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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Vascular System Injuries
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Accession:DOID:9000352 term browser browse the term
Definition:Injuries to blood vessels caused by laceration, contusion, puncture, or crush and other types of injuries. Symptoms vary by site and mode of injuries and may include bleeding, bruising, swelling, pain, and numbness. It does not include injuries secondary to pathologic function or diseases such as ATHEROSCLEROSIS.
Synonyms:exact_synonym: Vascular Injuries;   Vascular Injury;   Vascular System Injury
 primary_id: MESH:D057772;   RDO:0007794


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Vascular System Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 susceptibility ISO DNA:repeat:intron:IVS13+40(CA)?-26 (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:9484988 PMID:19258495 RGD:8157602 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr13:88,934,873...88,980,317
Ensembl chr13:88,934,868...88,983,105 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388 		JBrowse link
G APOE apolipoprotein E ISO protein:decreased expression:plasma (rat) RGD PMID:21163611 PMID:21416056 RGD:5509868 RGD:6904145 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20671235 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr 7:117,491,350...117,492,410
Ensembl chr 7:117,491,350...117,492,410 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16982965 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,713...117,472,005 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO protein:increased expression:aorta (rat) RGD PMID:28653218 RGD:13513975 NCBI chr 2:5,209,435...5,227,543
Ensembl chr 2:5,209,439...5,227,758 		JBrowse link
G HMOX1 heme oxygenase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19234301
G ID2 inhibitor of DNA binding 2 ISO protein:increased expression:carotid artery, blood vessel wall (rat) RGD PMID:11706002 RGD:619536 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,763...127,503,257 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:19234301 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22552115 RGD:6484736 NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,649,044...14,723,293 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29609002 NCBI chr 4:117,064,632...117,069,724
Ensembl chr 4:117,064,755...117,069,650 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11868353 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19234301 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17412
    Wounds and Injuries 937
      Vascular System Injuries 15
        vascular toxicity 0
Path 2
Term Annotations click to browse term
  disease 17412
    disease of anatomical entity 14873
      cardiovascular system disease 4328
        vascular disease 3053
          Vascular System Injuries 15
            vascular toxicity 0
paths to the root