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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Vascular System Injuries
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Accession:DOID:9000352 term browser browse the term
Definition:Injuries to blood vessels caused by laceration, contusion, puncture, or crush and other types of injuries. Symptoms vary by site and mode of injuries and may include bleeding, bruising, swelling, pain, and numbness. It does not include injuries secondary to pathologic function or diseases such as ATHEROSCLEROSIS.
Synonyms:exact_synonym: Vascular Injuries;   Vascular Injury;   Vascular System Injury
 primary_id: MESH:D057772;   RDO:0007794


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Vascular System Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chrNW_004936479:13,252,678...13,255,570
Ensembl chrNW_004936479:13,252,678...13,255,570
JBrowse link
G Apoe apolipoprotein E ISO protein:decreased expression:plasma (rat) RGD PMID:21163611 PMID:21416056 RGD:5509868 RGD:6904145 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Atp7a ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20671235 NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chrNW_004936604:551,774...567,014 JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chrNW_004936604:548,844...551,031
Ensembl chrNW_004936604:548,847...549,956
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO protein:increased expression:aorta (rat) RGD PMID:28653218 RGD:13513975 NCBI chrNW_004936599:2,437,061...2,456,141
Ensembl chrNW_004936599:2,437,032...2,456,147
JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19234301 NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311
JBrowse link
G Id2 inhibitor of DNA binding 2 ISO protein:increased expression:carotid artery, blood vessel wall (rat) RGD PMID:11706002 RGD:619536 NCBI chrNW_004936532:5,236,175...5,238,689
Ensembl chrNW_004936532:5,236,037...5,238,881
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO RGD PMID:15217908 RGD:11049588 NCBI chrNW_004936483:16,489,127...16,594,712
Ensembl chrNW_004936483:16,489,133...16,594,783
JBrowse link
G LOC101968921 angiotensin-converting enzyme susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:repeat:intron:IVS13+40(CA)?-26 (rat)
CTD
RGD
PMID:9484988 PMID:19258495 RGD:8157602 NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:19234301 NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22552115 RGD:6484736 NCBI chrNW_004936541:4,873,459...4,919,787
Ensembl chrNW_004936541:4,873,182...4,937,500
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29609002 NCBI chrNW_004936748:1,244,962...1,250,093
Ensembl chrNW_004936748:1,245,538...1,250,093
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11868353 NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19234301 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16465
    Wounds and Injuries 894
      Vascular System Injuries 15
        vascular toxicity 0
Path 2
Term Annotations click to browse term
  disease 16465
    disease of anatomical entity 14117
      cardiovascular system disease 4133
        vascular disease 2898
          Vascular System Injuries 15
            vascular toxicity 0
paths to the root