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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Invasive Candidiasis
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Accession:DOID:9000522 term browser browse the term
Definition:An important nosocomial fungal infection with species of the genus CANDIDA, most frequently CANDIDA ALBICANS. Invasive candidiasis occurs when candidiasis goes beyond a superficial infection and manifests as CANDIDEMIA, deep tissue infection, or disseminated disease with deep organ involvement.
Synonyms:exact_synonym: Invasive Candidiases
 primary_id: MESH:D058365
 xref: EFO:1001283


show annotations for term's descendants           Sort by:
Invasive Candidiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGAM integrin subunit alpha M ISO protein: increased expression: kidney RGD PMID:21063074 RGD:7207265 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G PTX3 pentraxin 3 severity IAGP associated with hematologic cancer;DNA:SNP:intron:rs1840680 RGD PMID:30275011 RGD:38501097 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633 		JBrowse link
Candidemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule ameliorates ISO associated with endotoxemia RGD PMID:32154791 RGD:127345119 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G EPHB2 EPH receptor B2 exacerbates ISO RGD PMID:33685996 RGD:127229905 NCBI chr 1:22,710,838...22,921,500
Ensembl chr 1:22,710,839...22,921,500 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 41189
    disease by infectious agent 2738
      Bacterial Infections and Mycoses 1246
        fungal infectious disease 183
          candidiasis 89
            Invasive Candidiasis 4
              Candidemia 2
Path 2
Term Annotations click to browse term
  disease 41189
    disease by infectious agent 2738
      Bacterial Infections and Mycoses 1246
        fungal infectious disease 183
          systemic mycosis 154
            opportunistic mycosis 142
              candidiasis 89
                Invasive Candidiasis 4
                  Candidemia 2
paths to the root