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ONTOLOGY REPORT - ANNOTATIONS
Term:Lung Injury
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Accession:DOID:9000310 term browser browse the term
Definition:Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES.
Synonyms:exact_synonym: Chronic Lung Injuries;   Chronic Lung Injury;   Lung Injuries;   Pulmonary Injuries;   Pulmonary Injury
 primary_id: MESH:D055370;   RDO:0006082
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants       view all columns           Sort by:
 
Lung Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11554173
G Ace2 angiotensin I converting enzyme 2 JBrowse link X 32,050,734 32,095,860 RGD:11554173
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7245945
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:11554173
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:11554173
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11554173
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:11554173
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:11554173
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039441
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:7257705
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:5135486
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:11554173
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:11554173
G Elf3 E74 like ETS transcription factor 3 JBrowse link 13 52,083,873 52,088,798 RGD:11554173
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:4892252
G Fgf7 fibroblast growth factor 7 JBrowse link 3 118,315,859 118,368,464 RGD:11554173
G Fis1 fission, mitochondrial 1 JBrowse link 12 22,750,485 22,765,324 RGD:12437080
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:11554173
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:10401875
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:11554173
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:11354979
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:5509974
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G Ltf lactotransferrin JBrowse link 8 119,290,416 119,313,261 RGD:7243109
G Mme membrane metallo-endopeptidase JBrowse link 2 153,799,203 153,880,910 RGD:11554173
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6483842
RGD:11554173
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:7245567
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:10413876
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:5144062
RGD:11554173
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:5144065
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:13442477
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:11554173
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:11554173
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:11554173
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6771215
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:4143526
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:6483820
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:11554173
G Slc11a2 solute carrier family 11 member 2 JBrowse link 7 142,025,812 142,062,892 RGD:5688724
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:5147820
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:11554173
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:11554173
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:11554173
Acute Lung Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:11554173
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:10755331
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686380
RGD:8695940
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:6480481
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:7244254
G Akap12 A-kinase anchoring protein 12 JBrowse link 1 40,816,130 40,906,582 RGD:14348970
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6483494
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:5509626
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:11554173
G Aqp5 aquaporin 5 JBrowse link 7 141,249,044 141,252,576 RGD:11553933
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:11554173
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:10054109
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:10054109
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:11040808
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13782288
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:13782288
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:11554173
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:10045573
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480432
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:68880
RGD:6480432
RGD:5683874
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:5688151
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893505
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:5135253
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:5135247
RGD:11554173
RGD:5147925
RGD:5135253
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:5135247
RGD:5135256
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:7257703
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:5135235
RGD:5147744
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:5147744
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:11554173
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:5131862
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450548
RGD:10450587
RGD:10450585
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:11554173
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:5688354
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:7387313
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:11341740
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:11341811
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:11554173
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:11554173
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:5147925
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:5147925
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:5147925
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:7387313
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:5684427
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:8662452
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:13504847
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:7257562
G Gzmb granzyme B JBrowse link 15 35,413,862 35,417,293 RGD:5135517
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:4892587
RGD:10402098
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:5508470
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145326
RGD:4140418
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:10054390
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:8547719
RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480432
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364984
RGD:14975158
RGD:7365008
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:4145512
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:11554173
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655952
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4142807
RGD:7204498
RGD:6480432
RGD:4142531
RGD:4143193
G Il1rl1 interleukin 1 receptor-like 1 JBrowse link 9 47,133,483 47,184,316 RGD:5144222
RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4143193
RGD:4143168
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480432
G Il22 interleukin 22 JBrowse link 7 61,236,037 61,240,502 RGD:4888524
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:10402798
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11062103
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:6482199
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:11531100
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:5684427
G Mfn1 mitofusin 1 JBrowse link 2 118,929,738 118,971,689 RGD:12437080
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12437080
G Mir155 microRNA 155 JBrowse link 11 24,176,603 24,176,667 RGD:21066348
RGD:24922218
RGD:21408593
G Mir223 microRNA 223 JBrowse link X 65,367,812 65,367,921 RGD:21408568
G Mir330 microRNA 330 JBrowse link 1 80,092,681 80,092,777 RGD:11553933
G Mir96 microRNA 96 JBrowse link 4 57,463,366 57,463,471 RGD:11553933
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:13207316
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:9685338
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:13207316
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6909173
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:11554173
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:11554173
G Mylk myosin light chain kinase JBrowse link 11 69,013,060 69,260,039 RGD:1581052
RGD:11554173
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:11554173
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:5144065
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:8547530
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:5147744
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:7247713
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:11035223
RGD:13442501
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:12437080
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:6480522
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:11533951
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:11075069
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:9835397
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6483494
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma JBrowse link 6 51,465,696 51,501,234 RGD:6482677
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:6482722
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:5147760
RGD:7241552
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:8553030
RGD:11554173
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:6484539
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:11100043
RGD:11250405
G Procr protein C receptor JBrowse link 3 151,285,321 151,289,581 RGD:13515130
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5135287
RGD:5135496
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:5143982
RGD:5144142
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:11035256
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:11075078
RGD:11080967
RGD:11080962
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:8661650
G Sftpa1 surfactant protein A1 JBrowse link 16 18,716,019 18,719,404 RGD:4143451
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:11554173
G Slpi secretory leukocyte peptidase inhibitor JBrowse link 3 160,799,979 160,802,228 RGD:9999422
RGD:9999425
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:5147812
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:5147819
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:11554173
G Tff2 trefoil factor 2 JBrowse link 20 9,872,669 9,876,008 RGD:11554173
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:11554173
G Thbd thrombomodulin JBrowse link 3 142,748,673 142,752,325 RGD:5131887
RGD:13515130
RGD:5685372
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:9999422
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:5135496
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480432
RGD:14995473
RGD:14975158
RGD:5147925
G Tnfaip6 TNF alpha induced protein 6 JBrowse link 3 37,545,238 37,564,704 RGD:11554173
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:5684427
G Vip vasoactive intestinal peptide JBrowse link 1 42,169,307 42,177,582 RGD:4145303
RGD:11554173
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:13209002
anthracosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 JBrowse link 13 90,605,792 90,642,032 RGD:11554173
G Flacc1 flagellum associated containing coiled-coil domains 1 JBrowse link 9 65,665,663 65,693,822 RGD:11554173
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:11554173
G Rbm26 RNA binding motif protein 26 JBrowse link 15 89,262,683 89,339,323 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
asbestosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:11554173
G Atf6 activating transcription factor 6 JBrowse link 13 89,053,457 89,242,531 RGD:11554173
G Cfd complement factor D JBrowse link 7 12,634,216 12,635,939 RGD:11554173
G Clca1 chloride channel accessory 1 JBrowse link 2 250,897,980 250,923,711 RGD:4145655
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:4892076
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:11554173
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:4889408
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:5490588
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:11554173
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:11554173
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:11554173
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4891441
RGD:11554173
RGD:4891438
G Prdx1 peroxiredoxin 1 JBrowse link 5 135,536,413 135,551,986 RGD:11554173
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:11554173
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:11554173
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:11554173
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:4889594
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Tpm4 tropomyosin 4 JBrowse link 16 19,385,810 19,399,851 RGD:11554173
berylliosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11554173
G Btnl2 butyrophilin-like 2 JBrowse link 20 4,140,184 4,156,365 RGD:9685029
RGD:11554173
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:4892065
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:11554173
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:11554173
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145349
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:11554173
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:11554173
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:4145294
RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
Bronchopulmonary Dysplasia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:11537057
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:11537057
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:11537057
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:11537057
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:11537057
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:5130750
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:5130981
G Cd209c CD209c molecule JBrowse link 12 2,837,991 2,846,709 RGD:5131185
G Chi3l1 chitinase 3 like 1 JBrowse link 13 51,022,844 51,030,797 RGD:4892651
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:5134972
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:11537474
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:4144841
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:10395385
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:10402122
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:12792215
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:4142520
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:12792215
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:10395385
RGD:11537057
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4143172
RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4143172
RGD:12910846
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:12910846
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:4891007
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5129685
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:5131170
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:11554173
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:5144211
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:13208551
G Sftpa1 surfactant protein A1 JBrowse link 16 18,716,019 18,719,404 RGD:4143384
RGD:4144876
G Sftpb surfactant protein B JBrowse link 4 100,166,855 100,175,941 RGD:4143405
RGD:4143384
RGD:4143418
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:4143384
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:12904049
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11537057
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:13432055
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:10395369
Hyperoxic Lung Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:4892072
RGD:11576318
RGD:11576306
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450581
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:11567262
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:10755753
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:13204816
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:10769360
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:10769360
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:10449500
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:12859031
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:12859031
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:13209004
Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fam189a1 family with sequence similarity 189, member A1 JBrowse link 1 125,552,990 125,967,984 RGD:8554872
G Nsmce3 NSE3 homolog, SMC5-SMC6 complex component JBrowse link 1 125,663,987 125,665,314 RGD:8554872
RGD:7240710
Lung Reperfusion Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:10054119
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:10054119
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:10054119
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:10395282
RGD:10395299
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450582
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402095
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:10755577
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:7240537
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7183185
RGD:7204125
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:10402797
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5129703
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:7240537
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:4892012
RGD:11533932
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6771212
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6771212
RGD:11541083
G Proc protein C, inactivator of coagulation factors Va and VIIIa JBrowse link 18 24,918,402 24,928,822 RGD:11100035
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547720
RGD:11080966
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:10402095
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4143397
meconium aspiration syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:11039054
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:11039054
G Atf2 activating transcription factor 2 JBrowse link 3 60,721,137 60,795,951 RGD:13592920
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:5144123
pneumoconiosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acan aggrecan JBrowse link 1 140,762,758 140,824,441 RGD:11554173
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:11554173
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:11554173
G Car1 carbonic anhydrase 1 JBrowse link 2 88,185,204 88,227,486 RGD:11554173
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:5130756
G Cdh23 cadherin-related 23 JBrowse link 20 29,857,018 30,263,758 RGD:11554173
G H3f4 H3.4 histone JBrowse link 10 45,304,696 45,305,106 RGD:11554173
G Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 JBrowse link 10 14,122,856 14,128,984 RGD:11554173
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:11554173
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
G Mdm4 MDM4 regulator of p53 JBrowse link 13 49,786,776 49,828,780 RGD:11554173
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 JBrowse link 4 49,941,046 50,140,764 RGD:11554173
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:7421557
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:11554173
G Tmprss3 transmembrane serine protease 3 JBrowse link 20 9,910,522 9,929,705 RGD:11554173
Pneumonia, Ventilator-Associated term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gc GC, vitamin D binding protein JBrowse link 14 20,267,023 20,302,577 RGD:5509873
Pulmonary Contusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11060268
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11060268
Radiation Pneumonitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:4890434
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129484
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:5129484
G Ccl17 C-C motif chemokine ligand 17 JBrowse link 19 10,619,220 10,620,671 RGD:4145517
G Ccl22 C-C motif chemokine ligand 22 JBrowse link 19 10,674,189 10,681,145 RGD:4145517
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:5131286
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:5131286
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:5131286
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:5131286
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:4143486
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:4145121
RGD:4145278
RGD:4145136
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:5131286
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:5131153
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:5129484
silicosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:11554173
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4143368
RGD:11554173
G Arpc2 actin related protein 2/3 complex, subunit 2 JBrowse link 9 81,518,163 81,548,871 RGD:4893904
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129516
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11554173
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6483764
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:11041147
G Chia chitinase, acidic JBrowse link 2 208,750,348 208,797,388 RGD:4893904
G Cpm carboxypeptidase M JBrowse link 7 60,654,350 60,714,620 RGD:11554173
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:10450467
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:4891515
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:5131937
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:9585691
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:4145384
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 JBrowse link 3 62,481,222 62,491,356 RGD:10059658
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:4888525
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:4142816
RGD:8551847
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:4891500
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:11554173
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:10043156
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:4891445
RGD:11554173
G Pdzrn4 PDZ domain containing RING finger 4 JBrowse link 7 133,856,101 134,004,250 RGD:11554173
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:1625527
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4142816
RGD:10450591
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:5131150
Ventilator-Induced Lung Injury term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:5509080
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903342
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:10450549
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:5509080
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402091
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364989
RGD:11049495
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:4142534
RGD:6482672
RGD:4142537
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:2311107
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:6909178
G Il22 interleukin 22 JBrowse link 7 61,236,037 61,240,502 RGD:5147406
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:10412643
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:9685338
RGD:9685370
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:5130156
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:10413863
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma JBrowse link 6 51,465,696 51,501,234 RGD:6482697
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5134956
G Scgb1a1 secretoglobin family 1A member 1 JBrowse link 1 225,279,698 225,283,246 RGD:5144143
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:11081010
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:5147811
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15610
    Wounds and Injuries 816
      Thoracic Injuries 243
        Lung Injury 238
          Acute Lung Injury 121
          Hyperoxic Lung Injury 11
          Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome 2
          Lung Reperfusion Injury + 20
          Pulmonary Contusion 2
          Radiation Pneumonitis 15
          Ventilator-Induced Lung Injury + 49
          meconium aspiration syndrome 4
          pneumoconiosis + 70
Path 2
Term Annotations click to browse term
  disease 15610
    disease of anatomical entity 14968
      respiratory system disease 2463
        lower respiratory tract disease 1481
          lung disease 1440
            Lung Injury 238
              Acute Lung Injury 121
              Hyperoxic Lung Injury 11
              Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome 2
              Lung Reperfusion Injury + 20
              Pulmonary Contusion 2
              Radiation Pneumonitis 15
              Ventilator-Induced Lung Injury + 49
              meconium aspiration syndrome 4
              pneumoconiosis + 70
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.