 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Cs citrate synthase severity IDA
ISO 		protein:decreased expression:diaphragm, mitochondrion RGD PMID:1877670 PMID:34416105 RGD:243048469, RGD:243048471 NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938 		JBrowse link
G Csf2 colony stimulating factor 2 IMP RGD PMID:21326109 RGD:5131507 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:15639484 RGD:11039417 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 IEP RGD PMID:15090263 RGD:11565830 NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698 		JBrowse link
G Csnk2b casein kinase 2 beta IEP RGD PMID:15090263 RGD:11565830 NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO DNA:SNP:CDS:49A>G (human) RGD PMID:17652883 RGD:2301976 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:69,813,265...69,819,973 		JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:serum, heart (rat) RGD PMID:19958779 RGD:2315501 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP
IMP 		mRNA:increased expression:heart left ventricle RGD PMID:11820456 PMID:19187644 RGD:632503, RGD:2306567 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cyba cytochrome b-245 alpha chain IEP mRNA:increased expression:myocardium
mRNA:increase expression:ventricle myocardium: 		RGD PMID:18762777 PMID:11243862 RGD:2317860, RGD:1599690 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cybb cytochrome b-245 beta chain IEP mRNA:increase expression:ventricle myocardium RGD PMID:11243862 RGD:1599690 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IMP RGD PMID:18689429 RGD:2307303 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ameliorates IMP RGD PMID:33389498 RGD:242905187 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 susceptibility ISO DNA:polymorphism RGD PMID:17126841 RGD:1625380 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 ISO DNA:SNP:CDS:rs2060793, rs1993116, rs10766197 (human) RGD PMID:29804528 RGD:401901167 NCBI chr 1:178,166,984...178,232,191
Ensembl chr 1:178,219,704...178,232,423 		JBrowse link
G Dab2 DAB adaptor protein 2 IEP
IMP 		protein:increased expression:cardiomyocyte RGD PMID:21762377 PMID:20666606 RGD:7243156, RGD:7243158 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888 		JBrowse link
G Dab2ip DAB2 interacting protein onset ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:CDS:intron 1 (rs7025486) (human) 		CTD
RGD		 PMID:20622881 PMID:20622881 RGD:401901599 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:39,312,745...39,483,730 		JBrowse link
G Dag1 dystroglycan 1 treatment IDA RGD PMID:12034665 RGD:11541047 NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199 		JBrowse link
G Dcn decorin IEP RGD PMID:16311904 RGD:1598497 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dgkz diacylglycerol kinase zeta ISO CTD Direct Evidence: therapeutic CTD PMID:17071729 NCBI chr 3:98,359,804...98,401,847
Ensembl chr 3:98,359,804...98,401,951 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 IEP RGD PMID:15256074 RGD:1580899 NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:171,739,133...171,750,966 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A treatment IEP associated with heart failure; protein:increased expression, increased activity:heart left ventricle (rat) RGD PMID:26067684 RGD:11097969 NCBI chr11:47,360,824...47,479,033
Ensembl chr11:47,360,850...47,479,033 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:9607404 RGD:1580912 NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719 		JBrowse link
G Edn1 endothelin 1 severity ISO
IEP 		protein:increased secretion:plasma (human)
mRNA:increased expression:heart left ventricle (rat) 		RGD PMID:17893002 PMID:10573185 RGD:4144880, RGD:1580921 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Edn2 endothelin 2 IEP RGD PMID:10573185 RGD:1580921 NCBI chr 5:139,036,576...139,042,074
Ensembl chr 5:139,036,492...139,043,070 		JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:12524016 RGD:1580948 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Ednrb endothelin receptor type B IDA RGD PMID:12524016 RGD:1580948 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IEP RGD PMID:16765982 RGD:11252084 NCBI chr19:69,765,276...69,804,681 JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IEP RGD PMID:16765982 RGD:11252084 NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015 		JBrowse link
G Epas1 endothelial PAS domain protein 1 IEP RGD PMID:15247145 PMID:18484163 RGD:1580977, RGD:5147886 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729 		JBrowse link
G Ephb1 Eph receptor B1 ameliorates IEP RGD PMID:28622474 RGD:329333030 NCBI chr 8:111,386,432...111,823,759
Ensembl chr 8:111,386,432...111,823,759 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:19716829 RGD:5688358 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Epo erythropoietin treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19337937 PMID:21415704 RGD:10400907 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G Epor erythropoietin receptor IEP RGD PMID:21415704 RGD:10400907 NCBI chr 8:28,765,738...28,770,371
Ensembl chr 8:28,765,746...28,770,322 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 treatment IEP RGD PMID:26892146 RGD:11522702 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 treatment IEP RGD PMID:26892146 RGD:11522702 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Esr1 estrogen receptor 1 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD		 PMID:11894143 PMID:11919305 PMID:14600184 PMID:15133719 PMID:25741868 More... RGD:1331525 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G F10 coagulation factor X ISO ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to ClinVar PMID:10984565 PMID:12181036 PMID:25741868 NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280 		JBrowse link
G F12 coagulation factor XII susceptibility ISO DNA:polymorphism:promoter:-46C>T(human) RGD PMID:16411408 RGD:11041803 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664 		JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO ClinVar Annotator: match by term: Myocardial infarction, protection against | ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD
RGD		 PMID:8025280 PMID:9459313 PMID:9550516 PMID:10365735 PMID:10910914 More... RGD:1581022 NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948 		JBrowse link
G F2 coagulation factor II, thrombin susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism::20210G>A(human) 		CTD
RGD		 PMID:9292507 PMID:9531249 PMID:10027711 PMID:12480694 RGD:1581022 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G F3 coagulation factor III, tissue factor treatment IEP RGD PMID:21229253 RGD:11062083 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G F5 coagulation factor V no_association
susceptibility 		ISO CTD Direct Evidence: marker/mechanism
DNA:mutation:cds:1691G>A (human) 		CTD
RGD		 PMID:9531249 PMID:10590188 PMID:15131548 RGD:11564337, RGD:11564335 NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247 		JBrowse link
G F7 coagulation factor VII susceptibility ISO protein:increased activity:plasma (human)
ClinVar Annotator: match by term: F7-related condition | ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to | ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:missense mutation, repeat:cds, intron:p.R353Q, (human) 		OMIM
ClinVar
CTD
RGD		 PMID:627745 PMID:1634227 PMID:2070047 PMID:6812354 PMID:7919338 More... RGD:2312409, RGD:11049521, RGD:1580374 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738 		JBrowse link
G Fabp3 fatty acid binding protein 3 ISO RGD PMID:8326460 RGD:1582401 NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881 		JBrowse link
G Fga fibrinogen alpha chain treatment IEP RGD PMID:31734577 RGD:408418726 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fgb fibrinogen beta chain ISO GAD
RGD		 PMID:15118671 PMID:9437197 RGD:1331525, RGD:1580381 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgf1 fibroblast growth factor 1 treatment ISO RGD PMID:24200746 RGD:10449026 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:17439742 RGD:10402087 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ameliorates ISO RGD PMID:19358330 RGD:155663664 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Fgg fibrinogen gamma chain treatment IEP RGD PMID:31734577 RGD:408418726 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Fis1 fission, mitochondrial 1 IEP protein:increased expression:plantaris (rat) RGD PMID:24427319 RGD:11557988 NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP RGD PMID:16714360 RGD:1601493 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand treatment ISO RGD PMID:24184252 RGD:11049498 NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:104,749,983...104,757,038 		JBrowse link
G Fn1 fibronectin 1 IEP protein:decreased expression:heart RGD PMID:19695229 RGD:2325720 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:paraventricular nucleus hypothalamus, paraventricular nucleus thalamus RGD PMID:27601012 RGD:405649741 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase treatment ISO mRNA, protein:decreased expression:heart
DNA:SNP: :rs17817449 (human)
associated with type 2 diabetes mellitus;DNA:SNP:intron:rs9939609 (human) 		RGD PMID:29997116 PMID:26772723 PMID:20031593 PMID:29997116 RGD:329812009, RGD:11555187, RGD:329901766, RGD:329812009 NCBI chr19:31,456,749...31,865,011
Ensembl chr19:31,522,293...31,864,957 		JBrowse link
G Fzd2 frizzled class receptor 2 IEP mRNA:increased expression:heart left ventricle RGD PMID:9142123 RGD:4107058 NCBI chr10:88,061,988...88,063,898
Ensembl chr10:88,061,667...88,065,396 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:20462747 RGD:10449173 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gata4 GATA binding protein 4 treatment IMP
ISO 		CTD Direct Evidence: therapeutic CTD
RGD		 PMID:20200331 PMID:23948075 RGD:7327215 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gatm glycine amidinotransferase ISO RGD PMID:31972362 RGD:329961305 NCBI chr 3:130,112,508...130,137,664
Ensembl chr 3:130,112,509...130,129,355 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment IDA
IEP 		RGD PMID:32782412 PMID:26192027 RGD:329961570, RGD:329970290 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit susceptibility ISO DNA:snp:promoter:c.-129C>T (human)
ClinVar Annotator: match by term: GCLC-related condition | ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD
RGD		 PMID:12598062 PMID:25741868 PMID:28492532 PMID:12598062 RGD:1302515 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit susceptibility ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
CTD		 PMID:12081989 PMID:12975258 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19419996 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050 		JBrowse link
G Gh1 growth hormone 1 treatment ISO RGD PMID:12500159 RGD:11352745 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Ghrh growth hormone releasing hormone treatment IDA RGD PMID:24373935 RGD:10401242 NCBI chr 3:166,412,763...166,432,519
Ensembl chr 3:166,412,764...166,431,880 		JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP
IMP 		protein:decreased phosphorylation RGD PMID:22969867 PMID:29428663 PMID:22841862 RGD:7207261, RGD:13592597, RGD:7207262 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15982495 RGD:1580400 NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216 		JBrowse link
G Gja5 gap junction protein, alpha 5 treatment IEP RGD PMID:29428663 RGD:13592597 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:187,234,674...187,318,512 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:15269835 RGD:1580432 NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,829,832...55,854,560 		JBrowse link
G Gp6 glycoprotein VI sexual_dimorphism
treatment
no_association
susceptibility
onset 		ISO DNA:missense mutation:CDS:c.13254T>C (p.S219P) (human)
human protein in a mouse model
DNA:missense mutation:CDS:c.13254T>C (p.S219P) (rs1613662) (human)
DNA:missense mutation:exon 7:c.645213C>T (p.T249A) (human)
DNA:SNP, missense mutation:promoter, CDS:c.-148C>T, c.13254T>C (p.S219P) (human) 		RGD PMID:11571236 PMID:22814400 PMID:20723028 PMID:12417295 PMID:11571236 More... RGD:401793749, RGD:401824647, RGD:401794407, RGD:401793754, RGD:401793749, RGD:401793749 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:78,508,468...78,535,374 		JBrowse link
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:32026788 RGD:401793703 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO RGD PMID:14573732 RGD:1600662 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IMP
ISO 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16716347 PMID:16565311 RGD:10045368 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gsn gelsolin ameliorates ISO
IEP 		protein:decreased expression:blood serum (human) RGD PMID:9142022 PMID:28622474 RGD:329333022, RGD:329333030 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:25119867 RGD:10401898 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1 ClinVar PMID:24213632 NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates IMP RGD PMID:33389498 RGD:242905187 NCBI chr 1:207,160,175...207,162,851 JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEP RGD PMID:11481570 RGD:2302229 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA:increased expression:heart RGD PMID:19615879 RGD:11041636 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297 		JBrowse link
G Hfe homeostatic iron regulator no_association
susceptibility 		ISO RGD PMID:12850485 PMID:10491370 RGD:1582672, RGD:1582697 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208 		JBrowse link
G Hgf hepatocyte growth factor treatment ISO protein:increased expression:serum: RGD PMID:12419930 PMID:16570015 RGD:8548609, RGD:8548632 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ameliorates
treatment 		IEP
ISO 		mRNA:increased expression:heart left ventricle
human gene in a rat model 		RGD PMID:18484163 PMID:28622474 PMID:15247145 PMID:15999059 RGD:5147886, RGD:329333030, RGD:1580977, RGD:9068466 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IDA
ISO 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21113057 PMID:23188125 RGD:10402174 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmox1 heme oxygenase 1 IEP
IDA 		RGD PMID:12392996 PMID:20925964 RGD:1598393, RGD:4145134 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hp haptoglobin susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16597321 PMID:17068284 PMID:17207726 PMID:3990081 PMID:2613263 RGD:1626360, RGD:1626354 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ameliorates ISO RGD PMID:28522730 PMID:26465199 RGD:329902054, RGD:11087531 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IEP
ISO 		mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:17587755 PMID:17587755 RGD:2308939 NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:17202668 RGD:1624230 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP
ISO 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10070497 PMID:23139358 RGD:8547733 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Igf1 insulin-like growth factor 1 severity IEP
ISO 		mRNA, protein:increased expression:myocardium RGD PMID:19295919 PMID:16635594 RGD:2306696, RGD:1598421 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA,protein:increased expression:myocyte: RGD PMID:8682060 RGD:10046050 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Il10 interleukin 10 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15883752 PMID:16310260 PMID:15466015 RGD:1598480 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il17a interleukin 17A IEP mRNA, protein:increased expression:heart left ventricle (rat) RGD PMID:23096364 RGD:9095344 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il18 interleukin 18 ameliorates IEP RGD PMID:33389498 RGD:242905187 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il18bp interleukin 18 binding protein ISO RGD PMID:19805173 RGD:4889400 NCBI chr 1:165,784,916...165,787,990
Ensembl chr 1:165,784,069...165,786,955 		JBrowse link
G Il1b interleukin 1 beta ameliorates IDA
IEP
ISO 		CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat) 		CTD
RGD		 PMID:11743230 PMID:15883752 PMID:16310260 PMID:23143013 PMID:33389498 More... RGD:7175553, RGD:242905187, RGD:7204425 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:18474815 PMID:19005744 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il4r interleukin 4 receptor IEP mRNA:increased expression:heart RGD PMID:10807530 RGD:4889985 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636 		JBrowse link
G Il6 interleukin 6 treatment ISO
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15883752 PMID:16310260 PMID:31734577 RGD:408418726 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor IEP RGD PMID:12123772 RGD:1625444 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Inhba inhibin subunit beta A IEP
ISO 		mRNA:increased expression:heart (rat)
mRNA:increased expression:myocardium (mouse) 		RGD PMID:14993131 PMID:32427381 RGD:1580888, RGD:329849118 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508 		JBrowse link
G Inhbb inhibin subunit beta B ISO mRNA:increased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609 		JBrowse link
G Isl1 ISL LIM homeobox 1 ameliorates ISO RGD PMID:29482621 PMID:22727192 RGD:243048463, RGD:243048464 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442 		JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility
no_association 		ISO RGD PMID:16697311 PMID:10194421 PMID:15227729 RGD:1582296, RGD:1581029, RGD:1582294 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509 		JBrowse link
G Itga3 integrin subunit alpha 3 IEP protein:increased expression:myocardium (rat) RGD PMID:19041328 RGD:2325287 NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901 		JBrowse link
G Itgam integrin subunit alpha M treatment ISO RGD PMID:29933226 RGD:329853753 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Itgb1 integrin subunit beta 1 treatment IMP RGD PMID:28367125 RGD:13602094 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Itgb3 integrin subunit beta 3 no_association
susceptibility 		ISO
IEP 		DNA:polymorphism:exon:
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
mRNA, protein:increased expression:myocardium
CTD Direct Evidence: marker/mechanism
associated with arteriosclerosis; DNA:polymorphism:exon 		OMIM
ClinVar
CTD
RGD		 PMID:1371279 PMID:2014236 PMID:7570918 PMID:8598867 PMID:8667943 More... RGD:5128498, RGD:633129, RGD:5128481, RGD:5128476 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160 		JBrowse link
G Jak2 Janus kinase 2 susceptibility IMP associated with Myocardial Reperfusion Injury RGD PMID:22749532 RGD:10403083 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 treatment IDA RGD PMID:23647964 RGD:7247426 NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,565,600...96,570,901 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP mRNA:decreased expression:heart left ventricle, epicardium, endocardium (rat) RGD PMID:21683547 RGD:9831182 NCBI chr13:103,297,387...103,494,686
Ensembl chr13:103,297,393...103,494,686 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 susceptibility ISO DNA:SNPs,haplotypes:introns:multiple RGD PMID:19644414 RGD:329969896 NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:89,086,814...89,102,275 		JBrowse link
G Kdm5b lysine demethylase 5B ameliorates ISO RGD PMID:36481938 RGD:329901769 NCBI chr13:48,554,367...48,625,721
Ensembl chr13:48,554,420...48,626,423 		JBrowse link
G Kdm6a lysine demethylase 6A IEP mRNA:increased expression:myocardium (rat) RGD PMID:30887465 RGD:151665136 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:6,920,343...7,059,960 		JBrowse link
G Kdr kinase insert domain receptor treatment ISO
IDA 		RGD PMID:16698275 PMID:25936512 RGD:1581717, RGD:126925214 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Kif6 kinesin family member 6 no_association
treatment 		ISO DNA:SNP: :rs20455 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :p.W719R (rs20455) (human) 		CTD
RGD		 PMID:21943003 PMID:18222354 PMID:20927332 PMID:26997531 PMID:19371834 More... RGD:243048446, RGD:243048450, RGD:243048449, RGD:243048447, RGD:11097528 NCBI chr 9:18,573,925...18,870,789
Ensembl chr 9:18,573,789...18,870,729 		JBrowse link
G Klf13 KLF transcription factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr 1:126,917,671...126,948,436
Ensembl chr 1:126,916,781...126,961,056 		JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12411458 NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270 		JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 ISO RGD PMID:17022964 RGD:1641799 NCBI chr 1:103,514,639...103,518,676
Ensembl chr 1:103,514,590...103,518,712 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:121,922,187...122,087,675 		JBrowse link
G Lcat lecithin cholesterol acyltransferase IDA RGD PMID:16640830 RGD:1581773 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081 		JBrowse link
G Lcn2 lipocalin 2 ameliorates ISO RGD PMID:27800610 RGD:126790572 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:3279722 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Ldlr low density lipoprotein receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lefty1 left right determination factor 1 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr13:95,188,091...95,191,488
Ensembl chr13:95,188,091...95,191,488 		JBrowse link
G Lgals2 galectin 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to 		OMIM
CTD
ClinVar
RGD		 PMID:15129282 PMID:15129282 RGD:1581852 NCBI chr 7:112,283,630...112,290,228
Ensembl chr 7:112,282,822...112,285,392 		JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Lipg lipase G, endothelial type susceptibility ISO DNA:polymorphism: :584C>T RGD PMID:17526978 RGD:1641818 NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260 		JBrowse link
G Lox lysyl oxidase ISO RGD PMID:14553832 RGD:1581883 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Lpl lipoprotein lipase susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP: :p.D9N (rs1801177) (human) RGD PMID:18823627 RGD:2313302 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO RGD PMID:12402342 RGD:1581913 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196 		JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
susceptibility
onset 		ISO DNA:missense mutation:cds:p.R952Q (human)
ClinVar Annotator: match by term: LRP8-related condition | ClinVar Annotator: match by term: Myocardial infarction, susceptibility to | ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM
RGD		 PMID:17847002 PMID:25741868 PMID:28492532 PMID:18592168 PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:127,792,299...127,864,207 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 susceptibility ISO RGD PMID:12394648 RGD:1581922 NCBI chr14:79,876,002...79,888,011
Ensembl chr14:79,875,708...79,890,034 		JBrowse link
G Lta lymphotoxin alpha no_association
susceptibility
severity 		ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:804C>A (p.T26N) (human) 		ClinVar
OMIM
CTD
RGD		 PMID:12426569 PMID:12746914 PMID:14681301 PMID:15129282 PMID:15266304 More... RGD:1581940, RGD:8548841, RGD:1580417 NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP RGD PMID:20079142 RGD:11561913 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:22635076 RGD:10412335 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 treatment IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:16183734 PMID:27121011 RGD:2298758, RGD:11073666 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:15653762 RGD:1582282 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ameliorates IEP RGD PMID:28622474 RGD:329333030 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:9753871 RGD:1582468 NCBI chr12:26,530,886...26,543,841
Ensembl chr12:26,530,881...26,543,841 		JBrowse link
G Mdk midkine IEP RGD PMID:9568069 RGD:1582488 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743 		JBrowse link
G Mef2a myocyte enhancer factor 2a ISO RGD PMID:15811259 RGD:1580548 NCBI chr 1:130,258,083...130,392,819
Ensembl chr 1:130,260,339...130,392,162 		JBrowse link
G Mef2c myocyte enhancer factor 2C treatment IMP RGD PMID:23948075 RGD:7327215 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640 		JBrowse link
G Meox2 mesenchyme homeobox 2 IEP protein:decreased expression:heart (rat) RGD PMID:24155330 RGD:155882536 NCBI chr 6:59,584,025...59,644,722
Ensembl chr 6:59,583,785...59,644,700 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 treatment ISO human gene and cell line in a rat model RGD PMID:32550911 RGD:242905196 NCBI chr 1:143,147,671...143,149,189
Ensembl chr 1:143,147,671...143,149,189 		JBrowse link
G Mff mitochondrial fission factor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23867156 PMID:23867156 RGD:12879458 NCBI chr 9:91,455,931...91,484,171
Ensembl chr 9:91,455,871...91,484,171 		JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:20886221 RGD:12738232 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495 		JBrowse link
G Mgp matrix Gla protein susceptibility ISO RGD PMID:11073842 RGD:1582503 NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198609 NCBI chr13:97,502,040...97,547,155
Ensembl chr13:97,494,275...97,543,587 		JBrowse link
G Miat myocardial infarction associated transcript susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM		 PMID:17066261 NCBI chr12:50,075,026...50,090,259 JBrowse link
G Mif macrophage migration inhibitory factor ISO
IEP 		protein:increased expression:plasma
mRNA, protein:increased expression:myocardium 		RGD PMID:11589847 PMID:12704210 RGD:1642008, RGD:1642003 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mir125b2 microRNA 125b-2 ISO CTD Direct Evidence: therapeutic CTD PMID:29122578 NCBI chr11:29,732,572...29,732,659 JBrowse link
G Mir143 microRNA 143 ISO
IEP 		RNA:increased expression:myocardium:
RNA:increased expression:plasma, left ventricle: 		RGD PMID:28887629 PMID:29728596 RGD:155882580, RGD:155882581 NCBI chr18:57,371,349...57,371,453 JBrowse link
G Mir145 microRNA 145 treatment
ameliorates 		ISO
IMP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:29956747 PMID:30146700 PMID:32890431 RGD:155260296, RGD:155260294 NCBI chr18:57,369,983...57,370,070 JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:31207208 RGD:21066347 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mir208a microRNA 208a treatment ISO
IEP 		miRNA:increased expression:heart RGD PMID:26688617 PMID:26861724 RGD:11536862, RGD:242905213 NCBI chr15:32,395,552...32,395,634 JBrowse link
G Mir223 microRNA 223 IEP RNA:increased expression:heart RGD PMID:29608885 RGD:21408565 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:65,151,383...65,151,492 		JBrowse link
G Mir25 microRNA 25 ISO RNA:increased expression:myocardium: RGD PMID:28887629 RGD:155882580 NCBI chr12:22,156,641...22,156,724 JBrowse link
G Mir30a microRNA 30a treatment IDA RGD PMID:29849775 RGD:35673318 NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011 		JBrowse link
G Mir30c1 microRNA 30c-1 ISO CTD Direct Evidence: therapeutic CTD PMID:34217758 NCBI chr 5:139,634,455...139,634,543 JBrowse link
G Mir30e microRNA 30e IEP miRNA:decreased expression:heart (rat) RGD PMID:25950484 RGD:11541106 NCBI chr 5:139,637,450...139,637,541
Ensembl chr 5:139,637,450...139,637,541 		JBrowse link
G Mir320a microRNA 320a treatment ISO RGD PMID:19380620 RGD:155882541 NCBI chr15:51,926,088...51,926,169
Ensembl chr15:51,926,088...51,926,169 		JBrowse link
G Mir423 microRNA 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24253456 NCBI chr10:62,412,272...62,412,350 JBrowse link
G Mir761 microRNA 761 ISO CTD Direct Evidence: therapeutic CTD PMID:23867156 NCBI chr 5:129,005,205...129,005,280
Ensembl chr 5:129,005,205...129,005,280 		JBrowse link
G Mlxipl MLX interacting protein-like susceptibility ISO DNA:SNP:cd: C771G, p.Q241H (rs3812316) (human) RGD PMID:24448738 RGD:401799621 NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660 		JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO
IEP
IDA 		protein:increased expression, increased activity:heart left ventricle (rat)
human gene in rat model
associated with Coronary Artery Disease; DNA:snps, haplotype:promoter:g.-519A>G, g.-340T>C (human) 		RGD PMID:15009768 PMID:8531210 PMID:11179039 PMID:19797822 PMID:16210545 RGD:1582535, RGD:7207198, RGD:7207136, RGD:7207135, RGD:1582520 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:15782494 RGD:1582556 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105 		JBrowse link
G Mmp14 matrix metallopeptidase 14 IEP
ISO 		RGD PMID:10773235 PMID:16461815 RGD:1582587, RGD:1582569 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP
ISO
IDA 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16310260 PMID:24358288 PMID:10773235 PMID:11179039 RGD:1582587, RGD:7207136 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:15467919 RGD:1580551 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO RGD PMID:16769909 RGD:1582373 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755 		JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility ISO
IEP
IDA 		protein:increased expression:coronary artery, plasma (human)
protein:increased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:heart left ventricle (rat)
DNA:snps:promoter, exon:g.-1562C>T, p.R279Q (rs3918242, rs2664538) (human) 		CTD
RGD		 PMID:16310260 PMID:24358288 PMID:15118287 PMID:25520329 PMID:8531210 More... RGD:1582645, RGD:13204799, RGD:7207198, RGD:7207049, RGD:1582639, RGD:1582653 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mstn myostatin ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:55,944,513...55,950,913 		JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 ISO DNA:missense mutation: :m.5178C>A (p.L237M) (human) RGD PMID:15262184 RGD:1581054 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,892...4,929 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO associated with Kidney Failure, Chronic; DNA:transition:cds:g.677C>T rs1801133 (human)
DNA:SNP: :677C>T (human) 		RGD PMID:19272686 PMID:10090925 RGD:6893548, RGD:10449412 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IDA protein:decreased serine phosphorylation:heart
associated with Diabetes Mellitus, Experimental 		RGD PMID:20352476 PMID:23773982 RGD:10041035, RGD:10041040 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Myh6 myosin heavy chain 6 IEP RGD PMID:15090263 RGD:11565830 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333 		JBrowse link
G Myh7 myosin heavy chain 7 ISO
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11743230 PMID:15090263 RGD:11565830 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO
IEP 		mRNA, protein:increased expression:heart
protein:alternative form, increased expression:myocardium 		RGD PMID:19853610 PMID:23462508 RGD:2325979, RGD:40924663 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971 		JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr 2:117,447,605...117,461,943
Ensembl chr 2:117,447,035...117,461,590 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IDA
ISO 		RGD PMID:23290949 PMID:24915518 RGD:10412734, RGD:10412738 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:19616538 RGD:10413879 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Ngf nerve growth factor treatment ISO protein:increased expression:myocardium RGD PMID:20360245 PMID:20360245 RGD:405100231, RGD:405100231 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nlk nemo like kinase IEP mRNA, protein:decreased expression:heart RGD PMID:26861724 RGD:242905213 NCBI chr10:63,965,432...64,089,006 JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ameliorates IEP RGD PMID:33389498 RGD:242905187 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nono non-POU domain containing, octamer-binding ameliorates ISO RGD PMID:35247074 RGD:155882458 NCBI chr  X:70,594,116...70,611,976
Ensembl chr  X:70,593,888...70,611,979 		JBrowse link
G Nos2 nitric oxide synthase 2 treatment ISO
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10090345 PMID:11489778 PMID:26192027 RGD:329970290 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility
treatment 		ISO
IEP
IDA 		DNA:repeats:intron
protein:decreased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism
human gene in rat model
DNA:duplication:intron:IVS4?-?+27 (human) 		CTD
RGD		 PMID:10510054 PMID:16337503 PMID:10531147 PMID:29311930 PMID:28980197 More... RGD:5128481, RGD:13503346, RGD:13450930, RGD:7771563, RGD:7771561, RGD:1580284, RGD:1580283 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Npm1 nucleophosmin 1 ISO protein:increased expression:cardiomyocyte: RGD PMID:21444791 RGD:11535018 NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr  X:18,245,740...18,256,024 		JBrowse link
G Nppa natriuretic peptide A ISO
IEP 		DNA:snp:cds:c.2238T>C (human)
CTD Direct Evidence: marker/mechanism|therapeutic 		CTD
RGD		 PMID:9527094 PMID:11743230 PMID:12514664 PMID:16087130 RGD:1579982, RGD:1580000 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B IMP
ISO
IEP 		RGD PMID:19858735 PMID:17639095 PMID:17256064 RGD:2324680, RGD:7247724, RGD:1642266 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Npr1 natriuretic peptide receptor 1 susceptibility ISO DNA:missense mutation:cds:p.M341I (human) RGD PMID:14646971 RGD:1580174 NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:178,231,766...178,247,088 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 susceptibility ISO DNA:SNPs, haplotype:promoter:c.-115G>A, c.-840C>A (rs12221497, rs61896015) (human) RGD PMID:21903943 RGD:401842365 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16413583 PMID:17587755 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078 		JBrowse link
G Nrg1 neuregulin 1 treatment ISO
IEP 		RGD PMID:24200746 PMID:26892146 PMID:27993643 RGD:10449026, RGD:11522702, RGD:405145704 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 susceptibility ISO DNA:missense mutation:cds:p.K167N (human)
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to | ClinVar Annotator: match by term: OLR1-related condition
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
CTD
RGD		 PMID:12646194 PMID:12810610 PMID:14684693 PMID:12646194 RGD:1580996 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment IEP RGD PMID:20886221 RGD:12738232 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
G Oprd1 opioid receptor, delta 1 IDA
IMP 		RGD PMID:12798419 PMID:15076225 RGD:2316587, RGD:9831425 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:149,590,244...149,624,999 		JBrowse link
G Oprk1 opioid receptor, kappa 1 IMP RGD PMID:15076225 RGD:9831425 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:18,657,871...18,675,671 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19334620 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:145,629,967...145,633,410 		JBrowse link
G Pappa pappalysin susceptibility ISO DNA:polymorphism:intron
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:11586954 PMID:17700210 RGD:1642324 NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO protein:altered processing:left ventricle (mouse) RGD PMID:21282286 RGD:5684012 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 ISO DNA:SNP:intron: (rs6080699) (human) RGD PMID:20036365 RGD:6483554 NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:151,333,234...151,638,849 		JBrowse link
G Pde3a phosphodiesterase 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:175,904,077...176,169,270 		JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:17339532 RGD:2314468 NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298 		JBrowse link
G Pdgfd platelet derived growth factor D IEP mRNA,protein:altered expression:myocardium: RGD PMID:21767547 RGD:9854703 NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:11,773,475...12,007,271 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 IEP protein:decreased expression:right heart ventricle, ventricular septum RGD PMID:17089028 RGD:2302667 NCBI chr12:44,946,307...44,967,890
Ensembl chr12:44,963,675...44,971,780 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 onset
no_association 		ISO DNA:polymorphisms: :p.N563S, p.G670R (human)
DNA:missense mutation:cds:p.R643G (human)
DNA:missense mutations:cds:p.L125V, p.S563N (human) 		RGD PMID:11795274 PMID:15488875 PMID:15265022 RGD:2311656, RGD:6771224, RGD:1581009 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Pgf placental growth factor ISO
IMP 		RGD PMID:20649603 PMID:21329947 PMID:22114497 RGD:6483584, RGD:6483777, RGD:6483773 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 susceptibility
severity
no_association 		ISO
IEP 		CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs9369640) (human)
DNA:SNPs:multiple (human)
DNA:SNP:intron:(rs12526453) (human)
mRNA:increased expression:peripheral blood mononuclear cells (human)
DNA:SNPs:intron 3: (rs9349379, rs2026458, rs2876300) (human)
DNA:SNP:intron:g.13035530G>C (rs12526453) (human)
mRNA, protein:decreased expression:heart left ventricle (rat) 		CTD
RGD		 PMID:19198609 PMID:26098115 PMID:25738804 PMID:25838425 PMID:26086777 More... RGD:11052994, RGD:11052493, RGD:11056926, RGD:401900171, RGD:401900171, RGD:401851907, RGD:11053274 NCBI chr17:21,769,006...22,246,227
Ensembl chr17:21,768,662...22,244,586 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34351043 NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:20056919 RGD:6482688 NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509 		JBrowse link
G Pla2g7 phospholipase A2 group VII ISO protein:decreased expression:serum RGD PMID:19644070 RGD:6482786 NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747 		JBrowse link
G Plat plasminogen activator, tissue type treatment ISO DNA:snp:enhancer:g.-7351C>T (human)
CTD Direct Evidence: therapeutic 		CTD
RGD		 PMID:1430592 PMID:1492007 PMID:1898952 PMID:1899364 PMID:1900011 More... RGD:1580881, RGD:11541077 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
G Plau plasminogen activator, urokinase ISO
IEP 		DNA:SNP:3' utr:c.*141C>T (rs4065) (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:increased expression:myocardium 		CTD
RGD		 PMID:1908371 PMID:2174952 PMID:2382605 PMID:3068399 PMID:3984876 More... RGD:6484126, RGD:6484145, RGD:6484133 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO
IEP 		mRNA, protein:increased expression:myocardium RGD PMID:12393744 PMID:20952728 RGD:1580897, RGD:6484133 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130 		JBrowse link
G Plcb1 phospholipase C beta 1 IEP protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646 		JBrowse link
G Plcb3 phospholipase C beta 3 IEP protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr 1:213,572,499...213,589,585
Ensembl chr 1:213,574,166...213,589,583 		JBrowse link
G Pln phospholamban treatment IDA
IEP
ISO 		protein:decreased expression:heart left ventricle (rat)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:16026515 PMID:16162791 PMID:23781262 PMID:26067684 RGD:7327176, RGD:11097969 NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241 		JBrowse link
G Pon1 paraoxonase 1 ISO RGD PMID:10978258 PMID:10610741 RGD:1580202, RGD:1580198 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Postn periostin IEP protein:increased expression:heart: RGD PMID:24212842 RGD:10041024 NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO DNA:SNP:intron:rs4253623, minor allele associated with increased risk (human) RGD PMID:18549840 RGD:5562819 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP
ISO 		protein:decreased expression:heart (rat)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:22503866 PMID:22503866 PMID:22087236 RGD:7242181, RGD:6484266 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: therapeutic
RNA:decreased expression:myocardium: 		CTD
RGD		 PMID:16782078 PMID:28887629 RGD:155882580 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Prkd1 protein kinase D1 treatment IEP RGD PMID:26064267 RGD:289474908 NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO RGD PMID:10936861 RGD:11100014 NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964 		JBrowse link
G Psma6 proteasome 20S subunit alpha 6 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PSMA6-related condition 		CTD
ClinVar
OMIM		 PMID:16845397 PMID:19282875 NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717 		JBrowse link
G Ptgis prostaglandin I2 synthase susceptibility ISO DNA:SNP::1117C>A (human)
DNA:silent mutation:exon 8:1117C>A (human)
DNA:SNP:CDS: (rs5629) (human) 		RGD PMID:19040046 PMID:12040339 PMID:19327107 PMID:19046748 RGD:401901147, RGD:401901268, RGD:401901155, RGD:2313891 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:15138244 RGD:1581289 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptn pleiotrophin IEP protein:increased expression:myocardium (rat) RGD PMID:17925408 RGD:10044023 NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482 		JBrowse link
G Rad50 RAD50 double strand break repair protein treatment IDA RGD PMID:15623426 RGD:9831390 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Ranbp1 RAN binding protein 1 IEP protein:decreased expression:heart ventricle, cytoplasm (rat) RGD PMID:25341891 RGD:9835001 NCBI chr11:96,246,912...96,255,145
Ensembl chr11:96,246,740...96,255,145 		JBrowse link
G Rbp4 retinol binding protein 4 ISO protein:increased expression:blood serum (human) RGD PMID:25142320 RGD:329845867 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898 		JBrowse link
G Reg1a regenerating family member 1 alpha IEP mRNA:increased expression:heart left ventricle (rat) RGD PMID:15778284 RGD:9850130 NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585 		JBrowse link
G Ren renin susceptibility ISO associated with Hypertension; protein:increased activity:plasma (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:1668233 PMID:1759997 RGD:6892687 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Retn resistin ISO protein:increased expression:plasma RGD PMID:18997620 RGD:7207152 NCBI chr12:6,508,653...6,511,115
Ensembl chr12:6,508,801...6,511,116 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP protein:increased threonine phosphorylation:heart left ventricle RGD PMID:16540832 RGD:1642998 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Ryr1 ryanodine receptor 1 IDA protein:hyperphosphorylation:extensor digitorum longus: RGD PMID:12824280 RGD:329813076 NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305 		JBrowse link
G S100b S100 calcium binding protein B IEP
ISO 		mRNA, protein:increased expression:left ventricle myocardium, plasma
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:9788975 PMID:19910580 RGD:2325647 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081 		JBrowse link
G Sdc1 syndecan 1 IEP mRNA:increased expression:myocardium RGD PMID:9237025 RGD:2311712 NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500 		JBrowse link
G Sdc4 syndecan 4 ISO protein:increased expression:plasma RGD PMID:11372670 RGD:2312328 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670 		JBrowse link
G Sell selectin L ISO CTD Direct Evidence: marker/mechanism CTD PMID:10070497 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600 		JBrowse link
G Selp selectin P susceptibility ISO
IEP 		associated with Hypertension;protein:increased expression:plasma
protein:increased expression:serum
DNA:polymorphisms, haplotypes:cds:p.S290N, p.N562D, p.T715P (human) 		RGD PMID:17391113 PMID:21162967 PMID:21567088 PMID:12165563 RGD:2312304, RGD:6219003, RGD:6218991, RGD:1580075 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987 		JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO
IMP 		DNA:deletion:promoter:g.-676_-674delG (human) RGD PMID:12477941 PMID:16053971 RGD:1626626, RGD:8547882 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 IEP
ISO 		RGD PMID:19109969 PMID:19079247 RGD:4107088, RGD:155883169 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:40,392,633...40,414,335 		JBrowse link
G Shh sonic hedgehog signaling molecule treatment IMP RGD PMID:20052412 RGD:12879408 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901 		JBrowse link
G Sirt1 sirtuin 1 IEP protein:altered localization:nucleus RGD PMID:20089851 RGD:2316169 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Sirt3 sirtuin 3 treatment IEP RGD PMID:24471974 RGD:9586050 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 IEP protein:decreased expression:infarcted heart RGD PMID:17034771 RGD:1642800 NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,313,015...18,330,045 		JBrowse link
G Slc27a6 solute carrier family 27 member 6 IEP protein:decreased expression:heart RGD PMID:17034771 RGD:1642800 NCBI chr18:54,238,697...54,297,595
Ensembl chr18:54,238,729...54,312,632 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor treatment IEP RGD PMID:23361363 RGD:9999400 NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822 		JBrowse link
G Smad2 SMAD family member 2 treatment
ameliorates 		IEP
ISO 		RGD PMID:11087260 PMID:33409963 RGD:12903276, RGD:401794430 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388 		JBrowse link
G Smad3 SMAD family member 3 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324 		JBrowse link
G Smad4 SMAD family member 4 treatment IEP RGD PMID:11087260 RGD:12903276 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEP protein:increased expression:heart RGD PMID:16377761 RGD:2298918 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO CTD Direct Evidence: therapeutic
human gene in a rat model 		CTD
RGD		 PMID:21600015 PMID:11864929 PMID:22006090 RGD:1581222, RGD:8655953 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 IDA
ISO
IEP 		CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12160945 PMID:14575298 PMID:9250167 RGD:1581148, RGD:1580839 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP mRNA:increased expression:heart RGD PMID:12826287 RGD:2300056 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:12939547 PMID:14500723 RGD:1581386, RGD:1581325 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 treatment IDA protein:increased phosphorylation:heart left ventricle(rat) RGD PMID:26067684 RGD:11097969 NCBI chr10:73,335,519...73,342,549
Ensembl chr10:73,336,422...73,342,548 		JBrowse link
G Tbx3 T-box transcription factor 3 IEP RGD PMID:19341743 RGD:5132891 NCBI chr12:42,540,378...42,555,490
Ensembl chr12:42,540,378...42,554,171 		JBrowse link
G Tbx5 T-box transcription factor 5 treatment IMP RGD PMID:23948075 RGD:7327215 NCBI chr12:42,342,926...42,399,723
Ensembl chr12:42,348,485...42,395,359 		JBrowse link
G Tek TEK receptor tyrosine kinase IEP protein:increased expression:ventricle myocardium RGD PMID:16714360 RGD:1601493 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991 		JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO
IEP 		mRNA,protein:increased expression:heart: RGD PMID:15630488 PMID:21229253 PMID:14656922 RGD:11060131, RGD:11062083, RGD:11060139 NCBI chr 3:89,939,862...89,989,253
Ensembl chr 3:89,939,868...89,980,742 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 susceptibility ISO
IEP 		associated with Coronary Disease;DNA:polymorphism:promoter:-509C>T (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:heart: 		CTD
RGD		 PMID:16310260 PMID:16543493 PMID:27121011 PMID:15118671 RGD:1601560, RGD:11073666, RGD:1331525 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP RGD PMID:14575314 RGD:2302107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IEP RGD PMID:10198196 RGD:1601617 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEP protein:increased expression:myocardium RGD PMID:10198196 RGD:1601617 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Th tyrosine hydroxylase no_association ISO DNA:polymorphism:intron:g.1170_1173dupTCAT (human) RGD PMID:16139102 RGD:1580048 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9843165 PMID:10627464 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582 		JBrowse link
G Thbs1 thrombospondin 1 IEP mRNA, protein:increased expression:myocardium RGD PMID:16179730 RGD:2317960 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214 		JBrowse link
G Tlr4 toll-like receptor 4 ISO DNA:SNP:intron:rs1927911, minor allele associated with decreased risk (human) RGD PMID:15864121 PMID:18549840 RGD:1580734, RGD:5562819 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tm6sf2 transmembrane 6 superfamily member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24633158 NCBI chr16:19,378,148...19,385,360
Ensembl chr16:19,378,152...19,385,467 		JBrowse link
G Tnc tenascin C IEP protein:increased expression:heart, fibroblast RGD PMID:11454990 RGD:4889618 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnf tumor necrosis factor IEP
ISO 		mRNA, protein:increased expression:left ventricle myocardium, plasma
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:15883752 PMID:16310260 PMID:21362018 RGD:5130892 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO RGD PMID:15926884 RGD:1620893 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20082609 NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 IEP protein:increased expression:heart, cardiomyocyte, endothelial cell (rat) RGD PMID:18353719 RGD:2317281 NCBI chr 5:170,768,413...170,776,749
Ensembl chr 5:170,768,416...170,776,046 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP
IMP
IDA 		mRNA, protein:increased expression:left ventricle myocardium (rat) RGD PMID:21362018 PMID:20651834 PMID:15117889 RGD:5130892, RGD:5130975, RGD:1624194 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IEP mRNA, protein:decreased expression:left ventricle myocardium (rat) RGD PMID:21362018 RGD:5130892 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Tnfsf11 TNF superfamily member 11 ISO protein:increased expression:serum RGD PMID:18298349 RGD:2302363 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnfsf4 TNF superfamily member 4 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD		 PMID:15750594 RGD:1580396 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Tnni3 troponin I3, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12359538 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Tnnt2 troponin T2, cardiac type ISO RGD PMID:15226628 RGD:1580441 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates
disease_progression 		ISO
IMP 		RGD PMID:25840803 PMID:25840803 PMID:25840803 RGD:127284842, RGD:127284842, RGD:127284842 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:20,261,408...20,276,892 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:27671317 RGD:13792689 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Trpv1em1Sage transient receptor potential cation channel, subfamily V, member 1; ZFN induced mutant 1, Sage IMP RGD PMID:27671317 RGD:13792689
G Ttn titin IEP RGD PMID:12221049 RGD:1580780 NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171 		JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:14677813 RGD:1580785 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP mRNA:decreased expression:heart left ventricle (rat) RGD PMID:18515646 RGD:5134341 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Ubd ubiquitin D IEP
IMP 		mRNA, protein; increased expression; myocardium (rat)
associated with induced myocardial infarction 		RGD PMID:29438664 PMID:29438664 RGD:126925221, RGD:126925221 NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,390,600...1,413,965 		JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221
G Uts2 urotensin 2 IEP associated with Heart Failure, Congestive;mRNA:increased expression:heart ventricle RGD PMID:15549273 RGD:2306846 NCBI chr 5:166,725,471...166,739,063
Ensembl chr 5:166,733,671...166,739,059 		JBrowse link
G Uts2r urotensin 2 receptor IEP associated with Heart Failure, Congestive;mRNA:increased expression:heart ventricle RGD PMID:15549273 RGD:2306846 NCBI chr10:106,936,398...106,937,558
Ensembl chr10:106,932,325...106,938,056 		JBrowse link
G Vcan versican IEP RGD PMID:16311904 RGD:1598497 NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:22,497,035...22,595,955 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25488258 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 treatment IDA RGD PMID:20601275 RGD:10003049 NCBI chr15:2,512,214...2,526,105
Ensembl chr15:2,512,216...2,532,229 		JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO
IDA 		protein:increased expression:serum,platelet: RGD PMID:10652191 PMID:25936512 RGD:7483604, RGD:126925214 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vegfb vascular endothelial growth factor B ISO RGD PMID:17975666 RGD:2314324 NCBI chr 1:213,601,570...213,607,254
Ensembl chr 1:213,600,966...213,607,152 		JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:heart: RGD PMID:19435557 RGD:11080745 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
G Wdr12 WD repeat domain 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198609 PMID:25915632 NCBI chr 9:68,969,547...68,996,811
Ensembl chr 9:68,969,547...68,996,811 		JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:9021029 RGD:1580821 NCBI chr16:65,466,552...65,602,951
Ensembl chr16:65,456,254...65,602,951 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 susceptibility ISO DNA:polymorphism:: (human) RGD PMID:18712175 RGD:401827276 NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822 		JBrowse link
G Ybx1 Y box binding protein 1 IEP RGD PMID:16002047 RGD:1580630 NCBI chr 5:138,167,444...138,188,155
Ensembl chr 5:138,167,444...138,184,188 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 IEP protein:increased expression:heart (rat) RGD PMID:24155330 RGD:155882536 NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:49,624,028...49,754,323 		JBrowse link
myocardial stunning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16317512 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11927517 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Pln phospholamban ISO CTD Direct Evidence: marker/mechanism CTD PMID:16317512 NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11927517 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
No-Reflow Phenomenon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh5 cadherin 5 ISO CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822 		JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Jup junction plakoglobin ISO CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,800,814...85,827,429 		JBrowse link
Prinzmetal angina term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:plasma RGD PMID:9415270 RGD:8547713 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISO RGD PMID:11984590 RGD:1581700 NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531 		JBrowse link
ST Elevation Myocardial Infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A treatment ISO DNA:SNPs: :rs1045642,rs7779562(human) RGD PMID:25217066 RGD:14700903 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 severity ISO RGD PMID:27441480 RGD:14696800 NCBI chr 7:135,669,847...135,680,839
Ensembl chr 7:135,669,848...135,678,231 		JBrowse link
G Ccn1 cellular communication network factor 1 sexual_dimorphism ISO protein:increased expression:blood serum (human) RGD PMID:34597881 RGD:329845519 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Mir208a microRNA 208a severity IEP miRNA:increased expression:blood RGD PMID:32458401 RGD:213230165 NCBI chr15:32,395,552...32,395,634 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 0
      cardiovascular system disease 5558
        heart disease 3483
          Myocardial Ischemia 951
            Coronary Disease 629
              Coronary Occlusion 2
              Coronary-Subclavian Steal Syndrome 0
              coronary aneurysm 5
              coronary artery disease + 603
              coronary stenosis + 38
Path 2
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 0
      cardiovascular system disease 5558
        vascular disease 4039
          ischemia 1506
            Myocardial Ischemia 951
              Coronary Disease 629
                Coronary Occlusion 2
                Coronary-Subclavian Steal Syndrome 0
                coronary aneurysm 5
                coronary artery disease + 603
                coronary stenosis + 38
paths to the root