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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Coronary Disease
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Accession:DOID:9000528 term browser browse the term
Definition:An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Synonyms:exact_synonym: CORONARY ARTERY DISEASE, EARLY-ONSET;   Coronary Diseases;   coronary heart disease;   coronary heart diseases
 narrow_synonym: THREE VESSEL CORONARY DISEASE;   chronic coronary heart disease
 related_synonym: CHDS1;   CHDS2;   CHDS3;   CHDS4;   CHDS5;   CHDS6;   CHDS7;   CHDS8;   CHDS9;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 1;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 2;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 3;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 4;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 5;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 6;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 7;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 8;   CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 9;   Coronary artery disease, susceptibility to;   Coronary heart disease in familial hypercholesterolemia, protection against
 primary_id: MESH:D003327
 alt_id: OMIM:300464;   OMIM:607339;   OMIM:608316;   OMIM:608318;   OMIM:608901;   OMIM:610938;   OMIM:611139;   OMIM:612030;   OMIM:614466;   RDO:0005276
For additional species annotation, visit the Alliance of Genome Resources.


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Coronary Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO ClinVar Annotator: match by term: Coronary heart disease in familial hypercholesterolemia, protection against
ClinVar Annotator: match by term: Early-onset coronary artery disease
ClinVar PMID:11238261 PMID:12624133 PMID:16372134 PMID:16429166 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:8170965, PMID:9488209 RGD:8142364 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :8790G>A (human) RGD PMID:18753062 RGD:2313798 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ada adenosine deaminase ISO protein:increased expression:leukocyte RGD PMID:17259686 RGD:1624286 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ISO protein:decreased activity:plasma (human)
ClinVar Annotator: match by term: Three Vessel Coronary Disease
ClinVar PMID:25741868, PMID:12670342 RGD:10449044 NCBI chr 3:5,519,921...5,558,390
Ensembl chr 3:5,519,990...5,558,166
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 8:97,535,777...97,575,661
Ensembl chr 8:97,535,777...97,575,655
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression ISO associated with Diabetes mellitus, Type2; RGD PMID:22207678, PMID:22019747 RGD:5686379, RGD:5686406 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO DNA:polymorphism: :p.Q27E RGD PMID:12682000 RGD:1601128 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 susceptibility ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994(human) RGD
GAD
PMID:10421225, PMID:20536507, PMID:15118671 RGD:1559326, RGD:5684776, RGD:1331525 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO protein:decreased expression:plasma (human)
associated with Heart Failure; protein:increased expression:plasma (human)
RGD PMID:23396398, PMID:20685687 RGD:7243186, RGD:7244134 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association
ISO DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human)
RGD PMID:9456365, PMID:9857918 RGD:1601152, RGD:1566499 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Apoa4 apolipoprotein A4 susceptibility
no_association
ISO DNA:missense mutation:cds:p.T347S (human) RGD PMID:12676816, PMID:9013087 RGD:1578411, RGD:5685683 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apob apolipoprotein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17658632 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc2 apolipoprotein C2 susceptibility ISO RGD PMID:7590197 RGD:1601205 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Apoc3 apolipoprotein C3 no_association
susceptibility
ISO DNA:polymorphism:promoter:-482C>T
ClinVar Annotator: match by term: Coronary heart disease
associated with Diabetes Mellitus, Non-Insulin-Dependent
ClinVar PMID:19074352 PMID:24941081 PMID:24941082 PMID:25962519 PMID:28406212, PMID:16321685, PMID:17654446 RGD:1601224, RGD:2306754 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E onset ISO DNA:polymorphisms, haplotype:promoter, cds:g.-219G>T, p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10736278 PMID:11862316, PMID:11862316 RGD:1578479, RGD:1578479 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Ccdc92 coiled-coil domain containing 92 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:37,210,735...37,237,848
Ensembl chr12:37,211,316...37,237,848
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 resistance ISO DNA:polymorphisms:multiple (human) RGD PMID:16055130 RGD:1581176 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule ISO protein:increased expression:monocyte RGD PMID:10831941 RGD:2314175 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule susceptibility ISO mRNA:increased expression:monocyte
CTD Direct Evidence: marker/mechanism
CTD
OMIM
PMID:18067591 RGD:6893507 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40lg CD40 ligand treatment IDA RGD PMID:23819214 RGD:7248750 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 susceptibility ISO DNA:polymorphism: :p.V249I (human)
ClinVar Annotator: match by term: CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 1
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:25741868, PMID:11532900 RGD:4891901 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD PMID:10488959 RGD:1580275 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 resistance ISO DNA:polymorphism:promoter:-50G>T (human) RGD PMID:17429317 RGD:1625377 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 6:145,784,893...146,099,212
Ensembl chr 6:145,785,275...146,099,053
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:16595607 RGD:1580981 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17367797 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F12 coagulation factor XII ISO protein:decreased activity:: RGD PMID:18021303 RGD:11041785 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO RGD PMID:11391716 RGD:1581030 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:15451784 RGD:2315870 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:serum RGD PMID:16772340 RGD:2315604 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:14592833 RGD:1580433 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase disease_progression ISO RGD PMID:15809366 RGD:5508474 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:15869055 RGD:1598404 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hp haptoglobin severity ISO RGD PMID:16673012 RGD:1626344 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNPs: : -110A>C (rs1008438), 190G>C (rs1043618) (human) RGD PMID:19333379 RGD:7257652 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:12059985 RGD:1624217 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit ISO RGD PMID:15521962 RGD:1626121 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO RGD PMID:15521962 RGD:1626121 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il18 interleukin 18 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta ISO DNA:polymorphism RGD PMID:15379752 RGD:1626636 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Irs1 insulin receptor substrate 1 ISO ClinVar Annotator: match by term: Coronary artery disease, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:1311924 PMID:7623569 PMID:8104271 PMID:8647950 PMID:10084586 PMID:10430617 PMID:10591678 PMID:10843189 PMID:12843189 PMID:14671192 PMID:14707024 PMID:15240653 PMID:28869590 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:9684730 RGD:1582306 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:polymorphism:exon RGD PMID:10583927 RGD:5128478 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Kalrn kalirin, RhoGEF kinase ISO ClinVar Annotator: match by OMIM:608901
ClinVar Annotator: match by term: CORONARY ARTERY DISEASE, EARLY-ONSET
ClinVar PMID:17357071 PMID:25741868 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Kat2b lysine acetyltransferase 2B severity ISO DNA:snp:promoter:g.-2481G>C (human) RGD PMID:21062767 RGD:9590309 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 no_association ISO RGD PMID:12964027 RGD:1581699 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kdr kinase insert domain receptor ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Ldlr low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Three Vessel Coronary Disease
ClinVar Annotator: match by term: Early-onset coronary artery disease
CTD
ClinVar
PMID:9430375 PMID:9712531 PMID:10422804 PMID:11810272 PMID:11845603 PMID:17765246 PMID:19318025 PMID:20506408 PMID:21382890 PMID:21642693 PMID:23375686 PMID:24033266 PMID:25647241 PMID:25741868 PMID:28161202 PMID:28492532 PMID:28895539 PMID:29353225 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lgals2 galectin 2 susceptibility ISO RGD PMID:17040205 RGD:1581853 NCBI chr 7:120,071,122...120,077,612
Ensembl chr 7:120,071,124...120,077,612
JBrowse link
G Lipc lipase C, hepatic type susceptibility ISO associated with Obesity and Diabetes; DNA:transition:promoter:-514C>T (human) RGD PMID:16570154 RGD:2308824 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lpl lipoprotein lipase IEP
ISO
ClinVar Annotator: match by term: Coronary heart disease ClinVar PMID:8199176 PMID:8541837 PMID:8872057 PMID:10364086 PMID:10517255 PMID:21146168 PMID:24033266, PMID:27000070 RGD:13794381 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO RGD PMID:15121769 RGD:1581911 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Maco1 macoilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 5:153,122,780...153,184,940
Ensembl chr 5:153,122,781...153,184,940
JBrowse link
G Mb myoglobin severity ISO RGD PMID:15976963 RGD:1582388 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mgp matrix Gla protein susceptibility ISO RGD PMID:16973975 RGD:1582502 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mif macrophage migration inhibitory factor IEP coronary occlusion; mRNA:increased expression:myocardium RGD PMID:20367970 RGD:4890973 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:14499230 RGD:1582537 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp3 matrix metallopeptidase 3 susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD
NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16792904 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mttp microsomal triglyceride transfer protein susceptibility ISO DNA:polymorphism:promoter:-493G>T RGD PMID:15136504 RGD:1625487 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Myh15 myosin, heavy chain 15 ISO DNA:snp:exon:EX28T>C rs3900940 (human) RGD PMID:18073581 RGD:2317145 NCBI chr11:54,205,771...54,344,662
Ensembl chr11:54,204,775...54,344,615
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 susceptibility ISO DNA:missense mutation, nonsense mutations:cds:p.R46L, p.Y142X, p.C679X (human) RGD PMID:16554528 RGD:1581000 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar PMID:8532023 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pla2g7 phospholipase A2 group VII ISO CTD Direct Evidence: marker/mechanism CTD PMID:21356620, PMID:15699277 RGD:6482780 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:1730212 PMID:9181759 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pltp phospholipid transfer protein susceptibility ISO protein:increased expression:serum (human) RGD PMID:14695459 RGD:1581038 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pon1 paraoxonase 1 severity
no_association
ISO protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, susceptibility to
DNA:missense mutation:cds:p.Q192R (human)
associated with Diabetes Mellitus, Type 2;DNA:missense mutation:cds:p.Q192R (human)
CTD
ClinVar
PMID:7916578 PMID:8098250 PMID:8675673 PMID:8770857 PMID:9011577 PMID:9215303 PMID:9385372 PMID:9443884 PMID:9661650 PMID:11238489 PMID:11335891 PMID:11788650 PMID:11810302 PMID:11888590 PMID:11889198 PMID:11918623 PMID:12082503 PMID:15241482 PMID:16353344 PMID:16882531 PMID:21170047, PMID:19005291, PMID:15214960, PMID:9215303 RGD:2313267, RGD:8547675, RGD:1580201 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 susceptibility ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:9443862 RGD:1580216 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Retn resistin ISO protein:increased expression:blood RGD PMID:17175295 RGD:7207156 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO RGD PMID:15967843 RGD:1580004 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Selp selectin P ISO protein:altered expression:serum RGD PMID:11597943 RGD:1580074 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpinf2 serpin family F member 2 ISO protein:increased expression:blood RGD PMID:15771120 RGD:1625529 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
G Tert telomerase reverse transcriptase ISO ClinVar Annotator: match by term: Coronary artery disease, susceptibility to ClinVar PMID:16890917 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Thbd thrombomodulin ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:plasma RGD PMID:17200788 RGD:2312456 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16549638 NCBI chr 1:199,338,785...199,341,306
Ensembl chr 1:199,337,138...199,341,302
JBrowse link
G Vwf von Willebrand factor ISO RGD PMID:11864703 RGD:1580647 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 4:57,684,678...57,706,613
Ensembl chr 4:57,684,678...57,706,613
JBrowse link
acute myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO RGD PMID:26476955 RGD:11552746 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO mRNA:decreased expression:blood: RGD PMID:27746059 RGD:13524557 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP RGD PMID:26591365 RGD:13792778 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il33 interleukin 33 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:29689569 RGD:25823140 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Serping1 serpin family G member 1 ISO
IEP
mRNA:increased expression:heart RGD PMID:26476955, PMID:26476955 RGD:11552746, RGD:11552746 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
anterolateral myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO protein:increased expression:aortic root, coronary sinus, plasma (human) RGD PMID:12581682 RGD:8661757 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Serpine1 serpin family E member 1 disease_progression ISO protein:decreased expression, decreased activity:heart: RGD PMID:12615902, PMID:12615902 RGD:13208541, RGD:13208541 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
Cardiogenic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19337937 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21062213 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
coronary aneurysm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with Mucocutaneous Lymph Node Syndrome;protein:increased expression:serum RGD PMID:22683371 RGD:8694456 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15548583 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18084290 NCBI chr 1:84,018,857...84,040,433
Ensembl chr 1:84,018,859...84,040,433
JBrowse link
G Mill1 MHC I like leukocyte 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10899738 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:12103254 RGD:1582363 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
coronary artery disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD
GAD
PMID:11086027, PMID:15118671 RGD:1600951, RGD:1331525 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 ISO DNA:nonsense mutation:exon:p.R1141X (3421C>T) (human) RGD PMID:12176944 RGD:11038788 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 PMID:11138003 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :41A>G, 734C>T, IVS4-57_58ins48bp RGD PMID:16195894 RGD:1601112 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:14989558, PMID:12975417, PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acp1 acid phosphatase 1 ISO RGD PMID:19246900 RGD:2313179 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:97,535,777...97,575,661
Ensembl chr 8:97,535,777...97,575,655
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:adipose tissue RGD PMID:17878891 RGD:5686802 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adrb3 adrenoceptor beta 3 no_association ISO DNA:missense mutation:cds:p.W64R (human)
DNA:missense mutation:cds:p.W64R rs4994 (human)
RGD PMID:9126344, PMID:11229427 RGD:1559325, RGD:5684412 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378986 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO DNA:polymorphism:cds:p.G82S (human)
associated with Mucocutaneous Lymph Node Syndrome
RGD PMID:20668462, PMID:22337222 RGD:6767569, RGD:8695960 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility ISO DNA:polymorphism:3' utr:1166A>C RGD
GAD
PMID:12975417, PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahsg alpha-2-HS-glycoprotein susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:SNPs RGD PMID:17062776, PMID:17062776 RGD:1625792, RGD:1625792 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:18054314 RGD:5509083 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO DNA:snps:multiple (human) RGD PMID:19596330 RGD:2313883 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr20:7,484,550...7,636,498
Ensembl chr20:7,484,550...7,636,497
JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:12714198 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit ISO DNA:SNP:CDS:p.F217L (rs1047552) (human) RGD PMID:18987747 RGD:13703124 NCBI chr 8:72,508,008...72,598,921
Ensembl chr 8:72,476,425...72,629,265
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400, PMID:2128269, PMID:15118671 RGD:1601188, RGD:1331525 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa2 apolipoprotein A2 ISO protein:decreased expression:serum RGD PMID:17923573 RGD:2313956 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoa5 apolipoprotein A5 no_association ISO DNA:polymorphism:promoter:-1131T>C (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-1131T>C, c.56C>G (human)
CTD PMID:24097064, PMID:15177130, PMID:15306190 RGD:2313322, RGD:1578412 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apob apolipoprotein B no_association ISO RGD
GAD
PMID:9585673, PMID:15118671, PMID:1732399 RGD:1578418, RGD:1331525, RGD:1578417 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc3 apolipoprotein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064, PMID:14709372, PMID:15118671, PMID:15059615 RGD:1578443, RGD:1331525, RGD:1626412 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E susceptibility ISO
IMP
DNA:snp, missense mutation:promoter, cds:g.-219G>T, p.C112R (human)
associated with Diabetes Mellitus, Non-Insulin Dependent;DNA:SNP:promoter:-219G>T (human)
DNA:missense mutation:cds:p.C112R (human)
RGD
GAD
PMID:14563588, PMID:28808185, PMID:15118671, PMID:15059615, PMID:12860263 RGD:1580039, RGD:13703132, RGD:1331525, RGD:1626412, RGD:1578449 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apom apolipoprotein M susceptibility ISO DNA:SNP:promoter:g.-778T>C(rs805296)(human) RGD PMID:17674965 RGD:2314241 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G Ar androgen receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17852836 RGD:2306777 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO DNA:SNP: :rs12732361(human), associated with male. RGD PMID:27461004 RGD:14398490 NCBI chr13:63,526,486...63,959,390
Ensembl chr13:63,526,486...63,959,332
JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO associated with Mucocutaneous Lymph Node Syndrome; DNA:SNP: :rs 2395158(human) RGD PMID:19882345 RGD:9685030 NCBI chr20:4,140,184...4,156,365
Ensembl chr20:4,141,878...4,154,978
JBrowse link
G Cbs cystathionine beta synthase ISO CBS variant c.844ins68 RGD PMID:12855221 RGD:1600626 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
protein:increased expression:myocardium (rat)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, modifier of
protein:increased expression:serum (human)
CTD
ClinVar
PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:16934270 PMID:18940815, PMID:16297799, PMID:9537339 RGD:8549513, RGD:8549577 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:16620281 RGD:11081161 NCBI chr12:24,157,182...24,161,870
Ensembl chr12:24,158,766...24,161,869
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:12742282 RGD:5508477 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12426226 RGD:1581178
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:heart (rat) RGD PMID:17449418 RGD:4890438 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule no_association ISO DNA:SNP:promoter RGD PMID:18157711 RGD:2314154 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd40lg CD40 ligand ISO
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome;DNA:SNP: :rs4810485 (human)
protein:increased expression:coronary artery, serum
associated with Kidney Failure, Chronic
CTD PMID:16368305, PMID:17635572, PMID:22645426, PMID:23819214, PMID:16494885 RGD:2314209, RGD:8547776, RGD:7248750, RGD:7248436 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cdh5 cadherin 5 ISO RGD PMID:14695457 RGD:1598391 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104008 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:31358993 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782
JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:17627189 RGD:4892665 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Clcn6 chloride voltage-gated channel 6 susceptibility ISO DNA:SNP: :rs3737964(human) RGD PMID:26740945 RGD:14696742 NCBI chr 5:164,811,815...164,844,554
Ensembl chr 5:164,811,816...164,844,586
JBrowse link
G Clu clusterin ISO associated with Mucocutaneous Lymph Node Syndrome;protein:decreased expression:plasma RGD PMID:20711835 RGD:9068393 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Crp C-reactive protein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:24868163, PMID:19615354 RGD:2313344 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cst3 cystatin C ISO protein:increased expression:serum (human) RGD PMID:17983622 RGD:2314352 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD
GAD
PMID:14709372, PMID:15118671 RGD:1578443, RGD:1331525 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17267746 NCBI chr20:5,049,260...5,052,573
Ensembl chr20:5,049,496...5,052,585
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO protein:increased expression:smooth muscle cell,macrophage RGD PMID:10973835, PMID:8994440 RGD:1580909, RGD:7244168 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 treatment
severity
ISO
IMP
protein:increased expression:atherosclerotic lesions (human)
associated with Hypertension;DNA:missense mutation:cds:p.L198N (human)
RGD PMID:7968078, PMID:11927217, PMID:18923236 RGD:4144886, RGD:8662294, RGD:8661705 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eng endoglin severity ISO protein:increased expression:plasma (human) RGD PMID:21667051 RGD:7248776 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:14732757 RGD:1580982 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:25245553 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:SNP: :rs13181(human) RGD PMID:27566080 RGD:12880440 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9396482 PMID:20559769, PMID:16159931 RGD:1580335 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20559769, PMID:16099331 RGD:1581014 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F2 coagulation factor II treatment ISO RGD PMID:14961168 RGD:10449426 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:plasma (human)
DNA:polymorphisms:cds:R353Q (human)
RGD PMID:10599031, PMID:8522401, PMID:11334615 RGD:2312400, RGD:2312408, RGD:2312397 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fabp2 fatty acid binding protein 2 ISO associated with Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:15059615 RGD:1626412 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO DNA:polymorphism: :p.H131R (human) RGD PMID:20973705 RGD:5147917 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa susceptibility ISO DNA:SNP:exon:p.F158V (rs396991)(human) RGD PMID:15910853 RGD:5508464 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fgb fibrinogen beta chain ISO RGD PMID:8565160 RGD:1580382 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:14585103 RGD:2315879 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gck glucokinase susceptibility ISO DNA:SNP:promoter:-30G>A (human) RGD PMID:15173029 RGD:2301876 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15059615 RGD:1626412 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221
JBrowse link
G Gnb3 G protein subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16141801 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics
DNA:repeat:exon
RGD PMID:16338763, PMID:12655278 RGD:1600708, RGD:1600677 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics RGD PMID:16338763 RGD:1600708 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion
RGD PMID:19102712, PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion
RGD PMID:19102712, PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr12:40,712,078...40,860,930
Ensembl chr12:40,713,841...40,822,159
JBrowse link
G Hfe homeostatic iron regulator no_association ISO RGD PMID:12746412 RGD:1582673 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:11669408 RGD:8548610 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hhipl1 HHIP-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 6:132,218,583...132,242,852
Ensembl chr 6:132,219,088...132,240,356
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:12742282 RGD:5508477 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 no_association
susceptibility
ISO DNA:repeat:promoter
CTD Direct Evidence: marker/mechanism
CTD PMID:12136229, PMID:14691581, PMID:12377749, PMID:12136229 RGD:1580470, RGD:1580454, RGD:1598401 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin ISO protein:increased expression:serum RGD PMID:884791 RGD:1626363 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:15266341 PMID:15965027 PMID:16024819 PMID:16410828 PMID:17179217 PMID:17558387 PMID:17568005 PMID:19122651 PMID:19303047 PMID:19858363 PMID:21152010 PMID:22090374 PMID:28126521 NCBI chr14:75,880,410...75,881,346
Ensembl chr14:75,852,060...75,882,693
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 severity ISO RGD PMID:11222468 RGD:1624218 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Il10 interleukin 10 no_association
susceptibility
ISO DNA:SNPs:promoter:-592C>A (rs1800872), -819C>T (rs1800871) (human)
DNA:SNP:promoter:-1082A>G (rs1800896) (human)
RGD PMID:16460885, PMID:29525679, PMID:29525679 RGD:1598621, RGD:14975129, RGD:14975129 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il15 interleukin 15 ISO associated with Hypertension;protein:increased expression:serum RGD PMID:16109314 RGD:1626610 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il1b interleukin 1 beta ISO mRNA:increased expression:peripheral blood (human) RGD PMID:22780915 RGD:7175093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO DNA:polymorphisms: :-27307T>A, -27614C>A (human) RGD PMID:20602249 RGD:5144241 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il6 interleukin 6 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human) RGD PMID:19368923 RGD:2307251 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Irs1 insulin receptor substrate 1 ISO DNA:polymorphism:exon:G972R
CTD Direct Evidence: marker/mechanism
CTD PMID:10591678, PMID:10591678 RGD:1624974 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:15227729 RGD:1582294 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Jcad junctional cadherin 5 associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr17:55,667,754...55,709,738
Ensembl chr17:55,670,331...55,709,740
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592
JBrowse link
G Kl Klotho ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter: -G395>A (human)
CTD PMID:12669274, PMID:16979405, PMID:16579981 RGD:1581721, RGD:1581723 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Ldlr low density lipoprotein receptor no_association ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400, PMID:16459141 RGD:1581823 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:SNP:cds:p.Q223R(human) RGD PMID:27257426 RGD:21079462 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lipa lipase A, lysosomal acid type ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G Lipc lipase C, hepatic type no_association ISO associated with Diabetes Mellitus, Insulin-Dependent; DNA:transition:promoter:-480C>T (human) RGD
GAD
PMID:11916946, PMID:15118671, PMID:12689525, PMID:15099346 RGD:2308839, RGD:1331525, RGD:1600664, RGD:1600663 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lipg lipase G, endothelial type ISO RGD PMID:16354105 RGD:1580865 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lmod1 leiomodin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228
JBrowse link
G LOC102551309 uncharacterized LOC102551309 ISO DNA:SNP: :rs56001051(human) RGD PMID:31175347 RGD:14696712 NCBI chr 5:164,875,558...164,885,606
Ensembl chr 5:164,874,832...164,883,933
JBrowse link
G Lox lysyl oxidase IDA RGD PMID:12393934 RGD:1581886 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpl lipoprotein lipase ISO RGD PMID:8641022 RGD:1580537 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp6 LDL receptor related protein 6 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
onset
ISO DNA:missense mutation:cds:p.R952Q (human) RGD PMID:18592168, PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15266304, PMID:15973460 RGD:1580414 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Lum lumican ISO RGD PMID:11890723 RGD:1582121 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Mef2a myocyte enhancer factor 2a ISO
ISS
OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO PMID:15811259 RGD:1580548 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr13:101,727,434...101,770,127
Ensembl chr13:101,727,935...101,761,541
JBrowse link
G Mir146a microRNA 146a ISO CTD Direct Evidence: marker/mechanism
miRNA:increased expression:peripheral blood mononuclear cell, plasma
CTD PMID:20524934, PMID:31866771 RGD:21081515 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir146b microRNA 146b ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir223 microRNA 223 treatment ISO RGD PMID:25350775 RGD:11076984 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mmp1 matrix metallopeptidase 1 severity ISO DNA:insertion, haplotype:promoter:g.-1607insG rs799750 (human) RGD PMID:15619398, PMID:17893005 RGD:1582527, RGD:7207049 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:10807873 RGD:1582366 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO DNA:insertion, haplotype:promoter:g.-1613insA rs3025058 (human)
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome
CTD PMID:8662692, PMID:17893005, PMID:16100452 RGD:7207049, RGD:8693322 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility
treatment
ISO
IEP
RGD PMID:15191941, PMID:26261622 RGD:1582644, RGD:11344965 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr11:32,208,246...32,263,999
Ensembl chr11:32,211,115...32,263,899
JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association
susceptibility
ISO DNA:transition:cds:g.677C>T (human) RGD PMID:15648053, PMID:12387655 RGD:1580579, RGD:6893453 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO RGD PMID:17283255 RGD:1642340 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nat2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21572414 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ngf nerve growth factor ISO RGD PMID:11935372 RGD:1580935 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:11935372 RGD:1580935 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO DNA:polymorphisms: :p.G908R, 3020_3021insC (human) RGD PMID:21565239 RGD:5508725 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with Mucocutaneous Lymph Node Syndrome; protein:increased expression:neutrophil, monocyte RGD PMID:14764920 RGD:1580941 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:g.-786T>C (human)
DNA:snp:cds:c.894G>T (human)
CTD PMID:10510054 PMID:14989558 PMID:17267746 PMID:19696404, PMID:8564837, PMID:19761682, PMID:16284093 RGD:7421529, RGD:7771578, RGD:7771567 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A ISO DNA:snp:cds:c.2238T>C (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP:exon: 2238T>C,rs5065 (human)
RGD PMID:12514664, PMID:22170009 RGD:1579982, RGD:7247716 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18022110 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:missense mutation:cds:p.N363S (human) RGD PMID:12623935 RGD:1580790 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 severity ISO DNA:snp:3' utr:T>C (human)
DNA:missense mutation:cds:p.K167N (human)
RGD PMID:12810610, PMID:15562935 RGD:1580995, RGD:1580994 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Pappa1 pappalysin 1 severity ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954, PMID:16055491 RGD:1642327 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Parl presenilin associated, rhomboid-like susceptibility ISO DNA:missense mutation:cds:p.L262V (human) RGD PMID:18758826 RGD:12902623 NCBI chr11:84,517,368...84,544,463
Ensembl chr11:84,517,368...84,544,462
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pdgfd platelet derived growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 no_association ISO DNA:missense mutations:cds:p.N536S, p.G670R (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.L125V (human)
DNA:polymorphism:5' utr:g.53G>A (human)
CTD PMID:28530674, PMID:11795274, PMID:10780329, PMID:12732396 RGD:2311656, RGD:6771225, RGD:1581010 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Phactr1 phosphatase and actin regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:22751097 PMID:26098115 NCBI chr17:23,245,423...23,761,207 JBrowse link
G Pla2g7 phospholipase A2 group VII disease_progression
susceptibility
ISO DNA:polymorphism: :p.A379V (human) RGD PMID:17070179, PMID:15115767 RGD:6482777, RGD:6482781 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plpp3 phospholipid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:31377187 RGD:14981594 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.Q192R (human)
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Coronary artery spasm 2, susceptibility to
protein:increased activity:serum (human)
CTD
ClinVar
PMID:7916578 PMID:8098250 PMID:8675673 PMID:8770857 PMID:9215303 PMID:9385372 PMID:9443884 PMID:11238489 PMID:11810302 PMID:11888590 PMID:12082503 PMID:15241482 PMID:21170047 PMID:21629682, PMID:10729395, PMID:15785307, PMID:11917194 RGD:1580196, RGD:8547681, RGD:1580203 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 severity ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:12454802 RGD:1580217 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO DNA:snp:intron: (human) RGD PMID:16043164 RGD:1580228 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:decreased expression:carotid artery, macrophage, smooth muscle cell (human) RGD PMID:21709632 RGD:8552814 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632
JBrowse link
G Procr protein C receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14642682 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human) RGD PMID:23460043 RGD:7242420 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO DNA: snp: cds: rs2476601 RGD PMID:21846984 RGD:6484553 NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
JBrowse link
G Sele selectin E susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:mutation: :p.S128R (human) RGD PMID:17578587 RGD:2313596 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Selp selectin P ISO ClinVar Annotator: match by term: Premature coronary artery disease ClinVar NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina1 serpin family A member 1 ISO protein:increased expression:serum RGD PMID:7832094 RGD:1643149 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:insertion:promoter: (human) RGD PMID:9484978 RGD:1580190 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf2 serpin family F member 2 ISO RGD PMID:9184412 RGD:1625532 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Soat2 sterol O-acyltransferase 2 susceptibility ISO DNA:polymorphisms: :p.E41G, p.T734I, IVS4-57_-58ins48bp (human) RGD PMID:16195894 RGD:1601112 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989
JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:10811593 RGD:1580853 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sort1 sortilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO In type 2 diabetic patients RGD PMID:21034455 RGD:6903271 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO GAD PMID:15118671 RGD:1331525 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tcf21 transcription factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:22751097 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Tek TEK receptor tyrosine kinase ISO protein:increased expression:plasma RGD PMID:12814387 RGD:1601489 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16890917 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thbd thrombomodulin severity ISO RGD PMID:17012137 RGD:1601638 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934, PMID:15632890 RGD:1580736 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:15059615 RGD:1626412 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15926884 RGD:1620893 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A severity ISO RGD PMID:19845893 RGD:5131425 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnni3 troponin I3, cardiac type ISO RGD PMID:12221049 RGD:1580780 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tp53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human) RGD PMID:29482350 RGD:14995930 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Trib1 tribbles pseudokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Ttn titin ISO RGD PMID:12221049 RGD:1580780 NCBI chr 3:63,565,160...63,837,815 JBrowse link
G Vdr vitamin D receptor severity ISO DNA:SNP (human) RGD PMID:9761785 RGD:4889864 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14668888 PMID:15937083, PMID:15754021 RGD:1580569 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin ISO protein:increased expression:monocyte RGD PMID:21938407 RGD:6480617 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vtn vitronectin ISO RGD PMID:15678274 RGD:1580816 NCBI chr10:65,767,960...65,771,040
Ensembl chr10:65,767,053...65,771,038
JBrowse link
G Wdr12 WD repeat domain 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 9:66,851,499...66,878,534
Ensembl chr 9:66,851,940...66,877,972
JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:11186893 RGD:1580824 NCBI chr16:62,483,773...62,619,018
Ensembl chr16:62,483,761...62,615,375
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:57,684,678...57,706,613
Ensembl chr 4:57,684,678...57,706,613
JBrowse link
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a ISO ClinVar Annotator: match by term: Coronary artery disease/myocardial infarction
ClinVar Annotator: match by OMIM:608320
OMIM
ClinVar
PMID:14645853 PMID:15496429 PMID:15841183 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2
ClinVar Annotator: match by OMIM:610947
OMIM
ClinVar
PMID:17332414 PMID:23703864 PMID:25741868 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
Coronary Artery Disease, Development of, in HIV term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO ClinVar Annotator: match by null ClinVar PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:18940815 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
coronary artery vasospasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap9 Rho GTPase activating protein 9 ISO ClinVar Annotator: match by term: Coronary artery spasm 3, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:19911011 NCBI chr 7:70,612,650...70,620,900
Ensembl chr 7:70,612,103...70,620,890
JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Coronary artery spasm 1, susceptibility to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:9737779 PMID:9894802 PMID:10359729 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11810302 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
Coronary Occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 disease_progression ISO RGD PMID:26315408 RGD:14367880 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO mRNA:increased expression:heart: RGD PMID:21439970 RGD:7257651 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
coronary restenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:9236417 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:12138120 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17275003 RGD:2306778 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cdh13 cadherin 13 IEP protein:increased expression:artery, smooth muscle cell RGD PMID:12376824 RGD:2293553 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:plasma RGD PMID:14578618 RGD:1598500 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:14578618 RGD:1598500 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO RGD PMID:14529396 RGD:1581036 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Hmox1 heme oxygenase 1 susceptibility ISO RGD PMID:16020495, PMID:14529548 RGD:1598402, RGD:1580472 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:11703955 RGD:1581185 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Lox lysyl oxidase IDA RGD PMID:15218472 RGD:1581881 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:15583728 RGD:1582284 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:5' utr, exon:multiple (human) RGD PMID:15790942 RGD:1582150 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8662692 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IEP RGD PMID:21139058 RGD:9685362 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16489563 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IDA RGD PMID:7955204 RGD:10059621 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Npy5r neuropeptide Y receptor Y5 IEP mRNA, protein:increased expression:carotid artery RGD PMID:12689918 RGD:1625501 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:12114325, PMID:16373617 RGD:1581358, RGD:1581366 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16319143, PMID:16319143 RGD:1580322 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 ISO RGD PMID:14740296 RGD:1580742 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ucp3 uncoupling protein 3 susceptibility ISO DNA:polymorphism:promoter:-55C>T (human) RGD PMID:17786284 RGD:2313513 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
coronary stenosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin ISO protein:decreased expression:plasma RGD PMID:19015606 RGD:2313942 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Edn1 endothelin 1 treatment ISO RGD PMID:10854676 RGD:8661796 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Igf1 insulin-like growth factor 1 IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA:increased expression:myocyte: RGD PMID:8102103 RGD:10046053 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Itgav integrin subunit alpha V IDA RGD PMID:11922905 RGD:1582454 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Mdk midkine IDA RGD PMID:10683378 RGD:1299187 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Myh7 myosin heavy chain 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721106 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO DNA:missense mutations:cds:p.L125V, p.S563N (human) RGD PMID:10571959 RGD:1598382 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:16782078 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15569000 RGD:1624167 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
coronary thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8598867 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1452937 PMID:8172379 PMID:15301905 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
Hypertension Resistant to Conventional Therapy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion:cds: (human) RGD PMID:19279659 RGD:7495846 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Hypertension resistant to conventional therapy ClinVar PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
intermediate coronary syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO mRNA:increased expression:ventricular myocardium (human)
mRNA:increased expression:myocardium
RGD PMID:15131005, PMID:11451295 RGD:8142363, RGD:8548894 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Agt angiotensinogen ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO mRNA:increased expression:myocardium RGD PMID:11451295 RGD:8548894 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:platelet RGD PMID:20467748 RGD:5509094 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:decreased expression:blood plasma (human) RGD PMID:20367977 RGD:5685646 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:16186425 RGD:4891111 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:9761079 RGD:9491780 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Edn1 endothelin 1 ISO associated with Coronary Artery Disease;protein:increased expression:coronary sinus, plasma (human) RGD PMID:14556009 RGD:8661755 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G F7 coagulation factor VII ISO protein:increased expression:plasma (human) RGD PMID:10653827 RGD:2312399 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18333374 RGD:5508458 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility ISO RGD PMID:15104219 RGD:1582303 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO RGD PMID:14675588 RGD:1582536 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Pappa1 pappalysin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:2382605 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21162967 RGD:6219003 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:8122184 RGD:11035255 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:15749180 RGD:1580784 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
Medial Coronary Sclerosis of Infancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO ClinVar Annotator: match by term: Coronary sclerosis, medial, of infancy ClinVar PMID:15940697 PMID:25741868 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar PMID:16563363 PMID:23861362 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Ace angiotensin I converting enzyme treatment
susceptibility
ISO
IEP
IMP
ClinVar Annotator: match by term: Heart attack
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Myocardial Reperfusion Injury
ClinVar
CTD
PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 PMID:2847529 PMID:2849100 PMID:7593601 PMID:7729604 PMID:7854377 PMID:7909524 PMID:8131299 PMID:8131300 PMID:8136829 PMID:8170965 PMID:8208911 PMID:8298638 PMID:8314010 PMID:8541160 PMID:8644984 PMID:8675669 PMID:9120002 PMID:9236417 PMID:9259580 PMID:9699903 PMID:9737775 PMID:9916793 PMID:10099885 PMID:10636736 PMID:10643899 PMID:10841123 PMID:11687636 PMID:11956052 PMID:12220450 PMID:12666117 PMID:14657821 PMID:14872014 PMID:15110771 PMID:15277638 PMID:15381116 PMID:15531537 PMID:15534175 PMID:15635071 PMID:19221299, PMID:15118671, PMID:23959549, PMID:15671045, PMID:7555560, PMID:21975128 RGD:1331525, RGD:9685449, RGD:1558664, RGD:7829785, RGD:6893480 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 treatment IEP
IDA
mRNA:increased expression:myocardium RGD PMID:15671045, PMID:23959549 RGD:1558664, RGD:9685449 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acta2 actin alpha 2, smooth muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:15625312 RGD:9681751 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Add1 adducin 1 no_association ISO DNA:missense mutation:cds:p.G460W (human) RGD PMID:17082469, PMID:16420563 RGD:5147995, RGD:5148001 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression IEP RGD PMID:21326342 RGD:5686351 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor1 adiponectin receptor 1 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Adipor2 adiponectin receptor 2 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora3 adenosine A3 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 PMID:20132822 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:12535806 RGD:1559314 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Adrb1 adrenoceptor beta 1 ISO
IMP
GAD
RGD
PMID:15118671, PMID:17143192 RGD:1331525, RGD:7241557 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO
IEP
DNA:polymorphisms: :p.G16R, p.Q27E, p.T164I
mRNA:decreased expression:heart
RGD PMID:15520258, PMID:12400771 RGD:1601126, RGD:8548519 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility IEP
ISO
mRNA:increased expression:left ventricle myocardium (rat)
DNA:polymorphism:promoter:-429T>C (human)
RGD PMID:19910580, PMID:16728681 RGD:2325647, RGD:1625333 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen susceptibility IDA
ISO
CTD Direct Evidence: marker/mechanism
associated with Coronary Artery Disease;DNA:polymorphism: :p.M235T (human)
associated with hypertension;DNA:polymorphism: :p.M235T
CTD PMID:1668233 PMID:16413583, PMID:21167013, PMID:15118671, PMID:11393670, PMID:17299437 RGD:5129191, RGD:1331525, RGD:1566452, RGD:1601132 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association
ISO
IEP
DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human)
RGD
GAD
PMID:16061119, PMID:9652322, PMID:15118671, PMID:9857918 RGD:1601150, RGD:10047101, RGD:1331525, RGD:1566499 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahsg alpha-2-HS-glycoprotein ISO protein:increased expression:plasma RGD PMID:19029462 RGD:2313810 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 IEP RGD PMID:14732363 RGD:1580021 NCBI chr 2:237,727,782...237,751,327
Ensembl chr 2:237,727,764...237,751,378
JBrowse link
G Ak1 adenylate kinase 1 treatment IEP RGD PMID:22229508 RGD:11100025 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO
IDA
protein:increased serine phosphorylation:platelet
protein:decreased serine phosphorylation:heart
RGD PMID:20467748, PMID:20352476 RGD:5509094, RGD:10041035 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO DNA:missense mutation: :p.E487K (human) RGD PMID:12452318 RGD:2311152 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein no_association ISO DNA:snps:multiple (human) RGD
GAD
PMID:14770184, PMID:15118671, PMID:19046748 RGD:1578317, RGD:1331525, RGD:2313891 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Ang angiogenin ISO RGD PMID:18462761 RGD:2325719 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Angpt1 angiopoietin 1 IEP mRNA, protein:decreased expression:myocardium RGD PMID:15364619 RGD:1626168 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Angpt2 angiopoietin 2 IEP protein:increased expression:left ventricular wall, heart septum (rat) RGD PMID:16714360 RGD:1601493 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Anxa5 annexin A5 susceptibility
no_association
ISO
IEP
DNA:polymorphism: :-1C>T (human)
protein:altered localization:cardiac muscle cell, sarcolemma
protein:increased expression:plasma
RGD PMID:12200370, PMID:16501019, PMID:8814351, PMID:16025836 RGD:2317542, RGD:2317541, RGD:2317543, RGD:1578384 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apoa1 apolipoprotein A1 no_association ISO DNA:polymorphisms RGD
GAD
PMID:20176799, PMID:15118671, PMID:10428310 RGD:2325759, RGD:1331525, RGD:1578442 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 no_association
susceptibility
ISO DNA:mutation:intron:IVS2 (human)
associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.Q360H (human)
RGD
GAD
PMID:10428310, PMID:7958503, PMID:15118671 RGD:1578442, RGD:5685678, RGD:1331525 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apob apolipoprotein B ISO GAD PMID:15118671 RGD:1331525 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoc3 apolipoprotein C3 no_association ISO RGD
GAD
PMID:10428310, PMID:15118671 RGD:1578442, RGD:1331525 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:missense mutations, haplotypes:cds:p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations, haplotype:cds:p.C112R, p.C158R (human)
ClinVar Annotator: match by null
CTD
ClinVar
PMID:10587578 PMID:12774036, PMID:17217375, PMID:10090925, PMID:15118671 RGD:1601229, RGD:10449412, RGD:1331525 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apoh apolipoprotein H ISO
IDA
RGD PMID:15322656, PMID:12826288 RGD:2313985, RGD:10054111 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Atg7 autophagy related 7 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atm ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288, PMID:24358288 RGD:10053570 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:29300489, PMID:23809007 RGD:13792656, RGD:13792681 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:16423716 RGD:2300376 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20079142 PMID:25450231 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:20079142, PMID:17467744 RGD:1643494 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdkrb1 bradykinin receptor B1 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Becn1 beclin 1 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:20079142, PMID:20079142 RGD:11561913 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP RGD PMID:15081314 RGD:2293137 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Brap BRCA1 associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198608 NCBI chr12:40,381,892...40,417,764
Ensembl chr12:40,383,577...40,417,654
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 susceptibility ISO DNA:SNPs:3' end: RGD PMID:18430236 RGD:14398488 NCBI chr13:63,526,486...63,959,390
Ensembl chr13:63,526,486...63,959,332
JBrowse link
G C3 complement C3 IEP mRNA, protein:increased expression:myocardium RGD PMID:16996480 RGD:1600605 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C7 complement C7 IEP Protein:increased activity:serum, myocardium RGD PMID:15724448 RGD:1599522 NCBI chr 2:54,707,621...54,781,624
Ensembl chr 2:54,709,138...54,777,729
JBrowse link
G C8a complement C8 alpha chain IEP RGD PMID:7515561 RGD:1600501 NCBI chr 5:124,348,536...124,403,117
Ensembl chr 5:124,348,461...124,403,195
JBrowse link
G C8b complement C8 beta chain IEP RGD PMID:7515561 RGD:1600501 NCBI chr 5:124,298,269...124,338,055
Ensembl chr 5:124,300,477...124,338,053
JBrowse link
G Cacybp calcyclin binding protein IEP mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Casp1 caspase 1 severity ISO RGD PMID:17303764 RGD:2315913 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:25450231, PMID:27904666 RGD:13782309 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:myocardium (rat) RGD PMID:22527939 RGD:7205672 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: therapeutic CTD PMID:21600015, PMID:14575298 RGD:1581148 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav3 caveolin 3 IEP Protein:increased expression:cytosol RGD PMID:12566108 RGD:1599542 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
IDA
ISO
protein:increased expression:serum
DNA:snp:promoter:g.-2518A>G (human)
RGD PMID:18459941, PMID:18753699, PMID:16116069 RGD:2307033, RGD:8549616, RGD:1581161 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:heart (rat) RGD PMID:18954648 RGD:4890013 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn2 cellular communication network factor 2 treatment IEP mRNA:increased expression:left ventricle (rat) RGD PMID:18167060, PMID:29849775 RGD:2314623, RGD:35673318 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 IEP protein:increased expression:cardiomyocyte: RGD PMID:23634243 RGD:10054471 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12719858, PMID:12853162 RGD:1581177, RGD:1581174
G Ccr3 C-C motif chemokine receptor 3 IDA RGD PMID:18954648 RGD:4890013 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO ClinVar Annotator: match by synonym: MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 1 ClinVar PMID:24213632 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265
JBrowse link
G Cd14 CD14 molecule no_association ISO associated with Coronary Artery Disease;DNA:SNP:promoter RGD PMID:10195920, PMID:14587643, PMID:17436151 RGD:1580252, RGD:1580255, RGD:2314155 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule severity IMP RGD PMID:22128087 RGD:6893560 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd59 CD59 molecule IEP protein:decreased expression:myocardium RGD PMID:7515561 RGD:1600501 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B treatment IMP
ISO
RGD PMID:22492676, PMID:22492676 RGD:10045366, RGD:10045366 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cfl1 cofilin 1 treatment IDA RGD PMID:24292258 RGD:11570534 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cftr CF transmembrane conductance regulator ISO associated with Myocardial Reperfusion Injury RGD PMID:23221371 RGD:11566046 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:18480670 RGD:4892633 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator susceptibility
no_association
ISO DNA:polymorphism:promoter:-168A>G (human) RGD PMID:15821736, PMID:17183695 RGD:1358146, RGD:5491201 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:12359538 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Ckm creatine kinase, M-type ISO CTD Direct Evidence: marker/mechanism CTD PMID:3279722 PMID:12359538 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Clu clusterin treatment ISO RGD PMID:20854280 RGD:9068409 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Col1a1 collagen type I alpha 1 chain treatment IEP RGD PMID:25636075 RGD:11041598 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain treatment IEP RGD PMID:25636075 RGD:11041598 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a1 collagen type IV alpha 1 chain susceptibility ISO DNA:polymorphism: :p.Q1334H (human) RGD PMID:18077766 RGD:2311341 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crp C-reactive protein IEP
ISO
protein:increased expression:serum
associated with Angina, Unstable;
RGD PMID:21046814, PMID:9761079, PMID:22446866 RGD:5131456, RGD:9491780, RGD:6482304 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf2 colony stimulating factor 2 IMP RGD PMID:21326109 RGD:5131507 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:15639484 RGD:11039417 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 IEP RGD PMID:15090263 RGD:11565830 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Csnk2b casein kinase 2 beta IEP RGD PMID:15090263 RGD:11565830 NCBI chr20:5,108,692...5,113,675
Ensembl chr20:5,106,890...5,113,112
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO DNA:SNP:CDS:49A>G (human) RGD PMID:17652883 RGD:2301976 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:serum, heart (rat) RGD PMID:19958779 RGD:2315501 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP
IMP
mRNA:increased expression:heart left ventricle RGD PMID:11820456, PMID:19187644 RGD:632503, RGD:2306567 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyba cytochrome b-245 alpha chain IEP mRNA:increased expression:myocardium
mRNA:increase expression:ventricle myocardium:
RGD PMID:18762777, PMID:11243862 RGD:2317860, RGD:1599690 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain IEP mRNA:increase expression:ventricle myocardium RGD PMID:11243862 RGD:1599690 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IMP RGD PMID:18689429 RGD:2307303 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 susceptibility ISO DNA:polymorphism RGD PMID:17126841 RGD:1625380 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Dab2 DAB adaptor protein 2 IEP
IMP
protein:increased expression:cardiomyocyte RGD PMID:21762377, PMID:20666606 RGD:7243156, RGD:7243158 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dab2ip DAB2 interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20622881 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Dag1 dystroglycan 1 treatment IDA RGD PMID:12034665 RGD:11541047 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Dcn decorin IEP RGD PMID:16311904 RGD:1598497 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dgkz diacylglycerol kinase zeta ISO CTD Direct Evidence: therapeutic CTD PMID:17071729 NCBI chr 3:80,844,002...80,886,487
Ensembl chr 3:80,844,005...80,875,817
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 IEP RGD PMID:15256074 RGD:1580899 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:9607404 RGD:1580912 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 severity ISO
IEP
protein:increased secretion:plasma (human)
mRNA:increased expression:heart left ventricle (rat)
RGD PMID:17893002, PMID:10573185 RGD:4144880, RGD:1580921 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 IEP RGD PMID:10573185 RGD:1580921 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:12524016 RGD:1580948 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B IDA RGD PMID:12524016 RGD:1580948 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IEP RGD PMID:16765982 RGD:11252084 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IEP RGD PMID:16765982 RGD:11252084 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Epas1 endothelial PAS domain protein 1 IEP RGD PMID:15247145, PMID:18484163 RGD:1580977, RGD:5147886 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:19716829 RGD:5688358 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:19337937, PMID:21415704 RGD:10400907 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor IEP RGD PMID:21415704 RGD:10400907 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Esr1 estrogen receptor 1 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by null
OMIM
CTD
ClinVar
PMID:11894143 PMID:11919305 PMID:14600184, PMID:15118671 RGD:1331525 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G F10 coagulation factor X ISO ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to ClinVar PMID:10984565 PMID:12181036 PMID:25741868 NCBI chr16:81,803,169...81,822,476
Ensembl chr16:81,803,110...81,822,716
JBrowse link
G F12 coagulation factor XII susceptibility ISO DNA:polymorphism:promoter:-46C>T(human) RGD PMID:16411408 RGD:11041803 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F13a1 coagulation factor XIII A1 chain susceptibility ISO ClinVar Annotator: match by term: Myocardial infarction, protection against
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:8025280 PMID:9459313 PMID:9550516 PMID:10365735 PMID:10910914 PMID:12072871 PMID:12456499 PMID:17393027 PMID:25741868, PMID:12480694 RGD:1581022 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G F2 coagulation factor II susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism::20210G>A(human)
CTD PMID:9292507 PMID:9531249 PMID:10027711, PMID:12480694 RGD:1581022 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F3 coagulation factor III, tissue factor treatment IEP RGD PMID:21229253 RGD:11062083 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F5 coagulation factor V no_association
susceptibility
ISO CTD Direct Evidence: marker/mechanism
DNA:mutation:cds:1691G>A (human)
CTD PMID:9531249, PMID:10590188, PMID:15131548 RGD:11564337, RGD:11564335 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G F7 coagulation factor VII susceptibility ISO protein:increased activity:plasma (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to
DNA:missense mutation, repeat:cds, intron:p.R353Q, (human)
CTD
OMIM
ClinVar
PMID:10984565 PMID:12181036 PMID:25741868, PMID:7495060, PMID:9420338, PMID:16116695 RGD:2312409, RGD:11049521, RGD:1580374 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fabp3 fatty acid binding protein 3 ISO RGD PMID:8326460 RGD:1582401 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fgb fibrinogen beta chain ISO GAD
RGD
PMID:15118671, PMID:9437197 RGD:1331525, RGD:1580381 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgf1 fibroblast growth factor 1 treatment ISO RGD PMID:24200746 RGD:10449026 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:17439742 RGD:10402087 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fis1 fission, mitochondrial 1 IEP protein:increased expression:plantaris (rat) RGD PMID:24427319 RGD:11557988 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP RGD PMID:16714360 RGD:1601493 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand treatment ISO RGD PMID:24184252 RGD:11049498 NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413
JBrowse link
G Fn1 fibronectin 1 IEP protein:decreased expression:heart RGD PMID:19695229 RGD:2325720 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fzd2 frizzled class receptor 2 IEP mRNA:increased expression:heart left ventricle RGD PMID:9142123 RGD:4107058 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:20462747 RGD:10449173 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gata4 GATA binding protein 4 treatment IMP
ISO
CTD Direct Evidence: therapeutic CTD PMID:20200331, PMID:23948075 RGD:7327215 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit susceptibility ISO DNA:snp:promoter:c.-129C>T (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by null
OMIM
CTD
ClinVar
PMID:12598062, PMID:12598062 RGD:1302515 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit susceptibility ISO ClinVar Annotator: match by null
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:12081989 PMID:12975258 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19419996 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gh1 growth hormone 1 treatment ISO RGD PMID:12500159 RGD:11352745 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghrh growth hormone releasing hormone treatment IDA RGD PMID:24373935 RGD:10401242 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP
IMP
protein:decreased phosphorylation RGD PMID:22969867, PMID:29428663, PMID:22841862 RGD:7207261, RGD:13592597, RGD:7207262 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15982495 RGD:1580400 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221
JBrowse link
G Gja5 gap junction protein, alpha 5 treatment IEP RGD PMID:29428663 RGD:13592597 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:15269835 RGD:1580432 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO RGD PMID:14573732 RGD:1600662 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16716347, PMID:16565311 RGD:10045368 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:25119867 RGD:10401898 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO ClinVar Annotator: match by synonym: MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 1 ClinVar PMID:24213632 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEP RGD PMID:11481570 RGD:2302229 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA:increased expression:heart RGD PMID:19615879 RGD:11041636 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hfe homeostatic iron regulator no_association
susceptibility
ISO RGD PMID:12850485, PMID:10491370 RGD:1582672, RGD:1582697 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hgf hepatocyte growth factor treatment ISO protein:increased expression:serum: RGD PMID:12419930, PMID:16570015 RGD:8548609, RGD:8548632 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP
ISO
mRNA:increased expression:heart left ventricle
human gene in a rat model
RGD PMID:18484163, PMID:15247145, PMID:15999059 RGD:5147886, RGD:1580977, RGD:9068466 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb1 high mobility group box 1 treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:21113057, PMID:23188125 RGD:10402174 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 IEP
IDA
RGD PMID:12392996, PMID:20925964 RGD:1598393, RGD:4145134 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin susceptibility ISO CTD Direct Evidence: marker/mechanism CTD PMID:16597321 PMID:17068284 PMID:17207726, PMID:3990081, PMID:2613263 RGD:1626360, RGD:1626354 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IEP
ISO
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
CTD PMID:17587755, PMID:17587755 RGD:2308939 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:17202668 RGD:1624230 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:10070497, PMID:23139358 RGD:8547733 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Igf1 insulin-like growth factor 1 severity IEP
ISO
mRNA, protein:increased expression:myocardium RGD PMID:19295919, PMID:16635594 RGD:2306696, RGD:1598421 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA,protein:increased expression:myocyte: RGD PMID:8682060 RGD:10046050 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il10 interleukin 10 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD PMID:15883752 PMID:16310260, PMID:15466015 RGD:1598480 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il17a interleukin 17A IEP mRNA, protein:increased expression:heart left ventricle (rat) RGD PMID:23096364 RGD:9095344 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18bp interleukin 18 binding protein ISO RGD PMID:19805173 RGD:4889400 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560
JBrowse link
G Il1b interleukin 1 beta IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat)
CTD PMID:11743230 PMID:15883752 PMID:16310260, PMID:23143013, PMID:23237935 RGD:7175553, RGD:7204425 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:18474815 PMID:19005744 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il4r interleukin 4 receptor IEP mRNA:increased expression:heart RGD PMID:10807530 RGD:4889985 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15883752 PMID:16310260 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor IEP RGD PMID:12123772 RGD:1625444 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility
no_association
ISO RGD PMID:16697311, PMID:10194421, PMID:15227729 RGD:1582296, RGD:1581029, RGD:1582294 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itga3 integrin subunit alpha 3 IEP protein:increased expression:myocardium (rat) RGD PMID:19041328 RGD:2325287 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itgb1 integrin subunit beta 1 treatment IMP RGD PMID:28367125 RGD:13602094 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb3 integrin subunit beta 3 no_association
susceptibility
ISO DNA:polymorphism:exon:
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with arteriosclerosis; DNA:polymorphism:exon
ClinVar
OMIM
CTD
PMID:2014236 PMID:7570918 PMID:8598867 PMID:8667943 PMID:8838346 PMID:9700201 PMID:10583927 PMID:10727448 PMID:11723016 PMID:17264806 PMID:25728920 PMID:25741868, PMID:9716140, PMID:10531147, PMID:20846430 RGD:5128498, RGD:5128481, RGD:5128476 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Jak2 Janus kinase 2 susceptibility IMP associated with Myocardial Reperfusion Injury RGD PMID:22749532 RGD:10403083 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 treatment IDA RGD PMID:23647964 RGD:7247426 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP mRNA:decreased expression:heart left ventricle, epicardium, endocardium (rat) RGD PMID:21683547 RGD:9831182 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kdr kinase insert domain receptor ISO RGD PMID:16698275 RGD:1581717 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kif6 kinesin family member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21943003 NCBI chr 9:13,016,973...13,311,971
Ensembl chr 9:13,030,673...13,311,924
JBrowse link
G Klf13 Kruppel-like factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr 1:124,772,596...124,803,363
Ensembl chr 1:124,772,596...124,803,363
JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12411458 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 ISO RGD PMID:17022964 RGD:1641799 NCBI chr 1:99,298,965...99,303,048
Ensembl chr 1:99,299,011...99,303,048
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lcat lecithin cholesterol acyltransferase IDA RGD PMID:16640830 RGD:1581773 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:3279722 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldlr low density lipoprotein receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lgals2 galectin 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by null
OMIM
CTD
ClinVar
PMID:15129282, PMID:15129282 RGD:1581852 NCBI chr 7:120,071,122...120,077,612
Ensembl chr 7:120,071,124...120,077,612
JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lipg lipase G, endothelial type susceptibility ISO DNA:polymorphism: :584C>T RGD PMID:17526978 RGD:1641818 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lox lysyl oxidase ISO RGD PMID:14553832 RGD:1581883 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpl lipoprotein lipase susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP: :p.D9N (rs1801177) (human) RGD PMID:18823627 RGD:2313302 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO RGD PMID:12402342 RGD:1581913 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
susceptibility
onset
ISO DNA:missense mutation:cds:p.R952Q (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by OMIM:608446
CTD
OMIM
ClinVar
PMID:17847002, PMID:18592168, PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 susceptibility ISO RGD PMID:12394648 RGD:1581922 NCBI chr14:80,911,281...80,923,290
Ensembl chr14:80,911,270...80,924,831
JBrowse link
G Lta lymphotoxin alpha no_association
susceptibility
severity
ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by null
DNA:SNP:exon:804C>A (p.T26N) (human)
OMIM
CTD
ClinVar
PMID:12426569 PMID:12746914 PMID:14681301 PMID:15129282 PMID:15266304, PMID:15175864, PMID:23398946, PMID:12426569 RGD:1581940, RGD:8548841, RGD:1580417 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP RGD PMID:20079142 RGD:11561913 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:22635076 RGD:10412335 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:15653762 RGD:1582282 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:9753871 RGD:1582468 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mdk midkine IEP RGD PMID:9568069 RGD:1582488 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mef2a myocyte enhancer factor 2a ISO RGD PMID:15811259 RGD:1580548 NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
JBrowse link
G Mef2c myocyte enhancer factor 2C treatment IMP RGD PMID:23948075 RGD:7327215 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mff mitochondrial fission factor treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867156, PMID:23867156 RGD:12879458 NCBI chr 9:88,490,280...88,518,517
Ensembl chr 9:88,493,593...88,517,827
JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:20886221 RGD:12738232 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mgp matrix Gla protein susceptibility ISO RGD PMID:11073842 RGD:1582503 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198609 NCBI chr13:101,727,434...101,770,127
Ensembl chr13:101,727,935...101,761,541
JBrowse link
G Miat myocardial infarction associated transcript susceptibility ISO ClinVar Annotator: match by null
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:17066261 NCBI chr12:50,447,251...50,461,859 JBrowse link
G Mif macrophage migration inhibitory factor ISO
IEP
protein:increased expression:plasma
mRNA, protein:increased expression:myocardium
RGD PMID:11589847, PMID:12704210 RGD:1642008, RGD:1642003 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir125b2 microRNA 125b-2 ISO CTD Direct Evidence: therapeutic CTD PMID:29122578 NCBI chr11:16,097,346...16,097,433 JBrowse link
G Mir145 microRNA 145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29956747 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:31207208 RGD:21066347 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir223 microRNA 223 IEP RNA:increased expression:heart RGD PMID:29608885 RGD:21408565 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir30a microRNA 30a treatment IDA RGD PMID:29849775 RGD:35673318 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mir423 microRNA 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24253456 NCBI chr10:63,098,366...63,098,444
Ensembl chr10:63,098,360...63,098,453
JBrowse link
G Mir761 microRNA 761 ISO CTD Direct Evidence: therapeutic CTD PMID:23867156 NCBI chr 5:128,651,867...128,651,942
Ensembl chr 5:128,651,867...128,651,942
JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO
IEP
IDA
protein:increased expression, increased activity:heart left ventricle (rat)
human gene in rat model
associated with Coronary Artery Disease; DNA:snps, haplotype:promoter:g.-519A>G, g.-340T>C (human)
RGD PMID:15009768, PMID:8531210, PMID:11179039, PMID:19797822, PMID:16210545 RGD:1582535, RGD:7207198, RGD:7207136, RGD:7207135, RGD:1582520 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:15782494 RGD:1582556 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp14 matrix metallopeptidase 14 IEP
ISO
RGD PMID:10773235, PMID:16461815 RGD:1582587, RGD:1582569 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:16310260 PMID:24358288, PMID:10773235, PMID:11179039 RGD:1582587, RGD:7207136 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:15467919 RGD:1580551 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO RGD PMID:16769909 RGD:1582373 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility ISO
IEP
IDA
protein:increased expression:coronary artery, plasma (human)
protein:increased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:heart left ventricle (rat)
DNA:snps:promoter, exon:g.-1562C>T, p.R279Q (rs3918242, rs2664538) (human)
CTD PMID:16310260 PMID:24358288, PMID:15118287, PMID:25520329, PMID:8531210, PMID:17893005, PMID:14729404, PMID:16845718 RGD:1582645, RGD:13204799, RGD:7207198, RGD:7207049, RGD:1582639, RGD:1582653 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 ISO DNA:missense mutation: :m.5178C>A (p.L237M) (human) RGD PMID:15262184 RGD:1581054 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO associated with Kidney Failure, Chronic; DNA:transition:cds:g.677C>T rs1801133 (human)
DNA:SNP: :677C>T (human)
RGD PMID:19272686, PMID:10090925 RGD:6893548, RGD:10449412 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IDA protein:decreased serine phosphorylation:heart
associated with Diabetes Mellitus, Experimental
RGD PMID:20352476, PMID:23773982 RGD:10041035, RGD:10041040 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myh6 myosin heavy chain 6 IEP RGD PMID:15090263 RGD:11565830 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 ISO
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:11743230, PMID:15090263 RGD:11565830 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO
IEP
mRNA, protein:increased expression:heart
protein:alternative form, increased expression:myocardium
RGD PMID:19853610, PMID:23462508 RGD:2325979, RGD:40924663 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr 2:119,139,717...119,153,753
Ensembl chr 2:119,139,717...119,153,753
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment IDA
ISO
RGD PMID:23290949, PMID:24915518 RGD:10412734, RGD:10412738 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:19616538 RGD:10413879 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10090345 PMID:11489778 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility
treatment
ISO
IEP
IDA
DNA:repeats:intron
protein:decreased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism
human gene in rat model
DNA:duplication:intron:IVS4?-?+27 (human)
CTD PMID:10510054 PMID:16337503, PMID:10531147, PMID:29311930, PMID:28980197, PMID:22012955, PMID:17637430, PMID:11903359, PMID:12362496 RGD:5128481, RGD:13503346, RGD:13450930, RGD:7771563, RGD:7771561, RGD:1580284, RGD:1580283 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Npm1 nucleophosmin 1 ISO protein:increased expression:cardiomyocyte: RGD PMID:21444791 RGD:11535018 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Nppa natriuretic peptide A ISO
IEP
DNA:snp:cds:c.2238T>C (human)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:9527094 PMID:11743230, PMID:12514664, PMID:16087130 RGD:1579982, RGD:1580000 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B IMP
ISO
IEP
RGD PMID:19858735, PMID:17639095, PMID:17256064 RGD:2324680, RGD:7247724, RGD:1642266 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npr1 natriuretic peptide receptor 1 susceptibility ISO DNA:missense mutation:cds:p.M341I (human) RGD PMID:14646971 RGD:1580174 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16413583 PMID:17587755 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Nrg1 neuregulin 1 treatment ISO RGD PMID:24200746 RGD:10449026 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 susceptibility ISO DNA:missense mutation:cds:p.K167N (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by null
OMIM
CTD
ClinVar
PMID:12646194 PMID:12810610 PMID:14684693, PMID:12646194 RGD:1580996 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment IEP RGD PMID:20886221 RGD:12738232 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Oprd1 opioid receptor, delta 1 IDA
IMP
RGD PMID:12798419, PMID:15076225 RGD:2316587, RGD:9831425 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oprk1 opioid receptor, kappa 1 IMP RGD PMID:15076225 RGD:9831425 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19334620 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
JBrowse link
G Pappa1 pappalysin 1 susceptibility ISO DNA:polymorphism:intron
CTD Direct Evidence: marker/mechanism
CTD PMID:11586954, PMID:17700210 RGD:1642324 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO protein:altered processing:left ventricle (mouse) RGD PMID:21282286 RGD:5684012 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 ISO DNA:SNP:intron: (rs6080699) (human) RGD PMID:20036365 RGD:6483554 NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
JBrowse link
G Pde3a phosphodiesterase 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr 4:175,431,904...175,703,844
Ensembl chr 4:175,431,904...175,700,238
JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:17339532 RGD:2314468 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pdgfd platelet derived growth factor D IEP mRNA,protein:altered expression:myocardium: RGD PMID:21767547 RGD:9854703 NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 IEP protein:decreased expression:right heart ventricle, ventricular septum RGD PMID:17089028 RGD:2302667 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 onset
no_association
ISO DNA:polymorphisms: :p.N563S, p.G670R (human)
DNA:missense mutation:cds:p.R643G (human)
DNA:missense mutations:cds:p.L125V, p.S563N (human)
RGD PMID:11795274, PMID:15488875, PMID:15265022 RGD:2311656, RGD:6771224, RGD:1581009 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pgf placental growth factor ISO
IMP
RGD PMID:20649603, PMID:21329947, PMID:22114497 RGD:6483584, RGD:6483777, RGD:6483773 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Phactr1 phosphatase and actin regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198609 PMID:26098115 NCBI chr17:23,245,423...23,761,207 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:20056919 RGD:6482688 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO protein:decreased expression:serum RGD PMID:19644070 RGD:6482786 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plat plasminogen activator, tissue type treatment ISO DNA:snp:enhancer:g.-7351C>T (human)
CTD Direct Evidence: therapeutic
CTD PMID:1430592 PMID:1492007 PMID:1898952 PMID:1899364 PMID:1900011 PMID:2104561 PMID:2105625 PMID:2494454 PMID:2505604 PMID:2521976 PMID:3089627 PMID:3121335 PMID:7488445 PMID:7723950 PMID:7775709 PMID:7902905 PMID:8328192 PMID:8554022 PMID:8598594 PMID:9183334 PMID:10171637 PMID:10505926 PMID:10645301 PMID:10914357 PMID:11382373 PMID:11489769 PMID:12074692 PMID:12227717 PMID:12848087 PMID:15215796 PMID:15301905 PMID:18195371 PMID:19341228 PMID:20122609, PMID:11848437, PMID:7994806 RGD:1580881, RGD:11541077 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase ISO
IEP
DNA:SNP:3' utr:c.*141C>T (rs4065) (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:increased expression:myocardium
CTD PMID:1908371 PMID:2174952 PMID:2382605 PMID:3068399 PMID:3984876 PMID:8416330, PMID:20518747, PMID:17653104, PMID:20952728 RGD:6484126, RGD:6484145, RGD:6484133 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO
IEP
mRNA, protein:increased expression:myocardium RGD PMID:12393744, PMID:20952728 RGD:1580897, RGD:6484133 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Plcb1 phospholipase C beta 1 IEP protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Plcb3 phospholipase C beta 3 IEP protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr 1:222,207,887...222,224,993
Ensembl chr 1:222,209,575...222,224,910
JBrowse link
G Pln phospholamban treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16026515 PMID:16162791, PMID:23781262 RGD:7327176 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Pon1 paraoxonase 1 ISO RGD PMID:10978258, PMID:10610741 RGD:1580202, RGD:1580198 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Postn periostin IEP protein:increased expression:heart: RGD PMID:24212842 RGD:10041024 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO DNA:SNP:intron:rs4253623, minor allele associated with increased risk (human) RGD PMID:18549840 RGD:5562819 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP
ISO
protein:decreased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:22503866, PMID:22503866, PMID:22087236 RGD:7242181, RGD:6484266 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: therapeutic CTD PMID:16782078 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO RGD PMID:10936861 RGD:11100014 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 susceptibility ISO ClinVar Annotator: match by null
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:16845397 PMID:19282875 NCBI chr 6:76,174,460...76,205,429
Ensembl chr 6:76,174,452...76,205,426
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:15138244 RGD:1581289 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptn pleiotrophin IEP protein:increased expression:myocardium (rat) RGD PMID:17925408 RGD:10044023 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Rad50 RAD50 double strand break repair protein treatment IDA RGD PMID:15623426 RGD:9831390 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142
JBrowse link
G Ranbp1 RAN binding protein 1 IEP protein:decreased expression:heart ventricle, cytoplasm (rat) RGD PMID:25341891 RGD:9835001 NCBI chr11:86,890,585...86,898,818
Ensembl chr11:86,890,585...86,898,818
JBrowse link
G Reg1a regenerating family member 1 alpha IEP mRNA:increased expression:heart left ventricle (rat) RGD PMID:15778284 RGD:9850130 NCBI chr 4:109,497,962...109,500,626
Ensembl chr 4:109,497,962...109,501,082
JBrowse link
G Ren renin susceptibility ISO associated with Hypertension; protein:increased activity:plasma (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:1668233, PMID:1759997 RGD:6892687 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Retn resistin ISO protein:increased expression:plasma RGD PMID:18997620 RGD:7207152 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP protein:increased threonine phosphorylation:heart left ventricle RGD PMID:16540832 RGD:1642998 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G S100b S100 calcium binding protein B IEP
ISO
mRNA, protein:increased expression:left ventricle myocardium, plasma
CTD Direct Evidence: marker/mechanism
CTD PMID:9788975, PMID:19910580 RGD:2325647 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Sdc1 syndecan 1 IEP mRNA:increased expression:myocardium RGD PMID:9237025 RGD:2311712 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016
JBrowse link
G Sdc4 syndecan 4 ISO protein:increased expression:plasma RGD PMID:11372670 RGD:2312328 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sell selectin L ISO CTD Direct Evidence: marker/mechanism CTD PMID:10070497 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P susceptibility ISO
IEP
associated with Hypertension;protein:increased expression:plasma
protein:increased expression:serum
DNA:polymorphisms, haplotypes:cds:p.S290N, p.N562D, p.T715P (human)
RGD PMID:17391113, PMID:21162967, PMID:21567088, PMID:12165563 RGD:2312304, RGD:6219003, RGD:6218991, RGD:1580075 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO
IMP
DNA:deletion:promoter:g.-676_-674delG (human) RGD PMID:12477941, PMID:16053971 RGD:1626626, RGD:8547882 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 IEP RGD PMID:19109969 RGD:4107088 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Shh sonic hedgehog signaling molecule treatment IMP RGD PMID:20052412 RGD:12879408 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Sirt1 sirtuin 1 IEP protein:altered localization:nucleus RGD PMID:20089851 RGD:2316169 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sirt3 sirtuin 3 treatment IEP RGD PMID:24471974 RGD:9586050 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Slc27a1 solute carrier family 27 member 1 IEP protein:decreased expression:infarcted heart RGD PMID:17034771 RGD:1642800 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc27a6 solute carrier family 27 member 6 IEP protein:decreased expression:heart RGD PMID:17034771 RGD:1642800 NCBI chr18:53,609,497...53,667,833
Ensembl chr18:53,609,214...53,667,970
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor treatment IEP RGD PMID:23361363 RGD:9999400 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Smad2 SMAD family member 2 treatment IEP RGD PMID:11087260 RGD:12903276 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad4 SMAD family member 4 treatment IEP RGD PMID:11087260 RGD:12903276 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEP protein:increased expression:heart RGD PMID:16377761 RGD:2298918 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO CTD Direct Evidence: therapeutic
human gene in a rat model
CTD PMID:21600015, PMID:11864929, PMID:22006090 RGD:1581222, RGD:8655953 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 IDA
ISO
IEP
CTD Direct Evidence: therapeutic CTD PMID:12160945, PMID:14575298, PMID:9250167 RGD:1581148, RGD:1580839 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324