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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Abscess
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Accession:DOID:9000325 term browser browse the term
Definition:Accumulation of purulent material in tissues, organs, or circumscribed spaces, usually associated with signs of infection.
Synonyms:exact_synonym: Abscesses
 primary_id: MESH:D000038;   RDO:0002395
For additional species annotation, visit the Alliance of Genome Resources.



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Abscess term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rn interleukin 1 receptor antagonist severity ISO human protein in a rat model RGD PMID:8872492 RGD:8551794 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Lcn2 lipocalin 2 IEP mRNA,Protein:increased expression:kidney, liver, serum RGD PMID:22249220 RGD:126781756 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
Amebic Liver Abscess term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 treatment ISO RGD PMID:10862314 RGD:14928216 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il23a interleukin 23 subunit alpha ISO mRNA:increased expression:liver (mouse) RGD PMID:26809113 RGD:39458041 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphism, haplotype: :HLA-DQB1*04, HLA-DQB1*02 RGD PMID:25938667 RGD:36049810 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphism, haplotype: :HLA-DRB1*08 RGD PMID:25938667 RGD:36049810 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:10862314 RGD:14928216 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
Brain Abscess term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 ISO RGD PMID:16239543 RGD:8552881 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
Cerebral Toxoplasmosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkb1 nuclear factor kappa B subunit 1 severity ISO RGD PMID:20156658 RGD:40902838 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
Liver Abscess term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem1 triggering receptor expressed on myeloid cells 1 severity ISO associated with Klebsiella pneumonia RGD PMID:24396044 RGD:126925976 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
JBrowse link
suppurative periapical periodontitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed IEP protein:increased expression:neutrophil: RGD PMID:19913217 RGD:10450566 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18156
    Pathological Conditions, Signs and Symptoms 11300
      Pathologic Processes 7755
        Inflammation 2802
          Suppuration 101
            Abscess 11
              Abdominal Abscess + 6
              Brain Abscess + 2
              Periodontal Abscess 0
              Peritonsillar Abscess 0
              Psoas Abscess 0
              Retropharyngeal Abscess 0
              Zuska's Disease 0
              breast abscess 0
              epidural abscess 0
              lung abscess 0
              suppurative periapical periodontitis 1
paths to the root