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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Invasive Candidiasis
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Accession:DOID:9000522 term browser browse the term
Definition:An important nosocomial fungal infection with species of the genus CANDIDA, most frequently CANDIDA ALBICANS. Invasive candidiasis occurs when candidiasis goes beyond a superficial infection and manifests as CANDIDEMIA, deep tissue infection, or disseminated disease with deep organ involvement.
Synonyms:exact_synonym: Invasive Candidiases
 primary_id: MESH:D058365
 alt_id: RDO:0007823
For additional species annotation, visit the Alliance of Genome Resources.


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Invasive Candidiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGAM integrin subunit alpha M ISO protein: increased expression: kidney RGD PMID:21063074 RGD:7207265 NCBI chr16:23,634,476...23,707,147
Ensembl chr16:31,630,146...31,702,406
JBrowse link
G PTX3 pentraxin 3 severity ISO associated with hematologic cancer;DNA:SNP:intron:rs1840680 RGD PMID:30275011 RGD:38501097 NCBI chr 3:154,485,470...154,492,293
Ensembl chr 3:162,537,577...162,543,652
JBrowse link
Candidemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHB2 EPH receptor B2 exacerbates ISO RGD PMID:33685996 RGD:127229905 NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13774
    disease by infectious agent 1769
      Bacterial Infections and Mycoses 702
        fungal infectious disease 127
          candidiasis 63
            Invasive Candidiasis 3
              Candidemia 1
Path 2
Term Annotations click to browse term
  disease 13774
    disease by infectious agent 1769
      Bacterial Infections and Mycoses 702
        fungal infectious disease 127
          systemic mycosis 120
            opportunistic mycosis 112
              candidiasis 63
                Invasive Candidiasis 3
                  Candidemia 1
paths to the root