RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Viral Myocarditis
Accession: DOID:9000469
browse the term
Definition: An uncommon inflammatory disorder of the myocardium caused by a virus.
Synonyms: exact_synonym: VMC
narrow_synonym: CVMC; chronic viral myocarditis
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Adar
adenosine deaminase, RNA-specific
ISO
protein:alternative form:heart (mouse) associated with Coxsackievirus Infections
RGD
PMID:30669342 PMID:27584568
RGD:125097512 , RGD:125097517
NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282
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Casp3
caspase 3
treatment
ISO
RGD
PMID:29977885 PMID:29556195 PMID:27693786 PMID:27184135 PMID:24303754 PMID:21055654 More...
RGD:13702866 , RGD:13702867 , RGD:13702870 , RGD:13702871 , RGD:13702873 , RGD:13702877
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
ISO
RGD
PMID:21055654
RGD:13702877
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Cd1d1
CD1d1 molecule
ameliorates
ISO
associated with Coxsackievirus Infections
RGD
PMID:12626572
RGD:127345102
NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
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Cd40
CD40 molecule
ISO
RGD
PMID:10440754
RGD:13702887
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd40lg
CD40 ligand
treatment
ISO IMP
RGD
PMID:19914091 PMID:11945021 PMID:9721703
RGD:13702885 , RGD:13702886 , RGD:13702888
NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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Cd55
CD55 molecule (Cromer blood group)
treatment
ISO
RGD
PMID:12533688
RGD:13702890
NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
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Cd80
Cd80 molecule
treatment
ISO
RGD
PMID:29039143
RGD:13702893
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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Cd86
CD86 molecule
treatment
ISO
RGD
PMID:10398149
RGD:13702899
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Cd8a
CD8 subunit alpha
ISO
associated with Coxsackievirus Infections;protein:increased expression:myocardium (mouse)
RGD
PMID:17113076
RGD:124715457
NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040
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F3
coagulation factor III, tissue factor
ISO
RGD
PMID:18495150
RGD:11341693
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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Icam1
intercellular adhesion molecule 1
treatment
ISO
RGD
PMID:11156888 PMID:11092674
RGD:13702912 , RGD:13702913
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Ido1
indoleamine 2,3-dioxygenase 1
ISO
RGD
PMID:31416389
RGD:39939047
NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
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Ifnb1
interferon beta 1
exacerbates
ISO
associated with Coxsackievirus Infections
RGD
PMID:15249500
RGD:401854229
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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Ifng
interferon gamma
treatment
ISO
RGD
PMID:11092674
RGD:13702913
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il17a
interleukin 17A
treatment
ISO
RGD
PMID:23702425
RGD:9227415
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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Il21
interleukin 21
treatment
ISO
RGD
PMID:25889760
RGD:127285552
NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
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Il27
interleukin 27
ameliorates
ISO
RGD
PMID:26578236
RGD:126790546
NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
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Il33
interleukin 33
treatment
ISO
RGD
PMID:28041873
RGD:40400900
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Il6
interleukin 6
severity
ISO
mRNA:increased expression:heart (mouse)
RGD
PMID:25998987
RGD:401850594
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Mir146b
microRNA 146b
ameliorates
ISO
associated with Coxsackievirus Infections
RGD
PMID:23588407
RGD:41404640
NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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Mir21
microRNA 21
ameliorates
ISO
associated with Coxsackievirus Infections
RGD
PMID:23588407 PMID:23544605
RGD:41404640 , RGD:41404700
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Nrg1
neuregulin 1
ISO
associated with Coxsackievirus Infections;protein:increased expression:heart (mouse)
RGD
PMID:31396490
RGD:39131284
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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Plau
plasminogen activator, urokinase
susceptibility
ISO
mRNA:increased expression:heart (mouse)
RGD
PMID:19246678
RGD:7241803
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Ppia
peptidylprolyl isomerase A
ameliorates
ISO
associated with Coxsackievirus Infections
RGD
PMID:22446162
RGD:150429627
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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Srebf1
sterol regulatory element binding transcription factor 1
severity
ISO
mRNA:increased expression:heart (mouse)
RGD
PMID:25998987
RGD:401850594
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srf
serum response factor
severity
ISO
mRNA:increased expression:heart (mouse)
RGD
PMID:25998987
RGD:401850594
NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
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Zc3h12a
zinc finger CCCH type containing 12A
disease_progression
ISO
associated with Coxsackievirus Infections; mRNA,protein:increased expression:heart,pancreas (mouse)
RGD
PMID:29043433
RGD:39938975
NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
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