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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Invasive Candidiasis
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Accession:DOID:9000522 term browser browse the term
Definition:An important nosocomial fungal infection with species of the genus CANDIDA, most frequently CANDIDA ALBICANS. Invasive candidiasis occurs when candidiasis goes beyond a superficial infection and manifests as CANDIDEMIA, deep tissue infection, or disseminated disease with deep organ involvement.
Synonyms:exact_synonym: Invasive Candidiases
 primary_id: MESH:D058365
 alt_id: RDO:0007823
For additional species annotation, visit the Alliance of Genome Resources.


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Invasive Candidiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGAM integrin subunit alpha M ISO protein: increased expression: kidney RGD PMID:21063074 RGD:7207265 NCBI chr 6:16,944,062...16,996,525
Ensembl chr 6:16,808,971...16,996,286
JBrowse link
G PTX3 pentraxin 3 severity ISO associated with hematologic cancer;DNA:SNP:intron:rs1840680 RGD PMID:30275011 RGD:38501097 NCBI chr23:50,952,835...50,958,607
Ensembl chr23:50,952,885...50,958,167
JBrowse link
Candidemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHB2 EPH receptor B2 exacerbates ISO RGD PMID:33685996 RGD:127229905 NCBI chr 2:76,427,112...76,551,494
Ensembl chr 2:76,428,203...76,612,786
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13742
    disease by infectious agent 1792
      Bacterial Infections and Mycoses 706
        fungal infectious disease 132
          candidiasis 64
            Invasive Candidiasis 3
              Candidemia 1
Path 2
Term Annotations click to browse term
  disease 13742
    disease by infectious agent 1792
      Bacterial Infections and Mycoses 706
        fungal infectious disease 132
          systemic mycosis 124
            opportunistic mycosis 114
              candidiasis 64
                Invasive Candidiasis 3
                  Candidemia 1
paths to the root