RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Animal Mammary Neoplasms
Accession: DOID:9000403
browse the term
Definition: Tumors or cancer of the MAMMARY GLAND in animals (MAMMARY GLANDS, ANIMAL).
Synonyms: exact_synonym: animal mammary neoplasm; mammary neoplasm; mammary neoplasms
narrow_synonym: animal mammary carcinoma; animal mammary carcinomas
primary_id: MESH:D015674
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Acsl1
acyl-CoA synthetase long-chain family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
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Actb
actin, beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
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Actg1
actin, gamma, cytoplasmic 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:120,236,513...120,239,321
Ensembl chr11:120,236,516...120,239,368
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Actn4
actinin alpha 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765
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Adcy5
adenylate cyclase 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
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Alcam
activated leukocyte cell adhesion molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437
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Anxa1
annexin A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942 PMID:22248470
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
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Anxa2
annexin A2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22248470
NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077
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Anxa4
annexin A4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566
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Apc
APC, WNT signaling pathway regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9111214
NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
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Aqp1
aquaporin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
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Areg
amphiregulin
ISO
mRNA:increased expression:mammary gland
RGD
PMID:18421211
RGD:2292665
NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
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Atp5if1
ATP synthase inhibitory factor subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970
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Basp1
brain abundant, membrane attached signal protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr15:25,363,363...25,413,850
Ensembl chr15:25,363,363...25,413,850
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Brca1
breast cancer 1, early onset
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12203372
NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
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Capzb
capping actin protein of muscle Z-line subunit beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 4:138,920,210...139,019,131
Ensembl chr 4:138,920,210...139,019,129
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Cask
calcium/calmodulin dependent serine protein kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr X:13,383,319...13,713,020
Ensembl chr X:13,383,319...13,717,606
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Ccnh
cyclin H
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:85,337,504...85,361,850
Ensembl chr13:85,337,527...85,371,588
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Ccr3
C-C motif chemokine receptor 3
IEP
RGD
PMID:19787232
RGD:6893387
NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
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Cd40
CD40 antigen
treatment
IMP
RGD
PMID:15922965
RGD:8547789
NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
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Cdc42
cell division cycle 42
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 4:137,047,011...137,085,007
Ensembl chr 4:137,047,007...137,085,031
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Cdh1
cadherin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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Cdk4
cyclin dependent kinase 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:14522882
NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
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Cdkn1a
cyclin dependent kinase inhibitor 1A
onset
IMP
RGD
PMID:11103935
RGD:8662404
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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Cds1
CDP-diacylglycerol synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 5:101,913,001...101,971,724
Ensembl chr 5:101,912,996...101,971,724
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Cnn3
calponin 3, acidic
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 3:121,220,190...121,251,854
Ensembl chr 3:121,220,146...121,251,856
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Col5a1
collagen, type V, alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526
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Comt
catechol-O-methyltransferase
IEP ISO
protein:increased expression:mammary gland, cytoplasm CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18424824 PMID:6337293
RGD:2289734
NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
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Coro1a
coronin, actin binding protein 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21489049
NCBI chr 7:126,298,946...126,303,925
Ensembl chr 7:126,298,945...126,306,959
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Csn2
casein beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9879772 PMID:16316942
NCBI chr 5:87,840,478...87,847,288
Ensembl chr 5:87,840,483...87,847,489
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Csn3
casein kappa
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 5:88,073,438...88,080,409
Ensembl chr 5:88,073,438...88,080,524
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Dbi
diazepam binding inhibitor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:120,041,010...120,048,826
Ensembl chr 1:120,041,010...120,048,808
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Des
desmin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
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Dusp6
dual specificity phosphatase 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
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Eef1a1
eukaryotic translation elongation factor 1 alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 9:78,385,735...78,389,006
Ensembl chr 9:78,385,731...78,396,433
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Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743
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Egfr
epidermal growth factor receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8603490
NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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Eif5a
eukaryotic translation initiation factor 5A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:69,807,538...69,812,784
Ensembl chr11:69,807,540...69,812,784
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Eno1
enolase 1, alpha non-neuron
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
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Epcam
epithelial cell adhesion molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
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Ephx1
epoxide hydrolase 1, microsomal
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
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Erbb2
erb-b2 receptor tyrosine kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8603490
NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
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Esr1
estrogen receptor 1 (alpha)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15637090 PMID:17173897 PMID:34606849
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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Esr2
estrogen receptor 2 (beta)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15637090
NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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Ezr
ezrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
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F11r
F11 receptor
IMP
RGD
PMID:21695058
RGD:7488916
NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171
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Fabp4
fatty acid binding protein 4, adipocyte
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
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Fgf2
fibroblast growth factor 2
IMP
RGD
PMID:22407271
RGD:8554853
NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
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Fn1
fibronectin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
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Furin
furin, paired basic amino acid cleaving enzyme
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 7:80,038,942...80,055,188
Ensembl chr 7:80,038,333...80,055,184
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G0s2
G0/G1 switch gene 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
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Gata3
GATA binding protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845
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Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784
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Gda
guanine deaminase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809
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Ggt1
gamma-glutamyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
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Glycam1
glycosylation dependent cell adhesion molecule 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:103,471,186...103,473,508
Ensembl chr15:103,471,186...103,473,508
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Gm20348
predicted gene, 20348
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21489049
NCBI chr12:4,860,475...4,867,155
Ensembl chr12:4,860,494...4,867,142
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Gnai2
G protein subunit alpha i2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
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Gss
glutathione synthetase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730
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H3f3b
H3.3 histone B
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:115,912,787...115,921,313
Ensembl chr11:115,912,738...115,918,788
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Hba-a1
hemoglobin alpha, adult chain 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr11:32,233,672...32,234,486
Ensembl chr11:32,233,511...32,234,465
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Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:103,148,840...103,155,119
Ensembl chr15:103,148,859...103,155,119
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Hras
Harvey rat sarcoma virus oncogene
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8185828
NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
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Id3
inhibitor of DNA binding 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
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Id4
inhibitor of DNA binding 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14633621
NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502
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Igf2
insulin-like growth factor 2
ISO
mRNA:increased expression:mammary gland
RGD
PMID:18421211
RGD:2292665
NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553
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Il6st
interleukin 6 signal transducer
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
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Ins1
insulin I
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:21558470
NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
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Insig1
insulin induced gene 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
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Kdr
kinase insert domain protein receptor
IMP
RGD
PMID:19888452
RGD:5684399
NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
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Kitl
kit ligand
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
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Kng1
kininogen 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22248470
NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
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Krt5
keratin 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr15:101,615,504...101,621,340
Ensembl chr15:101,615,505...101,621,333
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Krt71
keratin 71
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:101,642,384...101,651,532
Ensembl chr15:101,642,384...101,651,544
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Lgals7
lectin, galactose binding, soluble 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:28,563,258...28,565,711
Ensembl chr 7:28,563,278...28,565,709
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Lin7a
lin-7 homolog A, crumbs cell polarity complex component
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:107,107,410...107,261,007
Ensembl chr10:107,107,547...107,257,335
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Lpl
lipoprotein lipase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
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Lsr
lipolysis stimulated lipoprotein receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 7:30,657,195...30,672,894
Ensembl chr 7:30,657,195...30,672,889
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Map2k6
mitogen-activated protein kinase kinase 6
IGI
RGD
PMID:17016428
RGD:7495832
NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
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Mdh2
malate dehydrogenase 2, NAD (mitochondrial)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
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Mgp
matrix Gla protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821
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Mif
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
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Mir100
microRNA 100
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24447120
NCBI chr 9:41,442,721...41,442,800
Ensembl chr 9:41,442,721...41,442,800
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Mir10a
microRNA 10a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24447120
NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100
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Mir10b
microRNA 10b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24447120
NCBI chr 2:74,556,414...74,556,481
Ensembl chr 2:74,556,414...74,556,481
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Mir145a
microRNA 145a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24447120
NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965
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Mir199a-2
microRNA 199a-2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24447120
NCBI chr 1:162,045,383...162,045,492
Ensembl chr 1:162,045,383...162,045,492
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Mir205
microRNA 205
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24447120
NCBI chr 1:193,189,771...193,189,838
Ensembl chr 1:193,189,771...193,189,838
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Mmp9
matrix metallopeptidase 9
treatment
IEP
RGD
PMID:23714264
RGD:8547831
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Mpzl1
myelin protein zero-like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 1:165,419,745...165,462,144
Ensembl chr 1:165,419,809...165,462,107
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Mrc2
mannose receptor, C type 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:105,183,440...105,241,971
Ensembl chr11:105,183,469...105,241,965
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mt-Co1
cytochrome c oxidase I, mitochondrial
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
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Ndn
necdin, MAGE family member
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21489049
NCBI chr 7:61,998,025...61,999,676
Ensembl chr 7:61,996,317...62,000,010
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Notch4
notch 4
IAGP
DNA, mRNA:mutation, alternative form
RGD
PMID:8030284
RGD:2299155
NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477
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Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 2:24,944,370...24,952,893
Ensembl chr 2:24,944,367...24,952,893
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Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
ameliorates
IMP
RGD
PMID:20802235
RGD:150520014
NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760
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Pdgfa
platelet derived growth factor, alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
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Pebp1
phosphatidylethanolamine binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
G
Pgam1
phosphoglycerate mutase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099
G
Pgr
progesterone receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15637090
NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
G
Phb1
prohibitin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
G
Pkm
pyruvate kinase, muscle
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
G
Plk2
polo like kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378
G
Ppara
peroxisome proliferator activated receptor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11137312
NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
G
Prdx2
peroxiredoxin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
G
Prl
prolactin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:6280079 PMID:16316942
NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
G
Prlr
prolactin receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942 PMID:17173897
NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266
G
Psma4
proteasome subunit alpha 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 9:54,858,074...54,865,316
Ensembl chr 9:54,858,074...54,865,314
G
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr14:55,815,951...55,818,984
Ensembl chr14:55,815,580...55,818,986
G
Ptbp1
polypyrimidine tract binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:79,690,502...79,700,269
Ensembl chr10:79,690,261...79,700,605
G
Ptger1
prostaglandin E receptor 1 (subtype EP1)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11751431
NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382
G
Ptn
pleiotrophin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155
G
Ran
RAN, member RAS oncogene family
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387
G
Rasa1
RAS p21 protein activator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249
G
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:92,028,526...92,268,584
Ensembl chr13:92,028,519...92,268,164
G
Rassf1
Ras association (RalGDS/AF-6) domain family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20008439
NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466
G
Rb1
RB transcriptional corepressor 1
IMP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:14522882 PMID:21364977
RGD:8547983
NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
G
Rbp1
retinol binding protein 1, cellular
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628
G
Rbp4
retinol binding protein 4, plasma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729
G
Rcn1
reticulocalbin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 2:105,216,293...105,229,664
Ensembl chr 2:105,216,636...105,229,664
G
Rel
reticuloendotheliosis oncogene
IMP
DNA:transgene:mammary gland:mouse c-Rel cDNA driven by the MMTV-LTR promoter
RGD
PMID:12897145
RGD:2300264
NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
G
Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
IEP
RGD
PMID:12897145
RGD:2300264
NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
G
Rpl3
ribosomal protein L3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:79,961,993...79,967,553
Ensembl chr15:79,961,992...79,976,069
G
Rpl6
ribosomal protein L6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:121,342,564...121,347,304
Ensembl chr 5:121,342,544...121,347,304
G
Rps14
ribosomal protein S14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr18:60,907,668...60,911,618
Ensembl chr18:60,880,170...60,911,618
G
S100a6
S100 calcium binding protein A6 (calcyclin)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488
G
S100a8
S100 calcium binding protein A8 (calgranulin A)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22248470
NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
G
S1pr1
sphingosine-1-phosphate receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721
G
Scarb1
scavenger receptor class B, member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158
G
Scd2
stearoyl-Coenzyme A desaturase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
G
Selenop
selenoprotein P
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
G
Sgk1
serum/glucocorticoid regulated kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
G
Slc12a2
solute carrier family 12, member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr18:58,011,505...58,079,893
Ensembl chr18:58,011,750...58,079,893
G
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr11:120,382,663...120,391,987
Ensembl chr11:120,382,666...120,390,013
G
Sncg
synuclein, gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746
G
Snrpd3
small nuclear ribonucleoprotein D3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:75,353,852...75,371,300
Ensembl chr10:75,353,385...75,373,215
G
Sod1
superoxide dismutase 1, soluble
ISO
protein:decreased expression:mammary gland (rat)
RGD
PMID:17157473
RGD:8657018
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
G
Sox9
SRY (sex determining region Y)-box 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
G
Spint2
serine protease inhibitor, Kunitz type 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:28,955,755...28,981,484
Ensembl chr 7:28,955,748...28,981,337
G
Srsf2
serine and arginine-rich splicing factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920
G
Stat3
signal transducer and activator of transcription 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
G
Stat5a
signal transducer and activator of transcription 5A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:15609129 PMID:16316942 PMID:17173897 PMID:20235097
NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
G
Stmn1
stathmin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154
G
Tgfa
transforming growth factor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8603490
NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
G
Thrsp
thyroid hormone responsive
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
G
Tkt
transketolase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr14:30,271,088...30,296,681
Ensembl chr14:30,270,316...30,296,677
G
Tle4
transducin-like enhancer of split 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr19:14,425,434...14,575,542
Ensembl chr19:14,425,514...14,575,415
G
Tmem37
transmembrane protein 37
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21489049
NCBI chr 1:119,995,106...120,001,799
Ensembl chr 1:119,995,107...120,001,804
G
Tpm3
tropomyosin 3, gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 3:89,979,958...90,008,209
Ensembl chr 3:89,979,956...90,008,209
G
Trf
transferrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9879772 PMID:16316942
NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
G
Trps1
transcriptional repressor GATA binding 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:50,518,149...50,754,027
Ensembl chr15:50,518,148...50,753,859
G
Tsc22d1
TSC22 domain family, member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
G
Tubb2b
tubulin, beta 2B class IIB
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr13:34,310,991...34,314,337
Ensembl chr13:34,310,731...34,314,449
G
Ube2i
ubiquitin-conjugating enzyme E2I
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr17:25,479,484...25,494,965
Ensembl chr17:25,479,482...25,493,856
G
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
G
Vamp8
vesicle-associated membrane protein 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686
G
Wap
whey acidic protein
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:6,585,483...6,588,654
Ensembl chr11:6,585,482...6,588,637
G
Wnt1
wingless-type MMTV integration site family, member 1
IEP
mRNA:increased expression:tumors:insertion of MMTV into Wnt1 gene increases expression and decreases latency of tumorigenesis in WAP-TGFalpha mice
RGD
PMID:10918574
RGD:2298804
NCBI chr15:98,687,738...98,691,711
Ensembl chr15:98,687,738...98,691,718
G
Wnt3
wingless-type MMTV integration site family, member 3
IEP
mRNA:increased expression:tumors:insertion of MMTV into Wnt3 gene increases expression and decreases latency of tumorigenesis in WAP-TGFalpha mice
RGD
PMID:10918574
RGD:2298804
NCBI chr11:103,665,000...103,708,854
Ensembl chr11:103,664,976...103,708,783
G
Wnt6
wingless-type MMTV integration site family, member 6
IEP
Adenomyoepithelioma; mRNA:increased expression:tumor:PLAG-1 transgenic mice
RGD
PMID:18649356
RGD:2298845
NCBI chr 1:74,793,499...74,824,481
Ensembl chr 1:74,811,051...74,824,481
G
Xdh
xanthine dehydrogenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
G
Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173
G
Abcb1a
ATP-binding cassette, sub-family B member 1A
IEP
RGD
PMID:19654309
RGD:2315553
NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
G
Abcb1b
ATP-binding cassette, sub-family B member 1B
IEP EXP
CTD Direct Evidence: therapeutic
CTD RGD
PMID:14633655 PMID:19654309
RGD:2315553
NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
G
Abcg2
ATP binding cassette subfamily G member 2 (Junior blood group)
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:22767648
NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
G
Acsl1
acyl-CoA synthetase long-chain family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
G
Actb
actin, beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509
G
Actg1
actin, gamma, cytoplasmic 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:120,236,513...120,239,321
Ensembl chr11:120,236,516...120,239,368
G
Actn4
actinin alpha 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765
G
Adcy5
adenylate cyclase 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
G
Adipoq
adiponectin, C1Q and collagen domain containing
disease_progression treatment
IMP ISO
RGD
PMID:19447866 PMID:22246620
RGD:8694414 , RGD:8694468
NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
G
Afp
alpha fetoprotein
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16322315
NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
G
Agt
angiotensinogen
treatment
IDA
RGD
PMID:20837666
RGD:5129167
NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
G
Agtr1a
angiotensin II receptor, type 1a
ISO EXP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:8389152 PMID:18421211
RGD:2292665
NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
G
Agtr2
angiotensin II receptor, type 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8389152
NCBI chr X:21,350,863...21,355,072
Ensembl chr X:21,350,783...21,355,403
G
Akt1
thymoma viral proto-oncogene 1
IAGP
RGD
PMID:17210696
RGD:2315600
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
G
Akt2
thymoma viral proto-oncogene 2
IAGP
RGD
PMID:17210696
RGD:2315600
NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
G
Alcam
activated leukocyte cell adhesion molecule
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat)
CTD RGD
PMID:16316942 PMID:16316942
RGD:2306898
NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437
G
Alox5ap
arachidonate 5-lipoxygenase activating protein
ISO
mRNA:increased expression:mammary gland tumor (rat)
RGD
PMID:18959458
RGD:2313895
NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
G
Antxr1
anthrax toxin receptor 1
disease_progression
ISO
RGD
PMID:22085271
RGD:9684855
NCBI chr 6:87,110,835...87,312,757
Ensembl chr 6:87,110,835...87,312,803
G
Anxa1
annexin A1
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12376462 PMID:16316942 PMID:16316942
RGD:2306898
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
G
Anxa4
annexin A4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566
G
Apaf1
apoptotic peptidase activating factor 1
ISO
RGD
PMID:14973070
RGD:2325748
NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
G
Apoe
apolipoprotein E
IMP
RGD
PMID:22469977
RGD:7771597
NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
G
Aqp1
aquaporin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
G
Ar
androgen receptor
ISO
RGD
PMID:12150826
RGD:6482679
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
G
Areg
amphiregulin
IEP ISO
protein:increased expression:mammary gland mRNA:increased expression:mammary gland
RGD
PMID:10225449 PMID:18421211
RGD:2292663 , RGD:2292665
NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
G
Arhgap5
Rho GTPase activating protein 5
disease_progression
ISO IMP
mRNA:increased expression:mammary gland
RGD
PMID:10939588 PMID:19703301
RGD:2316183 , RGD:126848766
NCBI chr12:52,550,555...52,618,761
Ensembl chr12:52,550,755...52,618,758
G
Atp5if1
ATP synthase inhibitory factor subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970
G
Bad
BCL2-associated agonist of cell death
treatment severity
ISO
RGD
PMID:23404339 PMID:20732338
RGD:10053670 , RGD:10053708
NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
G
Bak1
BCL2-antagonist/killer 1
IMP
RGD
PMID:19222350
RGD:2315700
NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
G
Bard1
BRCA1 associated RING domain 1
IMP
RGD
PMID:18443292
RGD:2293149
NCBI chr 1:71,066,694...71,142,300
Ensembl chr 1:71,066,657...71,142,305
G
Basp1
brain abundant, membrane attached signal protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr15:25,363,363...25,413,850
Ensembl chr15:25,363,363...25,413,850
G
Bax
BCL2-associated X protein
treatment severity
ISO
RGD
PMID:23404339 PMID:20732338
RGD:10053670 , RGD:10053708
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
G
Bcl2
B cell leukemia/lymphoma 2
treatment
ISO
RGD
PMID:23404339 PMID:22668016
RGD:10053670 , RGD:10054128
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
G
Bcl2l1
BCL2-like 1
treatment
ISO
RGD
PMID:23404339
RGD:10053670
NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
G
Bgn
biglycan
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35234341
NCBI chr X:72,527,207...72,539,542
Ensembl chr X:72,527,208...72,539,539
G
Brca1
breast cancer 1, early onset
susceptibility
ISO IAGP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12203372 PMID:22767648 PMID:12203372 PMID:17505536 PMID:18443292
RGD:1599502 , RGD:2293155 , RGD:2293149
NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
G
Bst2
bone marrow stromal cell antigen 2
disease_progression
IEP IMP
RGD
PMID:23806386 PMID:23806386
RGD:14398495 , RGD:14398495
NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100
G
Cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
disease_progression
ISO
protein:increased expression:mammary gland
RGD
PMID:6030068
RGD:2303540
NCBI chr 5:31,211,964...31,235,823
Ensembl chr 5:31,212,124...31,235,823
G
Capzb
capping actin protein of muscle Z-line subunit beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 4:138,920,210...139,019,131
Ensembl chr 4:138,920,210...139,019,129
G
Car9
carbonic anhydrase 9
ISO
RGD
PMID:17280655
RGD:2293194
NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729
G
Cask
calcium/calmodulin dependent serine protein kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr X:13,383,319...13,713,020
Ensembl chr X:13,383,319...13,717,606
G
Casp1
caspase 1
treatment
IMP
RGD
PMID:10557324
RGD:2315886
NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
G
Casp3
caspase 3
treatment severity
ISO
RGD
PMID:23404339 PMID:20732338 PMID:26699876
RGD:10053670 , RGD:10053708 , RGD:13782283
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
G
Casp7
caspase 7
treatment
ISO
RGD
PMID:23404339 PMID:23979166 PMID:26699876
RGD:10053670 , RGD:13209143 , RGD:13782283
NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
G
Casp8
caspase 8
severity
ISO
RGD
PMID:20732338
RGD:10053708
NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
G
Casp9
caspase 9
severity treatment
ISO IDA
RGD
PMID:17297389 PMID:20012353 PMID:20732338 PMID:26699876
RGD:2315933 , RGD:2315928 , RGD:10053708 , RGD:13782283
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
G
Cav1
caveolin 1, caveolae protein
onset treatment
IAGP IEP ISO
protein:decreased expression:mammary gland
RGD
PMID:15355971 PMID:9685399 PMID:15334058
RGD:2289106 , RGD:2289100 , RGD:8661780
NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
G
Ccna2
cyclin A2
IEP
protein:increased expression:mammary gland
RGD
PMID:10713672
RGD:2293347
NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
G
Ccnb1
cyclin B1
IEP
RGD
PMID:11146550
RGD:2315939
NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
G
Ccnd1
cyclin D1
IMP ISO
protein:decreased expression:mammary gland mRNA:increased expression:mammary gland (rat) mRNA, protein:increased expression:mammary gland (rat)
RGD
PMID:17440082 PMID:12602925 PMID:12649181 PMID:16316942 PMID:12376462
RGD:2296037 , RGD:2289337 , RGD:2289336 , RGD:2306898 , RGD:2292404
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
G
Ccnd3
cyclin D3
ISO IMP
mRNA, protein:increased expression:mammary gland
RGD
PMID:16311245 PMID:12853979
RGD:2316020 , RGD:2316015
NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
G
Ccne1
cyclin E1
ISO
protein:decreased expression:mammary gland
RGD
PMID:12649181 PMID:12602925
RGD:2289336 , RGD:2289337
NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
G
Ccnh
cyclin H
ISO
mRNA:increased expression:mammary gland CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12606953 PMID:12606953
RGD:9590264
NCBI chr13:85,337,504...85,361,850
Ensembl chr13:85,337,527...85,371,588
G
Ccr3
C-C motif chemokine receptor 3
IEP
RGD
PMID:21621198
RGD:6893427
NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
G
Ccr5
C-C motif chemokine receptor 5
ISO
RGD
PMID:14597737 PMID:22637726
RGD:8551810 , RGD:8551813
NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
G
Cd274
CD274 antigen
treatment
ISO
RGD
PMID:29043842
RGD:40886270
NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
G
Cd40
CD40 antigen
IEP
RGD
PMID:21137078
RGD:8547744
NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
G
Cd44
CD44 antigen
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21283680
NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
G
Cdc25a
cell division cycle 25A
ISO IMP
RGD
PMID:17283130 PMID:17638870 PMID:16951165
RGD:2764000 , RGD:2754551 , RGD:2771824
NCBI chr 9:109,704,545...109,722,963
Ensembl chr 9:109,704,647...109,722,963
G
Cdc42
cell division cycle 42
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 4:137,047,011...137,085,007
Ensembl chr 4:137,047,007...137,085,031
G
Cdh1
cadherin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
G
Cdh13
cadherin 13
severity
IAGP
RGD
PMID:18316604
RGD:2293540
NCBI chr 8:119,010,150...120,051,668
Ensembl chr 8:119,010,472...120,051,660
G
Cdk2
cyclin dependent kinase 2
IEP
RGD
PMID:16924466
RGD:2293558
NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
G
Cdk4
cyclin dependent kinase 4
susceptibility
ISO IAGP
protein:increased expression:mammary gland CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12376462 PMID:14522882 PMID:25221644 PMID:14522882 PMID:16413469
RGD:2293581 , RGD:2293577
NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
G
Cdk6
cyclin dependent kinase 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25221644
NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008
G
Cdkl2
cyclin dependent kinase like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25333262
NCBI chr 5:92,153,933...92,198,479
Ensembl chr 5:92,153,933...92,191,742
G
Cdkn1b
cyclin dependent kinase inhibitor 1B
treatment
ISO
protein:increased expression:mammary gland
RGD
PMID:15844214 PMID:22651929
RGD:2293626 , RGD:10045559
NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
G
Cdkn2a
cyclin dependent kinase inhibitor 2A
disease_progression
IAGP ISO
RGD
PMID:18060046 PMID:20681787
RGD:2289674 , RGD:8552689
NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
G
Cds1
CDP-diacylglycerol synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 5:101,913,001...101,971,724
Ensembl chr 5:101,912,996...101,971,724
G
Clu
clusterin
disease_progression
ISO
RGD
PMID:23099883
RGD:8699504
NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
G
Cnn3
calponin 3, acidic
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 3:121,220,190...121,251,854
Ensembl chr 3:121,220,146...121,251,856
G
Col18a1
collagen, type XVIII, alpha 1
severity
ISO
RGD
PMID:10766159
RGD:70690
NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382
G
Col5a1
collagen, type V, alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526
G
Csf1
colony stimulating factor 1 (macrophage)
ISO
RGD
PMID:15205327
RGD:2293710
NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
G
Csn2
casein beta
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat)
CTD RGD
PMID:9879772 PMID:16316942 PMID:16316942
RGD:2306898
NCBI chr 5:87,840,478...87,847,288
Ensembl chr 5:87,840,483...87,847,489
G
Csn3
casein kappa
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat)
CTD RGD
PMID:16316942 PMID:16316942
RGD:2306898
NCBI chr 5:88,073,438...88,080,409
Ensembl chr 5:88,073,438...88,080,524
G
Csnk2a1
casein kinase 2, alpha 1 polypeptide
ISO IMP
RGD
PMID:11827167 PMID:11827167
RGD:727632 , RGD:727632
NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772
G
Ctnnb1
catenin beta 1
IAGP IEP
DNA:missense mutations: :p.S33Y, p.S45F protein:increased expression:mammary gland
RGD
PMID:18060046 PMID:17510243
RGD:2289674 , RGD:2289816
NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
G
Dbi
diazepam binding inhibitor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:120,041,010...120,048,826
Ensembl chr 1:120,041,010...120,048,808
G
Ddr1
discoidin domain receptor family, member 1
ISO IMP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:21283680 PMID:29298894
RGD:151347446
NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
G
Des
desmin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
G
Dio1
deiodinase, iodothyronine, type I
ISO
RGD
PMID:11765219
RGD:727335
NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
G
Dnmt3b
DNA methyltransferase 3B
treatment
ISO
RGD
PMID:24447120
RGD:9588304
NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
G
Dusp1
dual specificity phosphatase 1
treatment
ISO
RGD
PMID:20837666
RGD:5129167
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
G
Dusp6
dual specificity phosphatase 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
G
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 9:78,385,735...78,389,006
Ensembl chr 9:78,385,731...78,396,433
G
Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743
G
Egfr
epidermal growth factor receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:2523869 PMID:8603490 PMID:17203220
RGD:2289979
NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
G
Eif5a
eukaryotic translation initiation factor 5A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:69,807,538...69,812,784
Ensembl chr11:69,807,540...69,812,784
G
Eno1
enolase 1, alpha non-neuron
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
G
Epcam
epithelial cell adhesion molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
G
Ephx1
epoxide hydrolase 1, microsomal
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
G
Epo
erythropoietin
treatment
ISO
RGD
PMID:12118093
RGD:11041669
NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
G
Epor
erythropoietin receptor
treatment
ISO
RGD
PMID:12118093
RGD:11041669
NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802
G
Erbb2
erb-b2 receptor tyrosine kinase 2
ISO
CTD Direct Evidence: marker/mechanism Androgen-dependent
CTD RGD
PMID:8603490 PMID:25221644 PMID:17203220 PMID:1913683 PMID:12150826
RGD:2289979 , RGD:2289920 , RGD:6482679
NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
G
Erbb3
erb-b2 receptor tyrosine kinase 3
ISO
RGD
PMID:17203220
RGD:2289979
NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
G
Erbb4
erb-b2 receptor tyrosine kinase 4
ISO
RGD
PMID:17203220
RGD:2289979
NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
G
Esr1
estrogen receptor 1 (alpha)
susceptibility
IAGP ISO IMP
protein:increased expression:epithelial cell, nucleus CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15637090 PMID:18055862 PMID:15637090 PMID:11759285
RGD:2290019 , RGD:8552983 , RGD:8553057
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
G
Esr2
estrogen receptor 2 (beta)
treatment
ISO
protein:increased expression:epithelial cell, nucleus CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15637090 PMID:24078029 PMID:15637090
RGD:7364911 , RGD:8552983
NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
G
Ezr
ezrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
G
F11r
F11 receptor
ISO
RGD
PMID:22120722
RGD:7488922
NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171
G
Fabp4
fatty acid binding protein 4, adipocyte
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
G
Fas
Fas cell surface death receptor
IMP
RGD
PMID:18094967
RGD:2290047
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
G
Fbxo10
F-box protein 10
ISO
RGD
PMID:17404222
RGD:1601189
NCBI chr 4:45,034,248...45,084,555
Ensembl chr 4:45,034,247...45,084,604
G
Fgf10
fibroblast growth factor 10
ISO
mRNA:increased expression:mammary gland
RGD
PMID:18421211
RGD:2292665
NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651
G
Fgf7
fibroblast growth factor 7
IMP
RGD
PMID:9000125
RGD:2301094
NCBI chr 2:125,876,578...125,933,105
Ensembl chr 2:125,876,578...125,933,105
G
Fgf8
fibroblast growth factor 8
IMP
RGD
PMID:9840935
RGD:2301098
NCBI chr19:45,724,930...45,731,380
Ensembl chr19:45,725,237...45,731,354
G
Flt3
FMS-like tyrosine kinase 3
IMP
RGD
PMID:10498246
RGD:2302211
NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
G
Fn1
fibronectin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
G
Frmpd1
FERM and PDZ domain containing 1
ISO
RGD
PMID:17404222
RGD:1601189
NCBI chr 4:45,183,958...45,285,936
Ensembl chr 4:45,184,875...45,285,936
G
Furin
furin, paired basic amino acid cleaving enzyme
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 7:80,038,942...80,055,188
Ensembl chr 7:80,038,333...80,055,184
G
G0s2
G0/G1 switch gene 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
G
Gata3
GATA binding protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845
G
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 2:122,424,954...122,441,758
Ensembl chr 2:122,424,948...122,441,784
G
Gda
guanine deaminase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809
G
Ggt1
gamma-glutamyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
G
Gh
growth hormone
treatment
ISO EXP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12082019 PMID:15528971 PMID:17584969 PMID:17584969 PMID:6139974
RGD:2315650 , RGD:11352806
NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
G
Glycam1
glycosylation dependent cell adhesion molecule 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:103,471,186...103,473,508
Ensembl chr15:103,471,186...103,473,508
G
Gnai2
G protein subunit alpha i2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
G
Gsk3b
glycogen synthase kinase 3 beta
treatment
ISO
RGD
PMID:28810530
RGD:13792729
NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
G
Gsn
gelsolin
ISO
mRNA:decreased expression
RGD
PMID:8895730
RGD:1599869
NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904
G
Gss
glutathione synthetase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730
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H19
H19, imprinted maternally expressed transcript
ISO
RGD
PMID:15170812
RGD:1642758
NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,131,917
G
H2ax
H2A.X variant histone
treatment
IDA
RGD
PMID:22384017
RGD:7240549
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
G
H3f3b
H3.3 histone B
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:115,912,787...115,921,313
Ensembl chr11:115,912,738...115,918,788
G
Hba-a1
hemoglobin alpha, adult chain 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr11:32,233,672...32,234,486
Ensembl chr11:32,233,511...32,234,465
G
Hif1a
hypoxia inducible factor 1, alpha subunit
treatment
ISO
RGD
PMID:17280655
RGD:2293194
NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
G
Hmox1
heme oxygenase 1
treatment
ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:16319139 PMID:23215791
RGD:10755708
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
G
Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:103,148,840...103,155,119
Ensembl chr15:103,148,859...103,155,119
G
Hnrnpab
heterogeneous nuclear ribonucleoprotein A/B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15538050
NCBI chr11:51,490,927...51,497,708
Ensembl chr11:51,490,927...51,497,674
G
Hp
haptoglobin
treatment
ISO
RGD
PMID:23880232
RGD:11041861
NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
G
Hras
Harvey rat sarcoma virus oncogene
ISO
DNA:mutation: :p.G12E (rat) CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:8185828 PMID:11376698 PMID:19652463
RGD:2314834
NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
G
Id1
inhibitor of DNA binding 1, HLH protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21283680
NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
G
Id3
inhibitor of DNA binding 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
G
Id4
inhibitor of DNA binding 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14633621
NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502
G
Igf1
insulin-like growth factor 1
IDA ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15217511 PMID:15528971 PMID:17584969 PMID:23342276
RGD:8549490
NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
G
Il10
interleukin 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14999141
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
G
Il18bp
interleukin 18 binding protein
ISO
mRNA:increased expression:mammary gland
RGD
PMID:18959458
RGD:2313895
NCBI chr 7:101,664,281...101,669,699
Ensembl chr 7:101,664,092...101,667,897
G
Il1rn
interleukin 1 receptor antagonist
treatment
ISO
human protein in a mouse model
RGD
PMID:21890879
RGD:6771361
NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
G
Il6st
interleukin 6 signal transducer
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
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Ilk
integrin linked kinase
ISO
late onset development of tumors in transgenic mice overexpressing human ILK in mammary glands
RGD
PMID:11704830
RGD:2301733
NCBI chr 7:105,385,797...105,392,132
Ensembl chr 7:105,385,799...105,392,132
G
Insig1
insulin induced gene 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
G
Itgb3
integrin beta 3
ISO
protein:increased expression:mammary gland:
RGD
PMID:22022542
RGD:8693386
NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
G
Kdr
kinase insert domain protein receptor
ISO
RGD
PMID:15170218 PMID:19888452
RGD:2291936 , RGD:5684399
NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
G
Kit
KIT proto-oncogene receptor tyrosine kinase
ISO
DNA:mutation (rat)
RGD
PMID:18445266
RGD:2302172
NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
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Kitl
kit ligand
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
G
Krt5
keratin 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr15:101,615,504...101,621,340
Ensembl chr15:101,615,505...101,621,333
G
Krt7
keratin 7
ISO
RGD
PMID:8570173
RGD:2317439
NCBI chr15:101,310,284...101,325,687
Ensembl chr15:101,308,924...101,328,194
G
Krt71
keratin 71
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:101,642,384...101,651,532
Ensembl chr15:101,642,384...101,651,544
G
Lep
leptin
treatment
ISO
RGD
PMID:22246620
RGD:8694468
NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
G
Lgals7
lectin, galactose binding, soluble 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:28,563,258...28,565,711
Ensembl chr 7:28,563,278...28,565,709
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISO
mRNA:splice variant (rat)
RGD
PMID:15044717
RGD:2302177
NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418
G
Lin7a
lin-7 homolog A, crumbs cell polarity complex component
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:107,107,410...107,261,007
Ensembl chr10:107,107,547...107,257,335
G
Lnpep
leucyl/cystinyl aminopeptidase
ISO
protein:increased expression:serum CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16619500 PMID:16619500
RGD:1582109
NCBI chr17:17,747,985...17,846,303
Ensembl chr17:17,741,672...17,845,312
G
Lpl
lipoprotein lipase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
G
Lsr
lipolysis stimulated lipoprotein receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 7:30,657,195...30,672,894
Ensembl chr 7:30,657,195...30,672,889
G
Map2k3
mitogen-activated protein kinase kinase 3
ISO
RGD
PMID:24233520
RGD:7495808
NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
G
Map2k7
mitogen-activated protein kinase kinase 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21317887
NCBI chr 8:4,288,740...4,297,897
Ensembl chr 8:4,288,740...4,297,897 Ensembl chr 8:4,288,740...4,297,897
G
Mapk1
mitogen-activated protein kinase 1
treatment
ISO
RGD
PMID:29435821
RGD:13800872
NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
G
Mapk3
mitogen-activated protein kinase 3
treatment
ISO
RGD
PMID:29435821
RGD:13800872
NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
G
Mdh2
malate dehydrogenase 2, NAD (mitochondrial)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252
G
Mgp
matrix Gla protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821
G
Mif
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
G
Mir155
microRNA 155
ISO
RGD
PMID:20354188 PMID:29643534
RGD:21079418 , RGD:21403681
NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092
G
Mmp13
matrix metallopeptidase 13
severity
IEP
RGD
PMID:18698413
RGD:2306081
NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
G
Mmp15
matrix metallopeptidase 15
IEP
mRNA:increased expression:mammary gland
RGD
PMID:15895410
RGD:2314949
NCBI chr 8:96,078,924...96,100,921
Ensembl chr 8:96,078,896...96,101,708
G
Mmp1a
matrix metallopeptidase 1a (interstitial collagenase)
treatment
ISO
RGD
PMID:19622769
RGD:8549722
NCBI chr 9:7,464,141...7,476,870
Ensembl chr 9:7,464,141...7,476,857
G
Mmp1b
matrix metallopeptidase 1b (interstitial collagenase)
treatment
ISO
RGD
PMID:19622769
RGD:8549722
NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
G
Mmp2
matrix metallopeptidase 2
treatment
ISO IDA
protein:increased expression:mammary gland CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:28574600 PMID:19725228 PMID:23359979
RGD:2325823 , RGD:8657038
NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
G
Mmp3
matrix metallopeptidase 3
ISO
RGD
PMID:10428026
RGD:8662909
NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
G
Mmp7
matrix metallopeptidase 7
onset
IMP
RGD
PMID:9850086
RGD:9685350
NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,587
G
Mmp9
matrix metallopeptidase 9
treatment
ISO IEP
mRNA, protein:increased expression:mammary gland CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:21283680 PMID:19725228 PMID:23359979
RGD:2325823 , RGD:8657038
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
G
Mpzl1
myelin protein zero-like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 1:165,419,745...165,462,144
Ensembl chr 1:165,419,809...165,462,107
G
Mrc2
mannose receptor, C type 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:105,183,440...105,241,971
Ensembl chr11:105,183,469...105,241,965
G
mt-Co1
cytochrome c oxidase I, mitochondrial
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
G
Mtor
mechanistic target of rapamycin kinase
ISO
RGD
PMID:22349822
RGD:10040957
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
G
Muc1
mucin 1, transmembrane
treatment
ISO
RGD
PMID:23015160
RGD:7349374
NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688
G
Myc
myelocytomatosis oncogene
treatment
IEP
RGD
PMID:22384017
RGD:7240549
NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
G
Ncoa1
nuclear receptor coactivator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21080969
NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
G
Nfe2l2
nuclear factor, erythroid derived 2, like 2
treatment
ISO
RGD
PMID:22072621
RGD:10412719
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
G
Notch4
notch 4
ISO
RGD
PMID:15531924
RGD:2299154
NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477
G
Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 2:24,944,370...24,952,893
Ensembl chr 2:24,944,367...24,952,893
G
Nudt1
nudix hydrolase 1
ISO
mRNA:increased expression:mammary gland
RGD
PMID:12036445
RGD:724605
NCBI chr 5:140,307,375...140,323,892
Ensembl chr 5:140,307,411...140,323,892
G
Oxt
oxytocin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:8647655 PMID:15089975
NCBI chr 2:130,416,432...130,418,974
Ensembl chr 2:130,418,093...130,418,974
G
Pak4
p21 (RAC1) activated kinase 4
ISO
RGD
PMID:20697354
RGD:7775027
NCBI chr 7:28,258,244...28,297,609
Ensembl chr 7:28,258,244...28,297,610
G
Parp1
poly (ADP-ribose) polymerase family, member 1
treatment
ISO
RGD
PMID:23404339
RGD:10053670
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
G
Pcna
proliferating cell nuclear antigen
ISO
mRNA,protein:increased expression:mammary gland:
RGD
PMID:2567593
RGD:10448972
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
G
Pcp4
Purkinje cell protein 4
ISO
mRNA,protein:increased expression:cytoplasm:
RGD
PMID:19480007
RGD:9850273
NCBI chr16:96,268,806...96,326,993
Ensembl chr16:96,268,806...96,326,993
G
Pdgfa
platelet derived growth factor, alpha
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat) mRNA, protein:increased expression:mammary gland (rat)
CTD RGD
PMID:12376462 PMID:16316942 PMID:16316942 PMID:12376462
RGD:2306898 , RGD:2292404
NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
G
Pebp1
phosphatidylethanolamine binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
G
Pgam1
phosphoglycerate mutase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099
G
Pgr
progesterone receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15637090
NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
G
Phb1
prohibitin 1
ISO
mRNA, protein:increased expression:mammary gland CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12376462 PMID:12376462
RGD:2292404
NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
G
Pin1
peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1
ISO
RGD
PMID:22064478
RGD:8693420
NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880
G
Pkm
pyruvate kinase, muscle
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
G
Plau
plasminogen activator, urokinase
disease_progression
ISO
RGD
PMID:18052026
RGD:6484140
NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
G
Plk2
polo like kinase 2
ISO
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:mammary gland (rat)
CTD RGD
PMID:12376462 PMID:12376462
RGD:2292404
NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378
G
Ppara
peroxisome proliferator activated receptor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11137312
NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
G
Prdx2
peroxiredoxin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
G
Prl
prolactin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
G
Prlr
prolactin receptor
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat)
CTD RGD
PMID:16316942 PMID:16316942
RGD:2306898
NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266
G
Psma4
proteasome subunit alpha 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 9:54,858,074...54,865,316
Ensembl chr 9:54,858,074...54,865,314
G
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr14:55,815,951...55,818,984
Ensembl chr14:55,815,580...55,818,986
G
Ptbp1
polypyrimidine tract binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr10:79,690,502...79,700,269
Ensembl chr10:79,690,261...79,700,605
G
Pten
phosphatase and tensin homolog
onset
IAGP
RGD
PMID:18381417
RGD:2292496
NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
G
Ptger1
prostaglandin E receptor 1 (subtype EP1)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11751431
NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISO IMP
mRNA:increased expression:breast
RGD
PMID:18279516 PMID:18676768 PMID:21623034
RGD:2300130 , RGD:2300118 , RGD:5135030
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
G
Ptk2
PTK2 protein tyrosine kinase 2
disease_progression
IAGP ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:24809783 PMID:18056629 PMID:15930288
RGD:2292554 , RGD:2292560
NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
G
Ptn
pleiotrophin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155
G
Ptprb
protein tyrosine phosphatase receptor type B
treatment
IMP
RGD
PMID:23899555
RGD:151660352
NCBI chr10:116,111,407...116,225,443
Ensembl chr10:116,111,428...116,225,440
G
Ran
RAN, member RAS oncogene family
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387
G
Rasa1
RAS p21 protein activator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249
G
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12606953
NCBI chr13:92,028,526...92,268,584
Ensembl chr13:92,028,519...92,268,164
G
Rb1
RB transcriptional corepressor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14522882
NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
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Rbp1
retinol binding protein 1, cellular
ISO
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:mammary gland (rat)
CTD RGD
PMID:12376462 PMID:12376462
RGD:2292404
NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628
G
Rbp4
retinol binding protein 4, plasma
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat)
CTD RGD
PMID:16316942 PMID:16316942
RGD:2306898
NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729
G
Rcn1
reticulocalbin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 2:105,216,293...105,229,664
Ensembl chr 2:105,216,636...105,229,664
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Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
IEP
protein:decreased expression:peritoneal macrophage
RGD
PMID:16288051
RGD:2298764
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
IEP
RGD
PMID:16260626
RGD:7777148
NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
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Rnpep
arginyl aminopeptidase (aminopeptidase B)
ISO
protein:increased expression:serum CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16619500 PMID:16619500
RGD:1582109
NCBI chr 1:135,190,447...135,211,765
Ensembl chr 1:135,190,450...135,211,822
G
Rpl3
ribosomal protein L3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:79,961,993...79,967,553
Ensembl chr15:79,961,992...79,976,069
G
Rpl6
ribosomal protein L6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:121,342,564...121,347,304
Ensembl chr 5:121,342,544...121,347,304
G
Rps14
ribosomal protein S14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr18:60,907,668...60,911,618
Ensembl chr18:60,880,170...60,911,618
G
Runx1
runt related transcription factor 1
ISO
mRNA:increased expression:mammary gland
RGD
PMID:29435983
RGD:126779584
NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
G
Rxra
retinoid X receptor alpha
ISO
RGD
PMID:16344269
RGD:1643109
NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
G
S100a6
S100 calcium binding protein A6 (calcyclin)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488
G
S1pr1
sphingosine-1-phosphate receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721
G
Scarb1
scavenger receptor class B, member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158
G
Scd2
stearoyl-Coenzyme A desaturase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
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Selenop
selenoprotein P
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
G
Sgk1
serum/glucocorticoid regulated kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
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Slc12a2
solute carrier family 12, member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr18:58,011,505...58,079,893
Ensembl chr18:58,011,750...58,079,893
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Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr11:120,382,663...120,391,987
Ensembl chr11:120,382,666...120,390,013
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Sncg
synuclein, gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746
G
Snrpd3
small nuclear ribonucleoprotein D3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr10:75,353,852...75,371,300
Ensembl chr10:75,353,385...75,373,215
G
Socs1
suppressor of cytokine signaling 1
IEP ISO
mRNA:increased expression:mammary gland
RGD
PMID:18381452 PMID:20354188
RGD:2298899 , RGD:21079418
NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
G
Socs3
suppressor of cytokine signaling 3
IEP
mRNA:increased expression:mammary gland
RGD
PMID:18381452
RGD:2298899
NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
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Sod2
superoxide dismutase 2, mitochondrial
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23964924
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Sox9
SRY (sex determining region Y)-box 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
G
Spint2
serine protease inhibitor, Kunitz type 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:28,955,755...28,981,484
Ensembl chr 7:28,955,748...28,981,337
G
Spp1
secreted phosphoprotein 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15318939
NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
G
Srsf2
serine and arginine-rich splicing factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920
G
Stat1
signal transducer and activator of transcription 1
IEP
RGD
PMID:11325527
RGD:2291895
NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
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Stat3
signal transducer and activator of transcription 3
IDA ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat)
CTD RGD
PMID:16316942 PMID:17483332 PMID:16316942
RGD:2291914 , RGD:2306898
NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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Stat5a
signal transducer and activator of transcription 5A
susceptibility
ISO IAGP IMP
protein:altered localization:nucleus protein:increased tyrosine phosphorylation:mammary gland CTD Direct Evidence: marker/mechanism mRNA:increased expression:mammary gland (rat) mRNA, protein:increased expression:mammary gland (rat)
CTD RGD
PMID:12376462 PMID:15609129 PMID:16316942 PMID:15609129 PMID:12082622 PMID:17173897 PMID:16316942 PMID:12376462 PMID:20181624 More...
RGD:2291932 , RGD:2298539 , RGD:2291927 , RGD:2306898 , RGD:2292404 , RGD:151665819
NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
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Stat6
signal transducer and activator of transcription 6
IDA
DNA:gene knockout::Balb/C-derived Stat6(-/-) mice resistant to growth of implanted Balb/C mammary tumors
RGD
PMID:11086031
RGD:2298563
NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
G
Stc2
stanniocalcin 2
ISO
mRNA:increased expression:mammary gland
RGD
PMID:18959458
RGD:2313895
NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074
G
Stmn1
stathmin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154
G
Tdg
thymine DNA glycosylase
IEP
mRNA:increased expression:mammary gland tumor (mouse)
RGD
PMID:9794235
RGD:2317355
NCBI chr10:82,465,649...82,486,633
Ensembl chr10:82,465,662...82,486,633
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Terc
telomerase RNA component
IEP
RNA:increased expression:mammary gland
RGD
PMID:9857231
RGD:2291975
NCBI chr 3:96,321,753...96,322,149
Ensembl chr 3:96,321,753...96,322,149
G
Tff1
trefoil factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21283680
NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251
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Tgfa
transforming growth factor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8603490
NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
G
Tgfb1
transforming growth factor, beta 1
IMP
RGD
PMID:8466857
RGD:7394797
NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
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Tgfbr1
transforming growth factor, beta receptor I
ISO
RGD
PMID:12808151
RGD:737735
NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
G
Tgfbr2
transforming growth factor, beta receptor II
ISO
RGD
PMID:12808151
RGD:737735
NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428
G
Thbs1
thrombospondin 1
ISO
mRNA:increased expression:mammary gland
RGD
PMID:15459484
RGD:1626167
NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
G
Thrsp
thyroid hormone responsive
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
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Tkt
transketolase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr14:30,271,088...30,296,681
Ensembl chr14:30,270,316...30,296,677
G
Tle4
transducin-like enhancer of split 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr19:14,425,434...14,575,542
Ensembl chr19:14,425,514...14,575,415
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Tnf
tumor necrosis factor
IMP
RGD
PMID:19755514
RGD:7401185
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfrsf10b
tumor necrosis factor receptor superfamily, member 10b
IMP
RGD
PMID:17671220
RGD:2290495
NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
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Tnfsf10
tumor necrosis factor (ligand) superfamily, member 10
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21252285
NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
G
Tpm3
tropomyosin 3, gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462 PMID:16316942
NCBI chr 3:89,979,958...90,008,209
Ensembl chr 3:89,979,956...90,008,209
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Trf
transferrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9879772 PMID:16316942
NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
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Trp53
transformation related protein 53
disease_progression
ISO IAGP EXP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:24809783 PMID:17470299 PMID:18092324
RGD:2290577 , RGD:2290539
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
G
Trps1
transcriptional repressor GATA binding 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr15:50,518,149...50,754,027
Ensembl chr15:50,518,148...50,753,859
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Tsc22d1
TSC22 domain family, member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
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Tubb2b
tubulin, beta 2B class IIB
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr13:34,310,991...34,314,337
Ensembl chr13:34,310,731...34,314,449
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Txnip
thioredoxin interacting protein
severity
ISO
mRNA:decreased expression:mammary gland
RGD
PMID:15170812
RGD:1642758
NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
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Tyms
thymidylate synthase
ISO
RGD
PMID:9635926
RGD:2315839
NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
G
Ube2i
ubiquitin-conjugating enzyme E2I
ISO
MCF-7 human breast cancer cell tumors grown in nude mice CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16316942 PMID:15735760
RGD:2301345
NCBI chr17:25,479,484...25,494,965
Ensembl chr17:25,479,482...25,493,856
G
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
G
Vamp8
vesicle-associated membrane protein 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686
G
Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor
IMP
RGD
PMID:15333467
RGD:8158073
NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
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Vegfa
vascular endothelial growth factor A
treatment
ISO
human protein in a mouse model
RGD
PMID:21890879
RGD:6771361
NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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Wap
whey acidic protein
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:16316942
NCBI chr11:6,585,483...6,588,654
Ensembl chr11:6,585,482...6,588,637
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Wnt1
wingless-type MMTV integration site family, member 1
IDA
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423 PMID:8065359
RGD:2298848 , RGD:2298863
NCBI chr15:98,687,738...98,691,711
Ensembl chr15:98,687,738...98,691,718
G
Wnt2
wingless-type MMTV integration site family, member 2
ISO
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423 PMID:8065359
RGD:2298848 , RGD:2298863
NCBI chr 6:17,988,939...18,032,771
Ensembl chr 6:17,988,939...18,030,584
G
Wnt3
wingless-type MMTV integration site family, member 3
IDA
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423
RGD:2298848
NCBI chr11:103,665,000...103,708,854
Ensembl chr11:103,664,976...103,708,783
G
Wnt3a
wingless-type MMTV integration site family, member 3A
IDA
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423 PMID:8065359
RGD:2298848 , RGD:2298863
NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578
G
Wnt5b
wingless-type MMTV integration site family, member 5B
no_association
IDA
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423 PMID:8065359
RGD:2298848 , RGD:2298863
NCBI chr 6:119,409,493...119,521,847
Ensembl chr 6:119,409,492...119,521,308
G
Wnt6
wingless-type MMTV integration site family, member 6
no_association
IDA
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423 PMID:8065359
RGD:2298848 , RGD:2298863
NCBI chr 1:74,793,499...74,824,481
Ensembl chr 1:74,811,051...74,824,481
G
Wnt7a
wingless-type MMTV integration site family, member 7A
IDA
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423 PMID:8065359
RGD:2298848 , RGD:2298863
NCBI chr 6:91,340,963...91,388,335
Ensembl chr 6:91,340,963...91,388,345
G
Wnt7b
wingless-type MMTV integration site family, member 7B
no_association
IDA
in vitro transformation of transfected C57MG mammary epithelial cell line
RGD
PMID:9419423 PMID:8065359
RGD:2298848 , RGD:2298863
NCBI chr15:85,419,638...85,466,022
Ensembl chr15:85,419,638...85,466,674
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Xdh
xanthine dehydrogenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
G
Xiap
X-linked inhibitor of apoptosis
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12766084
NCBI chr X:41,148,483...41,198,541
Ensembl chr X:41,148,556...41,198,533
G
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21283680
NCBI chr12:111,769,626...111,780,326
Ensembl chr12:111,769,626...111,780,307
G
Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12376462
NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173
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