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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Lung Injury
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Accession:DOID:9000310 term browser browse the term
Definition:Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES.
Synonyms:exact_synonym: Lung Injuries;   Pulmonary Injuries;   Pulmonary Injury
 narrow_synonym: Chronic Lung Injuries;   Chronic Lung Injury
 primary_id: MESH:D055370
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
Lung Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16001071 PMID:33007385 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16001071 PMID:19864379 PMID:20484496 PMID:33007385 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP associated with Hyperoxia; mRNA, protein:increased expression:lung (rat) RGD PMID:22093994 RGD:7245945 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:25831079 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:30953400 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19762220 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19762220 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19762220 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Csf3 colony stimulating factor 3 ISO RGD PMID:14585735 RGD:11039441 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:15347560 RGD:7257705 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:17086735 RGD:5135486 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24893714 PMID:25703676 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25703676 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:21709667 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481 		JBrowse link
G Esr2 estrogen receptor 2 IDA associated with Shock, Hemorrhagic RGD PMID:20195535 RGD:4892252 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fgf7 fibroblast growth factor 7 ISO CTD Direct Evidence: therapeutic CTD PMID:18385170 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fis1 fission, mitochondrial 1 IEP protein:increased expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr12:19,708,558...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Foxp3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28630656 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24479952 RGD:10401875 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17365036 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO associated with Bacteremia; RGD PMID:24891762 RGD:11354979 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Igf2 insulin-like growth factor 2 IEP RGD PMID:9160836 RGD:5509974 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19762220 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ltf lactotransferrin ISO RGD PMID:16905637 RGD:7243109 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Mme membrane metallo-endopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21114838 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mt2A metallothionein 2A ISO mRNA:increased expression:lung (mouse)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:18528683 PMID:17215068 RGD:6483842 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:22483544 RGD:7245567 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mx1 MX dynamin like GTPase 1 ISO mRNA: increased expression: lung (mouse) RGD PMID:31921151 RGD:126779575 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507 		JBrowse link
G Nfkbia NFKB inhibitor alpha IEP associated with Reperfusion Injury RGD PMID:19321049 RGD:10413876 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:respiratory system fluid/secretion
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:20075049 PMID:20075049 RGD:5144062 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:17673270 RGD:5144065 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IEP associated with Diabetes Mellitus, Experimental;protein:decreased expression:lung (rat) RGD PMID:27888691 RGD:13442477 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20075049 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16127429 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdgfd platelet derived growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:25280005 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased tyrosine phosphorylation:lung (mouse) RGD PMID:22806890 RGD:6771215 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Plau plasminogen activator, urokinase IEP associated with Hyperoxia RGD PMID:19099788 RGD:4143526 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO associated with Hyperoxia RGD PMID:19435793 RGD:6483820 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO CTD Direct Evidence: therapeutic CTD PMID:33033841 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:24633890 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 ISO RGD PMID:20336479 RGD:5688724 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:17565047 RGD:5147820 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tgfa transforming growth factor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:11919079 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22300504 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnc tenascin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18978301 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2518282 PMID:26243812 PMID:34255241 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:10781441 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
Acute Lung Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme treatment ISO associated wit Escherichia coli Infections RGD PMID:29990483 RGD:40400897 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 severity
treatment		 ISO CTD Direct Evidence: therapeutic
associated with Escherichia coli Infections
associated with avian influenza;protein:decreased expression:lung (mouse)
human protein in a mouse model		 CTD
RGD		 PMID:27302421 PMID:16001071 PMID:29990483 PMID:25391767 PMID:16001071 RGD:32716389, RGD:40400897, RGD:40818412, RGD:32716389 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acvr1 activin A receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297076 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Adar adenosine deaminase, RNA-specific treatment IMP RGD PMID:18520702 RGD:10755331 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO associated with Sepsis RGD PMID:22156343 PMID:23522481 RGD:5686380, RGD:8695940 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adra2a adrenoceptor alpha 2A IEP RGD PMID:21542970 RGD:6480481 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Aff4 ALF transcription elongation factor 4 treatment IEP RGD PMID:31466050 RGD:155631268 NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP associated with Hyperoxia; protein:decreased expression:bronchoalveolar lavage fluid (rat) RGD PMID:23576805 RGD:7244254 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akap12 A-kinase anchoring protein 12 IEP mRNA,protein:increased expression:lung RGD PMID:23912647 RGD:14348970 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 severity ISO RGD PMID:23904165 RGD:38676478 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin IDA RGD PMID:22592748 RGD:6483494 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:19752233 RGD:5509626 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: therapeutic CTD PMID:20972769 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Aqp5 aquaporin 5 IEP associated with Disseminated Intravascular Coagulation;mRNA,protein:decreased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20554700 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP associated with Endotoxemia RGD PMID:20663300 RGD:10054109 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G C3 complement C3 treatment IEP RGD PMID:22763771 RGD:11040808 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Casp12 caspase 12 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:32062619 PMID:29755641 RGD:13782288 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:29755641 RGD:13782288 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD PMID:15612528 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 treatment IEP RGD PMID:24919947 RGD:10045573 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA, protein:increased expression:lung RGD PMID:21767135 RGD:6480432 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 IMP
IEP
ISO		 mRNA, protein:increased expression:lung
protein:increased expression:respiratory system fluid/secretion 		RGD PMID:10679105 PMID:21767135 PMID:21906407 RGD:68880, RGD:6480432, RGD:5683874 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO associated with Pancreatitis RGD PMID:17312463 RGD:5688151 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd36 CD36 molecule ISO associated with Malaria RGD PMID:18483551 RGD:6893505 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO associated with Sepsis;mRNA:increased expression:lung RGD PMID:10069420 RGD:5135253 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO
IEP		 mRNA, protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:respiratory system fluid/secretion
associated with Sepsis;mRNA:increased expression:lung		 CTD
RGD		 PMID:27525872 PMID:15557650 PMID:19106808 PMID:10069420 RGD:5135247, RGD:5147925, RGD:5135253 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO
IMP		 mRNA, protein:increased expression:lung
associated with Reperfusion Injury		 RGD PMID:15557650 PMID:7814607 RGD:5135247, RGD:5135256 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 treatment ISO associated with Pancreatitis RGD PMID:17014919 RGD:7257703 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO
IEP		 mRNA:increased expression:lung RGD PMID:18367723 PMID:16882535 RGD:5135235, RGD:5147744 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEP RGD PMID:16882535 RGD:5147744 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 treatment ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16625121 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:20935109 RGD:5131862 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP
IEP		 associated with Shock, Hemorrhagic;
protein:increased expression:perfusate:		 RGD PMID:15257085 PMID:17203197 PMID:18283562 RGD:10450548, RGD:10450587, RGD:10450585 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26840748 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ephx2 epoxide hydrolase 2 IDA RGD PMID:22051199 RGD:5688354 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G F2 coagulation factor II IDA RGD PMID:22804886 RGD:7387313 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:increased expression: respiratory system fluid/secretion RGD PMID:21964405 RGD:11341740 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fadd Fas associated via death domain treatment IEP associated with Shock, Hemorrhagic RGD PMID:24122010 RGD:11341811 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:11778176 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fcgr1a Fc gamma receptor 1A IMP RGD PMID:19106808 RGD:5147925 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Fcgr2a Fc gamma receptor 2A IMP RGD PMID:19106808 RGD:5147925 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fcgr2b Fc gamma receptor 2B treatment IMP RGD PMID:19106808 RGD:5147925 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fga fibrinogen alpha chain IEP protein:increased expression:blood (rat) RGD PMID:22804886 RGD:7387313 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IMP associated with Endotoxemia RGD PMID:21528367 RGD:5684427 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Foxa1 forkhead box A1 IEP mRNA,protein:increased expression:lung RGD PMID:19649697 RGD:151665511 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP RGD PMID:23576849 RGD:8662452 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IEP protein:decreased expression:lung (rat) RGD PMID:25581610 RGD:13504847 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gsr glutathione-disulfide reductase IEP RGD PMID:7896613 RGD:7257562 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gzmb granzyme B ISO RGD PMID:20018616 RGD:5135517 NCBI chr15:30,343,361...30,346,792
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP associated with Endotoxemia
associated with Crush Injuries
associated with Burns		 RGD PMID:19766246 PMID:30465396 PMID:23874764 RGD:4892587, RGD:34901874, RGD:10402098 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:16922808 RGD:5508470 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP
IEP		 associated with Reperfusion Injury RGD PMID:20850789 PMID:20360627 RGD:4145326, RGD:4140418 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C ISO protein:altered localization:lung (mouse) RGD PMID:19029002 RGD:10054390 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP associated with Crush Injuries RGD PMID:30465396 RGD:34901874 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17973899 PMID:27525872 PMID:20569121 RGD:8547719 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 treatment ISO RGD PMID:25278421 RGD:39939031 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ifng interferon gamma IEP RGD PMID:21767135 RGD:6480432 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il10 interleukin 10 treatment
no_association		 IDA
ISO
IEP		 DNA:SNP:promoter:rs3021097 (human)
DNA:SNP:promoter:-1082G>A (rs1800896) (human)
associated with Reperfusion Injury;protein:increased expression:lung, plasma		 RGD PMID:23902576 PMID:30412745 PMID:30412745 PMID:23801594 RGD:7364984, RGD:14975158, RGD:14975158, RGD:7365008 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il13 interleukin 13 IEP mRNA:increased expression:lung RGD PMID:15461830 RGD:4145512 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28600744 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 treatment IEP associated with Myocardial Reperfusion Injury RGD PMID:24223666 RGD:8655952 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta ISO
IDA
IEP		 protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:lung
protein:increased expression:serum		 CTD
RGD		 PMID:32062619 PMID:20153312 PMID:22982561 PMID:21767135 PMID:20663306 More... RGD:4142807, RGD:7204498, RGD:6480432, RGD:4142531, RGD:4143193 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:21352201 PMID:21352201 RGD:5144222 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IMP
IEP		 mRNA:increased expression:lung RGD PMID:8613550 PMID:15970097 RGD:4143193, RGD:4143168 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:21767135 RGD:6480432 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il22 interleukin 22 ISO RGD PMID:20498020 RGD:4888524 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186 		JBrowse link
G Il4 interleukin 4 treatment IEP RGD PMID:24681349 RGD:10402798 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 IEP
ISO		 protein:increased expression:bronchoalveolar lavage, blood, lung (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:32062619 PMID:19995278 RGD:11062103 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA, protein:increased expression:lung (mouse) RGD PMID:21577093 RGD:36049795 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Itgb2 integrin subunit beta 2 IMP RGD PMID:1374449 RGD:6482199 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Jak3 Janus kinase 3 ISO RGD PMID:22359619 RGD:11531100 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Kdr kinase insert domain receptor IEP associated with Endotoxemia;mRNA, protein:decreased expression:lung RGD PMID:21528367 RGD:5684427 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 severity ISO associated with Endotoxemia RGD PMID:27703200 RGD:40903067 NCBI chr15:29,258,427...29,260,340
Ensembl chr15:29,259,240...29,260,316 		JBrowse link
G Mfn1 mitofusin 1 IEP mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mfn2 mitofusin 2 IEP mRNA, protein:increased expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir155 microRNA 155 treatment ISO
IMP		 associated with sepsis;miRNA:increased expression:lung
associated with Sepsis		 RGD PMID:30220274 PMID:27371731 PMID:27371731 PMID:28125526 PMID:31949845 RGD:21066348, RGD:11566124, RGD:11566124, RGD:24922218, RGD:21408593 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir21 microRNA 21 IEP RNA:increased expression:lung RGD PMID:30542412 RGD:41410885 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir223 microRNA 223 severity
treatment		 ISO
IEP		 RGD PMID:28931657 PMID:32226458 RGD:21408568, RGD:26884341 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir330 microRNA 330 IEP associated with Disseminated Intravascular Coagulation;RNA:increased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274 		JBrowse link
G Mir96 microRNA 96 IEP associated with Disseminated Intravascular Coagulation;RNA:increased expression:lung: RGD PMID:24806323 RGD:11553933 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Mir99b microRNA 99b ISO CTD Direct Evidence: therapeutic CTD PMID:33109608 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:23040778 RGD:13207316 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp7 matrix metallopeptidase 7 IEP associated with Sepsis RGD PMID:21567117 RGD:9685338 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:23040778 RGD:13207316 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase ISO associated with Kidney Reperfusion Injury; protein:increased expression:lung RGD PMID:22092133 RGD:6909173 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16166738 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mylk myosin light chain kinase ISO associated with Sepsis
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19374788 PMID:16399953 RGD:1581052 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24812154 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngf nerve growth factor ISO RGD PMID:17673270 RGD:5144065 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33012731 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 treatment IDA associated with Sepsis RGD PMID:22575870 RGD:8547530 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nos2 nitric oxide synthase 2 IMP RGD PMID:16882535 RGD:5147744 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:23422200 RGD:7247713 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP
IDA		 RGD PMID:24669282 PMID:28065220 RGD:11035223, RGD:13442501 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP mRNA, protein:altered expression:lung (rat) RGD PMID:25560372 RGD:12437080 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G P2ry12 purinergic receptor P2Y12 IMP associated with Shock, Hemorrhagic RGD PMID:21841533 RGD:6480522 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IDA DNA:hypermethylation RGD PMID:23546543 RGD:11533951 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO associated with Pancreatitis, Experimental, Acute RGD PMID:16127429 RGD:11075069 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP mRNA,protein:increased expression:lung,blood vessel: RGD PMID:17136598 RGD:9835397 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:22592748 RGD:6483494 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO associated with Endotoxemia;mRNA, protein:increased expression:lung (mouse) RGD PMID:31167111 RGD:41410778 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO associated with endotoxemia RGD PMID:22198681 PMID:11714830 RGD:6482677, RGD:38599213 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Pla2g2a phospholipase A2 group IIA severity IEP RGD PMID:19235614 RGD:6482722 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Plau plasminogen activator, urokinase treatment IDA associated with Endotoxemia RGD PMID:21473829 PMID:23324284 RGD:5147760, RGD:7241552 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP
ISO		 protein:decreased expression:lung (rat)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:21153920 PMID:16083301 RGD:8553030 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prdm1 PR/SET domain 1 ISO CTD Direct Evidence: therapeutic CTD PMID:33109608 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:21595935 RGD:6484539 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO associated with Pseudomonas Infections
associated with Intestinal Reperfusion Injury		 RGD PMID:16553944 PMID:18367148 RGD:11100043, RGD:11250405 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Procr protein C receptor treatment IEP RGD PMID:20095324 RGD:13515130 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO
IEP		 protein:increased expression:lung RGD PMID:20926798 PMID:19567182 RGD:5135287, RGD:5135496 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 IEP
ISO		 protein:decreased expression:lung RGD PMID:18420837 PMID:16226776 RGD:5143982, RGD:5144142 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO associated with Endotoxemia RGD PMID:17940748 RGD:11035256 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Serpine1 serpin family E member 1 treatment IDA
IEP		 associated with Shock, Hemorrhagic;mRNA:increased expression:lung (rat)
associated with Sepsis		 RGD PMID:25934465 PMID:10745022 PMID:18182560 RGD:11075078, RGD:11080967, RGD:11080962 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:11685347 RGD:8661650 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Sftpa1 surfactant protein A1 ISO mRNA, protein:increased expression:pneumocyte RGD PMID:8569184 RGD:4143451 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Sftpb surfactant protein B treatment IEP RGD PMID:22295533 RGD:151667443 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpd surfactant protein D ISO CTD Direct Evidence: therapeutic CTD PMID:30060251 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor severity
treatment		 IMP
IEP		 associated with Endotoxemia RGD PMID:10092827 PMID:25466948 RGD:9999422, RGD:9999425 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Tac1 tachykinin, precursor 1 ISO RGD PMID:19797759 RGD:5147812 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO mRNA:increased expression:lung RGD PMID:18523300 RGD:5147819 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tff1 trefoil factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19880587 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tff2 trefoil factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19880587 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16100012 PMID:25278421 RGD:39939031 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thbd thrombomodulin treatment ISO
IEP		 associated with Endotoxemia RGD PMID:19342415 PMID:20095324 PMID:19536047 RGD:5131887, RGD:13515130, RGD:5685372 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 severity IMP RGD PMID:10092827 RGD:9999422 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tlr4 toll-like receptor 4 IEP RGD PMID:19567182 RGD:5135496 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor treatment
no_association		 IEP
ISO		 mRNA, protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
associated with Liver Reperfusion Injury
DNA:SNP:promoter:rs1799964 (human)
DNA:SNP:promoter:-308G>A (rs1800629) (human)
protein:increased expression:respiratory system fluid/secretion		 CTD
RGD		 PMID:34390737 PMID:21767135 PMID:11129814 PMID:30412745 PMID:30412745 More... RGD:6480432, RGD:14995473, RGD:14975158, RGD:14975158, RGD:5147925 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO CTD Direct Evidence: therapeutic CTD PMID:26313688 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 exacerbates
ameliorates		 IMP
IDA		 RGD PMID:26832696 PMID:26832696 RGD:127284840, RGD:127284840 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16298680 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 ISO CTD Direct Evidence: therapeutic CTD PMID:33930521 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Vegfa vascular endothelial growth factor A IEP associated with Endotoxemia;mRNA, protein:altered expression:lung, plasma RGD PMID:21528367 RGD:5684427 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vip vasoactive intestinal peptide IDA
ISO		 associated with Endotoxemia
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:8643465 PMID:20441697 RGD:4145303 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:9655743 RGD:13209002 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A severity ISO associated with toxic shock syndrome RGD PMID:23422584 RGD:39938961 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
anthracosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687 		JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Rbm26 RNA binding motif protein 26 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394417 NCBI chr15:81,884,783...81,964,245
Ensembl chr15:81,887,219...81,964,118 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20005085 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
asbestosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26699812 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Atf6 activating transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Cfd complement factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:22832039 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Clca1 chloride channel accessory 1 ISO mRNA, protein:increased expression:lung RGD PMID:17637221 RGD:4145655 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO mRNA:decreased expression:leukocyte RGD PMID:20514434 RGD:4892076 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ephx1 epoxide hydrolase 1 susceptibility ISO DNA:SNP:exon:p.Y113H (rs1051740) (human) RGD PMID:17159790 RGD:4889408 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : RGD PMID:9055949 RGD:5490588 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17563610 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25324550 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8473757 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24142982 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:lung		 CTD
RGD		 PMID:12160931 PMID:12160931 PMID:12051993 RGD:4891441, RGD:4891438 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12368052 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16221779 PMID:21514415 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tnc tenascin C ISO protein:increased expression:pleura RGD PMID:10950882 RGD:4889594 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8473757 PMID:20486865 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984 		JBrowse link
berylliosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:10194187 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO DNA:SNP: :rs3117099(human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17927685 PMID:17927685 RGD:9685029 NCBI chr20:4,490,904...4,502,557
Ensembl chr20:4,489,517...4,503,341 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 disease_progression ISO DNA:polymorphisms:5' utr:multiple (human) RGD PMID:20075058 RGD:4892065 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cd28 Cd28 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12952926 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16766924 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Hmox1 heme oxygenase 1 ISO protein:increased activity:sputum RGD PMID:19453654 RGD:4145349 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8977230 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16272364 PMID:17927685 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 severity ISO DNA:polymorphisms: :-509C>T (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15750822 PMID:17785866 PMID:17785866 RGD:4145294 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8428540 PMID:12449171 PMID:15127972 PMID:16980557 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Bronchopulmonary Dysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator IEP RGD PMID:26431790 RGD:11537057 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bid BH3 interacting domain death agonist IEP RGD PMID:26431790 RGD:11537057 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 IEP RGD PMID:26431790 RGD:11537057 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 IEP RGD PMID:26431790 RGD:11537057 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 IEP RGD PMID:26431790 RGD:11537057 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase IDA RGD PMID:19693467 RGD:5130750 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO RGD PMID:16888287 RGD:5130981 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Cd209c CD209c molecule ISO RGD PMID:20050784 RGD:5131185 NCBI chr12:1,936,233...1,943,841
Ensembl chr12:1,936,396...1,942,040 		JBrowse link
G Cd209d CD209d molecule ISO RGD PMID:20050784 RGD:5131185 NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:decreased secretion:lung, secretion (human) RGD PMID:20558631 RGD:4892651 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP RGD PMID:19951473 RGD:5134972 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Dag1 dystroglycan 1 ISO DNA:SNP: :p.N494H (human) RGD PMID:17196572 RGD:11537474 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Edn1 endothelin 1 IEP protein:increased expression:lung (rat) RGD PMID:20647310 RGD:4144841 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment IEP RGD PMID:23065129 RGD:10395385 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO RGD PMID:22003089 RGD:10402122 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion, haplotype:: (human) RGD PMID:24120392 RGD:12792215 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:exon:p.I105V (human) RGD PMID:14726935 RGD:4142520 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion, haplotype:: (human) RGD PMID:24120392 RGD:12792215 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP RGD PMID:23065129 PMID:26431790 RGD:10395385, RGD:11537057 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16813970 PMID:15539764 RGD:4143172 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO protein:increased expression:lung
associated with Premature Birth;DNA:polymorphism::		 RGD PMID:15539764 PMID:22882323 RGD:4143172, RGD:12910846 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Itga3 integrin subunit alpha 3 ISO ClinVar Annotator: match by term: Bronchopulmonary dysplasia ClinVar PMID:25741868 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO associated with Premature Birth;DNA:polymorphism:exon: RGD PMID:22882323 RGD:12910846 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mif macrophage migration inhibitory factor ISO associated with Respiratory Distress Syndrome, Newborn; protein:increased expression:lung RGD PMID:18097062 RGD:4891007 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:19097983 RGD:5129685 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Muc1 mucin 1, cell surface associated severity ISO protein:increased expression:cord plasma RGD PMID:18025794 RGD:5131170 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Nfkbia NFKB inhibitor alpha exacerbates ISO DNA:SNPs:promoter: (rs2233406, rs2233409) (human) RGD PMID:23487427 RGD:40902982 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Postn periostin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363622 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO RGD PMID:11435254 RGD:5144211 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
G Serpine1 serpin family E member 1 ISO associated with Premature Birth;protein:increased expression:blood: RGD PMID:25140773 RGD:13208551 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sftpa1 surfactant protein A1 susceptibility ISO DNA:snps, haplotypes:multiple (human)
DNA:polymorphisms, haplotype: (human)		 RGD PMID:17264398 PMID:11105614 RGD:4143384, RGD:4144876 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Sftpb surfactant protein B susceptibility ISO DNA:deletion:intron (human)
DNA:SNPs:5'UTR,exon:
DNA:polymorphism:intron (human)		 RGD PMID:15102713 PMID:26045806 PMID:17264398 PMID:12424586 RGD:4143405, RGD:11085373, RGD:4143384, RGD:4143418 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpd surfactant protein D ISO RGD PMID:17264398 RGD:4143384 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Tnf tumor necrosis factor severity
no_association		 ISO DNA:SNP:promoter:-238A>G (human)
DNA:SNP:promoter:-308G>A (human)		 RGD PMID:15286263 PMID:15286263 RGD:12904049, RGD:12904049 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 IEP RGD PMID:26431790 RGD:11537057 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20812253 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Vdr vitamin D receptor susceptibility ISO associated with Premature Birth;DNA:SNPs: :rs2228570,rs731236(human) RGD PMID:24796371 RGD:13432055 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IEP mRNA:increased expression:lung RGD PMID:22305384 RGD:10395369 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
Hyperoxic Lung Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 treatment IDA
ISO		 RGD PMID:15958656 PMID:21745492 PMID:24893714 RGD:4892072, RGD:11576318, RGD:11576306 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:11104832 RGD:10450581 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:12626345 RGD:11567262 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:23475767 RGD:10755753 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Mir21 microRNA 21 exacerbates
ameliorates		 IMP
IDA		 RGD PMID:28627345 PMID:31537223 RGD:41404708, RGD:41404709 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:25760549 RGD:13204816 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:16678022 RGD:10769360 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 ISO RGD PMID:16678022 RGD:10769360 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA:increased expression:lung: RGD PMID:2696512 RGD:10449500 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Ptch1 patched 1 IEP mRNA, protein:increased expression:lung RGD PMID:22641469 RGD:12859031 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Shh sonic hedgehog signaling molecule IEP mRNA, protein:increased expression:lung RGD PMID:22641469 RGD:12859031 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Xdh xanthine dehydrogenase IEP RGD PMID:2549869 RGD:13209004 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entrep2 endosomal transmembrane epsin interactor 2 ISO ClinVar Annotator: match by term: Lung disease, immunodeficiency, and chromosome breakage syndrome ClinVar PMID:20864041 PMID:25741868 PMID:27427983 PMID:28492532 NCBI chr 1:118,288,365...118,700,514
Ensembl chr 1:118,288,379...118,700,671 		JBrowse link
G Nsmce3 NSE3 homolog, SMC5-SMC6 complex component ISO ClinVar Annotator: match by term: Lung disease, immunodeficiency, and chromosome breakage syndrome OMIM
ClinVar		 PMID:20864041 PMID:25741868 PMID:27427983 PMID:28492532 NCBI chr 1:118,401,302...118,402,629 JBrowse link
Lung Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator treatment
ameliorates		 IEP
ISO		 RGD PMID:23953793 PMID:34238924 RGD:10054119, RGD:153350155 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Crebbp CREB binding protein ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Egr1 early growth response 1 treatment IMP
IEP		 RGD PMID:22878149 PMID:23232597 RGD:10395282, RGD:10395299 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:17888675 RGD:10450582 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO mRNA:increased expression:lung (rat) RGD PMID:35600952 RGD:155663563 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Hmgb1 high mobility group box 1 IEP protein:increased expression:lung RGD PMID:22115333 RGD:10402095 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 IEP protein:increased expression:lung RGD PMID:21227458 RGD:10755577 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il1b interleukin 1 beta ameliorates IDA
ISO
IEP		 protein:increased expression:lung (rat) RGD PMID:23142117 PMID:34238924 PMID:23122581 RGD:7183185, RGD:153350155, RGD:7204125 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il4 interleukin 4 treatment IDA RGD PMID:24365768 RGD:10402797 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased activity:lung RGD PMID:18694576 RGD:5129703 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nos3 nitric oxide synthase 3 IMP
ISO		 mRNA:increased expression:lung (mouse) RGD PMID:20815765 PMID:25382268 RGD:4892012, RGD:11533932 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:21781312 RGD:6771212 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA
IEP		 protein:increased expression:alveolar macrophage (rat) RGD PMID:21781312 PMID:16449942 RGD:6771212, RGD:11541083 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19782612 RGD:11100035 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO
IDA		 protein:increased expression:plasma (human) RGD PMID:17846288 PMID:11606484 RGD:8547720, RGD:11080966 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Tlr4 toll-like receptor 4 treatment IEP RGD PMID:22115333 RGD:10402095 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor ameliorates IMP
ISO		 RGD PMID:17294835 PMID:34238924 RGD:4143397, RGD:153350155 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Zfp36 zinc finger protein 36 exacerbates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
meconium aspiration syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IEP mRNA:increased expression:lung RGD PMID:14605247 RGD:11039054 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 treatment IMP RGD PMID:14605247 RGD:11039054 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Atf2 activating transcription factor 2 ISS MouseDO NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO protein:increased expression:broncho-alveolar lavage fluid, meconium RGD PMID:21567110 RGD:5144123 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
pneumoconiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Atr ATR serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Car1 carbonic anhydrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Cat catalase ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:19273541 RGD:5130756 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cdh23 cadherin-related 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419 		JBrowse link
G H3f4 H3.4 histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr10:43,740,797...43,741,207 JBrowse link
G Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr10:13,781,999...13,788,133
Ensembl chr10:13,781,993...13,788,133 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21857939 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Mdm4 MDM4 regulator of p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphisms:cds:HLA-DQB1*06, HLA-DQB1*08, HLA-DQB1*09 (human) RGD PMID:16188098 RGD:7421557 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tmprss3 transmembrane serine protease 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25445010 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363 		JBrowse link
Pneumonia, Ventilator-Associated term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gc GC, vitamin D binding protein ISO protein:increased expression:bronchoalveolar fluid: RGD PMID:21136918 RGD:5509873 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
Pulmonary Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IEP protein:increased expression:alveolar system (rat) RGD PMID:16044083 RGD:11060268 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Il6 interleukin 6 IEP protein:increased expression:bronchoalveolar lavage fluid (rat) RGD PMID:16044083 RGD:11060268 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
Radiation Pneumonitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:1886988 RGD:4890434 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO associated with lung cancer;DNA:SNPs:promoter:���111G>A,126713G>A (rs189037, s373759) (human) RGD PMID:20171797 RGD:150340755 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G C3 complement C3 ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C4bpa complement component 4 binding protein, alpha ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G Cblb Cbl proto-oncogene B susceptibility ISO associated with lung non-small cell carcinoma; DNA:SNP,haplotype: :rs2305035(human) RGD PMID:26732495 RGD:150540334 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 IEP mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 IEP mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Il13 interleukin 13 susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNPs: :rs20541, rs180925 (human) RGD PMID:20811626 RGD:5131286 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il1a interleukin 1 alpha susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1800587,rs17561(human) RGD PMID:20811626 RGD:5131286 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Mif macrophage migration inhibitory factor susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNP: :rs755622(human) RGD PMID:20811626 RGD:5131286 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO associated with carcinoma, non-small-cell lung;DNA:SNP:cds:c.894G>T rs1799983 (human) RGD PMID:20811626 RGD:5131286 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Sftpd surfactant protein D susceptibility ISO RGD PMID:20459699 RGD:4143486 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 susceptibility ISO
IMP		 protein:increased expression:blood
DNA:SNP:exon:869T>C (rs1982073) (human)		 RGD PMID:19943923 PMID:18411002 PMID:19380441 RGD:4145121, RGD:4145278, RGD:4145136 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1799724(human) RGD PMID:20811626 RGD:5131286 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO RGD PMID:18347190 RGD:5131153 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Vtn vitronectin ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810 		JBrowse link
silicosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22273745 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Arg1 arginase 1 IEP
ISO		 mRNA:increased expression:lung (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15292275 PMID:17365572 RGD:4143368 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IEP mRNA:altered expression:lung (rat) RGD PMID:18685790 RGD:4893904 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G C3 complement C3 ISO DNA:polymorphism (human) RGD PMID:12096683 RGD:5129516 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cav1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36053221 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26163174 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 IEP RGD PMID:21830856 RGD:6483764 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Cd36 CD36 molecule treatment IMP RGD PMID:24053919 RGD:11041147 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Chia chitinase, acidic IEP mRNA:increased expression:lung (rat) RGD PMID:18685790 RGD:4893904 NCBI chr 2:193,614,374...193,656,532
Ensembl chr 2:193,614,114...193,656,533 		JBrowse link
G Cpm carboxypeptidase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:24986923 NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220 		JBrowse link
G Csf2 colony stimulating factor 2 IEP protein:increased expression:serum: RGD PMID:21505002 RGD:10450467 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO RGD PMID:16831302 RGD:4891515 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Egr1 early growth response 1 IEP protein:increased expression:lung, epithelial cell, macrophage (rat) RGD PMID:15033019 RGD:5131937 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eln elastin IEP protein:increased expression:lung connective tissue: RGD PMID:7573374 RGD:9585691 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Hmox1 heme oxygenase 1 ISO protein:increased expression:serum, lung RGD PMID:16858012 RGD:4145384 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 IEP protein:increased expression:lung RGD PMID:19534998 RGD:10059658 NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306 		JBrowse link
G Ift88 intraflagellar transport 88 IEP protein:decreased expression:lung RGD PMID:32042332 RGD:155791682 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147 		JBrowse link
G Il17a interleukin 17A ISO mRNA, protein:increased expression:lung RGD PMID:20421647 RGD:4888525 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23640035 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility
treatment		 ISO
IDA		 DNA:SNP (human) RGD PMID:11264025 PMID:23842733 RGD:4142816, RGD:8551847 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO RGD PMID:21072213 RGD:4891500 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27621875 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kif3a kinesin family member 3a IEP
ISO		 protein:decreased expression:lung
protein:increased expression:respiratory system fluid/secretion:		 RGD PMID:32042332 PMID:32042332 RGD:155791682, RGD:155791682 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191 		JBrowse link
G Marco macrophage receptor with collagenous structure treatment IMP RGD PMID:30391304 RGD:41412200 NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521 		JBrowse link
G Mmp13 matrix metallopeptidase 13 IEP mRNA:increased expression:lung, fibroblast RGD PMID:9614183 RGD:10043156 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15292275 PMID:15205031 RGD:4891445 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Pdzrn4 PDZ domain containing RING finger 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24986923 NCBI chr 7:123,816,961...123,965,491
Ensembl chr 7:123,816,961...123,965,491 		JBrowse link
G Prkcb protein kinase C, beta IDA protein:increased activation:alveolar macrophage RGD PMID:14680365 RGD:1625527 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27621875 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO DNA:polymorphism: :HLA-DQB1*0402(human) RGD PMID:11776400 RGD:36049758 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 IEP mRNA:decreased expression:lung (rat) RGD PMID:29230030 RGD:152977761 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Tert telomerase reverse transcriptase IEP mRNA:increased expression:lung (rat) RGD PMID:29230030 RGD:152977761 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP		 DNA:polymorphisms: : RGD PMID:11264025 PMID:25199287 RGD:4142816, RGD:10450591 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO RGD PMID:11208652 RGD:5131150 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO RGD PMID:11208652 RGD:5131150 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
Silicotuberculosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sting1 stimulator of interferon response cGAMP interactor 1 severity ISO RGD PMID:31141689 RGD:39128194 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
Ventilator-Induced Lung Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:19124556 RGD:5509080 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 IMP RGD PMID:18424620 RGD:6903342 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Axin2 axin 2 IEP RGD PMID:21935365 RGD:9685370 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Elane elastase, neutrophil expressed ISO RGD PMID:18276796 RGD:10450549 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO RGD PMID:19124556 RGD:5509080 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP associated with Endotoxemia RGD PMID:24058610 RGD:10402091 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:23890086 PMID:22106021 RGD:7364989, RGD:11049495 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta ISO
IDA
IMP		 protein:increased expression:lung RGD PMID:20574227 PMID:22007788 PMID:20452617 RGD:4142534, RGD:6482672, RGD:4142537 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 ISO RGD PMID:17901159 RGD:2311107 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IEP mRNA:increased expression:lung (rat) RGD PMID:22782699 RGD:6909178 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il22 interleukin 22 ISO RGD PMID:20463292 RGD:5147406 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP protein:hyperphosphorylation:lung: RGD PMID:24126891 RGD:10412643 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mmp7 matrix metallopeptidase 7 IEP RGD PMID:21567117 PMID:21935365 RGD:9685338, RGD:9685370 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:18223162 RGD:5130156 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nfkbia NFKB inhibitor alpha IEP RGD PMID:20199666 RGD:10413863 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:16374167 RGD:6482697 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:21048090 RGD:5134956 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO RGD PMID:15608088 RGD:5144143 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
G Serpine1 serpin family E member 1 IEP associated with Pneumonia, Pneumococcal;protein:increased expression:bronchoalveolar lavage fluid (rat) RGD PMID:18768578 RGD:11081010 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:20176632 RGD:5147811 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18246
    Wounds and Injuries 912
      Thoracic Injuries 276
        Lung Injury 271
          Acute Lung Injury 142
          Hyperoxic Lung Injury 12
          Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome 2
          Lung Reperfusion Injury + 27
          Pulmonary Contusion 2
          Radiation Pneumonitis 16
          Ventilator-Induced Lung Injury + 52
          meconium aspiration syndrome 4
          pneumoconiosis + 78
Path 2
Term Annotations click to browse term
  disease 18246
    disease of anatomical entity 17610
      respiratory system disease 3432
        lower respiratory tract disease 2267
          lung disease 2230
            Lung Injury 271
              Acute Lung Injury 142
              Hyperoxic Lung Injury 12
              Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome 2
              Lung Reperfusion Injury + 27
              Pulmonary Contusion 2
              Radiation Pneumonitis 16
              Ventilator-Induced Lung Injury + 52
              meconium aspiration syndrome 4
              pneumoconiosis + 78
paths to the root